ライフサイエンスコーパス: orthologous

1 genes underlying these changes are often not orthologous.

2 nces in vivo, we generated mice in which the orthologous 10-kb intronic sequences were removed.

3 e investigated the effects of homologous and orthologous active-site mutations on both stability and

4 -17, miR-18, miR-19 or miR-25 families in an orthologous ADPKD model.

5 Our orthologous analysis of lncRNAs in human and rat brain t

6 Here, we performed an orthologous analysis of lncRNAs in human and rat brain t

7 RP-type and sNPF-type signalling systems are orthologous and originated as a paralog of NPY/NPF-type

8 ncing diverse genomes allowed the tracing of orthologous and paralogous genes to understand the co-ev

9 et of gene families to allow traversal among orthologous and paralogous sequences across the legumes.

10 eoxy-d-glucose (2DG) on ADPKD progression in orthologous and slowly progressive murine models created

11 In addition to allelic variation, abundant orthologous and species-specific KIR genes were identifi

12 RH-type and the protostomian AKH systems are orthologous and the origin of a paralogous CRZ-type sign

13 henotype that is rescued by expression of an orthologous antitoxin, DarG(Taq) , from Thermus aquaticu

14 Our orthologous approach also enabled a screen combining gen

15 structure of the equivalent region from the orthologous barley powdery mildew resistance protein, ML

16 Human and mouse genomes contain pairs of orthologous bitter receptor genes that have been conserv

17 It is assumed that the orthologous bitter taste receptor genes mediate the reco

18 Moreover, we have demonstrated that sequence-orthologous bitter taste receptors have distinct agonist

19 uncating variants in transiently transfected orthologous cells and cultured hippocampal rat neurons r

20 he similarity dropping sharply compared with orthologous charophyte sequences.

21 We investigate its divergence from orthologous chimpanzee and modern human sequences and fi

22 large interspersed duplication blocks at non-orthologous chromosomal locations in each primate lineag

23 Remarkably, we found orthologous cis-regulatory elements associate with wing

24 that facilitate the comparative analysis of orthologous clusters among up to 12 species.

25 the comparison and analysis of whole-genome orthologous clusters.

26 Together, these data support a role for non-orthologous commensal-host cross-reactivity in the devel

27 that substrate recognition is different than orthologous complexes.

28 nerability in Ewing sarcoma cells, providing orthologous confirmation of the chemical screen findings

29 Macaca mulatta (macaque), as well as perform orthologous conversions among the supported species.

30 se morpholino oligonucleotides to target the orthologous Danio rerio gene, dlx4b, and found reduced c

31 of conditionally degradable or stabilisable orthologous dCas9 or Cpf1 effector proteins, thus openin

32 from the protection provided by molecularly orthologous defenses from another species.

33 ological traits in mice carrying the 16p11.2 orthologous deletion or duplication, as well as Bola2(+/

34 er replacement of the genes pgi or tpiA with orthologous DNA from donor species spanning all domains

35 e alignment accuracy of TFBS families within orthologous DNA sequences.

36 e and conservation of surface residues among orthologous domains, we mapped the BMP-binding epitope o

37 ing events based on the DNA specificities of orthologous Dre and Cre recombinases.

38 racterized OCR-4 TRPV subunit as well as the orthologous Drosophila Nan-Iav TRPV channel, and we exam

39 ssays to show that transport activity of the orthologous endosomal NHE Nhx1 is important for multives

40 Homozygous deletion of the orthologous enhancer region in 832/13 cells resulted in

41 Finally, we show that snake and mouse orthologous enhancer sequences can display distinct expr

42 Finally, DeepMEL identifies orthologous enhancers across distantly related species,

43 (2) Enhancer in-vivo activity, revealing orthologous enhancers with conserved activity despite di

44 per neutral site), identifying thousands of orthologous enhancers with conserved or diverged combina

45 e relatedness of the enzyme complex with the orthologous enzymes in archaea.

46 nction of Pam18 has been replaced by the non-orthologous euglenozoan-specific J-protein TbPam27.

47 tterning with concomitant attenuation of the orthologous expression of tcf3a/b, encoding a binding pa

48 notype in mice that are heterozygous for the orthologous factor, impeding the study of complex phenot

49 ctional annotation of gene models identified orthologous families for the majority ( approximately 73

50 e previously developed a mouse model that is orthologous for a known patient mutation in Asah1 that r

51 zed R405W-desmin knock-in mice harboring the orthologous form of the human R406W-desmin.

52 ional changes led to a reduced expression of orthologous functions between the coexisting species.

53 fferent species, which we term topologically orthologous functions.

54 omology-directed recombination to harbor the orthologous Gaa mutation c.1826dupA (p.Y609*), which cau

55 lly, while the mammalian genome contains two orthologous Gcm genes, their function has been demonstra

56 c knockdown or overexpression of each single orthologous gene (Da, Mef2, Ube3a, Zfh1, XNP) and in pai

57 Using the orthologous gene alignments created, we assessed bat phy

58 nd produce an advanced pipeline for curating orthologous gene alignments from combined transcriptomic

59 ecies, each of which is represented in 1,107 orthologous gene alignments used to build the tree.

60 s, Pereskia We used these to construct 4,436 orthologous gene alignments.

61 ximum likelihood phylogenetic trees for each orthologous gene and corresponding 16S rRNA reference sp

62 osed a method that explains the evolution of orthologous gene blocks (orthoblocks) as a combination o

63 Our phylogenetic analysis based on 2148 orthologous gene clusters from all isolates is consisten

64 Defining syntenic relationships among orthologous gene clusters is a frequent undertaking of b

65 Genome-wide patterns of orthologous gene content covary with rrn copy number, su

66 eterozygous loss-of-function mutation of the orthologous gene exhibit alterations in axonal branching

67 e conserved between humans and mice based on orthologous gene expression.

68 osotalea genomes contained a core set of 103 orthologous gene families absent from all other ammonia-

69 pecies ca. 60 Mya, only 35% of the ancestral orthologous gene families from the cyanobacterial endosy

70 lifestyle led to the simplification of many orthologous gene families involved in the saprophytic tr

71 s database represents a comprehensive set of orthologous gene families shared across multiple complet

72 Orthologous gene identification is fundamental to all as

73 We show that deletion of the orthologous gene in yeast (ppa2Delta) compromises cell v

74 findings provide evidence that MtSUP is the orthologous gene of SUP in M. truncatula.

75 n this syndrome, knockdowns of the zebrafish orthologous gene resulted in embryos with hydrocephaly a

76 We used sets of barley and wheat orthologous gene sequences to compare discrete parts of

77 Using thousands of shared single-copy orthologous gene sequences, we fully reconstruct, for th

78 We generated a knockout yeast model for the orthologous gene that showed a defect in respiration and

79 obacterium avium harboring insertions in the orthologous gene whose ability to microaggregate and for

80 e identification of functionally equivalent, orthologous genes (functional orthologs) across genomes

81 py nearby rather than identical positions in orthologous genes (intron sliding or shifting).

82 MCL method identified 11,362 and 8,174 1:1:1 orthologous genes (one ortholog is represented in each o

83 ed the expression dynamics of the conserved, orthologous genes (orthologs), seeing the degree to whic

84 at the majority of orthologs were positional orthologous genes (POGs) with localization on homologous

85 tructed chimeric mRNAs carrying the 3'UTR of orthologous genes and demonstrated that 3'UTR sequence v

86 toxic exposure allows predictions regarding orthologous genes and pathways across phyla.

87 Frequently, for one query gene, multiple orthologous genes are predicted in the other genome, and

88 articular, we found a significant overlap of orthologous genes associated with eQTLs in both species.

89 In some cases, orthologous genes can achieve a similar biological funct

90 s by preferentially regulating expression of orthologous genes for cutin formation, but not wax biosy

91 Recently, a set of orthologous genes found in beta- and gammaherpesviruses

92 patterns across a wide range of tissues with orthologous genes from a pre-Ss4R outgroup unexpectedly

93 lia express a conserved core gene program of orthologous genes from rodents to humans, including liga

94 chmark an empirical collection of 853 1-to-1 orthologous genes from seven yeast species and found wpS

95 s, indicating functional conservation of the orthologous genes in controlling chlorophyll content in

96 While we find that expression profiles of orthologous genes in different species are highly correl

97 ional functions that might be assumed by non-orthologous genes in different species.

98 Comparative analysis of orthologous genes in grain amaranth (Amaranthus hypochon

99 ypic consequences of loss of function of the orthologous genes in mice and medaka fish and further ex

100 Silencing of the WRKY25/22 orthologous genes in Nicotiana benthamiana led to a dela

101 ents and are less likely to be syntenic with orthologous genes in other grasses.

102 itis elegans, knockout of uba-5 and of human orthologous genes in the UFM1 cascade alter cholinergic,

103 finding is that the expression of 476 human orthologous genes in this rat BPA signature robustly pre

104 ate the data from the promoters of conserved orthologous genes in three or more species was developed

105 Identifying orthologous genes is an initial step required for phylog

106 erns observed along differentially expressed orthologous genes of Lepidoptera, we further found that

107 alian immune cells, a subset of which are in orthologous genes of mouse and human, suggests a conserv

108 t classes known in A. thaliana We identified orthologous genes of the relevant A. thaliana genes by s

109 enetic analysis, including identification of orthologous genes or proteins, multiple sequence alignme

110 which different central genes were utilized, orthologous genes played different evolutionary roles, a

111 blished knockouts of the fruit fly and mouse orthologous genes resulted in lethality or severe neurol

112 The 'ortholog conjecture' proposes that orthologous genes should be preferred when making such p

113 (fl/fl) mammary carcinomas and comparison of orthologous genes with a human metaplastic carcinoma sig

114 S. carpocapsae shares orthologous genes with other parasitic nematodes that ar

115 d data, in particular ATGC-COGs (Clusters of Orthologous Genes), multiple sequence alignments, a set

116 l mouse embryos maintained the expression of orthologous genes, and blastocyst development was establ

117 between the physiological roles of seemingly orthologous genes, as xylem loading depends on SKOR and

118 m a DS mouse model duplicated for some Hsa21-orthologous genes, indicating cross-species conservation

119 m species to construct a phylogeny from 9868 orthologous genes, revealing several geographic clades b

120 ged through differences in the regulation of orthologous genes, the formation of new genes by gene du

121 Using 88 single-copy orthologous genes, we reconstructed a fully resolved and

122 of high sequence diversity in the 3'UTRs of orthologous genes.

123 use clustering to exclude multiple copies of orthologous genes.

124 ate recombination and mutation events across orthologous genomes.

125 tating the targeted BAC clones, we generated orthologous genomic sequences surrounding the DEP1 locus

126 Here we show that orthologous grapevine gene expression associate with flo

127 e a more scalable procedure for hierarchical orthologous group (HOG) clustering, which are several or

128 xidative stress by 3D-homology modelling and orthologous group comparisons.

129 Patterns of orthologous group distributions reveal a genetic basis t

130 c domains of CheA and chemoreceptors from an orthologous group exemplified by the Salmonella McpC pro

131 table for interrogating the overlap of each orthologous group for the queried species.

132 pVOGs are constructed within the Clusters of Orthologous Groups (COGs) framework that is widely used

133 a, as well as between and within clusters of orthologous groups (COGs).

134 by several orthology databases, hierarchical orthologous groups (HOGs) are sets of genes that are inf

135 y-based term classification (GO), EuKaryotic Orthologous Groups (KOG) and Kyoto Encyclopedia of Genes

136 In total, 4.4M orthologous groups (OGs) distributed across 379 taxonomi

137 eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at different taxono

138 When proteins are collapsed into orthologous groups (OGs) the resulting meta-interactome

139 The Prokaryotic Virus Orthologous Groups (pVOGs, formerly called Phage Ortholo

140 We also construct a vaginal orthologous groups (VOG) from VIRGO.

141 r structurally from those of mosquitoes, and orthologous groups are nearly impossible to define.

142 tegory of poorly characterized by Cluster of Orthologous Groups classification.

143 00 000 proteins, and the number of conserved orthologous groups doubled to 9518.

144 titled HogProf, which leverages hierarchical orthologous groups for the construction of large profile

145 physiological processes based on Clusters of Orthologous Groups functional categories.

146 The OGCleaner relies on high-quality orthologous groups identified in OrthoDB to train machin

147 in the individual genomes into hierarchical orthologous groups reveals a high-resolution picture of

148 hologs; (v) statically computed hierarchical orthologous groups subsets downloadable in OrthoXML form

149 Out of 885 EuKaryotic Orthologous Groups that we found from outlier SNPs, 294

150 cording to KOG (The annotation of Eukaryotic Orthologous Groups) and KO (KEGG Orthology) in addition

151 ologous Groups (pVOGs, formerly called Phage Orthologous Groups, POGs) resource has aided in this tas

152 y bias towards chemoreceptors from different orthologous groups.

153 acquired from the environment, regulates an orthologous hematopoietic pathway in their host.

154 EER-associated genes contained an EER in the orthologous human gene, although nucleotide sequence and

155 enous H19/Igf2 ICR (mIC1) is replaced by the orthologous human ICR (hIC1) sequence, designated H19(hI

156 ed replacement of mouse genomic regions with orthologous human sequences has become increasingly viab

157 Thus, orthologous hypoxia, heat-shock, and circadian clock pro

158 selection hypothesis, we find that diverged, orthologous IDRs can mostly recapitulate wild-type funct

159 bilizing selection, the functional output of orthologous IDRs could be maintained, such that diverse

160 ep, modelling the proteins, chemicals, their orthologous in other species and their composition in co

161 st proliferation and PKD progression in four orthologous, including two long-lived, mouse models of A

162 h Yap1, a Yorkie homolog, in human cells, an orthologous interaction was not detected in Drosophila c

163 uman co-orthologs was marked by retention of orthologous interactions in functional or protein networ

164 egree to which these can be accounted for by orthologous (internal) versus species-specific (external

165 are preserved in the amino acid sequences of orthologous intrinsically disordered regions.

166 ifferentiation, but not involving the murine orthologous introns or genes.

167 In PV mice that express the orthologous JAK2 mutation causing human PV, administrati

168 t19-8 mutant, which is unable to express the orthologous ligandin AtGSTF12, restored anthocyanin accu

169 An orthologous Ligase C (LigC) complex also co-exists in ma

170 Orthologous loci for resistance to rust pathogens were i

171 ranscripts we identified 749,397 clusters of orthologous loci.

172 espite changes in its gene content, a single orthologous locus (MAT/MTL) has controlled cell type thr

173 Legumes and Parasponia spp. use orthologous LysM-type receptors to perceive rhizobium LC

174 Orthologous mAAV-EVE1 locus sequences from sixteen macro

175 (FLC) and PERPETUAL FLOWERING 1 (PEP1), two orthologous MADS-box TFs that repress flowering and conf

176 ess response, bypassing the need in detailed orthologous mapping.

177 The Orthologous MAtrix (OMA) database is a leading resource

178 y methods have been proposed, including OMA (Orthologous MAtrix).

179 Microorganisms often encode multiple non-orthologous metabolic modules that catalyze the same rea

180 ormed comparative directed evolution of four orthologous metallo-beta-lactamases toward a new functio

181 a benthamiana further reveal a shared set of orthologous microbe-responsive genes that include member

182 we demonstrate cross-reactivity between non-orthologous mimotopes expressed by a common human gut co

183 d kidney injury, and improved survival of an orthologous model of ADPKD.

184 In addition, overexpression of the orthologous mouse allele induced lung adenocarcinoma in

185 omy of all or part of human chromosome 21 or orthologous mouse genomic regions, are providing valuabl

186 and mutation of this conserved motif in the orthologous mouse SRF enhancer revealed decreased SRF ex

187 A search for orthologous mutant alleles in maize confirmed a very sim

188 We introduced the orthologous mutation into a mouse strain by CRISPR-Cas9

189 ology of hyper-IgM syndrome patients with an orthologous mutation, lacked CSR and SHM, and had broad

190 ion through inhibiting histone demethylases, orthologous mutations to those known to cause accumulati

191 icient to distinguish previously unknown and orthologous neuronal subtypes as well as regional identi

192 ell as cross-network moves between potential orthologous nodes with high sequence similarity.

193 defective (Pkhd1(del4/del4)) mouse, which is orthologous of CHF, we show that Pkhd1(del4/del4) cholan

194 Mouse stx promotes degradation of Cbx4, an orthologous Pc protein, in vertebrate cells and induces

195 ly, we generalize the notion of a phenolog ('orthologous phenotype') to use functionally similar prot

196 acterization and difficulties in identifying orthologous phenotypes and cell types, which are beginni

197 onditional expression of Myd88(p.L252P) (the orthologous position of the human MYD88(p.L265P) mutatio

198 h for the presence or absence of clusters of orthologous protein domains and constructed a dendrogram

199 We considered 10,314 unique orthologous protein families and constructed 5,879,879 P

200 ast and metazoans, and a family of conserved orthologous protein O-mannosyltransferases is believed t

201 es are accepted, on average, per site across orthologous protein sequences.

202 The discovery of orthologous protein triads producing related secondary m

203 hylogenetic methods to comprehensive sets of orthologous protein-coding and noncoding regions of the

204 We use alignments of orthologous protein-coding genes from 39 species of bird

205 ligonucleotide composition-based analysis of orthologous proteins (n = 791) across three genomes reve

206 s of animal cells, involving the activity of orthologous proteins [10, 11], we anticipate that our re

207 Orthologous proteins also display extreme divergence in

208 the information of subcellular localization, orthologous proteins and PPI networks, we propose a nove

209 Genetic variation among orthologous proteins can cause cryptic phenotypic proper

210 We find that the three orthologous proteins can substitute for BslA in B. subti

211 Sequence divergence of orthologous proteins enables adaptation to environmental

212 ctions of EspE and EspF are conserved in the orthologous proteins from M. tuberculosis Our findings s

213 -wide comparative analyses of mRNAs encoding orthologous proteins from the genus Staphylococcus and f

214 e estimated scores can be used for detecting orthologous proteins in conserved functional modules thr

215 ere strongly connected through essential and orthologous proteins in their immediate network vicinity

216 vestigations on three Caenorhabditis elegans orthologous proteins involved in this post-translational

217 ding on the cellular and organismal context, orthologous proteins may exert both overlapping and oppo

218 up users' search of detailed information for orthologous proteins related to secretion systems of the

219 we call delta-bitscore (DBS) for identifying orthologous proteins that have diverged at the amino aci

220 Orthologous proteins were also among the enriched protei

221 Such modules typically consist of orthologous proteins with conserved interactions, which

222 cerevisiae) Nucleolar protein53 (Nop53) are orthologous proteins with demonstrated roles as ribosome

223 the information of subcellular localization, orthologous proteins with PPI networks, the accuracy of

224 ng the steady-state network Flow to IDentify orthologous proteins) framework combined with an efficie

225 and apply it to a proof-of-concept study of orthologous proteomes in an investigation of host adapta

226 ergent regulatory mechanisms may exist among orthologous pseudoenzymes.

227 thesized that the introduction of the murine orthologous Ptpn22(R619W) mutation to the NOD genome wou

228 echanisms by generating a mouse model of the orthologous Q140K Abcg2 variant and find male mice have

229 omoter region of the human SLICK (KCNT2) and orthologous rat Slick (Kcnt2) genes, suggesting that con

230 We conclude that divergence of orthologous RdRPs can result in functional innovation wh

231 sociated the occurrence of a functional NFP2-orthologous receptor to LCO-driven nodulation.

232 We used CRISPR/Cas9 to delete the orthologous region in zebrafish in order to test the pat

233 DS, which is duplicated for the entire Hsa21-orthologous region of mouse chromosome 16.

234 The orthologous region was deleted in mice, which resulted i

235 Comparison with orthologous regions from rice, Brachypodium, and sorghum

236 Comparison with orthologous regions from rice, sorghum, and Brachypodium

237 ence-free whole-genome alignment to identify orthologous regions in greater numbers than has previous

238 ted in Sox2-EGFP(+) cells map to over 48,000 orthologous regions in the human genome that include reg

239 veals that PspA orthologs associate with non-orthologous regulatory and effector proteins retaining f

240 The neurodevelopmental roles of orthologous/related mammalian genes suggest a fundamenta

241 in P. axillaris Furthermore, where putative orthologous relationships of ASATs are predicted between

242 ed but scrambled blocks of genes in putative orthologous relationships with other green algae.

243 oexpression networks across species based on orthologous relationships.

244 ntous fungi and by computational analyses of orthologous RNAs from 62 fungal species.

245 Using orthologous self-labelling tags and chemical cross-linke

246 A model of orthologous sequence divergence spanning hundreds of mil

247 ficiently delete and replace the L2-CRM with orthologous sequences from other divergent fly species.

248 l ChIP-seq read depths directly measured for orthologous sequences.

249 causing PPT1 (R151X) human mutation into the orthologous sheep locus.

250 Recent work indicates that SIRT1 and orthologous sirtuins coactivate the oestrogen receptor/E

251 of this phosphorylation mark by mutating the orthologous site of CAP-D3 (CAP-D3(T1403A)) in chicken D

252 ense mutations in BRG1, when placed into the orthologous Sth1 ATPase of the yeast RSC remodeler, sepa

253 We contrast this complex with an orthologous structure from phage lambda, which has a dis

254 The orthologous subunit in yeast is Rev3p.

255 uman genome or exhibit no p63 binding in the orthologous syntenic regions, typifying an occupancy los

256 roteobacterium Caulobacter crescentus and an orthologous system from an obligate intracellular (ricke

257 roximately 10%) of genes are predicted to be orthologous targets.

258 tion of Hordeum vulgare VIVIPAROUS1 (HvVP1), orthologous to ABA-INSENSITIVE3 from Arabidopsis thalian

259 ngle M. polymorpha RKD gene, MpRKD, which is orthologous to all five A. thaliana RKD genes.

260 EG1C, which together with DEG1A and DEG1B is orthologous to Arabidopsis (Arabidopsis thaliana) Deg1 i

261 member of the ChaC family that appears to be orthologous to ChaC2.

262 on of their alternate isoforms, Delta113p53 (orthologous to Delta133p53 isoform in human) and mdm2-P2

263 cally interacting with FRM-3, a FERM protein orthologous to FARP1/2.

264 illustrated that most goldfish markers were orthologous to genes in common carp, which had four roun

265 We show that the yeast Rim15-Igo1,2 pathway, orthologous to Gwl-Arpp19/ENSA, is up-regulated in early

266 trisomies of regions of mouse chromosome 16 orthologous to Hsa21.

267 ccharomyces cerevisiae RecQ helicase Sgs1 is orthologous to human BLM, defects in which cause the can

268 nalysis showed that zebrafish mate genes are orthologous to human MATEs.

269 The Wpk rat model, orthologous to human MKS3, provides a unique platform to

270 These proteins are not orthologous to known proteins, do not contain identified

271 ocus that conditions flower and seed colors, orthologous to Mendel's A gene of garden pea, whose loss

272 esponsible for the diminutive mutant, a gene orthologous to MMS19 with a 36.8 kb deletion co-segregat

273 g that although most algae contain sequences orthologous to plant-like l-Rha biosynthesis machineries

274 ns affected conserved residues, and R291Q is orthologous to R294, which is mutated in the BXH2 IRF8-d

275 and Br140, another bromodomain protein, are orthologous to subunits of a mammalian MOZ/MORF acetyltr

276 tein denoted PPR53 (GRMZM2G438524), which is orthologous to the Arabidopsis protein SOT1 (AT5G46580).

277 Drak), a cytoplasmic serine/threonine kinase orthologous to the human kinase STK17A, as a downstream

278 Drak), a cytoplasmic serine/threonine kinase orthologous to the human kinase STK17A.

279 The maize ROUGH ENDOSPERM3 (RGH3) protein is orthologous to the human splicing factor, ZRSR2.

280 The SMP domain of PDZD8 is functionally orthologous to the SMP domain found in yeast Mmm1.

281 ied alphaTC1/betaTC6 cis-regulatory elements orthologous to those containing type 2 diabetes (T2D)-as

282 ointed out that DRPs of chlorophytes are not orthologous to those of embryophytes: some of them were

283 SCRM1) in the moss Physcomitrella patens are orthologous to transcriptional regulators of stomatal de

284 illi and cilia and express proteins that are orthologous to transporters in microvillar and ciliary o

285 rpholinos against N-terminal zebrafish Ahi1, orthologous to where human mutations cluster, produced a

286 y 84% of markers are in protein-coding genes orthologous to zebrafish proteins.

287 nerating CRISPR/Cas9 knockout mutants of the orthologous tomato gene resulting in light-green tomato

288 The orthologous transcript of Aspergillus niger can be alter

289 a multi-step splicing process occurs in the orthologous transcript, in which a complex intervening s

290 EchinoDB is a repository of orthologous transcripts from echinoderms that is searcha

291 ence is highly conserved within the mRNAs of orthologous transporters in multiple kinetoplastid speci

292 y pathway through conserved targeting of the orthologous Tre-2/Bub2/CDC16 (TBC) Rab GTPase-activating

293 5'ss and 3'ss sequences from the well-known orthologous U12-type spliceosomal intron database U12DB.

294 ed CRISPR-Cas9 to generate mice encoding the orthologous variants and found that compound heterozygos

295 hole-genome duplications, and the concept of orthologous versus paralogous relationships at different

296 ATP1B4 genes represent a rare instance of orthologous vertebrate gene co-option that radically cha

297 lution of repeats within proteins with their orthologous (vertical) evolution through speciation.

298 The chromosomal regions across the human orthologous were interrogated for putative periodontitis

299 The causative mutation maps to a gene orthologous with the third subunit of DNA polymerase del

300 sgenic lines, which were generated using the orthologous ZmSHR1 gene to avoid potential silencing of