ライフサイエンスコーパス: orthostatic

1 l (21.2 percent), cardiac (9.5 percent), and orthostatic (9.4 percent); for 36.6 percent the cause wa

2 tial minority of patients, headaches are not orthostatic and may mimic other types of headache.

3 rtality associated with vasovagal (including orthostatic and medication-related) syncope.

4 ce data and prevalence estimates of impaired orthostatic blood pressure (BP) stabilization, initial o

5 rdiac conduction, ventricular arrhythmia, or orthostatic blood pressure.

6 Orthostatic BP responses in adults aged 50 to 59 years s

7 OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/

8 ume expansion prior to the application of an orthostatic challenge attenuates heat stress-induced red

9 d and is capable of decreasing CVC during an orthostatic challenge in heat-stressed individuals.

10 contributing to reductions in CVC during an orthostatic challenge of heat-stressed individuals.

11 d PPG to ECG for estimation of HRV during an orthostatic challenge performed by 17 subjects.

12 esistance response from the beginning of the orthostatic challenge.

13 ical in maintaining postural stability under orthostatic challenge.

14 preventing blood pressure instability during orthostatic challenges.

15 upper GI cause associated with hypotension, orthostatic changes in heart rate [>20 beats per minute]

16 ed duration of sleep (47 [92%] vs 39 [71%]), orthostatic dizziness (42 [78%] vs 46 [81%]), depression

17 Typical orthostatic symptoms such as orthostatic dizziness and blurred vision, and atypical s

18 autonomic dysfunction (as assessed using the Orthostatic Grading Scale [OGS]) were significantly more

19 An orthostatic headache is the prototypical manifestation b

20 The dominant clinical finding is an orthostatic headache.

21 l fluid (CSF) leaks and is known for causing orthostatic headaches.

22 Attenuated orthostatic HRR may reflect dysregulation of the parasym

23 Speed of orthostatic HRR predicts mortality and may aid clinical

24 ), urinary tract infections (n=9 [11%]), and orthostatic hypotension (n=8 [10%]).

25 In patients with neurogenic orthostatic hypotension (NOH), the availability of the s

26 Patients with Parkinson's disease (PD) and orthostatic hypotension (OH) (PD+OH) or with pure autono

27 arkinsonism and non-motor features including orthostatic hypotension (OH) and cognitive impairment.

28 An association between orthostatic hypotension (OH) and mortality has been repo

29 Review the effect of orthostatic hypotension (OH) and rapid-eye-movement slee

30 rivastigmine is affected by the presence of orthostatic hypotension (OH) in patients with Parkinson'

31 Orthostatic hypotension (OH) is a common cardiovascular

32 Orthostatic hypotension (OH) is a common cause of transi

33 Orthostatic hypotension (OH) is a fall in blood pressure

34 Orthostatic hypotension (OH) is common in elderly people

35 sed on HUT results, we divided patients into orthostatic hypotension (OH), postural tachycardia syndr

36 ease, there are concerns that it might cause orthostatic hypotension (OH).

37 n the heart and other organs, manifesting as orthostatic hypotension (OH; also known as postural hypo

38 measured in patients with PD with or without orthostatic hypotension (PD+OH, PD-No-OH); in patients w

39 It might be possible to improve treatment of orthostatic hypotension acutely with water imbibation an

40 Screening autonomic function tests indicated orthostatic hypotension and confirmed chronic autonomic

41 ide an explanation for the predisposition to orthostatic hypotension and intolerance in well-trained

42 Orthostatic hypotension and parasympathetic dysfunction

43 Both orthostatic hypotension and postprandial hypotension inc

44 anding than before spaceflight, and in some, orthostatic hypotension and presyncope.

45 betes increases the risk of hypertension and orthostatic hypotension and raises the risk of cardiovas

46 Neurogenic orthostatic hypotension and supine hypertension are comm

47 comes in patients with coexistent neurogenic orthostatic hypotension and supine hypertension, clinici

48 isks for patients with coexistent neurogenic orthostatic hypotension and supine hypertension.

49 erapy in patients with coexistent neurogenic orthostatic hypotension and supine hypertension; and the

50 ration, leading to an increased incidence of orthostatic hypotension and syncope.

51 mediate benefits of treatment for neurogenic orthostatic hypotension and the long-term risks of supin

52 zation, initial orthostatic hypotension, and orthostatic hypotension are reported.

53 zation, initial orthostatic hypotension, and orthostatic hypotension based on beat-to-beat blood pres

54 thesis that short-term alcohol intake causes orthostatic hypotension because of an impairment in the

55 Orthostatic hypotension can reflect altered activity of

56 In Parkinson disease, orthostatic hypotension can result from L-dopa treatment

57 Orthostatic hypotension did not occur in PSP subjects or

58 Orthostatic hypotension did not predict falls after cont

59 tions and can capture clinically significant orthostatic hypotension during activities of daily livin

60 Low incidence of orthostatic hypotension has been reported for silodosin,

61 Instead, patients with PD and orthostatic hypotension have clear evidence for barorefl

62 Orthostatic hypotension in patients with parkinsonism ha

63 Additional options for treatment of orthostatic hypotension include erythropoietin and, surp

64 Orthostatic hypotension is relatively uncommon, may be a

65 In LBD, orthostatic hypotension may be due primarily to involvem

66 Orthostatic hypotension may respond to erythropoietin or

67 Initial orthostatic hypotension occurred in 32.9% (95% CI, 31.2%

68 available concerning the predictive value of orthostatic hypotension on mortality in ambulatory elder

69 Patients with orthostatic hypotension or absent sympathetic skin respo

70 itation on return, no astronauts experienced orthostatic hypotension or intolerance during routine (f

71 No crew member exhibited orthostatic hypotension or presyncopal symptoms during t

72 ve supranuclear palsy if a patient developed orthostatic hypotension or urinary incontinence with the

73 cterised by autonomic failure, manifested as orthostatic hypotension or urogenital dysfunction, with

74 Whereas neurogenic orthostatic hypotension poses risks for falls and can be

75 or autonomic failure in Parkinson disease), orthostatic hypotension reflects sympathetic neurocircul

76 uncomplicated faint, situational syncope, or orthostatic hypotension should receive electrocardiograp

77 apeutic requirements for managing neurogenic orthostatic hypotension that manifests with falls or cog

78 The prevalence of orthostatic hypotension was 6.9% (95% CI, 5.9%-7.8%) in

79 Overall prevalence of orthostatic hypotension was 6.9% and increased with age.

80 t stroke, coronary heart disease and cancer, orthostatic hypotension was a significant independent pr

81 Program's fourth examination (1991 to 1993), orthostatic hypotension was assessed in relation to subs

82 Orthostatic hypotension was defined as a drop in systoli

83 ed mortality rates in those with and without orthostatic hypotension were 56.6 and 38.6 per 1000 pers

84 ay contribute to the increased prevalence of orthostatic hypotension with age.

85 es, head trauma, hypertension in midlife and orthostatic hypotension) and 9 with Level B weaker evide

86 ous events, two of which (hallucinations and orthostatic hypotension) were deemed related to study dr

87 , urinary symptoms, erectile dysfunction and orthostatic hypotension) were noted.

88 In 9 patients without orthostatic hypotension, 6-[(18)F]fluorodopamine positro

89 sed a significant increase in heart rate and orthostatic hypotension, and 20% of the nortriptyline-tr

90 imates of impaired BP stabilization, initial orthostatic hypotension, and orthostatic hypotension are

91 c blood pressure (BP) stabilization, initial orthostatic hypotension, and orthostatic hypotension bas

92 re likely to have mild cognitive impairment, orthostatic hypotension, and RBD at baseline, and at pro

93 ients with PD for mild cognitive impairment, orthostatic hypotension, and RBD even at baseline visits

94 to Earth, including inordinate tachycardia, orthostatic hypotension, and uncommonly, syncope.

95 Orthostatic hypotension, before or in the setting of mor

96 e develop autonomic dysfunction, featured by orthostatic hypotension, constipation, hypohidrosis and

97 and all with Parkinson's disease-associated orthostatic hypotension, have a loss of cardiac sympathe

98 pertensive crises, hypotensive episodes, and orthostatic hypotension, making it the most difficult fo

99 The best cluster solution found was based on orthostatic hypotension, mild cognitive impairment, rapi

100 n, upper gastrointestinal tract dysfunction, orthostatic hypotension, sweating abnormalities, or erec

101 gene encoding alpha-synuclein, also features orthostatic hypotension, sympathetic neurocirculatory fa

102 Orthostatic hypotension, syncope, dyskinesia, hallucinat

103 e symptomatic autonomic failure (symptomatic orthostatic hypotension, urinary incontinence, or both)

104 perechogenicity, olfactory loss, depression, orthostatic hypotension, urinary/erectile dysfunction, P

105 sk factors were identified across 6 domains: orthostatic hypotension, visual impairment, impairment o

106 eral vascular resistance, often resulting in orthostatic hypotension.

107 ents were peripheral oedema, hypotension, or orthostatic hypotension.

108 oreceptor-cardiac reflex function and causes orthostatic hypotension.

109 Midodrine is an alpha1-agonist approved for orthostatic hypotension.

110 m serve to protect against the occurrence of orthostatic hypotension.

111 Five of the LBD cases and all MSA cases had orthostatic hypotension.

112 action can be beneficial in the treatment of orthostatic hypotension.

113 ls, anemia, fatigue, nausea or vomiting, and orthostatic hypotension.

114 tive heart failure, cardiac arrhythmias, and orthostatic hypotension.

115 r other causes, such as vasovagal syncope or orthostatic hypotension.

116 with standing, in the absence of significant orthostatic hypotension.

117 hort over 4 years; of those who died, 52 had orthostatic hypotension.

118 One subject had evidence of orthostatic hypotension.

119 supine hypertension when treating neurogenic orthostatic hypotension; the effectiveness of nocturnal

120 Identification of the gene responsible for orthostatic hypotensive disorder in these families may a

121 Familial orthostatic hypotensive disorder is characterized by lig

122 No orthostatic hypotensive or hypertensive reactions were o

123 Patients with POTS had a higher orthostatic increase in HR than controls (51+/-18 versus

124 phrine was normal supine (203.6+/-112.7) but orthostatic increment of 33.5+/-23.2% was reduced.

125 heat stress augments and cooling attenuates orthostatic-induced decreases in stroke volume (SV) via

126 Chronic orthostatic intolerance (COI) is a debilitating autonomi

127 Chronic orthostatic intolerance (COI) occurs in postural tachyca

128 ed by tilt-table testing on 15 subjects with orthostatic intolerance (OI) and UARS, five normotensive

129 Chronic orthostatic intolerance (OI) is characterized by symptom

130 in an individual with the autonomic disorder orthostatic intolerance (OI).

131 y are likely responsible for the symptoms of orthostatic intolerance across the menstrual cycle in wo

132 are probably responsible for the symptoms of orthostatic intolerance across the menstrual cycle in wo

133 Orthostatic intolerance after bed rest is characterized

134 In a patient with orthostatic intolerance and her relatives, we measured p

135 Chronic orthostatic intolerance associated with postural tachyca

136 s during head-up tilt (HUT) in patients with orthostatic intolerance during daily life, and to identi

137 orthostatic tolerance during cold stress and orthostatic intolerance during heat stress.

138 Patients with idiopathic orthostatic intolerance had lower cardiac vagal barorefl

139 Patients with idiopathic orthostatic intolerance have lower cardiac vagal baroref

140 ure (BP) variability also is associated with orthostatic intolerance in certain patient populations a

141 the heart' is implicated in certain types of orthostatic intolerance in humans.

142 ation therapy are more effective in treating orthostatic intolerance in patients with CFS.

143 lt-table testing may be indicated to confirm orthostatic intolerance in subjects with UARS.

144 HUT fails to reproduce symptoms of orthostatic intolerance in the majority of patients.

145 dia syndrome (POTS), the most common form of orthostatic intolerance in young people, affects approxi

146 Orthostatic intolerance is a syndrome characterized by l

147 Orthostatic intolerance is characterized by postural tac

148 Orthostatic intolerance is common when astronauts return

149 mild syndrome of orthostatic tachycardia or orthostatic intolerance may appear.

150 ia syndrome (POTS) induces disabling chronic orthostatic intolerance notable for an excessive increas

151 repeated neurocardiogenic presyncope (NCS), orthostatic intolerance occurs without persistent sympat

152 Patients diagnosed with idiopathic orthostatic intolerance report symptoms of lightheadedne

153 Young women are more susceptible to orthostatic intolerance than men, though the sex-specifi

154 ental mechanisms associated with post-flight orthostatic intolerance we investigated the interaction

155 ia syndrome (POTS) induces disabling chronic orthostatic intolerance with an excessive increase in he

156 re commonly used in the treatment of chronic orthostatic intolerance with postural tachycardia syndro

157 m onset (hazard ratio 1.67, P < 0.003); (iv) orthostatic intolerance within 1 year of symptom onset (

158 e hypothesized that patients with idiopathic orthostatic intolerance would have impaired cardiac vaga

159 by echocardiogram, weight loss > 10 pounds, orthostatic intolerance, fatigue) in combination were hi

160 uced red blood cell masses, hypovolaemia and orthostatic intolerance, marked by greater cardio-accele

161 Peak work capacity, activity level, orthostatic intolerance, salivary cortisol, and natural

162 (P< .001), primarily due to elevation of the orthostatic intolerance, secretomotor, upper gastrointes

163 Women are more susceptible to orthostatic intolerance.

164 a mechanism responsible for postspaceflight orthostatic intolerance.

165 chanism underlying individual variability in orthostatic intolerance.

166 iciency is linked to tachycardia in familial orthostatic intolerance.

167 that may contribute to, rather than offset, orthostatic intolerance.

168 ts in the treatment of patients with chronic orthostatic intolerance.

169 povolemia alone, potentially contributing to orthostatic intolerance.

170 ributes to the pathophysiologic mechanism of orthostatic intolerance.

171 underlie hyperadrenergic states that lead to orthostatic intolerance.

172 an norepinephrine transporter contributes to orthostatic intolerance.

173 changes that might contribute to postflight orthostatic intolerance.

174 les or stand tests, no astronaut experienced orthostatic intolerance/hypotension during activities of

175 ion between the chronic fatigue syndrome and orthostatic intolerance; however, treatment with the sal

176 Orthostatic intraocular pressure and mean arterial blood

177 We conclude that MHR1/2 acts as a orthostatic ligand-binding site for TRPM2.

178 ing specific interventions for presyncope of orthostatic or vasovagal origin and recommends the use o

179 of treatments for presyncope of vasovagal or orthostatic origin.

180 load during thermal and combined thermal and orthostatic perturbations.

181 e series documented mild ptosis and striking orthostatic reductions in intraocular pressure and mean

182 and forearm vascular resistance (FVR) during orthostatic stress achieved by stepwise increases in low

183 ing leads to a greater decrease in SV during orthostatic stress after bed rest than hypovolemia alone

184 re and the Starling curve was steeper during orthostatic stress after HDTBR than after hypovolemia.

185 ia, astronauts respond normally to simulated orthostatic stress and are able to maintain their arteri

186 cohol consumption elicits hypotension during orthostatic stress because of impairment of vasoconstric

187 y assessed the heart variability response to orthostatic stress during tilt table testing before and

188 Impairment of the response to orthostatic stress may be involved.

189 The effect of orthostatic stress on dynamic cerebral autoregulation (C

190 n against cardiovascular collapse induced by orthostatic stress or hemorrhage.

191 Patients underwent a progressive orthostatic stress test, which continued to pre-syncope

192 Because orthostatic stress varies from moment to moment and drug

193 The symptoms vary with orthostatic stress, and subtle symptoms such as tirednes

194 easurements were made during supine rest and orthostatic stress, as simulated on Earth and in space b

195 the maintenance of arterial pressure during orthostatic stress.

196 ascular regulation have been observed during orthostatic stress.

197 ute to impaired AVP secretion in response to orthostatic stress.

198 t in the regulation of blood pressure during orthostatic stress.

199 activity and arterial blood pressure during orthostatic stress.

200 pathetic increases that occur in response to orthostatic stress.

201 and impairs sympathetic neural responses to orthostatic stress.

202 d hypotension (NMH) in response to prolonged orthostatic stress.

203 ility to increase vascular resistance during orthostatic stress.

204 mpairment in the vasoconstrictor response to orthostatic stress.

205 re and vasoconstriction in POTS women during orthostatic stress.

206 to investigate the frequency and pattern of orthostatic symptoms during head-up tilt (HUT) in patien

207 Only 25% of the patients reported orthostatic symptoms during HUT and 75% were asymptomati

208 and to identify the relationship between the orthostatic symptoms during HUT and autonomic parameters

209 We also investigated orthostatic symptoms during HUT.

210 Typical orthostatic symptoms such as orthostatic dizziness and b

211 yndrome (POTS) with exaggerated tachycardia, orthostatic symptoms, and "pooling" (which comprises acr

212 syndrome, sleep apnoea, urinary dysfunction, orthostatic symptoms, depression, anxiety, or hyperechog

213 iated with elevated catecholamine levels and orthostatic symptoms.

214 lected autonomic data from 464 patients with orthostatic symptoms.

215 t and included headache, chest pressure, and orthostatic symptoms.

216 Polygraphic recordings revealed an orthostatic synchronic tremor with 17.5-Hz frequency.

217 Idiopathic orthostatic tachycardia (IOT) is characterized by an inc

218 ow dose in standing heart rate (P<0.001) and orthostatic tachycardia (P<0.001), the improvement in sy

219 New entities, such as postural orthostatic tachycardia and cerebral vasoconstrictive sy

220 yndrome (POTS) is characterized by excessive orthostatic tachycardia and significant functional disab

221 of baroreflex afferents, a mild syndrome of orthostatic tachycardia or orthostatic intolerance may a

222 ced blood volume contributes to the postural orthostatic tachycardia syndrome (POTS) and that exercis

223 Patients with the postural orthostatic tachycardia syndrome (POTS) are primarily pr

224 Women with the postural orthostatic tachycardia syndrome (POTS) report fluctuati

225 omponent of the pathogenesis of the postural orthostatic tachycardia syndrome (POTS), similar to phys

226 Postural orthostatic tachycardia syndrome (POTS), the most common

227 Fibroblasts from a patient with postural orthostatic tachycardia syndrome (POTS), who presented w

228 ion/syncope, tachycardia (including postural orthostatic tachycardia syndrome), and malaise/fatigue (

229 ropriate sinus tachycardia and from postural orthostatic tachycardia syndrome, with which overlap may

230 posture and may contribute to the subsequent orthostatic tachycardia that is the hallmark of this dis

231 Activity level, exercise tolerance, and orthostatic testing could not distinguish patients with

232 iorated the heat stress-induced reduction in orthostatic tolerance (1110 +/- 69 CSI, P < 0.001).

233 negative pressure test to determine level of orthostatic tolerance (cumulative stress index, CSI), wo

234 Orthostatic tolerance (expressed in cumulative stress in

235 nces adrenergic responses in women with high orthostatic tolerance (HT).

236 neous adrenergic responses in women with low orthostatic tolerance (LT), whereas progesterone enhance

237 We examined two novel hypotheses: (1) that orthostatic tolerance (OT) would be prolonged when hyper

238 uated the impact of prolonged spaceflight on orthostatic tolerance and BP profiles in astronauts.

239 Dehydration is known to decrease orthostatic tolerance and cause tachycardia, but little

240 Astronauts returning to Earth have reduced orthostatic tolerance and exercise capacity.

241 Phenylephrine, but not esmolol, improves orthostatic tolerance and hemodynamics in POTS.

242 Phenylephrine improved orthostatic tolerance and normalized hemodynamics and in

243 mpathetic tone in patients with NMS improves orthostatic tolerance and raises the possibility that th

244 Whole-body heat stress alone reduced orthostatic tolerance by approximately 80% compared to n

245 ng, but no studies have evaluated postflight orthostatic tolerance during activities of daily living,

246 mechanism may contribute to improvements in orthostatic tolerance during cold stress and orthostatic

247 dicate that midodrine significantly improves orthostatic tolerance during head-up tilt in patients wi

248 rial blood pressure in an effort to preserve orthostatic tolerance during heat stress.

249 body mass index 22 +/- 1 kg m(-2)) or a high orthostatic tolerance group (HT, n = 7, 22 +/- 1 years o

250 and nonneural tissue, on blood pressure and orthostatic tolerance in 19 patients with severe NOH (8

251 00+/-6 mm Hg) for several hours and improved orthostatic tolerance in all patients.

252 soconstrictor capability is a contributor to orthostatic tolerance in humans.

253 whether prophylactic water drinking improves orthostatic tolerance in normal healthy adults.

254 L-DOPS increases blood pressure and improves orthostatic tolerance in patients with NOH.

255 rough an impedance threshold device (ITD) on orthostatic tolerance in patients with postural tachycar

256 cycle alter sympathetic neural activity and orthostatic tolerance in POTS women.

257 nderlying mechanism responsible for impaired orthostatic tolerance in the heat-stressed human.

258 ower stroke volume contribute to compromised orthostatic tolerance in women; this inability to vasoco

259 mechanisms contribute to sex differences in orthostatic tolerance in young humans.

260 he hypothesis that individual variability in orthostatic tolerance is dependent on the degree of neur

261 Esmolol did not improve orthostatic tolerance or hemodynamics.

262 ensated Fontan subjects demonstrate superior orthostatic tolerance resulting from decreased compartme

263 ardia syndrome (POTS) report fluctuations in orthostatic tolerance throughout the menstrual cycle.

264 Whole-body heat stress reduces orthostatic tolerance via a yet to be identified mechani

265 jects (age, 40 +/- 10 years: mean +/- S.D.), orthostatic tolerance was assessed using graded lower-bo

266 Orthostatic tolerance was determined by progressive lowe

267 turning to earth usually demonstrate reduced orthostatic tolerance when assessed on a tilt table or q

268 tal conditions have the capacity to modulate orthostatic tolerance, where heat stress decreases and c

269 e sensitive to E2 exposure in women with low orthostatic tolerance.

270 ibute to sex differences in hypertension and orthostatic tolerance.

271 oxygenase pathway in women with high and low orthostatic tolerance.

272 attenuates heat stress-induced reductions in orthostatic tolerance.

273 heat stress decreases and cooling increases orthostatic tolerance.

274 d heart rate responses to orthostasis in low orthostatic tolerant women, which is likely to be a comp

275 Patients with primary orthostatic tremor (OT) experience a disabling sense of

276 Orthostatic tremor (OT) is a high-frequency (13-18 Hz) l

277 s, 86.8% of patients presented with isolated orthostatic tremor and 13.2% had additional neurological

278 inical and electrophysiological diagnosis of orthostatic tremor and a minimum follow-up of 5 years is

279 Although the essential clinical features of orthostatic tremor are well established, little is known

280 There was no change in orthostatic tremor frequency over time.

281 Orthostatic tremor has an unknown pathophysiologic mecha

282 Orthostatic tremor is a progressive disorder with increa

283 Orthostatic tremor is a rare condition characterised by

284 Primary orthostatic tremor is characterized by unsteadiness and

285 p, seven patients who initially had isolated orthostatic tremor later developed further neurological

286 istic, action tremor, re-emergent tremor and orthostatic tremor may occur in Parkinson disease.

287 postural muscle EMG signals in five primary orthostatic tremor patients and in two normal controls t

288 In most cases, orthostatic tremor represents an isolated syndrome.

289 otal 79.4% of patients reported worsening of orthostatic tremor symptoms.

290 olated tongue tremor, Wilson's disease, slow orthostatic tremor, peripheral trauma-induced tremor, ta

291 The condition known as primary orthostatic tremor, which is not too well known to many

292 are due to the primary pathology of primary orthostatic tremor.

293 largest multicentre cohort of patients with orthostatic tremor.

294 Rest, Holmes' ('rubral') and primary orthostatic tremors were not encountered.

295 limb blood flow ("high flow") and defective orthostatic vasoconstriction or decreased limb blood flo

296 We studied hemodynamic changes leading to orthostatic vasovagal presyncope to determine whether ch

297 oregulation contributes to the occurrence of orthostatic vasovagal syncope.

298 rterial pressure reductions in patients with orthostatic vasovagal syncope.

299 story and physical examination that includes orthostatic vital signs measured in both recumbent and v

300 mistry, hematology, coagulation, urinalysis, orthostatic vital signs, WSF, or 12-lead ECG parameters.

301 ose and postdose safety assessments included orthostatic vital signs; 6-lead continuous telemetry mon