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1 elf-esteem was associated with the bilateral orbitofrontal activity during evaluation of one's own po
2 ficantly decreased mid-insula, amygdala, and orbitofrontal activity while attending to interoceptive
4 theses, we recorded neuronal activity in the orbitofrontal and anterior cingulate cortex of two monke
6 BPD exhibited higher activity in the lateral orbitofrontal and dorsolateral prefrontal cortices compa
7 oral and orbitofrontal cortices, and between orbitofrontal and nucleus accumbens, predict individual
12 ociated with significant hypoconnectivity in orbitofrontal and ventromedial prefrontal cortical-stria
13 eferentially starts in the precuneus, medial orbitofrontal, and posterior cingulate cortices, i.e., s
15 Disinhibition is related to right ATL and orbitofrontal atrophy, and face recognition to right ATL
17 The reduced functional connectivity in left orbitofrontal-both thalamic regions with suicidal ideati
18 hickness asymmetry in mostly medial frontal, orbitofrontal, cingulate and inferior temporal areas, an
19 l operculum, supramarginal gyrus, and medial orbitofrontal cortex (all seed-based d mapping z value >
20 y excitotoxic lesions of either the anterior orbitofrontal cortex (antOFC) or ventrolateral prefronta
22 , FDR-corrected p (p(FDR))=<0.001-0.002) and orbitofrontal cortex (beta=0.51-0.57, t=3.53-4.30, p(FDR
24 ionally distinct learning signals in lateral orbitofrontal cortex (lOFC) and the dopaminergic ventral
25 t work in macaques has suggested the lateral orbitofrontal cortex (lOFC) is relatively more concerned
26 sed if pharmacologic inactivation of lateral orbitofrontal cortex (lOFC) or DBS of the ventral striat
28 entromedial prefrontal cortex (vmPFC)/medial orbitofrontal cortex (mOFC) organize abstract and discre
29 overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three
30 critical for odor memory and perception- and orbitofrontal cortex (OFC) - a region involved in revers
32 pERK expression in medial prefrontal (mPFC), orbitofrontal cortex (OFC) and areas in striatum and amy
34 bregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal co
36 multaneously decrease neural activity in the orbitofrontal cortex (OFC) and increase activity in NAC
37 we used this model to study the role of the orbitofrontal cortex (OFC) and its afferent projections
38 ned the activation patterns of cue-activated orbitofrontal cortex (OFC) and nucleus accumbens (NAc) s
39 ed consequences, a process that involves the orbitofrontal cortex (OFC) and potentially, the plastici
40 omic and functional connectivity between the orbitofrontal cortex (OFC) and the amygdala in mice.
41 STATEMENT Dysfunctional interactions between orbitofrontal cortex (OFC) and the amygdala underlie sev
42 in piriform and in two downstream areas, the orbitofrontal cortex (OFC) and the medial prefrontal cor
43 IFICANCE STATEMENT Considering that both the orbitofrontal cortex (OFC) and the opioid system regulat
46 the function of several anatomically defined orbitofrontal cortex (OFC) circuits during adaptive, fle
49 lations of neurons and HGA recorded from the orbitofrontal cortex (OFC) encode similar information, a
50 is, when agents make choices, neurons in the orbitofrontal cortex (OFC) encode the subjective value o
51 ing economic decisions, offer value cells in orbitofrontal cortex (OFC) encode the values of offered
55 nsequences of choices.SIGNIFICANCE STATEMENT Orbitofrontal cortex (OFC) has been implicated in repres
59 ructure connecting these two regions via the orbitofrontal cortex (OFC) in 38 healthy human participa
60 MD from its other main cortical target, the orbitofrontal cortex (OFC) in a task assessing outcome d
61 sampled, we found greatest pathology in left orbitofrontal cortex (OFC) in FTLD-TDP, which was greate
62 utions of the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) in rats to learning under exp
65 nt cocaine-induced strengthening of upstream orbitofrontal cortex (OFC) inputs to the dorsomedial str
67 ion later in life.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is a subregion of the frontal
68 nd retrieving associations, while the medial orbitofrontal cortex (OFC) is an important region for re
69 directed behavior.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is critical for goal-directed
72 NCE STATEMENT It is widely accepted that the orbitofrontal cortex (OFC) is important for decision-mak
73 Here we show that neural activity in rat orbitofrontal cortex (OFC) is instead highly structured:
80 and that low-frequency theta activity in the orbitofrontal cortex (OFC) negatively correlates with ph
82 nd recorded from dorsomedial PFC (dmPFC) and orbitofrontal cortex (OFC) neurons while they were freel
83 the activity of neurons in the amygdala and orbitofrontal cortex (OFC) of monkeys during a Pavlovian
84 at heavy alcohol use activates mTORC1 in the orbitofrontal cortex (OFC) of rodents (Laguesse et al.,
85 quantitative real-time PCR (qRT-PCR) in the orbitofrontal cortex (OFC) of SCZ (N = 29; 20 male and 9
86 monkeys with bilateral lesions of either the orbitofrontal cortex (OFC) or the amygdala could learn a
91 optogenetic manipulations revealed that the orbitofrontal cortex (OFC) supports the BLA in these pro
92 orm of cognitive flexibility mediated by the orbitofrontal cortex (OFC) that we have used previously
93 ed repetitive element loci (RE) in the human orbitofrontal cortex (OFC) using directional RNA sequenc
94 f, as well as other RL related variables, in orbitofrontal cortex (OFC) while three male monkeys perf
95 ions of gray matter volume (GMV) in the left orbitofrontal cortex (OFC) with CpG 5,6 methylation.
98 One hedonic hotspot was found in anterior orbitofrontal cortex (OFC), and another was found in pos
99 er cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingu
100 CANCE STATEMENT Economic choices rely on the orbitofrontal cortex (OFC), but other brain regions may
101 nes of evidence link economic choices to the orbitofrontal cortex (OFC), but other brain regions may
102 ces between goods are thought to rely on the orbitofrontal cortex (OFC), but the decision mechanisms
106 vity in both medial and lateral parts of the orbitofrontal cortex (OFC), only the lateral OFC represe
109 in 3 regions linked to decision-making, the orbitofrontal cortex (OFC), ventral striatum (VS), and d
110 c signals in the nucleus accumbens (NAc) and orbitofrontal cortex (OFC), while freely moving rats per
111 representation of decision variables in the orbitofrontal cortex (OFC)-an area implicated in economi
127 ng value-guided learning, whereas the medial orbitofrontal cortex (often referred to as ventromedial
128 hree other frontal cortical regions: lateral orbitofrontal cortex (orbital part of area 12 [12o]), ci
129 d with cortical atrophy in the right lateral orbitofrontal cortex (p(adj) = 0.03) and right posterior
130 ulated the food-related signal in the medial orbitofrontal cortex (P=0.01) and nucleus accumbens (P=0
131 irectional dialogue of the primate posterior orbitofrontal cortex (pOFC) with the amygdala is essenti
132 significantly correlated with TSPO VT in the orbitofrontal cortex (uncorrected Pearson correlation r
133 havioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive con
134 the ventromedial prefrontal cortex / medial orbitofrontal cortex (vmPFC/mOFC) and nineteen age- and
135 n brain regions involved in decision-making (orbitofrontal cortex [OFC]) and action selection (striat
136 We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over
138 associated with nucleus accumbens and medial orbitofrontal cortex activity, whereas distress was pref
139 ted hyperconnectivity in a network involving orbitofrontal cortex along with a less resilient global
140 fiber bundle connecting the amygdala to the orbitofrontal cortex and a key component of the medial t
141 taste, olfactory, and flavor stimuli in the orbitofrontal cortex and a region to which it projects,
143 ve control and emotion regulation (e.g., the orbitofrontal cortex and anterior insula), expressed as
144 a positive functional connectivity with the orbitofrontal cortex and insula to implicit happiness, b
145 ation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequ
146 and functional abnormalities in left lateral orbitofrontal cortex and right supplementary motor area,
147 ine, enhancement of connectivity between the orbitofrontal cortex and subcortical regions correlated
148 he anterior and middle cingulate cortex, the orbitofrontal cortex and the medial and ventromedial sup
149 TEMENT The lateral and medial regions of the orbitofrontal cortex are cytoarchitectonically distinct
150 anterior cingulate cortex, insula and medial orbitofrontal cortex as well as amygdala volume in fear
151 functional connectivity involved the medial orbitofrontal cortex Brodmann area 13, which is implicat
152 t the functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 with these thre
153 vo dopamine tone in the ventral striatum and orbitofrontal cortex correlate with model-based, but not
154 teral prefrontal cortex and amygdala-lateral orbitofrontal cortex coupling were shown in male BPD pat
155 d, across an unbiased sample of neurons, the orbitofrontal cortex differentiated distractor condition
156 lity of task representations recorded in the orbitofrontal cortex during decision-making, which were
159 FC to loss and greater right pars orbitalis-orbitofrontal cortex FC to reward may be trait-level neu
160 s OCP: p = 0.001, OBP versus OHP: p = 0.038) orbitofrontal cortex FC to reward versus OCP and OHP, re
161 e performed with (123)I-PIP using postmortem orbitofrontal cortex from cognitively normal and AD huma
162 hometry analyses demonstrated greater medial orbitofrontal cortex gray matter intensity in controls t
163 g of the functions of different parts of the orbitofrontal cortex in emotion helps to provide new ins
164 Our results not only reveal a role for the orbitofrontal cortex in learning but also have implicati
165 ctivation in the anterior insula and lateral orbitofrontal cortex in response to a high-fat/high-suga
166 ptogenetic stimulation revealed that lateral orbitofrontal cortex input to SPNs was reduced in KOs (~
167 task as well as from other sources, that the orbitofrontal cortex is a critical node in the neural ci
170 new optogenetic lesion study shows that the orbitofrontal cortex is essential for integrating inform
171 credit assignment, whereas damage to medial orbitofrontal cortex meant that patients were more likel
172 monitor and manipulate the activity of many orbitofrontal cortex neurons at the single-cell level in
174 ession was also significantly reduced in the orbitofrontal cortex of high cocaine-escalating rats.
176 extracellular recordings in the striatum and orbitofrontal cortex of mice that learned the temporal r
177 d large-scale recordings in the striatum and orbitofrontal cortex of mice trained on a stimulus-rewar
179 , with a blunted response to the drug in the orbitofrontal cortex of PWSICdel mice, but no difference
180 once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immedi
181 Here we show that basolateral amygdala to orbitofrontal cortex projections are required for expect
182 tes of task representations that suggest the orbitofrontal cortex represents 'task states', deploying
183 ect and dorsal lateral prefrontal and medial orbitofrontal cortex responses to emotionally-conflictin
186 potent cellular-level subnetworks within the orbitofrontal cortex that can be precisely engaged to bi
187 e identified distinct populations within the orbitofrontal cortex that selectively responded to eithe
189 the MDmc may convey signals forwarded to the orbitofrontal cortex to monitor and update the status of
190 facilitate adaptive behavior by enabling the orbitofrontal cortex to use environmental stimuli to gen
195 e, but the striatal network outperformed the orbitofrontal cortex, a finding replicated both in simul
196 erience-specific neuronal populations in the orbitofrontal cortex, a major reward-processing hub that
197 , participants had increased activity in the orbitofrontal cortex, a region often implicated in valua
198 gaging connectivity between rACC and lateral orbitofrontal cortex, a region reflecting outcome value
201 lower was their D2-type BPND in the lateral orbitofrontal cortex, an important region in value-based
202 VC DBS connected primarily to the medial orbitofrontal cortex, and amSTN DBS to the lateral orbit
205 that connectivity to the prefrontal cortex, orbitofrontal cortex, and cingulate cortex was positivel
206 ous, including the medial prefrontal cortex, orbitofrontal cortex, and different locations within the
207 bic regions such as the amygdala, insula and orbitofrontal cortex, and functional abnormalities in ov
208 attern separation between odor categories in orbitofrontal cortex, and impeded within-category genera
210 0.25) in the left superior temporal cortex, orbitofrontal cortex, and left superior frontal cortex.
212 nit activity were acutely implanted into the orbitofrontal cortex, anterior cingulate cortex, dorsal
213 hypometabolism in the medial occipital lobe, orbitofrontal cortex, anterior temporal lobe, and caudat
214 ting that cortical mechanisms, especially in orbitofrontal cortex, are likely involved in attentional
215 a neural state model encoded in human medial orbitofrontal cortex, as measured using multivariate fun
216 e ensemble in the nucleus accumbens, but not orbitofrontal cortex, compared with their surrounding ne
217 of a downstream premotor area (ALM), but not orbitofrontal cortex, confined to the epoch preceding th
218 frontal cortex, and amSTN DBS to the lateral orbitofrontal cortex, dorsal anterior cingulate cortex,
219 eus accumbens, medial prefrontal cortex, and orbitofrontal cortex, during information expectation ver
220 subcortical networks, notably affecting the orbitofrontal cortex, frontal gyrus, amygdala, hippocamp
221 and emotional processing (thalamus, insula, orbitofrontal cortex, hippocampus, and anterior cingulat
222 cant reductions in gray matter volume in the orbitofrontal cortex, hippocampus, and cerebellum; white
223 lateral dorsolateral prefrontal cortex, left orbitofrontal cortex, inferior frontal gyrus, right supe
224 right-sided network of regions involving the orbitofrontal cortex, inferomedial temporal lobe and cer
226 hanges in GMD in some regions, including the orbitofrontal cortex, insula, and amygdala, were persist
227 vealed hypoactivation in additional hedonic (orbitofrontal cortex, insula, globus pallidus, putamen,
228 rey matter volume in the anterior cingulate, orbitofrontal cortex, left dorsolateral prefrontal corte
230 emonstrate that aspiration lesion of central orbitofrontal cortex, of the type known to affect discri
231 ated with longer sleep duration included the orbitofrontal cortex, prefrontal and temporal cortex, pr
232 tern of functional connectivity to the right orbitofrontal cortex, right inferior temporal gyrus, and
233 of the stimulation site with right and left orbitofrontal cortex, right ventromedial prefrontal cort
234 the activity of the cortex, particularly the orbitofrontal cortex, severely impairs higher order cogn
235 solateral prefrontal cortex, and the lateral orbitofrontal cortex, significantly moderated the effect
236 ntravenous) administration in brain regions (orbitofrontal cortex, striatum, brainstem, and thalamus)
237 TSPO VT was measured in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
238 r TSPO VT is elevated in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
239 , in a selective subset of regions including orbitofrontal cortex, the phenomenon was best explained
240 However, in a few other regions, including orbitofrontal cortex, the phenomenon was best explained
242 neurons in central and basolateral amygdala, orbitofrontal cortex, ventral and dorsal medial prefront
243 dies, MAM (vs. SHAM) rats displayed abnormal orbitofrontal cortex-mediated decision-making processes,
245 of the most influential accounts of central orbitofrontal cortex-that it mediates behavioral flexibi
266 y matter changes were prominent in posterior orbitofrontal cortex/anterior insula but were also found
267 econd analysis, neural activity in posterior orbitofrontal cortex/anterior insula was measured at res
269 significant asymmetry in both olfactory and orbitofrontal cortical odor-evoked activity, which is ex
270 mposite score was negatively associated with orbitofrontal cortical thickness (p < 0.05, corrected).
271 in the cerebellum, pons, left amygdala, and orbitofrontal cortices (cluster level, family-wise error
273 reduced volume in the ventral prefrontal and orbitofrontal cortices among youth reporting STBs, and t
274 atients with bvFTD, with the addition of the orbitofrontal cortices and nucleus accumbens in patients
275 he development of dorsal frontal and lateral orbitofrontal cortices as well as the effects of family
276 onstrate a critical role of the piriform and orbitofrontal cortices in relapse to opioid seeking afte
277 s on top-down control from the prelimbic and orbitofrontal cortices over striatal activity through di
278 seline MOR availability in the cingulate and orbitofrontal cortices was associated with the rate of s
279 tural connectivity between supratemporal and orbitofrontal cortices, and between orbitofrontal and nu
284 ion in the dorsomedial prefrontal cortex and orbitofrontal gyrus, and higher relative HDAC expression
285 the right hippocampus/parahippocampus, right orbitofrontal gyrus, right inferior temporal gyrus (ITG)
287 ctivation impacts task performance, but only orbitofrontal inactivation reverts mice from an inferenc
288 licated in emotion regulation, including the orbitofrontal, lateral temporal, and medial temporal cor
289 trate that a connectivity-defined cell type, orbitofrontal neurons projecting to the striatum, carrie
292 onses of neurons in two core reward regions, orbitofrontal (OFC) and ventromedial prefrontal cortex (
293 es on the principal pyramidal neurons of the orbitofrontal prefrontal cortex (oPFC) were also imaged
294 as such as the thalamus, globus pallidus and orbitofrontal regions of the right hemisphere (with the
299 ivisions of the prefrontal cortex, including orbitofrontal, ventrolateral, dorsolateral, and ventrome
300 We found functional connectivity changes in orbitofrontal, ventromedial prefrontal, inferotemporal,