ライフサイエンスコーパス: osmotically

1 periplasm, from which it can be removed hypo-osmotically.

2 The system was shown to be both osmotically activated and cryoactivated.

3 DNAs encoding the vanilloid receptor-related osmotically activated channel (VR-OAC) from the rat, mou

4 previously named vanilloid receptor-related osmotically activated channel (VR-OAC), functions in viv

5 Dialysis with phalloidin also prevented hypo-osmotically activated Cl- currents.

6 channel, vanilloid subfamily (TRPV4), is an osmotically activated ion channel that is expressed in c

7 Thus, in addition to defining a novel osmotically activated signal transduction pathway in B c

8 he expression of IEGs and vasopressin in the osmotically activated SON in vivo.

9 arance would increase after inhalation of an osmotically active agent that would increase the volume

10 is observed in the presence of a variety of osmotically active compounds indicating that Em protein

11 The dynamic distribution of these osmotically active compounds is a handy tool for regulat

12 on minimal media with low concentrations of osmotically active compounds.

13 lity (Boyle van't Hoff relationship) with an osmotically active intracellular water fraction of 61%.

14 hanges are aided by the concerted release of osmotically active ions, most notably K(+) and Cl(-).

15 de that oxalate acts via (1) accumulation of osmotically active molecules to induce stomatal opening

16 le, a carbon and energy storage compound, an osmotically active solute, and fuel for many anabolic re

17 h transported L-alanine via system B into an osmotically active space energized by secondary active t

18 ake of L-tryptophan is substantially into an osmotically active space.

19 mine if plants can up-regulate the efflux of osmotically active substances into embolized vessels and

20 ed CSCs using a CD133 peptide attached to an osmotically active vitamin B(6)-coupled polydixylitol ve

21 d that reovirus-induced lysis of RBCs occurs osmotically, after formation of small size-selective les

22 solutions included control Tyrode's (1T) and osmotically altered Tyrode's (2.6T, 0.9T, and 0.6T) solu

23 ICAHM osmotically alters endothelial cells and tight junction

24 nts at the apical, mid, and basal regions of osmotically and electrically stimulated cells.

25 TonEBP/OREBP contain a TAD that is regulated osmotically, apparently by tonicity-dependent phosphoryl

26 diverse sample of pregnant women in the U.S. Osmotically assisted reverse osmosis (OARO) has shown gr

27 A novel adaptation of osmotically assisted reverse osmosis (OARO) is then simu

28 ed from 4.84-22.3 kWh(e)/m(3), assuming that osmotically assisted reverse osmosis is used to regenera

29 ransmembrane movements of cations are always osmotically balanced, regardless of the stoichiometry of

30 is phenotype could be repressed by growth on osmotically buffered medium at low temperature.

31 , but IPSCs, evoked by local stimulation, or osmotically by hypertonic sucrose application, were dimi

32 The LSL-mediated hemolysis was protected osmotically by polyethylene glycol 4000 and maltohexaose

33 Hyaluronan has the greater effect, acting osmotically by way of a concentration polarization bound

34 HeLa cells and U2-OS osteosarcoma cells were osmotically challenged with 100-200 mm sorbitol, and the

35 The fixed stromal charge of bovine corneas, osmotically clamped at physiological hydration, was alte

36 to compare the lattice spacing of dissected, osmotically compressed skinned fibers to native muscle f

37 interesting possibility of dimerization when osmotically compressed to high densities while undergoin

38 med additional experiments on skinned strips osmotically compressed to the intact lattice spacing as

39 are platelets, produced lithographically, is osmotically concentrated in a flat plane to raise the pa

40 First we use a fluorescence assay to track osmotically controlled membrane deformation in single co

41 to the less-dense cholesteric phase through osmotically controlled swelling shows the loss of this b

42 The size of these tubes is osmotically controlled using dialysis, which makes them

43 accompanied by parallel efflux of Cl(-) and osmotically coupled water.

44 red giant unilamellar vesicles (GUVs) can be osmotically deflated to reduced volumes as low as 0.1, s

45 Osmotically dehydrated pork meat (Longissimus dorsi), in

46 er resulted in a significant increase in the osmotically directed net fluid secretion rate across mon

47 Inhaled hypertonic saline osmotically draws water onto airway surfaces, improves m

48 Enhanced movement of cations may osmotically drive water entry, resulting in balloon dege

49 vide additional support for the concept that osmotically driven and agonist-stimulated water movement

50 Potassium flux causes osmotically driven changes in guard cell volume that reg

51 Although these movements are governed by osmotically driven changes in guard cell volume, the rol

52 these amphiphiles grew spontaneously through osmotically driven competition between vesicles, and fur

53 The process of osmotically driven crystal morphogenesis of polyoxometal

54 Further, we utilize osmotically driven emulsification to tailor the structur

55 te hyperosmotic stimulation, contributing to osmotically driven firing activity in MNNs.

56 Thus, osmotically driven increases in the surface-to-volume ra

57 egenerating Hydra tissue spheroids, periodic osmotically driven inflation and deflation cycles genera

58 The osmotically driven ingress of water leads to an increase

59 Despite their role in osmotically driven lung water transport, aquaporins are

60 Conversely, osmotically driven magnocellular neurosecretory neuronal

61 Osmotically driven membrane processes (including forward

62 Osmotically driven membrane processes (ODMP) have gained

63 solute interactions can affect the design of osmotically driven membrane processes (ODMPs) is critica

64 ed in five additional rabbits implanted with osmotically driven minipumps containing endothelin-1 (0.

65 ural region of the anterior optic nerve with osmotically driven minipumps.

66 ATP and glutamate act in concert to regulate osmotically driven MNN neuronal excitability remains unk

67 e central nervous system and facilitates the osmotically driven pathological brain swelling associate

68 source, thereby providing new support for an osmotically driven refilling mechanism.

69 oparticles by lung parenchymal cells via the osmotically driven regulatory volume decrease (RVD) mech

70 ow bilayered sphere is formed that undergoes osmotically driven shape oscillations of inflation and r

71 Based on previous findings, we combine osmotically driven shape oscillations with tissue mechan

72 lism, we found that it did not supervise the osmotically driven switch in the biological activities o

73 use molecular dynamics simulations to study osmotically driven transport of water molecules through

74 We discuss the implications of this osmotically driven type of surface motility for nutrient

75 k this limitation by taking advantage of the osmotically driven water flux between a droplet containi

76 the semielastic properties of the cell wall, osmotically driven water influx will generate turgor, a

77 um rate of 0.11% s(-1) Analyzing swelling as osmotically driven water influx, we find the H2O membran

78 water-transporting proteins that facilitate osmotically driven water movement across cell plasma mem

79 ) water channels provide a major pathway for osmotically driven water movement across epithelial and

80 sults establish a novel method for measuring osmotically driven water permeability across microvessel

81 f AQP1 in OMDVR water transport, we measured osmotically driven water permeability in vitro in microp

82 These results indicate that osmotically driven water transport across microvessels i

83 nt in mucus clearance, whereas inhibition of osmotically driven water transport by amiloride accounte

84 way epithelium coexists and is distinct from osmotically driven water transport.

85 in alpha-hemolysin (alphaHL), to demonstrate osmotically-driven mass transfer of fluid across surfact

86 the lumen of the colon, which is followed by osmotically-driven water absorption, so we hypothesized

87 dicating that H(+)-driven Cl(-) accumulation osmotically drives vesicle enlargement.

88 nce of septation when grown on a traditional osmotically enhanced medium.

89 les is expected when pores are formed in the osmotically equilibrated membranes, our results support

90 critical for normal fluid balance, mediating osmotically evoked drinking and neurohypophysial hormone

91 e predictions of this model, we find that an osmotically expanding hydrogel responds to step changes

92 Water osmotically follows the release of Cl(-) through ion cha

93 Sodium lactate was substituted iso-osmotically for sodium chloride.

94 tion were viable with mildly spherocytic and osmotically fragile erythrocytes.

95 The headpiece null erythrocytes were osmotically fragile, and ektacytometry/micropore filtrat

96 beta-adducin null RBCs are osmotically fragile, spherocytic, and dehydrated compare

97 imilate carbohydrates that supply growth and osmotically generate turgor, while stomata close to prev

98 bstructions, and phloem flow is driven by an osmotically generated pressure differential according to

99 ted that flow of assimilates is driven by an osmotically generated pressure differential, as proposed

100 Ernst Munch in 1930 describes a mechanism of osmotically generated pressure differentials that are su

101 p is driven through phloem sieve tubes by an osmotically generated pressure gradient between source a

102 anced, finite-difference solution to Munch's osmotically generated pressure-flow hypothesis is develo

103 ungus requires and utilizes melanin-derived, osmotically generated pressures estimated at 80 bars to

104 The amplitude of the osmotically induced [Ca(2+)](cyt) transient was attenuat

105 hanisms must exist that discriminate between osmotically induced and other forms of stress-induced pr

106 ncentrations (< 55 mM) and a second that was osmotically induced at high concentrations (> 55 mM) and

107 Osmotically induced budding of the ATPS-containing GVs l

108 F is released by cultured ECs in response to osmotically induced cell injury.

109 Entpd3), restricts the range and duration of osmotically induced cell migration after injury.

110 Osmotically induced cell swelling and subsequent regulat

111 s suppressed, increasing membrane tension by osmotically induced cell swelling increased FM1-43 fluor

112 We report that osmotically induced cell volume changes, which are known

113 media and inhibited in hypertonic media; the osmotically induced changes in activity occurred within

114 2+) and Ca(2+) influx were also sensitive to osmotically induced changes in cell volume.

115 ilized in a two-dimensional (2D) array, with osmotically induced changes in droplet volume being used

116 We conclude that TRPM7 senses osmotically induced changes primarily through molecular

117 ffusion across cytoplasm was demonstrated by osmotically induced changes to hemoglobin concentration

118 The osmotically induced decrease in ER-beta expression was s

119 sing transporter ProP protects bacteria from osmotically induced dehydration by mediating the uptake

120 o a universal reduction in the expression of osmotically induced genes.

121 Activation of AT1R subtype a by osmotically induced membrane stretch suppresses an XE991

122 t TRPC6 is also a sensor of mechanically and osmotically induced membrane stretch.

123 rginine decarboxylase) responsible for their osmotically induced putrescine accumulation.

124 Analyses of osmotically induced release as well as Ca2+ triggered an

125 The results support the view that the osmotically induced rise in putrescine and blockage of i

126 The yeast TRPY1 is activated in vivo by osmotically induced vacuolar membrane deformation and by

127 Here we analyze osmotically induced vacuole fragmentation by time-lapse

128 rt describes the influence of fluid flow and osmotically induced volume changes on Na(+)-Ca(2+) excha

129 ivity is modulated by both solution flow and osmotically induced volume changes.

130 parietal and visceral tissues are sources of osmotically induced water flow into the cavity.

131 Osmotically induced water transport was rapid in choroid

132 r weight, ester end-capped PLGA displayed an osmotically induced/pore diffusion mechanism based on co

133 data confirm and extend previous reports of osmotically-induced FLI in rat brain and demonstrate tha

134 The level of osmotically-induced TRPV4 activation, although proportio

135 Thus, the SFO is important for the osmotically-induced water drinking response after acute

136 ized, putative AlgU promoter upstream of the osmotically inducible gene osmE.

137 In Saccharomyces cerevisiae, many osmotically inducible genes are regulated by the Sko1p-S

138 pression of a number of stationary-phase and osmotically inducible genes in enteric bacteria.

139 pression of a number of stationary-phase and osmotically inducible genes in Escherichia coli.

140 rane and periplasmic proteins, including the osmotically inducible genes osmB and osmC.

141 sitive and display compromised expression of osmotically inducible genes.

142 Although most of the genes of the osmotically inducible regulon were overexpressed in medi

143 All three genes are osmotically inducible to some degree.

144 The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier prot

145 membrane, and functions as a vehicle for the osmotically inert storage of a variety of granule-bound

146 ., protoplasts or spheroplasts) and comprise osmotically intact, unit-membrane-bound sacs that are ap

147 ions of the impermeable solute sucrose, they osmotically lose ~85% of their cellular water in less th

148 e layered, in a centrifuge chamber, above an osmotically matched dense solution, containing Nycodenz,

149 Importantly, when the swelling rate was osmotically matched for AQP4-positive and AQP4-negative

150 /GSH, and NAD+/NADH and fails to prevent the osmotically mediated depletion of GSH and taurine and th

151 are not absorbed in the colon and induce an osmotically mediated diarrhea; in contrast, SCFA are abs

152 Our ex vivo experiments in osmotically modulated tendon elucidate physical causes o

153 1) the osmotically most sensitive and 2) the osmotically most resistant erythrocyte membranes in an a

154 rocedure to isolate subpopulations of 1) the osmotically most sensitive and 2) the osmotically most r

155 This suggests a model in which osmotically obliged water flows through the stellate cel

156 olling the glial capacity to buffer K(+) and osmotically obliged water.

157 These solutes are acting osmotically on the condensed array.

158 very of bevacizumab into the brain across an osmotically opened BBB is effective, in contrast to the

159 effective delivery into the brain across an osmotically opened BBB.

160 disrupted ER-nuclear membrane contiguity in osmotically or ferroptotically stressed mammalian cells

161 ir growth and division takes place within an osmotically protected environment, and also due to a dri

162 vely within the interior of living cells, an osmotically protected niche.

163 cally require growth for many generations on osmotically protective media with antibiotics or enzymes

164 t (a) there was transport of Gly-Gln into an osmotically reactive space inside the lysosomal membrane

165 -site mutation, additional controls exist to osmotically regulate P1 expression.

166 hyperosmotic stress during infection because osmotically regulated genes were highly induced inside p

167 he corticomedullary axis and quantitation of osmotically regulated genes, allowing the prediction of

168 ated with increased transcription of several osmotically regulated genes.

169 his is best explained by an inhibition of an osmotically regulated inhibitory drive to the magnocellu

170 o ~15-copy-number-stabilized pGA1 behind the osmotically regulated ompC promoter, resulting in high e

171 Unlike most other osmotically regulated promoters, the induction occurs fo

172 In contrast to observations in some other osmotically regulated systems, addition of glycine betai

173 thesis of the osmoprotectant glycerol and is osmotically regulated via the high osmolarity glycerol (

174 1, was transcribed and its transcription was osmotically regulated.

175 day of atomoxetine (N=222), 18-54 mg/day of osmotically released methylphenidate (N=220), or placebo

176 Response was significantly greater with osmotically released methylphenidate than with atomoxeti

177 that for placebo (24%), but the response to osmotically released methylphenidate was superior to tha

178 ecrease in ADHD Rating Scale total score) to osmotically released methylphenidate with response to at

179 d to atomoxetine had previously responded to osmotically released methylphenidate.

180 eter expansions in fusions of membranes from osmotically resistant erythrocytes are faster in the ear

181 rged spheres, so that one mutant synthesized osmotically resistant peptidoglycan when only 2 of 12 PB

182 pneumophila was sodium sensitive, cytotoxic, osmotically resistant, competent to evade macrophage lys

183 riant RING finger protein high expression of osmotically responsive gene (HOS)1 was identified geneti

184 ubiquitin ligase adaptor, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 15 (HOS15), controls the pro

185 lytic enzyme enolase named LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 2 (LOS2) in causing constitu

186 E3-ubiquitin ligase rice HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE1 (OsHOS1), which mediates pr

187 ere, we demonstrated that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1), which is known to

188 Here, we identify HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15 (HOS15) as a core member

189 HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15 (HOS15) constitutes a th

190 sive genes), and hos (for high expression of osmotically responsive genes) mutants were identified by

191 esponsive genes), los (for low expression of osmotically responsive genes), and hos (for high express

192 psis mutant, hos10-1 (for high expression of osmotically responsive genes), in which the expression o

193 of a mutant, hos9-1 (for high expression of osmotically responsive genes), in which the reporter con

194 umber of cos (for constitutive expression of osmotically responsive genes), los (for low expression o

195 Here we report that High Expression Of Osmotically Responsive Genes1 (HOS1) is a regulator of a

196 caused by a lesion in the high expression of osmotically responsive genes1 (HOS1) locus, which encode

197 t the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1) physically interact

198 y the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1).

199 ted DEAD box RNA helicase (LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES4 [LOS4]) that regulates mRN

200 We find similar behavior in the osmotically responsive HOG pathway.

201 ransport into HL60/ADR membrane vesicles was osmotically sensitive and dependent on ATP concentration

202 Drug transport was osmotically sensitive and saturable with regard to drug

203 Drug uptake was osmotically sensitive and saturable with regard to subst

204 As(GS)(3) transport by MRP1 was osmotically sensitive and was inhibited by several conju

205 ded probes and can in principle apply to any osmotically sensitive bioactivity, opening new routes fo

206 d the unusual property of accumulating in an osmotically sensitive cellular compartment of Escherichi

207 v) leaderless DsbA was not transported to an osmotically sensitive compartment via a secA- or ftsZ-de

208 r proton ATPase, responded to changes in the osmotically sensitive intravesicular space, and was satu

209 ggesting the presence of a sodium-conducting osmotically sensitive ion channel.

210 also find evidence that a sodium-conducting osmotically sensitive mechanism contributes to salt resp

211 xpand as far as in fusions of membranes from osmotically sensitive membranes.

212 after bile duct ligation and is regulated by osmotically sensitive miRs.

213 We show that CRP-cAMP functions as an osmotically sensitive repressor of proP P1 transcription

214 -dependent transport in SMP occurred into an osmotically sensitive space and was inhibited by the ant

215 Choline uptake into an osmotically sensitive space was not stimulated by an out

216 le (Km = 62 micromol/L) and occurred into an osmotically sensitive space.

217 the membrane protein thought to mediate the osmotically sensitive taurine efflux.

218 icles show that MRP1 supports ATP-dependent, osmotically sensitive uptake of MX.

219 Furthermore, mutant embryos are osmotically sensitive, allowing us to designate this gen

220 pI::cm mutation rendered growth of the cells osmotically sensitive, and incubation of the insertion m

221 port of MTX into vesicles was ATP-dependent, osmotically sensitive, and inhibited by fumitremorgin C.

222 ly conserved stress-activated p38-type MAPK [Osmotically Sensitive-2 (OS-2)] by the N. crassa circadi

223 whereas Fis and Lac repressor binding is not osmotically sensitive.

224 at low osmotic pressure and rendered growth osmotically sensitive.

225 Vesicles are prepared by lysis of osmotically sensitized cells (i.e., protoplasts or spher

226 To influence water flow, we osmotically shock the cell during cell division, and fin

227 icroscopic assessments of tubular changes in osmotically shocked and control fibres from frog sartori

228 Yet, cells that had been osmotically shocked and treated with paraformaldehyde we

229 Using osmotically shocked cells for protease treatments, the N

230 Electron micrographs of osmotically shocked cells showed a significant decrease

231 endent glycolate or P-glycolate oxidation by osmotically shocked chloroplasts from the algae Dunaliel

232 When crude extracts of French-pressed or osmotically shocked Escherichia coli cells are centrifug

233 otentials from cooled, superficial fibres in osmotically shocked muscles lacked after-depolarization

234 This finding indicates that in osmotically shocked or electroporated bacteria, proteins

235 ly, when keratinocytes are stretched or hypo-osmotically shocked, alpha6beta4 integrin accumulates at

236 erioplankton may actively accumulate DMSP to osmotically significant concentrations that favor near-m

237 Pores that were opened in osmotically stabilized erythrocytes could not be closed

238 rentially infected by P. vivax, are the most osmotically stable.

239 mediated shRNA knockdown of Caprin-2 in the osmotically stimulated hypothalamus shortens the AVP mRN

240 Finally, we studied how the gain of osmotically stimulated oxytocin release changes in the p

241 Osmotically stimulated vasopressin secretion promotes an

242 h low plasma membrane PtdInsP(2) levels were osmotically stimulated, a mild osmotic stress (12.5 mM K

243 also used a range of NaCl concentrations to osmotically stress the rbc's.

244 a primary determinant of the growth rate of osmotically stressed cells.

245 e precipitated by GST-Ssk2p from extracts of osmotically stressed cells.

246 nt with regulation of JNK-1 by p38 kinase in osmotically stressed cells.

247 th up-regulation of native JNK-1 activity in osmotically stressed cells.

248 k but localizes to cortical actin patches in osmotically stressed cells.

249 ne decarboxylase activities decline in these osmotically stressed dicot leaves, while spermidine and

250 and macromolecular crowding in the growth of osmotically stressed Escherichia coli, we have determine

251 nopurification of overexpressed PPIP5K1 from osmotically stressed HEK cells (0.2 M sorbitol; 30 min)

252 response was observed between TNF-alpha and osmotically stressed human liver cells.

253 Osmotically stressed leaves showed increased peak IV kin

254 X-ray diffraction analysis of osmotically stressed LPS multilayers was used to determi

255 nsporter 1 and heat shock protein 70 mRNA in osmotically stressed MDCK cells, blocks cell proliferati

256 inases (MSTs) (members of the Pak family) in osmotically stressed neutrophils and neutrophils treated

257 Inhibiting JNK2 production by siRNA in osmotically stressed PCHCE cells prevented the stimulati

258 Ins(1,4,5)P(3) accumulate in salt, cold, and osmotically stressed plants.

259 hanolica can directly convert to amyloids in osmotically stressed S. cerevisiae cells, providing a un

260 2p, and complement actin recovery defects in osmotically stressed ssk2delta and spa2delta yeast cells

261 f the TNFalpha and lymphotoxin-beta genes in osmotically stressed T cells.

262 ton recovery to the neck of late cell cycle, osmotically stressed yeast cells.

263 citance were observed when the cultures were osmotically stretched.

264 By osmotically suppressing DNA release from HSV-1 capsids,

265 Charged hyaluronate polymers osmotically swell with water and generate isotropic extr

266 sely, when membrane tension was increased by osmotically swelling cells, the extension rate decreased

267 We observe that in osmotically swollen cells the beta2-adrenergic receptor,

268 n reveals an unusual structure consisting of osmotically swollen stacks of composite membranes with n

269 cture of BtuB in its holo form represents an osmotically trapped conformation.

270 f macrophages and lymphocytes, which present osmotically variable environments, and hydration-depende

271 oreover, cells on the microarrays were lysed osmotically with Milli-Q(TM) water and the infiltration

272 lmost universally believed), or because they osmotically withdraw a large fraction of intracellular w