ライフサイエンスコーパス: optical tweezer

1 h mediation by dynamic holographic assembly (optical tweezers).

2 d beads suspended in water and acetone by an optical tweezer.

3 orce microscope probe coupled to a plasmonic optical tweezer.

4 th other single-molecule techniques, such as optical tweezers.

5 forces, which have been mostly restricted to optical tweezers.

6 errors in measurements of folding made using optical tweezers.

7 quantum and classical information science or optical tweezers.

8 rimental data of single protein folding from optical tweezers.

9 cal force at the single-molecule level using optical tweezers.

10 imeric chaperone Hsp90 using single-molecule optical tweezers.

11 quent initiation processes in real time with optical tweezers.

12 characterize its mechanical properties with optical tweezers.

13 le DNA molecules in bacteriophage phi29 with optical tweezers.

14 tructure, which is monitored in real time by optical tweezers.

15 two laser-cooled (87)Rb atoms trapped in two optical tweezers.

16 and single-molecule force spectroscopy with optical tweezers.

17 single-molecule level using high-resolution optical tweezers.

18 y developed to apply and measure force using optical tweezers.

19 ere measured at the single-molecule level by optical tweezers.

20 re in line with previous studies that employ optical tweezers.

21 ith high precision under varying loads using optical tweezers.

22 e on the electrode is thus controlled by the optical tweezers.

23 some-bound stalled nascent polypeptides with optical tweezers.

24 ttering, measuring zeta potential, and using optical tweezers.

25 n, and confirm that this effect occurs using optical tweezers.

26 ng a combination of single molecule FRET and optical tweezers.

27 G-quadruplexes bound to telomestatin, using optical tweezers.

28 ces using polystyrene beads manipulated with optical tweezers.

29 as is it being synthesized in real-time, via optical tweezers.

30 d nucleotide conditions using high-precision optical tweezers.

31 , angular-optical, micropipette, and magneto-optical tweezers.

32 ys of individual strontium atoms held within optical tweezers.

33 g was overcome by trapping particles with 2D optical tweezers.

34 e-by-stage complexity by simply removing the optical tweezers.

35 oscopy and while trapping individual GUVs in optical tweezers.

36 cles on a colloidal monolayer substrate with optical tweezers.

37 of Kif15 at the single-molecule level using optical tweezers.

38 irpins held under tension in high-resolution optical tweezers.

39 killing LRP-overlying cells by ablation with optical tweezers.

40 Similar to optical tweezers, acoustic tweezers have been proposed t

41 Here, we present the all-fiber modular optical tweezers (AFMOTs), in which an optical trap can

42 a range of constant stretching forces using optical tweezers, allowing direct characterization of th

43 ing both ends through attached beads held by optical tweezers, allowing us to record the applied forc

44 The use of optical tweezers also enables the directed deposition an

45 cal counterparts (10,000,000 times less than optical tweezers and 100 times less than optoelectronic

46 e 'motor' on bare DNA, using high-resolution optical tweezers and a 'tethered' translocase system.

47 s and inhomogeneous levan-DNA mixtures using optical tweezers and a rotational rheometer.

48 ave developed a noninvasive flow probe using optical tweezers and a viscous flow model in order to de

49 wnian dynamics experiments using holographic optical tweezers and achieve a doubling of escape rates

50 le-molecule manipulation techniques, notably optical tweezers and AFM.

51 Optical tweezers and atomic force microscopy-based singl

52 ation of circular dichroism, thermodynamics, optical tweezers and calorimetry techniques.

53 nding, double-stranded DNA is stretched with optical tweezers and exposed to ligand under constant ap

54 eloped a single-molecule technique combining optical tweezers and fluorescence microscopy that allows

55 rameters of fibrin and used a combination of optical tweezers and fluorescence microscopy to measure

56 FP technology in plant endomembranes, namely optical tweezers and forward genetics approaches, which

57 ere, we use a combination of single-molecule optical tweezers and MD simulations to investigate the e

58 Here we use optical tweezers and molecular dynamics to dissect chang

59 esis by individual ribosomes using dual-trap optical tweezers and observe simultaneous folding of the

60 include the manipulation of living cells by optical tweezers and optical cooling in atomic physics.

61 Using single molecule optical tweezers and R1597W, we measured the force depen

62 An integrated holographic optical tweezers and Raman microscope was used to invest

63 protein (ACBP) in the low-force regime using optical tweezers and ratcheted molecular dynamics simula

64 FP into different conformational states with optical tweezers and simultaneously probing the chromoph

65 Using optical tweezers and the conventional single-bead assay,

66 ers that combine the nanometer resolution of optical tweezers and the easy manipulation of magnetic t

67 ting on single molecules of duplex DNA using optical tweezers and video fluorescence microscopy.

68 FM) or a scanning electron microscope (SEM), optical tweezers, and focused electron-beam nanomanipula

69 we use single-molecule unfolding studies by optical tweezers, and frameshifting assays to elucidate

70 Here, we combine fluorescence microscopy, optical tweezers, and microfluidics to visualize the ass

71 th different sequences held under tension in optical tweezers, and path shapes were computed by avera

72 cted is positioned in one microchannel using optical tweezers, and the transfection agent is located

73 ts-the most common biological application of optical tweezers-and may guide the development of more r

74 measurements of microdroplets using aerosol optical tweezers (AOT) and analysis of the whispering ga

75 l (SOA) on a droplet suspended in an aerosol optical tweezers (AOT).

76 Using an optical tweezers apparatus, we demonstrate three-dimensi

77 Here we use a single-molecule optical tweezers approach to induce the selective unfold

78 Optical tweezers are a highly versatile tool for explora

79 Optical tweezers are a laboratory-based platform that ca

80 Plasmonic optical tweezers are a ubiquitous tool for the precise m

81 imental single-molecule curves obtained with optical tweezers are also presented, and they show remar

82 Miniaturization and integration of optical tweezers are attractive.

83 r work demonstrates that dynamic holographic optical tweezers are capable of manipulating single micr

84 Dual-trap optical tweezers are often used in high-resolution measu

85 n of single motor proteins, such as FRET and optical tweezers, are limited to a resolution of approxi

86 ed on atomic force microscopy or magnetic or optical tweezers, are powerful but limited in their appl

87 molecule manipulation methods, in particular optical tweezers, are shedding new light on the molecula

88 In this work, we report on creating an optical tweezer array of laser-cooled calcium monofluori

89 Here we implement a configurable optical tweezer array over a planar photonic circuit tai

90 0(-16) (tau/s)(-1/2) These results establish optical tweezer arrays as a powerful tool for coherent c

91 cooling of chiral molecules and, eventually, optical tweezer arrays of complex polyatomic species.

92 Optical tweezer arrays of laser-cooled molecules, which

93 Our work establishes laser-cooled atoms in optical tweezers as a promising route to bottom-up engin

94 ploratory study to assess the use of aerosol optical tweezers as an instrument for sampling and detec

95 Here, we developed a single-molecule optical tweezers assay capable of simultaneously charact

96 Here, using a single-molecule optical tweezers assay on mRNA hairpins, we find that th

97 Here, we present a novel optical tweezers assay that allows monitoring the activi

98 We have developed an optical tweezers assay to follow individual Pol II compl

99 Here, we use a dual-beam optical tweezers assay to study the mechanics of this in

100 Using a single-molecule optical tweezers assay, we explore the effects of oligom

101 Using an optical-tweezers assay, we measured the binding kinetics

102 ied primarily on atomic force microscope and optical tweezers assays that, while powerful, are limite

103 Although optical tweezers based on far-fields have proven highly

104 We present a holographic optical tweezers based technology to accurately generate

105 ntinuous wave (CW) and femtosecond plasmonic optical tweezers, based on gold-coated black silicon.

106 Using optical tweezer-based single-molecule force measurement,

107 iving cells by combining micropatterning and optical tweezers-based active microrheology.

108 The application of holographic optical tweezers-based micromanipulation will enable nov

109 Here, we develop an optical tweezers-based single-molecule (SM) motility ass

110 y of the single-molecule characterization in optical tweezers but also clearly revealed mechanical fe

111 at low photon flux, while femtosecond-laser optical tweezers can probe the nonlinear optical propert

112 cular force spectroscopic approaches such as optical tweezers can track the pseudoknot's unfolding in

113 o resolve rotations during stepping, we used optical tweezers combined with an optical microprotracto

114 re we introduce Raman Tweezers (RTs), namely optical tweezers combined with Raman spectroscopy, as an

115 Using near-infrared optical tweezers combined with TIRF microscopy, we were

116 Low-power near-field nano-optical tweezers comprising plasmonic nanoantennas and p

117 Here we show that optical tweezer-controlled pulling of the A1 domain of V

118 energy, which is analogous to the well-known optical tweezers effect.

119 Microrheology using optical tweezers enabled us to measure local viscoelasti

120 that in the force range accessible in laser optical tweezer experiments there should be a switch in

121 an integrated approach using single molecule optical tweezer experiments, loop insertions, and steere

122 Here, we use single-molecule optical tweezers experiments and stochastic theory to sh

123 Optical tweezers experiments have shown that it requires

124 The results of the optical tweezers experiments highlight the complex natur

125 Single molecule optical tweezers experiments show that under intermediat

126 Based on force-clamp optical tweezers experiments we report here that, in a p

127 the packaging process compatible with recent optical-tweezers experiments.

128 elastic deformations match those obtained in optical-tweezers experiments.

129 we describe a single-molecule assay based on optical tweezers, fluorescence microscopy and microfluid

130 laser ablation unit for microsurgery and an optical tweezer for cell micromanipulation.

131 ce configuration also enables application of optical tweezers for controlled placement of atoms.

132 Using optical-tweezers force spectroscopy, we found that CS2 f

133 Optical tweezers has emerged as a powerful tool to study

134 Optical tweezers have become one of the primary weapons

135 s inherent in constructing a precision axial optical tweezers have been solved.

136 Optical tweezers have emerged as a powerful tool for the

137 Among the various tools available today, optical tweezers have recently seen great progress in te

138 Optical tweezers have revolutionized our understanding o

139 e coalescence of two droplets in holographic optical tweezers (HOT) and poke-and-flow experiments on

140 tweezers was the development of holographic optical tweezers (HOT) which enabled the independent man

141 Holographic optical tweezers (HOTs) enable the ability to freely con

142 id stain; (ii) capturing a single spore with optical tweezers; (iii) simultaneously measuring phase-c

143 Active microrheology measurements using optical tweezers in living cells reveal that the presenc

144 In order to adopt plasmonic optical tweezers in real-world applications, it is essen

145 Latex micrometric beads are manipulated by optical tweezers in the vicinity of an ultramicroelectro

146 We simulate RBC stretching tests by optical tweezers in three dimensions.

147 To demonstrate this, we use dual-trap optical tweezers, in combination with fluorescence micro

148 hough previous studies have established that optical tweezers induce photodamage in live cells, the e

149 y supercoiled DNA using a standard dual-trap optical tweezers instrument.

150 Optical tweezers integrated with Raman spectroscopy allo

151 show that immobilizing non-adherent cells by optical tweezers is sufficient to achieve optical resolu

152 Here we show how, using a mobile optical tweezer, it is possible to prepare and locally e

153 he assay is based on an instrument combining optical tweezers, light and fluorescence microscopy, and

154 In single-molecule laser optical tweezer (LOT) pulling experiments, a protein or

155 y used force spectroscopy techniques, namely optical tweezers, magnetic tweezers, and atomic force mi

156 Here, we present the results of optical tweezer measurements that compare the kinetic an

157 physical principles and practical aspects of optical tweezers measurements and discuss recent advance

158 Here, we use single-molecule optical tweezers measurements to compare translocation o

159 the motor mechanism we used single-molecule optical tweezers measurements to study the effect of mut

160 By combining single-molecule optical tweezers measurements with a quantitative mfold-

161 predictions of hygroscopicity, as well as to optical tweezers measurements, are presented, demonstrat

162 A dual optical tweezers method can hence be reliably used to as

163 We use optical tweezers microrheology and confocal microscopy t

164 We use optical tweezers microrheology and fluorescence microsco

165 In this study, we pioneered the use of optical tweezers microscopy to study Ab-capsule interact

166 Using a combination of optical tweezers, mutagenesis, and chemical cross-linkin

167 Optical tweezers offer precise control in the force rang

168 Using optical tweezers operated independently of three-dimensi

169 el were observed in the case of NMIIB-HMM in optical tweezers or TIRF/in vitro motility experiments.

170 Using optical tweezers (OT) and steered molecular dynamic simu

171 Using mechanical unfolding by optical tweezers (OT) and steered molecular dynamics (SM

172 we combine atomic force microscopy (AFM) and optical tweezers (OT) experiments to show that high mobi

173 scattering (LS) analysis of capsular PS and optical tweezers (OT) to explore the architecture of the

174 Optical tweezers (OTs) measure the force-dependent time-

175 meter-sized beads of glass held in air by an optical tweezer, over a wide range of pressures, and we

176 Our work expands the capabilities of optical tweezers platforms, and represents a new paradig

177 Bead probing with optical tweezers provides a new, nondestructive method t

178 Manipulation of individual molecules with optical tweezers provides a powerful means of interrogat

179 the potential of the integrated holographic optical tweezers-Raman technique to induce deformations

180 The manipulation of proteins with optical tweezers requires attaching molecular handles to

181 igital microfluidics, digital bioassays, and optical tweezers, resulting in a powerful dynamic microw

182 Force-extension experiments with optical tweezers revealed persistence lengths of 1.5 mum

183 Raman optical tweezers (ROT) as a label-free technique plays a

184 e-cell RNA sequencing (scRNA-seq) with Raman optical tweezers (ROT), a label-free single-cell identif

185 Using single-molecule optical tweezers, Sen et al. show that ClpX uses a coord

186 , we have developed a novel temperature-jump optical tweezers setup that changes the temperature loca

187 Using a dual-trap optical tweezers setup, we found the fusion speeds of fo

188 ent spatial directions, which may affect any optical tweezers setup.

189 ined in a, to our knowledge, novel dual-trap optical-tweezers setup that directly measures forces.

190 mmon source for these couplings in dual-trap optical-tweezers setups: the misalignment of traps and t

191 Both CD and single molecule studies using optical tweezers showed that the two quadruplexes in the

192 present the latest progress that has pushed optical tweezers' spatial and temporal resolution down t

193 with diabetic retinopathy (DR) using a dual optical tweezers stretching technique.

194 ere, we use single-molecule fluorescence and optical tweezers studies to elucidate the role of AAA4 i

195 teristics compared with the more established optical tweezers, such as higher trapping forces per uni

196 Using an optical tweezers system, isolated mammalian chromosomes

197 Using a cell-bead optical tweezers system, we obtained evidence for cell-m

198 ng and force measurements in a compact fiber optical tweezers system.

199 Here, using optical tweezers techniques, we demonstrate that S1 prom

200 uring invasion, and demonstrate the power of optical tweezers technologies in unraveling the blood-st

201 vector assembly requires a minimal number of optical tweezers that allow operations like chain elonga

202 Here, using optical tweezers that can simultaneously resolve two-pho

203 In this work, using novel magneto-optical tweezers that combine the nanometer resolution o

204 a combination of fluorescence microscopy and optical tweezers, that all three structures can exist, u

205 to address this question by measuring, with optical tweezers, the real-time replication kinetics of

206 ased P. falciparum merozoites, delivered via optical tweezers to a target erythrocyte, retain their a

207 We used optical tweezers to analyze the effect of jasplakinolide

208 the fiber based detection, we used the fiber optical tweezers to apply a force on a cell membrane and

209 to hundreds of microns by using holographic optical tweezers to apply pN forces to microparticles em

210 Using optical tweezers to apply tensile force to single domain

211 Using optical tweezers to apply tension across the RNA, we mea

212 Using optical tweezers to apply tension to single mRNA molecul

213 we use single-molecule force spectroscopy by optical tweezers to assess the folding and stability of

214 while monitoring DNA unwinding activity with optical tweezers to capture the entire sequence of prote

215 orescence microscopy, Raman spectroscopy and optical tweezers to characterize the germination of sing

216 To study this possibility, we used optical tweezers to determine and compare the structure

217 We use high-resolution optical tweezers to determine the effect of nucleotide a

218 We applied optical tweezers to directly measure single-molecule mec

219 In contrast to raster assembly that assigns optical tweezers to each particle, vector assembly requi

220 Here we use optical tweezers to examine force generation by single m

221 Here, we resolve this controversy by using optical tweezers to extend small 60-64 bp single DNA dup

222 uring its synthesis, we used high-resolution optical tweezers to follow in real time the co-transcrip

223 We used optical tweezers to follow the unwinding of double-stran

224 Here, we address these questions using optical tweezers to follow translation by individual rib

225 We demonstrate the use of optical tweezers to manipulate and mix droplets.

226 fluorescence resonance energy transfer with optical tweezers to measure human telomeric sequences un

227 We used optical tweezers to measure single DNA molecule elongati

228 Here, we used single-molecule optical tweezers to measure the assembly energy and kine

229 We used optical tweezers to measure the strength and attachment

230 contrast microscopy, Raman spectroscopy, and optical tweezers to monitor a variety of changes during

231 Here we use single-molecule optical tweezers to monitor misfolding reactions of the

232 Here, we used optical tweezers to observe in a cell-free reconstitutio

233 Using optical tweezers to perform microrheology measurements,

234 Key to this work is our use of optical tweezers to precisely position individual cells

235 on and proofreading, we used high-resolution optical tweezers to probe how DNA-duplex stability affec

236 hanism, we used single-molecule studies with optical tweezers to probe the kinetics of DNA-phenanthri

237 al. and Maillard et al., use single-molecule optical tweezers to show directly that these molecular m

238 Here we used optical tweezers to show that the free energy cost to fo

239 Here, we use optical tweezers to study how the holdase Hsp33 alters f

240 Here we employ optical tweezers to study individual invasion events for

241 Here, we use dual trap optical tweezers to study single yeast RNA polymerase II

242 Here, we used optical tweezers to study the folding behavior of indivi

243 e used single molecule force spectroscopy by optical tweezers to study the folding of calmodulin in t

244 antly, our study demonstrates the utility of optical tweezers to test a role for ligand endocytosis i

245 onstrate that polystyrene beads connected by optical tweezers to the ends of adherent filopodia of J7

246 nge of single-molecule force spectroscopy by optical tweezers to the microsecond range by fast sampli

247 Here, we used high-resolution optical tweezers to track the path of single budding yea

248 ing, which combines force and urea using the optical tweezers, together with traditional protein unfo

249 he folding and unfolding of T4 lysozyme with optical tweezers under a chemo-mechanical perturbation b

250 f the phage T4 gp17 motor by using dual-trap optical tweezers under different conditions of perturbat

251 Optical tweezers use the momentum of photons to trap and

252 A dual optical tweezers was made by splitting and recombining a

253 A dramatic advancement in optical tweezers was the development of holographic opti

254 of the rigidity of mucus and model gels with optical tweezers was used in this context to confirm suc

255 For example, using optical tweezers we bring two droplets, one containing a

256 Using optical tweezers we found that the power stroke sizes of

257 Using optical tweezers, we characterize the MT-binding strengt

258 Using high-resolution optical tweezers, we characterized their energies and tr

259 Using optical tweezers, we demonstrate that arrest of SecM-sta

260 Using optical tweezers, we find that isolated nuclei lacking i

261 Using high-resolution optical tweezers, we find that packaging occurs in incre

262 Using optical tweezers, we found that tensile force further in

263 Using optical tweezers, we found that the adhesion strength of

264 Using single-molecule optical tweezers, we have defined the steps leading to f

265 Using optical tweezers, we have dissected early folding events

266 Using optical tweezers, we investigated the mechanical unfoldi

267 Using optical tweezers, we measure A3G binding a single, long

268 Using optical tweezers, we measure the rates of unwinding and

269 Using optical tweezers, we measured the diffusion coefficient

270 Using optical tweezers, we probe pre-TCR bonding with pMHC at

271 Using optical tweezers, we probed the coupling dynamics betwee

272 ,000 times smaller than that in conventional optical tweezers, we rotate, translate, localize, and as

273 Using optical tweezers, we show that filopodial retraction occ

274 orce microscopy, and force spectroscopy with optical tweezers, we show that these DNA variants have b

275 Here, using optical tweezers, we tested the dynamic physical interac

276 dimers in a multiequilibria mixture, whereas optical tweezers were applied to monitor the (un)folding

277 In this paper, optical tweezers were implemented on a digital microflui

278 In this study, optical tweezers were used as a single-molecule force tr

279 esults was carried out by calibration of the optical tweezers when trapping microspheres with a diame

280 i.e., without microbead handles) in the dual optical tweezers where they were observed to adopt a "si

281 Here we consider FRs in dual-trap optical tweezers where two different forces (one per tra

282 ing "topological tweezers," an array of weak optical tweezers which strain the lattice by weakly pull

283 Axial optical tweezers, which apply force to a surface-tethere

284 These measurements were conducted using optical tweezers, which enabled high temporal and spatia

285 or the spatial position of a bead trapped in optical tweezers, which enables us to reconstruct its dy

286 y a ring of particles trapped in holographic optical tweezers, which form a flexible elastic wall.

287 prising two independent modules: holographic optical tweezers, which offer a versatile and precise wa

288 rorheological techniques such as holographic optical tweezers, which rely on expensive equipment and

289 e is based on fast, real-time control of 100 optical tweezers, which we use to arrange atoms in desir

290 nticipate that these high-resolution magneto-optical tweezers will be instrumental in studying the in

291 Here we integrate optical tweezers with cell biological and biochemical me

292 ts of rates and energy landscapes made using optical tweezers with estimates obtained from the same s

293 developed a single-molecule assay combining optical tweezers with fluorescence to monitor binding to

294 combines contactless levitation with aerosol optical tweezers with isotopic exchange (D2O/H2O) to mea

295 We have developed an approach combining optical tweezers with light-sheet microscopy to probe th

296 Optical tweezers with nanometer spatial and millisecond

297 Using optical tweezers with single base pair (bp) resolution,

298 A secondary structures using high-resolution optical tweezers with single-molecule fluorescence capab

299 Here, we used optical tweezers with single-molecule fluorescence to ob

300 single DNA hairpin molecule was monitored by optical tweezers within a yoctoliter volume.