ライフサイエンスコーパス: overtly

1 e overexpressing hMT torsinA did not develop overtly abnormal motor behavior.

2 Moreover, while PVP-037 did not overtly activate THP-1 cells, it demonstrated broad inna

3 strate that the C-terminal mutation does not overtly affect APP processing and amyloid pathology.

4 lar knockdown of Cyp26a1 or Cyp26c1 does not overtly affect cardiovascular development, double Cyp26a

5 Notch does not overtly affect cell cycle entry or progression of CD4(+)

6 ducts (type I latency) that are not known to overtly affect cell growth.

7 Mutations in the B9 genes do not overtly affect cilia formation unless they are in combin

8 ld-type mice, this allele of Cdc25A does not overtly affect erythropoiesis; however, when this allele

9 ites in vitro, at concentrations that do not overtly affect mammalian host cells.

10 obal deletion of either Lrp5 or Lrp6 did not overtly affect osteoblast differentiation in the mouse e

11 d increase in postsynaptic activity does not overtly affect postsynaptic morphology but causes transi

12 progression in satellite cells, but did not overtly affect the myogenic program.

13 ult Muller glia in undamaged retina does not overtly affect their phenotype; however, when the retina

14 ), 25 mildly symptomatic (CDR = 0.5), and 33 overtly affected (CDR > 0.5) autosomal dominant Alzheime

15 Blood taken from overtly affected animals was assayed for antibodies to c

16 pithelial barrier function, however, was not overtly affected by brushing, despite the observed indiv

17 leading to differentiation of the CNS is not overtly affected by exposure to MeHg.

18 lveolar development during pregnancy was not overtly affected by loss of Gli2 function.

19 d with SNCA dosage and does not appear to be overtly affected by the presence of other genes in the m

20 owth of the falcipain 1 minus clones was not overtly affected, and they produced morphologically norm

21 desmin filaments in the cardiomyocytes were overtly affected, myofibril alignment was significantly

22 obe (IL) while the anterior lobe (AL) is not overtly affected.

23 remained constant, and MF alignment was not overtly affected.

24 s the formation of the atrial septum without overtly affecting atrial chamber formation.

25 d significantly reduced axon caliber without overtly affecting ensheathment.

26 gests that p19(ARF) can activate p53 without overtly affecting Mdm2 subcellular localization.

27 Like other ataxias, SCA2 most overtly affects Purkinje cells (PCs) in the cerebellum.

28 oximately one per genome per generation, not overtly altered across several DNA repair deficiencies o

29 llular and soluble CD127 expressions) is not overtly altered and remains activable in septic patients

30 illar collagen and the ECM proteome were not overtly altered when evaluated by quantitative mass spec

31 In contrast, heterozygous mice are overtly and histologically indistinguishable from contro

32 Cells derived from the overtly aphenotypical model of X-linked Emery-Dreifuss m

33 stined for programmed cell death but not yet overtly apoptotic.

34 IL-10-mediated inhibitory activity was not overtly associated with cytotoxicity or induction of apo

35 e hippocampal region is involved not just in overtly associative tasks but more broadly in the recoll

36 EMCV 30/87-infected macaques remained overtly asymptomatic for 45 days, despite extensive myoc

37 c failure, whereas the rest of the pigs were overtly asymptomatic for as long as 90 days postinfectio

38 B6.yaa mice are not overtly autoimmune, but the addition of Sle1, which cont

39 ble of recognizing self antigens but are not overtly autoreactive.

40 out work in other areas which demands a more overtly biomedical approach.

41 ovascular disease and significantly but less overtly by renal dysfunction.

42 attend to specific visual information either overtly, by making an eye movement to an object of inter

43 Antigen did not overtly cause action potential generation except in one

44 o Sham treatment, (56)Fe irradiation did not overtly change performance on tasks of visual discrimina

45 by TNF show reduced TEER, but do so without overtly changing their cell junctions, cell shape, or cy

46 While he does not overtly claim that social preferences are only by-produc

47 vidence from nonhuman primates and humans is overtly concerning, it lacks clinical verification.

48 number of structural differences in several overtly conserved homologous regions and more precisely

49 t that memory bystander CD8+ T cells may not overtly contribute to pathology in the absence of antige

50 esponse hand in an even larger proportion of overtly correct trials, revealing covert response impuls

51 tatin inhibited Ras processing without being overtly cytotoxic.

52 d injured soldiers under stressful and often overtly dangerous situations.

53 In summary, plasma Abeta is overtly decreased during the dementia stage of AD indica

54 Although overtly deleterious mutations in MMR genes can clearly b

55 nondeletional form of tolerance that is not overtly dependent on the prototypic Th1 and Th2 cytokine

56 In this experiment, participants overtly described autobiographical memories while underg

57 lations suggested that each mutation was not overtly destabilizing.

58 ic ovine PrP expressed in Drosophila was not overtly detrimental to the flies.

59 w concentrations of proteinase K, it was not overtly detrimental to the flies.

60 weaning, the male Nkx2.2-repressor mice are overtly diabetic and all Nkx2.2-repressor transgenic mic

61 Male mice became overtly diabetic at ~5 weeks of age, whereas female mice

62 and developed early hyperglycemia, with 85% overtly diabetic by 6 months.

63 vated blood glucose levels at birth and were overtly diabetic by weaning.

64 several therapies have successfully treated overtly diabetic mice.

65 ls induced chimerism without causing GVHD in overtly diabetic NOD mice conditioned with anti-CD3/CD8

66 ontinuous oral FTY720 (3 mg/kg) treatment in overtly diabetic NOD mice led to complete reversal of di

67 Overtly diabetic NOD mice received intravenous injection

68 In a pilot study, overtly diabetic NOD mice were cured by co-transplantati

69 Transient treatment of overtly diabetic NOD mice with ALS and exendin-4 achieve

70 Treatment of overtly diabetic NOD mice with anti-lymphocyte serum (AL

71 ycemia and immune tolerance to beta cells in overtly diabetic NOD mice, and none have demonstrably en

72 purified from the pancreatic lymph nodes of overtly diabetic NOD mice, mcDCs break peripheral T cell

73 to diabetes transferred by splenocytes from overtly diabetic NOD mice.

74 s incapable of preventing islet rejection in overtly diabetic NOD recipient mice.

75 itates regeneration of beta-cell function in overtly diabetic nonobese diabetic (NOD) mice.

76 A(+) patients but not in control subjects or overtly diabetic patients, suggesting that inflammation

77 was administered late during pathogenesis to overtly diabetic recipients.

78 lucose and glycosylated hemoglobin and seven overtly diabetic subjects were studied as were six nondi

79 uced obesity caused Skp2(-/-) mice to become overtly diabetic, because beta cell growth in the absenc

80 on only became manifest when subjects became overtly diabetic.

81 By 26 weeks of age, IDMs are overtly diabetic.

82 ge, 40% of these double heterozygotes become overtly diabetic.

83 e scanner to assess the ability to recognize overtly different intensities of disgust.

84 ns not favoring differentiation, they do not overtly differentiate but still activate expression of m

85 l fates generally fail to migrate and do not overtly differentiate.

86 Three of these neurons are overtly dimorphic and identify a male-specific neuropil

87 Infection was detected in overtly diseased and seemingly healthy animals.

88 5 when many tissues are assembling, does not overtly disrupt development as assessed by proteomic ana

89 cortical network activity, however, without overtly disrupting the balance of excitation and inhibit

90 The anatomy of the cerebellum is not overtly disturbed, and excitatory synaptic transmission

91 within hindbrain structures will produce an overtly dystonic animal.

92 riment, they could observe the choices of an overtly efficient player.

93 ants (23 female/17 male) who constructed and overtly elaborated on recent and remote memories in resp

94 The overtly electrostatic character of HA binding in Lyve-1

95 tive during wakeful rest when people are not overtly engaged with a sensory stimulus or externally or

96 -resistant focal epilepsy were instructed to overtly explain, in a sentence, 'what is in the image (s

97 hose with and those without current comorbid overtly expressed irritability/anger.

98 ld allow a habit to exist without ever being overtly expressed, if the prepared habitual response is

99 nce of morphologically distinct stages, from overtly featureless endoderm, through organ primordia to

100 osage forms were collected both covertly and overtly from 12 hospitals and 25 private or community ph

101 and connectivity patterns while participants overtly generated words according to nonmnemonic (phonem

102 Unlike many pathogens that are overtly harmful to their hosts, Mycobacterium tuberculos

103 The time required to overtly heal wounds was similar in fibrinogen-deficient

104 umonia and abscess-forming melioidosis in an overtly healthy host failing to clear Burkholderia pseud

105 Unlike overtly healthy Y3 mice, all Y3/CD103(-/-) mice rapidly

106 n at predicted Mendelian frequencies, appear overtly healthy, and contain normal numbers and frequenc

107 leaving the ICU for complex surgical cases, overtly high-risk patients, or the treatment of severe p

108 Evening types had overtly higher 24 h urinary epinephrine and morning plas

109 gmatised groups are currently the targets of overtly hostile evaluation and treatment by others (e.g.

110 -old ZDF rats in comparison with 12-week-old overtly hyperglycemic animals and, as controls, Zucker l

111 Blood glucose levels rose to overtly hyperglycemic levels in the obese group, stabili

112 he storage protein knockdown (SP-) seeds are overtly identical to the wild type, maturing to similar

113 nitial goal of this study was to define when overtly identifiable VSMCs were first associated with th

114 hough the items presented were identical and overtly identified in each task.

115 gic bronchopulmonary aspergillosis (ABPA) in overtly immunocompetent and atopic individuals, respecti

116 sorders in the PyN synthetic pathway are not overtly immunodeficient militate against this hypothesis

117 The mutation did not, however, overtly impact CD4+ T cell proliferation or differentiat

118 Deletion of Acly exon 14 in mice did not overtly impact development or metabolic physiology nor d

119 iver foci in X-CGD and iNOS KO mice was also overtly impaired at wk 2.

120 mal in 63%, borderline decreased in 15%, and overtly impaired in 22%.

121 or activity were additionally more common in overtly impaired mutation carriers.

122 rs can diminish T(reg) cell function without overtly impairing T effector cell responses or inducing

123 e and was likely the reason why BP increased overtly in these animals.

124 y of the canonical inflammasome but does not overtly increase risk of infection observations or radic

125 We found that antibiotic treatment did not overtly increase the parasite burden but significantly l

126 is often out of proportion to the amount of overtly infarcted tissue, and how decreased delivery of

127 lically diverse and overall not cytotoxic or overtly inflammatory in EEC; however, these bacteria can

128 oninflammatory, nonreplicating antigen or an overtly inflammatory replicating antigen, CD8(+) cytotox

129 saturation", a phenomenon whereby the use of overtly intense RF fields overwhelms the cross-relaxatio

130 ified stepwise during analysis, this did not overtly interfere with the SERS signals.

131 dents such as mice and rats, the dLGN is not overtly laminated, the retinal terminals from the two ey

132 ong with regions that will eventually become overtly lesion containing and areas of remyelination.

133 inue to blatantly dehumanize certain groups, overtly likening them to animals, with important implica

134 against tumor formation but is disabled when overtly malignant cells emerge.

135 rker is known to distinguish borderline from overtly malignant neoplasms.

136 emonstrate transformation of human ECs to an overtly malignant phenotype.

137 e these barriers and promote intermediate or overtly malignant tumors along distinct progression traj

138 cal Rb-negative cells appear and progress to overtly malignant tumors earlier.

139 the spectrum of malignancy from low grade to overtly malignant.

140 with acute lymphoblastic leukemia rarely are overtly malnourished, which makes this population ideal

141 has been applied to many simple, monogenic, overtly Mendelian human traits, with great success.

142 Although not overtly morphologically complex, molecular investigation

143 ficient Spanish-Basque bilinguals while they overtly name pictures in a mixed-language context.

144 ural signals of 34 human subjects (26 males) overtly naming 134 images from four semantic object cate

145 and non-native speakers of English who were overtly naming pictures of objects and reading their wri

146 ansion has evolved into a neoplastic-like or overtly neoplastic disorder, perhaps contributing to its

147 Furthermore, in overtly NOD mice, these cells are able to significantly

148 urine encephalomyelitis virus, and they made overtly normal Ab responses to a variety of antigens.

149 Secretin receptor-deficient mice are overtly normal and fertile; however, synaptic plasticity

150 Adult punc-deficient mice were overtly normal and had normal hearing.

151 mice lacking Rac1 or RhoA in podocytes were overtly normal and lived to adulthood.

152 These mice showed overtly normal cardiac structure/function under the basa

153 b1 hypomorphic mice are viable, fertile, and overtly normal despite weakened mitotic checkpoint activ

154 ice lacking one copy of the Map2k7 gene were overtly normal in a variety of behavioural tests, these

155 uration, and heavy chain class switching are overtly normal in A-myb-deficient mice.

156 one partially silenced Nmnat2 allele, remain overtly normal into old age, we now report that Nmnat2 c

157 ams from line D nurse their pups and display overtly normal mammary development, line A shows some im

158 alities with perinatal lethality, viable and overtly normal Tet1/Tet2-deficient mice were also obtain

159 eta-deficient mice were viable, fertile, and overtly normal well into adulthood, but displayed a 80%

160 increase in Th2 cytokine production but were overtly normal with respect to parasite infection and pa

161 h the expected Mendelian frequency, appeared overtly normal, and were fertile.

162 Conditionally mutant Dab2(-/-) mice are overtly normal, but have reduced clathrin-coated pits in

163 le a CPEB knockout (KO) mouse is sterile but overtly normal, embryo fibroblasts derived from this mou

164 While mice deficient in this domain are overtly normal, mice lacking Ron signaling have an alter

165 e, which were viable, fertile, and otherwise overtly normal, showed an increase in basal ERK1/2 phosp

166 Even though Nemp1 knockout (KO) mice are overtly normal, they display a pronounced splenomegaly.

167 ugh complexin 2 knockout (Cplx2-/-) mice are overtly normal, they show significant abnormalities in c

168 Mutant mice were overtly normal, viable, and fertile on the C57BL/6 backg

169 lpha 1A/C knockout (KO) mice were viable and overtly normal.

170 Homozygous knockout mice are overtly normal.

171 B- and T-cell development are overtly normal.

172 Mice homozygous for a Herc4 mutation are overtly normal; however, overall the males produce litte

173 ed concrete noun and generating verbs either overtly or covertly in response to the auditorily presen

174 ch centre on questions about whether studies overtly or covertly perpetuate genetic determinism, gene

175 providing an attachment substratum for more overtly pathogenic organisms such as Porphyromonas gingi

176 otential, from commensal to opportunistic to overtly pathogenic.

177 stort discussion of many topics that are not overtly political, including behavioral genetics and evo

178 and multiplicities, the observed fraction of overtly polyclonal heterotypic adenomas was significantl

179 alyses that relate the observed frequency of overtly polyclonal heterotypic tumors to the geometry of

180 en these 2 regions during passive viewing of overtly presented affective stimuli unrelated to trauma

181 he adaptation of motor commands that are not overtly produced.

182 -181a resulted in maturation of T cells that overtly reacted toward these erstwhile positively select

183 xes develop into mature T cells that are not overtly reactive to those same complexes.

184 genetic background, mutant heavy chains were overtly recessive and hypomorphic: each was able to subs

185 levels of religiosity, even after excluding overtly religious values.

186 rable to legal challenges and that would not overtly rely upon biblical literalism.

187 the specific sites of virus assembly without overtly removing it from the cell surface and that lipid

188 either attentively listened to the dialogue, overtly repeated (i.e., shadowed) attended speech, or pe

189 f similar activation increases in tasks that overtly require manipulation by instructing participants

190 ith the A11 or T22 antibodies, respectively, overtly rescued working memory.

191 e investigated the policy that humans use to overtly sample information in a perceptual decision task

192 However, this region is not overtly segmented in amphioxus, raising the question of

193 Multiple studies highlighted the overtly self-reactive T cell repertoire in the diabetes-

194 st, only a small proportion of AC units were overtly sensitive to any statistical features.

195 n areas that directs saccadic eye movements, overtly shifting both gaze and attention from position t

196 Young infants learn about the world by overtly shifting their attention to perceptually salient

197 ndothelial cell (EC) specification, which is overtly similar to the ability of Wnt signaling to direc

198 PSC and cancer cell metabolism are overtly similar, with metabolite levels influencing epig

199 ized on advances in fMRI denoising to employ overtly spoken recall.

200 r inflammatory cells, and resident cells can overtly stimulate nerve endings, cause long-lasting chan

201 mbers are reduced, these self-ligands become overtly stimulatory and cause naive T cells to prolifera

202 bscribe to white supremacist ideology, which overtly supports hate against Arab/Middle Eastern Muslim

203 iruses, and influenza B viruses but were not overtly susceptible to infection with human seasonal H3N

204 these cells to dystonic-like movements in an overtly symptomatic animal model.

205 a genetic model of primary dystonia that is overtly symptomatic, and link torsinA hypofunction to ne

206 ities in spatially distributed brain regions overtly synchronize in narrow frequency bands is critica

207 ernibly respond to sensory input and are not overtly task-modulated.

208 inth Schistosoma mansoni, the Th response is overtly Th2-like, creating an environment rich in IL-4.

209 atients do not retain the ability to respond overtly to command and it is becoming increasingly accep

210 These COX-2 and ODC inhibitor drugs were not overtly toxic at the doses used when administered to mic

211 In contrast, an overtly toxic concentration of cadmium (50 microM) rapid

212 Unlike many pathogens that are overtly toxic to their hosts, the primary virulence dete

213 be formation at concentrations that were not overtly toxic, as demonstrated by 3-(4,5-dimethylthiazol

214 pressing SV40T, hTERT and N-ras exhibited an overtly transformed phenotype; forming very large coloni

215 NOD mice, autoantibody-positive (AA(+)) and overtly type 1 diabetic (T1D) patients during the progre

216 ass switching and Ab affinity maturation are overtly unaltered.

217 g a pattern of double segment periodicity in overtly unsegmented tissue.

218 e 620 adults older than 60 years with acute, overtly unstable ankle fracture.

219 Here, fMRI participants (N = 40) overtly (verbally) recalled memories for ~2 min periods.

220 matic tricuspid regurgitation and may not be overtly visualized by echocardiography.

221 880 bacillary units, all of the rabbits were overtly well until they were sacrificed at 33 weeks.

222 to be angry with others and to express anger overtly, were not.

223 he C. elegans Skp2 ortholog, skpt-1, appears overtly wild type with the exception of an impenetrant g

224 hose patients who followed commands, whether overtly with behavior or covertly with functional neuroi