ライフサイエンスコーパス: optimise

1 unction for which their phenotypes have been optimised.

2 indicates how future implementations can be optimised.

3 wer requirements if the wingbeats were fully optimised.

4 on the production of ester were studied and optimised.

5 a cell line where other conditions have been optimised.

6 ular components, the activity of each can be optimised.

7 rther benefits if use of these treatments is optimised.

8 and emulsifier, pH and ionic strength, were optimised.

9 Using an optimised (23)Na-MRI protocol with smaller voxel sizes a

10 echolamine function modulates the ability to optimise a meta-learning parameter (learning rate) as a

11 We developed and optimised a protocol for cleaning paediatric height and

12 t when our machine learning algorithm, which optimises a statistical model combining Principal Compon

13 cated image processing analysis routines and optimising a multivariate statistical machine learning a

14 plications for the design and engineering of optimised Ad-based therapeutics.

15 Optimising adherence is therefore important for preventi

16 to artificially regulate this environment to optimise agricultural productivity.

17 ozoan parasite Toxoplasma gondi and describe optimised analysis methods for small scale libraries.

18 n eligible for curative-intent radiotherapy, optimise and customise radiation doses to specific tumou

19 variability and heterogeneity of tumours to optimise and engineer anti-cancer therapies.

20 tion and deprescribing efforts are needed to optimise and unify the management of bronchiolitis.

21 cells and a double antibiotic selection was optimised and allowed the isolation of viable desired cl

22 rmance of the assay and the sensor was first optimised and characterised in pure buffer conditions gi

23 ng that the timing of decision making can be optimised and individualised.

24 hospital visit results in a bespoke orthosis optimised and personalised for each patient.

25 mental signals to ensure resource capture is optimised and unfavourable environments are avoided.

26 ory pathobionts in healthy cattle using qPCR optimised and validated to quantify Histophilus somni, M

27 method for their determination in wines was optimised and validated using the LC-IT platform.

28 Recommendations for optimising and advancing research on the health impacts

29 umour activity with the combination of an Fc-optimised anti-HER2 agent (margetuximab) along with anti

30 pment and implementation of interventions to optimise antibiotic use.

31 r results have wide-ranging implications for optimising antitrypanosomal drugs and averting cross-res

32 ced damage, trilaciclib has the potential to optimise antitumour activity while minimising myelotoxic

33 Here, we describe an optimised approach for detecting single RNA transcripts

34 Here, we describe an optimised approach for fibroblast isolation from human l

35 ession are needed to inform interventions to optimise ART delivery.

36 ) prophylaxis to expand donor options and an optimised ART strategy of avoiding pharmacoenhancers and

37 ecommendations for those wishing to maximise/optimise auxetic foam production.

38 ere randomly assigned (341 to delamanid plus optimised background regimen [delamanid group] and 170 t

39 en [delamanid group] and 170 to placebo plus optimised background regimen [placebo group]) and formed

40 erculosis to receive, in combination with an optimised background regimen developed according to WHO

41 d oral fostemsavir (600 mg twice a day) plus optimised background therapy from day 1.

42 men for 8 days, followed by fostemsavir plus optimised background therapy; or the non-randomised coho

43 nd that given the opportunity, tree crickets optimised baffle acoustics; they selected the best sized

44 chi method and metAFLP analysis were used to optimise barley regenerants towards maximum and minimum

45 However, in many cases it is necessary to optimise beliefs about sequences of states rather than j

46 tools to expedite engineering of strains for optimising biosynthetic pathways.

47 oton beams can be efficiently controlled and optimised by employing a recently developed helical coil

48 ion and solubility of hFGF21 were tested and optimised by fusing the protein with one of eight tags:

49 vonoids with high cyto-protective effect was optimised by response surface methodology (RSM).

50 on of total saponins from alfalfa leaves was optimised by the simultaneous maximization of the yield

51 The extraction step was optimised by using an experimental design.

52 Patients were randomly assigned to an optimise care dose of kVp - group A, n = 36; 18 men, 18

53 , deployed as a simple nomogram, can help to optimise care in women with epilepsy.

54 quality to be achieved in both groups, with optimised care dose for both protocols, and contrast vol

55 ained in this study can serve as a guide for optimising CED treatment regimens.

56 techniques developed here will be useful for optimising cell therapy in kidney diseases.

57 ives are reducing intracranial pressure, and optimising cerebral perfusion, while killing the bacteri

58 is sensor could potentially help validate or optimise cleaning practices for a given food manufacturi

59 re, pet food design tools are needed towards optimising cleaning efficacy.

60 rstanding and use of published literature to optimise clinical care, including the science of systema

61 e used to search for synthetic lethality and optimise combination protocol designs.

62 Adaptively Optimised Combination (AOC) yielded the maximum SNR impr

63 -income and middle-income countries (LMICs): optimised combination therapies for confirmed meningitis

64 The optimised composite ink was then successfully printed on

65 he functions of complementary materials with optimised compositions and morphologies.

66 Under an optimised condition, the LOD of our SERS-based muPAD was

67 ms to prevent additional brain damage and to optimise conditions for brain recovery.

68 l viability, function or proliferation under optimised conditions (5 MBq/mL, 60 min).

69 Optimised conditions allows determination of neonicotino

70 Under optimised conditions, extraction of spiked analytes from

71 Even under non-optimised conditions, high turnover numbers for coupled

72 Under optimised conditions, they could be used for histamine s

73 These focus on: (a) optimising crop primary productivity (e.g. nutrient opti

74 Using an optimised cutoff for this biomarker, sensitivity was 86%

75 ucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and beha

76 issue disaggregation on gene expression, and optimise data processing to improve clustering quality.

77 the coordination of SA and JA/ET pathways to optimise defences against (hemi)biotrophic and necrotrop

78 as prognostic markers due to development of optimised detection methods and increasing use of 3 T cl

79 viders to use the output of these devices to optimise diabetes management.

80 elieve that it is possible to accelerate and optimise diagnostic development through a five-pronged s

81 The optimised diets had up to 30% lower blue water footprint

82 Use of synthetic, codon-optimised DNA enabled overexpression of functional PfVIT

83 An evidence-based optimised dose regimen was constructed that would provid

84 ular events) to continue allopurinol (at the optimised dose) or start febuxostat at 80 mg/day, increa

85 chronic kidney disease who were selected to optimise efficacy and safety.

86 Many challenges exist to optimise efficacy, minimise toxicity, and broaden the ap

87 Future studies should optimise EHR-based HIV risk prediction tools and evaluat

88 stantial fundamental research is required to optimise electrode design for specific operating conditi

89 sfusions with hospice services are likely to optimise end-of-life care for patients with haematologic

90 mation transfer through the substrate whilst optimising energy efficiency over repeated cycles.

91 We present an optimised ex vivo mycobacterial growth inhibition assay

92 wer number of control nodes is presumably to optimise exploitation of specific sub-systems needed for

93 These findings provide promising pathways to optimise floral plantings to more effectively contribute

94 This potential was applied by optimising foamy virus vectors carrying the full-length

95 EAPP rollout strategy corresponds to a plan optimised for a slightly wetter climate compared to hist

96 sonication and centrifugation times were all optimised for analytes using engine-oil.

97 ussion of tuneable CD properties that can be optimised for applications in photocatalysis.

98 he preparation of truncated natural products optimised for biological activity.

99 rotein complexes have been evolutionarily co-optimised for correct function.

100 e, using genomic-scale datasets and analyses optimised for countering systematic error, we find stron

101 infrared camera surveys use multiple cameras optimised for different ranges offshore.

102 Indeed, gene expression can be optimised for health in older ages through manipulation

103 ool in food authentication that has not been optimised for honey analysis.

104 The culture conditions were optimised for maximum chitinase production recording up

105 a bioreactor vibration plate, calibrated and optimised for nanometre vibrations at 1 kHz, a power sup

106 gineered to integrate sophisticated features optimised for precision-targeting of a wide range of can

107 represent a move away from expensive systems optimised for single measurements, towards affordable an

108 ms where the surface morphology had not been optimised for smoothness, the topographical variation wa

109 A microwave-assisted extraction method was optimised for the recovery of bioactive compounds from C

110 ely used mutation calling algorithms are not optimised for the simultaneous analysis of multiple samp

111 Wheat ideotypes were optimised for yield in rainfed condition by using an evo

112 der to achieve sustainable development while optimising for well-being.

113 e period will generate further knowledge for optimising future vaccine design.

114 operative testing of anaemia, and methods of optimising haemoglobin concentrations in the context of

115 pregnancy who would benefit from support to optimise health before conception) in order to raise awa

116 (D240 antibody) immunohistochemistry (IHC), optimised high-resolution X-ray microfocus computed tomo

117 one or buprenorphine maintenance therapy, to optimise HIV outcomes.

118 To optimise HIV prevention and treatment goals in Ukraine,

119 te its utility to find tissue- and cell line-optimised housekeeping genes without any prior bias, tha

120 d to prioritise public health investments to optimise human development.

121 rs, clinicians, and scientists as a means to optimise human-machine interfaces.

122 ount and smoking status has the potential to optimise ICS use in clinical practice in patients with C

123 The setup was optimised in order to increase the volume of particle in

124 orine-doping and degree of the oxidation are optimised in tandem.

125 )-7-deaza-2'-deoxyadenosine triphosphate was optimised in terms of a compromise between maximum PCR e

126 Through the use of highly optimised, in-memory data structures and algorithms, Rea

127 Two parallel biosensors were designed and optimised independently, based on each bioreceptor.

128 up to 18% in three hours can be achieved by optimising inertial cavitation dose during ultrasonicati

129 n of evidence-based guidelines is crucial in optimising intervention use and improving quality of mat

130 To optimise its properties and exploit it for future memory

131 , we embraced that noise to develop the self-optimising Kohonen index network (SKiNET), and provide a

132 RNAseq is both sensitive and quantitative by optimising laboratory and bioinformatic variables using

133 ed in LC firing and noradrenaline release-to optimise learning rate, enabling large adjustments over

134 Our approach facilitates optimising measurement strategies and quantifying uncert

135 self-charging biosupercapacitor based on an optimised mediator- and membrane-free enzymatic glucose/

136 ion, the need for specific therapies besides optimised medical therapy can be determined.

137 ment in noise equivalent power compared with optimised mesa geometry SPADs.

138 In summary, our optimised method allows the usage of frozen human sample

139 The optimised method successfully characterised the presence

140 These resources and optimised methods enable facile and scalable genome edit

141 We validated the ability of these optimised methods to perform absolute quantification of

142 e. lipid extraction and FA methylation) when optimised methylation parameters (temperature, time, mil

143 The optimised mixed meso/microporous monoliths demonstrate T

144 or modelling muscle activation dynamics, and optimised model parameters using one data set.

145 nt canopies, emerge as a plastic response to optimise N utilisation for carbon assimilation.

146 ts in the targeted synthesis of functionally optimised 'non-natural' natural products.

147 ents, however, it is requisite to rigorously optimise oligonucleotide chemistries as well as chemical

148 es a simple yet highly sensitive platform to optimise oligonucleotide chemistries as well as chemical

149 Assay parameters were optimised on a set of 713 samples.

150 cs (PHCs) in southwestern Harare implemented optimised, opt-out PITC for all attendees aged 6-15 year

151 al treatment with amisulpride as part of the OPTiMiSE (Optimization of Treatment and Management of Sc

152 ration of these areas would be beneficial to optimise our interactions with them.

153 We employed a highly optimised ovine tracheal epithelial cell model to assess

154 Overall, our results suggest that optimising P fertiliser use is key to sustainable intens

155 ectable signatures in model dynamics and its optimised parameters.

156 The non-linear "Wilson" model that optimises parameters to all data set parts simultaneousl

157 and toxicity assessment and management, and optimised patient engagement across the cancer care cont

158 tion and more stringent cutoffs on Xpert HPV optimise performance characteristics of this assay for s

159 comes remains largely unknown, yet is key to optimising personalised treatment strategies.

160 olumn to minimise photo-oxidative stress and optimise photosynthetic efficiency.

161 oping effective automation for psychiatry to optimise physician treatment of individual patients.

162 We report an optimised pipeline for faecal host DNA analysis from the

163 vided by light and temperature cues helps to optimise plant body architecture and physiology.

164 cks both require explicit consideration when optimising policies to manage tropical carbon and biodiv

165 Optimising pore diameter and fraction in terms of broad-

166 k metrics and energetic terms to generate an optimised predictor.

167 The site of crosslinking of the optimised probe, as well as its ability to enrich member

168 The optimised procedure was scaled up to a half-litre batch.

169 need to target these cognitive functions to optimise prognosis.

170 t and Management of Schizophrenia in Europe (OPTiMiSE) programme, we conducted an RNA-Seq analysis on

171 These ECAPs are also used to optimise programming and deliver closed-loop spinal cord

172 Optimising protein solutions through experimental screen

173 For test development, samples from the optimised protocol (30 min standing time, 0 freeze-thaw)

174 iscriminatory metabolite biomarkers from the optimised protocol remained discriminatory between RRMS

175 usted odds ratio 8.52, 95% CI 3.98-18.24) or optimised provider-initiated testing and counselling (6.

176 ion (provider offered during consultations), optimised provider-initiated testing and counselling (wi

177 unselling group and 261 (14%) of 1837 in the optimised provider-initiated testing and counselling gro

178 ovider-initiated testing and counselling and optimised provider-initiated testing and counselling gro

179 sting and counselling group, and 1837 in the optimised provider-initiated testing and counselling gro

180 e data require quality control assessment to optimise quality for clinical management and for robust

181 analytical approximation of NTCP could help optimise radiotherapy planning, for example by estimatin

182 RETATION: TRF-budesonide 16 mg/day, added to optimised RAS blockade, reduced proteinuria in patients

183 P and mercaptophenylacetic acid (MPAA) in an optimised reaction environment to achieve an efficient l

184 alised Risk assessment in Febrile illness to Optimise Real-life Management across the European Union)

185 ategy represents an alternative approach for optimising regorafenib dosing with comparable activity a

186 discovery in the Psoriasis Stratification to Optimise Relevant Therapy (i.e., PSORT) study, we evalua

187 phropathy and persistent proteinuria despite optimised renin-angiotensin system (RAS) blockade.

188 493 participants entered a 3 month run-in to optimise risk factor and glycaemic control (single-blind

189 were analysed for nitrate and nitrite by an optimised RP-HPLC technique with isocratic elution using

190 ial risks and highlights ongoing research to optimise safe and effective delivery of vectors into the

191 lar overall water splitting by combining the optimised Sb(2)Se(3) photocathode with a BiVO(4) photoan

192 ted gastrointestinal digestion using a newly optimised SEC-ICP-MS method.

193 Under optimised sensing conditions, the immunosensor demonstra

194 Under optimised sensing conditions, the single stranded CCCVd

195 desynchronization and global arousal jointly optimise sensory processing and performance.

196 urden of CVD must be better characterised to optimise service provision and permit workforce planning

197 als with time-to-event endpoints and provide optimised settings for future trials.

198 We find that this choice optimises short-term prediction accuracy and can rapidly

199 tracellular GABA, brain network activity can optimise signal integration rules in local excitatory ci

200 signed patients (1:1) to receive 3 months of optimised single-lead DBS-either VIM or VO.

201 The InGaZnO TFTs with the optimised SiO2 electrolyte also showed good air stabilit

202 ll enable us to gather insights critical for optimising social encounters between humans and robots.

203 C skulls that could be used in the future to optimise spring surgery.

204 s with prolonged disorders of consciousness, optimised stimulation parameters, alternative drugs, or

205 ent interactions and can be out performed by optimised strategies with longer memory.

206 r Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, noninferior

207 Understanding the barriers to optimising survival can help improve childhood cancer ou

208 Molecular dynamics is used to optimise that prediction allowing, for the first time, t

209 population-based pharmacokinetic approach to optimise the antimalarial treatment regimen for piperaqu

210 Response Surface Methodology was employed to optimise the combined effects of different steam blanchi

211 evolution robotic platform that can reliably optimise the conditions to produce gold-nanoparticles ov

212 This study suggests there is scope to optimise the contribution of primary care, community car

213 Feasibility work is recommended to optimise the design and implementation of randomised con

214 sed consensus modelling to understand how to optimise the effects of mass drug administration in area

215 the composition of the thylakoid membrane to optimise the efficiency of electron transfer to the prev

216 The aim of this study is to optimise the image quality of computed tomography (CT) s

217 various synthetic promoter designs that can optimise the inorganic phosphate intake in E. coli.

218 to validate the efficiency of extraction and optimise the liquid extraction procedure for anthocyanin

219 tudies to use the approach described here to optimise the management of sagittal craniosynostosis.

220 otential to predict the calvarial growth and optimise the management of this condition.

221 ow these effects are utilised by the cell to optimise the outcome of protein biosynthesis.

222 es through training and logistic support can optimise the outcomes of managing CBDS.

223 how that reinforcement learning can directly optimise the output of a co-culture bioprocess.

224 ffects of manufacturing imperfections and to optimise the performance of apparatus.

225 We aimed to study and optimise the performance of two non-invasive indices for

226 dividual's potential, minimise barriers, and optimise the person-environment fit.

227 e partial least squares regression method to optimise the PLR extract with highest cyto-protective ac

228 he monoliths' macrostructure and use this to optimise the pore-size distribution for gas uptake.

229 ive research to be appropriately powered and optimise the potential for detecting treatment effects.

230 s, these variabilities could be exploited to optimise the role of gas hydrates.

231 Modifications to the substrate surface optimise the seeding and growth processes for the fabric

232 e deployed molecular dynamics simulations to optimise the selection of crosslinking compounds that ov

233 To efficiently optimise the system, we develop the Optometrist Algorith

234 urately simulate the electronic transport to optimise the technology but also suggest that 1D effects

235 e how varying core processing parameters can optimise the test-retest reliability of EEG connectivity

236 development of next-generation inhibitors to optimise the therapeutic index, overcome drug resistance

237 e more accurate sample size calculations and optimise the use of their available resources.

238 We have optimised the IGNIS kit to quantify APO-F as a NAFLD bio

239 We subsequently developed an algorithm that optimised the reliability of a T(skin)-derived estimate

240 We optimised the technique to study the effects of frataxin

241 Optimising the conduct of clinical trials for diffuse in

242 This study will help optimising the design of this new technology for the sel

243 Future trials should be based on optimising the dose and schedule, perhaps combined with

244 the possibility of an in silico approach to optimising the drug release profile and ultimately the e

245 epresents a novel tool for understanding and optimising the health efficacy of plant extracts.

246 ontrol of inertial cavitation is critical in optimising the high yield sonication-assisted aqueous li

247 good mechanical stability is challenging, as optimising the latter requires compromises regarding the

248 By optimising the mode coupling effect of a seven core mult

249 We hence suggest optimising the parent Mott state as a strategy for enhan

250 An example of such a challenge is optimising the performance of plasma fusion experiments.

251 ent, but both more accurately estimating and optimising the potential HIV prevention effects of unive

252 cromasking issues from the aluminium mask by optimising the proportion of O(2) in the plasma and intr

253 features can be introduced to the pattern by optimising the sphere dimensions and exposure conditions

254 mpedance can be matched to the free space by optimising the surface resistance of the thin lossy meta

255 animal feeding, are likely envisaged, while optimising the use of green haulm.

256 re expected to follow the spring snowmelt to optimise their arrival time and select for snow-free are

257 dress clinical and operational challenges to optimise their global deployment.

258 t multi-parent populations should feature to optimise their use as powerful community resources for c

259 f action require further characterisation to optimise their utilisation for tomato improvement.

260 such as sorghum, pearl millet and wheat have optimised their flower opening during cooler early morni

261 Optimising their use is crucial in reducing the burden o

262 hic lateral sclerosis (ALS) are limited, and optimising their use is vital for efficient drug develop

263 ss these previous efforts of self-treatment, optimise them, and strategically use the increasing list

264 a with the aim of reducing diagnostic delay, optimising therapeutic trial design and catalysing the d

265 findings have implications for selecting and optimising these enzymes for galactomannandegradation.

266 in albumin-based drug designs engineered to optimise this process.

267 ced through CRISPR-knock in, with the aim of optimising this approach for single molecule imaging.

268 d in vivo, the radioligands still need to be optimised to achieve higher tumour-to-background ratios

269 cell and innate immunity pathways have to be optimised to boost the efficacy and immune memory of pro

270 The device was optimised to detect thrombin activities in serum, achiev

271 gn of an optofluidic waveguide system can be optimised to enable simultaneous in-situ Raman spectrosc

272 nance, both study design and scale have been optimised to enable statistical inferences to be drawn.

273 idering how the deposition parameters can be optimised to ensure that the distribution of pores is ta

274 l symmetries to produce coils simultaneously optimised to generate homogenous fields and gradients.

275 ltration of Cyclopia genistoides extract was optimised to increase its benzophenone and xanthone cont

276 y loss so that experimental protocols can be optimised to meet the required standards.

277 We show that with model hyperparameters optimised to minimise cross validation error, ten method

278 y crosslinked with beta-glycerophosphate, is optimised to obtain sol/gel transition at physiological

279 f fibres within and underneath the cortex is optimised to support the convergence of different levels

280 Thus, the combination of a highly optimised topical triazole with oral triazoles potential

281 lead-in phase in which allopurinol dose was optimised towards achieving a serum urate concentration

282 requires well functioning systems of care to optimise treatment and improve patient outcomes.

283 g randomised studies will continue to aim to optimise treatment for high-risk neuroblastoma.

284 To optimise treatment of low bone density in women with epi

285 to reduce the differences in management and optimise treatment strategies.

286 DESIGN, SETTING, AND PARTICIPANTS: The Optimising Treatment for Mild Systolic Hypertension in t

287 act as signals that shape 3D root growth to optimise uptake.

288 Further investigation is needed to optimise use of advanced molecular imaging techniques an

289 collaborative, multidisciplinary approach to optimise use of antibiotics.

290 ormation on enzyme efficiency with regard to optimising use of available energy, a factor that would

291 Enzymatic hydrolysis of hemicellulose was optimised using response surface methodology, to obtain

292 Compound enrichment was subsequently optimised using the 10 kDa RC membrane and tangential fl

293 hree most significant variables were further optimised using the CCD.

294 i compounds from Labeo rohita head (LRH) was optimised using the combination of fractional factorial

295 Digestion of IGNIS prime peptides was optimised using trypsin and SMART Digest.

296 Further work is required to optimise vaccine regimens for younger seronegative camel

297 We show that more highly monomeric and codon optimised variants of mEos result in improved expression

298 energy that suggests forest mammals further optimise vocal communication according to their high fre

299 -governmental organisations are critical for optimising VR services, especially as rates of diseases

300 Here, we use SCRaMbLE to optimise yeast strains engineered to produce the triterp