ライフサイエンスコーパス: open ring

1 in DnaB's C-terminal domain to trap it as an open ring.

2 ring; in 18%, as a nodule; and in 18%, as an open ring.

3 N-terminal domains (NTDs) forming a dynamic, open ring.

4 pical domain located at the top of the large open ring.

5 d more potent at A3 receptors than a related open-ring analogue.

6 mechanism, involving rounds of binding to an open ring and direct release into the bulk solution, can

7 s through exposed hydrophobic surfaces in an open ring and mediating productive folding in an encapsu

8 y cleaved C3-C4 bond, and thus containing an open ring C, as well as a compound containing a truncate

9 ansient threading of linear polymers through open ring chains stretching in flow.

10 ate that the solvent sensitivity of the ring-open/ring-closed equilibrium can be modified over a wide

11 athesis sequence involving ring closing-ring opening-ring closing and cross metathesis (RC-RO-RC-CM)

12 mechanism has been proposed involving a ring-opening-ring-closing cascade followed by a 1,3-indole mi

13 go facile acid-catalyzed or spontaneous ring-opening-ring-closing rearrangement to yield fused polyhe

14 A mechanism is proposed that involves a ring-opening/ring-closing (Dimroth) rearrangement.

15 e of the methylene aziridine promotes a ring-opening/ring-closing cascade that efficiently transfers

16 f the starting furoindole followed by a ring-opening/ring-closing event affording 2-spirocyclopentane

17 eochemistry of the observed products, a ring-opening/ring-closing mechanism is proposed and supported

18 Ring-opening/ring-closing metathesis on cyclobutene-containin

19 a second-generation approach, a tandem ring-opening/ring-closing metathesis reaction effected an ove

20 ntiomeric excess, as well as sigma-bond ring-opening/ring-closing transfiguration of low-strain heter

21 in N-aryl-2(1H)-pyrimidin-(thi)ones, a ring-opening/ring-closure process was contributing to the obs

22 ation of a nitrogen atom, followed by a ring-opening/ring-closure sequence mediated by (15)N-aspartat

23 We propose that Hsp90 functions in an open-ring configuration for client protein activation.

24 ernative sugars, congener structures or even open-ring configurations.

25 whereas the C-terminal regions modulate the open-ring conformation and RPA interaction.

26 at can adopt active closed-ring and inactive open-ring conformations.

27 7)H(7)) radical intermediate and exotic ring opening-ring contraction sequences terminated by atomic

28 re of the enzyme in complex with GlcA in its open ring form, in conjunction with mutagenesis studies,

29 lovastatin mixture used in this study is 80% open-ring form and 20% pro-drug, beta-lactone form.

30 We show that while the lovastatin open-ring form and pravastatin (a lovastatin analogue, 1

31 Additionally, we provide evidence that an open-ring form of the archaeal MCM homohexamer is loaded

32 We propose that the open ring formed by oligomeric ParR dimers with parC DNA

33 Our findings support the idea that an open ring forms the default conformational state of the

34 aled that ssDNA annealing is driven by RAD52 open rings in association with replication protein-A (RP

35 and pravastatin (a lovastatin analogue, 100% open ring) inhibit the HMG-CoA reductase enzyme, lovasta

36 An open ring is able to constrict, and rings repair from su

37 Open-ring lesions were periventricular or juxtacortical

38 Under neutral conditions, the open-ring merocyanine (MC(-)) exists to 48% and closes q

39 he closed-ring spiropyran (SP) moiety to the open-ring merocyanine (MC) form caused the quantum yield

40 mably TTC and TTT cis-trans isomers, for the open-ring merocyanine product, and discover a strong sol

41 d seco-rapamycin, which is the first in vivo open-ring metabolite of rapamycin that does not affect m

42 monitor the ability of Rho to switch between open-ring (RNA-loading) and closed-ring (RNA-translocati

43 The structure reveals an open ring-shaped architecture composed of Huntingtin, EF

44 ential roles in bacterial DNA replication by opening ring-shaped DnaB-family helicases and chaperonin

45 data show that Rho preferentially adopts an open-ring state in solution and that RNA and ATP are bot

46 an nucleate microtubules in vitro and has an open ring structure with a diameter of 25 nm.

47 g OBD and then transits through a gap in the open ring structure.

48 rn may also suggests a potential role for an open-ring structure for hexameric MCM and dynamic confor

49 , MCM2-7 spontaneously adopts a left-handed, open-ring structure.

50 ining ribose is found as a closed-ring or an open-ring sugar with a reactive C1' aldehyde group.

51 osed by the intermediate domains, but in the open rings, the pocket is accessible.

52 ubstrate protein in the central cavity of an open ring through exposed hydrophobic residues at the in

53 osed model suggests that the shift from the 'open-ring' to the 'open-spiral' and then the 'closed-spi

54 in GroEL binds non-native polypeptides in an open ring via hydrophobic contacts and then, after ATP a

55 onnative protein in the central cavity of an open ring, via hydrophobic surfaces of its apical domain

56 The AAA+ domains form an open ring without interactions between subunits and DNA.