ライフサイエンスコーパス: originally

1 reate ecological patterns where none existed originally.

2 (Prevencion con Dieta Mediterranea) cohort, originally a randomized trial in which participants foll

3 p(2))-C(sp(2)) and C(sp(3))-C(sp) bonds, was originally achieved for the design of a novel library of

4 elves to exhibit macroscopic chirality in an originally achiral lattice.

5 with CDI and 48599 non-CDI control patients originally admitted from the community were included.

6 eed to continue trial participation on their originally allocated inter-donation intervals (men: 12,

7 including 2',3'-dideoxycytidine (ddC), were originally and are still pursued as anticancer agents.

8 PfATP4 was originally annotated as a Ca(2+) transporter, but recent

9 is context are more nuanced and complex than originally anticipated.

10 Veil-of-ignorance reasoning was originally applied by philosophers and economists to fou

11 uG family is significantly more diverse than originally appreciated, and that MbnH is most closely re

12 019 novel coronavirus (2019-nCoV/SARS-CoV-2) originally arose as part of a major outbreak of respirat

13 ersion 7), 605 of the 3482 taxonomical names originally assigned by the authors of the rbcL sequences

14 ab, and all other patients remained on their originally assigned initial dose up to 48 weeks.

15 re, and reinterpretation of previous studies originally based on the nonhomologous partitioning of ro

16 rted to produce sterols and this anomaly had originally been ascribed to lateral gene transfer (LGT)

17 oves that the structure of this compound had originally been misassigned.

18 '14' and '16' in the top half of the plot we originally both shown as '12'.

19 and surface exposure of hydrophobic epitopes originally buried inside the globule.

20 The temperature parameter as originally calculated for the PBS was not independently

21 ar micro-pattern indicating carbonaceous (or originally carbonaceous) matter.

22 cytosolic DNA-sensing cGAS-STING pathway was originally characterized as a key innate immune mediator

23 Orexins are originally characterized as orexigenic hypothalamic neur

24 BRs were originally characterized for their function in cell elon

25 ere experienced; our studies reveal that the originally characterized material was its carboxylate sa

26 The two major subtypes of RMS, originally characterized on the basis of light microscop

27 It was originally classified as a nephroblastoma cell line but

28 iasetosatanais Larsen and Araujo-Silva, 2014 originally classified within Colletteidae is synonymised

29 While originally coded using MATLAB, compiled packages are als

30 The term "sulfa allergy", originally coined for the sulfonamide antibiotics, has b

31 Ecological release, originally conceived as niche expansion following a redu

32 Originally considered a typical transcription factor rec

33 Although originally defined as a type 2 (T2) immune-mediated cond

34 Since heterochromatin is originally defined as intensely stained chromatin in the

35 ssociated with specific genomic compartments originally defined as Lineage-Specific (LS) regions that

36 Only 4% of the originally deposited PdNPs were lost over 90 days of con

37 and it remains unclear whether these tumors originally derive from BCC or SCC.

38 t that the carbon van der Waals (vdW) radii, originally derived for sp(3) carbons, should not be used

39 sets were well-fit by a computational model originally derived for visual signal combination, but wi

40 Nomacopan, a drug originally derived from tick saliva, has dual functions

41 mater is rich in tissue-resident macrophages originally derived from yolk sac precursors.

42 dataset from that in which the signature was originally derived.

43 Aptian leaf fossil Mesodescolea plicata was originally described as a cycad, but new evidence from c

44 The cyclin-dependent kinase 5 (CDK5), originally described as a neuronal-specific kinase, is a

45 Originally described as a right ventricular disease, ACM

46 In neurons, autophagy was originally described as associated with disease states a

47 ch functional entities as a series of steps, originally described by either TIGRFAMs or Pfam entries.

48 or phenotypes in C9orf72 BAC transgenic mice originally described by Liu et al.

49 oquinone), an air-stable 18-electron complex originally described by Schrauzer in 1962, is a competen

50 Tetherin/BST-2 is a restriction factor, originally described in humans, that blocks the release

51 The GET system was originally described in mammals and yeast but was recent

52 As originally described, cells expressing BirA* fusions wer

53 of internal serine protease inhibitors, was originally designed as a complement factor D inhibitor a

54 s of a large and diverse range of substances originally designed as legal alternatives to more establ

55 irhodium core with variable axial ligands as originally designed by Shionoya et al., provide an excel

56 The "universal" CAS assay originally designed for bacterial siderophores detection

57 quantification protocol combining materials originally designed for dried blood spot analysis with s

58 al adaptations to expand the scope of IDEAL (originally designed for surgical procedures) to accommod

59 Recent technologies originally designed to capture chromatin structure have

60 men's Health Initiative (WHI) hormone trial, originally designed to test effects of hormone therapy (

61 rom a leaf axil meristematic cell population originally detached from the shoot apical meristem.

62 The galaxy cluster XLSSC 122 was originally detected as a faint, extended X-ray source in

63 Selenazoliline (Sez) was originally developed as a masked form of selenocysteine

64 ted zeta inhibitory peptide (ZIP), which was originally developed as a protein kinase C/Mzeta (PKCzet

65 The study proposes lithium titanates, originally developed as Li-ion battery anode materials,

66 ive allosteric modulators (NAMs), which were originally developed as nonsedating anxiolytics and cogn

67 clock models based on the S-System formalism originally developed by Savageau for analysing biochemic

68 The vaccine, originally developed by the Public Health Agency of Cana

69 the application of a drug discovery approach originally developed for cancer called "transcriptome re

70 Moreover, several drugs originally developed for cancer have shown to ameliorate

71 This tool was originally developed for classifying glycomics and glyco

72 Although most SNP arrays were originally developed for domestic organisms, they can be

73 per-resolution microscopy technique that was originally developed for functional imaging of kidney mi

74 Originally developed for gene sets, the same statistical

75 The ESP was originally developed for marine environment applications

76 Here, we have used a technology originally developed for mRNA in vivo delivery to enhanc

77 es might 'recycle' neurocognitive mechanisms originally developed for natural languages.

78 this study is in demonstrating that methods originally developed for particulate matter can also suc

79 -weight DNA molecules using TROSY approaches originally developed for protein applications.

80 wo widely used variant-set tests, which were originally developed for samples of unrelated individual

81 e, using K18-hACE2 transgenic mice that were originally developed for SARS studies(4), we show that i

82 from our previous Deep Learning (DL) method originally developed for soluble protein contact predict

83 ow the adaptation of an alignment algorithm, originally developed for vibrational circular dichroism

84 arch: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of

85 Whilst the originally developed protocols for radical generation re

86 re-purposing the 'size factors,' which were originally developed to account for differences in read

87 terials typically smaller than 100 nm - were originally developed to increase the uptake of chemother

88 Instruments were eligible if they were originally developed to measure the concepts of interest

89 thetic datasets, which is an emerging method originally developed to permit the sharing of confidenti

90 GBS-SNP-CROP is a bioinformatics pipeline originally developed to support the cost-effective genom

91 limab, a monoclonal antibody blocker of CCR5 originally developed to treat HIV-1 infection, was admin

92 analysis" of molecular frameworks, which was originally devised by Corey some 40 years ago.

93 pennanti) in which 37% of hair samples were originally discarded because of uncertainty in individua

94 nged water droplet on the device bridges the originally disconnected components into a closed-loop el

95 Of the 54 originally discordant variants that underwent further re

96 Originally discovered as a TGF-beta-activated kinase, ov

97 Fc neonatal receptor (FcRn) was originally discovered as a transport mechanism for IgG f

98 While originally discovered as proteins that block receptor-G

99 opologically associating domains (TADs) were originally discovered empirically in low-resolution Hi-C

100 Genetic loci harboring four genes originally discovered for their photoperiodic effects (H

101 K-PPn was originally discovered in budding yeast (Saccharomyces ce

102 guanine-nucleotide exchange factor that was originally discovered in neutrophils and is regulated by

103 The nematode Halicephalobus mephisto was originally discovered inhabiting a deep terrestrial aqui

104 1) is a protein of unknown function that was originally discovered through its interaction with argin

105 g protein 1 (Fnip1) is a cytoplasmic protein originally discovered through its interaction with the m

106 he small-bodied cool water slimy sculpin was originally distributed broadly throughout the network an

107 he neurocranium of sarcopterygian fishes was originally divided into an anterior (ethmosphenoid) and

108 The association of SSaDV with SSWS was originally drawn from metagenomic analysis, which was fu

109 e derived through modeling analogous to that originally employed.

110 depends on the occupation of Fe atoms on the originally empty 4d site.

111 only occur for the specific images that were originally encountered.

112 During the trial (which originally enrolled 1791 participants), the separation o

113 itial difference between the alpha cells was originally envisaged as a random imbalance from "noise"

114 They were originally envisaged as a tobacco cessation aid, but whe

115 Originally envisioned for precision spectroscopy of the

116 ss of a discrete and punctuated process than originally envisioned.

117 Lymphomas trial, iPET scans of 596 patients originally evaluated using the DeltaSUV(max) method were

118 uman-biting in this important disease vector originally evolved as a by-product of breeding in human-

119 nd other indirect benefits co-opt strategies originally evolved for mind-reading, and that this model

120 results strongly suggest that asexual thalli originally evolved via apomeiosis in sporophytic thalli.

121 logy of sea star wasting syndrome (SSWS) was originally explored with virus-sized material challenge

122 ected by the viral strain the individual was originally exposed.

123 "Targeted cancer therapy" originally focused on inhibiting essential tumor surviva

124 Originally formulated to explain the temperature depende

125 Our group originally found and cloned cDNA for a 98-kDa type 1 tra

126 pe 1 innate lymphoid cells (ILC1s) have been originally found as liver-resident ILCs, their pathophys

127 are thought to have preserved the icy grains originally found in the interstellar medium prior to sol

128 release strain was developed using a strain originally from Cuba, then outcrossed to a Mexican popul

129 He was originally from north Sudan and eventually moved to Saud

130 yridis (Pallas) (Coleoptera: Coccinellidae), originally from the east Palearctic, has now spread acro

131 Antibiotics were derived originally from wild organisms and therefore understandi

132 sible that the observed part of Phaethon was originally hydrated and has since lost volatiles from it

133 erminal center response, a phenotype that we originally hypothesized to occur in a B cell-intrinsic m

134 Ten multimorbidity patterns were originally identified and two more states (death and dro

135 BCCIP was originally identified as a BRCA2 and CDKN1A/p21 interact

136 BCCIP was originally identified as a BRCA2 and p21 interacting pro

137 The key iron regulatory hormone hepcidin was originally identified as a cationic antimicrobial peptid

138 The Hippo-Yap/Taz pathway, originally identified as a central developmental regulat

139 Although CRIg was originally identified as a macrophage receptor for bindi

140 we show that syntaphilin (SNPH), a molecule originally identified as a negative regulator of mitocho

141 ding, embryonic stem cell-specific-protein), originally identified as a protein capable of binding 5-

142 in 3 (TIM3), a member of the TIM family, was originally identified as a receptor expressed on interfe

143 TARK1 was originally identified as a target of the Xanthomonas euv

144 miR-146a was originally identified as an anti-inflammatory microRNA t

145 Here, we show that Combover (Cmb), originally identified as an effector of planar cell pola

146 al isolates from patients with aspergillosis originally identified as Aspergillus nidulans (section N

147 in RTTN, encoding the protein rotatin, were originally identified as cause of polymicrogyria, a cort

148 However, many genes were originally identified based on candidate-gene studies th

149 Aerobic glycolysis, originally identified by Warburg as a hallmark of cancer

150 olycystin-1 (PC1) is a transmembrane protein originally identified in autosomal dominant polycystic k

151 ce marker (Trop-2) is a surface glycoprotein originally identified in human placental tissue and subs

152 (ZIKV) is a mosquito-transmitted Flavivirus, originally identified in Uganda in 1947 and recently ass

153 been reported that a GM-CSF->CCL17 pathway, originally identified in vitro in macrophage lineage pop

154 onse (ESR), a global transcriptional program originally identified in yeast, is characterized by a ra

155 Methyl-coenzyme M reductase (MCR) has been originally identified to catalyse the final step of the

156 anscription factors Achi/Vis and for a motif originally identified under tMAC ChIP-seq peaks.

157 VR, 87%; P=0.54) or in the survival with the originally implanted pulmonary valve (Melody group, 80%;

158 apinised vaccine viruses that were developed originally in Korea appears to be more similar to the kn

159 view, we adopt the concept of ETI formulated originally in the context of plant pathogens and their h

160 Originally inspired by neurobiology, deep neural network

161 vestigated whether the sex distorter I-PpoI, originally integrated in the A. gambiae genome, could be

162 In our experiments originally intended to create an inducible whole-body SD

163 It was originally interpreted as a chaetognath [1], but it was

164 Furthermore, the thermodynamic metric originally introduced to identify the accept/reject stat

165 These mutations were originally introduced to increase the expression of the

166 eels(11-14)-which have hard and soft layers, originally introduced via the folding and forging techni

167 Modulated nanoindentation (MoNI) was originally invented to measure the radial elasticity of

168 tni partial loss-of-function mutant that was originally isolated based on altered leaf shape, activit

169 Brucella neotomae, originally isolated from the desert pack rat, presented

170 Thirteen Prevotella strains, originally isolated from the human oral cavity, amniotic

171 ation of an amphipathic peptide, arenicin-3, originally isolated from the marine lugworm Arenicola ma

172 Gallinamide A, originally isolated with a modest antimalarial activity,

173 Originally, it was thought that 14-3-3beta promotes GLUT

174 Originally k-mer based, such tools often lack sensitivit

175 ith pre-existing potential splice sites that originally lacked a suitable splicing pair to induce new

176 des, even if applied individually, transform originally large unilamellar vesicles into multilamellar

177 ibited the loss of one IS256 copy, which was originally located in the HU-14 noncoding region between

178 The feline model for CHS was originally maintained for ~20 years.

179 not have any indel mutations called from the originally mapped reads but have been shown to contribut

180 A loss-of-function allele of H2-Ob (Ob), originally mapped within the virus infectivity controlle

181 ere, we identified the novel lncRNA GRASLND (originally named RNF144A-AS1) as a regulator of mesenchy

182 chemical and ultrastructural evidence for an originally non-biomineralized, soft-shelled nature of ex

183 Although transcriptional bursting was originally observed decades ago, only recently have tech

184 The Einstein-de Haas effect was originally observed in a landmark experiment(1) demonstr

185 re topics of intensive current research-were originally observed in various weird and wonderful trans

186 rafish lines (NHGRI-1, kca33Tg, and kca66Tg, originally obtained from ZIRC).

187 , 27.2% Mediterranean, and 18.4% Paleo diets originally, only 54% (IF), 57% (Mediterranean), and 35%

188 c field to engineer the domain structures of originally opaque rhombohedral Pb(Mg(1/3)Nb(2/3))O(3)-Pb

189 uce that these cloudinids were predominantly originally organic (chitinous or collagenous), and postm

190 il and extant diapsid eggshells clusters the originally organic but secondarily phosphatized Protocer

191 parsimoniously be assigned to annelids with originally organic tubes.

192 ed within delicate, dwelling tubes that were originally organic.

193 d on patients who completed 12 months of the originally planned 24-month study.

194 nticipated deaths observed (about 73% of the originally planned 88% power needed for significance), 4

195 This link was originally postulated by Rosenfeld in 1977 [Rosenfeld Y

196 olds for bis(cyclotryptamine) alkaloids were originally postulated in the 1950s, but only four of the

197 Despite originally predicted as an RNA binding domain, its molec

198 such an HZ would be considerably wider than originally predicted given revised CO(2) limits and (for

199 opagation is the energy transfer between the originally prepared excitons and surface plasmons, with

200 with the connectivity of the organic linker originally present in the crystal.

201 sometimes losing almost all genes that were originally present on their X or Z counterparts.

202 protein expression and is more complex than originally presumed.

203 eady exposed on the C. neoformans cell wall (originally produced by CnChs3 and CnCda1 to 3) or releas

204 nsiderably different form and timescale than originally projected.

205 Finally, we update the originally proposed "two-step" model of thymic T(reg) di

206 ical carboxylation of o-alkylphenyl ketones, originally proposed by Murakami et al. (J.

207 st certainly little to do with the structure originally proposed by the isolation team.

208 accurately describes the structure than the originally proposed cubic one.

209 loy a nonparametric Bayesian method that was originally proposed for genetic prediction of complex tr

210 types additionally to the expression levels, originally proposed for these methods.

211 logous to the classic proofreading mechanism originally proposed for tRNA synthase; however, because

212 nitial synthesis campaign had shown that the originally proposed structure is incorrect, the publishe

213 tory after several years from when they were originally proposed.

214 The originally published article contained an error in Figur

215 In Box 4 of the originally published article, the text describing the Mi

216 The version of this paper originally published contained an incorrect unit abbrevi

217 The version of this paper originally published contained reference errors.

218 The version of this paper originally published contained typesetter-introduced err

219 the protocol for using this tool (v.8.0) was originally published in 2013, there have been substantia

220 The version of this paper originally published online contained an error in the x-

221 y, as originally reported, together with the originally published panels, for completeness and transp

222 In the version of this Article originally published the same blot was inadvertently pre

223 This Article was originally published under a CC BY-NC-SA 4.0 license, bu

224 This Article was originally published under Nature Research's License to

225 dated online [insert date]: This article was originally published under standard licence, but has now

226 This article was originally published under standard licence, but has now

227 In the originally published version of this article, the compet

228 ertently omitted from the author list in the originally published version of this article.

229 The version of this article originally published was not open access.

230 ersion of the Supplementary Information file originally published with this Article, the images used

231 In the version of this Article originally published, a technical error meant two proof

232 In the version of this article originally published, an author was missing from the aut

233 In the version originally published, an incorrect version of Figure 1 w

234 In the version of this article originally published, author Joshua R.

235 In the version of the article originally published, extra lines were displayed in Fig.

236 In the version of this Perspective originally published, Fig.

237 In the HTML version of this Article originally published, Fig.

238 In the version of this paper originally published, Figure 4a contained errors that we

239 In the version of this Article originally published, in Fig.

240 In the version of this Article originally published, in the first sentence of the secon

241 In the version of this paper originally published, one of the affiliations for Domini

242 In the version of this News & Views originally published, owing to production error, the con

243 In the version of this Article originally published, references were missing from the c

244 In the version of this article originally published, some cases that were presented in

245 In the version of this Article originally published, Supplementary Fig.

246 In the version of this Article originally published, the affiliation for author Catheri

247 In the HTML version of the article originally published, the author group 'The Schizophreni

248 In the version of this Article originally published, the authors inadvertently cited re

249 In the version of this Article originally published, the authors inadvertently included

250 In the version of this Comment originally published, the authors omitted a funding sour

251 In the version of this Letter originally published, the Methods incorrectly stated tha

252 In the version of this article originally published, the name of co-author Marc C.

253 In the version of this Comment originally published, the name of the author of ref.

254 In the version of this paper originally published, the present address of W.A. McEwan

255 In the version of this Article originally published, the rate of change plotted in Figu

256 In the version of this article originally published, the reference citations in the Met

257 In the version of this article originally published, there was an error in the abstract

258 In the version of this article originally published, there was an error in the second-t

259 In the version of this Article originally published, there were errors in the colour or

260 In the version of this article originally published, Ulrich Steidl's name was listed as

261 The group originally randomized to active iTBS (4-weeks active iTB

262 erior outcomes at one year compared to those originally randomized to sham (2-weeks active iTBS); log

263 Of 235 patients originally randomized, 120 patients had AMI with shock.

264 ight loss of at least 5% after 1 year, those originally randomly assigned to metformin had the greate

265 In communities that had originally received azithromycin and continued receiving

266 Originally recognized for their ability to hydrolyze pen

267 Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-re

268 r formation from 6-membered oxanickelacycles originally reported by Hillhouse.

269 These differed from the originally reported HBoV1 reference strain in 32 nucleot

270 dro-3H-cyclopenta[c]quinoline-8-sulfonamide, originally reported to lack activity when used as a race

271 GBA motif-containing proteins were originally reported to modulate G proteins by binding Ga

272 The discovery of 8 was built upon our originally reported, fragment-derived lead 1 and the rec

273 ated with weight-loss perturbations only, as originally reported, together with the originally publis

274 (2) )[Mn(CO)(3) ](2) resulted from loss of M originally residing in the N(2) S(2) (4-) pocket, replac

275 raphical analyses in BioGeoBEARS of over 100 originally sampled Cyrtognatha individuals, using models

276 re linearly proportional to the blood volume originally sampled onto the DBS card.

277 A cohort of 1,097 individuals originally seen as new patients in a dental school clini

278 the caveat that the study did not reach its originally selected sample size.

279 eds of the ensuing reproductive phase it had originally set into motion.

280 Our model, originally shaped by detailed constraints in the spatial

281 lycemic drugs on HF outcomes, which were not originally specified as the primary end point of the tri

282 ne where coronavirus disease 2019 (COVID-19) originally spread.

283 These originally stationary cells readily turn motile on the u

284 cin B (2) was developed by reconsidering the originally suggested polar transformations of their biog

285 r ecotone by resurveying 106 sites that were originally surveyed for avian diversity in the early 20t

286 tion, and pneumonia, the three conditions it originally targeted.

287 herol, Beta-Carotene Cancer Prevention) that originally tested vitamin E and beta-carotene supplement

288 hat more of the genome encodes proteins than originally thought possible.

289 While it was originally thought that the pool of latently infected ce

290 ological recordings, we found that what were originally thought to be distinct areas in this region (

291 Originally thought to be largely innate, the discovery o

292 Although originally thought to be silent chromosomal regions, cen

293 d that the human genome is more diverse than originally thought.

294 lation was significantly greater in patients originally treated with RFC (3.3+/-1.3 versus 2.5+/-1.5;

295 At reablation, patients originally treated with the cryoballoon had significantl

296 ecies continue to inactivate catalase on the originally triggered cells and on adjacent cells.

297 cies, A. agassizii and A. drachi, the latter originally used as the outgroup.

298 PcG function was originally viewed as being solely repressive and irrever

299 We concentrate on the mouse retina-originally viewed as homogenous-in which genetic labelin

300 e were largely congruent with those elicited originally with 10-15 year olds.