ライフサイエンスコーパス: origination

1 of which may be influenced by their mode of origination.

2 ctivated T cells to home to the tissue of DC origination.

3 with Asia being a center for early mammalian origination.

4 onse, accompanied by an increase in rates of origination.

5 ogeneity in viral load assessment and sample origination.

6 ene sets based on their time of evolutionary origination.

7 es were found in the full and ABC2 structure origination.

8 inciples from that of evolutionary cell-type origination.

9 cific, either through immigration or in situ origination.

10 hape the evolution of the genome by new gene origination.

11 uch as gene birth via duplication or de novo origination.

12 ker Tyrp1, thus supporting their melanocytic origination.

13 rphological traits and long recurrent hybrid origination, A. zhejiangensis does not initiate speciati

14 ost-Cambrian decline in frequency of ordinal origination among serially constructed Bilateria, such a

15 correlate positively with increased rates of origination and broadly with total species diversity.

16 rk for robustly testing scenarios of ancient origination and codiversification versus recent originat

17 gination and codiversification versus recent origination and diversification by host switches.

18 cies are emergent structures and extinction, origination and diversity are entirely a consequence of

19 Patterns of origination and evolution of early complex life on this

20 omes herein provides new clues regarding the origination and evolution of the diverse sex-determining

21 However, the timing of their origination and expansion remains disputed.

22 served marine sedimentary basins to rates of origination and extinction among Phanerozoic marine anim

23 explicit approach that incorporates not only origination and extinction but immigration, a global ana

24 approximately = 5 million years), changes in origination and extinction do not persist for longer tha

25 To answer this question, we estimate the origination and extinction dynamics of fossil marine biv

26 Here, we present a dissection of origination and extinction in epicontinental seas versus

27 M coincided with a prominent increase in the origination and extinction of calcareous phytoplankton.

28 e unimodal, with long and nearly symmetrical origination and extinction phases.

29 dvanced probabilistic methods for estimating origination and extinction rates and a Bayesian method f

30 We show that origination and extinction rates are governed by fundame

31 We find that origination and extinction rates are regionally heteroge

32 f spatial sampling biases and infer regional origination and extinction rates corrected for temporal

33 We investigated how uneven origination and extinction rates drive diversification s

34 e temporal covariance structure of per-genus origination and extinction rates for global marine fossi

35 m, we find significant autocovariance within origination and extinction rates, as well as covariance

36 or impact on previously published background origination and extinction rates.

37 ed by early origins under a range of species origination and extinction rates.

38 ertebrate tree exhibit nearly equal rates of origination and extinction, providing some of the first

39 ty-through-time arises from the interplay of origination and extinction, the processes that shape mac

40 ed by exceptionally high background rates of origination and extinction, were vulnerable to global en

41 to-I RNA editing events in primates, but the origination and general functions of these events are no

42 t have shed light on the process of new gene origination and have contributed to an emerging comprehe

43 ution, summarizing the main evidence for the origination and importance of new genes in evolution.

44 tent with this scenario of relatively recent origination and localized host switches.

45 axon-specific mechanisms that regulate their origination and persistence.

46 osaurs are characterized by reduced rates of origination and phenotypic evolution and their elevated

47 Thus, Pard3 plays a critical role in the origination and separation of zebrafish eye fields and r

48 ilepsy (TLE) is characterized by stereotyped origination and spread pattern of epileptogenic activity

49 provide an ecological signature of the first origination and subsequent loss of disparate morphologie

50 cular clock estimations of an early Cambrian origination and subsequent Ordovician radiation of Bryoz

51 anisms to the rates and patterns of new gene origination and the roles of new genes in phenotypic evo

52 distinctive to birds, for which evolutionary origination and transformation can be understood on the

53 wnian bridge model that estimates the age of origination and, where applicable, extinction through a

54 ng germline gene expression influence operon origination and/or maintenance.

55 The central role of the hypothalamus in the origination and/or processing of feeding-related stimuli

56 These concurrent plant and mammal originations and body-mass shifts coincide with warming

57 have higher rates of diversification, clade origination, and clade dispersal.

58 to species-level ecological factors, time of origination, and phylogenetic relationships.

59 s is environmentally driven extinction, with origination being an opportunistic response to diminishi

60 In keeping with their high rates of origination, both the ammonoids and conodonts rediversif

61 porting the cultivator model of de novo gene origination by demonstrating how the appearance of newly

62 Rates of species origination, by contrast, are not correlated with corres

63 rees S(7)) dispersal from a northern Tethyan origination center.

64 Indeed, originations coincide with mid-Miocene cooling and the s

65 verned by fundamentally different processes: originations depend on within-group diversity but are la

66 family evolution describes patterns of gene origination, diversification and loss within multigene f

67 Upon origination, duplicates tend to maintain their ancestral

68 ionary pattern (extinction, continuation, or origination) during this interval [12].

69 iodiversity change, but their importance for origination dynamics remains untested.

70 hrough the two subspecies after two distinct origination events.

71 cedented opportunities to understand de novo origination events.

72 mputational structural modeling to study the origination, evolution, and protein structures of lineag

73 ty of postulated divergence times depends on origination, extinction, and preservation rates estimate

74 nts are underlain by complex combinations of origination, extinction, and shifts in geographic distri

75 , including few shared oncogenic drivers and origination from both the fallopian tube epithelium (FTE

76 tions in the rearranged Ig genes, indicating origination from naive B cells.

77 Recent studies reveal that de novo gene origination from previously non-genic sequences is a com

78 st as engineering materials because of their origination from renewable resources combined with their

79 age evolutionary dynamics, such as age since origination, historical extinction filters and speciatio

80 he presence of a survival interval, with few originations, immediately after an extinction and preced

81 ins, extend our understanding of GAIN domain origination in adhesion GPCRs and provide insights into

82 this possibility in the case of blast crisis origination in CML.

83 natomically separate and distinct from their origination in different retinal ganglion cell types, th

84 DNA intermediates (DNA-level) or by de novo origination in Drosophila.

85 tic cells in which cancer develops or cancer origination in primitive stem cells closely related to t

86 ate content of sediments induced accelerated origination in reef corals and carbonate-associated bent

87 of early germline cells in the de novo gene origination in testis.

88 in pistil, which is crucial for sexual organ origination in the appropriate location.

89 lum in the modern, and have been since their origination in the early Palaeozoic.

90 icant covariance only between extinction and origination in the immediately following intervals.

91 eject an explosive model of placental mammal origination in the Palaeogene(8) and show that crown Pla

92 on the relationship between temperature and origination in the previous literature.

93 of TE load reduction by suppressing element origination in their independent adaptation to a new env

94 Reduction in ordinal origination indicates increased constraint on arthropod

95 that the driving mechanism for blast crisis origination is a cooperation between specific cell types

96 However, de novo gene origination is challenging to study as it requires high-

97 Greater decline in arthropod ordinal origination is not predicted by ecologic, diversity-depe

98 A genomic pattern of new gene origination is often dependent on a genomic method that

99 ithin orders, indicating that the pattern of origination is self-similar across at least three taxono

100 A direct approach to investigating new gene origination is to examine recently evolved genes.

101 on we assume a constant rate of binding site origination lambda and a constant per site decay rate of

102 However, their origination mechanism remains perplexing, and whether TI

103 that TEs provide a natural mechanism for the origination miRNAs that can contribute to regulatory div

104 as well as covariance between extinction and origination, not one, but two, intervals later, corrobor

105 cates that the onshore preference of ordinal origination occurred only in the Mesozoic prior to the T

106 The present review focuses on anomalous origination of a coronary artery from the opposite sinus

107 Patients symptomatic of anomalous origination of a coronary artery from the opposite sinus

108 anisms responsible for ischemia in anomalous origination of a coronary artery from the opposite sinus

109 le evolutionary steps leading to the de novo origination of a taxon-restricted gene, SCREP, specific

110 For instance, the probability that the origination of an order also begins a new class is a dec

111 million years ago (Ma) and a molecule-based origination of at least 300 Ma.

112 ter, in the Cretaceous and Cenozoic, ordinal origination of benthic organisms did not occur exclusive

113 Several models for the origination of biofilm microstructure are considered, in

114 The origination of both the W and Z from the Y was permitted

115 ed with different mechanisms, including: the origination of bulk catastrophic optical damage (COD) du

116 the emergence of novel traits, that is, the origination of complexity.

117 ts, our results support a scenario of recent origination of coronaviruses in bats and diversification

118 ylogeny and the estimated time frame for the origination of current P. vivax populations are consiste

119 suggest that the combination of size-biased origination of families and parallel size increases amon

120 uplication is an important mechanism for the origination of functional novelties in organisms.

121 The estimated rate of origination of fusion genes in the Oryza genus is as hig

122 ene evolution and provides a hotspot for the origination of genetic novelties such as de novo genes,

123 ales, including ancient events predating the origination of genus-level diversity.

124 Origination of Grx1(as) and Grx1 from the same gene was

125 enza viruses (AIVs) have been pivotal to the origination of human pandemic strains.

126 try of the interchange was not due to higher origination of immigrants in South America as previously

127 ription of the retrocopies often lead to the origination of in-frame proteins relative to the parenta

128 pproximately 1.3 x 10(-8)/year and a rate of origination of lambda approximately 1.6 x 10(-7)/year.

129 We further demonstrate the origination of MA-TAMs from peripheral blood, as well as

130 tazoan phylogeny demonstrates that the rapid origination of major metazoan bodyplans during the late

131 The origination of many modern mammal lineages overlapped wi

132 y shaped by ecologic factors rather than the origination of morphologic novelty alone.

133 cted, indicating an apparent slowdown in the origination of new alleles.

134 ale-dependence is caused by the preferential origination of new families possessing initially larger

135 The origination of new genes contributes to phenotypic evolu

136 s a key developmental process underlying the origination of newly evolved genes.

137 American mammals toward the south, 2) higher origination of North American immigrants in South Americ

138 f A. duranensis may have occurred during the origination of peanut.

139 To better understand the origination of pesticide residues in urban runoff, we in

140 The model estimates the origination of placentals in the Late Cretaceous, with o

141 utation site as a favorable location for the origination of robust A-to-I editing events.

142 TGF-beta isoform signaling may suppress the origination of secondary transition endocrine cells from

143 urthermore, we can trace the apparent recent origination of several evolutionarily novel immune-relat

144 The former may correspond to the origination of slow wavefronts of reexcitation and phase

145 activity still needs to be boosted, and the origination of spin-related oxygen catalytic performance

146 tive first-order neurons are involved in the origination of the baroreceptor reflex, they suggest tha

147 lls, which in turn can constrain the mode of origination of the eucelom.

148 One of the difficulties lies in dating the origination of the family, a particularly challenging ta

149 The apparent origination of the R domain de novo from previously non-

150 ritical functions, including egg activation, origination of the zygote centrosome and delivery of pat

151 ds into the sessile lophotrochozoans and the origination of their bivalved bauplan preceding the biom

152 ns in ancient paralogs probably reflects the origination of these genes during the earliest phase of

153 Phylogenetic analysis implies a recent origination of these ILTPSs from a GGDPS progenitor in f

154 o, raising questions about tempo and mode of origination of this key developmental feature.

155 , neutral speciation-extinction (of species)-origination (of genera; SEO) model for macroevolutionary

156 red unexpected and intriguing facets of gene origination, offering novel perspectives on the complexi

157 t rejected for marine diversity, accumulated origination or accumulated extinction, suggesting that e

158 s is actually associated with lower rates of origination over evolutionary time.

159 The pervasive role of spatial origination patterns in shaping LDGs, regardless of the

160 We identified 100 NDGs, showing clear origination patterns, whose parental genes are located i

161 Simulations were examined for origination points within one degree of capture location

162 Here, we show that origination probability in marine fossil genera is stron

163 Overall, origination probability increases by 27.8% [95% CI (27.4

164 A single origination pulse may be present at 2.0-1.75 Ma, but bes

165 mutation is the mutation of highest de novo origination rate and deviates most from the genome-wide

166 ify five major episodes of species turnover (origination rate plus extinction rate) that were coincid

167 the cross-correlation between extinction and origination rates across the entire Phanerozoic marine f

168 revealing new patterns and rules with stable origination rates across various organisms.

169 this spatial pattern indicates that tropical origination rates after the K/Pg event have left a perma

170 ental fragmentation, has a similar effect on origination rates as paleoclimate interactions, supporti

171 The data also confirm that extinction and origination rates both declined through the Phanerozoic

172 h which paleoclimate interactions can act on origination rates by additionally examining a proxy for

173 maxima in standing genus diversity and genus origination rates coincide spatially.

174 nger than one interval, except that elevated origination rates immediately after extinction may last

175 Regional origination rates increased abruptly above this boundary

176 We find no differences in the dispersal and origination rates of immigrants.

177 ation rates, but instead are correlated with origination rates roughly 10 million years later.

178 extinctions but not at other times and that origination rates were significantly higher in open-ocea

179 estimate marine invertebrate extinction and origination rates with much greater accuracy.

180 ing temperatures also predict extinction and origination rates, alongside other abiotic and biotic pr

181 ignificantly correlated with contemporaneous origination rates, but instead are correlated with origi

182 The break reflects a permanent increase in origination rates, intermediate between the Mesozoic rat

183 tinction rates causally increased brachiopod origination rates, suggesting that bivalves have suppres

184 al of ~1 Ma, initially co-occurring with low origination rates.

185 xtinction rates are followed by equally high origination rates.

186 eral role of gene fusion as part of new gene origination remains unknown.

187 s change in environmental pattern of ordinal origination roughly correlates with Late Cretaceous: (i)

188 r this cancer in general, independent of the origination site in the lung.

189 rrence of basal dendrites, and abnormal axon origination sites.

190 may be a primary mechanism to facilitate the origination, survival, and regulation of genes derived f

191 indicate that the anomalous LDG results from origination that is damped in the tropics rather than he

192 insights into the mechanism of de novo gene origination, the role of transposable elements in gene e

193 1 IAV as an alternative to the hypothesis of origination through an intrasubtype reassortment.

194 actions in governing rates of extinction and origination through geological time remains unknown.

195 lion years for the diversity and accumulated origination time series.

196 We extend current predictions on origination times for crown- and total-groups, and extin

197 the plausible interval for placental mammal origination to the younger range of molecular clock esti

198 ecies diversification, and the importance of origination versus extinction in driving evolutionary dy

199 However, this high rate of origination was offset by low genetic isolation, and low

200 aracterized by much lower intrinsic rates of origination, were held at low levels of diversity by the

201 De novo gene origination, where a previously nongenic genomic sequenc

202 port the existence of this mechanism of gene origination, which we named "start-snatching." Depending

203 els and early transcription were favoured in origination with a stepwise formation of gene structure.

204 hat precisely defines the site of transcript origination within thousands of human promoters.

205 gene order that has had multiple independent originations within birds, based on sampling of 137 spec

206 n age structure for serviceberry showing the origination year of stems in a northern range study area

207 The ventral tegmental area (VTA) is the origination zone for dopaminergic neurons involved in re