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1 he abscissa and HFpEF predispositions in the ordinate.
2 e activities of the two ribonucleases are co-ordinated.
4 proteins including the GluN2A subunit, unco-ordinated-5H3 (unc5H3), doublecortin, cyclo-oxygenase, s
5 us bound by phage or a recipient cell) to co-ordinate a late stage morphogenetic or gating reaction t
6 ue: E424, D498, D500 and D502, thought to co-ordinate a magnesium ion, were mutated to alanine; in ad
8 a sophisticated interaction network that co-ordinates a wide range of cellular responses required to
11 in the modulation of myosin-1 dynamics to co-ordinate actin polymerization and membrane reorganizatio
12 ldosterone and insulin, primarily through co-ordinate actions on serum and glucocorticoid regulated k
13 n together, our findings demonstrate that co-ordinate activation and binding of ESE-1, Sp1, and NF-ka
14 wall peptidoglycan sacculus requires the co-ordinated activities of peptidoglycan synthases, hydrola
15 organisms use a variety of mechanisms to co-ordinate activity within a community and accomplish comp
16 -like breathing pattern as defined by the co-ordinated activity of cranial and spinal motor inspirato
17 breathing in mammals is dependent on the co-ordinated activity of cranial and spinal motor outputs t
18 Skeletal integrity is maintained by the co-ordinated activity of osteoblasts, the bone-forming cell
19 signalling within and between tissues to co-ordinate adaptive metabolic responses within the organis
21 scriminated by visual representations early, ordinate and superordinate category levels emerged relat
22 c to specialized actin cables in order to co-ordinate and target the final stages of vesicle secretio
23 ynthetic complexes resulting in spatially co-ordinated and efficient peptidoglycan synthetic activity
25 the two motility systems are functionally co-ordinated and that any system-specific branching of the
26 at domain A and domain B are functionally co-ordinated and topologically arranged in a specific manne
27 of Log relative Intrinsic Activities) as the ordinates and Log(bias) as the abscissae is proposed as
29 nctional syncytium of the hepatic lobule, co-ordinating and amplifying the metabolic responses to mul
33 'clients', and provides insights into the co-ordinated assembly of sequential enzymatic steps in PCNA
34 he results strongly suggest that the loop co-ordinates ATP binding/hydrolysis in trans by the two cat
35 erve as a molecular rheostat to precisely co-ordinate B. subtilis cell size with nutrient availabilit
36 ned that the Aer-2 PAS domain binds penta-co-ordinated b-type haem and that reversible signalling req
37 in V. cholerae biofilm development is to co-ordinate bacterial biofilm accumulation with the presenc
38 them unique to Salmonella, and suggests a co-ordinated bacterial response to conditions that exist at
40 ion process called quorum sensing (QS) to co-ordinate behaviours in response to changes in population
41 Whilst the major enzymes and mechanisms co-ordinating BER are well known, the process of BER in chr
44 ation, indicating that these proteins may co-ordinate both the pilus and flagellum motility systems.
45 acts as a global regulator in C.albicans, co-ordinating both metabolic and morphogenetic responses to
46 ular differentiation of L. pneumophila is co-ordinated by a regulatory circuit that integrates severa
48 In almost all bacteria, cell division is co-ordinated by the essential tubulin homologue FtsZ and re
49 gene expression and chitin synthesis was co-ordinated by the PKC, HOG MAP kinase and Ca2+/calcineuri
50 ported by two zinc ions, each of which is co-ordinated by the tetrahedral arrangement of thiol groups
52 ne metabolism gene expression was tightly co-ordinated by three ArgR/AhrC family regulators, encoded
53 is composed of the active-site zinc ion, co-ordinated by three histidine residues (401, 405 and 411)
55 Site-directed mutagenesis of amino acids co-ordinating Ca2+ drastically decreased the binding of CRP
58 be involved in regulatory mechanisms that co-ordinate cell division and segregation of the chemosenso
61 ogue, is thought to function in spatially co-ordinating cell morphogenesis in conjunction with MreC,
63 on profile from mitochondria designed for co-ordinated cellular assembly to mitochondria highly speci
64 on profile from mitochondria designed for co-ordinated cellular assembly to mitochondria highly speci
65 evealed a fundamental requirement for two co-ordinated cellular processes--cytoskeletal alterations a
67 e for Policy and Practice Information and Co-ordinating Centre evidence library for studies published
68 ique is ideal for simultaneously studying co-ordinate changes in mRNA levels from multiple genes.
69 anipulation of Rab5 expression results in co-ordinate changes to clathrin protein expression levels a
70 related proteins/peptide pairs exhibiting co-ordinated changes expression profile are discovered, whi
71 the accumulation of autoinducers leads to co-ordinated changes in gene expression across the bacteria
74 The electropositive hydrogen face can co-ordinate chloride (K~10(3) ) and to a lesser extent fluo
79 veal that the loop plays a direct role in co-ordinating conformational changes involved in long-range
80 d MtrA form a three-component system that co-ordinates cytokinetic and cell wall homeostatic processe
85 spatiotemporally distinct mechanisms that co-ordinate development of the cranial base with that of th
88 that E. chaffeensis CtrA plays a role in co-ordinating development of the stress resistance for pass
89 ate with central cell cycle regulation to co-ordinate developmental decisions with cell proliferation
90 f the planarian intestine are achieved by co-ordinated differentiation of stem cells and the remodeli
93 ar motor that functions in cell division, co-ordinating division with clearing chromosomal DNA from t
94 here that the drebrin/EB3 pathway, which co-ordinates dynamic microtubule/actin filament interaction
96 cular niche has been described, where the co-ordinated effects of angiogenesis and migration of neuro
97 ensing regulatory system is essential for co-ordinating electron flow and cannot be easily replaced.
100 ce of Pseudomonas aeruginosa involves the co-ordinate expression of a range of factors including type
102 alciparum parasites, and suggest that the co-ordinate expression of PfRh2a, PfRh2b together mediate e
104 that in Streptococcus mutans CSP induced co-ordinated expression of competence and mutacin productio
106 tablishment of neuronal identity requires co-ordinated expression of specific batteries of genes.
111 ural transformation in Vibrio cholerae by co-ordinating expression of the regulators CRP, CytR, HapR
112 ation that is separate from their role in co-ordinating expression of the SPI1 TTSS through hilA.
115 s along the molecular backbone of CNC, we co-ordinated Fe(3)O(4) NPs onto CNC scaffold, which was fur
116 y phase and following starvation, thereby co-ordinating flagella and ribosome assembly and preventing
117 ne expression is extensively regulated to co-ordinate flagellar assembly in both space and time.
118 l and also that the upper and lower limbs co-ordinate for an appropriate whole-body sway response.
120 tructural data, down to the level of atom co-ordinates, for each structure in the Protein Data Bank (
123 versatility likely depends upon carefully co-ordinated gene expression, epigenetic regulation in C. a
124 We describe the molecular machinery that co-ordinates gene transcription at the M-G(1) interval duri
126 otein complex called a cellulosome, which co-ordinates glycoside hydrolase assembly, bacterial adhesi
127 life cycle of Myxococcus xanthus includes co-ordinated group movement and fruiting body formation, an
128 of autolysins and autolysin inhibitors to co-ordinate growth and division with cell wall restructurin
130 benefit to a relatively high degree from co-ordinated implementation of broadly consistent managemen
133 and counter-nick mechanism involving dual co-ordinated incisions that lead to the formation of ligata
134 cells (IECs) from Hdac3(IKO) mice display co-ordinate induction of genes and proteins involved in mit
137 s in a limited number of hepatocytes into co-ordinated intercellular Ca(2+) waves that propagated acr
138 d and asynchronous calcium responses into co-ordinated intercellular calcium waves that spread throug
139 Elective multisystem assessments will be co-ordinated into a 'one stop' admission, bringing the spec
141 ke proteins of actinomycetes are known to co-ordinate iron-sulfur (Fe-S) clusters and are believed to
146 ively, maintains membrane integrity while co-ordinating localized release of MVs with distinct size d
147 lular mechanism to reduce metabolism in a co-ordinated manner when cells become starved for nitrogen.
148 mmune cells that respond to pathogens and co-ordinate many innate and adaptive immune responses.
150 ocess by acting as a molecular timer that co-ordinates membrane targeting with the synthesis of the a
157 dings of the present study illustrate the co-ordinated multi-level adaptations to a mechanical lesion
158 rs to integrate environmental signals and co-ordinate multicellular behaviours that are subsequently
160 at the stages analyzed is not through the co-ordinate non-coding RNA or insulator mechanisms observed
161 r each residue from the three-dimensional co-ordinates of a protein structure to one of eight states.
163 principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms.
164 is known for its highly social behavior, co-ordinated pack predation, and striking vocal repertoire,
165 e cell division regulator GpsB appears to co-ordinate PG synthesis at the septum during division and
166 CA transcriptional regulation and that it co-ordinates phycocyanin and phycocyanobilin biosynthesis i
167 r to have three general functions: (i) to co-ordinate physiological changes involved in developmental
168 cDF-YajC-YidC assembly machinery, thereby co-ordinating pigment delivery, the co-translational insert
169 oplast has recently emerged as pivotal to co-ordinating plant defence responses and as a target of pl
171 at pole-specific control of PopZ function co-ordinates polar development and cell cycle progression b
172 etry of this many constituent subunits is co-ordinated post-transcriptionally remains poorly understo
173 ngs establish a central role for HDAC3 in co-ordinating PPAR-regulated lipid oxidation in the intesti
174 ecretion (T3S) from enteric bacteria is a co-ordinated process with a hierarchy of secreted proteins.
175 us biofilm development is mediated by the co-ordinated production of the biofilm matrix, which can be
176 tory system and implicates this system in co-ordinating production of colonization and virulence dete
178 subtilis unfolds by means of separate but co-ordinated programmes of gene expression within two unequ
181 ic leukaemia protein (PML) nuclear bodies co-ordinate PTEN localization by opposing the action of a p
182 that the 14 sites of mono-phosphorylation co-ordinate RB's interactions and confer functional specifi
183 lls homotypically and heterotypically and co-ordinate reciprocal responses between the different cell
186 controlled by CDK activity, thus allowing co-ordinate regulation of carbohydrate metabolism with cell
187 on of Escherichia coli is responsible for co-ordinate regulation of genes involved in F1845 fimbrial
194 n in S. thermophilus 1275 requires a well-co-ordinated regulation of pathway involved in both EPS ass
196 f LpxTPa , and suggest the existence of a co-ordinated regulatory mechanism that permits adaptation t
197 led at the transpososome is exploited for co-ordinated repair of both target gaps flanking Mu without
201 y regulated dynamic process that requires co-ordinate responses of both epidermal and dermal compartm
204 rtant gaps remain and the mechanisms that co-ordinate responses to external signals remain enigmatic.
205 as graded semiquantitatively on a four-point ordinate scale according to the Outcome Measures in Rheu
207 ene-specific protein-mRNA ratios revealed co-ordinated shifts in control points in gene expression al
208 7 and Cpk1 kinases were found to act as a co-ordinate signalling module, whereas the Ste12alpha trans
212 the entire length of the gut and control co-ordinated smooth muscle contractile activity and other g
213 growth of the tooth and alveolar bone is co-ordinated so that a studied distance always separates th
214 r antagonistic relationships, acting in a co-ordinated spatial and temporal manner on different host
215 , Vibrio cholerae, uses quorum sensing to co-ordinate such complex behaviours as pathogenicity and bi
216 he directions of these force vectors were co-ordinated such that the overall body sway response was a
217 ventional and novel methods for achieving co-ordinate suppression or over-expression of up to three p
218 otein export, but how individual bacteria co-ordinate surface organelle expression to prevent interfe
220 ing and sequencing the swallow cycle, for co-ordinating swallowing with breathing, or for closing the
222 lation of encystation genes, and may help co-ordinate synthesis of cyst wall proteins and polysacchar
224 hospholipid biophysical properties by the co-ordinated synthesis of saturated and unsaturated fatty a
227 ently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain prote
228 platforms for sophisticated devices that co-ordinate the activity of numerous transmembrane molecula
229 tion from the dorsal horn and thereby can co-ordinate the appropriate autonomic response, including a
230 , could be a strategy to non-specifically co-ordinate the behaviour of cells in communities composed
233 Cys-13, to sense oxidative stress and to co-ordinate the expression of genes involved in metabolic s
234 high up in diverse regulatory cascades to co-ordinate the expression of key pathogenicity islands and
235 metabolism indicates that acP may help to co-ordinate the expression of surface structures and cellul
236 lvYC operon of Escherichia coli serves to co-ordinate the expression of this operon with other operon
237 e that IRES system, described herein, can co-ordinate the expression of two important abiotic stress-
239 ation is essential for bacterial cells to co-ordinate the faithful replication and segregation of the
240 on, consistent with the need to spatially co-ordinate the holdfast synthesis machinery with the flage
242 um-located DNA translocase, FtsK, acts to co-ordinate the late steps of Escherichia coli chromosome s
244 of coat assembly, but the mechanisms that co-ordinate the morphogenesis of both structures are largel
245 tion that the core function of LasR is to co-ordinate the production of extracellular factors, althou
246 il to sporulate, exemplifying the need to co-ordinate the timing of SapB production with other develo
247 f the transport systems and by this means co-ordinate the transfer of substrates across the two membr
250 he transmembrane DNA-binding protein ToxR co-ordinates the expression of over 20 genes, including tho
251 Here, we have identified a mechanism that co-ordinates the expression of the Salmonella Typhimurium T
252 transcriptional factor that regulates and co-ordinates the expression of various inflammatory genes.
253 the divisome, a complex of proteins that co-ordinates the invagination of the cytoplasmic membrane,
254 lear antigen (PCNA), a DNA sliding clamp, co-ordinates the processing and joining of Okazaki fragment
255 oxia-inducible transcription factor (HIF) co-ordinates the response of tumours to low oxygen by stimu
261 pGpp facilitates this massive response by co-ordinating the downregulation of genes of the translatio
262 l programs and reveal a novel function in co-ordinating the extent and/or timing of proliferation wit
263 response (APR), which is responsible for co-ordinating the peripheral immunological response to inju
264 ltogether, Hfq plays an important role in co-ordinating the temporal expression of the LEE by control
265 that populations of bacterial cells often co-ordinate their behaviour via diffusible chemical signals
266 ved elaborate communication strategies to co-ordinate their group activities, a process termed quorum
268 ites of several genes, including dnaA, to co-ordinate their transcription with initiation of replicat
269 ftsZ and ssgB, during vegetative growth, co-ordinating their expression during sporulation septation
271 ed to be linked with deprotonation of the co-ordinating thiol groups and folding of the polypeptide.
272 utral pH, approximately four of the eight co-ordinating thiol groups release protons with zinc uptake
274 how the action of its 12 AAA+ domains is co-ordinated to catalyze disaggregation remained unexplaine
275 with YycH and YycI and its activation is co-ordinated to cell division in dividing cells by specific
276 lved in sugar transporting and metabolism co-ordinated to enhance the cell's survival and energy gene
277 rate that upper and lower-limb forces are co-ordinated to produce an appropriate whole-body sway resp
278 t activities are spatially and temporally co-ordinated to promote productive cytoskeletal rearrangeme
279 te hyperbolic space and entropic momentum co-ordinates to describe these spiral structures in Minkows
280 ell to respond to diverse environments by co-ordinating tolC transcription with other appropriate fun
281 d spermatogenesis is dependent on tightly co-ordinated transcriptional and post-transcriptional mecha
282 ntial integral function with relativistic co-ordinate transform, allowing application at radiotherape
284 evels is observed in melanoma models, and co-ordinated upregulation of genes positively regulated by
285 experiments in bioinformatics involve the co-ordinated use of computational tools and information rep
288 tention and saccadic processing therefore co-ordinate well to ensure that relevant locations are atte
293 nstrate that phospholipid biosynthesis is co-ordinated with phosphate utilization via the bHLH protei
295 hia coli, regulation of RNR expression is co-ordinated with the cell cycle, and involves several regu
296 p and firm grip), as well as how they are co-ordinated with the lower limbs to maintain balance.
299 clude that FliI interacts with IQGAP1 and co-ordinates with cdc42 and R-ras to control the formation