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1 s; decreased brain activity in right lateral orbitofrontal cortex).
2 d by the evolution of a neural schema in the orbitofrontal cortex.
3 r temporal sulcus, the posterior insula, and orbitofrontal cortex.
4 ic symptoms with the local efficiency of the orbitofrontal cortex.
5 rtex/superior frontal gyrus, and left medial orbitofrontal cortex.
6 a in the mPFC and hippocampus but not in the orbitofrontal cortex.
7 , the striatum consistently outperformed the orbitofrontal cortex.
8 pairments can be linked to lateral or medial orbitofrontal cortex.
9 egration in the superior temporal sulcus and orbitofrontal cortex.
10 n the right superior temporal cortex and the orbitofrontal cortex.
11 t project to the MDmc, which projects to the orbitofrontal cortex.
12 ng in addiction, here showing a role for the orbitofrontal cortex.
13 necting ventromedial subthalamic nucleus and orbitofrontal cortex.
14 ations were seen in the ventral striatum and orbitofrontal cortex.
15 s indicates that this behavior relies on the orbitofrontal cortex.
16 frontal cortex and decreased activity in the orbitofrontal cortex.
17 efrontal cortex, temporal cortex, and medial orbitofrontal cortex.
18 dorsomedial frontal, anterior cingulate, and orbitofrontal cortex.
19 ty in reversal tasks lies beyond the central orbitofrontal cortex.
20 cortex, and negatively in the precuneus and orbitofrontal cortex.
21 ubstance, included the insula and the medial orbitofrontal cortex.
22 ampus/parahippocampus, striatum, insula, and orbitofrontal cortex.
23 l, motor, and prefrontal (i.e., ventromedial orbitofrontal) cortex.
24 e, but the striatal network outperformed the orbitofrontal cortex, a finding replicated both in simul
25 erience-specific neuronal populations in the orbitofrontal cortex, a major reward-processing hub that
26 , participants had increased activity in the orbitofrontal cortex, a region often implicated in valua
27 gaging connectivity between rACC and lateral orbitofrontal cortex, a region reflecting outcome value
29 We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over
31 study provides evidence for the key role of orbitofrontal cortex activity in choice behavior and sho
32 associated with nucleus accumbens and medial orbitofrontal cortex activity, whereas distress was pref
33 l operculum, supramarginal gyrus, and medial orbitofrontal cortex (all seed-based d mapping z value >
34 ted hyperconnectivity in a network involving orbitofrontal cortex along with a less resilient global
37 the DMS CINs also depended completely on the orbitofrontal cortex, an area that has been proposed to
38 encoded in patterns of brain activity in the orbitofrontal cortex, an area that has been separately i
39 lower was their D2-type BPND in the lateral orbitofrontal cortex, an important region in value-based
40 fiber bundle connecting the amygdala to the orbitofrontal cortex and a key component of the medial t
41 taste, olfactory, and flavor stimuli in the orbitofrontal cortex and a region to which it projects,
43 ve control and emotion regulation (e.g., the orbitofrontal cortex and anterior insula), expressed as
46 y, we examined activity of single neurons in orbitofrontal cortex and in ventral and dorsal striatum
47 and RSFC between the midbrain and striatum, orbitofrontal cortex and insula in methamphetamine-depen
48 a positive functional connectivity with the orbitofrontal cortex and insula to implicit happiness, b
49 ation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequ
50 and similar effects were found in the right orbitofrontal cortex and right inferior frontal gyrus.
51 and functional abnormalities in left lateral orbitofrontal cortex and right supplementary motor area,
52 ine, enhancement of connectivity between the orbitofrontal cortex and subcortical regions correlated
53 he anterior and middle cingulate cortex, the orbitofrontal cortex and the medial and ventromedial sup
54 VC DBS connected primarily to the medial orbitofrontal cortex, and amSTN DBS to the lateral orbit
57 that connectivity to the prefrontal cortex, orbitofrontal cortex, and cingulate cortex was positivel
58 ous, including the medial prefrontal cortex, orbitofrontal cortex, and different locations within the
59 bic regions such as the amygdala, insula and orbitofrontal cortex, and functional abnormalities in ov
60 attern separation between odor categories in orbitofrontal cortex, and impeded within-category genera
62 0.25) in the left superior temporal cortex, orbitofrontal cortex, and left superior frontal cortex.
64 ctivity among regions such as vmPFC, lateral orbitofrontal cortex, and parahippocampal gyrus (PHG) du
66 grey matter in the anterior insula, lateral orbitofrontal cortex, anterior cingulate and dorsal stri
67 nit activity were acutely implanted into the orbitofrontal cortex, anterior cingulate cortex, dorsal
68 hypometabolism in the medial occipital lobe, orbitofrontal cortex, anterior temporal lobe, and caudat
69 y matter changes were prominent in posterior orbitofrontal cortex/anterior insula but were also found
70 econd analysis, neural activity in posterior orbitofrontal cortex/anterior insula was measured at res
71 y excitotoxic lesions of either the anterior orbitofrontal cortex (antOFC) or ventrolateral prefronta
72 TEMENT The lateral and medial regions of the orbitofrontal cortex are cytoarchitectonically distinct
73 ting that cortical mechanisms, especially in orbitofrontal cortex, are likely involved in attentional
75 anterior cingulate cortex, insula and medial orbitofrontal cortex as well as amygdala volume in fear
76 a neural state model encoded in human medial orbitofrontal cortex, as measured using multivariate fun
77 , FDR-corrected p (p(FDR))=<0.001-0.002) and orbitofrontal cortex (beta=0.51-0.57, t=3.53-4.30, p(FDR
78 functional connectivity involved the medial orbitofrontal cortex Brodmann area 13, which is implicat
81 eased functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 is related to d
82 t the functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 with these thre
84 e ensemble in the nucleus accumbens, but not orbitofrontal cortex, compared with their surrounding ne
85 of a downstream premotor area (ALM), but not orbitofrontal cortex, confined to the epoch preceding th
86 vo dopamine tone in the ventral striatum and orbitofrontal cortex correlate with model-based, but not
87 teral prefrontal cortex and amygdala-lateral orbitofrontal cortex coupling were shown in male BPD pat
88 ted Fos neurons in central amygdala, but not orbitofrontal cortex, decreased "incubated" nicotine see
89 d, across an unbiased sample of neurons, the orbitofrontal cortex differentiated distractor condition
90 frontal cortex, and amSTN DBS to the lateral orbitofrontal cortex, dorsal anterior cingulate cortex,
91 ce has generally treated prefrontal regions (orbitofrontal cortex, dorsolateral prefrontal cortex, in
92 lity of task representations recorded in the orbitofrontal cortex during decision-making, which were
93 ined the role of parvalbumin interneurons in orbitofrontal cortex during reversal learning by recordi
94 he degree of both affective processes in the orbitofrontal cortex during self-reflection and cognitiv
95 eus accumbens, medial prefrontal cortex, and orbitofrontal cortex, during information expectation ver
98 FC to loss and greater right pars orbitalis-orbitofrontal cortex FC to reward may be trait-level neu
99 s OCP: p = 0.001, OBP versus OHP: p = 0.038) orbitofrontal cortex FC to reward versus OCP and OHP, re
100 ts of the ARs in the caudate nucleus and the orbitofrontal cortex for all of the subjects, and a non-
101 e performed with (123)I-PIP using postmortem orbitofrontal cortex from cognitively normal and AD huma
102 subcortical networks, notably affecting the orbitofrontal cortex, frontal gyrus, amygdala, hippocamp
103 hometry analyses demonstrated greater medial orbitofrontal cortex gray matter intensity in controls t
104 and emotional processing (thalamus, insula, orbitofrontal cortex, hippocampus, and anterior cingulat
105 cant reductions in gray matter volume in the orbitofrontal cortex, hippocampus, and cerebellum; white
106 g of the functions of different parts of the orbitofrontal cortex in emotion helps to provide new ins
107 Our results not only reveal a role for the orbitofrontal cortex in learning but also have implicati
108 ctivation in the anterior insula and lateral orbitofrontal cortex in response to a high-fat/high-suga
109 lateral dorsolateral prefrontal cortex, left orbitofrontal cortex, inferior frontal gyrus, right supe
110 right-sided network of regions involving the orbitofrontal cortex, inferomedial temporal lobe and cer
111 r show that this property of CINs depends on orbitofrontal cortex input and is correlated with choice
112 ptogenetic stimulation revealed that lateral orbitofrontal cortex input to SPNs was reduced in KOs (~
114 hanges in GMD in some regions, including the orbitofrontal cortex, insula, and amygdala, were persist
115 vealed hypoactivation in additional hedonic (orbitofrontal cortex, insula, globus pallidus, putamen,
116 task as well as from other sources, that the orbitofrontal cortex is a critical node in the neural ci
119 new optogenetic lesion study shows that the orbitofrontal cortex is essential for integrating inform
120 rey matter volume in the anterior cingulate, orbitofrontal cortex, left dorsolateral prefrontal corte
122 ionally distinct learning signals in lateral orbitofrontal cortex (lOFC) and the dopaminergic ventral
123 t work in macaques has suggested the lateral orbitofrontal cortex (lOFC) is relatively more concerned
124 sed if pharmacologic inactivation of lateral orbitofrontal cortex (lOFC) or DBS of the ventral striat
126 credit assignment, whereas damage to medial orbitofrontal cortex meant that patients were more likel
128 dies, MAM (vs. SHAM) rats displayed abnormal orbitofrontal cortex-mediated decision-making processes,
129 reward values are represented in the medial orbitofrontal cortex (mOFC) at the time of choice [7-9].
130 s or chemogenetic inactivation of the medial orbitofrontal cortex (mOFC) in rats induces failures in
131 entromedial prefrontal cortex (vmPFC)/medial orbitofrontal cortex (mOFC) organize abstract and discre
132 overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three
133 a given reward, or "reinforcer." The medial orbitofrontal cortex (mOFC), a subregion of the ventrome
134 us accumbens, amygdala, anterior insula, and orbitofrontal cortex (n = 18 had analyzable fMRI data).
135 monitor and manipulate the activity of many orbitofrontal cortex neurons at the single-cell level in
138 ession was also significantly reduced in the orbitofrontal cortex of high cocaine-escalating rats.
140 extracellular recordings in the striatum and orbitofrontal cortex of mice that learned the temporal r
141 d large-scale recordings in the striatum and orbitofrontal cortex of mice trained on a stimulus-rewar
143 , with a blunted response to the drug in the orbitofrontal cortex of PWSICdel mice, but no difference
144 processing of affect; nucleus accumbens and orbitofrontal cortex of the reward circuit; anterior ins
145 emonstrate that aspiration lesion of central orbitofrontal cortex, of the type known to affect discri
146 critical for odor memory and perception- and orbitofrontal cortex (OFC) - a region involved in revers
148 pERK expression in medial prefrontal (mPFC), orbitofrontal cortex (OFC) and areas in striatum and amy
149 ically between drug-activated neurons in the orbitofrontal cortex (OFC) and coactive DS neurons.
150 bregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal co
152 multaneously decrease neural activity in the orbitofrontal cortex (OFC) and increase activity in NAC
153 we used this model to study the role of the orbitofrontal cortex (OFC) and its afferent projections
154 ned the activation patterns of cue-activated orbitofrontal cortex (OFC) and nucleus accumbens (NAc) s
155 ed consequences, a process that involves the orbitofrontal cortex (OFC) and potentially, the plastici
156 omic and functional connectivity between the orbitofrontal cortex (OFC) and the amygdala in mice.
157 STATEMENT Dysfunctional interactions between orbitofrontal cortex (OFC) and the amygdala underlie sev
158 in piriform and in two downstream areas, the orbitofrontal cortex (OFC) and the medial prefrontal cor
159 IFICANCE STATEMENT Considering that both the orbitofrontal cortex (OFC) and the opioid system regulat
162 the function of several anatomically defined orbitofrontal cortex (OFC) circuits during adaptive, fle
165 lations of neurons and HGA recorded from the orbitofrontal cortex (OFC) encode similar information, a
166 is, when agents make choices, neurons in the orbitofrontal cortex (OFC) encode the subjective value o
167 ing economic decisions, offer value cells in orbitofrontal cortex (OFC) encode the values of offered
172 nsequences of choices.SIGNIFICANCE STATEMENT Orbitofrontal cortex (OFC) has been implicated in repres
178 ructure connecting these two regions via the orbitofrontal cortex (OFC) in 38 healthy human participa
179 MD from its other main cortical target, the orbitofrontal cortex (OFC) in a task assessing outcome d
180 tly recorded local field potentials from the OrbitoFrontal Cortex (OFC) in five human subjects perfor
181 sampled, we found greatest pathology in left orbitofrontal cortex (OFC) in FTLD-TDP, which was greate
182 utions of the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) in rats to learning under exp
183 parate lines of research have implicated the orbitofrontal cortex (OFC) in the judgment of social tra
186 nt cocaine-induced strengthening of upstream orbitofrontal cortex (OFC) inputs to the dorsomedial str
188 ion later in life.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is a subregion of the frontal
189 nd retrieving associations, while the medial orbitofrontal cortex (OFC) is an important region for re
190 directed behavior.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is critical for goal-directed
193 NCE STATEMENT It is widely accepted that the orbitofrontal cortex (OFC) is important for decision-mak
194 Here we show that neural activity in rat orbitofrontal cortex (OFC) is instead highly structured:
201 and that low-frequency theta activity in the orbitofrontal cortex (OFC) negatively correlates with ph
203 nd recorded from dorsomedial PFC (dmPFC) and orbitofrontal cortex (OFC) neurons while they were freel
204 the activity of neurons in the amygdala and orbitofrontal cortex (OFC) of monkeys during a Pavlovian
205 at heavy alcohol use activates mTORC1 in the orbitofrontal cortex (OFC) of rodents (Laguesse et al.,
206 quantitative real-time PCR (qRT-PCR) in the orbitofrontal cortex (OFC) of SCZ (N = 29; 20 male and 9
207 monkeys with bilateral lesions of either the orbitofrontal cortex (OFC) or the amygdala could learn a
211 reward contingencies, with the medial versus orbitofrontal cortex (OFC) subregions contributing diffe
213 optogenetic manipulations revealed that the orbitofrontal cortex (OFC) supports the BLA in these pro
214 orm of cognitive flexibility mediated by the orbitofrontal cortex (OFC) that we have used previously
215 from the anterior cingulate cortex (ACC) and orbitofrontal cortex (OFC) to assess network similaritie
216 ed repetitive element loci (RE) in the human orbitofrontal cortex (OFC) using directional RNA sequenc
217 f, as well as other RL related variables, in orbitofrontal cortex (OFC) while three male monkeys perf
218 ions of gray matter volume (GMV) in the left orbitofrontal cortex (OFC) with CpG 5,6 methylation.
221 One hedonic hotspot was found in anterior orbitofrontal cortex (OFC), and another was found in pos
222 and ventral striatum, left insula and middle orbitofrontal cortex (OFC), and right insula projecting
223 er cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingu
224 restingly, we found that inactivation of the orbitofrontal cortex (OFC), but not the dorsal or ventra
225 CANCE STATEMENT Economic choices rely on the orbitofrontal cortex (OFC), but other brain regions may
226 nes of evidence link economic choices to the orbitofrontal cortex (OFC), but other brain regions may
227 ces between goods are thought to rely on the orbitofrontal cortex (OFC), but the decision mechanisms
231 vity in both medial and lateral parts of the orbitofrontal cortex (OFC), only the lateral OFC represe
234 in 3 regions linked to decision-making, the orbitofrontal cortex (OFC), ventral striatum (VS), and d
235 c signals in the nucleus accumbens (NAc) and orbitofrontal cortex (OFC), while freely moving rats per
236 representation of decision variables in the orbitofrontal cortex (OFC)-an area implicated in economi
255 n brain regions involved in decision-making (orbitofrontal cortex [OFC]) and action selection (striat
256 ng value-guided learning, whereas the medial orbitofrontal cortex (often referred to as ventromedial
257 hree other frontal cortical regions: lateral orbitofrontal cortex (orbital part of area 12 [12o]), ci
258 d with cortical atrophy in the right lateral orbitofrontal cortex (p(adj) = 0.03) and right posterior
259 ulated the food-related signal in the medial orbitofrontal cortex (P=0.01) and nucleus accumbens (P=0
261 once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immedi
262 irectional dialogue of the primate posterior orbitofrontal cortex (pOFC) with the amygdala is essenti
263 ated with longer sleep duration included the orbitofrontal cortex, prefrontal and temporal cortex, pr
264 Here we show that basolateral amygdala to orbitofrontal cortex projections are required for expect
265 bjects were presented, neuronal ensembles in orbitofrontal cortex represented distinct value-based sc
266 tes of task representations that suggest the orbitofrontal cortex represents 'task states', deploying
267 ect and dorsal lateral prefrontal and medial orbitofrontal cortex responses to emotionally-conflictin
268 into occipital cortex (left hemisphere) and orbitofrontal cortex (right hemisphere); bilateral precu
269 tern of functional connectivity to the right orbitofrontal cortex, right inferior temporal gyrus, and
270 of the stimulation site with right and left orbitofrontal cortex, right ventromedial prefrontal cort
272 the activity of the cortex, particularly the orbitofrontal cortex, severely impairs higher order cogn
273 solateral prefrontal cortex, and the lateral orbitofrontal cortex, significantly moderated the effect
276 ntravenous) administration in brain regions (orbitofrontal cortex, striatum, brainstem, and thalamus)
278 poral pole), and c) emotion-related regions (orbitofrontal cortex, temporal pole, and amygdala).
279 TSPO VT was measured in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
280 r TSPO VT is elevated in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
281 potent cellular-level subnetworks within the orbitofrontal cortex that can be precisely engaged to bi
282 e identified distinct populations within the orbitofrontal cortex that selectively responded to eithe
283 of the most influential accounts of central orbitofrontal cortex-that it mediates behavioral flexibi
284 , in a selective subset of regions including orbitofrontal cortex, the phenomenon was best explained
285 However, in a few other regions, including orbitofrontal cortex, the phenomenon was best explained
289 the MDmc may convey signals forwarded to the orbitofrontal cortex to monitor and update the status of
290 facilitate adaptive behavior by enabling the orbitofrontal cortex to use environmental stimuli to gen
292 significantly correlated with TSPO VT in the orbitofrontal cortex (uncorrected Pearson correlation r
293 neurons in central and basolateral amygdala, orbitofrontal cortex, ventral and dorsal medial prefront
295 havioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive con
296 the ventromedial prefrontal cortex / medial orbitofrontal cortex (vmPFC/mOFC) and nineteen age- and
299 ogical activity of individual neurons of the orbitofrontal cortex while rats performed a risk task th
300 diagnosis-by-age-by-distance interaction in orbitofrontal cortex with short-range FC being lower in