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1 otransmitter norepinephrine (NE) via an Oct3 organic cation transporter.
2 1-3, PMAT mainly functions as a polyspecific organic cation transporter.
3 ion, including choline acetyltransferase and organic cation transporters.
4 mbinations predicted the substrates of these organic cation transporters.
5 endothelium is non-vesicular and occurs via organic cation transporters.
6 lap in substrate specificity between the two organic cation transporters.
7 tively transported into cells through BA and organic cation transporters.
8 s a critical role in binding of substrate to organic cation transporters.
9 ing the hypothesis that genetic variation in organic cation transporter 1 (OCT1) affects the response
10 ized that reduced transport of metformin via organic cation transporter 1 (OCT1) could increase metfo
17 olymorphism (SNP) mapping to intron 1 of the organic cation transporter 1 (OCTN1; SLC22A4) gene was a
18 Recently the clinical importance of human organic cation transporters 1 (hOCT1/SLC22A1) and 2 (hOC
19 This compound is an excellent substrate for organic cation transporters 1 and 2, also designated SLC
20 hat mIBG is an excellent substrate for human organic cation transporters 1-3 (hOCT1-3) and the multid
21 could be attributed to the presence of human organic cation transporter-1 (hOCT1) single nucleotide p
22 hat express two point mutations of the human organic cation transporter-1 (hOCT1), R488M and G465R, h
24 .001) and expression of the molecular human organic cation transporter-1 (RR, 1.79; P = .038) as the
25 t deterioration in tubule membrane function (organic cation transporter-1 transport activity) was obs
26 provide evidence for a critical role of the organic cation transporter 2 (OCT2) in satellite glial c
28 on of the Golgi pool of D1DR is dependent on organic cation transporter 2 (OCT2), a dopamine transpor
29 pounds were found to be potent inhibitors of organic cation transporter 2 (OCT2), which contributes t
31 C content, and muscle carnitine transporter [organic cation transporter 2 (OCTN2)] messenger RNA and
33 landscape of solute carriers and identified organic cation transporter 3 (OCT3) (SLC22A3) as a criti
34 maging, we show that Ru265 is transported by organic cation transporter 3 (OCT3) and taken up more ef
42 on to DAT, PQ(+) is also a substrate for the organic cation transporter 3 (Oct3, Slc22a3), which is a
43 onoamine transporter 2 (VMAT2) together with organic cation transporter 3 and monoamine oxidase type
46 glands selectively and highly express OCT3 (organic cation transporter-3), a polyspecific drug trans
47 LDEHYDE 3-PHOSPHATE DEHYDROGENASE (PvGAPC1), ORGANIC CATION TRANSPORTER 4 (PvOCT4), and GLUTATHIONE S
49 thers Fmo1, Cyp2d2, Cyp2d4, Nqo2, as well as organic cation transporters and organic anion transporte
51 to cells, Glc-Pt 1 exploits both glucose and organic cation transporters, both widely overexpressed i
53 ne, Solute Carrier DmSLC22A, a member of the organic cation transporter family, enhances olfactory me
59 ript indicated homology to integral membrane organic cation transporters; hence, we designate this ge
61 noamine transporter (PMAT) is a polyspecific organic cation transporter in the solute carrier 29 (SLC
66 nthetic constructs suggest that a functional organic cation transporter is encoded by the larger open
70 ers, however, no valid biomarker for hepatic organic cation transporter (OCT) 1 has been described to
71 other multidrug transporters, including the organic cation transporter (OCT) 2, is influenced by the
73 catinib resembles the pharmacophore of known organic cation transporter (OCT) inhibitors and reduced
74 l tubule organic anion transporter (OAT) and organic cation transporter (OCT) may be used to evaluate
76 s actively transported into the liver by the organic cation transporter (OCT)1 (encoded by SLC22A1).
79 r, their substrate spectrum and synergy with organic cation transporters OCT1 and OCT2 remain incompl
80 orter is distinct from the previously cloned organic cation transporters (OCT1, OCT2, NKT, NLT, RST,
81 protein-altering variants of the human liver organic cation transporter, OCT1, in Xenopus oocytes.
85 cleotide polymorphisms (SNPs) mapping to the organic cation transporter (OCTN) genes, SLC22A4 and SLC
91 pacity transporters for 5-HT in brain [i.e., organic cation transporters (OCTs) and plasma membrane m
98 re organic cations that rely on polyspecific organic cation transporters (OCTs) to traverse cell memb
99 KT, since the Oats share close homology with organic cation transporters (Octs), it is possible that
106 omologous to previously cloned rat and human organic cation transporters, organic cation transport ki
112 Overall, there are many more polyspecific organic cation transporters than previously estimated.
113 porter (PMAT, SLC29A4) is a new polyspecific organic cation transporter that transports a wide variet
114 emoresistance, impaired uptake through human organic cation transporter type 1 (hOCT1) (gene SLC22A1)
115 Here we demonstrate that expression of the organic cation transporter type 3 (OCT3, SLC22A3), which
118 Oct1/Slc22a1 encodes for a hepatic and renal organic cation transporter which may be important for th
119 ude that PMAT can function as a polyspecific organic cation transporter, which may play a role in org