ライフサイエンスコーパス: onset

1 speed of the VO2 kinetics following exercise onset.

2 nd subsequently potentially impact psychosis onset.

3 .0%-98.3%) for samples >14 days post symptom onset.

4 cific serum IgA and IgG titers after symptom onset.

5 titive rotations and head tics with juvenile onset.

6 invasive brain voltage recordings at seizure onset.

7 ty who presented within a week after symptom onset.

8 icrobials would remain effective after fever onset.

9 rmally expressed in hair cells prior to GFI1 onset.

10 ct genetic influences on GBA risk and age at onset.

11 ) is limited, and most studies focus on ARDS onset.

12 igh sensitivity close to the age of clinical onset.

13 nostic delay is up to 5-6 years from symptom onset.

14 proteolytic and elastase activity before UC onset.

15 itiated from 0 to up to 30 hours after fever onset.

16 nts with lesion age < 4.5 hours from symptom onset.

17 ment was started within 7 days after symptom onset.

18 nic isolated proteinuria and early childhood onset.

19 epertoires of an Ebola survivor from disease onset.

20 rylation by CDK-1 occurs just before meiotic onset.

21 educed the expression of IRGs during disease onset.

22 ing samples collected >14 days after symptom onset.

23 ey take several weeks to achieve therapeutic onset.

24 sleep onset and subjective latency to sleep onset.

25 to >80% between days 6 and 10 after symptom onset.

26 of the 334 patients (51%) developed LEE (new onset, 120; worsened edema, 50).

27 We found that the target evoked N2pc onset ~20 ms earlier when the target location was cued t

28 l activation metrics were predictive of GVHD onset 3-6 wk before phenotypic pathology.

29 ptom after a mean of 125 days after symptoms onset, 33.3% reported one or two symptoms and 19.4% thre

30 sequently developed symptoms (median time to onset, 4 days).

31 bnormal MRI findings 2-4 weeks after symptom onset (58.9%), including 17 with acute ischemic infarct

32 results in at least some of the hira-1 late-onset abnormalities.

33 or PSEN2) carrying mutations linked to early-onset AD.

34 Moreover, we show that post-disease-onset administration of the type 2 diabetes medication m

35 ve hypotension, which is associated with new-onset, adverse kidney-related outcomes.Study registered

36 risk; these factors also affect risk for CRC onset after age 50.

37 ups, without any comparable dramatic peak of onset age.

38 ects models to explore differences in age at onset, age at death, and disease duration between geneti

39 Late onset Alzheimer disease (LOAD) is traditionally consider

40 anisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integr

41 n genome-wide significant risk loci for late-onset Alzheimer's disease (LOAD).

42 er airway prior to or at the time of symptom onset, an unusual feature that has enabled widespread tr

43 s, and oxidative stress associated with both onset and advancement of cardiac dysfunction in T1D.

44 icantly correlated with both parental age at onset and at death and with mean family age at onset and

45 te the extent to which variability in age at onset and at death could be accounted for by family memb

46 set and at death and with mean family age at onset and at death in all three groups, with a stronger

47 Individual age at onset and at death was significantly correlated with bot

48 binocular circuit present at critical period onset and building it anew.

49 cal yet poorly understood forms of childhood-onset and complex hereditary spastic paraplegia: SPG47 (

50 Based on the timing of onset and detection, perioperative stroke can be classif

51 patients, even minor delays between symptom onset and first injection led to less optimistic vision

52 s found in the reduction of wake after sleep onset and latency to persistent sleep from baseline to d

53 by age in youths aged 6 to 20 years and the onset and magnitude of divergence in levels between boys

54 ramping up slowly over 500 ms after stimulus onset and peaking at ~800 ms, around response selection

55 causal processes that contribute to disease onset and progression is essential for developing novel

56 roposed to be a key pathogenic factor in the onset and progression of Alzheimer's disease (AD).

57 Major corticofugal tracts are crucial to the onset and progression of amyotrophic lateral sclerosis.

58 al traits, particularly those related to the onset and progression of human disease.

59 how microstructure and mechanics change with onset and progression of POP.

60 Age affects its onset and progression.

61 ps of neurodegeneration as well as in cancer onset and progression.

62 stic cells, which leads to pancreatic cancer onset and progression.

63 er's disease, inextricably linked to disease onset and progression.

64 chup1 and analyzed the kinetics of both the onset and recovery of NPQ under equivalent intensities o

65 lerance, protects against insulin-resistance onset and remarkably reverses already established insuli

66 psychosis (FEP), but their role in psychosis onset and response to antipsychotic treatment is unclear

67 jor Notch downstream targets, especially the onset and sequence in which they are modulated during no

68 Patients with LGMDR3 had a later onset and slower progression of the disease.

69 d to reduce the critical gap between disease onset and start of treatment.

70 ere observed for subjective wake after sleep onset and subjective latency to sleep onset.

71 halitis, it usually has an acute or subacute onset, and antipsychotic treatment may be ineffective an

72 cs, dose of the at-risk GH, age at treatment onset, and duration of the incubation period.

73 models became significant early after image onset, and identity across a change in facial expression

74 with immunoglobulin titers following symptom onset, and positive percent agreement between detection

75 uld be closely monitored for growth, puberty onset, and potential pituitary deficiency.

76 ctivation shifts from reward delivery to cue onset, and provide insight into the maladaptive nature o

77 duration, sleep duration variability, sleep onset, and sleep onset variability were assessed across

78 sed disability), at 6-10 years after disease onset, assessed with a linear mixed-effects model.

79 .74) was associated with reduced risk of new-onset asthma.

80 c variables to clinical factors improved new-onset atrial fibrillation discrimination in a multivaria

81 ics, medical history, and development of new-onset atrial fibrillation during the first four days of

82 ic susceptibility contributes to risk of new-onset atrial fibrillation in the ICU.

83 ) remained significantly associated with new-onset atrial fibrillation.

84 ents from five unrelated families with early onset autoimmune manifestations.

85 2 (LRRK2) are the most common cause of late-onset, autosomal-dominant familial Parkinson's disease (

86 Young-onset breast cancers (YOBC) tend to be aggressive and ma

87 ons from baseline firing shortly after image onset but relaxing back to baseline at different rates.

88 are intimately linked with premature disease onset but the underlying mechanisms remain poorly unders

89 axis changes are associated with depression onset, but the mechanisms underlying this observation re

90 ction of gut microbial communities and early-onset calcium oxalate kidney stone disease is unknown.

91 Among survivors of adult-onset cancers in the United States, several types of pri

92 er cells, perturbation of which causes early-onset cataracts.

93 No late-onset cCMVI-related HL was detected during a median foll

94 differed between patients on a GFD with new-onset CD vs healthy children were associated with nutrie

95 The incidence of early-onset colorectal cancer (CRC), which occurs in individua

96 ncidence of breast cancer and younger age of onset compared to the general population, it is recommen

97 Delta3A virus caused lymphomas with delayed onset compared to the onset of those caused by WT EBV, a

98 he prediction of renal disease in the 'later onset' compared with the 'earlier onset' group.

99 from 5/8 KD patients day >= 8 after illness onset, compared with 0/17 infant controls (P < .01), rec

100 net reclassification improvements for early-onset coronary heart disease, atrial fibrillation and pr

101 ates, but risk factors associated with early-onset CRC (EOCRC) have not been widely studied.

102 th diabetes, who are at higher risk of early-onset CRC than the general population.

103 ndrial stress likely contributes to the late-onset defects, given that hira-1 mutants display mitocho

104 ementia (bvFTD) is a frequent cause of early-onset dementia.

105 ance and insulin secretion) to cluster adult-onset diabetes patients into five subtypes.

106 All patients had neonatal/early-onset diabetes, severe microcephaly, and epilepsy.

107 cific antibodies protect newborns from early-onset disease, yet their impact on GI colonization and L

108 ith COVID-19 symptoms (<=7 days from symptom onset [DSO], >=18 years of age) were utilized to compare

109 everely affected patients with early disease onset due to point mutations in the PLP1 gene, and absen

110 ited in the nucleus reuniens at the UP state onset during slow oscillations.

111 erve to increase the likelihood of psychosis onset during this period, while others may buffer this r

112 classified into one or more subtypes: early onset (EO), lethal, and/or clinically significant.

113 gut microbiota, resulting in either disease onset/exacerbation due to a "poor" diet or protection ag

114 me that GnRH agonist treatment after puberty onset exerts sex-specific effects on social- and affecti

115 y in individuals closer to expected clinical onset (FDR <0.0001).

116 Late-onset FECD is a uniquely advantageous model for studying

117 ental sonographic screening to predict early-onset FGR.

118 oantibodies among unselected people with new-onset focal epilepsy.

119 and doxycycline were administered upon fever onset for 10 days.

120 ective response within 6 months of treatment onset; for osteosarcoma, a dual primary endpoint of 6-mo

121 e study enrolled TIA patients within 72 h of onset from the prospective TIA database of the First Aff

122 the 'later onset' compared with the 'earlier onset' group.

123 We also idenified a third onset-hastening modifier signal whose mechanism of actio

124 ameters (GAD autoantibodies, age at diabetes onset, HbA(1c), BMI, and measures of insulin resistance

125 ry endpoints included incidence of community-onset healthcare facility-associated CDI (CO-HCFA-CDI),

126 he majority of patients hospitalized for new-onset HF did not receive testing for CAD either during t

127 CH is more common in individuals with adult-onset HLH and can contribute to the pathophysiology of t

128 ght explain the missing heritability of late-onset human diseases, such as Alzheimer's disease, Parki

129 (<40%) within the first 5 days after disease onset, immunoglobulin (Ig) M, IgA, and total antibody EL

130 of the LH surge at least 2 days prior to its onset in 100% of individuals.

131 al surveillance case definition, had illness onset in 2016 or 2017, resided in a participating state,

132 in DYT/PARK-TAF1 and younger age at dystonia onset in DYT-SGCE.

133 dystonia duration and older age at dystonia onset in DYT-TOR1A, longer dystonia duration in DYT/PARK

134 Disease onset in females occurred across all age groups, without

135 nt genome-wide association studies of age-at-onset in Huntington's disease (HD) point to distinct mod

136 SCA13 exists in distinct forms with onset in infancy or adulthood.

137 Group activity during video onset in only a subset of these regions, however, foreca

138 Of these infections, 517,818 (83%) had their onset in the community, and 104,572 (17%) had their onse

139 n the community, and 104,572 (17%) had their onset in the hospital.

140 show as-deposited FAPI films have absorption onsets in the near infra-red with a direct bandgap value

141 Adult-onset inflammatory syndromes often manifest with overlap

142 rder that connects seemingly unrelated adult-onset inflammatory syndromes.

143 Late-onset inflammatory toxicities resembling hemophagocytic

144 Lupus onset initiated major changes to the platelet transcript

145 mation, we found that, although inflammatory onset is similar between young and elderly individuals,

146 he quality of late-phase (>150 ms from image onset) IT population code and produced commensurate beha

147 At failure onset, it may be difficult to forecast the final eruptio

148 Adult-onset KD (AKD) is rare and often misdiagnosed.

149 ting peptide 1 (CSP1) failed to modulate the onset kinetics of competence development in vivo The com

150 lysis, treatment within 7 days after symptom onset led to lower 90-day mortality than use of placebo

151 n acute ischemic stroke with unknown time of onset, magnetic resonance (MR)-based diffusion-weighted

152 contribute to their increased risk for adult onset metabolic diseases, such as diabetes and obesity.

153 rs old; lesional and nonlesional) with early-onset moderate-to-severe AD (<=6 months) and 17 healthy

154 DNA damage onset most likely arises from formaldehyde, an obligate

155 P209L mutation results in a severe childhood-onset myofibrillar myopathy (MFM) associated with progre

156 The development of novel therapies for adult-onset neurodegenerative disease has been impeded by the

157 Early-onset neurodevelopmental conditions (e.g., autism) affec

158 (CSPalpha) cause dominantly inherited adult-onset neuronal ceroid lipofuscinosis (ANCL), a rapidly p

159 lygynous societies, we find that neither the onset nor the rate of senescence in body mass or reprodu

160 ated median age at mild cognitive impairment onset of 44 years), although the ability of plasma NfL t

161 oss-sectional design, 36 patients with first onset of a depressive disorder (Diagnostic and Statistic

162 and enhanced social skills stemmed from the onset of a more basic cognitive ability such as recursiv

163 and typically occurs 3 to 5 weeks after the onset of acute pancreatitis.

164 l of Abeta fibrillization to investigate the onset of AD over a long timescale.

165 ataracts, but there was no evidence of early onset of age-related cataracts in DS.

166 his trajectory was associated with the early onset of allergic sensitization.

167 llogeneic PITx and significantly delayed the onset of allograft loss.

168 fibrillary tangle (NFT) pathology during the onset of Alzheimer's disease (AD).

169 amyloid-beta peptide plays a key role in the onset of Alzheimer's disease.

170 sure to species richness at baseline and the onset of asthma and wheezing at the age of 7.

171 with herpesvirus reactivation and subsequent onset of autoimmune diseases(1-4).

172 Such electrical signals, which represent the onset of biofilm formation, were dynamically detected by

173 or inflammation and adaptive immunity in the onset of cancer and in shaping its response to therapy.

174 than that of non-carriers, while the age at onset of carriers with other gene pathogenic/likely path

175 In contrast, EASIX at the onset of cGVHD was not associated with cGVHD severity bu

176 We identify a phenomenon where the onset of channel flow creates an unexpected, charge-depe

177 Following the onset of choice-related activity, the robustness of the

178 Th17 cells arrive before the onset of clinical symptoms, distribute uniformly during

179 ccine preventable and treatable prior to the onset of clinical symptoms.

180 omplications: paravalvular leakage (PVL) and onset of conduction abnormalities leading to permanent p

181 term prospective studies from infancy to the onset of COPD.

182 Since the onset of coronavirus disease 2019, the potential risk of

183 Faster cooling rate resulted in an earlier onset of crystallization and ultrasonic treatment narrow

184 eneity to this progression of glycemia after onset of diabetes, yet the factors that influence glycem

185 ular dynamics simulations indicated that the onset of diffusion is due to an abrupt decrease in the f

186 stered intranasally to mice led to the rapid onset of disease symptoms and resulted in 90% mortality.

187 ctions, are usually required to initiate the onset of disease.

188 vidence of immune abnormalities before motor onset of disease.

189 End points were any progression of DR, onset of DR, and progression from mild to severe DR trac

190 ntifying a subgroup of children having early onset of each initial autoantibody, i.e., IAA-first by 1

191 ier mineral disengagement and the subsequent onset of fibril sliding is one of the key mechanisms lea

192 -dependent accumulation 2 to 4 min after the onset of flow.

193 rmation about previous treatments before the onset of GMG, and (4) had incomplete or lost medical rec

194 o circulating wild-type varicella delays the onset of herpes zoster, predicts a transient increase in

195 lute abundances were significantly higher at onset of ILI (p<0.01), and remained elevated beyond reco

196 rafficking factors, including RAB27B, at the onset of implantation.

197 measurements in the first 72 hours from the onset of infection.

198 re vital signs have been used to monitor the onset of infectious disease.

199 ) T cells that infiltrate the ganglia at the onset of latency and contract to a stable activated tiss

200 ceptor antagonists significantly delayed the onset of lethal seizures but did not prevent them.

201 that contribute to both LOAD risk and age at onset of LOAD.

202 stages, with energy constraints limiting the onset of male reproduction but playing a large role in f

203 The concurrent increase in the onset of many mental disorders has prompted the search f

204 kout mouse model to deplete EWSR1 before the onset of meiosis and found that absence of EWSR1 causes

205 ctation success in women at risk for delayed onset of milk production.

206 est that people can recognize the intent and onset of motion by inferring its early warning signals.

207 otentially related exposures may trigger the onset of nonfatal myocardial infraction.

208 GMG, (2) were unable to identify the time of onset of OMG or GMG, (3) were unable to provide informat

209 f DPP4 inhibitors and GLP-1 mimetics and the onset of Parkinson's disease (IRR 0.64; 95% CI 0.43-0.88

210 Specifically, the age at onset of Parkinson's disease patients with pathogenic/li

211 al tissues are often early indicators of the onset of pathological conditions.

212 in the winter of 2015/2016 led to a February onset of plant growth and the ecosystem became a sustain

213 d in spring due to a warming-induced earlier onset of plant growth, but decreased in autumn due mainl

214 is not known if they are present before the onset of psychosis or whether they are associated with p

215 ecimen at zero electron exposure, before the onset of radiation damage.

216 time in the Drosophila germband predict the onset of rapid cell rearrangement in both wild-type and

217 ich could explain the observed delays in the onset of relaxation.

218 -vascular dysfunction typically precedes the onset of retinal vascular and even some neurodegenerativ

219 ovascular treatment within 8 hours after the onset of stroke symptoms in conjunction with standard ca

220 tial serum samples collected up to 94 d post onset of symptoms (POS) from 65 individuals with real-ti

221 ly associated with viral load was time since onset of symptoms.

222 vaccination in children aged 28-275 days at onset of symptoms.

223 be detected in cases of ATL years before the onset of symptoms.

224 ricles and at all ages, including before the onset of systemic hypertension.

225 Furthermore, the age at onset of the 132 probands with genetic diagnoses (median

226 sient activation of action potentials at the onset of the blocking current.

227 he role of IL-4/IL-13 signaling prior to the onset of the disease and during the effector phase in th

228 with IBD activity and they even precede the onset of the intestinal disease, while episcleritis are

229 lizing subunit calstabin-1 6 hours after the onset of the mechanical ventilation, 1 and 10 days after

230 ctosidase (beta-Gal) deficiency and clinical onset of the neurodegenerative lysosomal storage disease

231 Treatment with NS9283 restores the rapid onset of the postsynaptic cholinergic response without t

232 state at [Formula: see text], preceding the onset of the spontaneous ferromagnetism, implying that b

233 ion quantitative trait loci, given the early onset of these disorders.

234 lymphomas with delayed onset compared to the onset of those caused by WT EBV, although the tumors occ

235 nd spinodal decomposition via the sequential onset of topological transitions.

236 We show in awake behaving mice that the onset of tremor is coincident with rhythmic Purkinje cel

237 The insidious onset of type 2 diabetes delays diagnosis and increases

238 ntion modalities to prevent the presence and onset of VI, and subsequent VRQoL declines, in these ind

239 such that they guide development before the onset of vision.

240 ned ATP7B mutants and, hence, to counter the onset of Wilson disease.

241 ns, including those who have exhibited early onset or accelerated cardiac allograft vasculopathy.

242 whether torsinB expression levels impact the onset or severity of abnormal movements or neuropatholog

243 : enhancement through (1) expedited decision onset, or (2) an increase in the quality of sensory evid

244 ced plasmas even at early times after plasma onset owing to favorable temperatures for molecular form

245 tations in Parkin are a major cause of early-onset Parkinson's disease (PD).

246 f the HMT and the CAT samples along with the onset, peak, and conclusion temperatures of gelatinizati

247 biased transcriptional profiling in an adult-onset Pkd2 mouse model before cysts formed revealed sign

248 ries evoked a widespread response at episode onset, plus a marked offset response specific to DMN reg

249 mdesivir starting 24 and 45 days after fever onset, pneumonia and spiking fevers remitted, but relaps

250 CMV disease-associated costs due to delayed onset post-prophylaxis disease in the prophylaxis group.

251 The 2D-GMs are formed at low onset potential and can be in situ doped depending on th

252 reversible hydrogen electrode (RHE) with an onset potential of 0.55 V vs. RHE and a record high half

253 Treatment after disease onset potently blocks progression of disease and further

254 rein, we have identified a new form of early-onset PRA (EOPRA) in the same breed.

255 o of those patients (78.6%) reported symptom onset prior to or in conjunction with the molecular diag

256 lic variants in UNC45B who exhibit childhood-onset progressive muscle weakness.

257 s lacking functional autophagy develop early onset progressive neurodegeneration.

258 group (r=0.22 individual and parental age at onset, r=0.18 individual and mean family age at onset, r

259 et, r=0.18 individual and mean family age at onset, r=0.22 individual and parental age at death, and

260 group (r=0.32 individual and parental age at onset, r=0.36 individual and mean family age at onset, r

261 et, r=0.36 individual and mean family age at onset, r=0.38 individual and parental age at death, and

262 63 between individual and mean family age at onset, r=0.58 between individual and parental age at dea

263 =0.45 between individual and parental age at onset, r=0.63 between individual and mean family age at

264 V light avoidance in anticipation of evening onset relative to females.

265 Cohort (CSC, n=446): patients developing new-onset renal function deterioration 7.7 +/- 5.6 years pos

266 ecessive Leber congenital amaurosis to later onset retinitis pigmentosa.

267 d to power spectra of the LFPs near stimulus onset revealed a broadband component (1-100 Hz) and two

268 e relation of baseline weight suppression to onset risk of each eating disorder controlling for age,

269 k of functional dependence at 3 months after onset (RR per year 0.983; 95% CI 0.968-0.998; p = 0.002

270 Whereas late-onset RTD may mimic different acquired or genetic causes

271 ith major infection at 1 year in one and new-onset seizures in the other.

272 ected children that showed features of early-onset seizures, developmental delay, microcephaly, senso

273 r 3 in colostrum with a reduced risk of late-onset sepsis (HR: 0.63; 95% CI: 0.41, 0.97).

274 human milk oligosaccharides (HMOs) and late-onset sepsis in very-low-birth-weight infants, and to de

275 e entorhinal cortex were responsive to image onset, showing large deviations from baseline firing sho

276 at birth, but are at risk of developing late-onset SNHL.

277 iants as a cause of a progressive, pediatric-onset spastic movement disorder with variable clinical p

278 ization, and mortality observed during focal onset status epilepticus.

279 g with a second warming event with extreme R(onset) The epizootic lasted ~2 mo, extending beyond the

280 We show that, from birth to hearing onset, the auditory system relies on a consistent mechan

281 At 2 and 3 years before GA onset, they were associated with the presence of hypertr

282 l mechanisms encode temporal cues like voice-onset time (VOT), which distinguishes sounds like /b/ an

283 uli are presented closer to the eye movement onset time.

284 t varies with time from exposure and symptom onset to avoid being falsely reassured by negative test

285 hemic time, defined as the time from symptom onset to coronary reperfusion, was a pre-specified subgr

286 A delay from symptom onset to first injection of 30 days or more predicted hi

287 Times of symptom-onset-to-baseline-CT (hr) (median [interquartile range]:

288 Notably, the early-onset tumor formation observed in p53(5KR/5KR) and p53-n

289 duration variability, sleep onset, and sleep onset variability were assessed across 14 days close to

290 ulture-proven aspiration pneumonia and early-onset ventilator-associated pneumonia occurred in 54 pat

291 herapeutic profile as well as the resistance onset were characterized and a multiscale stochastic mat

292 /BxN model, organized insulitis and diabetes onset were unabated, despite a blocked anti-insulin vacc

293 , occurring within three months from disease onset, were collated to produce a DELTA-P score for each

294 , cells possess mechanisms to delay anaphase onset when Topo II is perturbed, providing additional ti

295 all had visited Gas Station X before illness onset, where 8 reported consuming a commercial cheese sa

296 2 days to a maximum of 6 weeks after symptom onset, whereas Mp DNA and antibodies persisted until 4 m

297 ed from NOD/ShiLtJ female mice after disease onset, whereas these drastic changes did not occur in ma

298 oclonus completely resolved within 2 days of onset, while in three cases, it persisted for 10 days or

299 very different curve shape and much earlier onset with bias.

300 isolation by 20% of cases 24 h after symptom onset would delay and flatten the outbreak trajectory, r