ライフサイエンスコーパス: optic lobe

1 hyperinflated cerebrum and ventrally shifted optic lobes).

2 s required for accurate axon guidance in the optic lobe.

3 n a single column to a specific layer of the optic lobe.

4 in clones of cells in the Drosophila larval optic lobe.

5 NS from rat cerebellar mossy fiber and squid optic lobe.

6 adjacent cell populations in the developing optic lobe.

7 res, the larval eye (Bolwig's organ) and the optic lobe.

8 pound eye connect to specific targets in the optic lobe.

9 t axons to targets in distinct layers of the optic lobe.

10 ivity and for spatial positioning within the optic lobe.

11 is restricted to the lateral neurons of the optic lobe.

12 s in a single EM dataset covering the entire optic lobe.

13 c connections with their target cells in the optic lobe.

14 RNA and protein expression in the developing optic lobe.

15 he developing photoreceptor cells and in the optic lobe.

16 inct, reproducible numbers-from 5 to 800 per optic lobe.

17 tiation are still unclear, especially in the optic lobe.

18 atomical and spatial organization within the optic lobe.

19 d a detailed laminar organization within the optic lobe.

20 ent during the development of the Drosophila optic lobe.

21 es the central brain, ventral nerve cord and optic lobe.

22 and vertically converged organization of the optic lobe.

23 ty object motion detection in the Drosophila optic lobe.

24 minently in the mammalian retina and the fly optic lobe.

25 be correctly aligned with the neurons of the optic lobe.

26 each their retinotopic position in the adult optic lobe.

27 ons that populate the different parts of the optic lobe.

28 la plate tangential cells (LPTCs) in the fly optic lobe.

29 fields in the lobula and lobula plate of the optic lobes.

30 as preceded by petechial hemorrhaging in the optic lobes.

31 ated by comparisons of insect and crustacean optic lobes.

32 ons adjacent to the accessory medulla of the optic lobes.

33 ra receive substantial direct input from the optic lobes.

34 ride channels have been identified in insect optic lobes.

35 ds its projection to different layers of the optic lobes.

36 ventional myosins is present in axoplasm and optic lobes.

37 centrifugal neurons from the midbrain to the optic lobes.

38 s generally correlates well with that of the optic lobes.

39 similar expression patterns in the eyes and optic lobes.

40 localizes to specific synaptic layers in the optic lobes.

41 pheres and between the central brain and the optic lobes.

42 ntral brain regions receiving input from the optic lobes.

43 vestigate the role of Black and Ebony in fly optic lobes.

44 l neurons from the medulla of the dorsal eye optic lobes.

45 ypes in the motion pathways of the fruit fly optic lobe(1-5) but with unknown parameters for the sing

46 e large neuronal diversity of the Drosophila optic lobe(3) and its connectome(4-6) are almost complet

47 entified 32 brain lobes, including two large optic lobes (75% the total volume of the brain), chromat

48 In the Drosophila optic lobes, 800 retinotopically organized columns in th

49 In the fly optic lobe, ~800 highly stereotypical columnar microcirc

50 n center (tOPC) of the developing Drosophila optic lobes, a unique temporal series of transcription f

51 In the optic lobe, ACh was also found to be localised in discre

52 nt, secretion of Beaten path by cells of the optic lobes allows the Fasciclin II-expressing larval vi

53 In the optic lobe, an alternative expansion strategy involves s

54 e this emerging approach with the Drosophila optic lobe, analysing its structure to predict that thre

55 ponents have multiple motor units within the optic lobe and are organized in a mosaic manner.

56 jection neurons at the interface between the optic lobe and central brain form a set of discrete chan

57 vity with 'boundary types' that straddle the optic lobe and central brain is also quantified.

58 d in a mosaic pattern, where the avian-grade optic lobe and cerebellum evolved first among non-aviala

59 an extremely large wulst as well as a small optic lobe and distinct occipital sinus.

60 stem, we generated CadN mutant clones in the optic lobe and examined the target-selection of genetica

61 components of the nervous system lies in the optic lobe and is readily assayed by its effect on downs

62 naling results in an almost total absence of optic lobe and larval eye, as well as severe reduction o

63 We found that the optic lobe and larval photoreceptors share the same orig

64 However, the functional organization of the optic lobe and neural control of the various body patter

65 from the eye disc grow their axons into the optic lobe and secrete Hedgehog (Hh) to induce the lamin

66 that large APs originate in the ipsilateral optic lobe and small APs in the contralateral.

67 ponents may have multiple motor units in the optic lobe and that these are organized in a mosaic mann

68 icited by stimulating different parts of the optic lobe and that various subsets of these components

69 ion Detector (STMD) neurons are found in the optic lobes and are believed to be presynaptic to Target

70 of central brain neurons that innervate the optic lobes and are required for eclosion.

71 that strongly and positively covary with the optic lobes and have increased volume of the Kenyon cell

72 on analyses of neural tissue (central brain, optic lobes and ommatidia) across development in two sym

73 nvolved in visual processing, especially the optic lobes and parts of the mushroom bodies receiving v

74 owed their projections to other areas in the optic lobes and the central brain.

75 ts including six distinct tracts between the optic lobes and the cerebrum.

76 a small, neck-like constriction between the optic lobes and the rest of the brain.

77 vely for electrophysiological studies of the optic lobes and their central projections.

78 head, including dorsal pouch epithelium, the optic lobe, and head sensory organs, including Bolwig's

79 ormal projections to the medulla part of the optic lobe, and not to the lamina where outer PRCs proje

80 lobe, downregulation of proliferation in the optic lobe, and separation of R7 from R8 in the medulla

81 ncluding the central body, the lobula of the optic lobe, and the tritocerebrum.

82 sis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a t

83 neurons project into the lobula plate of the optic lobe, and two of these cells extend axons ipsi- an

84 of male-specific olfactory glomeruli, 3) the optic lobes, and 4) multimodal interneurons that origina

85 with the arrival of retinal afferents at the optic lobes, and cell death in the lamina cortex begins

86 to have dopamine levels, the central brain, optic lobes, and posterior superiormedial protocerebrum

87 e known neuronal diversity of the Drosophila optic lobes, and serve as a paradigm to understand brain

88 s between brain regions, new pathways in the optic lobes, and spatially segregated projections to cen

89 Cell proliferation within the optic lobe anlagen is dependent on ecdysteroids during m

90 and Cad74A, are expressed in the epithelial optic lobe anlagen, which matches the widespread epithel

91 so found in brain regions without AmTAR1-IR (optic lobes, antennal lobes), indicating that other tyra

92 morphosis, when postsynaptic elements in the optic lobe are being selected.

93 control of the various body patterns by the optic lobe are largely unknown.

94 In insects, visual neurons in the optic lobe are modulated by locomotion, but the degree t

95 Neurons of the optic lobe are produced during the larval period from tw

96 pand their head capsule so that the eyes and optic lobes are displaced at the ends of stalks that ext

97 Our findings present the Drosophila optic lobe as a useful model to analyze the key signalin

98 reveals that tll functions to drive cells to optic lobe as opposed to Bolwig's organ fate.

99 larval visual organ cells to detach from the optic lobes as a cohesive cell cluster.

100 orsal medial portion of the brain and in the optic lobe, as well as neuroblast-specific repression ar

101 lete the list of cell types intrinsic to the optic lobe, as well as the rules governing their connect

102 cells, differentiated cells of the brain and optic lobes, as well as sensory systems of the head.

103 ly, mir-8 is expressed in a subpopulation of optic-lobe-associated cortex glia that extend processes

104 xon tracts, along with the mushroom body and optic lobe, both of which are also FasII-positive, repre

105 nge of tissues including the embryonic head, optic lobes, brain, central nervous system as well as th

106 ution of per gene products in M. sexta eyes, optic lobes, brains, and retrocerebral complexes.

107 resence of neuroglioblasts in the developing optic lobes but did not indicate the production of glia

108 opurifies with p235 shows that it is a squid optic lobe calcium-binding protein, which is more simila

109 opamine-like immunoreactive processes to the optic lobes, circumscribed regions of the protocerebrum

110 xylin and eosin-stained sections through the optic lobe confirmed the identities of the positively im

111 By contrast, the adult optic lobe contains a diverse repertoire of neuronal and

112 rts the functional analogy of the cephalopod optic lobe cortex and the vertebrate inner retina in vis

113 Optic lobe cortical axons extend from dorsal and ventral

114 lia is accompanied by extensive apoptosis of optic lobe cortical neurons.

115 on detectors found in dragonfly and hoverfly optic lobes demonstrate robust tuning for small objects,

116 ch were retinotopically organized across the optic lobe, demonstrating a hallmark of visual system or

117 Fish retina and tectum, and fly optic lobe, develop from a partitioned, unidirectionally

118 Eye and optic lobe development in the Methoprene-tolerant (Met)-

119 These characteristics allow optic lobe development to be divided into two ecdysteroi

120 e propose that dSno functions as a switch in optic lobe development, shunting Medea from the Dpp path

121 ss of both APCs triggers dramatic defects in optic lobe development.

122 The Drosophila optic lobe develops from neuroepithelial cells, which fu

123 Along the processing chain in the Drosophila optic lobe, directional responses first appear in T4 and

124 B1 (EcR-B1) in the photoreceptors and in the optic lobe, downregulation of proliferation in the optic

125 constructed the complex morphogenesis of the optic lobe during the larval period, and established a r

126 Attention-like effects were reduced in the optic lobes during replay of the same visual sequences,

127 -regulatory region localized a newly derived optic lobe enhancer activity to a region of an intron th

128 We suggest that the novel optic lobe enhancer evolved by exploiting the cryptic ac

129 The Nep1 optic lobe enhancer overlaps with other enhancer activit

130 cyte-like glia, the chiasm giant glia of the optic lobe, epithelial and subperineurial glia on sleep

131 e protocerebrum of Fuxianhuia is supplied by optic lobes evidencing traces of three nested optic cent

132 The optic lobes exhibit the highest levels of polyploidy, as

133 d in the neuropil of the central complex and optic lobe; expression is severely depressed in the muta

134 In the developing Drosophila optic lobe, eyeless, apterous and distal-less, three gen

135 Regulatory genes that are required for eye/optic lobe fate, including sine oculis (so) and eyes abs

136 ring visual system samples (i.e., retina and optic lobe) for confocal microscopy.

137 The optic lobe forms a prominent compartment of the Drosophi

138 Here we present a connectome of the right optic lobe from a male Drosophila melanogaster acquired

139 In Drosophila, neurons in four optic lobe ganglia originate from two neuroepithelia, th

140 ve within-class transcriptomic diversity for optic lobe glia, this could be explained entirely by gli

141 Additional cells in the optic lobe (group 5) and posterior protocerebrum (group

142 Recent connectomic data of the Drosophila optic lobe has suggested a neural circuit for the detect

143 Crz transcripts were also found in the optic lobes; however, these mRNAs do not seem to be tran

144 evelopment of the adult retina and the outer optic lobes in the moth Manduca sexta.

145 sual representation across the layers of the optic lobe, including the emergence of the OFF pathway a

146 ht, and octopamine cells that project to the optic lobes increase in activity during flight.

147 e width; expression analysis guided us to C2 optic-lobe interneurons.

148 iated with motion-sensitive outputs from the optic lobes invades the entire protocerebral bridge and

149 Previous studies have shown that the optic lobe is the motor command center for dynamic body

150 The optic lobe is thought to play a key role in controlling

151 e p196 present in axoplasm and purified from optic lobes is a squid homolog of CBM-V and functions as

152 Hpo/Warts core cascade restrains Yki in the optic lobe, it is dispensable for Yki target gene repres

153 In the developing Drosophila optic lobe, kat80 loss specifically affects the asymmetr

154 agen of the medial brain, the visual system (optic lobe, larval eye) and the stomatogastric nervous s

155 rs (R cells) connect to neurons in different optic lobe layers.

156 However, the optic lobe mass, after controlling for central brain mas

157 d, Sepioteuthis lessoniana Most areas in the optic lobe mediated predominately ipsilateral expansion

158 We use neuroblasts of the Drosophila optic lobe medulla to address these questions and show t

159 input from visual projection neurons of the optic lobe medulla, completing a three-legged circuit th

160 h has evolved a unique expression pattern in optic lobe neuroblasts of Drosophila santomea.

161 nscriptional profile with similarly obtained optic lobe neuroblasts.

162 ling mitotic spindle alignment in Drosophila optic lobe neuroepithelial cells through aPKC activity-d

163 s along a continuous front in the Drosophila optic lobe neuroepithelium to produce neural stem cells

164 ion and cell proliferation in the Drosophila optic lobe neuroepithelium.

165 and in some cases is already present in the optic lobe neurons of T. brassicae.

166 Loss of Acj6 function in larval optic lobe neurons results in disorganized retinal axon

167 oreceptor array, misalignment of retinal and optic lobe neurons, and loss of visual acuity.

168 series of tTFs that specify most Drosophila optic lobe neurons.

169 ed in R cells, accumulates in the developing optic lobe neuropil, and through the analysis of a uniqu

170 ter larval life, develops into the prominent optic lobe neuropiles, and the larval photoreceptor (Bol

171 at direct glia to proper destinations in the optic lobe neuropiles.

172 The shared organization of three optic lobe neuropils-the lamina, medulla, and lobula-lin

173 tions of visual channels, including multiple optic lobe neuropils.

174 d abnormalities in the organization of their optic lobe neuropils.

175 terize genetically identified neurons in the optic lobe of Drosophila that are specifically tuned to

176 ect the function of neuronal subtypes in the optic lobe of Drosophila to reveal their role in motion

177 erstand how color vision is processed in the optic lobe of Drosophila, providing a paradigm for more

178 In the optic lobe of Drosophila, rules of connectivity between

179 intracellular recording and staining in the optic lobe of intact animals.

180 Proliferation of neural precursors in the optic lobe of Manduca sexta is controlled by circulating

181 ant larvae have proliferation defects in the optic lobe of the brain very similar to those seen in ba

182 for proper termination of axons R1-R6 in the optic lobe of the developing Drosophila eye.

183 arkers to characterize a boundary within the optic lobe of the Drosophila brain and found that Slit a

184 The lobula plate in the optic lobe of the fly brain is a high-order processing c

185 elective lobula columnar (LC) neurons in the optic lobe of the fruit fly Drosophila melanogaster to c

186 By electrically stimulating the optic lobe of the oval squids and observing their body p

187 tonin-immunoreactive (5-HTi) neurones in the optic lobe of the praying mantis Tenodera sinensis were

188 rt exceptional preservation of the brain and optic lobes of a stem-group arthropod from 520 million y

189 hematical model for colour processing in the optic lobes of bees to explore how this diversity might

190 ption of the transcriptomic diversity of the optic lobes of Drosophila.

191 Comparing neuronal cell population in the optic lobes of hatchlings and adults, we reveal a switch

192 la complex, the third optic neuropil, in the optic lobes of insects.

193 llular recordings from visual neurons in the optic lobes of Manduca sexta that are selectively activa

194 Weighing brains and optic lobes of seven Myrmecia species, showed that after

195 from two different classes of neurons in the optic lobes of the cuttlefish brain and their synaptic a

196 specific markers for Bolwig's organ and the optic lobe, of tll loss- and gain-of-function mutant emb

197 analysis of a temporal series of tTFs in the optic lobe offers mechanistic insights into how tTF seri

198 e mushroom body (MB), and innervation of the optic lobe (OL) medulla by R7 photoreceptors.

199 B calyces and peduncle, antennal lobes (AL), optic lobes (OL), central complex (CX), and whole brains

200 he Drosophila visual processing centre - the optic lobes (OLs), medulla NBs derived from the neuroepi

201 se that all lineages of the central brain or optic lobe, or both, show expression; and 2) expression

202 s were differentially expressed in the eyes, optic lobes, or central brain of white and yellow H. cyd

203 Neural stem cells in the Drosophila optic lobe originate within a polarised neuroepithelium,

204 d to other tissues like gills, skin, mantle, optic lobe, ovaries, and brain.

205 discovered synapse-level connectomes in the optic lobe, particularly in ON-pathway (T4) receptive-fi

206 the OOA, which in turn has severe effects on optic lobe patterning.

207 e of the four, primary neuropiles of the fly optic lobe--performs this visual discrimination.

208 ression initiates neurogenesis in the larval optic lobe primordium and drives the sequential transiti

209 Disco autoregulates its transcription in the optic lobe primordium by direct binding to a regulatory

210 We find that disco expression in the optic lobe primordium, a group of cells contacted by the

211 xpression of tll is normally confined to the optic lobe primordium, whereas ato appears in a subset o

212 The embryonic visual system consists of the optic lobe primordium, which, during later larval life,

213 he endogenous disco gene specifically in the optic lobe primordium.

214 infer that signaling from the retina to the optic lobe prompts a feedback signal to retinal PRs.

215 Photoreceptors project to the optic lobes: R1-R6, which are involved in motion detecti

216 to understand how the cephalopod retina and optic lobes relate to the vertebrate retina.

217 edulla supplying deep neuropils of the fly's optic lobes reveal different filter properties among the

218 inputs from multiple sources, including the optic lobe's lobula.

219 ntral nerve cord (VNC) (motor) and the adult optic lobes (sensory).

220 Throughout this period, the optic lobes show NADPH-diaphorase activity and stain wit

221 they all have large eyes, relatively larger optic lobes, smaller mushroom bodies, and similarly size

222 g either classical calpain or atypical small optic lobe (SOL) calpain 2 d after 5-HT treatment or pai

223 s non-associative LTF is blocked by dn small optic lobe (SOL) calpain.

224 rotease belonging to the non-classical small optic lobe (SOL) family of calpains, an important class

225 mide, stained cells and fibers in the brain, optic lobes, subesophageal ganglion, and thoracico-abdom

226 In the fruit fly optic lobe, T4 and T5 cells represent the first directio

227 soluble guanylate cyclase (sGC), whereas the optic lobe targets express NO synthase.

228 ve cloned a Kv2 potassium channel from squid optic lobe termed sqKv2.

229 aller brains for their body mass and smaller optic lobes than volant pan-alcids.

230 While males have larger optic lobes than workers, their collar region is smaller

231 hat a single cell expressed corazonin in the optic lobes that belonged to the group of medial AME int

232 characterize those neurons in the Drosophila optic lobes that possibly release gamma aminobutyric aci

233 In the Drosophila larval optic lobe, the generation of neural stem cells involves

234 notopy by inducing their target field in the optic lobe, the lamina neurons, with a secreted differen

235 ject their axons to one of two layers in the optic lobe, the lamina or the medulla.

236 lifera, the neurons' dendritic fields in the optic lobes, the medulla and lobula, and the organizatio

237 In the Drosophila optic lobes, the medulla processes visual information co

238 n has its most important consequences in the optic lobes, the thoracic ganglia, or both, depending in

239 the lamina, the first neuropil of the adult optic lobe: those that arise from precursors in the eye-

240 ormed into dorsolateral structures, i.e. eye/optic lobe tissue, which causes a continuous visual prim

241 We applied electrical stimulation within the optic lobe to investigate the neural basis of body patte

242 s synapse onto neurons that project from the optic lobe to the central brain(12,13), which are conjec

243 columnar (LC) neuron types project from the optic lobe to the central brain, where each forms a glom

244 (10,14,15), which connect the medulla in the optic lobe to the small unit of the anterior optic tuber

245 basic visual pathway to the memory centres (Optic Lobes to Mushroom Bodies) involved in the storage

246 former comprising centripetal cells from the optic lobes to the midbrain, the latter comprising centr

247 ing center of the octopus central brain, the optic lobe, to determine how basic features of the visua

248 l protocerebrum and the other that exits the optic lobes toward the supraesophageal ganglion.

249 FMRF-amide-based retrograde signal from the optic lobe towards the retina that supports the function

250 eparin sulfate proteoglycan Terribly Reduced Optic Lobes (Trol) is the Drosophila melanogaster homolo

251 ) which was subsequently purified from squid optic lobes using a modification of a protocol for the p

252 c inputs of several hundred Tm9s across both optic lobes using the full adult female fly brain (FAFB)

253 tely 220 kDa protein was purified from squid optic lobe, using a biochemical protocol designed to iso

254 ereas, as expected, the relative size of the optic lobes varies strongly across species.

255 s visual information from the medulla of the optic lobe via the anterior optic tubercle (AOTU) and bu

256 dendritic fields of the MeTu neurons in the optic lobes, we infer potential visual features and the

257 pressed after photoreceptor outgrowth to the optic lobe, when retinal growth cones are actively selec

258 ressed and required in target neurons in the optic lobe, whereas Jeb is primarily generated by photor

259 e single-cell molecular atlas of the octopus optic lobe, which is the primary visual processing struc

260 ating sequences of individual columns in the optic lobe with a telescope while recording from single

261 t the discovery of neurons in the Drosophila optic lobe with hue-selective properties, which enables

262 s share only the ventrolateralization of the optic lobe with their closest non-volant relatives, the

263 the anterior visual pathway, connecting the optic lobes with the central complex via the anterior op

264 -L5), making it the simplest neuropil in the optic lobe, yet how this diversity is generated was unkn