ライフサイエンスコーパス: overcome

1 social obstacles to male provisioning can be overcome.

2 stical and technical challenges that must be overcome.

3 fector T cells and how this imbalance can be overcome.

4 , square roots are the gravest challenges to overcome.

5 The inherent challenge for CS is to overcome 4 to 6 log-folds stronger affinity for its natu

6 rget molecules for therapeutic strategies to overcome 5-FU resistance.

7 cribed, along with optimization efforts that overcame a configurational stability issue arising from

8 When cells progress to malignancy, they must overcome a final telomere-mediated proliferative lifespa

9 unlikely as the migratory insertion needs to overcome a prohibitively high energy barrier.

10 and green color channels of phone images to overcome a strong evaporation-induced optical artifact i

11 egy for large-scale ivermectin treatment and overcomes a major obstacle to the elimination of onchoce

12 tains a domain that interacts with UNC79 and overcomes a soma-retention signal to achieve dendritic l

13 mino acid distribution in membrane proteins, overcoming a critical flaw in previous membrane models t

14 rmation on the pregnane X receptor helped in overcoming a persistent cytochrome P450 3A4 induction pr

15 At the same time, ambient temperatures help overcome activation barriers that impede diffusion and r

16 abrication and implementation in devices are overcome, adaptive molecular crystals can have far-reach

17 ual environments is a promising candidate to overcome ADHD related memory problems.

18 lerated, and OPT-302 combination therapy may overcome an escape mechanism to VEGF-A suppression in th

19 ever, with Ag overexpression, this defect is overcome, and low-avidity T cells control tumor growth.

20 ng research and clinical care, hurdles to be overcome, and the need for multidisciplinary collaborati

21 embrace telehealth and develop strategies to overcome associated challenges.

22 By contrast, race SG4z overcomes B301 resistance and successfully parasitises t

23 have developed equally diverse mechanisms to overcome bacterial Abi.

24 segment in avian influenza virus (AIV) could overcome barriers to cross-species transmission.

25 This information will inform ways to overcome barriers to reporting sexual harassment.

26 Whether SecA generates mechanical force to overcome barriers to translocation posed by structured s

27 Overcoming barriers to universal sanitation coverage and

28 as towards the alternative action, which was overcome before progressing towards action initiation.

29 challenges that this technology still has to overcome before reaching the market, and future perspect

30 rticle-based drug delivery system capable of overcoming biological barriers and leveraging on several

31 O(2) (NCM) || Li batteries that are able to overcome both challenges.

32 a conceptually elegant approach to not only overcome, but better yet, exploit intra-tumoural hypoxia

33 This has been overcome by comparing historic plankton tows from the se

34 pand during viral infection, and this can be overcome by exogenous IL-2 administration.

35 In this work, this stochasticity is overcome by incorporating a solid electrolyte interlayer

36 kely via an allosteric mechanism that can be overcome by increasing RET ligand concentration.

37 F2-mutated HCC and if this resistance can be overcome by means of NRF2 inhibition in HCC cell lines.

38 enhancers at multiple loci can be partially overcome by reducing activity of the chromatin regulator

39 etic kinase inhibitors, an issue that may be overcome by targeting unique residues or binding pockets

40 Although the block imparted by Tbf1 can be overcome by the DNA-binding activity of the single-stran

41 ance mutations within each binding site were overcome by the inhibition of the opposite functional an

42 The problem of low Raman scattering was overcome by trapping particles with 2D optical tweezers.

43 ith altered epigenetic landscapes and can be overcome by wild introgression.

44 Understanding how plants grow and overcome challenges to their survival is critical for us

45 ination of a CHK1i plus a WEE1 inhibitor can overcome CHK1i resistance of these tumor cells, thereby

46 tipping point where gains from provisioning overcome costs from paternity uncertainty and the dad st

47 on, allows adsorbent design trade-offs to be overcome, coupling low heat of adsorption (-10 to -17 kJ

48 d is concretely able to design products that overcome critical barriers in conventional medicine in a

49 wnstream of AR could be a viable strategy to overcome CRPC.

50 cts, beam shaping and multivariate analysis, overcomes current limitations of plasmonic detection sys

51 r clinical trials testing rational agents to overcome de novo enzalutamide resistance.

52 xpression of the nucleocapsid component VP35 overcomes deletion of NP-Ct in triggering IB formation,

53 a syntrophic relationship is established to overcome detrimental host diets and identify Ap as the b

54 minimize epigenetic fluctuation, potentially overcoming differences in PSC line differentiation poten

55 In interphase, TRAIP helps replisomes overcome DNA interstrand crosslinks and DNA-protein cros

56 ined inhibition of both EGFR and STAT3 might overcome drug resistance encountered during treatment wi

57 meet its potential to accelerate resistance-overcoming drug combination discovery.

58 n and immunotherapeutic strategy designed to overcome each step of the cancer-immunity cycle and prop

59 he integrity of the mitochondrial network to overcome environmental insults and respond to physiologi

60 ctors such as CHPT1 can be viable targets to overcome Enz resistance in PCa.

61 PAWI-2 also overcame erlotinib (an EGFR inhibitor) resistance in FGb

62 ndscape and epigenetic barriers that must be overcome for cardiac regeneration to occur.

63 asses of nucleic acids, hurdles that must be overcome for effective intracellular delivery, types of

64 idering the energy barrier a filament has to overcome for joining a bundle.

65 However, several challenges have to be overcome for this concept to become a practical way to e

66 broad spectrum of posttraumatic sequelae (to overcome fragmentation) and also perform in-depth biobeh

67 gic mediators or suppressors can allow us to overcome GBM regrowth in the context of tumor heterogene

68 expression of dapF(Ct) allowed the mutant to overcome growth inhibition.

69 This review explains solutions to overcome heterogeneity in routine data such as the use o

70 ocus on advances in nanoparticle design that overcome heterogeneous barriers to delivery, arguing tha

71 Our approach overcomes high control mortality seen in other bioassay

72 ins involved in flagella structure/output to overcome higher viscosity, flagella rotation to accumula

73 o-opt a cellular ubiquitin ligase complex to overcome host defences and promote virus production.

74 hogenic bacteria depends on their ability to overcome host nutritional defenses and acquire nutrients

75 st example of an ECF-transporter involved in overcoming host-induced nutritional limitation.

76 tumors requires combinatorial strategies to overcome immune suppression associated with the tumor mi

77 ung and pancreas and potential approaches to overcome immunoresistance in the latter.

78 This weakness is overcome in modern biological systems by kinetic control

79 s capable of sustaining repetitive activity, overcoming inhibitory mechanisms that restrict excitator

80 To overcome intrinsic drawbacks in specificity, sensitivity

81 One obstacle to overcome is the amount of data needed by learning system

82 One such barrier, whose mechanism for overcoming is poorly understood, is access to recombinat

83 ory feedback mechanism in which ectopic PHF7 overcomes its own transcriptional repression through pro

84 d oxygen level-dependent (BOLD) MRI approach overcame key limitations associated with conventional ca

85 We aimed to overcome limitations of previously conducted coffee tria

86 p learning-assisted analytical approaches to overcome longstanding challenges in natural products dru

87 d and paper formats into hybrid devices that overcome many of these limitations, while capitalizing o

88 Our approach overcomes many of the historical challenges with measure

89 e iterative nature of the procedure helps to overcome masking effect in outliers, and a backward step

90 Current clinical treatments to overcome MDR involve the co-delivery of a Pgp inhibitor

91 model, neutralization of dicarbonyl activity overcame MDSC-mediated T cell suppression and, together

92 CD133 signal to PI3K pathway is essential to overcome Melanoma resistance to fotemustine.

93 nnected to a mobile APP) with functions that overcome most of the EAI limitations and to determine wh

94 ons, less integrated individuals more likely overcame neophobia (as compared to more integrated ones)

95 While many bacterial mechanisms for overcoming nutritional immunity have been identified, th

96 the hypothesis that alpha power reflects the overcoming of an idiosyncratic bias.

97 eatment approaches and suggest strategies to overcome or prevent osimertinib resistance in vivo.

98 ratumoral injection with the oncolytic virus overcomes PD-L1-mediated immunosuppression during both t

99 mmonly use molar phosphate concentrations to overcome phosphate's poor reactivity with organics in wa

100 However, success will depend upon overcoming political and social inertia to develop regul

101 Further research is needed to overcome potential restrictions for IVT in patients taki

102 ools, we demonstrated that FACT is needed to overcome replication stress.

103 SOC-PDX with reduced sensitivity to PARPi by overcoming replication fork protection.

104 Influential physicians willing to overcome resistance to advances were able to bring medic

105 lternative or combined strategies that might overcome resistance to RTK inhibitors in patients with c

106 resistance and persistent vulnerabilities to overcome resistance.

107 fication of clinically viable strategies for overcoming resistance to platinum chemotherapy in lung a

108 nt of drug-resistant tumors and a target for overcoming resistance.

109 AC-driven electroluminescent devices can overcome several limitations of conventional DC-driven e

110 Surface heating membrane distillation overcomes several limitations inherent in conventional m

111 This method overcomes several major technical challenges that have p

112 retation, and clinical use of HMSAs requires overcoming several computational, statistical and engine

113 ecent decades, researchers have attempted to overcome shortcomings in CIs by improving implant techno

114 value; however, complementary strategies to overcome social and structural barriers to HIV care will

115 root growth results from forces required to overcome soil resistance to deformation.

116 The use of this line will help to overcome some of the existing limitations in the study o

117 ic Environmental Sample Processor (ESP) that overcomes some of the constraints associated with tradit

118 ty of resident cells within the wound bed to overcome stalled wound healing.

119 mine biosynthesis to the methionine cycle to overcome stress.

120 This AI system overcomes substantial interobserver variability in exper

121 Our approach overcame the challenge of time- and labor-consuming biol

122 evealed that inhibition of MEK/ERK signaling overcame the HIF1a-mediated block in oligodendrocyte gen

123 This allows us to overcome the "blind sphere" in paramagnetic proteins, an

124 breadth may supplant depth of sequencing to overcome the barrier of cfDNA abundance.

125 n-specific cell-cell adhesion to effectively overcome the barrier to T6SS activity in fluid condition

126 other disciplines will gradually allow us to overcome the barriers identified on the demanding path t

127 with percutaneous coronary intervention may overcome the barriers to utilization.

128 To overcome the challenge posed by low frequency of the AA

129 reconsideration of engineering strategies to overcome the coercivity limits.

130 on 3 of the CoGAPS R/Bioconductor package to overcome the computational limitations of Bayesian matri

131 se antibacterial resin adhesives ingeniously overcome the defect of the present materials and hold gr

132 works are generated in a gelatin hydrogel to overcome the diffusion limit of nutrients and oxygen thr

133 ive for the study of 3D printer emissions to overcome the disadvantages in chamber methods and as a m

134 py of miR122, and 24 copies of Paclitaxel to overcome the drug effluxion and chemoresistance thus, sy

135 an initial framework for creating avenues to overcome the drug resistance of ferroptosis activators.

136 neer systems capable of delivering oxygen to overcome the effects of both systemic and local hypoxia

137 studies suggest that AMT-101 can efficiently overcome the epithelial barrier to focus biologically ac

138 y, and preventing Thr241 phosphorylation can overcome the H(2)O(2) sensitivity of Tsa1-deficient cell

139 tivating expression of anti-PD-L1-gamma1 can overcome the immunosuppressive environment in MMC tumors

140 establish protocols specifically designed to overcome the inevitable variations in sample quality res

141 We employ a dextran polymer particle to overcome the inherent lipophilicity of VSDs by dynamic e

142 drug delivery systems have the potential to overcome the issues facing immediate-release and first-o

143 To overcome the kinetic inertness, an unsubstituted aminoox

144 R pathway in IDO/TDO expressing tumors would overcome the limitation of single IDO or TDO targeting a

145 Various signal amplification methods can overcome the limitation of SPR methods for detection of

146 There has been an ongoing effort to overcome the limitations associated with the stability o

147 e intervention could prevent new infections, overcome the limitations of antiretroviral treatment, co

148 correlate with histology and may be used to overcome the limitations of conventional bread-loaf hist

149 Mass spectrometry (MS)-based methods could overcome the limitations of current detection techniques

150 Nanoparticles have been developed to overcome the limitations of free therapeutics and naviga

151 on have been extensively studied in order to overcome the limitations of homogeneous Fenton processes

152 This provides opportunities to overcome the limitations of introducing modifying nucleo

153 To overcome the limitations of single-model approaches, CoM

154 direct oral anticoagulant with potential to overcome the limitations of standard of care in children

155 In order to overcome the limitations of the mutant DISC1 model and u

156 ailing coupled with electronic messaging may overcome the limitations of the prior interventions.

157 develop a slow sustained-release strategy to overcome the limited dispersibility of protein in the et

158 ed to determine whether such approaches will overcome the limited efficacy of tocilizumab observed in

159 tly generated images of sub-voxel components overcome the limited spatial resolution of MRI, thus adv

160 demand for data communication bandwidth and overcome the limits of electrical interconnects, silicon

161 ors, and ICU staff must devise strategies to overcome the modifiable determinants of adverse mental i

162 ing constitutively active MALT1 mutants that overcome the need for monoubiquitination, we reveal an a

163 all fraction of disseminated tumor cells can overcome the numerous hurdles they encounter during the

164 ough thermal post-treatment are essential to overcome the obstacle of morphology/structure inconsiste

165 rs have recently created knockin models that overcome the overexpression problem, and have generated

166 c light-emitting diode displays, and also to overcome the performance and reliability issues of a-Si:

167 nstrate capabilities, the system was used to overcome the Poisson loading problem by sorting for drop

168 To overcome the present limits, we propose a future configu

169 nsporter, CycA, was sufficient to completely overcome the repression of type 3 secretion system activ

170 ur knowledge, fluorescence-based assays that overcome the restrictions imposed by the NE environment.

171 for patient stratification in an attempt to overcome the series of failures that has characterised d

172 methodology, called selective alignment, to overcome the shortcomings of lightweight approaches with

173 ucts encoded in foreign genes, bacteria must overcome the silencing effects of H-NS.

174 compact Type II-C Cas9 orthologs can help to overcome the size limitation of SpCas9.

175 However, to overcome the sparsity of FRET experiments, they need to

176 well as other PI3K pathway inhibitors, could overcome the therapeutic limitations associated with sin

177 To overcome the three delays in triage, transport and treat

178 harge displacement required for the motor to overcome the viscous cochlear load.

179 SIMMS(2) thus overcomes the bottleneck for decoding the informational

180 approach of learning discrete field theories overcomes the difficulties associated with learning cont

181 The approach reported here effectively overcomes the difficulties that are commonly encountered

182 Two-photon excitation (TPE)-based imaging overcomes the filtering of ultraviolet light by the lens

183 osite oxoA, suggesting the nascent oxoA:dGTP overcomes the geometric discrimination of poleta.

184 potent progenitors in the bone marrow, which overcomes the immunosuppressive tumor microenvironment.

185 om multiple methods of driver discovery that overcomes the limitations of individual methods.

186 8 overcomes the metabolic liabilities of PQR620 (52), the

187 coplanar Coulter counter device design that overcomes the problem of constriction clogging while cap

188 ammary duct after intraductal administration overcomes the rapid ductal clearance of CPX, prolongs ma

189 tage of dimensionality, we show that AR-RBFN overcomes the shortcomings of noisy and short time-serie

190 s demonstrating that the microwire biosensor overcomes the time limitation of permanently implanted b

191 These considerations include overcoming the barriers presented by opportunity costs,

192 cient technically - and make suggestions for overcoming the classical opposition between the cultural

193 ted intratumoral CD8(+) T-cell infiltration, overcoming the exclusion effect; TGFbeta1 inhibition cou

194 with the hypoglycemic event in each subject, overcoming the intelligibility problem of deep-learning

195 l and/or immune histochemical investigation, overcoming the limitation of field studies, where optima

196 yer at the perovskite/HTM interface helps in overcoming the moisture degradation of the hygroscopic p

197 networks as a replacement to ITO, they must overcome their inherent stability issues while maintaini

198 future use of live imaging technologies and overcoming their current limitations is provided.

199 cal understanding and future requirements to overcome them.

200 sue-specific drug delivery and strategies to overcome them.

201 dles in the field, as well as priorities for overcoming them.

202 nts and their functional validation may help overcome these caveats allowing for a greater number of

203 We discuss recent efforts to overcome these challenges and innovative means to reduce

204 Herein, we overcome these challenges by introducing a simple and pr

205 H oxidation directed by carboxylic acids can overcome these challenges to yield gamma-lactones in hig

206 ent stem cells (iPSCs) have the potential to overcome these challenges, due to their capacity for mul

207 To overcome these challenges, we employ a rigid planar liga

208 ies coalescent (MSC) methods can potentially overcome these challenges.

209 In order to overcome these difficulties, we present here a sophistic

210 To overcome these difficulties, we propose DR-A (Dimensiona

211 Scanning near-field optical microscopy can overcome these issues and can characterize waveguide mod

212 bulk heterojunction (BHJ) has significantly overcome these issues, resulting in dramatic improvement

213 To overcome these issues, we moved the cantilever in a sawt

214 To overcome these issues, we propose a novel approach that

215 ating agents or highly branched polymers may overcome these issues.

216 nomedicine approaches have been developed to overcome these issues.

217 sed HIV-1 infection, we tested strategies to overcome these limitations and challenges.

218 To overcome these limitations and facilitate the investigat

219 To overcome these limitations and to cope with the demand f

220 elope subunit antigens have the potential to overcome these limitations but have historically perform

221 nt-addressable memory concept and circuit to overcome these limitations by utilizing the analog condu

222 One strategy used to overcome these limitations is the decoration of the oute

223 To overcome these limitations we use the growth of plankton

224 To overcome these limitations, a generic and fast achiral-c

225 optic-surface plasmon resonance (FO-SPR) can overcome these limitations, but improved surface chemist

226 To overcome these limitations, we designed new rhesus-speci

227 To overcome these limitations, we have developed CRISPRitz,

228 To overcome these limitations, we used a hypothesis-driven

229 Here, we present new tools to overcome these limitations.

230 In this work, we overcome these practical and technical challenges with R

231 To overcome these problems, we developed a method that does

232 der range of cell culture systems might help overcome these shortcomings.

233 overproduction of pro-angiogenic ligands can overcome these therapies, hampering success of this appr

234 To overcome these, we propose a unique low cost device as a

235 first-row transition-metal fluorides, and it overcomes these limitations.

236 roughput prokaryotic scRNA-seq pipeline that overcomes these technical obstacles.

237 ns of antitumor targeted agents may offer in overcoming these challenges and detail techniques whereb

238 In overcoming these critical knowledge gaps, integration of

239 By overcoming these experimental difficulties at least part

240 Progress in overcoming these limitations has been challenging becaus

241 Biosensors have shown a great potential in overcoming these limitations.

242 e, I review two decades of research aimed at overcoming these three difficulties.

243 We overcame this problem by recording unique tracks of gree

244 Cryo-sectioning methods employed to overcome this are technically challenging, subject to ar

245 developed liposomal spherical nucleic acids overcome this barrier and enable topical delivery of ant

246 Features at each end of the substrate overcome this barrier and promote release by stepwise ex

247 tion (SFG) spectroscopy has the potential to overcome this challenge and investigate the structure an

248 anical topological insulators have sought to overcome this challenge by supporting back-scattering re

249 One promising way to overcome this challenge is to have low-energy photons re

250 Several strategies have been proposed to overcome this challenge, including insecticides with new

251 To overcome this challenge, we developed marginal path like

252 Here, to overcome this challenge, we present a video-based deep l

253 To overcome this challenge, we traced isotope-labeled nutri

254 In attempt to overcome this defect, we generated mice overexpressing i

255 To overcome this deficiency, we have previously employed co

256 itional therapeutic modalities are needed to overcome this deficiency.

257 We overcome this difficulty by utilizing indium as a metal

258 We have now overcome this dilemma by using a multipronged approach:

259 -XTEN) is a novel fusion protein designed to overcome this half-life ceiling and maintain high sustai

260 (air) core fibres offers a potential way to overcome this insurmountable attenuation limit set by th

261 To overcome this issue, we developed a mass spectrometry-ba

262 To overcome this issue, we postulated that some level of ir

263 To overcome this issue, we propose, for the first time, the

264 oral-inspired light management systems could overcome this limitation and facilitate scalable bioener

265 l 7 tesla machine learning study to date, we overcome this limitation by capitalizing on the spatial

266 Dual-energy CT may overcome this limitation by improving the conspicuity of

267 To overcome this limitation, here we report an improved SPS

268 To overcome this limitation, we developed a hybrid data-dri

269 To overcome this limitation, we developed a new version of

270 To overcome this limitation, we devised cell models in whic

271 To overcome this limitation, we have developed a methodolog

272 To overcome this logistical challenge, we propose a new par

273 To overcome this problem, we developed a checklist and guid

274 To overcome this problem, we have developed an automated an

275 ting longitudinal gradients in diversity can overcome this problem.

276 of the PB2 subunit, enable avian FluPolA to overcome this restriction and efficiently replicate vira

277 tween male provisioning and female choice to overcome this social dilemma.

278 To overcome this therapeutic barrier, we developed polymeri

279 To overcome this, we developed a series of protease-selecti

280 To overcome this, we introduce here a selective Halpha,Calp

281 ode Assisted Iron Electrocoagulation (ACAIE) overcomes this limitation by cathodically generating H(2

282 bon paper electrodes is one strategy towards overcoming this challenge, with partial relief aggregati

283 Here, we overcome those functionalization barriers through compos

284 tory to translation of Task3 in vitro and is overcome through activity of a G4-specific helicase DHX3

285 ers without other equilibrium by-products is overcome through self-sorting favored by the introductio

286 nal solution to the formidable challenges of overcoming TKI resistance and treating the TKI-resistant

287 bia) help identify the barriers that must be overcome to engineer a bacterium to deliver a high nitro

288 cate that MARCKS ED peptide therapeutics may overcome traditional GBM resistance mechanisms, supporti

289 L-induced apoptosis, and current attempts to overcome TRAIL resistance, and we provide a perspective

290 SHP2 may serve as a therapeutic strategy to overcome tumor resistance to osimertinib.

291 offers insights into possible strategies to overcome tumor-supporting TME properties and instead har

292 ate that this novel approach has promise for overcoming two major issues in human islet transplantati

293 in evading immune surveillance; this can be overcome using PD-L1 or PD-1 immunotherapy antibodies.

294 n solid-state lithium metal batteries can be overcome using this architecture.

295 These confounds are now overcome, using phase contrast and time-lapse videograph

296 tive function is suggested by its ability to overcome VEGF antagonism.

297 Chilling requirements for overcoming winter endodormancy were strongest in Salix e

298 in individuals with low weight, which can be overcome with flat dosing.

299 This challenge could be overcome with intraoperative fluorescence imaging, which

300 schemes and inconsistency in sampling can be overcome with spatio-temporal modeling to follow species