ライフサイエンスコーパス: opening

1 ssociated with flower development and flower opening.

2 single-stranded DNA is exposed during origin opening.

3 solic constriction conduct ions upon channel opening.

4 g mitochondrial permeability transition pore opening.

5 1/2 mutant also developed cleft of the mouth opening.

6 g mitochondrial permeability transition pore opening.

7 charge movement, and its coupling to channel opening.

8 interactions that define regiochemical ring-opening.

9 ssDNA to the secondary site, to extend dsDNA opening.

10 r mitochondrial permeability transition pore opening.

11 steric clash between substituents upon ring-opening.

12 requencies during motor preparation for hand opening.

13 t was blocked by inhibition of TRPV4 channel opening.

14 omised by the specific mechanisms of FUS-BBB opening.

15 developed by merging C-H activation and ring opening.

16 oupling cyclic nucleotide binding to channel opening.

17 blue (585-660 nm) light beginning before eye-opening.

18 ligand binding site and culminating in pore opening.

19 arbon gain relative to a penalty of stomatal opening.

20 ectedly, also in low CO(2) -induced stomatal opening.

21 tion potential (AP) and are triggered by LCC openings.

22 and safety concerns owing to tight junction openings.

23 CI = 0.00-0.65) and moderate effect on mouth opening 0.60 (95%CI = 0.21-0.99) immediately after inter

24 resembling those used by insect navigators, opening a new avenue for the investigation of the neural

25 ze inhibitors to specific protein scaffolds, opening a new avenue to study localized kinase activity.

26 o higher coordination number and dimensions, opening a route toward a complete classification of amor

27 bled the synthesis of nucleic acids, perhaps opening a way into the RNA world.

28 le moiety into a carboxylic acid group, thus opening access to dicarboxylic acid derivatives.

29 substituted with S-, N-, and P-nucleophiles, opening access to various monofunctionalized sulfonated

30 (2+) influx and permeability transition pore opening after ischemic injury to reduce ongoing patholog

31 in a 0.70-mm annulus around Bruch's membrane opening after removal of large vessels.

32 Remarkably, mitochondria and their cristae openings align with those of neighboring inner segments.

33 nzothiadiazine 1,1-dioxides result in a ring opening along the N-N bond, followed by ring closure wit

34 sect to give pore space connected by 12-ring openings along all crystallographic directions.

35 provement of skill over LIM approaches, thus opening an avenue for environmental risk assessment rele

36 Single LGE caused a reduction in palpebral opening and an increase in capsaicin and menthol-evoked

37 species show an inverted pattern of stomatal opening and closing across the diel cycle, which conserv

38 e characteristic inverse pattern of stomatal opening and closing during CAM.

39 lls is dependent on the organized and timely opening and closing of chromatin.

40 common type of large motion, typified by the opening and closing of enzymes around their substrates.

41 are under axial strain in vivo and that the opening and closing of lymphatic valves leads to signifi

42 The opening and closing pressures of slits made in the bent

43 with decreased and increased Rac1 activities opening and closing, respectively, the silent synapse-me

44 and SINE2 play an important role in stomatal opening and closing.

45 hesions are both necessary for midline lumen opening and contribute to later maintenance of epithelia

46 The DNA helicase XPB plays a key role in DNA opening and coordinating damage incision by nucleases du

47 g pain was assessed by quantifying palpebral opening and evoked nociceptive responses after corneal a

48 a and 0.4-MPa FUS) consistently inducing BBB opening and extravascular transfection.

49 erocycles and acyclic compounds through ring-opening and fragmentation of the parent butenolide ring.

50 ng GABA(B) receptor activity promote channel opening and intensify oscillations.

51 nalysis revealed a reduced soft tissue wound opening and more rapid re-epithelialization with MaR1 de

52 e amount of C(2) H(2) and CO(2) through gate-opening and only negligible amount of C(2) H(4) .

53 Vaginal plate opening and ovipositor extrusion are thus controlled by

54 and thermodynamically favorable after enzyme opening and pyrophosphate release, and it appears to lim

55 also see occasional spontaneous lateral gate opening and sliding of the beta-strands at the gate inte

56 ) binding and voltage depolarization to pore opening and that shared Ca(2+) and voltage transduction

57 st bacterial chemotaxis through the stomatal opening and toward photosynthetic products within the le

58 ructures with released content and transient openings and closings of the fusion pores.

59 to a urinary bladder with a nephropore (exit opening) and a complex of diverticula, spread throughout

60 ylated imidazoles and rhodium-catalyzed ring-opening, and cyclization to N-difluoromethylated oxazole

61 tic arbors is already established before eye opening, and that these arbors primarily grow through le

62 Here we show theoretically that the opening angle of the conical interface varies on a logar

63 The force-coupled kinetics of ring-opening are probed by single molecule force spectroscopy

64 e extent to which red-light-induced stomatal opening arises from direct guard cell sensing of red lig

65 nduces endothelial blood-brain barrier (BBB) opening as well as the formation of a tight junction bar

66 ned here by NMR, this variant has no obvious openings as the ligand entrance and the gap cannot be wi

67 o radical chemistry, and acid-catalyzed ring-opening, as well as all other methods for the C-C bond c

68 estabilization occurred resulted in safe BBB openings, as shown by MR images and gross pathology.

69 XPB plays a key role in DNA opening at damage sites and coordinating damage incision

70 However, after eye opening at P14, Fam151b mutant eyes exhibit signs of ret

71 nes, a subset of which have unknown function opening avenues for exploration.

72 per understanding of the parasite's biology, opening avenues for the development of therapeutic inter

73 l complication characterized by an anomalous opening between the bladder and/or rectum and vagina res

74 ing the simultaneous prediction of both, the opening between the vocal folds and the symmetry axis, l

75 s federal, state and local governments begin opening businesses and relaxing shelter-in-place orders

76 ESCRT-III components accumulate at the opening but are not required for nuclear closure on thei

77 ly impairs high temperature-induced stomatal opening but has no effect on the induction of heat-sensi

78 eosome-wrapped DNA to perform this chromatin opening by mechanisms that remain incompletely understoo

79 osphorylation of TRPC1 essential for channel opening by phosphatidylinositol 4,5-bisphosphate (PIP(2)

80 sphorylate TRPC1 proteins to promote channel opening by phosphatidylinositol 4,5-bisphosphate (PIP(2)

81 PKCdelta activity is obligatory for channel opening by PIP(2) , the probable activating ligand.

82 A novel palladium-catalyzed ring opening carbonylative lactonization of readily available

83 ttached to the salivarium and their possible opening /closing of the salivarium, with a plausible exp

84 Opening, closing, and translation along the DNA of the S

85 Backbone HDX is mediated by opening/closing (unfolding/refolding) fluctuations.

86 the tubes kept straight when perforated, the opening/closing pressure ranged from 5 to 25 cmH(2)O.

87 exhibited a canonical scenario, where local opening/closing was associated with positive DeltaH and

88 anates are introduced as comonomers for ring-opening copolymerization (ROCOP) with epoxides.

89 protic CTAs in reversible-deactivation ring-opening copolymerizations (RD-ROCOP), yet the predominan

90 500 and 750 mum from the scleral spur: angle opening distance (AOD), trabecular iris space area (TISA

91 th, and dependent variables, including angle opening distance, were measured in 1 randomly selected e

92 41) were the strongest determinants of angle opening distance.

93 ch may render robustness in dealing with and opening diverse lesions.

94 ity of current water-treatment processes and opening doors for new applications of membrane technolog

95 articipants were attempting to generate hand opening either supported on a table or when lifting agai

96 stant suction pressure; the trap door's fast opening ensures effectively instantaneous onset of sucti

97 itary conductance accompanied by spontaneous opening events in the absence of extracellular glycine.

98 role of multisensory processing, while also opening exciting opportunities to facilitate early learn

99 constraints and prime the channel for rapid opening, facilitating fast synaptic transmission.

100 lace in a two-step process: barrierless cage opening followed by Coulomb repulsion-driven fragmentati

101 ampal parenchymal enhancement indicating BBB opening, followed by BBB closure within 24 h.

102 etermine the thermodynamics of the base pair opening for MN4.

103 It becomes accessible upon pocket opening for selective covalent attachment of electrophil

104 unding of the wheat leaf provides additional openings for fungal entry.

105 and Valsalva grafts had significantly higher opening forces versus controls (P<0.01).

106 Relative cusp opening forces were similar between SG, Uni-Graft, and c

107 is a common birth defect where the urethral opening forms on the ventral side of the penis.

108 ith its homologs that cannot trigger channel opening has not been made so far.

109 flap-like structure that overlies the mouth opening in almost all extant representatives-from an anc

110 last movement, leaf flattening, and stomatal opening in Arabidopsis.

111 The same domain is involved in chromatin opening in early mouse embryos for normal development.

112 s in improving swallowing function and mouth opening in HNC patients undergoing multimodal treatment.

113 e light spectrum, red light induces stomatal opening in intact leaves.

114 PK23 were found to exhibit impaired stomatal opening in response to blue light but no deficits in oth

115 A, we detect and characterize TL closing and opening in solution.

116 ic neuroinflammatory tolerance" in which BBB opening in the resting state is sufficient to stimulate

117 hosteric and allosteric agonists appeared as openings in quick succession (bursts) that showed no lig

118 te cells can be produced in vitro from iPSC, opening interesting avenues for muscular dystrophy cell

119 cesses can be used to safely advance FUS-BBB opening into a wider range of clinical applications.

120 he hypothesis that STIM1-mediated Orai1 pore opening is accompanied by a global conformational change

121 The iris-like channel opening is accompanied by an alpha-to-pai helical transi

122 Channel opening is also associated with changes in occupancy of

123 range of pressure for efficient and safe BBB opening is very narrow.

124 rt of such a mechanism were lacking and how 'opening' is brought about remained unclear.

125 ither betaB-betaD or helix 2 can generate an opening large enough for ligands to enter the protein ca

126 rly challenging because of the small natural openings leading from the sinuses that can be further ob

127 recipient, whose bladder above the ureteral opening level was removed.

128 action resembles that of endogenous channel-opening lipids and opens up an avenue for the developmen

129 cyclopropanols, including base-mediated ring-opening, metal-catalyzed C-C insertions and eliminations

130 Photo-redox mediated ring-opening metathesis polymerization (photo-ROMP) is an eme

131 r, we report the surprisingly effective ring-opening metathesis polymerization (ROMP) of cyclic enol

132 ctional block copolymers synthesized by ring-opening metathesis polymerization (ROMP) that can insert

133 ntrol and functional group tolerance of ring-opening metathesis polymerization (ROMP).

134 s to participate in cascade alternating ring-opening metathesis polymerization through their efficien

135 Bruch membrane opening-minimum rim width (BMO-MRW) assessment offers a

136 ing by minimum rim width at Bruch's membrane opening (MRW-BMO).

137 plus glibenclamide, an antagonist of K(ATP) opening (NaHS Glib), and Glib alone (Glib).

138 number of detrimental effects: for example, opening nearby K(+) channels to weaken synaptic efficacy

139 Nanotechnology-based smart sensors are opening new avenues for early and rapid detection of suc

140 hip sensing platform with unique properties, opening new avenues for highly integrated sensing device

141 lying movement-initiation and -cancellation, opening new avenues for the study of motor control in he

142 promising targets for CM adjunctive therapy, opening new avenues for the treatment of this deadly dis

143 nce of the main group elements in catalysis, opening new avenues in synthetic chemistry.

144 paper represents an important first step in opening new avenues of research by leveraging the power

145 ieved in reversible transfer reactions, thus opening new horizons for their synthetic applications.

146 modifications in modulating brain functions, opening new insights into the molecular basis of neurolo

147 but highly significant for the active state, opening new opportunities to tune potency and agonism of

148 applications in Quantum Information Science, opening new perspectives for the scalability of quantum

149 e recognition of lysine-containing peptides, opening new perspectives in the field of peptide sensing

150 ites associated with depression, potentially opening new prevention or treatment avenues for depressi

151 hts on nanocavity-enhanced electrochemistry, opening new routes for biochemical detection, water moni

152 Advances in genomics are opening new windows into the biology of schizophrenia.

153 portant sources of microbial DNA in the CNS, opening novel opportunities for therapeutic intervention

154 mal-myeloid unit of the distal lung, thereby opening numerous new avenues to study lung development,

155 Substate openings O(1)', O(2)', and O(3)', between the fully open

156 mannitol induces osmotic blood-brain barrier opening (OBBBO) and that method has been used for decade

157 via unprecedented Ph(3)P-I(2) mediated ring-opening of 1,3-dihydro-1H-benzimidazol-2-ones with secon

158 of Ti imidos with nitriles and alkynes, ring opening of 2-imino-2H-azirines, or direct metalation of

159 H(2)(18)O to elucidate the mechanism of ring opening of 7(*+) and trapping of the resulting distonic

160 y filter to enhance calcium permeability and opening of a canonical gate at the cytoplasmic end of th

161 intervention, such as queen clipping and the opening of a hive, causes strong interferences with impo

162 Brief exposure to ATP induces the opening of a nonselective cation channel; while repeated

163 covered electronic stabilization through the opening of a shell-closing gap at the top of the occupie

164 Emerging methods for enantioselective ring opening of acceptor- or donor-only cyclopropanes are the

165 While most microfluidic systems use the opening of additional parts of the channel to allow the

166 Opening of both cyclopropane rings in 2'-aryl-1,1'-bicyc

167 resolutions: first, an atroposelective ring opening of Bringmann-type lactones produces a product wi

168 ond messenger NAADP and thereby promotes the opening of Ca(2+) -permeable two-pore channels (TPCs).

169 ation prompted an unprecedented delay in the opening of California's Dungeness crab fishery that inad

170 e binding of transcription factors and local opening of chromatin.

171 This study shows that opening of connexin 43 (Cx43) hemichannels leading to th

172 ) that are required for the CO(2) -dependent opening of Cx26 hemichannels.

173 A nucleophilic retro-Claisen ring-opening of donor-acceptor cyclobutenes, formed with high

174 A straightforward method for ring opening of donor-acceptor cyclopropanes with trimethylsi

175 each component that permits this sequential opening of Env remains unknown.

176 tropic glutamate receptor signaling triggers opening of GluD2.

177 behaviour with slow magnetic relaxation and opening of hysteresis loops was observed.

178 ancing and uncertainty about the complete re-opening of laboratories and campuses, there is a pressin

179 ) S confers embryonic cardiac protection via opening of myocardial K(ATP) channels and not via increa

180 compromised host-symbiont state and (ii) the opening of niche space for potential pathogens during th

181 Caspase-mediated opening of pannexin 1 channels at the plasma membrane fa

182 sults reveal that the rate constant for ring opening of radical cations derived from 1'-methyl-3',4'-

183 ds to LL HC hyperpolarization because of the opening of small-conductance Ca(2+)-activated potassium

184 Opening of stomata in plants with crassulacean acid meta

185 including the activation of Rubisco and the opening of stomata, whereas transitions from high to low

186 Our results show that facilitating opening of syntaxin enhances exocytosis in a wide range

187 cillin-binding protein (PBP)2a, resulting in opening of the active site, whereby the beta-lactam anti

188 nt a model that is based on a time-dependent opening of the BBB for nanoparticles, followed by a rapi

189 Once closed, re-opening of the canal occurred in a wave, triggered by te

190 Rate-determining opening of the chelate by an ancillary ligand followed b

191 f structural changes which terminate with an opening of the complex into two separate domains, one of

192 uces a closing of the D1-D3 interface and an opening of the D1-D2 interface.

193 n by changing climatic conditions and by the opening of the Drake Passage and associated intensificat

194 Neutrophil extravasation requires opening of the endothelial barrier but does not necessar

195 nt laryngeal nerve following the progressive opening of the esophageal prosthesis.

196 taneous nerve got injured during the fascial opening of the extensor compartment.

197 The guest diffusion occurs by opening of the flexible window formed by four pyrazines.

198 e often generated from [1.1.1]propellane via opening of the internal C-C bond through the addition of

199 ment of a noncanonical toggle switch and the opening of the intracellular crevice for G protein coupl

200 ivation mechanism, which proceeds through an opening of the intracellular region allosterically elici

201 rst opens, followed by DNA binding, inducing opening of the loader to release autoinhibition.

202 sformation between these two phases involves opening of the P(3) ring at the base of the P(4)Se(3) mo

203 yo-electron microscopy structures reveal the opening of the RagB lid and thus provide direct evidence

204 ese results reconcile competing ideas on the opening of the rift system by highlighting differences i

205 Release from chromatin involves opening of the ring at the Smc3-Scc1 interface in a reac

206 e (ATP) analogs, which is expected to induce opening of the sliding clamp.

207 The alternate opening of the stem-loop structure of H(1) and H(2)-AuNP

208 aled through either of two discrete actions: opening of the vaginal plates to allow copulation, or ex

209 PTP (permeability transition pore) and that opening of this pore leads to necroptosis, a regulated f

210 rst examples of selective and regiodivergent opening of unsymmetrical phenonium ions with chloride io

211 osis in alpha-cells is tightly linked to the opening of voltage-gated P/Q-type Ca(2+) channels, the a

212 The static dimensions of the pore openings of both materials are too small to admit either

213 the most at risk, and factors including the openings of some schools, are considered.

214 (op/op) mice in which a mutation mimics the "opening" of ClC-2 by GlialCAM.

215 e of the secondary effects caused by FUS-BBB opening on brain physiology, identify areas that remain

216 he parameters influencing the lipid membrane opening/permeability, the electrochemical detection of s

217 ons of Orai subunits as a core element of an opening-permissive Orai channel architecture.

218 s in mESCs depending on its receptor dosage, opening perspectives for balancing self-renewal and line

219 h the nucleosome contribute to the chromatin-opening phenomenon.

220 le mutants, in correlation with the stomatal opening phenotype.

221 Reported here is the first aqueous ring-opening polymerization (ROP) of N-carboxyanhydrides (NCA

222 r, dioxolane (DOL), is known to undergo ring-opening polymerization inside electrochemical cells to f

223 le polymers are prepared via an anionic ring-opening polymerization of a bicyclic beta-lactam sugar m

224 alongside the synthetic advances in the ring opening polymerization of alpha-amino acid N-carboxyanhy

225 ds, no microplates or stirring was required, opening possibilities for field analysis since the multi

226 rt a model in which TARK1 regulates stomatal opening postelicitation.

227 ), seizures (p=.0005), elevated intracranial opening pressure (p=.03), higher CSF white cells (p=.007

228 ssure gradient at which the tube leaked dye (opening pressure) and ceased to leak (closing pressure),

229 d by compliance at low PEEP (or above airway opening pressure) estimated the recruited volume by PEEP

230 age were less often female and had lower CSF opening pressure, fewer headaches, a higher chance of in

231 eceptor to closed intermediate states before opening (priming).

232 The opening process reduces S1 contacts and unshields the tr

233 e covered in reactions involving direct ring-opening processes or transformations through nonisolable

234 nally, the structure of the anticipated ring-opening product, dibenzosuberenone, bearing a beta-amino

235 econd timescale; we show that TL closing and opening provides a checkpoint for NTP complementarity, N

236 cy, and the inverse relationship to the rung-opening rate coefficient.

237 ectrolytes are in situ polymerized by a ring-opening reaction in the presence of aluminum fluoride (A

238 aiyama aldol reaction, Nicolaou-type epoxide opening reaction, stereoselective Corey-Chaykovsky-type

239 dopsis mutants, and discovered that stomatal opening response to red light is correlated with a decre

240 This spontaneous gap opening shows pronounced hysteresis and other signatures

241 alpha1S270T mutation is likely to affect the opening step in GlyR activation.

242 nts involved in blue light-mediated stomatal opening, suggesting cross talk between light and tempera

243 Here, we investigate closure of the NE opening surrounding the meiotic spindle in C. elegans oo

244 In thoracoabdominal NRP opening the aortic arch vessels to atmosphere allows col

245 d inhibits GE-ERalpha(vlVMH) neurons through opening the ATP-sensitive potassium channel.

246 ctor facilitates transcription initiation by opening the DNA strands around the transcription start s

247 thermal conditions at high temperature, thus opening the door for the isolation of additional titaniu

248 base pairs (unnatural base pairs, UBPs) are opening the door to a new research area, xenobiology, an

249 xts that can be quantitatively investigated, opening the door to a new understanding of natural behav

250 derlie distinct D2R-dependent behaviors, and opening the door to more targeted therapeutics.

251 ed and tracked clinical outcome, potentially opening the door to treatment optimization.

252 clinical, research, and industrial interest, opening the microfluidic droplet technologies for adapta

253 low energy pathway for ligand dissociation, opening the needed coordination site.

254 catalytic activities found in metazoan CCDs, opening the possibility of modifying their activity thro

255 generate spatially variable acoustic fields, opening the possibility that the channel geometry can be

256 ation of olive oil was corroborated clearly, opening the potential to investigate adulteration of oth

257 on neuronal function (GABA-ergic dynamics), opening the way for psychopharmacological studies in hea

258 one coupled to an appropriate optical setup, opening the way to simple and inexpensive point-of-care

259 late instantaneous carbon gain from stomatal opening (the gain function).

260 efore conclude that CIPK23 promotes stomatal opening through activation of K(+) (in) channels most li

261 urrounding the diapedesis pore, keeping this opening tightly closed around the transmigrating neutrop

262 Integrating flower opening time during cooler hours with increased pollen a

263 nd adenosine monophosphate), results in ring opening to linear tetraphosphates bearing one nucleophil

264 y effects is becoming vital now that FUS-BBB opening treatments have entered clinical trials.

265 and we show that one cycle of TL closing and opening typically occurs in each nucleotide addition cyc

266 sted a specific function of UNC-13/Munc13 in opening UNC-64/ syntaxin.

267 ons, highlighting their interpretability and opening up a way to generate similarity estimates from o

268 d copy number-determined clonal lineages and opening up an important form of clonal analysis in cance

269 new human-yeast complementation pairs, thus opening up avenues to further functionally characterize

270 sense analytes ranging from ions to enzymes, opening up diverse possibilities for (19) F MR based bio

271 This is opening up new opportunities to decipher words written m

272 cal determinants of LRRK2 neurodegeneration, opening up possibilities for future therapeutic interven

273 ological recognition sites and drug targets, opening up possibilities for pharmaceutical and biologic

274 only by removing DNA methylation but also by opening up previously CpG methylated regions for PRC2 re

275 gated virus-induced symptoms in rice plants, opening up the development of Wolbachia-based strategies

276 can now be obtained in a matter of seconds, opening up the possibility of high-throughput screening

277 measurements in the proximal lumbar plexus, opening up the possibility of studying a broad spectrum

278 bits AMPARs in an activity-dependent manner, opening up this pathway as a means to pharmacologically

279 afts except SG had significantly higher cusp opening velocities versus native roots (P<0.01 for each)

280 in fine tuning the granulocytic production, opening venues for clinical intervention that require en

281 by lesion discrimination relied on efficient opening versus diffusion.

282 yzes different reactions (styrene oxide ring-opening, vesidryl synthesis, Friedel-Crafts alkylation,

283 5, unexpectedly results in synergic THF ring-opening via a radical mechanism.

284 The average opening was 95% of the targeted FUS volume, which corres

285 bulk materials and a highly desirable trait, opening ways to design semiconducting materials based on

286 To quantify the effects of infusion on BBB opening, we calculated the MRI contrast enhancement rate

287 ory speech envelope and lip movements (mouth opening) when listening to a spoken story without visual

288 tions behave like pressure-sensitive valves, opening whenever intraluminal pressure increases above a

289 Low concentrations of CO(2) cause stomatal opening, whereas [CO(2) ] elevation leads to stomatal cl

290 We found that homes that reported opening windows more often were strongly associated with

291 g radical cation undergoes cyclopropane ring opening with a rate constant of only 4.1 x 10(4) s(-1),

292 ion increases dramatically just prior to eye opening with a time course closely correlated with that

293 B because of a closer match in the degree of opening with AimB size, suggesting coevolution of AimB w

294 cs simulations further correlated Omega-loop opening with catalytic activity.

295 uitable substrates for enantioselective ring opening with CsF and a chiral bis-urea catalyst.

296 afety, feasibility, and reversibility of BBB opening with FUS treatment of the hippocampus and entorh

297 enabling diamination by regioselective ring-opening with primary or secondary amines.

298 nitrene dissociation toward heterolytic ring opening with the arylboronic acid; the resulting dipolar

299 ve the complex in a conformation before PCNA opening, with the clamp loader ATPase modules forming an

300 es the channel structure and impairs channel opening without altering cilia localization and channel