ライフサイエンスコーパス: optimize

1 sis, protein extraction from FFPE tissue was optimized.

2 es Method for products of Plant Origin) were optimized.

3 ell as flow rate (0.6-0.75 mL min(-1)), were optimized.

4 jection volume were individually studied and optimized.

5 ction efficiency of cobalt were examined and optimized.

6 DC stability and hence needs to be carefully optimized.

7 thods effecting experimental parameters were optimized.

8 extraction efficiency of the copolymer were optimized.

9 , volume of reagents, and sample volume were optimized.

10 The optimized 2D-DIA method allowed for improved identificat

11 etrics to assess response to therapy, and we optimized a preclinical PERCIST paradigm to complement c

12 We optimized a protocol to generate choroid plexus organoid

13 human Purkinje cell (PC) differentiation, we optimized a protocol to generate human pluripotent stem

14 ed on contiguous (intertag distance <=6 mm), optimized (Ablation Index >550 anteriorly and >400 poste

15 o clinical trial design allows clinicians to optimize administration of TKIs before chemoradiotherapy

16 oved radiotherapeutic agents that combine an optimized affinity-modifying group and optimized albumin

17 ne an optimized affinity-modifying group and optimized albumin binders to maximize the tumor-to-kidne

18 Compound A and its optimized analogs also improved viability and function i

19 bination with mathematical modeling can help optimize and guide the design of clinical trials.

20 of anthocyanins from jabuticaba epicarp were optimized and the colouring potential of the developed e

21 oth cooling and image acquisition times were optimized and the images obtained with AT were compared

22 aking algorithm, can be readily envisaged in optimizing and understanding a broad range of systems in

23 genome editing enzymes themselves need to be optimized, and challenges regarding their editing effici

24 trometry (MBS-MS/MS) assay was developed and optimized, and its performance was characterized for the

25 et flow speed and desorption temperature are optimized, and reproducibility is demonstrated between r

26 s (PK) at infection sites hinders efforts to optimize antimicrobial dosing and shorten TB treatments(

27 pha/beta and IFN-gamma signaling pathways to optimize antiviral IFN-gamma activity.

28 currents that reach to 1.7 mA cm(-2) with an optimized, applied bias photon-to-current efficiency of

29 ning therapies with targeted treatment as an optimized approach in the future.

30 timize dose reporting, and future desired or optimized approaches for novel emerging radionuclides an

31 zoic acid or benzaldehyde can be selectively optimized as the main product.

32 We validate our optimized AsCas12a toolkit by screening for synthetic le

33 The optimized assay sensitively identified small DNA regions

34 exhibit chromatic behavior and are typically optimized at discrete spectral frequencies.

35 Transmission is optimized at intermediate temperatures (23-26 degrees C)

36 xture introduced to the mass spectrometer to optimize atmospheric conditions.

37 ays, followed by open-label fostemsavir plus optimized background therapy (randomized cohort).

38 We integrated an optimized bioinformatics pipeline with high-resolution m

39 Interventions to optimize blood culture (BCx) practices in adult inpatien

40 mited regime of growth kinetics based on the optimized BNNT synthesis condition afforded the control

41 Several compositions of sHDL were tested to optimize both T1317 encapsulation efficiency and ability

42 parameters of the extraction procedure were optimized by altering one parameter while keeping the ot

43 Se-NADES extraction was optimized by an experimental design.

44 Effective parameters were optimized by central composite design.

45 ptasensors was determined, and their MDL was optimized by controlling the diameter of the CPNTs owing

46 the new cnCV with standard nCV, Elastic Net optimized by cross-validation, differential privacy and

47 ped with a vector in the 2-position that was optimized by structure-guided compound design.

48 ver, this SRD ranking value is automatically optimized by using a receiver operator characteristic (R

49 macokinetic-pharmacodynamic relationships to optimize candidate selection through discovery and trans

50 markers of risk and even future targets for optimizing cardiovascular health.

51 Here, we describe an optimized Cas9-AAV6-based genome editing tool platform f

52 ten met with a largely empirical approach to optimizing catalyst structure and reaction conditions.

53 The optimized CBS workflow allows for rapid and high-through

54 lular signaling in EBV-infected B cells that optimizes cell survival and proliferation, setting the s

55 Optimized-Cell-MAP further successfully applies to the s

56 ations caused by environmental stress, while optimizing cellular fitness.

57 filtering may provide an efficient means of optimizing central visual processing and perception acro

58 The optimized chemical modifications of adenine base editor

59 This Article outlines the optimized chemical synthesis and preliminary biochemical

60 A self-optimizing chemometrics method facilitates scientists to

61 The computational platform developed allows optimizing chemotherapy protocols, within admissible lim

62 Under the optimized circumstance best voltammetric responses were

63 We optimized classification models for preoperative Compute

64 t clear which types of features are best for optimizing classification performance and which algorith

65 Early detection of RSV can optimize clinical management and minimize use of antibio

66 In addition, this method could be used to optimize clinical trials.

67 approaches in informing the 'next steps' to optimize cognitive and emotional health in developing ch

68 Microcapsules obtained using the optimized combination of independent variables was found

69 of the encapsulated material obtained using optimized combinations of independent variable were foun

70 The resulting optimized compounds had much improved physicochemical pr

71 At an optimized condition, the developed sensor exhibits excel

72 Using this system, we screened for optimized conditions to stimulate increases in Oct-4 and

73 The optimized conditions were used to create monoliths bound

74 Under the optimized conditions, the calibration curve of ketamine

75 Under optimized conditions, the working range, limit of detect

76 Using the optimized conditions, we were able to reliably identify

77 hort residence time of several minutes under optimized conditions.

78 owed a positive BAT with ALX, but only under optimized conditions.

79 capping with aldehyde can be achieved under optimized conditions.

80 models, selection of a minimum norm solution optimizes cross-validation leave-one-out stability and t

81 FAAS was improved upon by 67 folds using the optimized DES-LPME-SQT-FAAS method.

82 Results show that the performance of our optimized designs not only surpasses that of the gyroid

83 gand-binding and activity-based assays under optimized detergent conditions can support selection of

84 By simultaneously optimizing device geometry, driving parameters, and mate

85 In order to optimize diagnosis and treatment of tree pollen allergy,

86 ally, be tuned by experience or evolution to optimize discrimination of particular odorants.SIGNIFICA

87 Optimized DNA probes demonstrated high sensitivity with

88 We optimized DoMY-Seq by taking advantage of the well-descr

89 als, strategies under development that would optimize dose reporting, and future desired or optimized

90 Optimizing dose and schedule to maintain BR dose intensi

91 herapy by virus-specific T cell levels might optimize dosing of immunosuppressants.

92 Thus, Bf-ETFs may optimize electron transfer efficiency by enabling direct

93 ostatic potential (ESP) surfaces in order to optimize electrostatic complementarity is a key activity

94 Normothermic machine perfusion (NMP) enables optimized ex-vivo preservation of a donor liver in a nor

95 Under optimized experimental parameters by factorial design, t

96 Under the optimized extraction conditions, sixteen phenolic compou

97 ing graft survival to 3 months, the ASM will optimize eye banking and open up new perspectives in exp

98 regulated by acyl-CoA thioester binding that optimizes fatty acid (FA) metabolism in response to envi

99 ate and health damages, comparing portfolios optimized for benefits to climate alone or both health a

100 lectron microscopic connectomics techniques, optimized for disease analysis, to study the retina from

101 asingly specified ways, they can begin to be optimized for drug delivery in a more personalized manne

102 The evolutionary parameters optimized for each patient indicated substantial interpa

103 erial genomes are generally considered to be optimized for efficient growth and rapid adaptation, non

104 potentials of the active site cofactors are optimized for fast elimination of the toxic NO molecules

105 arly for methylated histone marks but is not optimized for H3K27ac profiling.

106 types, and most developed to date have been optimized for individual tumor types.

107 rmore show that the LUXendin backbone can be optimized for intravital two-photon imaging by installin

108 parse neural network model (DNN-GFS) that is optimized for neoantigen prioritization.

109 The first method is optimized for probe-free applications: Domains are direc

110 algorithm that utilizes a learned dictionary optimized for sparse inference on a D-Wave quantum annea

111 ctivity, bryostatin 1 is neither evolved nor optimized for the treatment of human disease.

112 D-19 vaccine development and our approach to optimizing for safety and efficacy.

113 utionary information and an energy landscape optimized force field (AWSEM), we predict atomic-scale s

114 Darwinian evolution enables them to approach optimized functionality (self-organized criticality).

115 aturity currently and formulate questions to optimize future care.

116 hese data provide a foundation from which to optimize future messenger RNA vaccination studies agains

117 to describe cases of vaccine failures and to optimize future vaccination recommendations.

118 Optimized geometries for the substituted ortho-benzyne a

119 Such effects impact optimized geometries, molecular vibrational frequencies,

120 ay between a streamlined plant body plan and optimized growth.

121 caused by the shot-to-shot energy jitter, an optimized gun phase yields only a mild reduction of the

122 The optimized hardware and method setup resulted in high-thr

123 ings may inform rapid response strategies to optimize health care delivery in parts of the world who

124 geries can allow clinicians to manage it and optimize hemoglobin level, making patients better prepar

125 ologous transfusion techniques and agents to optimize hemostasis are used during surgery and in the i

126 improves a woman's capacity to function and optimizes her mental and reproductive health.

127 In this study, we describe an optimized high-throughput proof-of-principle method for

128 mber and duration of design cycles needed to optimize hit or lead compounds into high-quality chemica

129 trating the localization of immune cells, to optimize host defence.

130 adeno-associated viral vector encoding codon-optimized human RPGR (AAV8-coRPGR), meeting the pre-spec

131 unresolved conduction pathways, crucial for optimizing hybrid perovskites for various optoelectronic

132 porous membranes as the support, so that it optimizes hydrodynamics while maintaining even fluxes.

133 nd pro-death decision node can be applied to optimize immune checkpoint inhibitor therapy for cancer

134 DWI and single-shot DWI sequences were first optimized in breast phantoms and then performed in a gro

135 p the layer in these ultra-black species are optimized in size and shape to minimize reflectance.

136 n and therefore, dosing interval needs to be optimized in the cohort of short-term responders.

137 Each studied parameter was optimized individually.

138 se of an automated decision support tool for optimizing insulin pump settings was non-inferior to int

139 precisely delineate the best strategies for optimizing invasive mechanical ventilation in this patie

140 e efficiency of strain screening and culture optimizing is usually quite low.

141 es rationally-that is, it takes actions that optimize its subjective reward according to its understa

142 he role of metabolic network architecture in optimizing its function.

143 For the optimized LC-MS/MS method described herein, we applied t

144 that this group may be less physiologically optimized leading to cardiac risks.

145 idneys, and a treatment having 4 cycles with optimized ligand amount and activity.

146 Accordingly, we developed spectrally optimized light using programmable LED arrays (PLA)s to

147 We further optimized lipidoid structures by constructing and screen

148 to determine whether early interventions to optimize LVSWI can improve outcomes in the CICU setting.

149 Simultaneously optimizing many design parameters in time-consuming expe

150 eral orders of magnitude more efficient than optimized matrix-based methods in terms of both run time

151 Surgeons need to optimize mental health assessment and services in the pr

152 Finally, we report a pharmacokinetic-optimized, metabolically stable derivative that induced

153 The final optimized method uses salt-assisted liquid-liquid extrac

154 The optimized method was validated according to authorities'

155 lapping transcriptomes, we have developed an optimized method, TIF-Seq2, able to sequence simultaneou

156 ition with a risk-averse opponent is key for optimizing motor decision-making.

157 ktop computer to the data stream and inserts optimized MS2 and MS3 scans in real time based on an app

158 s a two-fold tumor size decrease compared to optimizing nanoparticles without this consideration.

159 ure, on neuro-axonal injury, is paramount to optimize neuroprotective strategy in MS.

160 We developed a modeling approach to optimize NG/CT screening strategy in MSM.

161 s medicinal chemistry efforts that desire to optimize Nurr1-binding ligands.

162 We optimized one-pot, lyophilized, isothermal assays with a

163 rse episodes, even though the population was optimized only based on control data and in vitro drug t

164 We utilized an optimized orthotopic murine osteosarcoma model and human

165 findings highlight how temporal predictions optimize our interaction with unfolding sensory events.S

166 knowledge will become ever more important to optimize our patients' cardiovascular outcomes.

167 l research is needed to improve the care and optimize outcomes for both patients with and without cor

168 Dedicated expertise is needed to optimize outcomes for this population.

169 cirrhosis during pregnancy and postpartum to optimize outcomes.

170 SFE-CO(2) at optimized parameters yielded 11.8 g/100 g of lipophilic

171 of the eight ARBs was then docked, using ARB-optimized parameters, to each polymorphic AT1R (n = 6).

172 However, the field application is far from optimized, particularly for treatments at-or close to-th

173 d stronger national guidelines are needed to optimize patient selection for colectomy.

174 tching likely provides a general strategy to optimize perceptual processes.

175 study cytotoxic T lymphocyte biology and to optimize personalized immunotherapy in cancer treatment.

176 Variants of the orbital-optimized perturbation theory (NEO-OOMP2) method achieve

177 extraction and precipitation of protein were optimized - pH 4 and 12, respectively; and flour-solvent

178 the theory provides a universal guidance for optimizing phase transforming materials.

179 t illumination times were easily screened to optimize photodynamic effect.

180 tratification have traditionally centered on optimizing physical health.

181 developed against IFN-gamma and provided an optimized, physiologically relevant detection limit of 1

182 ssess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolys

183 Our findings offer practical guidance for optimizing platform and software selection when designin

184 While the optimized policy can adjust its parameters to outperform

185 tudies, the methodology for constructing and optimizing predictive signatures has been less prominent

186 e published literature and our experience to optimize procedures to obtain an accurate diagnosis and

187 ions of nDsbD with its partners resulting in optimized protein function.

188 Combining optimized proteoliposome isolation, cryo-sample preparat

189 Released O-glycans were purified by an optimized protocol to eliminate interference from small

190 Optimized protocols were successfully applied to experim

191 ofound alterations that must be addressed to optimize quality of life.

192 This study aims to optimize Raman spectral imaging for the identification o

193 ical trials remains a significant barrier to optimizing real-world outcomes for patients with nAMD.

194 The optimized recognition and degradation protocols were fou

195 ed antiretroviral susceptibility received an optimized regimen and were randomized to omit or add NRT

196 Regular linear or optimized regression and ANN models were built using tra

197 It was based on the optimized regression model with standard-sample bracketi

198 In practice, much work remains to optimize reliable online separation methods that are com

199 o <75 mL per min per 1.73 m(2), treated with optimized renin-angiotensin system blockade.

200 approach based on the assumption that plants optimize resource investment coordinating with environme

201 f CTL019 with intrapatient dose modification optimizes safety without compromising efficacy in adults

202 Under optimized SBSE conditions, eight different cannabis infl

203 of strategies will probably be necessary to optimize SCI treatment.

204 FASPR for fast and accurate PSCP by using an optimized scoring function in combination with a determi

205 We introduce a methodology for optimizing screening, assessing potential risks, and qua

206 ng target for rotational stocking systems to optimize sheep nutrition on pastures.

207 enome (including the X chromosome), using an optimized single-cell high-throughput chromosome conform

208 ect is inferring the reward distribution (to optimize some process), they will rarely agree in finite

209 odulation (PAM) fluorometry, showed that the optimized spectrum from the PLA gave an increase of 72%

210 Leveraging phenolic complexation to optimize starch functionality and digestibility is restr

211 to prevent nonadherence may be necessary to optimize stroke prevention.

212 3D laparoscopic display technique optimizes surgical performance compared to the 4K techni

213 rate of unnecessary invasive procedures and optimize surveillance regimens are needed.Objectives: To

214 tive dosing or timing treatment schedules to optimize synergism between drugs.

215 Under optimized temperature, NTU-65 adsorbed a large amount of

216 eaningful parameters that can be utilized to optimize the assay and enable quantification without sta

217 central composite design was implemented to optimize the derivatization temperature and extraction t

218 g FADS genetic variation may be necessary to optimize the design of future clinical studies with GLA-

219 um vacancies within the delithiated LiNiO(2) optimize the electronic structure of the surface NiOOH t

220 ally modifying these components), as well as optimize the large-scale production of AAV.

221 Clinical Outcomes Scores (COS) were used to optimize the MMS for biological and clinical relevance a

222 rating and balancing different ocean uses to optimize the overall ocean economy.

223 of multiple types of molecules allows us to optimize the properties of combination drug and imaging

224 mechanisms against network fracture that can optimize the strength of biological tissues.

225 We sought to optimize the synthesis of MH microneedles (MHMs) while m

226 of the continuous iteration of the model to optimize the target prediction - a process called 'end-t

227 ighly effective molecular design strategy to optimize the thermoelectric performance of conjugated po

228 ariatric surgery in this population can help optimize the transplant candidacy of patients with obesi

229 erapeutics in MS, and proposes strategies to optimize the use of existing anti-B-cell treatments and

230 This system could optimize the use of surveillance colonoscopy.

231 are costly and require rigorous planning to optimize the value of the information obtained.

232 compressed binary matrix representation, and optimized the algorithm for parallel execution on an NVI

233 ly, we predicted a squat-to-stand motion and optimized the stiffness of an assistive device placed at

234 damental question of how the phagocytic cell optimizes the acidification process to prevail.

235 of p261C and the three noncatalytic subunits optimizes the dual enzymatic activities of the catalytic

236 n vacancies and exposes more W active sites, optimizes the nitrogen adsorption energy, and facilitate

237 ly, the main role of chemical doping lies in optimizing the carrier concentration, but there can pote

238 assifier to use followed by the challenge of optimizing the chosen classifier (identifying the best t

239 f molecular marked whole laryngeal cancer by optimizing the currently available techniques.

240 lights the significance of understanding and optimizing the effects of liposomal nanoparticle design

241 Optimizing the feedbacks that shape chemical interaction

242 g of photosynthate into starch in the light, optimizing the fraction of assimilated carbon that can b

243 Here, by optimizing the modulation geometry and post-processing a

244 We tested whether optimizing the neonate's microbiome through maternal pro

245 Optimizing the nitrogen (N) input is crucial to achievin

246 Optimizing the perception of external cues and regulatin

247 Despite their immense contribution in optimizing the prognostic and therapeutic modalities, bi

248 Therefore, optimizing the protein import apparatus of plastids, des

249 lar hypoxia and absorption atelectasis, thus optimizing the residual lung function.

250 ZIKV NS1 could be significantly enhanced by optimizing the signal peptide.

251 r LRH-1 agonist and identify a potential for optimizing the SS-RJW100 scaffold for antagonist design.

252 can increase AAV transduction efficiency (by optimizing the transgene cassette), vector tropism (usin

253 ving global malaria eradication will require optimizing the transmission-reducing potential of all av

254 This effect is mitigated by optimizing the vaporization temperature, droplet size ra

255 perceive environmental light conditions and optimize their growth and development accordingly by reg

256 Plants optimize their growth and survival through highly integr

257 ponse, DCs undergo a maturation process that optimizes their ability to efficiently prime naive T cel

258 ten present themselves to medicinal chemists optimizing their compounds for candidate selection: (1)

259 ical mechanisms, and to assist clinicians in optimizing therapeutic choice in patients with sleep dis

260 The optimized thermal annealing temperature window and prefe

261 is particularly helpful in understanding and optimizing thermoelectric systems.

262 ntal understanding of film formation, key to optimizing these devices, is lacking.

263 Due to optimized thickness and optical properties of ITO film,

264 bservations encourage the rational design of optimized ThyX inhibitors that ultimately may serve as a

265 The pillar arena geometry was optimized to accommodate the growing body size during cu

266 slurry density (25 g/mL) were systematically optimized to achieve 80-99% leaching efficiencies of Ni,

267 separation and MS detection conditions were optimized to achieve fast, efficient, selective, and sen

268 tch spacing, and powder layer thickness were optimized to achieve the best possible metallurgical bon

269 The structure of each antenna is optimized to act both as the collector of the infrared e

270 The compound was optimized to afford a dimeric molecule that binds the Di

271 A synthetic small molecule optimized to bind the TAR GS also partially stabilized t

272 olymerization cycle and adsorption time, are optimized to improve the IMI sensing performance of the

273 how ICU interprofessional team rounds can be optimized to increase ICU Liberation adherence.

274 The device design is optimized to make all fluid particles interact with filt

275 The emission spectrum from the QDs was optimized to match the highest quantum efficiency region

276 d, new reaction conditions were successfully optimized to provide the elusive anti diastereomer by in

277 Likewise, feeding protocols were optimized to recapitulate longevity outcomes typical of

278 p learning architectures to characterize and optimize toeholds.

279 Using this optimized toolbox, we demonstrate robust reversible repo

280 data, improved feature design in DeepMSA and optimized training by the residual neural networks.

281 tcomes in pediatric UC, which may be used to optimize treatment algorithms.

282 Therefore, optimized treatment often requires drug combinations (ra

283 fusion and receptor density for standard and optimized treatments.

284 The extensively optimized UCNP-LF assay is as simple as the conventional

285 action of cashew apple juice was modeled and optimized using a multi-layer artificial neural network

286 The developed method was optimized using a multivariate approach providing LOQ va

287 The evolutionary model was optimized using a nonlinear mixed effect (NLME) method b

288 ganic framework (MOF) synthetic route can be optimized using an in situ monitoring apparatus designed

289 me, sample volume and amount of sorbent were optimized using central composite design (CCD) methodolo

290 combination of different areas thickness was optimized using chips with two areas for single analyte

291 The coupling reaction was optimized using CuI and low catalyst loading (down to 5

292 The factors affecting the SPE method were optimized using DOE tools.

293 high segregating capacity were extracted and optimized using feature selection algorithm and machine

294 parameters (e.g. time, solvent volume) were optimized using response surface methodology (RSM) and a

295 ss: buffer ratio (R), and pressure (P), were optimized using Response Surface Methodology (RSM).

296 ochemical properties than compound 1 and was optimized using structural information to achieve improv

297 ck nanoparticle-containing paper strips were optimized using this approach.

298 is for different vaccine candidates, matches optimized vaccine inserts, being identical to an ancestr

299 hodology based on Ant Colony Optimization to optimize variable selection and model fitting to predict

300 combinability and introgression may further optimize yield and improve sustainability.