ライフサイエンスコーパス: overrepresentation

1 tral DNA source sampling rather than plasmid overrepresentation.

2 t one of the enzymes of this pathway with an overrepresentation (60%) of viruses potentially infectin

3 hat displays the distribution of the motif's overrepresentation across loop geometries, enabling the

4 GlycoEnzOnto enables improved transcript overrepresentation analyses and glycosylation pathway id

5 Gene set enrichment analysis and overrepresentation analyses are commonly used methods to

6 ltered pathways/processes were identified by overrepresentation analyses of changed genes.

7 nistic insights into the underlying biology, overrepresentation analysis (ORA) is often conducted to

8 Pathway overrepresentation analysis and functional network analy

9 Overrepresentation analysis identified enrichment of dia

10 Gene ontology overrepresentation analysis in P7SCI gene-sets showed si

11 Overrepresentation analysis indicated that SP cells are

12 Overrepresentation analysis is used to identify biologic

13 Overrepresentation analysis of growth-correlated genes p

14 We also performed functional overrepresentation analysis of interacting proteins to u

15 ls enable ID mapping, pathway assignment and overrepresentation analysis of user-supplied data sets.

16 Pathway overrepresentation analysis pointed to a major involveme

17 Overrepresentation analysis suggested HOXA10 was involve

18 In benchmarks against existing overrepresentation analysis tools, only GeneTEA properly

19 Overrepresentation analysis was conducted for the three

20 bioinformatic analyses (Gene Ontology terms overrepresentation analysis, hierarchical clustering, an

21 In silico pathway overrepresentation analysis, protein-network mapping, ge

22 Based on overrepresentation analysis, several predominant biologi

23 idering signalling pathway topology, and the overrepresentation and magnitude of differentially-expre

24 e sensitive NestedMICA algorithm, as well as overrepresentation and pairwise motif matching capabilit

25 statistically overrepresented: however, male overrepresentation and related gender-based advantages a

26 It is important that actions to address both overrepresentation and underrepresentation are elements

27 onal genes further investigated for network, overrepresentation, and guilt-by-association analyses.

28 x1 gene dosage, 4.7% show Six1 amplification/overrepresentation, and tumors that exhibit an increase

29 while its inhibition decreases the degree of overrepresentation around a translocated reward.

30 These data implicate Six1 gene amplification/overrepresentation as a mechanism of Six1 mRNA overexpre

31 es and 5,510 internal controls confirmed the overrepresentation as statistically significant and repl

32 ry tumor material and cell line models, AGO2 overrepresentation associated (i) with higher disease bu

33 rentiating noise from true position-specific overrepresentation at single-nucleotide resolution.

34 .g., glycine in methionine biosynthesis) and overrepresentations (e.g., tryptophan in asparagine bios

35 hylogeny that are characterized by either an overrepresentation ("hot clades") or an underrepresentat

36 ed declarative memory system in favor of its overrepresentation in a cue-based sensory/emotional memo

37 genes were tested for biological and disease overrepresentation in annotation databases and for conne

38 binding sites for FOX TFs showed substantial overrepresentation in both advanced human and early muri

39 candidate oncogenes are identified based on overrepresentation in DEEPEST calls, and 1,078 previousl

40 l clustering in the genomes studied, and (v) overrepresentation in expressed sequences from reproduct

41 mor with poor overall prognosis and 1.5-fold overrepresentation in females.

42 Their marked overrepresentation in genomes, and largely unchanging de

43 d with lambda-type myeloma may relate to its overrepresentation in molecularly defined high-risk dise

44 f 118 479 individuals), we found significant overrepresentation in pediatric B-ALL (P = .004; odds ra

45 s cis-region, and (iii) exhibits a trend for overrepresentation in persons with reduced susceptibilit

46 The remarkable overrepresentation in the ATX1-regulated gene fraction o

47 ansion, associated with a lack of iTreg cell overrepresentation in the decidua.

48 simiae strain WCS417) also reveals WRKY TFs' overrepresentations in these pathways, suggesting a poss

49 ed categories, while P28SCI gene-sets showed overrepresentations in these same immune categories, alo

50 rs among predicted domain interactions, this overrepresentation is significantly lower than in the iP

51 Significant Six1 gene amplification and overrepresentation occurs in numerous breast cancer cell

52 stage-specific functional analysis revealed overrepresentation of "cell wall," "stress," and "develo

53 t an HLA-dependent mechanism is suggested by overrepresentation of "protective" class I alleles, such

54 of inferred haplotypes for IL12A revealed an overrepresentation of -798T/277A in subjects with high H

55 Overrepresentation of 3'-terminal sequences among cDNAs

56 One tumor had overrepresentation of 7q31 without any apparent anomaly

57 vealed overall underrepresentation of 8p and overrepresentation of 8q.

58 We have recently reported that overrepresentation of 8q24 (c-myc) is associated with cl

59 Overrepresentation of a 3-cell motif often known as the

60 onally active promoters and display striking overrepresentation of a consensus DNA sequence virtually

61 analyzed metal-specific TCR showed a common overrepresentation of a histidine in the complementarity

62 q data from cultured neurons, we find strong overrepresentation of a motif that matches our in vitro

63 AEI promoting the overrepresentation of a mutant allele might also play a

64 Overrepresentation of a single codon was typically plesi

65 0% vs. 77.8%, respectively; P=.037); and (4) overrepresentation of a specific PFGE genotype (85.7% vs

66 croarray data in ceh1 plants established the overrepresentation of a stress-responsive cis element an

67 We also found substantial overrepresentation of African-American patients among th

68 l eukaryotic genomes studied, we observed an overrepresentation of all repeats, especially homopurine

69 occal enzyme, staphylococcal LPXTGase has an overrepresentation of amino acids found in the peptidogl

70 ulation of cortical neurons, and we found an overrepresentation of amplitude edges.

71 Genetic analyses revealed an overrepresentation of antibiotic resistance genes.

72 amilies by DLBCL tumors was unbiased without overrepresentation of any particular V(H) gene or gene f

73 Notably, cortisol demonstrated an overrepresentation of associations with P < 0.05 compare

74 PRC1 complexes and requires a region with an overrepresentation of basic amino acids.

75 positional constraints, we investigated the overrepresentation of binding sites in the vicinity of o

76 We present a method for testing overrepresentation of biological pathways, indexed by ge

77 the significantly upregulated genes revealed overrepresentation of biological processes involved in I

78 s dampened in the Apc(1638N/+) mice, with an overrepresentation of c-myc target genes among those loc

79 tions to HPC area CA1 (LC-CA1) regulates the overrepresentation of CA1 place cells near rewarded loca

80 In comparison, an overrepresentation of cardinal orientations in the repre

81 The overrepresentation of cardinal tuned neurons was particu

82 This finding implies that overrepresentation of CD4(EM) cells is a unique feature

83 ve cells, apoptotic lymphocytes displayed an overrepresentation of CD45RO and HLA-DR expressing cells

84 The module of interest was characterized by overrepresentation of cell cycle-related genes (FDR = 3.

85 anscriptome analysis of nod mutants revealed overrepresentation of cell wall, hormone metabolism, and

86 However, there was a modest but significant overrepresentation of cells bearing Vbeta8 in the graft

87 onnectivity of cortical networks features an overrepresentation of certain wiring motifs compared to

88 initially were evolved to track the default overrepresentation of codons with preferred motifs.

89 MEK-ERK-regulated genes exhibited an overrepresentation of cognate sequences for the aryl hyd

90 Overrepresentation of conserved aromatic amino acids thr

91 Of particular note is the overrepresentation of conserved SCD-containing proteins

92 s, including statistically significant local overrepresentation of core promoter elements.

93 ter deficit of CpG dinucleotides, a stronger overrepresentation of CpG-containing n-mers surrounding

94 We identified a substantial overrepresentation of CPVT-associated variants in a larg

95 n cytogenetic subgroups of childhood ALL and overrepresentation of CRLF2-IL7R-JAK-STAT activating gen

96 d that exposure to adriamycin resulted in an overrepresentation of cytogenetic changes involving telo

97 Given the overrepresentation of depression and musculoskeletal dis

98 nocturnal hemoglobinuria, a seemingly random overrepresentation of different V beta families was obse

99 that showed highly statistically significant overrepresentation of dimers formed by structurally simi

100 infected individuals are associated with the overrepresentation of distinct B cell populations.

101 ased drug-selective pressures in the plasma, overrepresentation of DRMs in the central nervous system

102 y found in those on nonsuppressive cART, and overrepresentation of DRMs in the CNS can occur.

103 ng of HF cardiac fibroblasts highlighted the overrepresentation of dysregulated genes involved in ECM

104 ng of HF cardiac fibroblasts highlighted the overrepresentation of dysregulated genes involved in ECM

105 creased cue-evoked dopamine responses and an overrepresentation of effort-driven striatal encoding pa

106 evel, the proteome of AF(+) microglia showed overrepresentation of endolysosomal, autophagic, catabol

107 ut not those of an NKX2-5 YRD mutant, showed overrepresentation of ETS binding sites and were occupie

108 using Unigene cluster data mining, we found overrepresentation of expressed sequence tags correspond

109 Both models exhibited an overrepresentation of extra-large (XL) synapses, which e

110 The overrepresentation of females and blacks in the group of

111 The IL-6TS-high subset had an overrepresentation of frequent exacerbators, blood eosin

112 y a model of lateral inhibition based on the overrepresentation of frontal space observed in ICx.

113 of the differentially spliced genes revealed overrepresentation of functional categories related to t

114 ic and age-related diseases are caused by an overrepresentation of G4s.

115 le bioinformatics tools revealed significant overrepresentation of Gene Ontology clusters within hema

116 SNP, and an enrichment score reflecting the overrepresentation of gene-based association signals in

117 Pathway analysis revealed a significant overrepresentation of genes (18 of the 273 genes) involv

118 he WB discovery cohort, we found significant overrepresentation of genes associated with asthma contr

119 among the up-regulated genes, a significant overrepresentation of genes containing activation protei

120 ene biosynthesis, while having a significant overrepresentation of genes in the sphingolipid pathways

121 Gene ontology analysis showed overrepresentation of genes involved in apoptosis among

122 The overrepresentation of genes involved in calcium homeosta

123 y sites of loss in CR metastases, we find an overrepresentation of genes involved in cellular lipid m

124 differentially expressed genes pointed to an overrepresentation of genes involved in G protein-couple

125 n, and chromosome function, demonstrating an overrepresentation of genes involved in mitotic regulati

126 ce of any exogenous genotoxic agent, with an overrepresentation of genes linked to cancer.

127 of differentially expressed genes showed the overrepresentation of genes potentially involved in flor

128 We show an overrepresentation of genes related to neuronal function

129 An overrepresentation of genes with known functions and gen

130 in metabolism and receptor/signaling, and an overrepresentation of genes with unassigned function (32

131 ary and Ingenuity Pathways Analysis revealed overrepresentation of GO categories related to developme

132 ed a Bayesian approach (GO-Bayes) to measure overrepresentation of GO terms that incorporates the GO

133 te during the waiting period, but no general overrepresentation of goals by place fields, an observat

134 Regional differences included overrepresentation of graminoids in SA and AU and of ann

135 This was preceded by an overrepresentation of granulocytic cells in the bone mar

136 (IGF1R) genes of female centenarians showed overrepresentation of heterozygous mutations in the IGF1

137 es show different SFS; although both show an overrepresentation of high frequency derived sites, low

138 The results confirm previous findings of an overrepresentation of highly edited mRNA variants (which

139 ll pool, characterized by a disproportionate overrepresentation of HIV-1 proviruses integrated in ZNF

140 We report overrepresentation of HLA-DR2 and its serologic split HL

141 There was an overrepresentation of homeobox genes and 31% of the most

142 ted from Hardy-Weinberg equilibrium, with an overrepresentation of homozygotes.

143 h HPV-associated tumours revealed a striking overrepresentation of homozygous arginine-72 p53 compare

144 the FinnGen dataset independently confirmed overrepresentation of homozygous HFE variants in patient

145 Bioinformatic analysis showed an overrepresentation of hormone-nuclear receptors within t

146 , and multimapping, we were able to quantify overrepresentation of host RNA features among the sequen

147 one third of the whole cohort, including an overrepresentation of IGHV4-34 (15.5% overall).

148 w number of somatic mutations as well as the overrepresentation of IGHV5-51 among TG2-specific plasma

149 GLASS also found an overrepresentation of inactivating mutations in specific

150 these Treg cells was subtly altered, with an overrepresentation of IRF4-dependent transcripts.

151 und with relatively lower GC composition and overrepresentation of IS elements, similar to the minich

152 pronounced in the decidua, where there is an overrepresentation of iTreg cells.

153 mainly due to haplogroups U4 and U5a, and an overrepresentation of J (30%) similar to the pre-Roman r

154 Overrepresentation of Jlambda distal cluster C genes rea

155 fate based on enrichment analysis indicating overrepresentation of key odontogenic genes.

156 Many algorithms analyze enhancers for overrepresentation of known and novel motifs, with the g

157 etween cases (MCI and AD) and controls shows overrepresentation of large heterozygous deletions in ca

158 s from confocally-imaged larvae suggest that overrepresentation of liver mRNA in klf9(-/-) mutants is

159 ificant impact on community structure due to overrepresentation of low-GC genomic regions following l

160 gut-lung interaction cluster demonstrates an overrepresentation of lung commensals, including Prevote

161 eased m(6)A upon TRMT10A ablation contain an overrepresentation of m(1)G9-containing tRNAs codons rea

162 In 2016, to address the historical overrepresentation of male subjects in biomedical resear

163 It contributed to the unexpected overrepresentation of male-biased genes on the autosomes

164 Gene ontology analysis revealed the overrepresentation of many transcription factors involve

165 In addition, a massive overrepresentation of members of the luciferase-like mon

166 In contrast, we find the greatest overrepresentation of Mesolithic ancestry across the maj

167 to chromosome 11, suggesting a trend toward overrepresentation of methylation events on this chromos

168 not initiate randomly but with a significant overrepresentation of microtubules at diagonal angles wi

169 ects were mostly women (70.7%) and there was overrepresentation of minorities for unclear reasons.

170 Our model reveals an overrepresentation of mites associated with Rodentia (ro

171 led to eliminate the well-known X-chromosome overrepresentation of MR genes and candidate genes.

172 ion of MSI versus point mutations, including overrepresentation of MSI in euchromatic and intronic re

173 in tails), and fat-tailed sheep, we found an overrepresentation of MSY lineages y-HC and y-HB, respec

174 We further observed strong overrepresentation of multiple transcription factor bind

175 unt of paternal mutations, and only a modest overrepresentation of mutations at CpG sites.

176 rkers of inflammation are associated with an overrepresentation of neurovegetative symptoms, includin

177 The recently reported overrepresentation of Nigerian lineages in African North

178 We employed bioinformatic analysis to find overrepresentation of noise-minimizing operon organizati

179 Hence, the significant overrepresentation of nonsyntenic genes among SPE patter

180 Mox phenotype was characterized by abundant overrepresentation of Nrf2-mediated expression of redox-

181 In this study, overrepresentation of one T-cell receptor beta chain var

182 Previous studies suggest overrepresentation of particular polymorphisms within th

183 abnormal expression of germline V segments, overrepresentation of particular sequences that correspo

184 Moreover, infection is associated with overrepresentation of pathogen-specific phages, allowing

185 patients, who also exhibited dysbiosis with overrepresentation of pathogenic taxa and significantly

186 effects, with queen-destined larvae showing overrepresentation of patrigene-biased transcription rel

187 Given the possibility of an overrepresentation of perioral tics in this group of hig

188 strated successes, the limited diversity and overrepresentation of planar, sp(2)-rich structures in c

189 S is the most frequent presentation, with an overrepresentation of polymorphous ophthalmological symp

190 ansplant graft-versus-leukemia effect and an overrepresentation of poor prognostic factors in elderly

191 One of the NPPIs revealed significant overrepresentation of potentially pathogenic proteins.

192 Enrichment analyses revealed an overrepresentation of prior epigenetic associations with

193 lular compartments was determined and showed overrepresentation of protein kinases.

194 ated with the alarm pheromone response shows overrepresentation of protein metabolism, regulation of

195 the binding partners revealed a significant overrepresentation of proteins involved in nucleotide me

196 There was a significant overrepresentation of proteins involving chromosomal fun

197 Dermotype C included overrepresentation of Pseudomonas, Staphylococcus and St

198 This excess was driven by the overrepresentation of QQ homozygotes in the mothers of c

199 d functional categories revealed significant overrepresentation of R- and Y-enriched IDRs in metaboli

200 f genes clustered by VxInsight identified an overrepresentation of Rap1p and BUF (RPA) binding sites

201 The results further suggest that overrepresentation of rare variants in a specific ethnic

202 an neutral reference genes, but there was no overrepresentation of regulatory genes in the selected g

203 Canonical pathway analysis identified overrepresentation of relevant pathways involved in regu

204 nderrepresentation of Hispanic ethnicity and overrepresentation of reported smoking.

205 nificant contribution of genetic loading, an overrepresentation of risk genes for autism spectrum dis

206 The overrepresentation of risk variants among gene regulator

207 We determined that there was a significant overrepresentation of RNAs from introns and intergenic r

208 The overrepresentation of SCA transcripts in modules identif

209 We propose that the overrepresentation of secreted proteins as dominant targ

210 es in the phylogenetic tree with significant overrepresentation of sequences from a given source popu

211 sensitive to (1) local alignment errors, (2) overrepresentation of sequences in some branches and (3)

212 n colonic cells uncovered highly significant overrepresentation of sequences that bind TCF4, a transc

213 eable datasets and reduces sampling bias and overrepresentation of sequences.

214 We detected the overrepresentation of several genera such as YS2/Cyanoba

215 approach to analyze variants and identified overrepresentation of several pathways, including cytosk

216 tatistically significant (P = 6.41 x 10(-4)) overrepresentation of shared associations in development

217 The significant overrepresentation of similar groups of DEGs in the tran

218 tirely semantic, and the cerebellum contains overrepresentation of social semantic information compar

219 th environmental and clinical ESBLEC and the overrepresentation of some clonal complexes.

220 ilico promoter analysis revealed significant overrepresentation of SP1/SP3-binding sites and/or GC-ri

221 We hypothesize that significant overrepresentation of specific gene ontology classes (e.

222 The observed overrepresentation of specific mutations within a subgro

223 The observed overrepresentation of specific mutations within a subgro

224 Finally, overrepresentation of specific promoter motifs in root-

225 eceptor (TCR) and/or CD28-coreceptor without overrepresentation of specific TCR clonotypes.

226 the resensitizing loci revealed significant overrepresentation of spindle checkpoint pathway genes.

227 nge of costless metabolites, resulting in an overrepresentation of stable ecological network motifs.

228 Genetic regulatory networks include an overrepresentation of subgraphs commonly known as networ

229 ated in doxycycline-treated dTg-211 cortices overrepresentation of synaptic activity, Ca(2+) transmem

230 Sequence analysis of hTERT and hTERC showed overrepresentation of synonymous and intronic mutations

231 gs with CATH functional families through the overrepresentation of targets of those drugs in CATH fun

232 ally infer such associations, by looking for overrepresentation of TCRs in individuals with a common

233 ic characteristics, with the exception of an overrepresentation of tertiary-educated women (88.7% com

234 We obtained a statistically significant overrepresentation of TF sites distributed with the main

235 f the chromosome 7 centromere and additional overrepresentation of the 7q-arm.

236 tor, is genetically associated with AD, with overrepresentation of the allele containing five copies

237 ly younger age at presentation, and a marked overrepresentation of the apolipoprotein E epsilon 4/eps

238 set enrichment analysis also demonstrated an overrepresentation of the apoptosis pathway in active di

239 of up-regulated genes revealed a significant overrepresentation of the AtMYB2-binding motif (GT motif

240 ored tumors with high epithelial content and overrepresentation of the C4/differentiated molecular si

241 a6 Furthermore, defective HDA6 results in an overrepresentation of the canonical poly(A) signal (AAUA

242 We also find overrepresentation of the exon 9 missense allele Phe607

243 , yet in the SLE patients, there was a clear overrepresentation of the FcgammaRIIa-R131;FcgammaRIIIa-

244 A strong overrepresentation of the gene segment TRAV9-2 was uniqu

245 preference syndrome that is characterized by overrepresentation of the hearing ear in the auditory sy

246 other cytokine receptor, gp130, resulting in overrepresentation of the heterodimeric receptor for OSM

247 in-2 gene transcripts in arterial tissue and overrepresentation of the HLA-DRB1*0404 allele, indicati

248 tation and used focused IGHV repertoire with overrepresentation of the IGHV3-48, IGHV4-59, IGHV5-10-1

249 lonal IGHV gene sequences were detected with overrepresentation of the IGHV4 family and IGHV4-34 gene

250 ke gut bacterial community, characterized by overrepresentation of the key genera Exiguobacterium, Pl

251 ted by wt HSV-1, and there was a significant overrepresentation of the long terminus and underreprese

252 Overrepresentation of the paternal genome in sporadic hy

253 Overexpression models confirmed that the overrepresentation of the pathogenic PEX6 c.2578T varian

254 pographies in the tectum was found, i.e., no overrepresentation of the retina was seen in the tectum

255 Overrepresentation of the TCRBV3 gene mRNA was demonstra

256 n plans to emerge in the DMS, as well as the overrepresentation of the to-be-inhibited behavior.

257 usage of Jkappa5 segments, and a significant overrepresentation of the Vkappa1 and Vkappa4 families,

258 were assigned probabilities according to the overrepresentation of their separation distance.

259 We conclude that overrepresentation of these chromosomal regions is a cri

260 Functional analysis revealed overrepresentation of these protein in biological proces

261 An algorithm that detects overrepresentation of these signature genes in a gene gr

262 More interestingly, overrepresentation of these TFBS was observed in hyper-/

263 Overrepresentation of these two Vbetas did not occur in

264 ng B cell development may be responsible for overrepresentation of these VH genes.

265 Notably, the overrepresentation of this biological term also correlat

266 There is a significant (> six-fold) overrepresentation of TPMT deficiency or heterozygosity

267 s between summer and winter births indicated overrepresentation of transcription factors HIF1A, VDR,

268 analysis of affected scalp tissue highlights overrepresentation of transcripts encoding components of

269 tion of degranulation, including significant overrepresentation of transcripts encoding tyrosine phos

270 ctivated population and included significant overrepresentation of transcripts for mast cell protease

271 Bioinformatic classification uncovered overrepresentation of transmembrane transporters, protei

272 typically plesiomorphic, and transitions to overrepresentation of two codons occurred commonly acros

273 A significant overrepresentation of two genetic hits was detected for

274 nalysis of the unique gene set identified an overrepresentation of type I interferon (IFN)-associated

275 In silico promoter analysis indicated an overrepresentation of type-B Arabidopsis response regula

276 KEA3) is a webserver application that infers overrepresentation of upstream kinases whose putative su

277 l power for detection of SNPs to account for overrepresentation of variants with larger effect sizes

278 imate that there is an approximately 10-fold overrepresentation of visual information.

279 ce ratio is expected to worsen by 2050, with overrepresentation of white participants vs underreprese

280 udies should further investigate whether the overrepresentation of women is caused by differences in

281 atlantic trade in enslaved Africans, and the overrepresentation of Yoruba peoples in the existing lim

282 Explainable differences (e.g., overrepresentation of younger people) were found for age

283 Overrepresentations of findings with P < 0.05 from these

284 alysis in P7SCI gene-sets showed significant overrepresentations only in immune-associated categories

285 s) were identified using DEseq2, followed by overrepresentation pathway (Gene Ontology [GO] and Kyoto

286 d to find motifs by simultaneously using the overrepresentation property and the evolutionary conserv

287 ing motifs by simultaneously using the motif overrepresentation property and the motif evolutionary c

288 gene profiles demonstrated selected pathway overrepresentation related to particular bacterial compl

289 oximately 10% of MCC patients, a significant overrepresentation relative to the general population.

290 ines PC3 and DU145 have and do not have 8q24 overrepresentation, respectively.

291 ated GO terms to strengthen the detection of overrepresentation signals.

292 The overrepresentation test is also available as a web servi

293 and Wnt signaling pathways were positive in overrepresentation test, and, in addition, many genes we

294 of these gene transcripts indicates a slight overrepresentation toward locations on the distal long a

295 Overrepresentation, underrepresentation, or representati

296 In 6 of the 10 individuals with Vbeta14 overrepresentation, Vbeta14 represented >20% of the enti

297 s meeting at least one criterion for Vbeta14 overrepresentation was shown to increase in tandem with

298 The extent of this overrepresentation was stronger in mice than in humans,

299 is, and leprosy demonstrated review/protocol overrepresentation when matched with corresponding DALYs

300 sequence is analyzed at the clone level for overrepresentation within a whole-genome shotgun sequenc