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1 ge, as a critical global concern, has fueled our efforts to address it through different strategies.
2                                    We report our efforts to address these challenges, with the goal o
3                                           In our efforts to address this issue, we generated a panel
4                   In this paper, we describe our efforts to apply a wide variety of standard, photo-,
5         This was a remarkable achievement in our efforts to appreciate how the aberrant function of R
6 ve to neuroimaging technologies and enhances our efforts to assess the impact of chemical exposures o
7 bserved and also reflect on what has allowed our efforts to be both successful and sustainable.
8 sed, it remains largely untested, motivating our efforts to benchmark pI prediction methods.
9 ies, Anthoceros agrestis, is instrumental in our efforts to better understand not only hornwort biolo
10 Studies employing BA14K should contribute to our efforts to better understand the antigenic specifici
11 o conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture
12 ems with the proposed secondary structure in our efforts to build a three-dimensional model that is c
13                                   As part of our effort to characterize the Ap4A receptor building do
14                                           In our effort to characterize the signal-transduction pathw
15                                           In our effort to characterize three nucleotide mutations of
16                                           In our efforts to characterize downstream mediators of CD40
17                               We here report our efforts to characterize electric resistances in a CD
18                                   As part of our efforts to characterize more fully the structural fe
19 he results of mutagenesis studies as well as our efforts to characterize the initial steps of the PAD
20                                       During our efforts to characterize the regulatory properties of
21 ons in immunocompromised patients, underline our efforts to characterize viral immunoevasins, such as
22                                              Our efforts to clarify these relationships have revealed
23                                       During our efforts to clone this gene we also isolated a phage
24                                         Even our efforts to combine replicating compartments and gene
25 ve transformations of hydrocarbons, prompted our efforts to conduct an in-depth investigation of a ra
26                  In this review, we describe our efforts to create a form of gene-targeted radiation
27                                 We report on our efforts to create an on-chip system to simultaneousl
28 aining side chain was recently identified in our efforts to create novel antidepressants that act as
29                                           In our efforts to define a cancer dependency map, we perfor
30                                              Our efforts to define molecular correlates of SVC112 sen
31                                           In our efforts to define the genes overexpressed in carcino
32                                           In our efforts to define the specific mechanisms for bacter
33                                           In our efforts to define the structural elements required f
34                                              Our efforts to delineate these pathways in primary murin
35 s, it is imperative to continue and increase our efforts to describe genomic risk in and across Afric
36                                   As part of our effort to design novel inhibitors of ROCK, we invest
37 onary races of virus and antibody may impact our efforts to design a universal influenza vaccine.
38 l hierarchy of enamel and that contribute to our efforts to design and develop enamel biomimetic mate
39                               Here we report our efforts to design and discover a new series of tunab
40                                 As a part of our efforts to design prodrugs for antiviral nucleosides
41                                           In our efforts to design selective histone deactylase inhib
42                               We report here our efforts to determine direct antitumor effects of tha
43                                   As part of our efforts to determine the molecular details of the ro
44                                           In our effort to develop a pharmacotherapy for the treatmen
45                                           In our effort to develop agents for the treatment of influe
46  of the many lessons that we have learned in our effort to develop experimental treatments for Hutchi
47                                           In our effort to develop FR-targeted SMDCs with varying mec
48                                           In our effort to develop high-affinity ligands for the dopa
49                                           In our effort to develop more potent, less neurotoxic agent
50                                           In our effort to develop multifunctional compounds that cot
51                                           In our effort to develop multifunctional drugs against Park
52                                           In our effort to develop selective sphingosine kinase-2 (Sp
53                             Herein we report our efforts to develop a continuous flow methodology for
54                                           In our efforts to develop a disease-modifying osteoarthriti
55 nefits of increasing body coverage, describe our efforts to develop a first-generation total-body PET
56 xt of a PRMT5 inhibitor program, we describe our efforts to develop a flexible and robust strategy to
57                   We have been successful in our efforts to develop a long lived noncytolytic murine
58                            Here, we describe our efforts to develop a selective SRC covalent inhibito
59 chemical and biophysical assays, we describe our efforts to develop acyclic scaffold-hops from GSK-69
60 ploration of therapeutic options, we focused our efforts to develop an Ex Vivo Tumor platform to cult
61  investigate these mechanisms, specifically, our efforts to develop and validate aptamers containing
62 ent that could actually mislead or misdirect our efforts to develop better diagnostic tools and more
63                                   As part of our efforts to develop CB2 PET imaging agents, we invest
64 ypes that comprise the nervous system and in our efforts to develop cellular models of disease that r
65 s combination and discuss its importance for our efforts to develop climate change-resilient crops.
66 ns underlying neurodegeneration will enhance our efforts to develop effective therapeutic approaches
67                                   As part of our efforts to develop effective WNV inhibitors, we reex
68               These explorations will inform our efforts to develop highly effective and robust organ
69                         Herein, we report on our efforts to develop in vitro assays to reliably ident
70             In this study, we have continued our efforts to develop isoxazole-based anti-TB compounds
71 rd for future immunotherapies and will guide our efforts to develop more efficacious and less toxic i
72                                   As part of our efforts to develop nanoparticles with novel optical
73                Since then, we have continued our efforts to develop new and improved database tools t
74                              Here, we detail our efforts to develop noncovalent, macrocyclic peptide
75 e recently reported a preliminary account of our efforts to develop novel diarylamine radical-trappin
76 e recently reported a preliminary account of our efforts to develop novel diarylamine radical-trappin
77                                           In our efforts to develop novel nNOS inhibitors for the tre
78                                           In our efforts to develop novel small molecule NLRP3 inhibi
79                                           In our efforts to develop oncolytic peptides, we identified
80                                           In our efforts to develop orally active GPIIb-IIIa antagoni
81                                   As part of our efforts to develop peptide-based hydrogel materials
82                                           In our efforts to develop photoswitchable antibiotics, we i
83                                           In our efforts to develop potent and selective antagonists
84                                   As part of our efforts to develop rhenium-oxo corroles as photosens
85  bioisosteres represent an important step in our efforts to develop stable, bioavailable, and selecti
86                                   As part of our efforts to develop synthetic access to this family,
87                  In this study, we continued our efforts to develop triazol-4-ylphenyl bearing hydrox
88                           Here, we summarize our efforts to devise and employ diverse imaging tools t
89                                           In our effort to discover DPP-4 inhibitors with added benef
90                                           In our effort to discover potent and specific inhibitors of
91                            Here, we describe our efforts to discover a novel series of selective PI3K
92                         As a continuation of our efforts to discover and develop the apoptosis-induci
93                          Herein, we describe our efforts to discover highly potent, partial agonists
94                                           In our efforts to discover neuronal isoform selective nitri
95                                           In our efforts to discover novel and truly selective nAChR
96                               As a result of our efforts to discover novel p53:MDM2 protein-protein i
97                             Here we describe our efforts to discover novel, highly potent inhaled inh
98                             In the course of our efforts to discover potent inhibitors of Bcl-2 famil
99                                              Our efforts to discover potent, orally bioavailable type
100                                   As part of our effort to dissect the mechanism(s) underlying induct
101  results place the mosquito at the centre of our efforts to dissect mechanisms of protective immunity
102                               Here we extend our efforts to dissect the mechanism of inhibition and s
103 rofession to regulate its own practices, but our efforts to do so have been uneven.
104 ubjects generate such antibodies will assist our efforts to elicit bNAbs by immunization.
105  in the Escherichia coli system has hindered our efforts to elucidate its structure and function.
106                                              Our efforts to elucidate potential mechanism(s) for this
107                                           In our efforts to elucidate the interaction between Cdc25B
108                           Herein we describe our efforts to elucidate the key mechanistic aspects of
109                Here we report the results of our efforts to elucidate the mechanism of regulation of
110                                              Our efforts to elucidate the molecular events in the ear
111                                    We report our efforts to enable transition-metal catalysis in the
112 lly consider the method of administration in our efforts to engage specific central oxytocinergic tar
113    To address these challenges, we report on our efforts to engineer a (monovalent) single-chain dime
114 tively predicting biological behavior hinder our efforts to engineer biological systems to produce bi
115                    In this work, we describe our efforts to engineer complex riboswitches capable of
116 the temperate Burkholderia phage Milagro and our efforts to engineer this phage into a potential ther
117                                           In our effort to enhance its solubility by using natural me
118                            Herein, we report our efforts to enhance the pharmacological profile of ou
119                                   As part of our efforts to evaluate the role of sialic acid in the p
120                   This requirement catalyzed our efforts to evolve MS-grade mutant PTM-directed prote
121                                   As part of our efforts to expand the genetic alphabet, we have deve
122                                           In our efforts to expand this small family of phases, LaScS
123                                           In our effort to explain this effect, we have begun to meas
124                                              Our efforts to explain this unexpected result led to the
125                                           In our efforts to explore marine cyanobacteria as a source
126                                           In our efforts to explore the biology of the male reproduct
127 ths, metastasis is the ultimate challenge in our effort to fight cancer as a life-threatening disease
128                                           In our effort to find diagnostic markers and to develop the
129                                           In our effort to find small-molecule treatments of advanced
130                           In continuation of our efforts to find highly potent activators of PKC for
131 ed understanding of voluntarism will help in our efforts to fulfill the principle of respect for pers
132                             Here we describe our efforts to fully characterize the cellular localizat
133                                           In our efforts to further characterize this unusual mode of
134                                           In our efforts to further explore their antiviral activitie
135                                           In our efforts to further explore this direction, we have u
136                         This article reports our efforts to further improve a single-method fold reco
137                                           In our efforts to further optimize the compound class, we h
138                      In this paper we report our efforts to further optimize the selectivity profile
139                            Herein, we report our efforts to further understanding of the functions th
140                            Here we summarize our efforts to further validate ChoKalpha as an oncogeni
141                                           In our effort to gain further insight into the enantioselec
142                    These models form part of our effort to generate an anatomic framework of Drosophi
143                                   As part of our effort to generate better analogs of rifamycin, we s
144                   In this work, we continued our effort to generate new, potent, nontoxic, and multip
145                                           In our efforts to generate a new medicine for liver fibrosi
146 ibrosis, and that FZHY treatment can enhance our efforts to generate mature hepatocytes with prolifer
147 an endanger the individual, our society, and our efforts to handle the disease.
148  most of the major treatment modalities, yet our efforts to harness this knowledge to improve therape
149 ormation-related Ag, which was the result of our effort to identify an antigenically distinct tumor A
150                                           In our effort to identify CRF(1) antagonists with improved
151                                           In our effort to identify G protein coupling domains of the
152                                           In our effort to identify inhibitors of the HIF-1 activatio
153                                              Our effort to identify novel drug-resistant genes in cyc
154                                           In our effort to identify structural and functional homolog
155                         This report outlines our efforts to identify a compound suitable for once dai
156                                           In our efforts to identify a myeloid tumor suppressor gene
157                            Herein, we report our efforts to identify a novel chemotype as one strateg
158                             Here we describe our efforts to identify a potent, selective, and G prote
159                           We describe herein our efforts to identify a selective neutral endopeptidas
160                                              Our efforts to identify additional endogenous direct tar
161                   In this paper, we describe our efforts to identify an additional interaction and a
162                                           In our efforts to identify cellular DNA repair proteins req
163            Herein we describe in more detail our efforts to identify FB inhibitors by high-throughput
164                                           In our efforts to identify genes that participate in this p
165                                           In our efforts to identify IFN-induced cellular proteins th
166 ge of an opportune byproduct obtained during our efforts to identify IRAK4 inhibitors, we identified
167                                           In our efforts to identify molecules that might act as coca
168                                           In our efforts to identify novel chemical scaffolds for the
169                                           In our efforts to identify novel chemical scaffolds for the
170                                           In our efforts to identify novel galectin-3 disaccharide mi
171                                              Our efforts to identify novel Na(+),K(+)-ATPase binding
172                             Here we describe our efforts to identify novel proteins using a phage-dis
173                                           In our efforts to identify novel small molecule inhibitors
174                    Subsequently, we extended our efforts to identify PI3Kalpha-specific inhibitors us
175                                              Our efforts to identify potent, efficacious, and orally
176                                              Our efforts to identify potent, selective FabI inhibitor
177                          Herein, we disclose our efforts to identify potent, selective, and orally bi
178                                              Our efforts to identify potent, selective, and pharmaceu
179                          Herein, we describe our efforts to identify reversible inhibitors of LSD1 fr
180                                In continuing our efforts to identify small molecules able to disrupt
181                         Although successful, our efforts to identify superior combinations of growth-
182             In the current study, we focused our efforts to identify the BMD candidate gene in chromo
183 dient dialysis has allowed a breakthrough in our efforts to identify the nucleosomal locations of the
184                                           In our efforts to identify the protein components of the ce
185                                           In our efforts to identify the residue at which this radica
186                            Herein, we report our efforts to identify the steric and leaving group req
187  lack of molecular understanding complicates our efforts to identify therapeutic compounds or strateg
188      It is of vital importance that we renew our efforts to identify, evaluate and treat all patients
189 mapping study has been unexplored, hampering our effort to illustrate the detailed genetic architectu
190         As cardiologists, we should increase our efforts to improve coverage, quality, and cost, both
191     How can we maximize the present value of our efforts to improve diagnostic imaging?
192 r understanding of human biology and advance our efforts to improve health.
193                        Here, we will discuss our efforts to improve the clinical care of patients wit
194             Here we report on the results of our efforts to improve the MWM method's predictive accur
195                            We also report on our efforts to improve the oral bioavailability and phar
196             In the present work, we describe our efforts to improve the performance of one of the ear
197                             We report herein our efforts to improve their pharmacokinetic properties
198                                We now report our efforts to improve this vaccine by screening a subli
199                          Herein, we describe our efforts to inhibit the essential A. baumannii lipool
200                                   As part of our effort to investigate the structure-transfection eff
201                                           In our efforts to investigate the role of the cytoplasmic D
202                             This has focused our efforts to isolate genes required for newborn respir
203  immunosuppressive drugs; and (iii) describe our efforts to make new less-immunogenic RITs by identif
204       In this paper we report the results of our efforts to map the genes responsible for resistance
205                               We report here our efforts to measure the crawling force generated by c
206 sses by which N2O is produced is critical to our efforts to mitigate climate change.
207  sources, which can result in biases-despite our efforts to mitigate them-related to the methodologic
208                             Here we describe our efforts to more precisely define the role of sbyA an
209                                           In our effort to obtain a thorough genotype, we have analyz
210                                           In our efforts to obtain atomic information on microtubule-
211                                           In our efforts to obtain electrocatalysts with improved act
212                                   As part of our effort to optimize conditions for evaluating VR1 pha
213                           In continuation of our effort to optimize the pharmacological profile of [1
214                            Here, we describe our efforts to optimize 1.
215 ent success in this area, we describe herein our efforts to optimize a novel purine carboxylic acid-d
216                                We now report our efforts to optimize quinolon-4(1H)-imines as dual-st
217  agonists is described herein as we continue our efforts to optimize the 2-phenylcyclopropylmethylami
218                             Herein we report our efforts to optimize the MMP-13 potency and pharmacok
219     In the work described here, we report on our efforts to optimize the sensitivity of SUPREX analys
220                             Here we describe our effort to overcome this limitation, the PSC-SCR, a r
221            It is imperative that we increase our efforts to prepare for the unique challenges that we
222                            Herein, we detail our efforts to prepare these molecules by chemical synth
223                              Herein, we make our efforts to present a comprehensive review on the lat
224                                           In our efforts to produce monoclonal antibodies that recogn
225                                   As part of our efforts to produce neuroprosthetic devices and to fu
226                                           In our efforts to protect patient privacy, however, we shou
227 he data represent an important first step in our efforts to provide genetically improved crickets for
228                                 As a part of our efforts to pursue direct, convergent, and concise me
229  selectivity remains limited, thus hindering our efforts to rationally re-engineer PKSs.
230             It is thus essential to redouble our efforts to reach the goal of placing 15 million peop
231                                              Our efforts to reconstitute pitcher fluid activity using
232 ng, and after endosymbioses further confound our efforts to reconstruct the ancient mergers that forg
233                  Therefore, we here describe our efforts to reconstruct the phylogeny of all availabl
234 comprehensive genomic resources and describe our efforts to reduce genome redundancy in our Bacteria
235 nd worldwide rapid transportation complicate our efforts to reduce the impact of LRI disease in child
236                                   As part of our efforts to relate anti-DNA affinity and specificity
237                                     However, our efforts to replicate this experiment were confounded
238 more, we will describe how we have increased our efforts to reuse, reanalyze and disseminate high-qua
239                                              Our efforts to reveal how Cobl is physically and functio
240  state of the 3D chromatin field and discuss our efforts to run and validate the models.
241                                           In our efforts to scan the mRNA-displayed proteome librarie
242                     [reactions: see text] In our effort to search for carbonyl reductases with anti-P
243                                           In our effort to search for key regulators in the plant vac
244                             Here, we discuss our efforts to simplify the bicyclohexane fused thiophen
245 tion of multivalent compounds is critical to our efforts to study and interface with biological syste
246                                    We report our efforts to study host-guest complexes in the gas pha
247 , we generated mt-Keima Drosophila to extend our efforts to study mitophagy in vivo.
248                            Here, we describe our efforts to study TCDS in E.coli using a newly develo
249                                           In our efforts to study the binding of the beta(')-subunit
250                                       During our efforts to study this pathway, we identified HBD2 (h
251                                              Our efforts to suppress TNF-alpha have centered on the i
252                              Here, we report our efforts to tap the potential of understudied GPCRs b
253                         During the course of our efforts to target intracellular protein-protein inte
254                                   As part of our efforts to target the 5-HT6 receptor, new benzimidaz
255                 The present study is part of our effort to test the hypothesis that each glomerulus i
256 efficiencies of nuclear transfer we directed our efforts to the introduction of specific genetic chan
257                         We recently reported our efforts to tune the selectivity of these inhibitors
258                                           In our efforts to uncover the metabolic pathways that contr
259                                           In our efforts to uncover trade routes of trafficked sea tu
260                                           In our effort to understand genetic disorders of the photor
261                                   As part of our effort to understand how Elongin C regulates the act
262                                   As part of our effort to understand how the Elongin BC complex regu
263   Network analysis has an increasing role in our effort to understand the complexity of biological sy
264                                   As part of our effort to understand the functions of Elongin BC-bas
265                                   As part of our effort to understand the molecular and physiological
266                                           In our effort to understand the molecular basis of this int
267  single P-element insertions will facilitate our effort to understand the structural and functional p
268                      Here, we briefly review our effort to understand the structural organization of
269                                           In our effort to understand the transcriptional regulation
270 man age-related nondisjunction, complicating our efforts to understand - and, ultimately, to provide
271      In the current paper, we wish to report our efforts to understand and improve the poor PK in non
272                This insight is invaluable to our efforts to understand and subsequently design sequen
273 ic behavior in silico is an integral part of our efforts to understand biology.
274 ein profiling) has become a key component in our efforts to understand complex biological processes.
275 eritance are an emerging area of interest in our efforts to understand fetal alcohol spectrum disorde
276                          Herein, we describe our efforts to understand how to co-optimize human and m
277             Like the immune response itself, our efforts to understand the "rules" for self-nonself d
278                                           In our efforts to understand the consequences of replacing
279 s paper represents the latest development in our efforts to understand the Earth's biodiversity at th
280                                              Our efforts to understand the function of sensory system
281              This study is a continuation of our efforts to understand the interplay in the self-asse
282                                  We describe our efforts to understand the key mechanistic aspects of
283                                           In our efforts to understand the mechanism of a drug-resist
284                                           In our efforts to understand the molecular genetic basis of
285                                           In our efforts to understand the physiology of recovery, we
286                                           In our efforts to understand the role of gamma-tubulin in c
287                                           In our efforts to understand the role of pathway in affecti
288 ilic airway inflammation in a mouse model in our efforts to understand the underlying mechanisms.
289 ailable data suggest that we should increase our efforts to understand the virology and pathogenesis
290                                           In our efforts to understand their synthesis, chemical comp
291                                              Our efforts to understand why DinB (DNA polymerase IV) o
292  widespread devastation, we need to increase our efforts to understanding the physiological and metab
293                        As an initial step in our efforts to unify the expression of peptide retention
294 most cell types, it would greatly facilitate our effort to unravel transcriptional regulatory network
295                          This study presents our efforts to unravel the complexity of the interactome
296                            Here, we describe our efforts to use artificial intelligence (AI)-based im
297                                   As part of our efforts to use NMR techniques to assist in decipheri
298 he study presented here is a continuation of our efforts to use the X-ray structure of the T. foetus
299       The current study is a continuation of our efforts to use the X-ray structures of T. brucei and
300                             We also describe our efforts to validate GeneScription through its evalua

 
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