ライフサイエンスコーパス: overt

1 ed, but vascular imaging did not demonstrate overt abnormalities.

2 ed to the collecting duct does not result in overt activation of the Ire1alpha-Xbp1 pathway or cause

3 gastrointestinal bleeding (occult/anemia or overt/active, OGIB) of 46% (246/536) and definite/suspec

4 ow an autism-relevant phenotype that becomes overt after an acute stressor, emphasising the importanc

5 e processes, we obtained data from subjects' overt allocation of gaze.

6 urprisingly, this effect was observed before overt amyloid deposition.

7 Separating defences into overt and covert categories in this way and whether they

8 in and has been shown to be possible in both overt and covert conditions.

9 Overt and covert racist laws and policies, personal impl

10 ield (FEF) is a critical cortical region for overt and covert spatial attention.

11 ) is a critical region for the deployment of overt and covert spatial attention.

12 maps in sensorimotor regions known to guide overt and covert spatial selection are influenced by per

13 the ability of humans and monkeys to perform overt and covert target selection in the presence of spa

14 Further studies are needed in athletes with overt and pathological hypertrophy to establish whether

15 Overt and subclinical hyperthyroidism affected 0.26% and

16 ng those not on treatment, the prevalence of overt and subclinical hypothyroidism was 0.82% and 6.06%

17 age groups, which has been attributed to the overt and uncontrolled activation of host immune respons

18 tors or investigate the relationship between overt- and covert-attention-defined centers.

19 In vivo experiments also demonstrate overt anesthetic activity in both tadpoles and rats with

20 The site of overt attention (fixation point) defines a spatial refer

21 ms a visual-to-motor transformation vital to overt attention, but existing SC models cannot predict s

22 are compatible with the view that covert and overt attentional orienting are guided by feedback proje

23 pulations in normal numbers and exhibited no overt autoimmune manifestations.

24 nd, some develop autoimmune-like symptoms or overt autoimmunity characterized by autoantibody product

25 nrichment was clearly depicted in those with overt BBB disruption, while paravenous and parasinus men

26 ory modalities, individual history biases in overt behavior were consistently explained by a history-

27 In the absence of external stimuli or overt behavior, the activity of the left and right corti

28 c reference frame prior to implementation as overt behavior.

29 es and environment and, in turn, causing the overt behaviours from which it is often inferred.

30 Each of the 10 patients who developed new overt bioprosthesis dysfunction during follow-up had evi

31 jor bleeding (fatal, critical, or clinically overt bleeding or bleeding at the surgical site leading

32 human donors, selected for their absence of overt cardiac disease.

33 ung CaMKIIdelta TG mice (6-8 weeks) where no overt cardiac dysfunction was present.

34 entions are needed to prevent progression to overt cardiometabolic diseases.

35 Atherosclerosis), a cohort initially free of overt cardiovascular disease (CVD).

36 ts with nonelevated clinic BP, no history of overt cardiovascular disease, and no use of antihyperten

37 categories often emerge incidentally without overt categorization or explicit feedback.

38 e been investigated almost exclusively using overt categorization tasks with explicit feedback about

39 a category boundary, predicted participants' overt category judgments, emerged shortly after stimulus

40 The presence of these RNAs in the absence of overt central nervous system (CNS) disease has led to th

41 is inhibitory action was not associated with overt circadian rhythmicity in GHT output, indicating mo

42 r disease on ultrasound or gastroscopy); (2) overt cirrhosis (OvC) (TE >=13 kPa with signs of cirrhos

43 ouse palate, and knockout animals develop an overt cleft palate.

44 ding protein do not necessarily present with overt clinical phenotypes.

45 dynamic relationships that exist between the overt clinical signs, the microbial biofilm, and the hos

46 ations which do not necessarily present with overt clinical symptoms early in life and are more likel

47 pairment in older adults before the onset of overt clinical symptoms using metabolomics.

48 ivation at early stages of disease, prior to overt clinical symptoms with high sensitivity and specif

49 es the intestinal tract without inducing any overt clinical symptoms.

50 D pathology even prior to the development of overt clinical symptoms.

51 Patients with overt CNS disease (CNS3; >= 5 WBCs/muL with blasts) rece

52 S prophylaxis for children with B-ALL and no overt CNS involvement remains IT MTX.

53 ed channels are functional and contribute to overt co-operative gating behaviour of Ca(V) 1.2 channel

54 Rag(-/-) mice developed overt colitis with intestinal fibrostenosis.

55 evaluated during an 8-month surveillance: no overt constitutional or neurologic dysfunction was noted

56 Patients free of overt coronary (summed stress score <3 and without a his

57 ior heart surgery, myocardial infarction, or overt coronary artery disease were included.

58 n and cardiovascular events in those without overt coronary artery disease.

59 s saccading to a relevant stimulus can be an overt correlate of the allocation of spatial attention,

60 precisely timed gaze stabilization can be an overt correlate of the allocation of temporal attention.

61 ies of PitERtgKO adult mice displayed a more overt cystic and hemorrhagic phenotype when compared wit

62 rhabdovirus (Sf-RV) that does not cause any overt cytopathic effects.

63 ions included hematoxylin-eosin staining for overt damage, immunofluorescence for necroptosis, and Si

64 Signals drawing attention to overt defences are difficult to fake whereas signals adv

65 artments into the host cytosol often without overt destruction of the infected cell.

66 steep rise up to 72 hours before clinically overt deterioration has the potential for physicians to

67 lence of undiagnosed hyperglycaemia and even overt diabetes in young women is increasing.

68 Loss of beta cell area, even without overt diabetes or pancreatitis is consistently observed.

69 mpaired beta cell proliferation, and induced overt diabetes.

70 transition of impaired glucose tolerance to overt diabetes; endoplasmic reticulum (ER) stress expedi

71 e <30 mL/min per 1.73m(2), or development of overt diabetic nephropathy), eye events (a composite of

72 sive somatosensory behavioural tasks, but no overt differences in many other sensorimotor behaviours.

73 of tumor histopathology revealed features of overt differentiation with papillary characteristics.

74 f diabetes and its complications long before overt disease develops.

75 tomatically infected with viruses that cause overt disease in other species.

76 (AWM), for which the risk of progression to overt disease is not well defined.

77 rates that aberrant gene expression precedes overt disease onset in HD, identifies the Elk-1 transcri

78 modeling pathways up to two decades prior to overt disease onset.

79 nd at high risk of progression to clinically overt disease, would allow treatment to be targeted at t

80 ng after acute control and in the absence of overt disease.

81 biomarkers of T2D even over a decade before overt disease.

82 micro-colony formation and invasion, without overt disease.

83 e of asymptomatic nasopharyngeal carriage to overt disease.

84 ng and possibly preventing transition to the overt disorder.

85 rom the intention-to-treat population (3 had overt distant metastases at the time of randomization; 2

86 ng others, can appear years earlier than the overt dopaminergic neuron degeneration that drives motor

87 ricular (LV) dysfunction before the onset of overt Duchenne muscular dystrophy-associated cardiomyopa

88 In basal conditions, no overt dystonic movements or postures or change in locomo

89 Global deletion of SAM has no overt effect on mice but impairs adult muscle regenerati

90 There was no overt effect on neuronal viability, but defects of mitoc

91 e DNA, a DNMT3A-preferred target, but has no overt effect on the ability to methylate minor satellite

92 e and -infected isogenic strains revealed no overt effects of the virus.

93 a that, even in absence of hyperglycaemia or overt endotoxaemia, synergistically induce TLR4-mediated

94 Despite no overt epigenetic or DNA repair abnormalities, CHD6 loss

95 fic CD8(+) T cell transcription preceded the overt establishment of T cell exhaustion, making this si

96 ert spatial attention and the probability of overt exploratory movements are tethered to theta-band a

97 Traditional lineups rely on overt eyewitness responses that confound two covert fact

98 tify intact proviruses, defined by a lack of overt fatal defects such as large deletions and APOBEC3G

99 icient for both macroH2A1 variants harbor no overt female defects.

100 HCC in obesity in the absence of NASH and/or overt fibrosis or cirrhosis have remained unexplored.

101 nstrate that prenatal PBO exposure can cause overt forebrain and face malformations or neurodevelopme

102 ion contributes to H. pylori persistence and overt gastric disease.

103 In patients with overt gastrointestinal bleeding, and negative findings o

104 aft loss could rarely be detected before the overt graft loss observed via uncontrolled blood glucose

105 control participants), and participants with overt HCM (P < .001 vs control participants), respective

106 or LV hypertrophy], and 42 participants with overt HCM [positive for sarcomere mutation and negative

107 ide), cTSD was predictive of preclinical and overt HCM disease status (P < .01).

108 r control participants, preclinical HCM, and overt HCM was 14% +/- 4, 17% +/- 4, and 22% +/- 7, respe

109 nce of MHE and related to the development of overt HE and survival in patients with liver cirrhosis.

110 as the role of PPI use in the development of overt HE and survival.

111 that are designed to define early HE, using overt HE as a gold standard and expanding prediction too

112 ated with MHE and by time-related models for overt HE development and survival.

113 endently associated with MHE and the risk of overt HE in patients with cirrhosis; in malnourished pat

114 urately and efficiently classify the risk of overt HE in the population with cirrhosis, novel strateg

115 Overt HE is clinically obvious disorientation, even coma

116 Thirty-one (48%) patients developed overt HE over 16.1 +/- 13 months; myosteatosis was detec

117 During follow-up, the development of overt HE was higher (64% versus 25%, P < 0.001) and over

118 pendently associated with the development of overt HE were PPIs, history of overt HE, low albumin, MH

119 he presence of MHE were sarcopenia, previous overt HE, and myosteatosis.

120 h the presence of MHE were PPI use, previous overt HE, low albumin, low sodium, and age.

121 evelopment of overt HE were PPIs, history of overt HE, low albumin, MHE, and age, while variables ind

122 ed that validate these methods in predicting overt HE, many are impractical in clinical practice, and

123 ted with mortality were PPIs, development of overt HE, Model for End-Stage Liver Disease score, low s

124 nimal HE (MHE) and their role in the risk of overt HE.

125 h the prevalence of MHE and the incidence of overt HE.

126 l competing strategies for the prediction of overt HE.

127 pendently associated with the development of overt HE.

128 Overt hematologic malignancies were diagnosed in 16 pati

129 human aging, confers a risk of evolution to overt hematologic malignancy, and increases all-cause mo

130 at MSC therapy improves survival not through overt hematopoietic rescue but by positive impact on oth

131 and related to some complications including overt hepatic encephalopathy (HE).

132 ger times both TAC and TG mice progressed to overt HF (at 45 days and 11-13 weeks, respectively), dur

133 These changes are in the absence of overt histopathological changes or muscle loss.

134 the earliest forms of tau pathology, before overt histopathological lesions (i.e., neurofibrillary t

135 Clinically overt hormone excess was unlikely to develop (<0.1%) in

136 Overt hyperglycemia (>250 mg/dL) manifested 6 weeks afte

137 stology and 117 patients with subclinical or overt hyperthyroidism.

138 al dysfunction not only in participants with overt hypertrophic cardiomyopathy, but also in carriers

139 All patients with overt hypothyroidism should be treated, but those with s

140 ine levels may be below the reference range (overt hypothyroidism) or within the reference range (sub

141 the possibility of preventing progression to overt hypothyroidism.

142 ater risk of progression from subclinical to overt hypothyroidism.

143 ay suggest an explanation for the lack of an overt immune response to this organism.

144 Coexpression of MafB with MafA had no overt impact on mouse beta-cells, suggesting that the hu

145 No overt impairment of verbal and visual memory was identif

146 No overt impairments in the ability to engage in sniffing w

147 ansmission cycle to start, an outbreak of an overt infection must first occur within the host.

148 nicate fluid cultures subsequently developed overt infection.

149 ting memory CD4(+) T cells in the absence of overt infection.

150 nic and synaptic gene pathways with disease, overt inflammation was not evident by microglial morphol

151 ncluding those that emerge in the absence of overt inflammation.

152 Unexpectedly, this occurs in the absence of overt inflammation.

153 on and remyelination, even in the absence of overt inflammation.

154 ntly of the cognitive processes that support overt insights into the nature of our dietary decisions.

155 e studied a cohort of 19 children who had an overt ischemic stroke before 4 years of age.

156 While gender may no longer be an overt issue in perceived performance of senior staff in

157 Although no overt kidney phenotype was observed in Sirt5(-/-) mice,

158 H&E staining revealed overt lesions in the pancreas, liver, kidney, esophagus,

159 metastases to rapidly growing and clinically overt lesions.

160 Significant impairment of liver function or overt liver failure as the cause of death in COVID-19 ra

161 and a failure to adapt, with progression to overt liver injury.

162 t peripheral and brain tissue, suggesting no overt loss of function.

163 There was no overt loss of glial or neuronal adhesion, even at high-g

164 -positive, early-stage breast cancer without overt lymph node metastases.

165 e outgrowth of disseminated tumor cells into overt macro-metastases.

166 Notably, the absence of and reduction in overt maternal inflammation during stress indicates that

167 conditions, but do not consistently exhibit overt metabolic phenotypes when given ad libitum food ac

168 lls leaving the primary tumour and growth of overt metastases(2,3).

169 often begins long before the development of overt metastases, revealing the inefficient nature of th

170 idue diseases and prevention of life-taking, overt metastases.

171 nder dormancy, and the eventual outgrowth of overt metastases.

172 o secondary organs, 4T1 tumor models develop overt metastasis while EMT6-tumor bearing mice clear DTC

173 rs before resuming proliferation and causing overt metastasis, which causes bone destruction via acti

174 ream and promotes their ability to establish overt metastasis.

175 e distant metastatic site(s) before becoming overt metastatic diseases.

176 hese effects were observed in the absence of overt microglial depletion, suggesting that targeting CS

177 veness and tolerance to missing-self without overt missing-self reactivity.

178 athy at ~13 months of age, presumably due to overt mitochondrial dysfunction.

179 malignant clones prior to the development of overt MM.

180 m the aberrant plasma cell clone to MGUS and overt MM.

181 dii infection likely outweigh the recognised overt morbidity caused by toxoplasmosis, substantially r

182 ish lacking cdnf grows normally and shows no overt morphologic phenotype throughout the life span.

183 ripheral hyperactivity that occurred without overt morphological damage.

184 No overt morphological differences were recorded for vessel

185 sub-laminar resolution has found that, while overt motor actions led to activity in both superficial

186 ing behaviors across species, including both overt motor orienting [1, 2] and orienting of attention

187 Sensorimotor control during overt movements is characterized in terms of three build

188 ich includes kwashiorkor, presents with more overt multi-organ dysfunction than non-edematous SAM (NE

189 ch poor outcomes requires looking beyond the overt muscle loss and at this entity as a systemic disea

190 r usually from the second decade of life and overt myoclonic or generalised tonic-clonic seizures.

191 Finally, overt nephropathy is characterized by proteins involved

192 The overall conversion rate from iRBD to an overt neurodegenerative syndrome was 6.3% per year, with

193 he high phenoconversion rate from iRBD to an overt neurodegenerative syndrome.

194 n compared to wild-type controls but show no overt neurologic phenotype.

195 Cre or Dlx5/6-Cre did not induce seizures or overt neurological dysfunction.

196 Neuritic retraction in the absence of overt neuronal death is a shared feature of normal aging

197 distal axonal degeneration in the absence of overt neuronal death.

198 the hippocampus of AS mice in the absence of overt neuronal loss or mossy fiber sprouting.

199 without triggering leukocyte recruitment or overt neuropathology.

200 LE patients both with and without clinically overt neuropsychiatric manifestations, we found changes

201 patients with chronic kidney disease without overt obstructive coronary artery disease, but the mecha

202 ividuals before neurological disease becomes overt or serious.IMPORTANCE The detection of highly comp

203 selection of visual information either with (overt) or without (covert) foveating eye movements is cr

204 r hematopoietic stem cell function or induce overt pathological consequences.

205 Emd null mice show no overt pathology and have normal skeletal muscle but with

206 Our secondary outcome was the diagnosis of overt PH in patients initially diagnosed with borderline

207 Ryr1TM/Indel mice exhibit an overt phenotype beginning at 14 days of age that consist

208 ozygotes until birth, and the absence of any overt phenotype in heterozygotes provides important in v

209 EC-specific cox10 gene deletion produces no overt phenotype.

210 use its abrogation has been reported without overt phenotypes in mice and Drosophila This was address

211 in the mouse and observed that although the overt phenotypes of both cluster deletions were unremark

212 More patients with overt PMF were in higher International Prognostic Scorin

213 RSF2, IDH1/2, EZH2) were more represented in overt PMF.

214 d ERK activity in the trophectoderm prior to overt polar versus mural differentiation.

215 nt markers of associative threat learning to overt post-traumatic stress disorder (PTSD) symptoms in

216 Biochemically overt primary aldosteronism was diagnosed when urinary a

217 usted prevalence estimates for biochemically overt primary aldosteronism were 11.3% (CI, 5.9% to 16.8

218 predictive value for detecting biochemically overt primary aldosteronism.

219 vides an immediate and simple solution to an overt problem.

220 it the damaging inflammation associated with overt production of proinflammatory IL-1beta.

221 ophages with a nonredundant role in limiting overt proregenerative functions of AAM s, a role distinc

222 pertension (AASK) Cohort Study who exhibited overt proteinuria have been reported to show high nonalb

223 (oxLDL) particles, a process that induces an overt prothrombotic phenotype.

224 ms of schizophrenia and their evolution into overt psychosis may stem from an aberrant functional reo

225 encing subthreshold PSs and individuals with overt psychotic disorders support the notion of a psycho

226 We obtained no evidence for overt radial or tangential neuronal migrations.

227 Driven by the overt recognition of such a potential obstacle, a panel

228 n, and parturition stressors did not lead to overt/recrudescent clinical disease, but intermittent vi

229 novel strategy to prevent dissemination and overt relapse in multiple myeloma.

230 These animals have no overt renal phenotype.

231 stimulus uncertainty, behavioural relevance, overt reports, and motor responses.

232 plained in terms of stimulus uncertainty and overt reports.

233 In both manual (covert) and oculomotor (overt) response modalities, and in both humans and monke

234 ns are associated with those most at risk of overt rheumatological manifestations.

235 We also found that overt rhythmic movements improved the quality of tempora

236 iming the clock, but how this contributes to overt rhythms is unclear.

237 amic circadian oscillator network that times overt rhythms of physiology and behavior.

238 to drive rhythmic transcription required for overt rhythms.

239 lectively, our data suggest that there is no overt risk from exposure to Sf-RV.

240 rity of individual zebrafish lncRNAs have no overt roles in embryogenesis, viability and fertility.

241 population activity structure decoupled from overt rule-learning, and the other a directional change

242 uld learn how much the participant sampled ("overt sampling").

243 A cohort of 40 children with clinically overt sepsis and 30 children immediately postcardiopulmo

244 cts in brain-injured mice without displaying overt side effects.

245 h-LCN2 decreases food intake by 21%, without overt side effects.

246 or death, we randomly assigned patients with overt signs of acute upper gastrointestinal bleeding and

247 GFR declines with healthy aging without any overt signs of compensation (such as elevated single-nep

248 he maturation stages was unaffected, with no overt signs of developmental blocks.

249 nt, maintained their identity, and showed no overt signs of shifting to an epidermal fate.

250 ERX-11 is orally bioavailable, with no overt signs of toxicity and potent activity in both muri

251 There was no lethality or overt signs of toxicity at either dose level.

252 nsequently contributed to the development of overt skin disease.

253 Comparatively, neonatal mice did not develop overt skin inflammation, but exhibited systemic release

254 Vaccination with BCG-MNA caused no overt skin irritation, in marked contrast to intradermal

255 notype with overall flaky appearance, but no overt skin phenotype in adulthood, thereby reflecting a

256 from elevated GH release to the formation of overt somatotropinomas in Aip+/- mice; the acromegalic p

257 Covert and overt spatial selection behaviors are guided by both vis

258 al form recognition contribute to covert and overt spatial selection behaviors remains unclear.

259 al form recognition contribute to covert and overt spatial selection.

260 to which this verbal content is processed as overt speech in the brain.

261 cephalographic imaging during preparation of overt speech or hand movements in tasks designed to be e

262 n related to language production (sentential overt speech production-Speech task) and activation rela

263 ech may ultimately reflect a special type of overt speech.

264 Pax8-Cre/GR(fl/fl) mice did not exhibit an overt spontaneous phenotype.

265 -cell function in youth with newly diagnosed overt (stage 3) type 1 diabetes is unknown.

266 odynamic signals in the absence of a task or overt stimulation are used to infer neural activity.

267 inical cardiac dysfunction in the absence of overt structural abnormalities.

268 alcium dysregulation in dys-1 worms precedes overt structural phenotypes (e.g., mitochondrial, and co

269 These differences range from subtle to overt, suggesting that isolated epibulbar lacrimal gland

270 is excessive and as a result does not evoke overt sympathoexcitation.

271 latent period between immunization and EAE's overt symptom onset is characterized by distinct host re

272 Diseases are often diagnosed once overt symptoms arise, ignoring the prior latent period w

273 ven very early in the disease process before overt symptoms occur.

274 Prior to overt symptoms, muscle twitch rise and relaxation time c

275 ction and survival, even if they produce few overt symptoms.

276 Because many patients lack overt syndromic features, genetic testing plays an impor

277 ts are associated with iRBD and with pRBD in overt synucleinopathies.

278 ded primary outcome is phenoconversion to an overt synucleinopathy, and stratification features shoul

279 inopathy, as >80% will eventually convert to overt synucleinopathy.

280 the transition of preleukemic thymocytes to overt T-ALL.

281 state, progressing to insulin resistance to overt T2D-to explain the seemingly contradictory results

282 ty is not solely driven by simplification of overt task performance.

283 Overt tau pathology in the aged mice was accompanied by

284 participants sampled less when sampling was overt than when it was covert, suggesting that they avoi

285 develop normally, and adult mice exhibit no overt tissue abnormalities.

286 The vaccine was well tolerated and had no overt toxic effect.

287 ute ISR may explain why ISRIB does not cause overt toxic side effects in vivo.

288 mentation, clearance from circulation and no overt toxicity.

289 comprehensive screen, 5-HTP SR was devoid of overt toxicological effects.

290 57BL/6J-background, Lyst-mutant mice exhibit overt tremor phenotypes associated with loss of cerebell

291 increased hepatic lipid metabolism prior to overt tumor development.

292 ogress locoregionally or at distant sites as overt tumors.

293 e range, 6 to 21 years) with newly diagnosed overt type 1 diabetes to receive subcutaneous golimumab

294 ildren and young adults with newly diagnosed overt type 1 diabetes, golimumab resulted in better endo

295 ent a deleterious form of adaptation to more overt undernutrition (wasting).

296 M/F = 9/1; mean age = 42.1 years) displaying overt unilateral limbal stem cell deficiency complying w

297 nomonic driver-mutations that cannot explain overt variations in clinical outcome.

298 In overt videography of a post-graduate office, students sp

299 g mutations of ISG15 do not present with any overt viral phenotype, but are highly susceptible to env

300 c approach was implemented resulting in both overt (visible) and covert (near-infrared, NIR) properti