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1 ppropriate or not inappropriate (to evaluate overuse).
2 significant morbidity, and limit antibiotic overuse.
3 f a local population to minimise underuse or overuse.
4 nd nonfinancial strategies to reduce albumin overuse.
5 soil and groundwater pollution and pesticide overuse.
6 her a single episode of trauma or repetitive overuse.
7 hospitalization and is linked to antibiotic overuse.
8 d overall, whereas BS demonstrates continued overuse.
9 y, which may have the benefit of reducing GC overuse.
10 fibrosis, such as those induced with chronic overuse.
11 not be a reliable indicator of the extent of overuse.
12 increased risk of future extreme salbutamol overuse.
13 pulations may, in part, be due to procedural overuse.
14 onists, in a preclinical model of medication overuse.
15 se procedures has raised questions regarding overuse.
16 to demonstrate an association with acidifier overuse.
17 areas: screening, diabetes, depression, and overuse.
18 iated with performance on depression care or overuse.
19 underuse of medicines and leads to potential overuse.
20 ources as "cheap" or "free" encourages their overuse.
21 reductions in adverse outcomes, can indicate overuse.
22 this population, this practice may represent overuse.
23 policy interventions to reduce antimicrobial overuse.
24 ex; these effects are enhanced with forelimb overuse.
25 levers for eliminating medical underuse and overuse.
26 inpatient admission, suggesting large-scale overuse.
27 ately, but harmful when applied routinely or overused.
28 he above 5 centres CS was therefore probably overused.
29 or control were: short acting bronchodilator overuse [2.129 (2.091; 2.164)], days-off due to asthma [
30 , patients had 7.0% lower odds of antiemetic overuse (95% CI, 4.4%-9.5%) during the 6 months after th
31 standardized price), and a direct measure of overuse-advanced imaging for prostate cancer at low risk
32 380 UTI), nearly half (49.1%) had antibiotic overuse after discharge (56.9% pneumonia; 38.7% UTI).
33 prehensive metric to characterize antibiotic overuse after discharge among hospitalized patients trea
34 ospital-level association between antibiotic overuse after discharge in patients treated for pneumoni
37 dity or mortality, CS have been increasingly overused almost everywhere, both in high and low-income
38 Heart Association guidelines, IE prophylaxis overuse among negligible-risk patients and underuse amon
44 antibiotic targets risk promoting antibiotic overuse and antibiotic-associated harms for this subset
46 teral damage to the human microbiome through overuse and broadening spectrum, which has likely been t
51 re are serious concerns about the widespread overuse and misuse of antibiotics contributing to increa
53 lobal health threat and is often linked with overuse and misuse of clinical and veterinary chemothera
54 ceted efforts focusing on all three types of overuse and multiple conditions should be considered to
56 creases in cost of colonoscopy, evidence for overuse and studies demonstrating missed cancers have le
57 Despite the public attention to antibiotic overuse and the specter of antimicrobial-resistant patho
61 tations at the workshop that highlighted the overuse and underuse of screening, treatments, and techn
62 ntinue to debated, and studies point to both overuse and underuse of this operation in the management
65 nding of the system-level factors that drive overuse and underuse, as well as the various incentives
68 in order to better understand when IUCs are overused and inform the development of methodologically
70 k for infection, the avoidance of antibiotic overuse, and early deescalation policies are key to achi
73 owever, primary tumor resection may still be overused, and current treatment practices lag behind evi
74 t CRC screening is simultaneously underused, overused, and misused and that adequate patient-provider
77 emia, but not glucose intolerance or alcohol overuse as significant risk factors that deserve further
78 bservers believe that cancer chemotherapy is overused at the end of life, there are no published data
79 ider knowledge of guidelines may help reduce overuse, but despite awareness of the guidelines, physic
80 provide a donor infrastructure, and to limit overuse by defining risk and region adapted indications
81 significantly reduce medical ICU antibiotic overuse by earlier modification or cessation of antibiot
83 ients with individual preferences and needs; overuse can also be measured indirectly through examinat
84 cutely at sufficient quantities and repeated overuse can lead to addiction and deleterious effects on
89 suspected health risks related to fertilizer overuse, contributed to the negative image that inorgani
93 rtion of patients discharged with antibiotic overuse, defined as: unnecessary antibiotic use, excess
99 mediate/major resections, does not result in overuse for benign indications and some of the 2009 -con
101 rends, determinants, and costs of antiemetic overuse from January 1, 2008, through March 31, 2015.
102 trol (ACQ-5 >/= 1.5) or 'extreme' salbutamol overuse (> 32 salbutamol actuations/24-h period).
103 e is not without consequence, and carbapenem overuse has contributed to the emergence of carbapenem-r
104 gh nephrotoxicity and ototoxicity, and their overuse has led to the development of resistance to impo
115 Our data highlight a differential medication overuse headache risk profile for the ditan and gepant c
117 tors for chronic migraine such as medication-overuse headache, temporomandibular disorders, obstructi
125 ntimicrobial resistance is due to antibiotic overuse in agriculture and overprescription in medicine.
127 ffer from underuse in high-risk patients and overuse in average to moderate-risk patients, based upon
128 antagonists in eligible patients as well as overuse in settings in which therapy may be harmful.
134 d without a proper indication and frequently overused in critical care units, resulting in many compl
140 used VH gene segment in intact mice, also is overused in this plasmid assay, 15 to 30 times that of a
141 FG-3019 or pamrevlumab) reduces established overuse-induced muscle fibrosis in a clinically relevant
143 al details of major representative acute and overuse injuries characteristic to pediatric athletes wi
149 o be aware of the clinical manifestations of overuse injuries, to prescribe current recommended treat
161 spite the challenges, the high prevalence of overuse is well documented in high-income countries acro
162 the poststroke brain, using both a forelimb overuse manipulation that models a clinical neurorehabil
172 (aOR 4.11 [95% CI 1.37-12.38]); followed by overuse of acidifier for dissolving brown heroin prior t
173 Patients with chronic daily headache and overuse of analgesics, triptans, or other acute headache
175 ria leads to a life-threatening emergency or overuse of antibiotics and a high-rate occurrence of ant
184 with approaches to counseling families about overuse of antibiotics, teen pregnancy, hyperactivity, v
185 ted with empirical antibiotics, resulting in overuse of antibiotics, which promotes antimicrobial res
189 eclassification of stroke risk could prevent overuse of anticoagulants in very low stroke risk patien
192 ce settings-have the potential to reduce the overuse of antimicrobials and thereby reduce antimicrobi
193 Further interventions to reduce misuse and overuse of antimicrobials in high-consumption population
195 sues have emerged that need to be addressed: overuse of arrhythmia monitoring among a variety of pati
196 r the SMART regimen would reduce the risk of overuse of beta agonist, reduce the likelihood of patien
202 well-identified causes such as hand hygiene, overuse of catheters, and to a lesser extent, the airbor
204 Although practice aids adaptations, early overuse of cells adjacent to the site of injury might le
205 ccess health care system, we found potential overuse of chemotherapy among young and middle-aged adul
207 rence to colonoscopy guidelines could reduce overuse of colonoscopy and associated healthcare costs.
210 not exacerbate cardiovascular problems from overuse of diuretics or inotropes because of the unusual
212 13 Choosing Wisely (CW) campaign discouraged overuse of expensive antiemetics in patients with low ri
213 ial for unwarranted behavior changes and the overuse of health care resources in response to direct-t
214 n this Series have outlined how underuse and overuse of health-care services occur within a complex s
215 ncrease D-dimer specificity and may decrease overuse of imaging procedures and overdiagnosis of PE.
219 received treatment unnecessarily; there was overuse of intravenous immunoglobulin (IVIg) as first-li
223 , multiple research groups have rejected the overuse of N50 and sought to develop more informative me
224 d to a NICU, which raises the possibility of overuse of neonatal intensive care in some newborns.
225 underused cost-effective care or reduce the overuse of new and expensive treatments may not always m
227 s with treatment of substance use disorders, overuse of opioid medications, concerns with the structu
229 well as to environmental concerns regarding overuse of OPs, allowing significant reduction of use wi
230 ents with chronic migraine-like headache and overuse of pain medication improve after detoxification,
232 rippling opioid epidemic, spurred in part by overuse of prescription opioids by adults 25 to 64 years
233 h underuse of long-term control medications, overuse of quick-relief inhalers, and a significant numb
234 care costs encourage initiatives that avoid overuse of resources and identify opportunities to promo
242 In community practice, there is substantial overuse of surveillance colonoscopy among low-risk subje
245 ng autoantibodies remains a concern, as does overuse of tests for antineutrophil cytoplasmic autoanti
246 eloped nations are attributable, in part, to overuse of tests, treatments, and procedures that provid
247 chanism of decreased pain associated with an overuse of the degenerated joint has been referred to as
248 s after FL-SMC lesions, we found that forced overuse of the impaired forelimb during the first 7 days
249 the adult brain is more vulnerable to forced overuse of the impaired forelimb during the first 7 days
251 appear to be vulnerable to prolonged forced overuse of the impaired forelimb throughout the first 15
262 contributor to growing demand, and possible overuse, of peripherally inserted central catheters (PIC
266 etric to prompt investigation into potential overuse or underuse of antimicrobials and to evaluate th
268 known about patterns or trends in antiemetic overuse or whether any change has occurred with the publ
270 oblems, which may be classified as underuse, overuse, or misuse, occur in small and large communities
271 ents directed at a novel therapeutic target, overuse phase II studies of FDA-approved agents, and fai
274 rent study explores the potential medication overuse risk of two novel therapeutic drug classes, name
276 ontaining opioids and barbiturates, caffeine overuse, stressful life events, depression, sleep disord
278 Low-risk intravenous chemotherapy agents had overuse that continued to decrease 6 months after the CW
279 es not, except in extreme cases of pesticide overuse that result in negative agricultural/economic co
282 aive rats via a mechanism involving receptor overuse.The current data support that, whereas D1LR-modu
285 g process, it can substantially decrease the overuse, underuse, and misuse of health care services.
287 ntage of patients discharged with antibiotic overuse varied five-fold among hospitals (15.9% [95% CI:
288 nds and factors responsible for chemotherapy overuse very near death and underutilization of hospice
289 The three-way kappa statistic to detect overuse was 0.52 for coronary revascularization and 0.51
291 a rhematologist with a history of repetitive overuse, weakness, pain and involuntary, end-range postu
292 rease was transitory: the odds of antiemetic overuse were 7.4% (95% CI, 4.6%-10.2%) higher than basel
294 rends, determinants, and costs of antiemetic overuse were estimated in cases stratified by risk for c
296 mpact of agriculture by eliminating nutrient overuse, while still allowing an approximately 30% incre
298 c upper extremity stress injuries related to overuse with a focus on anatomic location, patient histo