ライフサイエンスコーパス: osteochondral

1 s a surrogate biomarker for success of shell osteochondral allograft implantation.

2 Many large centers have abandoned osteochondral allografts and resection arthrodesis for t

3 at the osteochondral junction were assessed (osteochondral angiogenesis).

4 PPI-2458 treatment reduced synovial and osteochondral angiogenesis, synovial inflammation, joint

5 ndral defects, including marrow stimulation, osteochondral auto- and allografting, and autologous cho

6 Under video microscopy, pairs of osteochondral blocks from each core were apposed, compre

7 oncept model with IL-1beta-stimulated bovine osteochondral (bOC) explants treated with MaR1, RvD1, or

8 ast number, suggestive of an early arrest of osteochondral bone formation.

9 Specifically, NGFR is expressed in osteochondral cells but not in skeletal progenitor cells

10 lowing in vivo implantation of the bilayered osteochondral constructs in the dorsum of immunodeficien

11 Osteochondral cores from femoral condyles of cadaveric h

12 Human osteochondral cores from lateral femoral condyles, chara

13 The osteochondral cores from tissue donors were macroscopica

14 Osteochondral cores were harvested from the knees of cad

15 In vivo, the rabbits with osteochondral critical-size defects receiving the ultras

16 e OA provides a good model to study this, as osteochondral damage is commonly more severe in the medi

17 acterized by marked cartilage friability and osteochondral debonding.

18 post-implantation in a rabbit full thickness osteochondral defect model, the quality of regenerative

19 ssue regeneration in a rabbit full-thickness osteochondral defect model.

20 d mitomycin-pretreated apoptotic ADSCs in an osteochondral defect of the left femur.

21 ble adipose-derived stem cells (ADSCs) in an osteochondral defect of the right femur and mitomycin-pr

22 formed better cartilage matrix in an ex vivo osteochondral defect than control settings.

23 ty cartilage fracture line, and fluid-filled osteochondral defect).

24 the same MSCs were injected in rats with an osteochondral defect, allowing MR monitoring of their en

25 In a critical-size rabbit osteochondral defect-repair model, the nanofibrous hollo

26 be misinterpreted as an articular erosion or osteochondral defect.

27 artilage architecture was established in rat osteochondral defects after treatment with chondrogenica

28 I can provide excellent anatomical detail of osteochondral defects and demonstrate similar features t

29 model, we implanted the scaffold in shallow osteochondral defects and found it can remain localized

30 Osteochondral defects contain damage to both the articul

31 24.4 msec; P < .05) and could be tracked in osteochondral defects for 4 weeks.

32 labelled MSC injected into joints containing osteochondral defects in experimental sheep.

33 ntly improved repair of hyaline cartilage in osteochondral defects injected with the scaffold relativ

34 eled cells were subsequently transplanted in osteochondral defects of 14 knees of seven athymic rats

35 ntly lower than those of matched implants in osteochondral defects of female rats (mean, 10.72 msec f

36 or mismatched stem cells were implanted into osteochondral defects of the knee joints of experimental

37 Rabbits with critical-sized osteochondral defects receiving the piezoelectric scaffo

38 When implanted into rat osteochondral defects, acellular nanofiber scaffolds sup

39 Besides the pigmentation and osteochondral defects, usb1-knockdown caused defects in

40 spontaneous healing of focal chondral versus osteochondral defects.

41 etically engineered MDSCs implanted into rat osteochondral defects.

42 reasing shear, which eventually leads to the osteochondral degeneration.

43 st computed tomography showed sinusitis with osteochondral destruction, bronchiectasis, mucus pluggin

44 For the 59 myotendinous and the 48 osteochondral diagnoses, the sensitivity, specificity, a

45 A-expressing axonal ingrowth drives abnormal osteochondral differentiation after soft tissue trauma.

46 under certain contexts, results in aberrant osteochondral differentiation of tissue-specific stem ce

47 ead to similar delays in axonal invasion and osteochondral differentiation.

48 progress to parasagittal fractures or palmar osteochondral disease (POD).

49 Osteochondral explants obtained from mature cattle were

50 he top layers of cartilage were removed from osteochondral explants, and the residual cartilage was a

51 subchondral cyst (six patients) or a single osteochondral fragment (two patients).

52 tion, and early motion are primary goals for osteochondral fragment preservation.

53 aled that GPR103-/- mice exhibited a thinned osteochondral growth plate, a thickening of trabecular b

54 formalin-fixed paraffin-embedded (FFPE) KOA osteochondral (i.e., cartilage-subchondral bone) tissues

55 ngs related to tendinopathy, ligamentous and osteochondral injuries, and instability of the elbow.

56 m of entities discussed includes osseous and osteochondral injuries, ligamentous injuries, common tra

57 ndinitis and tear, and suspected osseous and osteochondral injuries.

58 tis affect chondrocyte gene expression using osteochondral injury models with synovial co-culture.

59 significantly lower peak modulus, and at the osteochondral interface do not have a calcified cartilag

60 es tended to involve the inner aspect of the osteochondral interface with an associated osseous fragm

61 or target in complex tissue engineering: the osteochondral interface.

62 l junction, a diagonal-plane junction and an osteochondral interface.

63 noted in the vascular channels breaching the osteochondral junction in lateral condyles.

64 Channels positive for vessels at the osteochondral junction were assessed (osteochondral angi

65 new bone formation in osteophytes and at the osteochondral junction, thereby contributing to radiolog

66 ited a high-intensity linear signal near the osteochondral junction, which was not visible on protein

67 hy, osteophytosis, and channels crossing the osteochondral junction.

68 y of evaluating abnormalities at or near the osteochondral junction.

69 n T2 in superficial region of interest in an osteochondral lesion = 50.0 msec +/- 10.2) in comparison

70 A massive osteochondral lesion was created in the hip of skeletall

71 i.e., soft tissue lateral ankle impingement, osteochondral lesion, or partial peroneal tendon tear).

72 ation, 49.2 years +/- 12.7) with chondral or osteochondral lesions were prospectively collected and r

73 Cs and improved early stage tissue repair of osteochondral lesions when transplanted, along with a co

74 t modulation of focal adhesion formation and osteochondral lineage commitment was observed as a funct

75 the CTR9-H3K27me3-BMP-2 axis to regulate the osteochondral lineage differentiation of hMSCs.

76 growth factor that is highly specific to the osteochondral lineage, and has demonstrated robust induc

77 Six-millimeter-diameter chondral (n = 5) and osteochondral (n = 5, 3-4 mm deep into subchondral bone)

78 in ectopic mouse models reproducing a human osteochondral OA tissue environment, as well as in sheep

79 account in the case of biofabrication of the osteochondral (OC) interface.

80 and CA(4+) to GAGs in cartilage (six bovine osteochondral plugs) were quantified by means of a modif

81 The osteochondral potential of the isolated cells was also a

82 CC frontal dysfunction to a stage of altered osteochondral progenitor differentiation.

83 sensory nerve fibers, which are required for osteochondral progenitor expansion during mammalian skel

84 primordium, in addition to mesoderm-derived osteochondral progenitors.

85 SWIFT enabled assessment of spontaneous osteochondral repair in an equine model.

86 ultiparametric qMRI maps, obtained for eight osteochondral samples on a clinical 3.0 T MRI scanner.

87 ation tests were performed with fresh bovine osteochondral samples.

88 An early osteochondral SSC (ocSSC) facilitates long bone growth a

89 is very limited and pertains only to massive osteochondral surgery for trauma or malignancy, and is c

90 water content) contrast agents inside human osteochondral tissue (n = 53).

91 ontribute to biomechanical alteration of the osteochondral tissue and its subchondral bone plate comp

92 ding, increased hydraulic conductance of the osteochondral tissue and subchondral bone plate could ha

93 hypothesis was that hydraulic conductance of osteochondral tissue and subchondral bone plate increase

94 Hydraulic conductance of native osteochondral tissue and subchondral bone plate was high

95 ineralization in order to produce integrated osteochondral tissue constructs.

96 chondral tissue repair and holds promise for osteochondral tissue engineering applications.

97 hydrogel platform could effectively augment osteochondral tissue regeneration holds promise for a fe

98 d/or insulin-like growth factor-1 (IGF-1) on osteochondral tissue regeneration in a rabbit full-thick

99 rticles (GMPs) and stem cell populations for osteochondral tissue regeneration.

100 lternative tissue engineering strategies for osteochondral tissue regeneration.

101 yered composite hydrogels positively affects osteochondral tissue repair and holds promise for osteoc

102 lls (ADSCs) would synergistically facilitate osteochondral tissue repair during physiological regener

103 distinctive hierarchical structure of native osteochondral tissue was utilized to investigate the eff

104 cteristics as seen in vascularized bones and osteochondral tissues.

105 This totally different constitution of the osteochondral unit in aquatic mammals reflects that acco

106 These comprehensive analyses of the entire osteochondral unit with multiple standardized evaluation

107 of loading is the primordial function of the osteochondral unit.

108 We compared the osteochondral units of the humeral head of marine and te

109 ted into athymic rats significantly enhanced osteochondral wound healing with reduced vascularisation