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1 thetic challenge because of their ability to oligomerize.
2 activities are dependent on its capacity to oligomerize.
3 c stability of apoA-IV and its propensity to oligomerize.
4 veral MxB variants that lose the capacity to oligomerize.
5 onounced tendency of TatE and TatA to hetero-oligomerize.
6 in the Golgi apparatus and are able to homo-oligomerize.
7 and a partially folded intermediate that can oligomerize.
8 vity, but 4 of the 8 retained the ability to oligomerize.
9 the related ATPase SERCA, PLM is reported to oligomerize.
10 er RHL2 with little tendency to further homo-oligomerize.
11 y inactive enzyme that is fully competent to oligomerize.
12 ctin is present in a protein complex and can oligomerize.
13 displays a markedly increased propensity to oligomerize.
14 motif (SAM) domain and shows a propensity to oligomerize.
15 n, and that the binding causes fibrinogen to oligomerize.
16 gether with the adjacent helical region homo-oligomerize.
17 interaction is lost when Cox15 is unable to oligomerize.
18 ncreased also, suggesting that Py-A54145 had oligomerized.
19 the strand segments are immobilized and thus oligomerized.
20 Here we show that AIM PYD (AIM2(PYD)) self-oligomerizes.
21 N1-N9) and the prior knowledge that a N1 TMD oligomerizes.
22 ide evidence that ARFs have the potential to oligomerize, a property that could be important for gene
25 Moreover, because all Bax molecules became oligomerized after membrane insertion, we infer that Bax
27 Moreover, we show that full-length STING oligomerizes after it binds cGAMP, and highlight this as
28 to GPP130 in the Golgi and causes GPP130 to oligomerize/aggregate, and the complexes are diverted to
29 IL are clustered on the exosomal membrane as oligomerized aggregates ready to form death-inducing sig
30 ese results are emphasized by simulations of oligomerized amphiphysin N-BARs at the atomistic and coa
33 in stromal interaction molecule 1 (STIM1) to oligomerize and accumulate within endoplasmic reticulum-
34 RbAB translates into a propensity to rapidly oligomerize and aggregate at 37 degrees C (T50 = 28 min)
36 d markedly in their stability, propensity to oligomerize and apparent modes of initiation, and the ol
37 haliana CURT1 proteins (CURT1A, B, C, and D) oligomerize and are highly enriched at grana margins.
39 S remained or re-directed in the nucleus can oligomerize and behave similarly to the wild-type FUS pr
40 omerize upon GAG binding, and the ability to oligomerize and bind GAGs is required for in vivo functi
41 constitution with mutants of Bax that cannot oligomerize and form apoptotic pores, but still enhance
42 ype CORO1A in normal lymphocytes but did not oligomerize and had impaired cytoskeletal association.
44 on studies then revealed that these proteins oligomerize and interact through a dense network of cont
45 into the structural origin of its ability to oligomerize and interact with phospholipid bilayers, pro
46 demonstrated that ASB-Cullin 5 complexes can oligomerize and provides evidence that Cullin 5 forms he
47 f full-length NS1A from different strains to oligomerize and results in a reduction in dsRNA binding
48 l unclear, insight as to how these receptors oligomerize and the relevance of the lipid environment t
50 ot BAX) in lymphohematopoietic cell lines is oligomerized and bound to anti-apoptotic BCL2 family mem
52 emperature, alkanes and alkenes are facilely oligomerized and isomerized at high conversions (>97 %),
59 which recognizes H3K9-methylated chromatin, oligomerizes and forms a versatile platform that partici
60 s: canonical holins, like lambda S105, which oligomerizes and forms large membrane holes of unprecede
62 ) is a model alpha-PFT from sea anemone that oligomerizes and forms pores in sphingomyelin-containing
64 provide a unique comparison set because CCL2 oligomerizes and oligomerization is required for its ful
65 s from the cytosol to mitochondria, where it oligomerizes and permeabilizes the mitochondrial outer m
66 these data support the hypothesis that EXP2 oligomerizes and potentially forms the putative membrane
69 teins spread extracellularly, become seeded, oligomerize, and are taken up by cells, depends on intri
70 ought to first bind to the membrane, then to oligomerize, and finally to detach, in a stringently reg
72 ivity of the Dam1c depends on its ability to oligomerize, and the purified complex spontaneously self
73 Ag, a portion of MBC receptors spontaneously oligomerized, and phosphorylated kinases accumulated at
74 t binds to cholesterol-containing membranes, oligomerizes, and forms a beta-barrel transmembrane pore
75 into the mitochondrial outer membrane (MOM), oligomerizes, and induces MOM permeabilization, causing
76 which Sec17 binds to trans-SNARE complexes, oligomerizes, and inserts apolar loops into the apposed
77 e show that the coiled-coil domain of AtZAR1 oligomerizes, and this domain acts as a signal to induce
78 a more favorable setting in which GPCRs can oligomerize as a prelude to nucleation and crystal growt
81 tion, pointing to the possibility that GerBC oligomerizes as a result of either high local protein co
82 of LRRK2 bearing a pathogenic mutation that oligomerizes as a right-handed double helix around micro
83 ically dead PfClpP, which showed that PfClpP oligomerizes as a zymogen and is matured via transautoca
85 tic protein RIBEYE suggest that monomers can oligomerize at the level of the IS before ribbon assembl
87 tant was still able to bind to membranes and oligomerize at the same level as the wild-type or the re
89 is is likely due to the inability of CCL7 to oligomerize because CCL2(P8A) also binds significantly l
92 and generality of this translation system by oligomerizing building blocks including polyethylene gly
94 icroscopy and cellular studies revealed that oligomerized, but not monomeric, beta-arrestin2 increase
95 nal self-diffusion rates indicate that CCL27 oligomerizes, but in contrast to many other chemokines t
96 es, we learn that hydroxyanions dimerize and oligomerize by overcoming long-range electrostatic oppos
97 om the P subfamily (FoxP) show that they can oligomerize by three-dimensional domain swapping, whereb
99 ding studies with GpL-FLAG-TNC-TWEAK trimers oligomerized by help of a FLAG tag-specific antibody gav
103 air by cGAS is linked to its ability to self-oligomerize, causing compaction of bound template dsDNA
104 This indicates that the higher activity of oligomerized CD95L trimers is not related to an avidity-
105 hought to mediate many cellular processes by oligomerizing cell surface glycoproteins and glycolipids
108 ominantly of three proteins that form highly oligomerized concentric rings spanning the inner and out
109 Our results suggest a physiological role for oligomerized condensin in driving gradual chromatin comp
117 uronal cell line, mild overexpression of the oligomerizing E57K alpha-Syn variant significantly impai
118 r nanocomplex is obtained by complexation of oligomerized EGCG with the anticancer protein Herceptin
120 We selected a green tea catechin derivative, oligomerized (-)-epigallocatechin-3-O-gallate (OEGCG) as
122 identical aggregation mechanisms, the latter oligomerized faster due to lower solubility and, hence,
125 s with a "nonproductive" dimer that does not oligomerize further (tau(ex) ~ 400 mus; K (diss) ~ 0.3 M
126 ling complexes ("signalosomes") assembled by oligomerizing hub proteins following their recruitment t
128 xperiments in HEK-293 confirm that NCS-1 can oligomerize in cell lysates and that oligomerization is
129 These results suggest that beta2ARs do not oligomerize in cells, and demonstrate a reliable method
130 ponse to IP(6), the two non-visual arrestins oligomerize in different ways in distinct conformations.
133 tion.Moreover, the ability of the protein to oligomerize in solution was found to correlate with tran
134 and function as oligomers, but how monomers oligomerize in the cell membrane remains poorly understo
137 s evidence that purified full-length Syt1 is oligomerized in the membrane, and mutagenesis indicates
147 ere we show that the DEAD-box helicase Ded1p oligomerizes in the cell and in vitro, and unwinds RNA a
148 exin26 (Cx26) is a gap junction protein that oligomerizes in the cell to form hexameric transmembrane
149 RE1 activation are conserved: mammalian IRE1 oligomerizes in the ER membrane and oligomerization corr
152 ilament, also has an intrinsic propensity to oligomerize into an elongated structure that activates t
153 R2 mainly exists as a dimer that can swiftly oligomerize into an octamer depending on local protein c
156 larly to holins, CidA and LrgA were found to oligomerize into high-molecular-mass complexes whose for
158 Furthermore, the propensity of dynamin to oligomerize into higher-order structures in an actin-dep
159 mprise a family of GTP-binding proteins that oligomerize into higher-order structures, which associat
164 herichia coli Activated transmembrane dimers oligomerize into small holes and uncouple the proton gra
166 r journey as soluble monomeric proteins, and oligomerize into transmembrane complexes to eventually f
167 the related nematode Caenorhabditis remanei oligomerizes into a decameric assembly that appears roug
168 pported by experimental data: first, dynamin oligomerizes into a helical polymer; second, dynamin oli
169 pon binding to cytochrome c and dATP, Apaf-1 oligomerizes into a heptameric complex known as the apop
174 th diverse cellular activities) protein that oligomerizes into single hexameric rings in the presence
177 receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signa
178 ce on cGAS and sterically prevents cGAS from oligomerizing into the functionally active 2:2 cGAS-dsDN
181 ce for a major increase in Fn14 occupancy by oligomerized ligand despite strongly enhanced induction
182 ed diffusion is due to conserved features of oligomerized MACPF proteins, which may include an anioni
184 nal studies showed that G51D alpha-synuclein oligomerizes more slowly and its fibrils are more toxic
186 type arrestin-1 in living animals with a non-oligomerizing mutant retaining all other functions.
187 uired for a specific interaction between the oligomerized NHR2 domain and a novel NHR2-binding (N2B)
188 ucleus, as well as inhibiting its ability to oligomerize, not only neutralizes NPM1 toxicity but also
191 They are secreted as soluble monomers that oligomerize on target membranes in the so-called prepore
192 eleased as water-soluble monomers that first oligomerize on the membrane before inserting a transmemb
193 talytically active monomers or dimers slowly oligomerize on the viral genome and inhibit reverse tran
196 ges in the local environment of SP1 when Gag oligomerizes on nucleic acid might trigger this switch.
197 e monomeric protein secreted by the bacteria oligomerizes on the surface of the target cell, and the
202 y other activities of soluble TWEAK, whereas oligomerized or FcgammaR-bound Fn14 antibodies fully mim
205 a in the neuropil and that this synaptotoxic oligomerized peptide is present at a subset of synapses.
206 Arabidopsis ADH1 and TT4 genes were made by Oligomerized Pool ENgineering (OPEN)-a publicly availabl
208 malignancies, regulate the ability of NS to oligomerize, prevent its degradation, and may alter its
209 equently, cIAP1 cooperatively interacts with oligomerized processed caspase-9 in the apoptosome and b
211 show that CALM-AF10 has a propensity to homo-oligomerize, raising the possibility that the function o
212 agged, optogenetic Amyloid-beta peptide that oligomerizes rapidly in the presence of blue light.
214 ssed, but in the presence of its ligands, it oligomerizes, recruits apoptosis-associated speck-like p
216 (NC), built on a foundation of three highly oligomerized ring-forming proteins that create a hollow
217 have been derived from structural studies of oligomerized, RNA-encapsidating nucleoprotein, and cryo-
219 we demonstrate that full-length kindlins can oligomerize (self-associate) in mammalian cells, and we
222 TNFR2 activation, we constructed differently oligomerized single chain TNF ligands (scTNF) comprised
225 er N terminus correlates with the ability to oligomerize, store iron, and form stable contacts with N
227 ms of protection induced by the treatment of oligomerized T cell epitope of myelin proteolipid protei
229 osynthetic pathway by which it progressively oligomerizes tetradepsipeptidyl substrates to a dodecade
230 We furthermore show that diffusive JPO2 can oligomerize; that JPO2 and LEDGF/p75 interact directly a
232 Bacterial enhancer-binding proteins (bEBPs) oligomerize through AAA(+) domains and use ATP hydrolysi
234 SWAP-70 is an F-actin-bundling protein that oligomerizes through a Gln/Glu-rich stretch within a coi
235 d that the transmembrane domain of FtsB homo-oligomerizes through an evolutionarily conserved interac
236 lacking all cytosolic domains (STIM1-DeltaC) oligomerizes through EF-SAM interactions alone, but thes
238 the interface of mTOR complex 1 dimer, which oligomerizes through two spatially separate interfaces.
239 rtially buried when CCL3, CCL4, and CCL5 are oligomerized; thus, the mechanism by which GAG binds the
240 inal truncated SAA2.2 (SAA2.2DeltaC) did not oligomerize to a hexamer or octamer, but formed a high m
241 e their ability to insert into membranes and oligomerize to create the large curvatures; however, the
242 during procapsid morphogenesis, 10 proteins oligomerize to form a DNA translocating conduit (H-tube)
243 y ATPases to date have one ATPase domain and oligomerize to form a functional molecular machine, most
245 proteins of about 110 residues that need to oligomerize to form a structural pathway for substrate e
248 ns bind to target membranes and subsequently oligomerize to form functional pores that eventually lea
251 In Schwann cells, connexin 32 (Cx32) can oligomerize to form intracellular gap junction channels
252 p4 and any mixture of the 56- and 63-kDa gp4 oligomerize to form more hexamers than does the 63-kDa g
254 a class of pathogen-secreted molecules that oligomerize to form transmembrane channels in cellular m
256 ith DnaA contacting low affinity sites as it oligomerizes to 'fill the gaps' between high affinity si
257 of ER stress, the transmembrane protein Ire1 oligomerizes to activate its cytoplasmic kinase and ribo
258 -forming component, protective antigen (PA), oligomerizes to create a prechannel that forms toxic com
259 s, full-length (fl) mouse TIA1 spontaneously oligomerizes to form a metastable colloid-like suspensio
261 ere we show that the PhiX174 pilot protein H oligomerizes to form a tube whose function is most proba
262 Similar to other nacre proteins, rPFMG1 oligomerizes to form amorphous, heterogeneously sized pr
263 e attack complex/perforin (MACPF) domain and oligomerizes to form an aqueous pore in the plasma membr
264 The hepatitis C virus (HCV) viroporin p7 oligomerizes to form ion channels, which are required fo
265 (ORF54) gene encodes an 87-kDa monomer that oligomerizes to form the VZV portal protein, pORF54.
266 y adenosine triphosphates to unwind helices, oligomerizes to function as efficient RNA helicase, and
267 The structure of full-length M1, and how it oligomerizes to mediate the assembly of virions, is unkn
268 fted features only emerge when the ion pairs oligomerize together into larger (TOTA.[CS2BF4])n assemb
269 al IL8 production, more than 2500 cell-bound oligomerized TWEAK trimers were required to elicit a sim
270 contemporary biomonomers don't spontaneously oligomerize under mild conditions without activation or
273 upled receptors as monomers, many chemokines oligomerize upon GAG binding, and the ability to oligome
275 low measurements revealed that Atg18 rapidly oligomerizes upon membrane binding while it is mainly mo
277 nity similar to CCL2 but higher than the non-oligomerizing variant, CCL2(P8A), suggesting that, in co
280 te binding in specifying Gle1 function, Gle1 oligomerizes via its N-terminal domain in a phosphorylat
282 experiments mimics the process by which VacA oligomerizes when in contact with membranes of host cell
283 ependent membrane recruitment causes FGF2 to oligomerize, which in turn triggers the formation of a l
285 inactive variant (alphaKAP) that can hetero-oligomerize with and target active enzyme to membranes.
287 data furthermore reveals that Ycg1 tends to oligomerize with increasing concentrations in the absenc
288 lasmic reticulum after synthesis, where they oligomerize with other binding partners, such as alpha a
289 The mutant Prph2 protein lost the ability to oligomerize with rod outer segment membrane protein 1 (R
290 ment of CLL cells with Wnt5a induced ROR1 to oligomerize with ROR2 and recruit guanine exchange facto
291 of which have an equal propensity to hetero-oligomerize with SEPT7-containing hexamers to generate o
293 ently split fragments of NiV, RSV, and MeV L oligomerized with comparable efficiency in all homo- and
296 onstrated that the PNKD long isoform monomer oligomerizes with itself as well as interacts with the s
297 2 homolog, also has a RING domain and hetero-oligomerizes with Mdm2 to stimulate its E3 ligase activi
298 death-domain-containing adaptor protein that oligomerizes with PIDD and caspase-2 to initiate apoptos
299 s show that the transmembrane helix of ADCK3 oligomerizes, with an interface based on an extended Gly
300 copy (AFM) imaging to show that MAC proteins oligomerize within the membrane, unlike structurally hom