ライフサイエンスコーパス: osmolality

1 siologic corticomedullary gradient of tissue osmolality.

2 nt with increases in fluid intake and plasma osmolality.

3 hysiological levels and inhibited by reduced osmolality.

4 ns showed reasonable agreement with measured osmolality.

5 a decreased urine volume and increased urine osmolality.

6 tion of chromatin, with increasing lubricant osmolality.

7 egardless of hemodynamic stability and serum osmolality.

8 th acute and chronic increases of body fluid osmolality.

9 of collecting duct epithelial cells in high osmolality.

10 ter is dependent on achieving a target serum osmolality.

11 om slower diffusion of TCs under high growth osmolality.

12 smolality, and correct serum [Na+] and serum osmolality.

13 dewetting) resulting in increased tear film osmolality.

14 tion or by the diffusion of free TCs at high osmolality.

15 nguishable from +/+ in BP, urine volume, and osmolality.

16 ead, due to impaired growth at physiological osmolality.

17 entration and not to increased extracellular osmolality.

18 ers and all solutes increase with increasing osmolality.

19 correlated inversely with changes in plasma osmolality.

20 ) and biopolymers (crowding) with increasing osmolality.

21 consumption, even prior to changes in blood osmolality.

22 ignificantly affected by contrast volume and osmolality.

23 ake and urine volume, alongside higher urine osmolality.

24 coiled-coil domain respond similarly to the osmolality.

25 ProP activity is a sigmoidal function of the osmolality.

26 h is necessary for achieving the homeostatic osmolality.

27 (WT) mice while maintaining a similar plasma osmolality.

28 ia with an inappropriate decrease in urinary osmolality.

29 vaded more when placed in media of increased osmolality.

30 genes can be modulated by the extracellular osmolality.

31 y a hormone signal of nutrient levels and by osmolality.

32 lity at a faster rate than changes in ocular osmolality.

33 -/-)), which display reduced renal medullary osmolality.

34 ater uptake and resumption of growth at high osmolality.

35 minimal medium over a wide range of external osmolalities (0.03 to 1.8 osmol).

36 -12 grown over a wide range of high external osmolalities (1.02-2.17 Osm) in MOPS-buffered minimal me

37 us infusion of HYPER saline increased plasma osmolality (294 +/- 3 to 316 +/- 5 mOsm kg(-1) H2O, P </

38 ite better renal free water excretion (urine osmolality 343+/-101 mOsm/kg versus 475+/-136; P<0.001).

39 +/+) mice (1.6 ml/day) and had reduced urine osmolality (400 vs. 1800 mosmol).

40 by which they are accumulated; 4) sensors of osmolality; 5) the signaling pathways involved; and 6) m

41 of the equilibrium constant on the solution osmolality, 60 +/- 13 waters are acquired in the complex

42 plasma renin concentration, urine volume and osmolality, ability to concentrate and dilute urine, and

43 metabolites are largely responsible for leaf osmolality above a baseline level (approximately 300 mm)

44 Further, we found that HSD elevated skin osmolality above plasma levels.

45 However, the osmolality adjusted sum, U-As(IMM), of urinary inorganic

46 rapeutic concentrations in the kidney, urine osmolality after administration of 1-deamino-8-D-arginin

47 g nutritional status to the control of blood osmolality, although the mechanism of this systemic cros

48 des for water rewards as a function of blood osmolality (an objective measure of how much water the s

49 ndance is tightly regulated along a range of osmolalities and that AQP5 reduction by extracellular hy

50 Under basal conditions, plasma and urine osmolalities and urine volumes were similar between CD-K

51 During brief periods of arousal, serum osmolality and antidiuretic hormone levels are restored,

52 ced similar antidiuresis and increased urine osmolality and aquaporin-2 abundance.

53 gnificant increase in water retention, urine osmolality and aquaporin-2 expression and phosphorylatio

54 There was a strong correlation between serum osmolality and attenuation of stroke-associated increase

55 ween the regulation of blood volume/pressure/osmolality and blood glucose.

56 ement and differential bias between measured osmolality and calculated osmolarity.

57 (MNCs) of the supra optic nucleus can sense osmolality and control the synthesis and secretion of va

58 ntrations were higher in samples with raised osmolality and copeptin (surrogate marker for AVP).

59 During HYPER, plasma osmolality and copeptin increased (P < 0.05) and remaine

60 ukaryotes, bacteria undergo large changes in osmolality and cytoplasmic pH.

61 e correlation (r = 0.7326) between lubricant osmolality and cytotoxicity in monolayer VECs, and cell

62 ls, water and sodium reabsorption, and urine osmolality and decreased urine output (P </= 0.04, excep

63 Differences in responses to osmolality and direct depolarization in vitro indicate t

64 duction strongly correlated with lower urine osmolality and elevated water intake.

65 tectant (efficient at increasing cytoplasmic osmolality and growth rate) and a compatible solute (wit

66 P levels, free water reabsorption, and urine osmolality and increased urine output (P </= 0.03 except

67 ls, water and sodium reabsorption, and urine osmolality and increased urine output, while raxibacumab

68 ls and the correlation between osmole gap or osmolality and mannitol serum concentrations in ten NNIC

69 mpared with control rats at comparable serum osmolality and plasma vasopressin concentrations.

70 n and calcium content, while increasing milk osmolality and protein concentrations.

71 re, we analyzed serial measurements of serum osmolality and serum sodium, plasma arginine vasopressin

72 urinary pH (P < 0.001) and decreased urinary osmolality and urea concentration (P < 0.001) in SD rats

73 Hydration status (plasma osmolality and urine specific gravity) and body composit

74 than resting indices regardless of contrast osmolality and volume (P<0.001 for all groups).

75 which in turn influence the osmotic (plasma osmolality) and blood volume-dependent compensatory thre

76 plasmic osmolalities greatly exceed observed osmolalities, and the efficiency of GB as an osmolality

77 tter with mannitol serum concentrations than osmolality, and although it cannot predict a specific ma

78 augment free water clearance, decrease urine osmolality, and correct serum [Na+] and serum osmolality

79 uding standardization by urinary creatinine, osmolality, and flow rates, and inclusion of these metri

80 rbs that load passively, have low K(p), high osmolality, and high concentrations of transport sugars

81 bserved marked antidiuresis, increased urine osmolality, and increased solute-free water reabsorption

82 The reference standard was serum osmolality, and index tests included USG, urine color, u

83 ively load sucrose alone have high K(p), low osmolality, and low concentrations of sugars and total p

84 The changes in milk calcium content, milk osmolality, and milk protein concentration were mitigate

85 ificantly higher symptom scores, higher tear osmolality, and shorter TBUT than healthy controls.

86 o significant differences in urinary volume, osmolality, and sodium content after the three infusions

87 genic site O when exposed to extremes of pH, osmolality, and temperature.

88 Urine volume, urine osmolality, and urinary excretion of sodium and creatini

89 , blood pressure, serum and urine sodium and osmolality, and urine output.

90 that contributions of individual solutes to osmolality are additive and using in vitro osmotic data

91 Plasma and urinary osmolality are decreased in FP KOs that exhibit mild pol

92 n a liquid environment whose composition and osmolality are maintained within tight limits.

93 y expressed TRPM8 was activated by increased osmolality around physiological levels and inhibited by

94 Analysis of osmolality as a function of solute and DNA concentration

95 greater urine flow rate and decreased urine osmolality as compared with control rats at comparable s

96 flow rates and decreased urine and medullary osmolality as compared with CTL and HT+T rats at compara

97 At constant external osmolality, aspiration increases the surface area of the

98 ally accepted that dialysis may lower plasma osmolality at a faster rate than changes in ocular osmol

99 normalities, mutant mice exhibited low urine osmolality at baseline and after water restriction and a

100 are confronted with changes in extracellular osmolality at various sites, including the aqueous layer

101 .11; 95% CI, 0.01 to 0.20; P=0.03) and urine osmolality (beta=0.08; 95% CI, 0.05 to 0.10; P<0.001).

102 Changes in body mass, urine osmolality, body temperature, and thirst were monitored.

103 osmolalities, and the efficiency of GB as an osmolality booster decreases as the amount of cytoplasmi

104 ns that increased linearly with rising serum osmolality but had abnormally low osmotic thresholds (ty

105 eurons respond to increases in extracellular osmolality but the mechanism responsible for excitation

106 ProP activity at high osmolality, but not the osmolality, yielding half-maxima

107 rity, which is an indirect estimate of serum osmolality, but which serum osmolarity equations best pr

108 Bacteria respond to increasing medium osmolality by accumulating organic solutes that are comp

109 d urine output by 3-5-fold and reduced urine osmolality by approximately 2-fold compared to vehicle c

110 The spheroplasts can adjust their internal osmolality by increasing their volumes more than three t

111 more, culture conditions like temperature or osmolality can be simultaneously monitored by SAW.

112 ages, parasites are able to survive dramatic osmolality changes between its vector, fresh water, and

113 ed whole-plant hydraulic conductance (K(p)), osmolality, concentrations of polar metabolites, and key

114 f cFFR between patients receiving low or iso-osmolality contrast (n=574 versus 189) and low or high c

115 s and with intravenous administration of low-osmolality contrast material in 112.

116 Intravenous administration of low-osmolality contrast material is significantly associated

117 ntrast medium iopamidol with that of the iso-osmolality contrast medium iodixanol in high-risk patien

118 s exist of the renal tolerability of the low-osmolality contrast medium iopamidol with that of the is

119 ticosteroid premedication regimen before low-osmolality contrast-enhanced CT for a prior allergic-lik

120 e, water will readily flow inside the higher osmolality cytoplasm.

121 expression by hyperosmolality in a time- and osmolality-dependent fashion.

122 ch functions as the osmosensing core through osmolality-dependent helical stabilization.

123 This osmolality-dependent relocation to the division apparatu

124 However, contrast volume and osmolality do affect the sensitivity and specificity of

125 Further increases in osmolality drove formation of two chemically distinct da

126 reduced urine flow and two-fold higher urine osmolality during the first 12 hours of treatment compar

127 The results elucidate the osmolality dynamics involved in the enzymatic hydrolysis

128 An elevation in plasma osmolality elicits a complex neurohumoral response, incl

129 Here we show that small increases in osmolality excite isolated mouse dorsal root ganglion (D

130 on between copeptin concentrations and serum osmolality existed in 68 healthy controls, with a mean o

131 (symptom questionnaire) and objective (tear osmolality, fluorescein tear break-up time [TBUT]) measu

132 evious extrapolations and, combined with new osmolalities from bathyal and abyssal fishes, predict is

133 We find that raising osmolality from 300 to 500 mosmol/kg by adding NaCl acti

134 terase (GPC-PDE) activity and that elevating osmolality from 300 to 500 mosmol/kg by adding NaCl or u

135 mbedded into a gradient of increasing tissue osmolality from the cortex to the medulla, which may alt

136 Direct measurement of tissue osmolality further revealed lymphoid tissues to be hyper

137 In the outer medulla, the osmolality gradient arises principally from vigorous act

138 fficient to form anion channels activated by osmolality gradients.

139 tle cytoplasmic water, predicted cytoplasmic osmolalities greatly exceed observed osmolalities, and t

140 under the curve of cFFR in the low- and iso-osmolality groups (0.938 versus 0.957; P=0.40) and in th

141 rall accuracy of cFFR for the low versus iso-osmolality groups were 73%, 93%, and 85% versus 87%, 90%

142 had impending or current dehydration (serum osmolality >/=295 mmol/kg).

143 f NU-AGE participants were dehydrated (serum osmolality >300 mOsm/kg).

144 Osmolality had the lowest correlation with mannitol conc

145 Changes in extracellular osmolality have been shown to alter gene expression patt

146 ecific gravity (USG), urine color, and urine osmolality have been widely advocated for screening for

147 Although USG, urine color, and urinary osmolality have been widely advocated for screening for

148 al growth being slower in protein-rich, high-osmolality hemolymphs, highlighting a novel "bottom-up"

149 st dietary protein on host hemolymph (blood) osmolality (i.e., its concentration of solutes), with ba

150 ich physiological or pathological changes in osmolality impact chondrocyte function remain unclear.

151 Notably, basal urine osmolalities in both wild-type and UT-A1(+/+)/UT-A3(-/-)

152 ially available lubricants across a range of osmolalities in human monolayer vaginal epithelial cell

153 17-AAG increased urine osmolality in AQP2(T126M/-) mice by >300 mosmol but had

154 s produced a partial increase in the urinary osmolality in homozygous individuals and decreased their

155 lso increased urine output and reduced urine osmolality in mice given free access to water.

156 sed increased urine output and reduced urine osmolality in mice that was associated with decreased ex

157 The increase in urine osmolality in response to water deprivation or vasopress

158 erum osmolarity equations best predict serum osmolality in the elderly is unclear.

159 ignificantly decreased, as was the medullary osmolality in the GD rats versus control rats.

160 UTB(inh)-14 did not reduce urine osmolality in UT-B knockout mice.

161 PLP-null myelin lamellae and fluctuations in osmolality in vivo might underlie slowing of conduction

162 However, the urine osmolality increase was greater within the physiological

163 Urinary osmolality increased with increasing BMI.

164 ction of rats or mice led to increased urine osmolality, increased Sgk1 expression, increased express

165 feration and migration or when intracellular osmolality increases due to transepithelial transport.

166 High osmolality increases phosphorylation at T135 in HEK293 c

167 As osmolality increases, we observe that the amount of cyto

168 e distribution of D(peri) broadens as growth osmolality increases.

169 pling together with measurements of leaf sap osmolality indicate a passive symplasmic loading type.

170 outflow with concomitant reduction of urine osmolality, indicating a purely aquaretic effect associa

171 Hyper-osmolality induced via 2% hypertonic saline ingestion si

172 nificantly decreased, whereas sustained hypo-osmolality induced via d-d-arginine VP and liquid diet i

173 Increased blood osmolality induces osmotic thirst that drives animals to

174 Bacterial responses to decreasing osmolality involve mechanosensitive channels.

175 Intravenous low-osmolality iodinated contrast material had a significant

176 Intravenous low-osmolality iodinated contrast material is a nephrotoxic

177 derwent contrast-enhanced CT with either iso-osmolality iodixanol (n = 61) or low-osmolality iopromid

178 her iso-osmolality iodixanol (n = 61) or low-osmolality iopromide (n = 56).

179 attenuated with hypertonic saline when serum osmolality is >350 mOsm/L without adverse effect on mort

180 Interstitial osmolality is a key homeostatic variable that varies dep

181 Because hyper-osmolality is a potent stimulus for VP and OT release, t

182 s relatively large, we find that cytoplasmic osmolality is adequately predicted by assuming that cont

183 Serum osmolality is an accurate indicator of hydration status

184 ity of the conformational change to solution osmolality is consistent with a structural model predict

185 Plasma volume is expanded and plasma osmolality is decreased, yet vasopressin secretion in pr

186 ease in glucose, electrolytes, and resultant osmolality is desired.

187 secretory glands, sites where extracellular osmolality is known to fluctuate.

188 Ambient tonicity (effective osmolality) is the prominent signal for TonEBP in a bidi

189 g the activation of SLC26A7 activity by high osmolality, it is proposed that SLC26A7 may play an impo

190 poor nutrient quality or from higher growth osmolality, k(trl) decreases significantly.

191 yponatremia (<125 mmol/L) and lower baseline osmolality levels increased the likelihood of response t

192 d low-dosage and high-dosage gadodiamide and osmolality-matched saline controls.

193 However, contrast media volume and osmolality may affect the degree of hyperemia and theref

194 ith obesity, and that urinary creatinine and osmolality may be colliders on the causal pathway from a

195 s of repressor-DNA complexes with increasing osmolality may contribute to the ability of Escherichia

196 kage, as well as the change in extracellular osmolality, may have a significant impact on chondrocyte

197 Osmolality measurements documented the non-idealities of

198 , and month 6, and values were corrected for osmolality (mOsm).

199 classical homeostatic, interosensory plasma osmolality negative feedback as well as by novel, extero

200 profiles, spleen function biomarkers, urine osmolality, neurodevelopment, transcranial Doppler ultra

201 ession analysis showed that neither contrast osmolality nor volume affected the overall accuracy of c

202 Preliminary extrapolation of osmolalities of predicted isosmotic state at 8,000-8,500

203 ave a TMAO content of 386 +/- 18 mmol/kg and osmolality of 991 +/- 22 mOsmol/kg.

204 the VR agonist dDAVP did not increase urine osmolality of AC6-deficient mice to the levels of wild-t

205 nditions found within the host, including an osmolality of approximately 290 mosmol kg(-1).

206 c saline therapy maintained to achieve serum osmolality of approximately 350 mOsm/L is beneficial for

207 brain plays a pivotal role in regulating the osmolality of body fluids.

208 on through PDMS and associated shifts in the osmolality of culture media was significant and prevente

209 ic players in the ageing process, and affect osmolality of growth media in stationary phase cultures.

210 on, real-time, non-destructive monitoring of osmolality of infant milks, including breast milk, durin

211 The osmolality of plasma was measured by using freezing poin

212 ls and quantified the response to changes in osmolality of the bathing solution.

213 However, the osmolality of the circulating blood decreases with the u

214 y cause water excretion, which increases the osmolality of the circulating blood, potentially improvi

215 identify genes affected by the environmental osmolality of the culture medium.

216 s the same maximal level irrespective of the osmolality of the media.

217 privation, a condition known to increase the osmolality of the medulla.

218 e binding site decreases with the increasing osmolality of the solution, resulting in acquisition of

219 dextrose, desmopressin does not increase the osmolality of the urine in -/- mice (624 +/- 19 to 656 +

220 The effect of changes in osmolality on nuclear morphology (p < 0.01) and chromati

221 ntrations were higher in samples with raised osmolality or copeptin (a surrogate marker for AVP).

222 es C due to nutrient limitation, high growth osmolality, or both.

223 plasma AVP concentration ([AVP]P) vs. urine osmolality (OsmU) were fitted to a sigmoidal curve, and

224 Total water intake (P = 0.002), urine osmolality (P < 0.001), and hypohydration prevalence (P

225 and polyuria (P < 0.04), with a lower urine osmolality (P < 0.003) as compared to Nhe3+/+ mice.

226 8%) had higher glucose (P < 0.001) and serum osmolality (P < 0.01).

227 njection (P = 0.03), and increased tear film osmolality (P = 0.05).

228 However, only plasma osmolality (P(osm)) showed statistical promise for use i

229 vity of a hog1 null mutant in which the high osmolality pathway is disrupted.

230 variety of tear film (e.g., interferometry, osmolality, phenol red thread, meibography, fluorescein,

231 ese results with ongoing behavior and plasma osmolality points to the existence of brain networks tha

232 a sodium (WD(5)), the substitution of plasma osmolality (Posm) for sodium (WD(6)), and actual Posm (W

233 ividuals classified as DE have higher plasma osmolality (Posm), indicating suboptimal hydration, comp

234 rap regression provides a unique insight for osmolality prediction equation performance from a very l

235 mperature shift, serum starvation, increased osmolality, reactive oxygen intermediates, and increased

236 mising equations were examined against serum osmolality (reference standard).

237 Serum osmolality, regional brain water content, blood-brain ba

238 mouse corneal preparation demonstrated that osmolality regulated the electrical activity of TRPM8-ex

239 iverse functions ranging from nociception to osmolality regulation.

240 An acute increase in serum osmolality reinstates water-seeking behavior, demonstrat

241 and urine flow and a reduced maximal urinary osmolality relative to wild-type controls.

242 urine during 24-h water restriction, urinary osmolality remained significantly lower than in WT mice,

243 After recovery, and if the external osmolality remains high, cells have been shown to grow m

244 alts and sugars to modulate conductivity and osmolality, respectively.

245 ous work established that plasma [Na(+)] and osmolality rise in proportion with salt intake and thus

246 unctional copy of an osmoresponsive element, osmolality/salinity-responsive enhancer 1 (OSRE1).

247 armacokinetics, did not affect urine output, osmolality, salt excretion, or acid-base balance.

248 notype is the consequence of decreased urine osmolality secondary to renal vasopressin resistance.

249 ulping-induced oropharyngeal stimuli and gut osmolality sensing.

250 Recently, an osmolality-sensing ion channel called OSCA1 was discover

251 nally, we identify a hormone receptor and an osmolality-sensitive ion channel that underlie this regu

252 , solute and urea excretion, serum and urine osmolality, serum creatinine, 24-h creatinine clearance,

253 Evaporation-mediated osmolality shifts through PDMS membranes with varying th

254 oped that greatly suppresses evaporation and osmolality shifts, yet possesses thinness and the flexib

255 0-9 m2/s, accounts for these evaporation and osmolality shifts.

256 ut there was a significant increase of urine osmolality, suggesting that DI may be caused by a defect

257 65) in WT mice elicited an increase in urine osmolality, suggesting that LXRbeta is a key receptor in

258 serine-256 and serine-269), and lower urine osmolality than wild-type mice.

259 Reducing osmolality to 150 mosmol kg(-1), increased lambda to 1.8

260 produced a physiological increase in plasma osmolality to 299 +/- 1 mosmol (kg water)(-1), elicited

261 An increase in osmolality to 550 milliosmoles per kg of water (mosmol/k

262 nes are activated during increases in plasma osmolality to elicit sympathoexcitation.

263 was accelerated by a return of extracellular osmolality to isosmotic levels.

264 unctionally adapt to changes of interstitial osmolality/tonicity.

265 Bilateral reduction in osmolality transiently increased short-circuit current (

266 Low [Na(+)], rather than low osmolality, triggered these effects.

267 copeptin concentrations independent of serum osmolality (type A); 14% had copeptin concentrations tha

268 ormal copeptin concentrations independent of osmolality (type C), and 12% had suppressed copeptin con

269 essed copeptin concentrations independent of osmolality (type D).

270 opeptin concentrations with increasing serum osmolality (type E or "barostat reset").

271 on with depth results in increasing internal osmolality (typically 350 mOsmol/kg in shallow species c

272 ess biomarkers excreted in urine and urinary osmolality (Uosm).

273 At moderate growth osmolalities (up to 1 Osm), we conclude that GB is an ef

274 index tests included USG, urine color, urine osmolality, urine cloudiness, additional dipstick measur

275 output and fluid intake, and increases urine osmolality, urine sodium concentration, and plasma AVP l

276 further differentiated on the basis of urine osmolality, urine sodium level, and volume status.

277 ssure liquid chromatography, pH measurement, osmolality, visual inspection, and sterility, as require

278 The relationship between condensation and osmolality was accurately modeled by a polymer gel model

279 Serum sodium was measured, serum osmolality was calculated, and echocardiograms and chest

280 Serum osmolality was determined at the end of the experiment i

281 Urine osmolality was determined with the use of freezing-point

282 pacity: Urine flow rate was higher and urine osmolality was lower than control rats despite an increa

283 Serum osmolality was measured by using freezing point depressi

284 rats injected with lipopolysaccharide, urine osmolality was reduced by ~40%, along with medullary ind

285 In states of elevated osmolality, water availability rapidly decreased VPpp ne

286 Nonetheless, urinary osmolalities were similar in mPges1(+/+) and mPges1(-/-)

287 olic cages and their water balance and urine osmolality were examined.

288 atio were observed when either creatinine or osmolality were used to standardize or as covariates.

289 tions appeared optimal for the prediction of osmolality when its direct measurement was not practical

290 fferent equations used for predicting plasma osmolality when its direct measurement was not practical

291 ProP attains the same activity at the same osmolality when the medium outside cells or proteoliposo

292 At very high growth osmolalities where cells contain little cytoplasmic wate

293 ur over a very narrow range of physiological osmolalities, which suggests that chondrocytes likely ex

294 impairment in their water balance and urine osmolality, which correlates with the downregulation of

295 e association between water intake and urine osmolality, which is a hydration biomarker, varied by we

296 The hydrolysis of lactose affects osmolality, which is an important property of infant mil

297 We assessed the agreement of measured serum osmolality with calculated serum osmolarity equations in

298 agreement and the capacity to predict serum osmolality within 2% in >80% of participants, regardless

299 the hypothesis that the unique extracellular osmolality within the renal medulla modulates a specific

300 roP activity at high osmolality, but not the osmolality, yielding half-maximal activity (Pi(1/2)/RT),