ライフサイエンスコーパス: organism

1 timalarial drug discovery, against the whole organism.

2 f1-deficiency in the context of a vertebrate organism.

3 o play little or no role in the traits of an organism.

4 fferent moments during the development of an organism.

5 duction of hydrogen peroxide defenses in the organism.

6 eads to each mature cell type in a tissue or organism.

7 for numerous biochemical processes in every organism.

8 ely needed new drug to combat this nefarious organism.

9 chers to later question its value as a model organism.

10 tate synthetic biology efforts in this model organism.

11 on and motor control in a light-weight model organism.

12 ry networks that affect the intricacy of the organism.

13 ly is a vital first step for the study of an organism.

14 formation guaranties reproduction of a whole organism.

15 s has been considered a beneficial commensal organism.

16 ic elements threaten genome integrity in all organisms.

17 in mediating ecological interactions between organisms.

18 . leprae, and 2 of 47 (4.26%) contained both organisms.

19 iological function of metaphosphates in many organisms.

20 development and physiology of multicellular organisms.

21 expressed in live cells, neurons, and small organisms.

22 xperimentally characterize in diverse extant organisms.

23 I (LHCIs) differs substantially in different organisms.

24 tebrates, including both pelagic and benthic organisms.

25 oss-feeding between AOB and nitrite reducing organisms.

26 is known as Spt5 in archaeal and eukaryotic organisms.

27 by functional groups and translated to model organisms.

28 uisition of thermotolerance among coral reef organisms.

29 ve correlations to dietary intake of benthic organisms.

30 e the largest and most complex group of such organisms.

31 o study protein function in cells and living organisms.

32 echnology can likely be used with many model organisms.

33 ns on chromatin dynamics in a range of model organisms.

34 hereby preventing the naming of uncultivated organisms.

35 of enzymatic activity in real time in living organisms.

36 cteria by linking a physical model to actual organisms.

37 ctrum to allow treatment of a wider range of organisms.

38 ng accuracy of the chromosomes of all living organisms.

39 )) is essential to the lifestyles of diverse organisms.

40 essential for the survival of multicellular organisms.

41 ferent from the everyday pressures acting on organisms.

42 rients are inevitable events for most living organisms.

43 fusion and other processes in photosynthetic organisms.

44 tics for the detection of colistin-resistant organisms.

45 namic nano- and microdroplets into cells and organisms.

46 nfection leads to proteotoxic stress in host organisms.

47 could function in FuFA biosynthesis in other organisms.

48 miRNA input from ten frequently investigated organisms.

49 for the development and health of cells and organisms.

50 e high diversity of N-glycosylation in lower organisms.

51 ed in bacteria, yeasts, and other eukaryotic organisms.

52 itro and formed filaments in vivo in several organisms.

53 uctive evolution of peroxisomes in anaerobic organisms.

54 DNA is a fundamental process in all cellular organisms.

55 toliths are spread among most photosynthetic organisms.

56 inase systems and other genetically targeted organisms.

57 l stresses in yeast and in cells from higher organisms.

58 why anthropogenic sensory pollutants impact organisms.

59 and survival (actuarial senescence) in most organisms.

60 nt protein superfamilies found in all living organisms.

61 ntribute to germline gene silencing in other organisms.

62 nds DNA during chromosome replication in all organisms.

63 e flexibility and adaptability to eukaryotic organisms.

64 ferences in species richness among groups of organisms.

65 ven by variation in body size and diet among organisms.

66 served, dynamic period across numerous model organisms(5-8), including mouse(9-18).

67 human and Saccharomyces cerevisiae made this organism a suitable model organism for elucidating molec

68 The results from various archaeal organisms across the archaeal domain of life show surpri

69 Organisms adapt to their environment through coordinated

70 ure (OGT) for every known microbial species, organisms adapted to different temperatures have measura

71 involves the ongoing interaction between an organism and its environment.

72 hat result from the interactions between the organism and its environment.

73 describe the entire life history of a single organism and the effects of toxicant exposure.

74 ces such as fish gills interface between the organism and the external environment and as such are ma

75 des are essential cofactors required by many organisms and are synthesized by a subset of prokaryotes

76 e may fail to identify unusual or fastidious organisms and can misrepresent relative abundance of sam

77 cial and dental development in humans, model organisms and cell lines.

78 and variability of environmental stress that organisms and ecosystems experience, but effects of chan

79 rgical units, involving antibiotic-resistant organisms and enteric outbreaks, as well as those where

80 m various bacterial, archaeal, or eukaryotic organisms and have been evaluated for their ability to c

81 s the role of QS during infection in various organisms and highlight approaches to better understand

82 opment of cell-free platforms from non-model organisms and multiplexed strategies for rapidly assessi

83 ms (TCSs) that are ubiquitous across various organisms and regulate diverse cellular functions.

84 ant metabolite in a number of niches in host organisms and represents an important carbon source for

85 previously characterized exosomes from other organisms and that these EVs contain a defined protein a

86 are present in all major tissues across the organism, and the SCN is their central co-ordinator.

87 nucleolus gene module across very divergent organisms, and in the second, we show how the heterogene

88 hysiological trade-offs in a wide variety of organisms, and our work decodes a hitherto undescribed f

89 in drug targets, gyrA and parC, in all three organisms, and suggest the mutational landscape of those

90 not transfer their transgenic genes to other organisms, and that they cannot survive to propagate in

91 for environmental bacteria compared to model organisms, and the technical difficulties of metagenome

92 actors that are essential for NMD in simpler organisms appear to be dispensable for vertebrate NMD.

93 fungi has shown that P450s profiles in these organisms are affected by their lifestyle.

94 Many organisms are experiencing changing daily light regimes

95 and aberrant mutant phenotypes in laboratory organisms are not included and can be found in other dat

96 Soft tissues of extinct organisms are rarely preserved and, therefore, a proxy f

97 These organisms are thought to produce toxic byproducts that s

98 for identifying low-abundance or contaminant organisms as present.

99 lete, and can be applied to samples from any organism, as long as a sufficient amount of starting mat

100 rging as targets for research, especially in organisms associated with global human health.

101 ent of the high-throughput DNA sequencing of organisms at the population level, an application that i

102 to operate within the context of the current organism being built.

103 esults reveal a general relationship between organism body size and the stochastic-deterministic bala

104 Here we propose that the size of an organism' brain could be an additional, overlooked, driv

105 highlight the current possibilities of this organism, but also identify some of the gaps that could

106 ed between vertebrate and invertebrate model organisms, but currently abnormalities in CDK19 are not

107 Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms

108 Iron is an essential nutrient for most organisms, but its limited availability and inherent tox

109 to be highly toxic to most aquatic nontarget organisms, but little is known about the mechanisms caus

110 was associated with less frequent resistant organisms, but usually did not lead to antibiotic de-esc

111 enomena are also observed, and even the same organism can exhibit different control phenomena dependi

112 The rapid evolution of a trait in a clade of organisms can be explained by the sustained action of na

113 exchange small RNAs with invading eukaryotic organisms can be exploited to provide disease resistance

114 s lead us to move beyond meme-centered or an organism-centered concept of fitness based on free-energ

115 structure of the CAK complex from the model organism Chaetomium thermophilum at 2.6- angstrom resolu

116 ic and physiological studies using the model organism Chlamydomonas reinhardtii, have revealed the fu

117 rated biofilms with P. aeruginosa, and these organisms colocalize in the lung during dual-species inf

118 Schizosaccharomyces pombe, an organism containing numerous gamete (spore)-killing wtf

119 nsing mechanisms of eukaryotic multicellular organisms coordinate hypoxic cellular responses in a spa

120 type of future generations-can influence how organisms cope with environmental change.

121 te-specific labeling of RNAs, semi-synthetic organism creation, and unnatural-amino-acid-containing p

122 When applied to diverse tissue types and organisms, CytoTRACE outperformed previous methods and n

123 We apply GxEMM to a range of human and model organism datasets and find broad evidence of context-spe

124 Studies of model organisms defined intersecting signaling pathways that c

125 nsights from regenerating and metamorphosing organisms, designing robots capable of editing their own

126 Photosynthetic organisms developed nonphotochemical quenching (NPQ), a

127 rograms that are coordinated with tissue and organism development.

128 In multicellular organisms different types of tissues have distinct gene

129 ny of the key adaptations that arise in this organism during infection are centered on core metabolis

130 icro- and/or nanoplastics (MP/NP) on diverse organisms (e.g., birds, fish, and mammals).

131 at, before the emergence of silica-secreting organisms, elevated SiO(2)(aq) concentrations in Precamb

132 Many photosynthetic organisms employ a CO(2) concentrating mechanism (CCM) t

133 h organisms harbor mobile AR genes and which organisms engage in HGT.

134 ts should include a description of the host, organism, environmental source of the specimen, spatial-

135 changes in the abundance and distribution of organisms, especially plants, can alter resource landsca

136 mic evolution, and those are best suited for organisms evolving under weak selective pressures, such

137 Many organisms exchange small RNAs (sRNAs) during their inter

138 f the trade-off between stress tolerance and organism fitness is scarce and blurred by the interactio

139 revisiae made this organism a suitable model organism for elucidating molecular mechanisms of copper

140 gate symbiont and dependent on a second host organism for growth and cellular replication.

141 invasive virus that has been used as a model organism for studying common properties of all herpesvir

142 ster has historically been a workhorse model organism for studying developmental biology.

143 Pneumocystis antibody opsonizes Pneumocystis organisms for greater phagocytosis and may also mask ant

144 sis of nat-siRNAs in larger and more complex organisms for the first time.

145 ia constitute a remarkable example of living organisms for which motion can be easily controlled remo

146 (4) (+)) transporters has been identified in organisms from all domains of life.

147 The genomes of organisms from all three domains of life harbor endogeno

148 , had nine values among our compartments and organisms >1.0 (range of 0.57 to 2.33); it is possible t

149 This process is critical in helping organisms guide attention toward the most salient and no

150 In contrast, the closely related organism Halorhodospira halochloris is limited to using

151 spread of AR, it is paramount to know which organisms harbor mobile AR genes and which organisms eng

152 while a normal developmental process in some organisms, has the potential to cause extensive loss of

153 ence is that normal cells in a multicellular organism have evolved in competition between high-level

154 me paradigms and metabolic networks de novo, organisms have evolved strategies to neutralize the impa

155 r technologies applicable to nonconventional organisms have had in these discoveries, and outline new

156 ary determinants of gene regulation in these organisms; however, few have defined roles in specific s

157 ) is increasingly used for monitoring marine organisms; however, offshore sampling and time lag from

158 mens, respectively, and were the most common organisms identified.

159 itself an ectobiont of another single-celled organism.IMPORTANCE Here, we present evidence of the fir

160 Caenorhabditis elegans is a valuable model organism in biomedical research that has led to major di

161 a detailed understanding of the role of this organism in cancer progression is limited, in part due t

162 adus morhua) has recently emerged as a model organism in environmental toxicology studies, and increa

163 ctive DNA sequencing of coexisting microbial organisms in an environmental sample or a host.

164 lidase producer and one of the most abundant organisms in BV.

165 al species lend themselves to becoming model organisms in multiple biological disciplines: one of the

166 in infection rates with antibiotic-resistant organisms in the 2 to 6 years post-implementation.

167 f climate change for the metabolism of these organisms in the natural environment.

168 a of the phylum Thaumarchaeota are important organisms in the nitrogen cycle, but the mechanisms driv

169 that are often collected in humans and model organisms including body images and whole-genome gene ex

170 ance of all the identified biclusters in any organism, including those without substantial functional

171 was extensively studied in photoautotrophic organisms, including plants, algae, and cyanobacteria, w

172 ation and infection with multidrug-resistant organisms, including vancomycin-resistant Enterococcus f

173 amin, we postulate that they acquire it from organisms inhabiting a shared ecological niche-for examp

174 The metabolic state of an organism instructs gene expression modalities, leading t

175 trated a capability for detecting whether an organism involved in such an event has been genetically

176 eDNA shed by organisms is captured in grab samples, concentrated by f

177 identify and characterize new cancer-related organisms is ongoing.

178 Converging theories suggest that organisms learn and exploit probabilistic models of thei

179 Characterization of circadian systems at the organism level-a top-down approach-has led to definition

180 cidating developmental lineages at the whole organism level.

181 n mutant animals, allowing us to interrogate organism-level phenotypes.

182 elle, single-cell, tissue section, and whole organism levels.

183 ganisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms

184 ganisms like bacteria and yeast and immobile organisms like plants that constantly need to adapt to c

185 f those neurons have been studied in diverse organisms, links between the proposed algorithms and ani

186 Yeast and other organisms live longer when they lack specific ribosomal

187 Here, we addressed whether organisms living in naturally more radioactive habitats

188 These data raise concern that nontarget organisms may be exposed to potentially toxic levels of

189 With data from two model organisms (mice, zebrafish) and five laboratories, we sh

190 survive within this enveloping membrane, the organism must take in nutrients, secrete wastes, export

191 creating novel selective pressures to which organisms must adapt.

192 vely with sufficient flexibility, biological organisms must cognize beyond immediate reaction to a ph

193 reater daily temperature variation and moves organisms nearer to their thermal limits, while NTW avoi

194 Upon rehydration, organisms need to reactivate metabolism and protein synt

195 molecular biology tools in this fascinating organism, now enabling exciting applications - from spee

196 ly distributed and are among the predominant organisms on the planet.

197 The cognitive abilities of biological organisms only make sense in the context of their enviro

198 y project can be a limiting factor for small organisms or precious samples.

199 both pathways is restricted to chlorophytes, organisms particularly abundant in ocean N(2)O-producing

200 This is predicted to affect wild organisms, particularly because of the central role that

201 Models in disease ecology rarely track organisms past death, yet death from infection can alter

202 and Tet-On/Tet-Off systems can affect whole-organism physiology and function due to off-target effec

203 Invasive organisms pose a global threat and are exceptionally dif

204 nds on identification of clinically relevant organisms present in a sample.

205 e proteins, are well known for their role in organisms' primary and secondary metabolism.

206 Therefore, how organisms protect their future progeny from damage in a

207 edian TTR for major respiratory pathogens by organism ranged from 29.2 to 43.9 h for ID and from 47.9

208 inherited during asymmetric cell division in organisms ranging from yeast to humans.

209 but distantly related to other African clade organisms recovered in the United States or elsewhere.

210 Implementing an extensively drug-resistant organism registry reduced CRE spread, even when only 25%

211 Blood development in multicellular organisms relies on specific tissue microenvironments th

212 nces health span (the length of time that an organism remains healthy) and increases longevity across

213 viduals in closely interacting, group-living organisms remains a challenge.

214 c environments are habitable for terrestrial organisms remains poorly understood.

215 Bayesian models of behavior suggest that organisms represent uncertainty associated with sensory

216 Organisms respond to tissue damage through the upregulat

217 noisy nature of single cells, multicellular organisms robustly generate different cell types from on

218 tals can drive infections, supported by this organism's abilities to persist on dry surfaces and rapi

219 An organism's ability to disperse influences many fundament

220 asively derive the thermodynamic limit to an organism's biomagnification capability (biomagnification

221 nd universal predictive relationships for an organism's body nutrient content have been inconclusive.

222 story plays a crucial role in determining an organism's composition.

223 in which sensory information derived from an organism's experiences is integrated with information ab

224 Phenology is a major component of an organism's fitness.

225 d nutrient requirements-are fine-tuned to an organism's growth and trophic strategy.

226 ntions exist for typhoid, and humans are the organism's only known reservoir.

227 ions of Namapoikia that we use to assess the organism's proposed affinity.

228 This dampened the organism's reaction to subsequent events.

229 hasize the significance of accounting for an organism's sex when studying fungal-bacterial-host dynam

230 to the control of feeding behavior and help organism's survival when they support physiological need

231 t reflect autoantibody aggressiveness to the organism's tissues.

232 tional requirements interact to determine an organism's trophic niche in the context of one of the la

233 FTY720 treatment significantly delayed live organism shedding in the rectal swabs.

234 eruginosa and even the strongly electrogenic organism, Shewanella oneidensis (25 muW/cm(2)).

235 In plants, as in other organisms, sHSPs are upregulated by stress and are propo

236 odification within a given tRNA and with the organism studied.

237 ting the divergence between enzymes based on organism, substrate, and mechanism.

238 hemical stressor posing potential hazards to organisms such as planktonic crustaceans.

239 ules and span the range from primitive model organisms such as Sacchaomyces cerevisiae, which allow f

240 Polyploid organisms such as wheat complicate even the simplest of

241 of regenerating tissues in laboratory model organisms - such as acoel worms, frogs, fish and mice -

242 Model organisms, such as Drosophila, can help to identify and

243 ries of episodic memory, evidence from model organisms suggests that the cornu ammonis 3 (CA3) hippoc

244 a state of suspended development that helps organisms survive extreme environments.

245 ten regarded as a derived adaptation to help organisms survive in variable but predictable environmen

246 While many organisms synthesize robust skeletal composites consisti

247 cells, with cells in different parts of the organism taking on different fates.

248 For the other organism targets, sensitivity and specificity were as fo

249 a-causing parasite Plasmodium falciparum, an organism that has resisted conventional structural-biolo

250 xamples of a virus infecting a single-celled organism that is itself an ectobiont of another single-c

251 conceptual idea of the 'Darwinian Demon': an organism that simultaneously maximizes all fitness trait

252 The goal is to find the two organisms that constitute the mixed sample.

253 e an important contrast to the low-fecundity organisms that have traditionally been applied in evolut

254 As one of the single-celled photosynthetic organisms that inhabit marine, aquatic and terrestrial e

255 ial for the proper function of cells and the organisms that they make up.

256 Parasites are by definition organisms that utilize resources from a host to support

257 ia, fungi, parasites, and archaea, including organisms that were previously undiscovered and those th

258 In eukaryotic photosynthetic organisms, the conversion of solar into chemical energy

259 the appropriate growth and maintenance of an organism; the presence of a tumor can break this equilib

260 In social organisms, this may include selective pressure from the

261 ironments test the limits of life; yet, some organisms thrive in harsh conditions.

262 However, iron overload can damage the organism through a variety of mechanisms, including the

263 eria may not be optimal across all datasets (organisms, tissues or treatments).

264 three enzymes, turning a non-methylotrophic organism to a synthetic methylotroph that grows to a hig

265 as conditions such as starvation require the organism to be awake and active(4), the ability to switc

266 sistent framework to link the genetics of an organism to the reproducible architecture of its connect

267 Understood as a means for organisms to anticipate daily environmental changes, cir

268 ve evolved in competition between high-level organisms to be altruistic, being able to send signals e

269 issolved, hindering the ability of filtering organisms to capture nutrients.

270 g of the responses of ecologically important organisms to changing environmental conditions and emerg

271 ions is inherently limited by the ability of organisms to gain information about one another.

272 ting acclimatization and local adaptation of organisms to global environmental change.

273 sticity in relation to temperature can allow organisms to maintain fitness in response to increasing

274 o their survival is critical for using these organisms to meet current and future demands for food an

275 and Gram-negative Escherichia coli as model organisms to monitor bacterial concentration, decay kine

276 Reinforcement learning allows organisms to predict future outcomes and to update their

277 mpling for the surveillance of enteric fever organisms to provide data on community-level typhoid ris

278 g of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbati

279 to the distribution and functioning of soil organisms to support their conservation and consideratio

280 Organism type, specimen collection time, and hospital te

281 Sexually reproducing organisms use meiosis to generate haploid gametes and fa

282 Multicellular organisms use mitogens to regulate cell proliferation, b

283 the value of targeted approaches to identify organisms utilizing key nutrients and to rationally desi

284 scence, or the production of light by living organisms via chemical reaction, is widespread across Me

285 and/or terrorist/criminal use of pathogenic organisms warrants continued exploration and development

286 When additional organisms were identified by mNGS, there was no change i

287 lly transgenic CRISPR screen in any metazoan organism, which further supported the high efficiency an

288 tor for many biological processes in aerobic organisms, which can synthesize it de novo through a con

289 Oxygen is essential for many organisms who have therefore evolved mechanisms to enabl

290 cose availability, or glucoprivation, elicit organism-wide counter-regulatory responses whose purpose

291 We highlight organism-wide differences in mitochondrial proteins incl

292 How organisms will cope with these changes depends on their

293 Predicting how organisms will respond to future climate change is a cha

294 ) is a 120-kD surface protein complex on the organism with importance in adhesion and immune recognit

295 observe in human cells or T. thermophila, an organism with similar AT-content.

296 observation supports the hypothesis that-in organisms with early X chromosome inactivation-imprinted

297 genome-resolved metagenomics, we identified organisms with hgcA (hgcA+) within the Bacteroidetes and

298 for a clear assessment of how sex ratios of organisms with TSD are affected.

299 itude higher than reported for any non-viral organism, with 93-98% of mutations being RIP-associated.

300 ve been applied to a wide taxonomic range of organisms, yet some of these models have poor fits to em