ライフサイエンスコーパス: osteoid

1 lasts display polarised behaviour to deposit osteoid.

2 y of the bone in which spindle cells produce osteoid.

3 ding to adipose (4 kPa), muscle (13 kPa) and osteoid (30 kPa) tissues respectively by exposing them t

4 eralized bone forms when collagen-containing osteoid accrues mineral crystals.

5 thin dentin, lack of acellular cementum, and osteoid accumulation in alveolar bone.

6 uding radiolucencies and resorptive lesions, osteoid accumulation on the alveolar bone crest, and sig

7 non-mineralized polymer scaffold (19 +/- 8% osteoid and 10 +/- 2% mineralized tissue).

8 biopsy specimens revealed numerous areas of osteoid and bone formation around FDBA particles, with n

9 Although D2J mice showed decreased osteoid and mineralization surfaces, their osteoblasts w

10 ed with decreased trabecular bone volume and osteoid and osteoblast surfaces in postmenopausal osteop

11 nd length of trabecular surface covered with osteoid and up-regulates bone marker gene (OPN, Cbfa1, C

12 ing CMF bone matrix also had an abundance of osteoid, and in locations where compact lamellar bone ty

13 expanded alveolar bone with accumulation of osteoid, and micro-CT confirmed decreased bone volume fr

14 there was no significant difference in total osteoid between the two samples, suggesting that increas

15 lastic bone resorption with simultaneous new osteoid/bone formation in the absence of ascorbate (vita

16 collagen synthesis and the formation of new osteoid/bone.

17 sed as the osteoblast differentiates into an osteoid cell or osteocyte, first appearing on the formin

18 bone porosity (pore water and total water), osteoid density (bound water [BW]), morphologic structur

19 , morphologic structure, mineralization, and osteoid density are affected in postmenopausal osteoporo

20 , morphologic structure, mineralization, and osteoid density are useful measures of bone health.

21 In contrast, new bone and osteoid formation and osteoblast numbers were increased

22 Osteoid formation and osteocalcin expression were descri

23 y, and more distorted growth plate with more osteoid formation in the trabecular region.

24 lized tissue generation, but not necessarily osteoid formation.

25 oci of endosteally localized cells and human osteoid generation.

26 rocomputer tomography), and the formation of osteoids (histologically).

27 al heads, supporting a greater proportion of osteoid in the diseased tissue.

28 tly, osteoblast development and synthesis of osteoid in the nascent bone collar was uncoupled from th

29 An osteoid-inspired biomaterial-demineralized bone paper-di

30 An osteoid-inspired DBP supports rapid and structural miner

31 SC) clusters, leading to formation of marrow osteoid islets accompanied by high levels of angiogenesi

32 Cancellous bone volume and osteoid markers correlated with bone mineral density mea

33 ates, adjusted apposition rates) and static (osteoid markers, osteoblast number) parameters of bone f

34 the splenic nodules revealed the presence of osteoid matrices and osteocytes trapped within mineraliz

35 rate significantly increased regeneration of osteoid matrix (32 +/- 7% of total tissue area; mean +/-

36 tion, shown by accumulation of unmineralized osteoid matrix and interglobular patterns of protein dep

37 The majority (55 cases) demonstrated osteoid matrix mineralization; 17 showed marked minerali

38 trengthened by observations showing that the osteoid matrix that is responsible for implant osseointe

39 the presence of transformed cells producing osteoid matrix, even if these cells comprise a minority

40 and this loss was characterized by impaired osteoid mineralization and bone formation.

41 While osteoid mineralization is initiated at normal rate, mine

42 Moreover, an increased endocortical osteoid mineralization rate and higher trabecular and co

43 the primary spongiosa with reduced immature osteoid (new bone formation) and overall length, which l

44 the block specimens exhibited no evidence of osteoid or active bone formation, but large marrow space

45 tions revealed no differences in osteoblast, osteoid, or osteoclast surface areas.

46 MR imaging features of osteoid osteoma (edema, hyperemia, and nidus vasculariza

47 ded radiofrequency ablation [RA] therapy for osteoid osteoma (OO).

48 ndings that were diagnostic for nonvertebral osteoid osteoma and no contraindications to MR imaging-g

49 se, lower extremity injuries in toddlers and osteoid osteoma are emphasized.

50 ef and the other experienced a recurrence of osteoid osteoma at 11 months, which was successfully tre

51 ale; mean age, 21 years) with a diagnosis of osteoid osteoma based on clinical and imaging findings.

52 CT-guided cryoablation for the treatment of osteoid osteoma between January 2013 and June 2019 in a

53 at MR-guided focused ultrasound treatment of osteoid osteoma can be performed safely with a high rate

54 Osteoid osteoma characteristics, procedure overview, and

55 olinium-enhanced MR imaging demonstrated the osteoid osteoma equally well in eight of 11 patients and

56 ing, the edema and hyperemia associated with osteoid osteoma gradually disappeared in all lesions.

57 One osteoid osteoma had peak enhancement in the venous phase

58 Biopsy results revealed osteoid osteoma in 10 patients, chondroblastoma in one,

59 monstrate secondary radiological findings of osteoid osteoma in both paediatric and adult patients.

60 rable treatment option for the management of osteoid osteoma in children and young adults.

61 Of the 97 patients who had osteoid osteoma in lower extremities or pelvic bones, 73

62 bone location, bone segment, location of the osteoid osteoma in relation to the native cortex, nidus

63 ) of 11 patients had peak enhancement of the osteoid osteoma in the arterial phase with early partial

64 CT-guided cryoablation for the treatment of osteoid osteoma in young patients and adults.

65 CT-guided percutaneous RF ablation of osteoid osteoma is a safe and effective technique.

66 Diagnosis of osteoid osteoma may be delayed if secondary radiological

67 echniques were scored for conspicuity of the osteoid osteoma relative to the surrounding bone.

68 ve and should become the method of choice in osteoid osteoma treatment because of its minimal invasiv

69 f cryoablation have not been established for osteoid osteoma treatment.

70 d, 263 patients who were suspected of having osteoid osteoma underwent 271 ablation procedures.

71 In 89.4% of these, osteoid osteoma was localised in the joint.

72 Conclusion Osteoid osteoma was safely, effectively, and durably tre

73 ion (ILA) on the management of patients with osteoid osteoma was studied.

74 Consecutive patients with osteoid osteoma were assessed before the interventional

75 y ablation is now the standard treatment for osteoid osteoma, as the procedure can be performed with

76 wever, in the 10 patients with biopsy-proved osteoid osteoma, puncture of the tumor caused the mean c

77 CT-guided cryoablation for the treatment of osteoid osteoma, with a 96% (48 of 50 patients) overall

78 t of a routine strategy for the treatment of osteoid osteoma.

79 increase significantly at needle puncture of osteoid osteoma.

80 d by anti-inflammatory drugs may point to an osteoid osteoma.

81 intraarticular (69% in paediatric patients) osteoid-osteoma.

82 Osteoid osteomas can be imaged with greater conspicuity

83 Diaphyseal osteoid osteomas demonstrate a lower ratio of nidus mine

84 The nidus mineralization ratio of osteoid osteomas increases significantly with pain durat

85 dolinium-enhanced MR images demonstrated the osteoid osteomas significantly better than the nonenhanc

86 6% of tumours were intracortical, and 83% of osteoid osteomas were extra-articular.

87 Eighty-three per cent of osteoid osteomas were located in lower extremities, 56%

88 In long bones, diaphyseal osteoid osteomas were significantly less mineralized tha

89 es of 11 patients with pathologically proven osteoid osteomas who underwent nonenhanced MR imaging, d

90 six patients with histopathologically proven osteoid osteomas, complete clinical files, and CT data w

91 compass enchondromas, aneurysmal bone cysts, osteoid osteomas, giant-cell lesions of bone, bone sarco

92 cular bone parameters) and histomorphometry (osteoid parameters).

93 Except for percentage osteoid perimeter, there was no difference in bone histo

94 lines, and that binding results in decreased osteoid production in vitro.

95 lytic lesion formation by causing decreased osteoid production in vivo.

96 radiographic mineralization and histological osteoid production, the differentiation state of tumors

97 terized by severe osteoporosis and decreased osteoid production.

98 s significantly increased; as a consequence, osteoid seams were evident throughout the facial skeleto

99 O bones were hypo-mineralized with prominent osteoid seams, analogous to the phenotypes of mice with

100 duction in osteoid volume to bone volume and osteoid surface to bone surface.

101 lume, trabecular number, osteoblast surface, osteoid surface, and bone-formation rate.

102 d mineralization lag time, as well as higher osteoid surface, osteoblastic surface, resorption surfac

103 e formation rate, inter-label thickness, and osteoid surface, which were increased by FGF23Ab.

104 It also increased osteoid surfaces and, importantly, bone formation rates.

105 ng decrease in the rate of mineralization of osteoid that occurred despite an unexpected osteoblast a

106 hat Dkk2-null mice have increased numbers of osteoids, these data indicate that Dkk2 has a role in la

107 e investigate osteoblast 'burial' within the osteoid they deposit.

108 one at 6 wk revealed significant increase in osteoid thickness, osteoblast number, erosion surface wi

109 stologic components (fibrous, chondroid, and osteoid), tumor grade, and marrow involvement.

110 ocusing on the main protein component of the osteoid, type I collagen.

111 Risedronate did associate with increased osteoid volume and trabecular thickness in male particip

112 ysis demonstrates a significant reduction in osteoid volume to bone volume and osteoid surface to bon

113 increased in all KOs, partially mineralized osteoid volume was increased in dKO versus controls at P

114 with ADPKD demonstrated significantly lower osteoid volume/bone volume (0.61 vs. 1.21%) and bone for

115 The transport of osteoid water across the mineralized matrix of bone was

116 collagen type I is the main component of the osteoid, we hypothesized that the bone vasculature guide

117 atrix markers and existence of unmineralized osteoid were seen at M3 and M14.