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1 findings of patients with acute UGIB who use opium.
2 citly use opiates, of whom 4 million use raw opium.
3 rising from compounds that are common in raw opium.
4 gnificantly higher in patients who used oral opium (40% vs. 12%; P-value = 0.007).
5 g poisoning, which included methadone 43.8%, opium 41.4%, amphetamine 8.2%, cannabis 3.3%, buprenorph
6 l EDs or GI clinics if a positive history of opium abuse exists.
7         These findings align with studies of opium addicts.
8                   RNA aptamers that bind the opium alkaloid codeine were generated using an iterative
9  varieties are used for both, pharmaceutical opium alkaloid generation and poppy seed production for
10            We have previously discovered the opium alkaloid noscapine as a microtubule interacting ag
11            We have previously identified the opium alkaloid noscapine as a microtubule interacting ag
12         Poppy seeds can be contaminated with opium alkaloid-containing latex, e.g. during harvesting.
13 rward method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine,
14 imple and classical reactions to address the opium alkaloids and will serve as an efficient route to
15  in food and highlight also considering some opium alkaloids in current legislation.
16           So far, risk assessments regarding opium alkaloids in poppy seeds were mainly based on the
17                                              Opium alkaloids such as morphine and thebaine occur in t
18 y based on the morphine level, whereas other opium alkaloids thereunder thebaine could not be finally
19  heck cyclization to access the ABCE ring of opium alkaloids with the required stereocenters in one p
20 vine derivatives [buprenorphine] and natural opium alkaloids).
21 lkaloids, such as pyrrolizidine, tropane and opium alkaloids, have stressed the need to monitor their
22  recent years, poppy seed contamination with opium alkaloids, including thebaine, gave repeatedly rea
23 actors were identified for tobacco, alcohol, opium and germline variants, with modest impacts on muta
24 re to polycyclic aromatic hydrocarbons (from opium and indoor air pollution), and nutrient-deficient
25 nificantly associated with comorbid cocaine, opium, and nicotine dependence.
26  opium still seems to persist in the Iranian opium black market.
27                                 Ingestion of opium (but not smoking opium) was associated with brain
28       Substitution of this lead-contaminated opium by Opioid Maintenance Therapy (OMT)-prescribed opi
29 association with the female sex (P < 0.001), opium consumption (P < 0.001), and history of MI (P = 0.
30 eased odds ratio of LSD were associated with opium consumption (P = 0.046) and thyroid dysfunction (P
31             Morphine, first characterized in opium from the poppy Papaver somniferum, is one of the s
32                                              Opium is one of the world's oldest drugs, and its deriva
33                             An alkaloid from opium, noscapine, is used as an antitussive drug and has
34    Three and two cases, due to methadone and opium poisoning died.
35                                   Farming of opium poppies remains the sole source of these essential
36                     Just over 100 years ago, opium poppies were still grown on the Cambridgeshire fen
37 ecarboxylase DNA fragment was generated from opium poppy (Papaver somniferum L.) genomic DNA by the P
38                                          The opium poppy (Papaver somniferum L.) is one of the oldest
39 ous end-joining genome repair, the 4'OMT2 in opium poppy (Papaver somniferum L.), a gene which regula
40 ne silencing, we show that FUL-like genes in opium poppy (Papaver somniferum) and California poppy (E
41 is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of th
42 lation and functional characterization of an opium poppy (Papaver somniferum) cDNA encoding DBOX, a f
43 soquinoline alkaloid (BIA) transporters from opium poppy (Papaver somniferum) have not been reported.
44 ally distinct N-methyltransferase (NMT) from opium poppy (Papaver somniferum) that primarily accepts
45 is of codeine and morphine, respectively, in opium poppy (Papaver somniferum).
46 fic localization of morphine biosynthesis in opium poppy (Papaver somniferum).
47 compounds isolated from a single source, the opium poppy (Papaver somniferum).
48                                              Opium poppy accumulates copious amounts of several benzy
49                 Morphinan alkaloids from the opium poppy are used for pain relief.
50 ss of benzylisoquinoline alkaloids (BIAs) in opium poppy as the resulting bi-modular protein performs
51  transcript and metabolite profiles of eight opium poppy chemotypes revealed four cytochrome P-450s,
52 m cDNA libraries and latex extracts of eight opium poppy cultivars displaying different alkaloid prof
53   Stem cDNA libraries from each of the eight opium poppy cultivars were subjected to 454 pyrosequenci
54     The synthetic pathway of morphine in the opium poppy has been elucidated.
55 vel BIA biosynthetic and regulatory genes in opium poppy has been established based on the differenti
56    However, the biosynthesis of noscapine in opium poppy has not been established.
57                  BUP1 is highly expressed in opium poppy latex and is localized to the plasma membran
58 es were found during random sequencing of an opium poppy latex cDNA library.
59                                              Opium poppy mosaic virus (OPMV) is a recently discovered
60        SOMT transcripts were detected in all opium poppy organs but were most abundant in aerial orga
61     Since the isolation of morphine from the opium poppy over 200 years ago, the molecular basis of o
62  potential anticancer drug isolated from the opium poppy Papaver somniferum, and genes encoding enzym
63 aridine, the known morphine precursor in the opium poppy plant.
64                                              Opium poppy produces a wide variety of benzylisoquinolin
65 (RNMT) using virus-induced gene silencing in opium poppy resulted in a significant decrease in magnof
66 sanguinarine, and papaverine accumulation in opium poppy roots in support of DBOX as a multifunctiona
67                        A query of translated opium poppy stem transcriptome databases using berberine
68 xpected, CYP82Y1 was abundantly expressed in opium poppy stems where noscapine accumulation is highes
69      Noscapine is an antitumor alkaloid from opium poppy that binds tubulin, arrests metaphase, and i
70 equence shares extensive identity with other opium poppy tyrosine/3,4-dihydroxyphenylalanine decarbox
71 as isolated that encodes a new member of the opium poppy tyrosine/3,4-dihydroxyphenylalanine decarbox
72             Morphine is an alkaloid from the opium poppy used to treat pain.
73 m the basal eudicot, Papaver somniferum (the opium poppy), and demonstrate a role for the gene in pat
74 s in a new model system, Papaver somniferum (opium poppy).
75 turase (PapsPDS) gene in Papaver somniferum (opium poppy).
76               The alkaloid-rich latex of the opium poppy, Papaver somniferum L., is valued as a sourc
77                                           In opium poppy, the antepenultimate and final steps in morp
78                            Interestingly, in opium poppy, these genes also control flowering time and
79 bclass of opioids naturally derived from the opium poppy.
80  involved in opiate alkaloid biosynthesis in opium poppy.
81 endemically and uniquely in the latex of the opium poppy.
82 mitted step in the formation of noscapine in opium poppy.
83 lar localization of morphine biosynthesis in opium poppy.
84 guinarine and certain rhoeadine alkaloids in opium poppy.
85 mes in the biosynthesis of both alkaloids in opium poppy.
86 is in the roots and germinating seedlings of opium poppy.
87 t homology with the major latex protein from opium-poppy.
88 re should allow more efficient production of opium products and may be easily modified for large-scal
89  first detailed ion mobility study on seized opium samples.
90 ies of this instrument using four samples of opium seized by the Canada Border Services Agency (CBSA)
91                                              Opium smoking (HR 1.85; 95% CI 1.18-2.90), drinking hot
92 ional exposures as before, lead-contaminated opium still seems to persist in the Iranian opium black
93  Opioid Maintenance Therapy (OMT)-prescribed opium tincture is recommended.
94 god of dreams could not have dreamt that his opium tincture would be both a gift and a burden to huma
95 ontrolling for age, sex, tobacco smoking and opium usage history, alcohol consumption, and socioecono
96 ic data of 50 consecutive patients with oral opium use and 50 consecutive patients without any opium
97 eview to investigate the association between opium use and cancer incidence and mortality.
98  investigate the association between regular opium use and cancer incidence.
99 es that collect detailed data about lifetime opium use and control for a broad range of potential con
100 sponding 95% CIs for the association between opium use and different cancer types.
101 bserved in 46% and 16% of patients with oral opium use and without opium use, respectively (P-value =
102 ion between acute gastric/duodenal ulcer and opium use has been previously proposed; however, there i
103                                              Opium use was associated with an increased risk of cance
104                               Only high-dose opium use was associated with pancreatic cancer (2.66, 1
105                                    The daily opium use was more than 2.75 g.
106  use and 50 consecutive patients without any opium use who were admitted for UGIB were recorded.
107 n participant demographics, diet, lifestyle, opium use, and different exposures were collected upon e
108  of patients with oral opium use and without opium use, respectively (P-value = 0.001).
109 ncluding cigarette and waterpipe smoking and opium use.
110 s in GIB are potential complications of oral opium use.
111 s, and alcohol, cigarettes, water pipes, and opium use.
112 BLLs were significantly correlated with oral opium use/abuse, history of addiction for over the prece
113 phageal ulcers were also more common in oral opium users (30%) than non-users (8%) with UGIB (P-value
114                                              Opium users have a significantly higher risk of developi
115                                       Use of opium was associated with an increased risk of developin
116            For site-specific cancers, use of opium was associated with an increased risk of developin
117          Ingestion of opium (but not smoking opium) was associated with brain (2.15, 1.00-4.63) and l
118 , a benzylisoquinoline alkaloid derived from opium, was recently reported to exhibit activity against
119 ght control, and abstinence from smoking and opium) were delivered by the PolyIran field visit team a
120 he interaction effect of smoking tobacco and opium with the DMFT score on the risk of developing HNSC
121 ng the interaction of cocaine, nicotine, and opium with these variants.

 
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