ライフサイエンスコーパス: overhang

1 ally contain a 3' ssDNA G-rich protrusion (G-overhang).

2 e interaction between POT1 and the telomeric overhang.

3 es of the strand terminating with a 5'-ssDNA overhang.

4 p decreases with increasing length of the 5'-overhang.

5 le to the full stretch of 3' human telomeric overhang.

6 ion of the correct single-stranded telomeric overhang.

7 hange (DeltaR(ct)) is found by extending the overhang.

8 ction of free DNA ends to produce a 3'-ssDNA overhang.

9 nd nasally, frequently with Bruch's membrane overhang.

10 same duplex with a 3'-overhang or without an overhang.

11 meric or heteropolymeric sequences in the 5' overhang.

12 e leader-proximal repeat to the prespacer 3' overhang.

13 3'-overhang while Bax1 interacts with the 5'-overhang.

14 ociation of these proteins from the telomere overhang.

15 res terminate in a single-stranded 3' G-rich overhang.

16 correlating with the accumulation of long G-overhangs.

17 strands must first be resected to reveal 3'-overhangs.

18 -base-pair prespacer bearing 4-nucleotide 3' overhangs.

19 ni, including blunt ends and single-stranded overhangs.

20 RNA duplexes, and for duplexes with short 3' overhangs.

21 ends, including blunt, 5' overhangs, and 3' overhangs.

22 o the target DNAs with different lengths and overhangs.

23 Apollo is required for maintaining telomeric overhangs.

24 a similar substrate containing 5-nucleotide overhangs.

25 ctures compared with linear duplex having 3' overhangs.

26 -POT1 switch on telomeric single-stranded 3' overhangs.

27 ficant unwinding of substrates containing 3' overhangs.

28 3-fold lower compared with duplexes with 5' overhangs.

29 ferentiates pre-miRNA species with different overhangs.

30 similarities to hairpins and fixed 5' and 3' overhangs.

31 roduce double-stranded DNA molecules with 5'-overhangs.

32 ds unexpectedly form long 5' single-stranded overhangs.

33 erved due to transient binding of the sticky overhangs.

34 m all dsDNA ends: 5'-overhangs, blunt, or 3'-overhangs.

35 s (' ') to produce fragments with 2-base, 3'-overhangs.

36 wild-type Metnase effectively cleaves ssDNA overhangs.

37 the accessibility of pol mu to DNA ends with overhangs.

38 oson end binding resembles that of spacer 3'-overhangs.

39 n which DSB ends are converted into 3'-ssDNA overhangs.

40 es in the enzyme that can generate longer 3' overhangs.

41 st G to produce fragments with three-base 5'-overhangs.

42 n of DSBs to generate 3' single-stranded DNA overhangs.

43 and from DNA duplexes with single base pair overhangs.

44 define the steps in the processing of these overhangs.

45 d inhibiting unwinding of substrates with 3'-overhangs.

46 ike IDN2 and SGS3, FDM1 binds dsRNAs with 5' overhangs.

47 spI (C CGG), which produce fragments with 5'-overhangs.

48 first be processed into 3' single-strand DNA overhangs.

49 strands must first be resected to produce 3' overhangs.

50 A ends to expose single-stranded DNA (ssDNA) overhangs.

51 equence 5'-CCTCAGC-3', generating 3-base, 5'-overhangs.

52 rategy among NNS RNA viruses resulting in 3' overhangs.

53 RNA constructs, which retained 5' nucleotide overhangs.

54 mulate Artemis activity at hairpins or at 5' overhangs.

55 es out endonucleolytic cleavage of 5' and 3' overhangs.

56 activity mediated loading of Exo1 onto ssDNA overhangs.

57 han with single- or double-stranded DNA with overhangs.

58 commonly used 19mer with two deoxythymidine overhangs (19merTT) variant performed similarly to canon

59 reaction (PCR) fragment containing a single overhanging 3' A to a plasmid vector containing a 3' T.

60 In contrast, 3'-overhang/3'-overhang and 5'-overhang/5'-overhang templat

61 Finally, dephosphorylation of the 5'-overhang/3'-overhang template reduced the efficiency of

62 vitro assays to demonstrate that nucleotide overhangs 5', but not 3', proximal to the sgRNA do in fa

63 In contrast, 3'-overhang/3'-overhang and 5'-overhang/5'-overhang templates were processed by resecti

64 blunt/3'-overhang, blunt/5'-overhang, and 3'-overhang/5'-overhang were predominantly repaired with fi

65 breaks (DSBs) providing single-stranded DNA overhangs after their processing.

66 tranded telomeric DNA (ssTEL) and protects G overhangs against RPA binding.

67 In contrast, 3'-overhang/3'-overhang and 5'-overhang/5'-overhang templates were proc

68 h G1 stringently requiring a 5-nucleotide 3' overhang and G2 being able to insert many forms of presp

69 ing the detailed structure of the telomere G-overhang and its maintenance will contribute greatly to

70 vase that does not require a single-stranded overhang and that ATP hydrolysis is not directly coupled

71 fork substrates with 3' single-stranded DNA overhangs and also disrupts protein-DNA interactions whi

72 dition, purified CST complex binds to 5' DNA overhangs and directly blocks MRE11 degradation in vitro

73 in maintaining newly replicated telomeric 3' overhangs and facilitating the switch from replication p

74 by promoting unwinding of substrates with 5'-overhangs and inhibiting unwinding of substrates with 3'

75 t in stabilizing the hybridized state of the overhangs and magnifying the energy barrier to dissociat

76 (TERT)] in an effort to extend chromosomal G-overhangs and maintain telomere ends.

77 th complex structures including forked ssDNA overhangs and nucleoprotein conjugates.

78 including human telomeric GQ (with different overhangs and polarities) and GQ formed by thrombin-bind

79 ates, this protein preferentially cleaved 3'-overhangs and RNA in blunt-ended DNA/RNA duplexes.

80 the telomeric C strand, causing extended 3' overhangs and stochastic telomere truncations that could

81 By analyzing how the distribution of overhangs and their length and sequence modulate the ene

82 ISPR spacers through the formation of 3'-DNA overhangs and to the degradation of foreign DNA.

83 atible ends with blunt/3'-overhang, blunt/5'-overhang, and 3'-overhang/5'-overhang were predominantly

84 initial single-stranded DNA (ssDNA) at a 3'-overhang, and second in binding to SSB to facilitate ann

85 of varying the length of the single-stranded overhang, and studied A-form DNA-PNA duplexes to provide

86 rious types of DNA ends, including blunt, 5' overhangs, and 3' overhangs.

87 elicases, JFH-1 NS3 does not require long 3' overhangs, and it unwinds duplexes that are flanked by o

88 e nucleolytic resection of DNA with 5'-ssDNA overhangs, and that RecQ helicase can initiate resection

89 The overhang annealing is supposed to form circular plasmids

90 high-resolution insight into the telomeric G-overhang architecture under essentially physiological co

91 Telomere overhangs are essential for telomere end protection and

92 n and telomerase extension, but how telomere overhangs are generated is unknown.

93 the repeat unit and produce a duplex with 5'-overhangs, are extended using a thermostable archaeal DN

94 p formation does not require a single strand overhang, arguing that both terminal strands insert into

95 lity of gene 6 protein to remove 5'-terminal overhangs as well as to remove nucleotides from the 5'-t

96 nucleotides, containing a nontemplated 5'-G overhang, as in the natural genome context, as well as t

97 s with the binding stability of BLM to ssDNA overhang, as modulated by the nucleotide state, ionic co

98 assessment of the rate of formation of each overhang at each nucleotide position.

99 subunit TRF2, initiates formation of the 3' overhang at leading-, but not lagging-end telomeres.

100 -stranded siRNA with at least a 2-nucleotide overhang at one 3' terminus in a dose-dependent manner,

101 a complementary sequence (12-nt) to a G-rich overhang at the 3'-end.

102 odulation of targeting vectors to provide 3' overhangs at both ends increased the efficiency of homol

103 olled process, ensuring functional telomeric overhangs at chromosome ends.

104 mple, to remove RNA primers or to produce 3' overhangs at telomeres or double-strand breaks.

105 ned by the generation of 3 single-strand DNA overhangs at the break that are initiated by the action

106 We present an overhang-based DNA block shuffling method to create a cu

107 lease activity on single-stranded DNA and 5'-overhangs, because this 5'-exonuclease is not dependent

108 two adjacently positioned pockets: a 2 nt 3'-overhang-binding pocket within the PAZ domain (3' pocket

109 Moreover, non-compatible ends with blunt/3'-overhang, blunt/5'-overhang, and 3'-overhang/5'-overhang

110 combinational repair from all dsDNA ends: 5'-overhangs, blunt, or 3'-overhangs.

111 inds forked dsDNA and DNA duplexes with a 3'-overhang but is inactive on blunt-ended dsDNA and 5'-ove

112 bstrates possessing a 3' single-stranded DNA overhang but not of 5' overhangs or blunt-ended DNA frag

113 and resection required the presence of these overhangs but did not require Metnase's DNA cleavage act

114 haped DNA structures having >/=18-nucleotide overhangs but not to a similar substrate containing 5-nu

115 s containing 5' overhangs relative to the 3' overhangs but not to blunt-ended duplex.

116 terminal phosphate and a two-nucleotide, 3' overhang, but does not require ATP.

117 Without ATP, dmDcr-2 binds 3' overhanging, but not blunt, termini.

118 ty, particularly for ends with mismatched 3' overhangs, but the mechanism has remained obscure.

119 V alone can stimulate Artemis activity on 3' overhangs, but this DNA-PKcs-independent endonuclease ac

120 res the generation of a 3' single-strand DNA overhang by exonuclease activities in a process called D

121 resection of DNA with blunt-ends or 3'-ssDNA overhangs by DNA unwinding.

122 preferentially inhibits cNHEJ at breaks with overhangs by protecting them.

123 se of subsurface pressure or via creation of overhangs by sublimation, may be a major mass loss proce

124 core, oscillating between the two equivalent overhanging carbonyl groups, coupled to an intermolecula

125 PbOAc exchanging between the two equivalent overhanging carboxylate groups (N-core(up) left arrow ov

126 tion in a bis-strapped porphyrin ligand with overhanging carboxylate groups has been investigated in

127 A bis-strap porphyrin ligand (1), with an overhanging carboxylic acid group on each side of the ma

128 twice off the surface, then arrived under an overhanging cliff in the Abydos region.

129 Our results reveal how the overhangs collectively introduce a sharp free-energy min

130 ter duplexes with a single nucleotide 3'-DNA overhang complementary to the 3' nucleotide of the accep

131 omplex, larger DNA sequence that contains an overhang complementary to the CNA can also be encapsulat

132 Artemis at blunt DNA ends is slower than at overhangs, consistent with a requirement for a slow DNA

133 The overhangs corresponded to 2',3'-cyclic phosphate, 3'-pho

134 Crucially, 3 bp overhangs corresponding to start and stop codons are use

135 ALT cells possess excessively long telomeric overhangs derived from telomere elongation processes tha

136 state, ionic conditions, overhang length and overhang directionality.

137 cross-linked with an abasic site within a 3' overhang DNA.

138 he enhanced Exo1 nuclease activity by longer overhanging DNA is largely eliminated by replication pro

139 ingly, we demonstrate that A3H can deaminate overhanging DNA strands of RNA/DNA heteroduplexes, which

140 ex digestion was partially rescued by longer overhanging DNA.

141 und in DNA-damage sites, including 5' and 3' overhang DNAs and gapped DNAs with short single-strand s

142 At native telomeres in dna2 mutants, GT-overhangs do clearly elongate during late S phase but ar

143 RNAs with 5' overhangs does not compete with DNA for binding by FDM1,

144 rised of a T7 promoter and a single-stranded overhang domain (ss-dsDNA), can unlock dynamic DNA-based

145 ((SUB)P) is unusually narrow because of the overhanging +domain.

146 lated nucleotide additions during NHEJ of 5'-overhang DSBs or in clastogen resistance.

147 DSBs affects NHEJ, we made site-specific 5'-overhanging DSBs (5' DSBs) in yeast using an optimized z

148 Depletion of TEN1 does not effect overhang elongation in mid-S phase, but it delays overha

149 plexes having either a blunt end or a 3'-DNA overhang end.

150 in 5' TTAGGG 3', while a small portion of G-overhangs end in 5' TAGGGT 3'.

151 say, we found that most T. brucei telomere G-overhangs end in 5' TTAGGG 3', while a small portion of

152 By investigations of longer targets with overhangs exposed to the solution, we can demonstrate ap

153 protection involves the insertion of the 3' overhang facilitated by telomere repeat-binding factor 2

154 espect to stimulating Artemis activity at 3' overhangs, favoring the view that these NHEJ proteins ar

155 kness with this approach arises when melting overhanging features, which have no prior melted materia

156 Interestingly, MtDinG unwinds overhangs, flap structures, and forked duplexes but fail

157 rhaps by pushing the Ku inward to expose the overhang for NHEJ synapsis.

158 3' overhang formation is thus a multistep, shelterin-contro

159 cleavage sites and each of the six expected overhangs formed at nascent termini adjacent to the clea

160 NA binding region, DrII is able to remove 3' overhangs from RNA molecules closer to duplexes than do

161 Redbeta directly onto the single-stranded 3'-overhang generated by lambda Exo.

162 s for the interaction of HMCES with long DNA overhangs generated by Alt-EJ during CSR.

163 d that structural asymmetry (e.g. 5- or 2-nt overhang) has no impact on accumulation, but is a princi

164 d DNA2, which process DNA ends into 3' ssDNA overhangs; helicases such as BLM, which unwind DNA; and

165 ths and types (5' and 3') of single-stranded overhangs, if present, on each DNA fragment with an over

166 ultispecies coprolite assemblage from a rock overhang in a montane river valley in southern New Zeala

167 DNA (dsDNA) junction and reels in the ssDNA overhang in an ATP-dependent manner.

168 the phosphate pocket while retaining the 3' overhang in the 3' pocket.

169 s, does not lead to further shortening of GT-overhangs in dna2 mutants.

170 employs two restriction enzymes to generate overhangs in opposite orientations to which (single-stra

171 le-stranded DNA breaks to form long 3'-ssDNA overhangs in preparation for recombinational repair is c

172 telomere ends, generating transient long 3' overhangs in S/G2.

173 s blunt-ended or staggered-ended breaks with overhangs in the DNA.

174 emonstrated that the PCR enzyme fills the 5'-overhangs in the early cycles, and the product is then u

175 significantly affect the 5' TAGGGT 3'-ending overhangs, indicating that telomerase-mediated telomere

176 A 3' overhang is critical for the protection and maintenance

177 quence can be designed in a way that a small overhang is exposed to the electrode surface.

178 more than one Srs2 molecule on the 3' ssDNA overhang is required to initiate DNA unwinding.

179 The dsDNA product, with a 3'-ssDNA overhang, is an optimal substrate for RecQ, which unwind

180 ivity is most efficient on DNA containing 3' overhangs, is facilitated by an insertion loop and conse

181 eighbor models of DNA, due to the additional overhang it engenders at the junction.

182 her preference for duplex substrates with 5' overhangs, it could also catalyze significant unwinding

183 d by the nucleotide state, ionic conditions, overhang length and overhang directionality.

184 The overhang length dictates the frequency (but not duration

185 G-overhang length increases with time after CTC1 disruptio

186 double strands with different complementary overhang lengths can be studied using the same DNA origa

187 evels exhibit shorter telomeres, increased G overhang levels, and altered levels of non-homologous en

188 st that Drosophila telomeres possess a ssDNA overhang like the other eukaryotes, and that the termini

189 RT interaction with telomeres and leads to G-overhang loss.

190 The DNA contained a 15 nt overhang made entirely of thymidine residues adjacent to

191 In addition to 3' overhangs, many of these DNA ends unexpectedly form long

192 sults suggest that GQ formation of telomeric overhangs may contribute to suppression of DNA damage si

193 urfaces are created by designing an array of overhanging microdisks on a polymer film through two ste

194 f double-stranded (ds) DNA fragments with 3' overhangs mimicking double-strand breaks, and prevents r

195 This overhang must be protected against detrimental activitie

196 The method is based on replication of overhanging nanostructures from an aluminum tube templat

197 sed on the premise that 5'-and 3'-nucleotide overhangs negate Cas9/sgRNA catalytic activity in vivo.

198 -3', including a 3' terminal single-stranded overhang of 100-200 nucleotides that can fold into quadr

199 We find that the overhang of a pre-miRNA is the key structural element th

200 An "invader" strand binds to the "toehold" overhang of a target strand and replaces a target-bound

201 e terminal 5'-triphosphate of RNA and the 3'-overhang of DNA results in a stable complex between p58C

202 higher when dsDNA is GC-rich or when the 3'-overhang of forked DNA is <15 bases.

203 rt the prediction that in the full-length 3' overhang of human telomeres, G-quadruplexes with shortes

204 igonucleotide homologous to the 3'-telomeric overhang of telomeres, elicits potent DNA-damage respons

205 tructure derived from the single-stranded 3'-overhang of the telomeric DNA is an attractive strategy

206 ferredoxin-like fold, which recognizes a 3'-overhang of U6 snRNA, and a preceding peptide, which bin

207 tivity at DNA hairpins and at 5'- and 3'-DNA overhangs of duplex DNA, and this endonucleolytic activi

208 ease activity, cleaving the 3' single-strand overhangs of duplex RNA.

209 3'-PG and 3'-phosphate termini on 1-base 3' overhangs of NCS-C-induced DSBs were readily detected in

210 exonucleases DnaQ and ExoT can trim long 3' overhangs of prespacers and promote integration in the c

211 and NMR spectroscopies, we show here that G-overhangs of S. cerevisiae form distinct Hoogsteen pairi

212 either 5'- or 3'-single-stranded DNA (ssDNA) overhangs of undefined length.

213 moval of CTC1 results in elongation of the 3 overhang on the G-rich strand.

214 The effect of a target DNA overhang on the hybridization efficiency was shown to en

215 Nucleotide overhangs on the electrode side affected the signal more

216 s formed by hybridization of single-stranded overhangs on the linkers with the loops.

217 electrode side affected the signal more than overhangs on the solution side due to the greater insula

218 5'-overhang versus the same duplex with a 3'-overhang or without an overhang.

219 aired nicks, but, surprisingly, only when 5' overhangs or blunt ends can be generated.

220 ' single-stranded DNA overhang but not of 5' overhangs or blunt-ended DNA fragments.

221 in heterodimer, TauF4 is characterized by an overhanging peptide corresponding to the first of the fo

222 on of 3' DSBs, likely through recognition of overhang polarity by the Mre11 nuclease.

223 To better understand how overhang polarity of chromosomal DSBs affects NHEJ, we m

224 sults suggest distinct DSB handling based on overhang polarity that impacts NHEJ kinetics and fidelit

225 res can be controlled by the length of ssDNA overhangs positioned adjacent to the cholesterol.

226 Like CTC1 and STN1, TEN1 is needed for G-overhang processing.

227 Longer 3'-DNA overhangs progressively decreased the template-switching

228 The overhang provides a physical address for accessing speci

229 The 3' human telomeric overhang provides ample opportunities for the formation

230 d terminate in a single-stranded DNA (ssDNA) overhang recognized by POT1-TPP1 heterodimers to help re

231 After harvesting the complex, 3' overhang regions of the TRs were labeled with three dist

232 randed DNA and linear duplexes containing 5' overhangs relative to the 3' overhangs but not to blunt-

233 shelterin subunit TRF2 reduced telomeric 3'-overhang removal in time-course experiments, as well as

234 telomere damage signalling, nor in telomere overhang removal, which are critical for telomere fusion

235 break ends generates 3' single-stranded DNA overhangs required for homology-based DNA repair and act

236 Remarkably, Poltheta MMEJ of ssDNA overhangs requires polymerase-helicase attachment, but n

237 detachments and those with large, centrally overhanging schisis cavities were excluded from the anal

238 whereas 1.8% demonstrated a large, centrally overhanging schisis cavity requiring surgery (n = 1).

239 er specific to DNA polymerase containing the overhang sequence and the complementary blocker DNA, whi

240 ent target enzymes by simply redesigning the overhang sequence of detection probe, while keeping TaqM

241 can be estimated by the calculator from the overhang sequences or provided by the user from direct e

242 orked DNA, and the terminal 3'-OH of each 3' overhang serves as an attacking nucleophile during integ

243 ang elongation in mid-S phase, but it delays overhang shortening in late S/G2.

244 of DNA constructs with or without GQ in the overhang shows that GQ unfolding is achieved in 50-70% o

245 on by capturing two adjacent single-stranded overhangs simultaneously.

246 The G overhang spontaneously folds into various G-quadruplex (

247 strate that the presence and polarity of the overhang structure is a critical determinant of double-s

248 re synthesis is important for the telomere G-overhang structure.

249 ntially binds synthetic forked DNA or 3'-DNA overhang substrates resembling structures used during HR

250 Here, we determine the mechanism for 3' overhang synthesis in mouse cells by evaluating changes

251 lly, dephosphorylation of the 5'-overhang/3'-overhang template reduced the efficiency of DNA repair w

252 , 3'-overhang/3'-overhang and 5'-overhang/5'-overhang templates were processed by resection of 3-5 ba

253 ermini promote processive cleavage, while 3' overhanging termini are cleaved distributively.

254 in is required for binding blunt, but not 3' overhanging, termini.

255 end in a short, single-stranded DNA (ssDNA) overhang that is recognized and bound by two telomere pr

256 uently resected to form long single-stranded overhangs that can be repaired by mutagenic pathways.

257 d TbTR) and TbKu are required for telomere G-overhangs that end in 5' TTAGGG 3' but do not significan

258 by telomerase and resection to produce 3'-GT-overhangs that extend beyond the complementary 5'-CA-ric

259 ne can mediate efficient NHEJ synapsis of 3' overhangs that have at least 1 nt microhomology.

260 blique) and the presence of Bruch's membrane overhanging the border tissue.

261 Ray Exposure ages demonstrate that the cliff overhanging the Chauvet cave has collapsed several times

262 ch to the full length of the human telomeric overhang, the presence of higher-order quadruplex-quadru

263 Although FDM1 and IDN2 bind RNAs with 5' overhangs, their functions in the RdDM pathway remain to

264 sembly of short DNA blocks with dinucleotide overhangs through a simple ligation process.

265 estores the canonical end structure (2-nt 3' overhang) through mono-uridylation, thereby promoting mi

266 use cells by evaluating changes in telomeric overhangs throughout the cell cycle and at leading- and

267 amer and thereby bring the end of the G-rich overhang to close proximity to Ag NCs, resulting in a si

268 inding to SSB to facilitate annealing of the overhang to SSB-coated ssDNA at the replication fork.

269 multiple, short pairs of single-stranded DNA overhangs to components of the structure and triggering

270 These overhangs, together with the RADiation sensitive51 (RAD5

271 bound to Cas9 are devoid of the expected 5' overhangs transcribed by the virus.

272 or group II pre-miRNAs, which have a 1-nt 3' overhang, TUT7 restores the canonical end structure (2-n

273 f the nucleotide analogues into a DNA duplex overhang using recently evolved XNA polymerases is compa

274 these modified nucleotides into a DNA duplex overhang using the HNA polymerase T6G12_I521L are determ

275 ding an RNA duplex with a single-stranded 5'-overhang versus the same duplex with a 3'-overhang or wi

276 ggering hybridization or dissociation of the overhangs via changes in solution ionic conditions to dr

277 s2 preferentially selects prespacers with 3' overhangs via specific recognition of a PAM, but how the

278 A longer target DNA overhang was found to provide a better response.

279 When the overhang was on the electrode side the signal enhancemen

280 signal enhancement was greater than when the overhang was on the solution side due to the increased t

281 Bruch's membrane overhang was regionally present in the majority of patie

282 vidual duplex DNA molecules with symmetrical overhangs was carried out by pulling one strand of the d

283 A (pdDNA) constructs with different 5' ssDNA overhangs, we show that BLM localizes in the vicinity of

284 rhang, blunt/5'-overhang, and 3'-overhang/5'-overhang were predominantly repaired with fill-in and li

285 The results showed that compatible 5'-overhangs were accurately joined in all mutants, that KU

286 ays only edited DNA when 5' sgRNA nucleotide overhangs were removed, suggesting a novel processing me

287 test if the abasic site is within a short 5' overhang, when this activity is necessary and sufficient

288 ssed DNA end with a 40-nucleotide (nt) ssDNA overhang, where it localized to the ssDNA-dsDNA junction

289 is essential for Poltheta MMEJ of long ssDNA overhangs which model resected DSBs.

290 omeres terminate with a single-stranded 3' G overhang, which can be recognized as a DNA damage site b

291 nded DNA or duplex DNA with a four-base pair overhang, which is consistent with the known structure o

292 ent directions producing single-stranded DNA overhangs, which are potential intermediates for the syn

293 ed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly bound by replication protei

294 ed extremely slowly, indicating that short G-overhangs, which are typical for most of the cell cycle,

295 ween the two DNA strands and gripping the 3'-overhang while Bax1 interacts with the 5'-overhang.

296 led duplexes containing a 5' single-stranded overhang with an excess of unlabeled DNA to initiate the

297 etitive DNA sequence terminating in an ssDNA overhang with many associated proteins.

298 rtebrates, followed by a single-stranded DNA overhang with the same sequence.

299 stimulated Artemis to cut near the end of 3' overhangs without the involvement of other NHEJ proteins

300 e advantages enable the fabrication of large overhangs without the use of supports, reduction of the