ライフサイエンスコーパス: optic neuropathy

1 al vasculitis, 3 papilledema, 2 infiltrative optic neuropathy).

2 wing a variable eye phenotype (i.e. uveitis, optic neuropathy).

3 , and 3 patients developed an EVD-associated optic neuropathy.

4 agnostic testing in patients with this acute optic neuropathy.

5 ransaminase elevation, and 1 (4.8%) ischemic optic neuropathy.

6 diagnosis and follow-up of patients with an optic neuropathy.

7 perfusion, which suggests early glaucomatous optic neuropathy.

8 ion between amiodarone and the occurrence of optic neuropathy.

9 exposure in the development of glaucomatous optic neuropathy.

10 assess color identification in patients with optic neuropathy.

11 sive investigation ruled out other causes of optic neuropathy.

12 ogression and the development of compressive optic neuropathy.

13 the most common cause of Leber's hereditary optic neuropathy.

14 CAT p.L81R and p.R212W mutations can lead to optic neuropathy.

15 e measure was the development of compressive optic neuropathy.

16 ts, including those affected by glaucomatous optic neuropathy.

17 gns of chronic angle damage and glaucomatous optic neuropathy.

18 er retina with age and in a model of chronic optic neuropathy.

19 ransection (pONT) is an established model of optic neuropathy.

20 tic role of 5-fluoruracil in 5-FU associated optic neuropathy.

21 tivation and cell death in a rodent model of optic neuropathy.

22 ermitted visualization of the characteristic optic neuropathy.

23 in eye movements, accommodation problems, or optic neuropathy.

24 tic nerve oedema and a subsequent left sided optic neuropathy.

25 e predictive of visual recovery in traumatic optic neuropathy.

26 can lead to the development of glaucomatous optic neuropathy.

27 tion of neurodegeneration that occurs during optic neuropathy.

28 ompressive optic neuropathy in patients with optic neuropathy.

29 e development or progression of glaucomatous optic neuropathy.

30 medial wall contour were not associated with optic neuropathy.

31 tal recti diameter (P = 0.016) predictive of optic neuropathy.

32 development and progression of glaucomatous optic neuropathy.

33 that cause pain, disfigurement, diplopia, or optic neuropathy.

34 to be a significant independent predictor of optic neuropathy.

35 nd in patients with papilledema and ischemic optic neuropathy.

36 from either typical clinical or sub-clinical optic neuropathy.

37 gic manifestations, as in Leber's hereditary optic neuropathy.

38 set retinal dysfunction with similarities to optic neuropathy.

39 he likelihood of neurologic and glaucomatous optic neuropathy.

40 ts (18%) showed retinitis or uveitis without optic neuropathy.

41 optic neuropathies such as Leber Hereditary Optic Neuropathy.

42 fiber layer, that resembles the phenotype of optic neuropathy.

43 loss of visual acuity in Leber's hereditary optic neuropathy.

44 l ganglion cell (RGC) death, the endpoint of optic neuropathy.

45 hronic development of bilateral glaucomatous optic neuropathy.

46 considered for the novel indication of human optic neuropathy.

47 omitant epiretinal membrane and glaucomatous optic neuropathy.

48 ctive of bioenergetic loss in cell models of optic neuropathy.

49 diation-induced retinopathy, maculopathy, or optic neuropathy.

50 nal membranes, with and without glaucomatous optic neuropathy.

51 neurodegeneration in glaucoma and prevalent optic neuropathies.

52 henotyping of the heterogeneous inflammatory optic neuropathies.

53 ptic neuritis, and compressive and inherited optic neuropathies.

54 al share of families with unsolved inherited optic neuropathies.

55 tients with glaucomatous and nonglaucomatous optic neuropathies.

56 t than in other quadrants in nonglaucomatous optic neuropathies.

57 skills in the evaluation of nonglaucomatous optic neuropathies.

58 NFL in both glaucomatous and nonglaucomatous optic neuropathies.

59 ns of RNFL loss in different nonglaucomatous optic neuropathies.

60 that affect mitochondrial function result in optic neuropathies.

61 e a ready source of replacement RGCs in such optic neuropathies.

62 r studying the pathobiology of mitochondrial optic neuropathies.

63 children, to serve in evaluating those with optic neuropathies.

64 ischemic optic neuropathy (25%), compressive optic neuropathy (18.7%) and hereditary optic neuropathy

65 sive optic neuropathy (18.7%) and hereditary optic neuropathy (18.7%).

66 radiation maculopathy (43.1%) and radiation optic neuropathy (20.8%) developing at a mean of 27 mont

67 The most common diagnoses were ischemic optic neuropathy (25%), compressive optic neuropathy (18

68 thy (66% of patients), followed by radiation optic neuropathy (51% of patients).

69 ities (eg, amblyopia, nystagmus, foveopathy, optic neuropathy) accounted for residual postoperative s

70 Acute optic neuritis is the most common optic neuropathy affecting young adults.

71 Optic neuropathy after PPV for macula-sparing primary RR

72 Twenty-two subjects with optic neuropathy (aged 18-65) and 18 control subjects we

73 l changes following murine anterior ischemic optic neuropathy (AION) by using spectral-domain optical

74 report a case of bilateral anterior ischemic optic neuropathy (AION) showing histopathologic evidence

75 pared: 30 normals, 20 with anterior ischemic optic neuropathy (AION), and 25 with papilledema and int

76 Eyes with MME were compared with eyes with optic neuropathy alone and to healthy fellow eyes.

77 lowing future studies on disease modeling of optic neuropathies and development of cell therapies.

78 al purposes to assess disease progression in optic neuropathies and diseases that affect the central

79 nstem features mainly, two had demyelinating optic neuropathies and one had an unclear diagnosis.

80 th that are common in the existing models of optic neuropathies and optic nerve lesions.

81 regarding the use of OCT in nonglaucomatous optic neuropathies and sheds light on common patterns of

82 were misdiagnosed as glaucoma (two ischemic optic neuropathies and two congenital optic disc anomali

83 dred eyes from 74 patients with glaucomatous optic neuropathy and a 24-2 VF with mean deviation bette

84 All 12 patients with optic neuropathy and a documented fundus examination at

85 Glaucoma is a progressive optic neuropathy and a leading cause of blindness.

86 m responsible for RGC early degeneration and optic neuropathy and linking RTN4IP1 functions to mitoch

87 onal deficiency definitively proved to cause optic neuropathy and loss of vision.

88 The study of optic neuropathy and neurologic manifestations of demyel

89 24 months after the occurrence of radiation optic neuropathy and optic disc imaging during follow-up

90 The pattern of RNFL thinning in ischemic optic neuropathy and optic nerve head drusen is more lik

91 tified risk factors associated with ischemic optic neuropathy and prone spinal fusion surgery.

92 function and death, as in Leber's hereditary Optic Neuropathy and suggests novel therapeutic routes t

93 ; median interval between onset of radiation optic neuropathy and the last patient visit was 34 month

94 gical conditions that may mimic glaucomatous optic neuropathy and to determine which most often lead

95 (RGC) populations in histological samples of optic neuropathies, and early work in this field suggest

96 t additionally lead to ocular motor palsies, optic neuropathies, and orbital pathologies.

97 ients, 48 were observed only after radiation optic neuropathy, and 45 were treated with intravitreal

98 , death, enucleation, radiation retinopathy, optic neuropathy, and best-corrected visual acuity (BCVA

99 d as POAG (open drainage angle, glaucomatous optic neuropathy, and glaucomatous field defect), glauco

100 atment of glaucoma, nonglaucomatous forms of optic neuropathy, and perhaps other CNS neurodegeneratio

101 attributed to radiation-induced retinopathy, optic neuropathy, and secondary glaucoma.

102 ermined age, sex, visual acuity, etiology of optic neuropathy, and the temporal and spatial character

103 n of 14 months (3-86 months) after radiation optic neuropathy; and of 45 intravitreally treated patie

104 Optic neuropathies are a group of optic nerve (ON) disea

105 Optic neuropathies are associated with death of retinal

106 Optic neuropathies are characterised by a loss of retina

107 The mechanisms underlying optic neuropathies are diverse and typically manifest wi

108 Autosomal-recessive optic neuropathies are rare blinding conditions related

109 Inherited optic neuropathies are rare eye diseases of optic nerve

110 Disorders of the optic nerves (optic neuropathies) are some of the most common causes o

111 se, including glaucomatous and mitochondrial optic neuropathies, are linked increasingly to dysfuncti

112 l optic neuropathies-especially inflammatory optic neuropathies-are associated with neurological diso

113 or optic neuritis and MS, and possibly other optic neuropathies as well.

114 scans, was equally predictive of compressive optic neuropathy as the more involved volumetric calcula

115 mechanisms resulting in the loss of RGCs in optic neuropathies, as well as the development of target

116 ntral nervous system (CNS) demyelination and optic neuropathy, as determined by changes in visual evo

117 Glaucoma is a group of optic neuropathies associated with aging and sensitivity

118 aimed at modifying risk factors for ischemic optic neuropathy associated with prone spinal fusion sur

119 Eyes affected by glaucomatous optic neuropathy at presentation were excluded.

120 Patients with compressive optic neuropathy at the time of presentation were exclud

121 se model of blast-induced indirect traumatic optic neuropathy (bITON) showed that PPS and PLGA MP-med

122 t the use of idebenone in Leber's hereditary optic neuropathy, but this has not been evaluated in a r

123 nerve head perfusion and cause glaucomatous optic neuropathy by creating transient hypoxemia and inc

124 ewed the charts of consecutive patients with optic neuropathies caused by neurophthalmological condit

125 oma comprises a distinctive group of chronic optic neuropathies, characterised by the progressive los

126 The glaucomas are a group of progressive optic neuropathies characterized by degeneration of reti

127 Glaucoma is a progressive optic neuropathy characterized by loss of retinal gangli

128 Glaucoma is a multifactorial optic neuropathy characterized by retinal ganglion cell

129 Glaucoma is an optic neuropathy characterized by retinal ganglion cells

130 Glaucoma is an optic neuropathy, commonly associated with elevated intr

131 wo novel principles of genetic mechanisms in optic neuropathies: deep intronic OPA1 mutations, which

132 ed on clinical examination with glaucomatous optic neuropathy defined by the presence of neuroretinal

133 atient also developed bilateral glaucomatous optic neuropathy despite a well-controlled intraocular p

134 During the observational period, optic neuropathy developed in 17 amiodarone-treated pati

135 Anterior ischemic optic neuropathy developed in one patient in the group t

136 darone use remained a significant factor for optic neuropathy development among male subjects (HR, 3.

137 iated with a nearly 3-fold increased risk of optic neuropathy development compared with female gender

138 y (mean clinical activity score, 6.2) but no optic neuropathy, diabetes, recent steroid treatment, pr

139 a wide range of other neurodegenerative and optic neuropathy diseases.

140 enlargement in the development of dysthyroid optic neuropathy (DON) in Graves' orbitopathy (GO).

141 Dysthyroid optic neuropathy (DON) is the commonest cause of blindne

142 of the optic disc had the largest impact on optic neuropathy, dose to 20% of cornea had the largest

143 trial in 85 patients with Leber's hereditary optic neuropathy due to m.3460G>A, m.11778G>A, and m.144

144 Several optic neuropathies-especially inflammatory optic neuropa

145 es such as beriberi, neurological disorders, optic neuropathy, etc.

146 ies who self-registered for the Glaucomatous Optic Neuropathy Evaluation (GONE) Project from December

147 ed as responsible for an autosomal recessive optic neuropathy from a Chinese consanguineous family.

148 olfactomedin (OLF) domain are linked to the optic neuropathy glaucoma.

149 re, the critical stressor in the most common optic neuropathy, glaucoma.

150 re, the critical stressor in the most common optic neuropathy, glaucoma.

151 on the basis of the presence of glaucomatous optic neuropathy (GON) and 24-2 visual field abnormaliti

152 ents (57.4 +/- 13.2 years) with glaucomatous optic neuropathy (GON) and 45 eyes of 45 controls (48.0

153 In patients with glaucomatous optic neuropathy (GON) and pathologic optic nerve DIR hy

154 hs of subjects with and without glaucomatous optic neuropathy (GON) followed during the first 13 year

155 dy (ADAGES) with a diagnosis of glaucomatous optic neuropathy (GON) or ocular hypertension (OHT) and

156 the feasibility of identifying glaucomatous optic neuropathy (GON) using IOP corrected and uncorrect

157 rative diabetic retinopathy and glaucomatous optic neuropathies (GONs).

158 t optic atrophy + group compared to the pure optic neuropathy group, implicating a causal role for th

159 isual field abnormality but not glaucomatous optic neuropathy had a higher tendency to be missed by d

160 average of 3.2 years follow-up, compressive optic neuropathy had developed in 17% (25/144) of Group

161 At last follow-up, all 7 patients with optic neuropathy had visual acuity less than 20/200, rel

162 gher daily dose did not increase the risk of optic neuropathy (HR, 0.96; 95% CI, 0.91-1.00; P = 0.07)

163 ated patients had a 2-fold increased risk of optic neuropathy (HR, 2.09; 95% CI, 1.13-3.85; P = 0.02)

164 ith prone spinal fusion surgery and ischemic optic neuropathy identified in a large multicenter case-

165 OCT has the potential to monitor progressive optic neuropathies in young children who have difficulty

166 Retinopathy was seen in 31 patients (37.8%), optic neuropathy in 12 (14.6%), and cataracts in 26 (31.

167 taract in 19, glaucoma in 9, nonglaucomatous optic neuropathy in 3, corneal opacities in 3, retinal d

168 We demonstrated an age-related optic neuropathy in AD by OCT, with a significant reduct

169 f ocular complications including uveitis and optic neuropathy in EVD survivors, level of VA impairmen

170 These results demonstrated a higher risk of optic neuropathy in patients treated with amiodarone, es

171 ortant quantifiable predictor of compressive optic neuropathy in patients with optic neuropathy.

172 red as a possible contributing factor in the optic neuropathy in the DBA/2J mouse model of glaucoma.

173 f bilateral optic disc oedema and associated optic neuropathy in the setting of FOLFOX chemotherapy.

174 The treatment of mitochondrial optic neuropathy in the US is only supportive.

175 blindness worldwide, is a neurodegenerative optic neuropathy in which vision loss is caused by loss

176 Inherited optic neuropathies include complex phenotypes, mostly dr

177 umetric univariate predictors of compressive optic neuropathy included medial rectus volume (P = 0.00

178 ar geometry are associated with glaucomatous optic neuropathy independently of vascular risk factors

179 edian of 12.5 months (1-55 months) following optic neuropathy, indicating no statistically significan

180 Expression of human ND4 and rescue of optic neuropathy induced by mutant human ND4.

181 The cause of ischemic optic neuropathy (ION) as the most complex entity of POV

182 have demonstrated the occurrence of ischemic optic neuropathy (ION) following intravitreal injections

183 It is a sign of optic neuropathy irrespective of its etiology.

184 Optic neuropathy is a major cause of irreversible blindn

185 Radiation-induced optic neuropathy is an expected issue after proton beam

186 Compressive optic neuropathy is associated with significantly thinne

187 Traumatic optic neuropathy is common clinical problem for neuro-op

188 optic disc oedema and associated left sided optic neuropathy is described.

189 complex neurological phenotypes that involve optic neuropathy is puzzling.

190 Leber's hereditary optic neuropathy is the most common mitochondrial DNA di

191 of blindness worldwide and, along with other optic neuropathies, is characterized by loss of retinal

192 open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable disease.

193 gene responsible for 70% of Leber Hereditary Optic Neuropathies (LHON).

194 Leber's hereditary optic neuropathy (LHON) and a multiple sclerosis (MS)-li

195 tic neuropathies, such as Leber's hereditary optic neuropathy (LHON) and Autosomal dominant optic atr

196 have been associated with Leber's hereditary optic neuropathy (LHON) and their pathophysiology remain

197 l strategy for treatment of Leber hereditary optic neuropathy (LHON) caused by a mutation in the nico

198 ndrial gene responsible for Leber hereditary optic neuropathy (LHON) into the mouse germ line using f

199 Leber's hereditary optic neuropathy (LHON) is a classical mitochondrial dis

200 Leber hereditary optic neuropathy (LHON) is a degenerative disease of the

201 Leber hereditary optic neuropathy (LHON) is a disorder characterized by s

202 Leber's hereditary optic neuropathy (LHON) is a maternally inherited blindi

203 Leber's hereditary optic neuropathy (LHON) is a mitochondrial disease affec

204 Leber's hereditary optic neuropathy (LHON) is a rare genetic mitochondrial

205 Leber hereditary optic neuropathy (LHON) is a syndrome of subacute loss o

206 natural history of G11778A Leber hereditary optic neuropathy (LHON) is important to determine the op

207 Leber's hereditary optic neuropathy (LHON) is the most common mitochondrial

208 Leber's hereditary optic neuropathy (LHON) is the most common mitochondrial

209 Leber's hereditary optic neuropathy (LHON) is typically characterized by va

210 An animal model of Leber hereditary optic neuropathy (LHON) was produced by introducing the

211 Leber's hereditary optic neuropathy (LHON), a mitochondrial disease, has cl

212 eat the Complex I disease Leber's hereditary optic neuropathy (LHON), but has been less successful in

213 te the natural history of Leber's hereditary optic neuropathy (LHON).

214 syndrome (NARP-MILS), and Leber's hereditary optic neuropathy (LHON).

215 F)-P1ND4v2 in patients with Leber hereditary optic neuropathy (LHON).

216 Common mutations for Leber's hereditary optic neuropathy (LHON: G11778A; T14484C; and G3460A) we

217 NA levels responsible for Leber's hereditary optic neuropathy (LHOND), and neurogenic muscle weakness

218 n (2%), partial choroidal ischemia (2%), and optic neuropathy (<1%).

219 Optic neuropathies may range from non-syndromic genetic

220 cell death in rodent glaucoma and traumatic optic neuropathy models.

221 ; n = 3), and nonarteritic anterior ischemic optic neuropathy (n = 1) in the repositioning group, and

222 drome (OIS), non-arteritic anterior ischemic optic neuropathy (NA-AION) and amaurosis fugax (AF).

223 management of nonarteritic anterior ischemic optic neuropathy (NA-AION) and central retinal artery oc

224 patients with nonarteritic anterior ischemic optic neuropathy (NA-AION).

225 euritis (14), nonarteritic anterior ischemic optic neuropathy (NAION) (21), and ONH swelling (average

226 f concurrent non-arteritic anterior ischemic optic neuropathy (NAION) and cilioretinal arteries occlu

227 patients with nonarteritic anterior ischemic optic neuropathy (NAION) and its influence on second eye

228 ts with acute nonarteritic anterior ischemic optic neuropathy (NAION) and normal age-related cataract

229 ncreases the risk of non-arteritic ischaemic optic neuropathy (NAION) and the second eye involvement.

230 Nonarteritic anterior ischemic optic neuropathy (NAION) is a devastating ocular conditi

231 physiology of nonarteritic anterior ischemic optic neuropathy (NAION) is not completely understood.

232 To date, non arteritic anterior ischemic optic neuropathy (NAION) is still incurable.

233 diagnosis of nonarteritic anterior ischemic optic neuropathy (NAION) seen in the Wilmer Eye Network

234 eater risk of nonarteritic anterior ischemic optic neuropathy (NAION) than nondiabetic patients.

235 r unilateral non-arteritic anterior ischemic optic neuropathy (NAION) will eventually develop the sam

236 neuritis and nonarteritic anterior ischemic optic neuropathy (NAION), conditions without intracrania

237 phy (OCT), in nonarteritic anterior ischemic optic neuropathy (NAION).

238 ge following non-arteritic anterior ischemic optic neuropathy (NAION).

239 ith chronic non-arteritic anterior ischaemic optic neuropathy (NAION).

240 tension glaucoma (NTG) and non-glaucomatous optic neuropathies (NGON).

241 VEPs can be valuable in diagnosing optic neuropathies, nonorganic visual loss, and assessin

242 halmologic diagnosis (amblyopia, strabismus, optic neuropathy, nystagmus, or retinopathy of prematuri

243 1; 95% CI, 1.34-100.56; P = .03) or ischemic optic neuropathy (odds ratio, 5.27; 95% CI, 1.61-17.23;

244 The genetic diagnosis in inherited optic neuropathies often remains challenging, and the em

245 ultiple sclerosis with chronic demyelinating optic neuropathy on stable immunomodulatory therapy.

246 al signs of radiation retinopathy, radiation optic neuropathy, or both.

247 re was no evidence of radiation retinopathy, optic neuropathy, or cataract.

248 edema (CME), macular scarring, macular hole, optic neuropathy, or macular ischemia.

249 lly other reasons, such as radiation-induced optic neuropathy, or where visual outcome was influenced

250 ion of >/= 10 mmHg and incident glaucomatous optic neuropathy over the first 2 years compared with th

251 n the Ndufs4 KO mouse model of mitochondrial optic neuropathy, papaverine and zolpidem provided signi

252 lence and incidence of post-cataract surgery optic neuropathy (PCSON) in the modern era.

253 graphic evidence of progressive glaucomatous optic neuropathy (PGON).

254 Docetaxel can cause a toxic optic neuropathy possibly due to an ischemic or neurotox

255 tients with neuro-ophthalmic manifestations, optic neuropathy presented with optic disc edema, often

256 ith NTG and 54 with NGON, including ischemic optic neuropathy, previous optic neuritis, and compressi

257 peripheral nervous system, include deafness, optic neuropathy-previously not reported in HSAN IE-larg

258 e mitochondrial disorder, Leber's hereditary optic neuropathy, provides evidence that patients with d

259 ects including postoperative vision changes, optic neuropathy, radiation retinopathy, and cataract.

260 Rodent anterior ischemic optic neuropathy (rAION) is an optic nerve infarct, whic

261 -year freedom from radiation retinopathy and optic neuropathy rates were higher in the apex LD than H

262 examined 118 patients with anterior ischemic optic neuropathy referred to a tertiary care center from

263 t common side effects were radiation-induced optic neuropathy, retinopathy, and cataract.

264 of >360 subjects with unexplained inherited optic neuropathy revealed three additional families carr

265 travitreal bevacizumab to suppress radiation optic neuropathy (RON) or maculopathy.

266 To describe the first reported case of toxic optic neuropathy secondary to docetaxel (Taxotere(R)) ch

267 multisystemic, some are tissue specific--eg, optic neuropathy, sensorineural deafness, and type 2 dia

268 ated with intravitreal therapy for radiation optic neuropathy showed no statistically significant dif

269 OCT-measured RNFL in nonglaucomatous optic neuropathies shows thinning, which may mimic those

270 ement-based therapies for glaucoma and other optic neuropathies.SIGNIFICANCE STATEMENT Glaucoma is th

271 GCs and provide effective neuroprotection in optic neuropathies.SIGNIFICANCE STATEMENT Here, we prese

272 diseases such as glaucoma, or in compressive optic neuropathies such as from optic glioma.

273 th could lead to novel therapies for chronic optic neuropathies such as glaucoma.

274 pies for currently untreatable mitochondrial optic neuropathies such as Leber Hereditary Optic Neurop

275 des might in susceptible individuals lead to optic neuropathies such as normal tension glaucoma.

276 Inherited mitochondrial optic neuropathies, such as Leber's hereditary optic neu

277 le (19% vs. 18% at 5 years), whereas that of optic neuropathy tended to be higher with the 15-mm plaq

278 exhibited significantly higher penetrance of optic neuropathy than those carrying only m.11778G > A m

279 Glaucoma is a group of progressive optic neuropathies that share common biological and clin

280 ens up a promising gene therapy strategy for optic neuropathies, the most common form of eye diseases

281 I have also led to advances in understanding optic neuropathies, the ocular motor system, pseudotumor

282 Given that vitamin B12 deficiency causes an optic neuropathy through unknown mechanisms and that it

283 e change in visual acuity from occurrence of optic neuropathy to final visual acuity, no statisticall

284 rsy about the primary treatment of traumatic optic neuropathy (TON) has anchored on final vision foll

285 Traumatic optic neuropathy (TON) is a devastating cause of permane

286 Traumatic optic neuropathy (TON) is an acute injury of the optic n

287 dary to orbital and facial trauma: traumatic optic neuropathy (TON), retrobulbar haemorrhage (RBH) an

288 The rate of compressive optic neuropathy was significantly lower and improvement

289 In four families with early-onset recessive optic neuropathy, we identified mutations in RTN4IP1, wh

290 ion, amblyopia, advanced glaucoma, and other optic neuropathies were excluded from the analysis of vi

291 In our study, isquemic and compressive optic neuropathies were the ones that most often did so.

292 Patients with OHT or glaucomatous optic neuropathy were recruited, and photopic full-field

293 with unilateral or asymmetric demyelinating optic neuropathy were retrospectively evaluated.

294 O and parkinsonism/dementia with subclinical optic neuropathy widens the phenotypic spectrum of OPA1

295 ent ICH, is associated with greatest risk of optic neuropathy with CS.

296 a trend of increased cumulative incidence of optic neuropathy with longer treatment duration (>41 vs.

297 Early POAG subjects had glaucomatous optic neuropathy with mild, reproducible visual field lo

298 (SSBP1) in patients with apparently dominant optic neuropathy with or without extraocular phenotypes.

299 idocorneal angles and displayed glaucomatous optic neuropathy with visual field defects.

300 Fourteen of 17 patients (82%) demonstrated optic neuropathy, with 12 of these patients also showing