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1 k1- / - mutants even when Fgf is transiently overexpressed.
2 mall cell lung cancer (NSCLC) where c-MAF is overexpressed.
3 cells in which m(6)A METTL3 and METTL14 are overexpressed.
4 vical adenocarcinoma, where FKBP51 is highly overexpressed.
5 me 21 genes that protect against cancer when overexpressed.
6 re crossed with Alzheimer's PS19 mice, which overexpress a tau P301S mutation and exhibit age-depende
7 ular endothelium and non-classical monocytes overexpressed a distinct chemokine axis, which may orche
9 ot only reduced in ago4-1 but also in plants overexpressing a constitutively stable version of the ox
10 tomato (Pst) DC3000, while Arabidopsis lines overexpressing a JAZ4 protein lacking the Jas domain (JA
14 vo, we generated triple transgenic mice that overexpressed alpha-syn A53T mutation in the midbrain do
15 of HRI resulted in cytotoxic accumulation of overexpressed alpha-synuclein, a protein known to aggreg
16 identified two additional genes selectively overexpressed among non-responders, IGFBP3 and IGFBP5.
18 luenced by vesicle size and cargo occupancy: overexpressing an inert cargo protein or reducing vesicl
19 lecule NUMB-interacting protein (TBC1D15) is overexpressed and contributes to p53 degradation in TICs
23 of cathepsin B, a proteolytic enzyme that is overexpressed and secreted in the tumour microenvironmen
29 lyses revealed that transgenic soybean seeds overexpressing ATP sulfurylase accumulated very low leve
31 g) mice, B cell-deficient B6.muMT mice, BAFF-overexpressing/B cell-deficient B6.BTg.muMT mice, and BA
32 evealed that Dicer was decreased in miR-200a overexpressed BC cells; this resulted in inhibition of m
33 that BC200 is a translational suppressor, we overexpressed BC200 by transfection of in vitro transcri
34 . distachyon Transgenic lines constitutively overexpressing BdRAM1 showed constitutive expression of
36 c factors, conditioned media from RAB11B-AS1-overexpressing breast cancer cells promoted tube formati
37 P1 inhibitor Verteporfin resensitized ZNF367-overexpressing breast cancer cells to anoikis and abroga
42 er healthy human MSCs could be engineered to overexpress C7 and correct RDEB in a human:murine chimer
44 s an ideal target to sensitize advanced DNA2-overexpressing cancers to current chemo- and radiotherap
46 t for antigen cross-presentation, that CD40L-overexpressing CAR T cells elicit an impaired antitumor
47 demonstrate the stimulatory effect of CD40L-overexpressing CAR T cells on innate and adaptive immune
48 lls, and provide a rationale for using CD40L-overexpressing CAR T cells to improve immunotherapy resp
49 gy is an excellent tool for the discovery of overexpressed cell surface tumour antigens and the devel
50 lective uptake can also be achieved in CA IX overexpressed cells, when cocultured with ALP overexpres
51 verexpressed cells, when cocultured with ALP overexpressed cells, where the nanoassembly presumably a
52 referentially blocked proliferation of N-Myc overexpressing cells, when glutamine levels were reduced
55 nock-out strain (DeltacfrA), and two strains overexpressing CfrA from either the constitutive P (trc)
57 y bed encountered in the tail, whereas cells overexpressing constitutively active YAP were able to tr
58 urofibrillary tangles and neurodegeneration, overexpressed CX3CL1 in both male and female mice was su
59 to demonstrate that enhanced neurogenesis by overexpressed CX3CL1 is mitigated by disruption of Smad2
61 sk-associated transcripts is predicted to be overexpressed, defined by an exon-exon splice junction b
65 indicates that, although the consequences of overexpressing efflux pumps are similar (impaired QS res
67 -lox recombination-based mosaic sectors that overexpress either EPF1 or Stomagen in Arabidopsis cotyl
70 ice with a knock-in mole CYP17A1 enhancer or overexpressing FGF9 showed phenotypes recapitulating mol
71 one and alveolar bone osteocytes in Hyp mice overexpressed fibroblast growth factor 23 (Fgf23), its e
75 neuroblastoma and revealed a differentially overexpressed gene signature in MYCN nonamplified neurob
76 tment samples demonstrates that large clones overexpress genes implicated in cytotoxicity and charact
78 it compatible with race 1 P. sojae, whereas overexpressing GmMYB29A2 rendered the susceptible Willia
79 We reveal that staphylococcal sRNA RsaD is overexpressed >20-fold in a CodY-deficient strain in thr
82 f splenocytes and serum exosomes from elafin-overexpressing HFD-treated donor mice reduced food consu
84 a model, local intramuscular delivery of CSC overexpressing HIF-1alpha (HIF-CSC) significantly improv
88 tigators to develop models of familial AD by overexpressing human genes such as those encoding amyloi
92 Anti-apoptotic Bcl-2 family proteins are overexpressed in a wide spectrum of cancers and have bec
93 sfer, wild-type and mutant SK2 channels were overexpressed in adult rat VMs, revealing serine-465 as
94 tein arginine methyltransferase-5 (PRMT5) is overexpressed in aggressive B-cell non-Hodgkin's lymphom
100 t study, we found that miR-200a was markedly overexpressed in both human BC tissues and BBN-induced m
102 e show that the removal of mucins, which are overexpressed in cancer cells, facilitates their clearan
103 1 (PARP1), which is a nuclear enzyme that is overexpressed in cancer when compared with the normal su
105 ll line panel identified the MT1E gene to be overexpressed in cells that are less sensitive to TRIP.
112 lation of the ECM gene fibulin-5, which when overexpressed in ECs ameliorates OFT morphology and func
115 (DCLK1) is a serine/threonine kinase that is overexpressed in gastrointestinal cancers, including eso
116 alpha4 (KPNA4), is exclusively amplified and overexpressed in head and neck of squamous cell carcinom
124 stochemistry revealed that OASIS protein was overexpressed in human fibrotic kidney compared with nor
125 strate that tumor-derived UBR5, an E3 ligase overexpressed in human OC associated with poor prognosis
129 sis revealed that the small GTPase, Rap1 was overexpressed in lEVs from MetS patients compared with t
130 ctivation domain-binding protein 1 (JAB1) is overexpressed in many cancers and has recently emerged a
134 receptors, part of the bombesin family, are overexpressed in many tumors, including breast and prost
135 ATPase and bromodomain factor ATAD2/ANCCA is overexpressed in many types of cancer, but how it contri
138 Focusing on C-MYC, a well-known oncoprotein overexpressed in most human cancers, we show that FBXL16
139 quinone dehydrogenase 1 (Nqo1), is strongly overexpressed in mouse and human hepatocellular carcinom
142 thyrointegrin alphavbeta3 receptors that are overexpressed in neuroblastoma and other neuroendocrine
148 rs and signaling pathways were significantly overexpressed in patients with CRS compared to controls,
149 unsaturated fatty acids (PUFAs), as robustly overexpressed in PCa tissues and associated with shorter
150 lls, we hypothesized that PIM kinases may be overexpressed in PMBL and involved in PMBL pathogenesis.
152 abolite profiling, we show here that DDX5 is overexpressed in SCLC cell lines and that its down-regul
159 the pCI-neo mammalian expression vector was overexpressed in the testis, to better understanding the
163 ally, we show in clinical data that SNHG7 is overexpressed in tumors of a subset of breast cancer pat
168 n was performed to identify genes that, when overexpressed, induce a reporter (FUS1-HIS3) that respon
171 t to overcome this defect, we generated mice overexpressing insulin receptors (IR) specifically in sk
172 +) (progenitor) cells in L2-IL1B mice (which overexpress interleukin 1 beta in esophagus and squamous
176 ells (HSCs), we show that OPN, besides being overexpressed, is substantially phosphorylated by family
178 markably, CD8(+) T cells in recurrent tumors overexpressed KLRB1 (CD161) and displayed an innate-like
179 ing a selection of 29 T. brucei mutants that overexpress known essential protein kinases, and identif
182 igiosin (PGS) and paclitaxel (PTX) drugs and overexpressed LHRH receptors on the breast cancer cells
183 ribution of tau protein species in human tau overexpressing line 66 mice, a transgenic mouse model ak
189 atory reaction underlying AD, where IL-13 is overexpressed locally and has a significant impact on sk
191 eutic roles of angiotensin-converting enzyme-overexpressing macrophages in preserving synapses and co
193 ed mucin 5AC (MUC5AC) is the most abundantly overexpressed member of the mucin family during early pa
194 erigonadal white AT (PGWAT) of chow-fed RBP4-overexpressing mice and in serum and PGWAT of high-fat d
195 l antibody attenuated kidney injury in suPAR-overexpressing mice and normalized bioenergetic changes
197 eveloped reproductive tract tumors, all PGRB-overexpressing mice developed ovarian neoplasms that wer
199 use atonal homolog 1 ratio in ilea from Msi1-overexpressing mice implicated Notch signaling in induci
201 mic analyses of the ovarian tumors from PGRB-overexpressing mice revealed enhanced AKT signaling and
204 teries from late pregnant wildtype and LOX-1 overexpressing mice were incubated overnight with or wit
210 9-3p or miR-9-5p inhibitors in K/VP.5 cells (overexpressed miR-9 and low TOP2alpha/170) led to increa
214 CLR01 in vivo in a humanized alpha-synuclein overexpressing mouse model; mice treated at 12 months of
215 disturbed Ca(2+) regulation in mut(PG1)JPH2 overexpressing myocytes caused calcium/calmodulin-depend
217 Importantly, mice transplanted with T-cells overexpressing NRARP alone developed leukemia with simil
218 nsive gene expression and AS changes in mice overexpressing nuclear and naturally localized CELF1 pro
222 Rescue of unc-13/Munc13 mutant phenotypes by overexpressed open UNC-64/syntaxin suggested a specific
223 blicly available database showed SNX27 to be overexpressed or frequently altered in the patients havi
224 Receptor tyrosine kinases (RTKs) are often overexpressed or mutated in cancers and drive tumor grow
226 vestigated the activity of CCT2 (CCTbeta) by overexpressing or depleting the subunit in breast epithe
230 lso much slower than that of WT viruses, and overexpressing P50 in this cell line enhanced mutant vir
234 ogenitor cells are genetically engineered to overexpress PD-L1 to produce immunosuppressive platelets
236 ll line with hypoxia-treated primary tubules overexpressing periostin, or treating such macrophages w
237 e reproductive tract, we generated mice that overexpress PGRA or PGRB in all PGR-positive tissues.
239 Following inoculation with AM fungi, BdRAM1-overexpressing plants showed higher arbuscule densities
241 of the double mutants could be eliminated by overexpressing PNP/PMP oxidase (PdxH) to decrease the PN
246 a-synuclein neurotoxicity by treating 4E-BP1-overexpressing primary neurons with alpha-synuclein pref
249 previous immunolocalization studies utilized overexpressed protein or commercially available antibodi
251 e baculovirus system, human GLS2 protein was overexpressed, purified and analyzed for posttranslation
252 The structures and conformations of soluble, overexpressed, purified S proteins have been studied in
254 n of Rspo2 in FGF pathway regulation in vivo Overexpressed Rspo2 inhibited elongation of Xenopus ecto
255 itro model of HSV-1 infection, we found that overexpressed RUNX1 could bind putative binding sites in
257 present in lower amounts in ATP sulfurylase overexpressing seeds compared to the wild-type seeds.
259 th sufficient avidity to recognize naturally overexpressed self-antigens in the context of self-HLA c
260 reatic, and lung cancer cells, respectively, overexpressed SHH at transcriptional and protein levels.
265 f systemic staphylococcal disease, a pstSCAB-overexpressing strain is significantly attenuated compar
266 is gap, here we developed a transgenic mouse overexpressing Sulf2 in hepatocytes under the control of
269 at pancreatic ductal adenocarcinomas (PDACs) overexpress the myelin regulatory factor (MYRF), an ER m
271 pluripotent stem cells (hPSCs), and then we overexpressed the candidate TFs in hPSC-ECs and measured
272 s of salt for sucrose production, we further overexpressed the sucrose synthesis genes in Synechococc
273 lus Calmette-Guerin ([BCG] BCG-disA-OE) that overexpresses the endogenous mycobacterial diadenylate c
274 ed pluripotent stem cells (hiPSCs) or hiPSCs overexpressing the antiapoptotic factor BCL2, transferre
275 mbinant adeno-associated virus (rAAV) vector overexpressing the chondrogenic sox9 transcription facto
276 ally viable therapeutic strategy for tumours overexpressing the epidermal growth factor receptor (EGF
279 early afterdepolarizations from any cause by overexpressing the inward rectifier K channel Kir2.1 in
281 m tuberosum (potato) macro-chloroplast lines overexpressing the tubulin-like GTPase protein gene FtsZ
283 in simulated winter conditions, while flies overexpressing tim show an increased incidence of reprod
285 o address this question, we generated 4E-BP1-overexpressing transgenic mice and confirmed marked redu
287 knockout (TrkC-KO) and nephron-specific TrkC-overexpressing (TrkC-OE) mice were generated to dissect
290 AHR pathway is selectively active in IDO/TDO-overexpressing tumors and is associated with resistance
296 y enhanced susceptibility when siR109944 was overexpressed, while FBL55 OE plants showed resistance t
297 nd decreased activity when ceRNA 3'UTRs were overexpressed, while the original study reported increas
299 on (vascular endothelial growth factor) were overexpressed with BAL neutrophilia compared with nonneu