コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 into osteoblasts at sites that are innately osteogenic.
2 erm culture-induced MSC aging impaired their osteogenic ability and subsequent bony callus formation,
3 mBMSCs with Msx1 and Msx2 genes and compared osteogenic activity and expression levels of several Msx
5 nalling in C2C12 does not translate into non-osteogenic activity in vivo and BMP10 also induces bone-
6 olecular strategies are toward promoting pro-osteogenic activity of BMP2 while simultaneously suppres
9 Prolonged culture-associated decreases in osteogenic and adipogenic capacity were partially protec
10 g epigenetic modifications that occur during osteogenic and adipogenic differentiation of mouse bone
11 ifferentiation capacity of these stem cells, osteogenic and adipogenic differentiation was achieved.
12 igher expression of SPP1 and LEP, markers of osteogenic and adipogenic differentiation, respectively.
13 drogel constructs can be differentiated down osteogenic and adipogenic lineages, giving rise to self-
17 covered that global Notch inhibition reduces osteogenic and chondrogenic differentiation of FCSCs.
19 istinct subpopulation of MSCs, with enhanced osteogenic and decreased adipogenic differentiation capa
20 scription factor 2-mediated (Runx2-mediated) osteogenic and decreased PPARgamma-dependent adipogenic
22 concentration for microspheres, the combined osteogenic and mineralization effect of PRP and BMP2 on
23 However, the molecular mechanisms underlying osteogenic and myogenic differentiation by FN in C2C12 p
25 , the authors compared and evaluated the pro-osteogenic and pro-odontogenic effects of 4 small bioact
26 ssive stiffness simultaneously increased the osteogenic and proangiogenic potential of entrapped cocu
28 helial growth factor (VEGF) on the extent of osteogenic and vasculogenic differentiation of human mes
32 stem cells and plasmids encoding for either osteogenic (BMP2) or chondrogenic (combination of TGF-be
39 BM-MSCs seemed to have low proliferative and osteogenic capacities; therefore, enhancing their qualit
40 afts from aged animals with L-WNT3A restored osteogenic capacity to autografts back to levels observe
43 fibroblasts respond to injury by adopting an osteogenic cell fate and creating damaging calcific depo
44 ression of Runx2 and Col1a1, which are early osteogenic cell markers, on day 10 after the subperioste
47 differentiation efficiency and they generate osteogenic cells comparable to osteogenic cells derived
48 they generate osteogenic cells comparable to osteogenic cells derived from mesenchymal stromal cells
49 rapeutic paradigms to augment the endogenous osteogenic cells for bone regeneration and the treatment
50 of pro-angiogenic potential of transplanted osteogenic cells for effective cell-mediated bone repair
52 n to multiple phenotypes including Lgals3(+) osteogenic cells likely to be detrimental for late-stage
53 Bq for total body, 0.21 +/- 0.15 cGy/MBq for osteogenic cells, and 0.17 +/- 0.15 cGy/MBq for kidneys.
54 y, pretreatment of p38 inhibitor followed by osteogenic challenge impaired osteoblastogenesis via sup
57 bone sclerosis has been linked to heightened osteogenic commitment of bone marrow stromal cells (BMSC
61 anscription proteins (STATs) in myogenic and osteogenic differentiation after FN treatment were also
62 ration and survival capacities, reduction in osteogenic differentiation and a decrease in the ability
63 to investigate the effects of soluble Si on osteogenic differentiation and connexin 43 (CX43) gap ju
64 redox ratio decreased for VICs during early osteogenic differentiation and correlated with biologica
65 alveolar bone regeneration through enhancing osteogenic differentiation and decreasing stromal cell-d
66 rolonged calcifying conditions by inhibiting osteogenic differentiation and increases in nSMase2 thro
67 investigate the action of FN on myogenic and osteogenic differentiation and its impact on signaling p
68 lation of BMP4-pSMAD1/5 signaling, decreased osteogenic differentiation and lowered proliferation cap
69 the regulation of AP-1 pathway genes and for osteogenic differentiation and matrix mineralization.
70 of autophagy before day 3 strongly inhibited osteogenic differentiation and mineralization of ASCs in
71 rated the attachment, spread, proliferation, osteogenic differentiation and mineralization of MC3T3-E
72 acute myeloid leukemia impaired mesenchymal osteogenic differentiation and reduced regulatory molecu
73 dence that 25(OH)D3 at 250-500 nM can induce osteogenic differentiation and that 25(OH)D3 has great p
75 ioactive, capable of stimulating odontogenic/osteogenic differentiation as observed by gene expressio
76 s induced by osteogenic stimuli and promotes osteogenic differentiation at least partly by targeting
77 tion in human smooth muscle cells undergoing osteogenic differentiation attenuated matrix mineralizat
78 that these hESCs/hiPSCs are similar in their osteogenic differentiation efficiency and they generate
79 inB1-EphB2 interaction regulates odontogenic/osteogenic differentiation from dental pulp cells (DPCs)
80 we examined effects of OA on cell viability, osteogenic differentiation in MSCs, and the involvement
82 g medium, which in turn efficiently enhanced osteogenic differentiation in vitro and osteointegration
83 PRP from alginate beads on BMP2-modified MSC osteogenic differentiation in vitro and sustained releas
84 ated a reduction in cell survival and direct osteogenic differentiation in vitro These effects were m
86 NA mediated gene silencing to understand the osteogenic differentiation observed on fibrous scaffolds
88 ively, our findings indicate Cdo1 suppresses osteogenic differentiation of BMSCs, through a potential
91 bone morphogenetic protein-2/BMP-2-directed osteogenic differentiation of bone marrow stromal cells
92 ontrolled release of Ade and facilitated the osteogenic differentiation of bone mesenchymal progenito
93 significantly improved potential for odonto/osteogenic differentiation of DPSCs both in vivo and in
95 marrow stromal cells cultured in microwells, osteogenic differentiation of encapsulated cells depends
97 how that cyclic tensile strain both enhances osteogenic differentiation of hASCs while it suppresses
99 ersed the promoting or suppressing effect of osteogenic differentiation of hBMSCs, respectively, caus
100 e PLZF transcription factor is essential for osteogenic differentiation of hMSCs; however, its regula
101 ary cilia are involved in chemically-induced osteogenic differentiation of human ASC (hASCs) in vitro
102 e expression of miR-101 and its roles in the osteogenic differentiation of human bone marrow-derived
103 e, we investigated the effect of 25(OH)D3 on osteogenic differentiation of human mesenchymal stem cel
104 niques to synergistically improve growth and osteogenic differentiation of human mesenchymal stem cel
105 strated through localized cell spreading and osteogenic differentiation of human mesenchymal stem cel
106 and cartilage homeostasis by influencing the osteogenic differentiation of hypertrophic chondrocytes
107 of RhoA and ROCK activity partially restores osteogenic differentiation of IFT80-deficient OPCs by in
109 well as on the adhesion, proliferation, and osteogenic differentiation of MC3T3-E1 pre-osteoblastic
110 find that cell spreading, proliferation, and osteogenic differentiation of mesenchymal stem cells (MS
111 vealed enhanced focal adhesion formation and osteogenic differentiation of MSCs cultured on positivel
114 uring bone healing favours chondrogenic over osteogenic differentiation of skeletal progenitor cells.
115 he potential of plant-produced OPN to induce osteogenic differentiation of stem cells from periodonta
124 ncreasing vascular smooth muscle cell (VSMC) osteogenic differentiation, ADAM17-induced renal and vas
125 ll LIV signals enhanced hBMSC proliferation, osteogenic differentiation, and upregulated genes associ
127 from Clec11a-deficient mice showed impaired osteogenic differentiation, but normal adipogenic and ch
130 d in response to culture in complete growth, osteogenic differentiation, or adipogenic differentiatio
131 did not affect cell viability, apoptosis, or osteogenic differentiation, perhaps due to increased exp
132 Ppia(-/-) osteoblasts demonstrate decreased osteogenic differentiation, whereas Ppia(-/-) osteoclast
134 role of magnesium in promoting CGRP-mediated osteogenic differentiation, which suggests the therapeut
161 studies demonstrate the importance of the 3D osteogenic-endothelial niche interaction in bone regener
164 The addition of recombinant mDKK1 switched osteogenic ESC differentiation toward chondrogenic diffe
165 eural EGFL-like 1 (Nell-1) is a well-studied osteogenic factor that has comparable osteogenic potency
166 re implanted ectopically in combination with osteogenic factors into mice to generate a physiological
167 ation, these IS cells differentially express osteogenic factors, mechanosensitive genes, and signalin
168 of stem cells with the controlled release of osteogenic factors, within a mechanically-strong biomate
171 a valuable experimental tool to distinguish osteogenic from dentinogenic cells, thereby providing an
174 yses of Mkx(-/-) PDL revealed an increase in osteogenic gene expression and no change in PDL- and inf
175 graphy on altering cell-cell interaction and osteogenic gene expression at the single cell level.
176 roliferation with a concomitant reduction of osteogenic gene expression, and prevention of craniosyno
178 hat in mobile MPCs, chromatin regions around osteogenic genes are open, whereas in immobile MPCs, reg
180 t the CaSr-MOFs by themselves can upregulate osteogenic genes in hMSCs, which is the first time to ou
183 n was associated with elevated expression of osteogenic genes, decreased expression of pro-inflammato
186 cing analyses, we found that genes vital for osteogenic identity were linked to RUNX2, C/EBPbeta, ret
187 med to identify the transcriptome profile of osteogenic induced ASCs to understand the associated gen
188 4, 14, and 24 in terms of responsiveness to osteogenic induction media and/or stimulation with rhPTH
190 ing JAK1-STAT1 phosphorylation levels, while osteogenic induction was enhanced by p38MAPK dependent S
191 ession in PDL-CD105(+) cells after 7 days of osteogenic induction, although mineral nodule formation
192 PCL+FA and PCL scaffolds to investigate the osteogenic inductive ability of FA crystals and we obser
193 onse in a FZD-selective fashion, enhance the osteogenic lineage commitment of primary mouse and human
194 ndeed, biophysical stimuli potently regulate osteogenic lineage commitmentin vitro In this study, we
195 anobiology model, mechanical signals enhance osteogenic lineage commitmentin vivoand that the primary
196 ng a lineage autonomous function of Shox2 in osteogenic lineage fate determination and skeleton patte
198 ls to bone surfaces and the commitment to an osteogenic lineage of these cellsin vivo Furthermore, we
206 reased in vitro bone formation and decreased osteogenic marker gene expression; promoter methylation
207 as well as gene expression of Alpl and other osteogenic marker genes in mouse osteoblasts and mesench
209 ed surfaces that upregulate expression of an osteogenic marker, we used genetic crossover and random
210 were accompanied by increased expression of osteogenic markers and intramembranous bone formation an
211 tal dimension correlated with structural and osteogenic markers as well as measures of nuclear morpho
212 unced upregulation of osteopontin and RUNX2 (osteogenic markers), CD63, AnX2 (sEV markers) and ALP ex
214 further required for eventual expression of osteogenic markers, and RARG-antagonist strongly drives
215 ion conditions, as evidenced by increases in osteogenic markers, including Runt-related transcription
220 althy controls and cultured up to 24 d using osteogenic medium with standard phosphate concentration.
225 cacy and safety of periodontally accelerated osteogenic orthodontics (PAOO) with "Piezocision"-a mini
226 ly increased and expanded expression of many osteogenic pathway genes, including Bmp3, Bmp5, Bmp7, Me
227 that suggested a default preference for the osteogenic pathway; however, these patterns were rapidly
229 experiments showed that H19 induces a strong osteogenic phenotype by altering the NOTCH1 pathway.
230 n advanced lesions, including Klf4-dependent osteogenic phenotypes likely to contribute to plaque cal
232 tudied osteogenic factor that has comparable osteogenic potency with the Food and Drug Administration
233 ith limited differentiation capacity, having osteogenic potential (PC-O) or angiogenic support functi
234 esenchymal stem/stromal cells (MSCs) possess osteogenic potential and produce numerous angiogenic gro
235 DLX3 mutation (c.533 A>G; Q178R) attenuates osteogenic potential and senescence of bone mesenchymal
238 al that nuclear mechanosensing controls hMSC osteogenic potential mediated by HDAC epigenetic remodel
240 d within a bone defect site to determine the osteogenic potential of the skeletal-endothelial cell un
242 aspirin (ASA) on the proliferative capacity, osteogenic potential, and expression of growth factor-as
243 Here, we report DP-MSCs exhibit increased osteogenic potential, possess decreased adipogenic poten
246 sed bone formation by compensating decreased osteogenic potentials with more generations and extended
248 e role of exogenous factors in driving these osteogenic processes will aid the development of better
249 ry of ligands that not only bind strongly to osteogenic progenitor cells (OPCs) but also stimulate os
250 and basic fibroblast growth factor in these osteogenic progenitor cells are markedly different, sugg
251 a femur non-union fracture demonstrate only osteogenic progenitor cells with higher pro-angiogenic p
252 lpha and Sca-1 than the Sca-1-negative adipo-osteogenic progenitors, which create a niche for hematop
254 expression of this lncRNA, which promotes an osteogenic program by interfering with the expression of
255 ion of several Wnt genes, BMP2 activates the osteogenic program largely independently of de novo Wnt
260 out undesirable estrogenic activity and with osteogenic properties, we are now interested in validati
262 s and a higher expression of osteocalcin -an osteogenic protein known to be promoted by physical exer
263 s, as well as the advantages of Nell-1 as an osteogenic protein with antiadipogenic, anti-inflammator
264 olds demonstrated volumetrically significant osteogenic regeneration of calvarial and alveolar defect
265 Deficiency of Cx43 delayed mesenchymal and osteogenic regeneration while in vivo AMPK inhibition in
268 rtant role of the proteasomal degradation of osteogenic regulators, while the underlying molecular me
269 1 by siRNA led to an increased expression of osteogenic related genes, elevated alkaline phosphatase
271 to healthy levels rescues the epigenetic and osteogenic response in hMSCs with pathological nuclear m
273 te the role of primary cilia in EFS-enhanced osteogenic response of human adipose-derived stem cells
274 to knockdown BMP-2 production abrogated the osteogenic response to levels observed with MSCs alone.
277 ated respectively with greater expression of osteogenic RUNX2 and with lower expression of several in
280 last cells, P3 had no effect on BMP9-induced osteogenic signalling, which is primarily mediated by AL
281 icone gels we show that harder gels are more osteogenic, softer gels are more adipogenic, and cell sp
283 rinted by accurate positioning of a layer of osteogenic spheroids onto a sacrificial alginate support
284 three dimensions (3D) into chondrogenic and osteogenic spheroids, which were confirmed by immunostai
285 Treatment with p38 inhibitors following osteogenic stimulation efficiently induced osteoblast di
286 hese data suggest that miR-101 is induced by osteogenic stimuli and promotes osteogenic differentiati
289 ocked and that differentiation switches from osteogenic to chondrogenic, a process that could be mimi
292 iRNA transfection promoted the expression of osteogenic transcription factors in normal jaw bone MSCs
293 ylates and induces the nuclear import of the osteogenic transcription regulator nuclear factor of act
294 Cre expressing cells as a cell of origin for osteogenic tumor and suggested the LKB1-mTORC1 pathway a
297 ating the component cell interactions in the osteogenic-vascular niche and the role of exogenous fact
298 osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid.