ライフサイエンスコーパス: origin recognition complex

1 spacing, are bent by EBNA1, and recruit the origin recognition complex.

2 nature and the characteristics of the human origin recognition complex.

3 in multiple, redundant binding sites for the origin recognition complex.

4 t with it being a part of the putative human origin recognition complex.

5 chromatin requires Xorc2, a component of the origin recognition complex.

6 the genome with the highest affinity for the origin recognition complex.

7 ied histone acetyltransferase binding to the origin recognition complex 1 (Hbo1) as a potential Plk1

8 iption start sites are also binding sites of Origin Recognition Complex 1 (ORC1).

9 information regulator 1 protein (Sir1p) and origin recognition complex 1 protein (Orc1p), the larges

10 rocesses including genome replication (ORC1 [origin recognition complex 1], ORC4, ORC6, CDT1, and CDC

11 munoprecipitation assay performed using anti-origin recognition complex 2 (alpha-ORC2) and alpha-LANA

12 cribe the mechanistic roles of two proteins--origin recognition complex 2 (Orc2) and heterochromatin

13 We have identified origin recognition complex 2 (Orc2), a member of the DNA

14 iP replication activity and increases EBNA1, origin recognition complex 2 (ORC2), and minichromosome

15 odomain-containing protein 2 (BRD2), and the origin recognition complex 2 protein (ORC2) and was enri

16 is also exploited by the RIF2 paralog ORC4 (Origin Recognition Complex 4) in Kluyveromyces lactis an

17 In the first phase, the origin recognition complex and Cdc6 prereplication prote

18 mutations in other pre-RC proteins (such as Origin Recognition Complex and Cdc6), but not to mutatio

19 ing minichromosome maintenance proteins, the origin recognition complex and DNA polymerase alpha.

20 ractions between MUM2 and a component of the origin recognition complex and polymerase alpha-primase

21 in to become functionally licensed: ORC (the origin recognition complex) and Cdc6, plus the two compo

22 pull-down assays demonstrate that ORCA-ORC (Origin Recognition Complex) and multiple H3K9 KMTs exist

23 CE3 and Ori-beta, are directly bound by Orc (origin recognition complex), and two-dimensional gel ana

24 Bromodeoxyuridine, origin recognition complex, and the elongation factors m

25 l connection between wild-type Sum1p and the origin recognition complex, and this relationship also c

26 Human cells that lack a subunit in their origin recognition complex are viable, which suggests th

27 The pre-replication complex protein, origin recognition complex-associated (ORCA/LRWD1), pref

28 We find heterochromatin protein 1/origin recognition complex-associated protein (HOAP) to

29 ing by PCNA and CDC45 mutations required the origin recognition complex binding site of the HMR-E sil

30 lication (OBR), which mapped adjacent to the origin recognition complex binding site.

31 The association of origin recognition complex-binding sites with selected p

32 yeast, the eukaryotic initiator protein ORC (origin recognition complex) binds to a bipartite sequenc

33 hat one molecule of the helicase loader ORC (origin recognition complex) can sequentially load two Mc

34 mutations in ORC1, encoding a subunit of the origin recognition complex, cause microcephalic primordi

35 Three additional factors--the origin recognition complex, Cdc6 and Cdt1--are required

36 The origin recognition complex, Cdc6 and the minichromosome

37 ed onto chromatin by the concerted action of origin recognition complex, Cdc6, and Cdt1.

38 A replication, the Orc1 subunit of the human origin recognition complex controls centriole and centro

39 namics require ORCA-dependent differences in origin recognition complex distribution.

40 This atypical ACS binds the origin recognition complex efficiently and is required f

41 SWI/SNF-related complexes co-localizes with origin recognition complexes, GINS complexes, and prolif

42 the six subunits of Saccharomyces cerevisiae origin recognition complex have been reported so far.

43 Histone acetyltransferase binding to origin recognition complex (HBO1) plays a crucial role i

44 and B1 elements, which are known to bind the origin recognition complex; however, the ARS1 A element

45 We report that a highly purified human origin recognition complex (HsORC) has intrinsic DNA-bin

46 n of an initial complex containing the human origin recognition complex (HsORC), HsCdt1, HsCdc6, and

47 Orc5p is a subunit of the origin recognition complex in the budding yeast Saccharo

48 s with two Orc1-like proteins in the unusual origin recognition complex in trypanosomes.

49 ORC2 is a subunit of the origin recognition complex in yeast and has been implica

50 eins we identified is identical to the human origin recognition complex-interacting protein termed HB

51 tional silencing, and ORC is the six-subunit origin recognition complex involved in the initiation of

52 The Xenopus origin recognition complex is essential for chromosomal

53 S1 association of Mcm2p, but not that of the origin recognition complex, is diminished by disruption

54 an evolutionarily conserved component of the origin recognition complex, is essential for deoxyribonu

55 hromatin-bound B-subunit in association with origin recognition complex mediates recruiting Polalpha-

56 o early G1 phase through an interaction with Origin Recognition Complex or another origin-associated

57 The origin recognition complex or ORC is a six-subunit prote

58 is chromatin is perturbed in mutants for the origin recognition complex (ORC) 2 subunit.

59 c cells at the onset of S phase requires the origin recognition complex (ORC) [1].

60 in transcriptional silencing mediated by the origin recognition complex (ORC) and a heterochromatin s

61 eucine enabled Sum1-1p to associate with the origin recognition complex (ORC) and accumulate near ORC

62 the association of the Cdc6 protein with the Origin Recognition Complex (ORC) and appears concomitant

63 y reveal a functional connection between the origin recognition complex (ORC) and Cdc45p but also ext

64 assembly of protein complexes, including the origin recognition complex (ORC) and CDC6 AAA(+) ATPases

65 expected to recruit initiation proteins like origin recognition complex (ORC) and Cdc6 in eukaryotes

66 We show that origin recognition complex (ORC) and Cdc6 recruit multip

67 In contrast, both subunits of origin recognition complex (ORC) and Cdc6, which are req

68 An interaction between the origin recognition complex (ORC) and Cdc6p is the first

69 helicase motor is deposited onto DNA by the origin recognition complex (ORC) and co-loader proteins

70 t1 onto origins bound by the heterohexameric origin recognition complex (ORC) and functions as a repl

71 is determined by the interaction between the origin recognition complex (ORC) and genomic DNA.

72 ts DUE sequence, despite the presence of the origin recognition complex (ORC) and MCM proteins at the

73 Origin Recognition Complex (ORC) and minichromosome main

74 f DNA replication in eukaryotes requires the origin recognition complex (ORC) and other proteins that

75 inhibits MCM loading by phosphorylating the origin recognition complex (ORC) and promotes CMG format

76 were reduced in their ability to recruit the origin recognition complex (ORC) and stimulate OriP repl

77 The origin recognition complex (ORC) and the minichromosome

78 Both, the origin recognition complex (ORC) and the minichromosome

79 alyzed the developmental localization of the origin recognition complex (ORC) and the minichromosome

80 tiate DNA replication and interacts with the origin recognition complex (ORC) and the p34cdc2 CDK.

81 ental stage-specific binding regions for the Origin Recognition Complex (ORC) and the replicative hel

82 Cdc6p and the origin recognition complex (ORC) are essential for assem

83 or is loaded onto replication origins by the origin recognition complex (ORC) as a head-to-head doubl

84 ion assay, we have measured the stability of origin recognition complex (ORC) associated with sperm c

85 itory sequence positioned 3' to the sites of origin recognition complex (ORC) binding and pre-RC asse

86 It begins with the origin recognition complex (ORC) binding DNA sites calle

87 , which flank the silenced loci, includes an origin recognition complex (ORC) binding site (ACS).

88 The origin recognition complex (ORC) binds origins of replic

89 The origin recognition complex (ORC) binds sites from which

90 genome duplication begins when a six-subunit origin recognition complex (ORC) binds to DNA.

91 Although the origin recognition complex (ORC) binds to origins of DNA

92 The Origin Recognition Complex (ORC) binds to sites in chrom

93 The origin recognition complex (ORC) binds to the specific p

94 architecture of the Saccharomyces cerevisiae origin recognition complex (ORC) bound to yeast origins

95 tion that are specifically recognized by the origin recognition complex (ORC) containing multiple ATP

96 The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RN

97 The origin recognition complex (ORC) coordinates bidirection

98 The origin recognition complex (ORC) defines origins of repl

99 In this system, the origin recognition complex (ORC) did not become stoichio

100 The lack of sequence specificity in origin recognition complex (ORC) DNA binding complicates

101 In a Xenopus egg replication system, the origin recognition complex (ORC) does not bind to CpG me

102 0me1-reading BAHCC1 and the H4K20me2-reading Origin Recognition Complex (ORC) ensure genomic loading

103 cle-dependent changes in the affinity of the origin recognition complex (ORC) for chromatin are invol

104 Immunoprecipitation of the origin recognition complex (ORC) from yeast extracts ide

105 The eukaryotic six-subunit origin recognition complex (ORC) governs the initiation

106 The origin recognition complex (ORC) has an important functi

107 A new member of human origin recognition complex (ORC) has been cloned and ide

108 ARS consensus sequence (ACS) that binds the origin recognition complex (ORC) has been experimentally

109 plicative helicase and between one and three origin recognition complex (ORC) homologues involved in

110 first genome-wide analysis of binding of the origin recognition complex (ORC) in a differentiated met

111 tificial locus results in recruitment of the origin recognition complex (ORC) in a manner dependent o

112 The origin recognition complex (ORC) in yeast is a complex o

113 Purified human origin recognition complex (ORC) induces similar topolog

114 The origin recognition complex (ORC) initiates the assembly

115 The origin recognition complex (ORC) is a 6-subunit complex

116 The Origin Recognition Complex (ORC) is a critical component

117 The six-subunit origin recognition complex (ORC) is a DNA replication in

118 The origin recognition complex (ORC) is a DNA replication in

119 The origin recognition complex (ORC) is a six subunit comple

120 Origin recognition complex (ORC) is a six subunit comple

121 The Origin Recognition Complex (ORC) is a six-protein assemb

122 The origin recognition complex (ORC) is a six-subunit, ATP-r

123 The origin recognition complex (ORC) is an essential compone

124 The origin recognition complex (ORC) is an essential DNA rep

125 The Origin Recognition Complex (ORC) is an evolutionarily co

126 The origin recognition complex (ORC) is an initiator protein

127 The six-subunit Origin Recognition Complex (ORC) is believed to be an es

128 The Saccharomyces cerevisiae origin recognition complex (ORC) is bound to origins of

129 The Saccharomyces cerevisiae origin recognition complex (ORC) is composed of six subu

130 The origin recognition complex (ORC) is conserved in all euk

131 le of Saccharomyces cerevisiae, the level of origin recognition complex (ORC) is constant and ORCs ar

132 In eukaryotes, the heterohexameric origin recognition complex (ORC) is essential for coordi

133 The Origin Recognition Complex (ORC) is essential for replic

134 The six-subunit origin recognition complex (ORC) is essential for the in

135 The origin recognition complex (ORC) is involved in formatio

136 e location analysis, we demonstrate that the origin recognition complex (ORC) is localized to specifi

137 The Origin Recognition Complex (ORC) is necessary for orches

138 In eukaryotes, the origin recognition complex (ORC) is required for the ini

139 The origin recognition complex (ORC) is required to initiate

140 visiae, sequence-specific DNA binding by the origin recognition complex (ORC) is responsible for sele

141 The origin recognition complex (ORC) is the DNA replication

142 In eukaryotic cells, the origin recognition complex (ORC) is the initiator protei

143 ORC1, the Origin Recognition Complex (ORC) large subunit, is inher

144 ation for bidirectional DNA replication, the origin recognition complex (ORC) loads two hexameric MCM

145 During origin licensing, the origin recognition complex (ORC) loads two Mcm2-7 helica

146 Drosophila origin recognition complex (ORC) localizes to defined po

147 The origin recognition complex (ORC) marks chromosomal posit

148 The origin recognition complex (ORC) nucleates DNA replicati

149 cetylation of nucleosomes and binding of the origin recognition complex (ORC) occur in a broad domain

150 Mutations in genes encoding the origin recognition complex (ORC) of Saccharomyces cerevi

151 The origin recognition complex (ORC) of Saccharomyces cerevi

152 of a pre-replication complex facilitated by Origin Recognition Complex (ORC) onto the chromatin duri

153 The origin recognition complex (ORC) plays a central role in

154 The origin recognition complex (ORC) plays a central role in

155 The origin recognition complex (ORC) plays a key role during

156 Origin recognition complex (ORC) plays critical roles in

157 c7p kinase activity, or interaction with the origin recognition complex (ORC) postulated to recruit C

158 aintenance (MCM) proteins, together with the origin recognition complex (ORC) proteins and Cdc6, play

159 Origin recognition complex (ORC) proteins serve as a lan

160 Before initiation of DNA replication, origin recognition complex (ORC) proteins, cdc6, and min

161 Budding yeast (Saccharomyces cerevisiae) origin recognition complex (ORC) requires ATP to bind sp

162 The eukaryotic origin recognition complex (ORC) selects the genomic sit

163 The origin recognition complex (ORC) specifies replication o

164 lecule visualization, we show here that S.c. origin recognition complex (ORC) stably binds nucleosome

165 ins by chromatin immunoprecipitation against origin recognition complex (ORC) subunits 2 and 3 showed

166 protein complex of HP1 containing Drosophila origin recognition complex (ORC) subunits in the early D

167 e cyclin-dependent kinases (CDKs) target two origin recognition complex (ORC) subunits, Orc2 and Orc6

168 ure-sensitive mutation in a component of the origin recognition complex (ORC) that also causes a defe

169 role for the Orc1 protein, a subunit of the origin recognition complex (ORC) that is a key component

170 s of binding sites for Abf1p, Rap1p, and the origin recognition complex (ORC) that serve to recruit t

171 emonstrated that EBNA1 recruits the cellular origin recognition complex (ORC) through an RNA-dependen

172 myces cerevisiae requires the binding of the origin recognition complex (ORC) to autonomously replica

173 Binding of the Origin Recognition Complex (ORC) to DNA initiates the AT

174 CM loading is orchestrated by binding of the origin recognition complex (ORC) to DNA, but how ORC coo

175 ion begins with the binding of a six subunit origin recognition complex (ORC) to DNA.

176 ined in part by the binding of a heteromeric origin recognition complex (ORC) to DNA.

177 EBNA1 recruits the origin recognition complex (ORC) to establish a replicat

178 Binding of the Origin Recognition Complex (ORC) to origins of replicati

179 Binding of the Origin Recognition Complex (ORC) to replication origins

180 s solely responsible for in vitro binding of origin recognition complex (ORC) to specific AT-rich sit

181 otein complex (Mcm), topoisomerases, and the origin recognition complex (ORC) using an in vitro assay

182 A new member of the human origin recognition complex (ORC) was cloned and identifi

183 replication initiation and silencing by the origin recognition complex (ORC) was examined.

184 The origin recognition complex (ORC) was initially discovere

185 The six-subunit origin recognition complex (ORC) was originally identifi

186 The origin recognition complex (ORC) was originally identifi

187 The origin recognition complex (ORC) was required for Sum1-1

188 The six-subunit origin recognition complex (ORC), a DNA replication init

189 tic DNA replication initiation relies on the origin recognition complex (ORC), a DNA-binding ATPase t

190 s the silencer through interactions with the origin recognition complex (ORC), a protein complex that

191 In eukaryotes, DNA replication requires the origin recognition complex (ORC), a six-subunit assembly

192 The origin recognition complex (ORC), a six-subunit protein,

193 sequence (ACS) element, presumed to bind the origin recognition complex (ORC), and a broad 3'-flankin

194 meters of transcription, localization of the origin recognition complex (ORC), and histone acetylatio

195 These loci are identified and bound by the origin recognition complex (ORC), and subsequently activ

196 two factors: the sequence preferences of the origin recognition complex (ORC), and the interference o

197 g the role of the prereplication complex and origin recognition complex (ORC), and uncovering regulat

198 he ACS is the binding site for the initiator origin recognition complex (ORC), but the selected seque

199 he prereplicative complex (pre-RC) proteins: origin recognition complex (ORC), CDC-6, and CDT-1.

200 f how the double hexamer is assembled by the origin recognition complex (ORC), CDC6 and CDT1 comes mo

201 The origin recognition complex (ORC), Cdc6 and Cdt1 load Mcm

202 tions of a variety of proteins including the origin recognition complex (ORC), Cdc6 and the Mcm2-7 he

203 Origin recognition complex (ORC), Cdc6, and Cdt1 assembl

204 At each origin, the Origin Recognition Complex (ORC), Cdc6, and Cdt1 co-asse

205 sing of replication origins-during which the origin recognition complex (ORC), CDC6, and CDT1 coopera

206 The loading of Mcm2-7 onto DNA requires the origin recognition complex (ORC), Cdc6, and Cdt1, and de

207 It is recruited to chromatin by the origin recognition complex (ORC), Cdc6, and Cdt1, and it

208 s loaded as a double hexamer onto DNA by the Origin Recognition Complex (ORC), Cdc6, and Cdt1.

209 replicative complexes (pre-RCs) requires the Origin Recognition Complex (ORC), Cdc6, and Cdt1.

210 The sequential binding of the origin recognition complex (ORC), Cdc6, and the minichro

211 lex (pre-RC), and its formation requires the origin recognition complex (ORC), Cdc6, Cdt1, and ATP.

212 ins of replication through the action of the origin recognition complex (ORC), Cdc6, Cdt1, and the Mc

213 ential binding to replication origins of the origin recognition complex (ORC), Cdc6/Cdc18, Cdt1, and

214 The origin recognition complex (ORC), Cdc6p, and minichromos

215 The origin recognition complex (ORC), Cdc6p, and the MCM pro

216 re-RCs) as an inactive double hexamer by the origin recognition complex (ORC), Cdt1 and Cdc6; the hel

217 CM)2-7 recruitment to origins in G1 requires origin recognition complex (ORC), Cdt1, and Cdc6, and ac

218 The origin recognition complex (ORC), composed of six subuni

219 la Orc6 protein, the smallest subunit of the origin recognition complex (ORC), directly binds to sept

220 mechanisms, including phosphorylation of the origin recognition complex (ORC), downregulation of Cdc6

221 The origin recognition complex (ORC), first identified in Sa

222 ctors 1 (TRF1) and 2 (TRF2), subunits of the origin recognition complex (ORC), heterochromatin protei

223 We identify the origin recognition complex (ORC), including LRWD1 as a s

224 ction with Orc1p, the largest subunit of the origin recognition complex (ORC), is critical for Sir1p'

225 we demonstrate that the yeast initiator, the origin recognition complex (ORC), is required to maintai

226 to DNA replication, including a role for the origin recognition complex (ORC), the DNA replication in

227 t sites of DNA replication are marked by the origin recognition complex (ORC), which coordinates Mcm2

228 esemble those generated in vitro by purified origin recognition complex (ORC), which is essential for

229 interaction between origin sequences and the origin recognition complex (ORC), which is highly conser

230 teraction between an origin sequence and the origin recognition complex (ORC), which is highly conser

231 origins of DNA replication are bound by the origin recognition complex (ORC), which scaffolds assemb

232 Origins are bound by the origin recognition complex (ORC), which, with Cdc6 and C

233 eported that a WD repeat-containing protein, origin recognition complex (ORC)-associated (ORCA/LRWD1)

234 ne response element directly adjacent to the origin recognition complex (ORC)-binding site in the II/

235 MCM) double hexamer, its precursors, and the origin recognition complex (ORC)-Cdc6-Cdt1-Mcm2-7 (OCCM)

236 Origin recognition complex (ORC)-dependent loading of th

237 o chromatin states during the cell cycle: an origin recognition complex (ORC)-dependent post-replicat

238 in S phase requires the prior assembly of an origin recognition complex (ORC)-dependent pre-replicati

239 ein-protein interaction between Sir1 and the origin recognition complex (ORC).

240 recognized by the replication initiator, the origin recognition complex (ORC).

241 ogy (BAH) domain of the Orc1p subunit of the origin recognition complex (ORC).

242 eracetylated, coincident with binding of the origin recognition complex (ORC).

243 cyclin Clb5 binds stably and directly to the origin recognition complex (ORC).

244 nism independent of its interaction with the origin recognition complex (ORC).

245 ght to occur at sites bound by a heteromeric origin recognition complex (ORC).

246 that are important for silencing include the origin recognition complex (ORC).

247 es replication factor Orp2, a subunit of the origin recognition complex (ORC).

248 identified as the sixth member of the human origin recognition complex (ORC).

249 aryotes this role is played by a six-protein origin recognition complex (ORC).

250 bind the silencer DNA directly, such as the origin recognition complex (ORC).

251 el protein with homology to a subunit of the origin recognition complex (ORC).

252 ncer, thus arguing for an involvement of the origin recognition complex (ORC).

253 subunit complex of six proteins known as the origin recognition complex (ORC).

254 n factor subunit of Saccharomyces cerevisiae origin recognition complex (ORC).

255 s cerevisiae these sites are occupied by the origin recognition complex (ORC).

256 hich is loaded onto DNA after binding to the Origin Recognition Complex (ORC).

257 proteins: Cdc6, the Mcm2-7 helicase, and the origin recognition complex (ORC).

258 iates from replication origins that bind the Origin Recognition Complex (ORC).

259 proteins and protein complexes, such as the origin recognition complex (ORC).

260 Current models suggest that the origin-recognition complex (ORC) and cell-division cycle

261 During loading, Cdc6, Cdt1, and the origin-recognition complex (ORC) assemble two heterohexa

262 the two pre-replicative complex components (origin recognition complex [ORC] and minichromosome main

263 in components of the prereplicative complex (origin recognition complex [ORC], Cdc6, and minichromoso

264 The function of the 'origin recognition complex' (ORC) in eukaryotic cells is

265 the gene encoding the second subunit of the origin recognition complex, ORC, and MCM3, another membe

266 Here, we report that the human origin recognition complex, ORC, can be detected in asso

267 cerevisiae Orc2 protein is a subunit of the origin recognition complex, ORC, which binds in a sequen

268 In all eukaryotes, the six-subunit origin recognition complex (Orc1-6; ORC) recognizes the

269 gest subunit of the Saccharomyces cerevisiae origin recognition complex (Orc1p) functions in transcri

270 of subunit 5 of the Drosophila melanogaster origin recognition complex (Orc5) and have characterized

271 ition correlate with the activity of hamster origin recognition complexes (ORCs) and the appearance o

272 mammalian chromosomes, the time when hamster origin recognition complexes (ORCs) became functional wa

273 The mechanism by which origin recognition complexes (ORCs) identify replication

274 When the quantity of origin recognition complexes (ORCs) on the chromatin was

275 Eukaryotic initiator proteins form origin recognition complexes (ORCs) that bind to replica

276 Here we report that LANA associates with origin recognition complexes (ORCs) when bound to its 17

277 protein (Orc1p), the largest subunit of the origin recognition complex, plays an important role in t

278 In Drosophila, the largest subunit of the origin recognition complex protein 1 (ORC1) is degraded

279 binding patterns of EBNA1 with those of the origin recognition complex protein ORC2, the chromatin b

280 We report the structure of an archaeal origin recognition complex protein, ORC1, bound to an or

281 ised the interaction of the Aeropyrum pernix origin recognition complex proteins (ORC1 and ORC2) with

282 rget sites that in tissue-culture cells bind origin recognition complex proteins and function as repl

283 enetically interacts and coprecipitates with origin recognition complex proteins Orp1/Orc1 and Orp2/O

284 ats (TR), leading to recruitment of cellular origin recognition complex proteins.

285 , and restriction (including subunits of the origin recognition complex, replication factor C protein

286 n turn, suggest the existence of a mammalian origin recognition complex, similar to that found in yea

287 o OriP in vivo as well as for assembling the origin recognition complex subunit 2 (ORC2) and trimethy

288 Antibody to the origin recognition complex subunit 2 (ORC2) recognizes l

289 encodes the Drosophila homolog of the yeast origin recognition complex subunit 2 (Orc2p), a protein

290 ) polymerase 1 (PARP1), ligase IIIalpha, and origin recognition complex subunit 5.

291 onsisting of the meiotic ATPase Pch2 and the origin recognition complex subunit Orc1.

292 We report that the smallest of Drosophila origin recognition complex subunits, Orc6, was found in

293 n an orderly association, beginning with the origin recognition complex, that culminates in the initi

294 ard B2, adjacent to the binding site for the origin recognition complex, the putative initiator prote

295 consisting of a single binding site for the origin recognition complex, the replication initiator pr

296 Strikingly, DUP protein colocalizes with the origin recognition complex to specific sites in the ovar

297 NA gene amplification, is the T. thermophila origin recognition complex (TtORC).

298 which constitute the core of the replication origin recognition complex, were among the most signific

299 We have immunopurified the Xenopus origin recognition complex with anti-Xorc2 antibodies an

300 atin before licensing can occur: the Xenopus origin recognition complex (XORC) [8] [9] and Xenopus Cd