ライフサイエンスコーパス: overwhelming

1 ories of individuals in need too emotionally overwhelming.

2 However, the resulting deluge of data can be overwhelming.

3 or the remains being those of Richard III is overwhelming.

4 the number of guidelines and updates can be overwhelming.

5 This overwhelming abundance of cryptobenthic larvae fuels ree

6 proposed for addressing the challenge of the overwhelming abundance of genomic sequence and other bio

7 relative to the infecting bacterium and the overwhelming abundance of uninformative structural RNAs

8 ow that growth by dimers is preferred due to overwhelming accumulation of adsorbed dimers on the crys

9 viruses susceptible to error catastrophe, an overwhelming accumulation of mutations incompatible with

10 However, overwhelming activation and accumulation of neutrophils

11 botic thrombocytopenic purpura (TTP) whereas overwhelming activation of complement via an alternative

12 r trace silver extraction in the presence of overwhelming activities of (137)Cs via the autodepostion

13 One patient died from an overwhelming adenoviral infection before reconstitution

14 Owing to the overwhelming advantage in energy density, lithium-sulfur

15 tA or equivalent mutations that conferred an overwhelming advantage.

16 andard in critically ill patients due to its overwhelming advantages, was the only tool able to speci

17 ethylated CpGs at other gene regions, and by overwhelming age-related methylation in CpG islands and

18 pled algorithmic approaches to deal with the overwhelming amount of data generated by modern mass spe

19 high spatial-temporal resolution provides an overwhelming amount of data.

20 r technological solutions able to manage the overwhelming amount of high throughput genomic data need

21 Sensory environments often contain an overwhelming amount of information, with both relevant a

22 ally expanded in recent years, leading to an overwhelming amount of patient variants with high variab

23 ing machines, these must be selected from an overwhelming amount of raw data.

24 es displayed by humans in making sense of an overwhelming amount of sensory information cannot be exp

25 s for a target antibody in the context of an overwhelming amount of unrelated immunoglobins present i

26 mponents of the immune system as well as the overwhelming amounts of data can make it difficult to in

27 The presence of overwhelming amounts of information in our big-data era

28 Our brains operate on overwhelming amounts of information, and thus their effi

29 n in such a capricious environment can prove overwhelming and compromise one's ability to effectively

30 ice with HOXA10 gene disruption exhibited an overwhelming and fatal emergency granulopoiesis response

31 synthetic methodology toward heterocycles is overwhelming, and catalysis, in particular, as one of th

32 The literature on this subject is overwhelming, and no consensus has been reached, with a

33 ssively and express phenotypes indicative of overwhelming antigenic stimulus and tissue homing/cytoto

34 Although we also confirmed overwhelming association at the LOXL1 locus, the key SNP

35 SSA measurements are typically dominated by overwhelming background aerosol concentrations even in r

36 extracting rare stochastic events out of an overwhelming background using the highly sensitive CEI m

37 ion and compromises host defense, leading to overwhelming bacterial infection.

38 ponses employed by the host to deal with the overwhelming bacterial presence of the microbiota.

39 Previous randomised trials have shown an overwhelming benefit of mechanical thrombectomy for trea

40 up of 27 months, because the boundary for an overwhelming benefit with LCZ696 had been crossed.

41 Despite the overwhelming benefits of antiretroviral therapy (ART) in

42 Overwhelming, bipartisan support by voters exists for en

43 However, an overwhelming body of knowledge has accumulated in the fi

44 The overwhelming body of research on T regulatory cells (Tre

45 appearance and propagation of bacteria cause overwhelming cellular stress responses that induce apopt

46 noniterative at the module level remains an overwhelming challenge, which may account for the seemin

47 Considering the overwhelming changes that occurred during primate evolut

48 hylmercury inputs to the estuary by 25-200%, overwhelming climate-driven changes over the next decade

49 hes enable rapid reconstruction of TRNs, the overwhelming combinatorics of possible networks limits i

50 sage in nitrogen reduction reaction (NRR) as overwhelming competition from hydrogen evolution reactio

51 y assuming a tame solution and inaction from overwhelming complexity.

52 of the finite difference method can have an overwhelming computational cost in models with a high-di

53 rmance, people remember certain stimuli with overwhelming consistency.

54 The overwhelming contribution of diesel compared to gasoline

55 h late recovery from coma lacked evidence of overwhelming cortical injury but demonstrated prominent

56 Given the huge influence caused by the overwhelming COVID-19 pandemic affecting over three mill

57 Overwhelming data in both humans and mice reveal a clear

58 Overwhelming data suggest that oncogenic and neurodegene

59 Overwhelming data support the use of medical therapy as

60 However, mCRPC showed overwhelming de novo resistance to immune checkpoint blo

61 We identified an overwhelming decrease in the expression of anti-oxidant

62 To survive overwhelming demands on the proteasome arising during en

63 le this may be thought of as secondary to an overwhelming desire for drugs, it could equally well ref

64 differ greatly, ranging from asymptomatic to overwhelming disease and death, having available both an

65 Issues are discussed as related to the overwhelming dominance of social determinants on oral di

66 t cells showed that Bccip deletion caused an overwhelming down-regulation of genes involved in mitoti

67 ndation of this model is the theory that the overwhelming driver of cancer risk is mutations.

68 ee densities at finer scales, as well as the overwhelming effect of humans across most of the world.

69 We also observe an overwhelming effect of the established TCF4 locus.

70 count after therapy initiation highlight the overwhelming effectiveness of antiretroviral therapy in

71 he data and safety monitoring board owing to overwhelming efficacy.

72 utational analysis of a large dataset can be overwhelming, especially for novices.

73 Considering the overwhelming evidence about the effectiveness of primary

74 There is overwhelming evidence both in vivo and in vitro that tra

75 Despite overwhelming evidence for D2 receptors (D2Rs) in maintai

76 moma, although there was significant but not overwhelming evidence for thyroid, parathyroid, lung, an

77 Importantly, overwhelming evidence gathered over recent years shows t

78 Overwhelming evidence has shown poor reproducibility and

79 Overwhelming evidence indicates that an ultrasonography-

80 Overwhelming evidence indicates that the pancreatic canc

81 In conclusion, there is overwhelming evidence linking the NLRP3 inflammasome and

82 While previously controversial, overwhelming evidence now suggests that increased reacti

83 Overwhelming evidence now supports the presence of a dee

84 ived comparatively little attention, despite overwhelming evidence of a pivotal role for the PAG in c

85 With overwhelming evidence of change in habitats, biologists

86 This is despite overwhelming evidence of its unique role in causing a wo

87 Recent genetic studies have provided overwhelming evidence of the involvement of microglia-re

88 Results showed overwhelming evidence of the paradox across lifetime and

89 Despite the overwhelming evidence showing the influence of sex or ob

90 However, the overwhelming evidence shows that the quality of reportin

91 Overwhelming evidence shows the critical role of glycoly

92 Overwhelming evidence supports the endosymbiosis theory

93 There is overwhelming evidence that G-protein-coupled receptors (

94 There is overwhelming evidence that ions are present near the vap

95 There is overwhelming evidence that leaf-internal isoprene increa

96 (13)C and (1)H NMR data provide overwhelming evidence that most UiO-66 organic linkers a

97 In disease states, there is overwhelming evidence that stress hyperlactataemia is a

98 There is now overwhelming evidence that the innate and adaptive branc

99 or analyzing the SOP fail to account for the overwhelming evidence that the wake/sleep transition is

100 timulate the immune system, and there is now overwhelming evidence that this drives chronic immune ac

101 Despite overwhelming evidence that transcriptional activation by

102 There is now overwhelming evidence to support lowering LDL-c (low-den

103 dogenous Neanderthal DNA is present among an overwhelming excess of recent human DNA.

104 There is now overwhelming experimental and clinical evidence that ath

105 IT may be less effective when a tumor lacks "overwhelming" expression of a single target such as EGFR

106 Finally, the complex nature of plasma was overwhelming for HD1, but we define conditions for the t

107 ions based on molecular profiling results is overwhelming for many oncology clinicians and researcher

108 Designing mechanical metamaterials is overwhelming for most computational approaches because o

109 cant.] Upper-bound estimates suggest that an overwhelming fraction (90%) of these losses is due to th

110 exacerbating socioeconomic inequalities and overwhelming fragmented health systems.

111 The present findings indicate that the overwhelming GABAergic drive present at the DMV is prima

112 promising medical technology to address the overwhelming global aging, which requires advanced micro

113 ill still lead to COVID-19 epidemics rapidly overwhelming health systems, with substantial excess dea

114 emergency departments (EDs) and potentially overwhelming health systems.

115 ts exciting scientific challenges as well as overwhelming health, equity, and economic benefits.

116 rus, has spread rapidly throughout the world overwhelming healthcare systems.

117 ontrol of an illegal trade in which there is overwhelming historical evidence of its complicity.

118 This overwhelming historical success makes it very difficult

119 , but in the clinical setting are limited by overwhelming host material and ultra-low target frequenc

120 es a novel function of the H4R preventing an overwhelming immune reaction by engagement of a negative

121 This overwhelming immune response is regulated by damage-asso

122 a, this intensification is likely to involve overwhelming increases in wet spell intensity.

123 In contrast to the overwhelming infection seen in the mice challenged with

124 ighly susceptible to fatal ehrlichiosis, had overwhelming infection, and developed extensive tissue i

125 of STAT1 mutation is ultimately fatal due to overwhelming infection.

126 cent deaths of several migrant children from overwhelming infections in United States detainment cent

127 nia, a condition linked to increased risk of overwhelming infections, remain largely unknown.

128 ages, leading to early onset, recurrent, and overwhelming infections.

129 ls at lesional sites was concomitant with an overwhelming infiltration of CD8(+) T-cells that demonst

130 nvading pathogens is essential to preventing overwhelming inflammation and sepsis that are symptomati

131 vation syndrome (MAS) is an acute episode of overwhelming inflammation characterized by activation an

132 ntributes to tissue healing and recovery but overwhelming inflammation is associated with postoperati

133 a novel macrophage population that controls overwhelming inflammation on one hand but is also necess

134 his might be important to avoid sustained or overwhelming inflammation, our data suggest that a negat

135 Here, we show that VML injury incites an overwhelming inflammatory and fibrotic response that lea

136 Controlling the overwhelming inflammatory reaction associated with polym

137 induces organ failure and is accompanied by overwhelming inflammatory response and impairment of mic

138 yte and macrophage lineage cells, leading to overwhelming inflammatory responses.

139 sly overlooked annual CO(2) sinks due to the overwhelming influence of these weathering reactions.

140 eroxia, but this effect is less prominent if overwhelming injury is induced by the combination of hyp

141 and attractive target for modulation of the overwhelming innate immune response.

142 Although an overwhelming insecticidal effect against Anopheles steph

143 Proteomics revealed overwhelming interactions of endogenous VCP with ribosom

144 red to simulate cellular crowding, introduce overwhelming interferences to mass spectrometry (MS) ana

145 h is predominantly focused on healthcare, an overwhelming investment in developing drugs and treatmen

146 ons for fluorescent dye molecules due to the overwhelming isoenergetic fluorescence signal.

147 ment has to be tightly controlled to prevent overwhelming leukocyte infiltration, activation, and, co

148 e parasite species, resulting in potentially overwhelming levels of complexity.

149 sence of adequate compensatory regeneration, overwhelming liver damage can cause acute liver failure

150 olving hundreds of introns and genes with an overwhelming loss of IR in erythroid cells and MKs compa

151 Overwhelming lung inflammation frequently occurs followi

152 Rationale: In addition to the overwhelming lung inflammation that prevails in COVID-19

153 zero positive end-expiratory pressure caused overwhelming lung injury, subsequently shown by others t

154 The overwhelming majority (97%) of alpha-satellite DNA is fo

155 ase I-hypersensitive sites and show that the overwhelming majority are populated by well-spaced sites

156 ch incorrect candidate locations consumes an overwhelming majority of a modern read mapper's executio

157 rved as the archetypal organism on which the overwhelming majority of biochemical characterizations o

158 asive and metastatic stages accounts for the overwhelming majority of cancer deaths.

159 An acceptable formation model for the overwhelming majority of chondrules, however, has not be

160 The overwhelming majority of clustered CTCF sites colocalize

161 y of EBP1 in human (Homo sapiens) cells, the overwhelming majority of EBP1 interactors are part of ri

162 To date, however, the overwhelming majority of experimentally realized single-

163 a subset of these frequencies that drive the overwhelming majority of gas transport in fractured rock

164 Furthermore, an overwhelming majority of genetic variants within or near

165 oss-comparison of assemblies showed that the overwhelming majority of HGT candidates in the Boothby e

166 From 2006 to 2009, the overwhelming majority of hospitalizations or ED presenta

167 hed active variants up to 2,800-fold from an overwhelming majority of inactive ones at approximately

168 stablished that aerobactin accounted for the overwhelming majority of increased siderophore productio

169 o Mycobacterium tuberculosis (MTB), with the overwhelming majority of infected individuals not develo

170 Although the overwhelming majority of intertwines between the parenta

171 nto the human genome, we discovered that the overwhelming majority of intronic and exonic RE are expr

172 emerged in all 3 serovars and is seen in the overwhelming majority of isolates, while resistance to t

173 However, an overwhelming majority of liquids possess anisotropy in p

174 Unfortunately, spectral selectivity of the overwhelming majority of metamaterials that are made of

175 The overwhelming majority of Msp2 variants expressed during

176 However, Ral, and the overwhelming majority of mutant oncogenic K-Ras, are dev

177 Though the overwhelming majority of natural processes occur far fro

178 The overwhelming majority of nonphysicians adopted the "good

179 tes, and can be readily implemented when the overwhelming majority of nucleic acids in a specimen der

180 low, supporting a nonstroke etiology to the overwhelming majority of original events.

181 The overwhelming majority of participants in current genetic

182 al-regulated kinase inhibitor treatment, the overwhelming majority of patients eventually acquire res

183 conclusion, COL7A1 harbored mutations in the overwhelming majority of patients with dystrophic epider

184 rvention within 6 months of insertion in the overwhelming majority of patients.

185 g and MNase HS regions) may give rise to the overwhelming majority of phenotypic variation, greatly n

186 Small-scale farmers - the overwhelming majority of poultry producers in low-income

187 However, the overwhelming majority of previously reported temperature

188 mber of sequenced genomes rapidly grows, the overwhelming majority of protein products can only be an

189 The overwhelming majority of pseudoviruses fully released GF

190 e acetylation marks have been described, the overwhelming majority of regulatory genomics studies foc

191 s electric activity/asystole is growing, the overwhelming majority of research in risk stratification

192 irect response to metabolic deficit, yet the overwhelming majority of research on the biology of food

193 To date, the overwhelming majority of researches have focused on chem

194 The overwhelming majority of respondents thought that incide

195 The overwhelming majority of scientific knowledge is publish

196 y the male population, which constitutes the overwhelming majority of smokers in China.

197 The overwhelming majority of sports-related sudden deaths oc

198 The overwhelming majority of studies aiming to understand ub

199 However, the overwhelming majority of studies demonstrate the presenc

200 However, the overwhelming majority of studies examining this relation

201 the active sites of oxidoreductases, yet the overwhelming majority of studies on small-molecule mimic

202 II PI3K in PI(3,4)P(2)-driven function, the overwhelming majority of the lipid accumulates through d

203 preservation solution after NMP removes the overwhelming majority of third-party allogeneic pRBCs, b

204 The overwhelming majority of UTIs are caused by uropathogeni

205 Because the overwhelming majority of variants are present in only a

206 Moreover, the overwhelming majority of variants, both somatic and germ

207 In dogs, an overwhelming majority of visually-responsive cortex exhi

208 s and assemble into homomeric complexes, the overwhelming majority of which (>96%) are symmetric.

209 Foods contain microorganisms, the overwhelming majority of which are nonpathogenic, some a

210 ated in patients with advanced fibrosis, the overwhelming majority of whom had NASH.

211 LAC was absent in an overwhelming majority of women with exclusively early re

212 ng variants identified per individual can be overwhelming, making it prudent to focus on noncoding re

213 Although Cannabis contains an overwhelming milieu of terpenoids, only a limited number

214 injury coexist, providing the basis for the overwhelming morphologic and clinical heterogeneity of A

215 In order to make sense of the overwhelming mutational data and capitalize on this clin

216 Furthermore, these communities have an overwhelming need and desire for point-of-use water trea

217 n seeds arrived in extremely high densities, overwhelming niche-based mortality factors.

218 Kenya was reported on 12 March 2020, and an overwhelming number of cases and deaths were expected, b

219 The overwhelming number of genetic alterations identified th

220 Despite the overwhelming number of human long non-coding RNAs (lncRN

221 The overwhelming number of new catalysts and conditions rece

222 Due to the overwhelming number of passenger mutations in the human

223 Although there is an overwhelming number of research articles and reviews foc

224 This financial burden is an overwhelming obstacle for Haiti's poorest citizens, and

225 clearance arises for many reasons, including overwhelming of the clearance machinery, disruptions at

226 We propose that overwhelming or disrupting the chaperone function of PZP

227 gainst chronic infections from progressively overwhelming other antibody specificities.

228 s the major contributor to Pb contamination, overwhelming other potential local and transboundary sou

229 s opioids works to close this gate, reducing overwhelming pain generated by parallel pathways.

230 erior population survival during a simulated overwhelming pandemic.

231 e essential, but the scale of the task risks overwhelming parliament and the civil service.

232 etween giving explicit information while not overwhelming patients and being realistic while remainin

233 Here, based on overwhelming patterns of genetic, morphological, and eco

234 ddicted tumors in vitro and in vivo leads to overwhelming phospho-STAT1 activation, turning on its tu

235 s and clinical presentation of patients with overwhelming postsplenectomy infection (OPSI).

236 dity and mortality in these patients are the overwhelming postsplenectomy sepsis and development of l

237 k were IgA isotype, in stark contrast to the overwhelming predominance of IgG isotype Env-specific B

238 ents with upper GI tumors was thwarted by an overwhelming predominance of low ERCC1 mRNA expression.

239 standing feature of these assemblages is the overwhelming predominance of monothalamids, a group ofte

240 Fish from another population showed an overwhelming preference for red irrespective of what was

241 markers onto the tree of Bacteria shows the overwhelming presence of diderm phyla and the non-monoph

242 f prokaryotic type were characterized by the overwhelming presence of omega-3 C18 polyunsaturated fat

243 the search for novel approaches to blunt the overwhelming pro-allergic Th2 response, we evaluated the

244 evidence that complement activation provokes overwhelming pro-inflammatory responses, whether or not

245 that most septic patients do not die from an overwhelming proinflammatory immune response but in an i

246 The overwhelming proportion of false positives results in re

247 Aggregation does not arise because of overwhelming proteasome-mediated degradation but because

248 tory disease causing thousands of deaths and overwhelming public health systems.

249 Overwhelming pulmonary inflammation and endothelium disr

250 Given the overwhelming quantity of information available from the

251 Also notable was the overwhelming reduction in mast cell transcripts, potenti

252 poisoning may be related to interrupting or overwhelming relevant regulatory or signaling process(es

253 l system, antimicrobial use does not lead to overwhelming resistance, as is typical in clinical setti

254 This coding scheme emphasizes the overwhelming role of the inferior olive in generating sa

255 Although the results revealed overwhelming satisfaction with the IACUC administrative

256 portunities associated with translating this overwhelming scientific progress into real clinical bene

257 idity with which the virus struck was indeed overwhelming, scientists throughout the world have been

258 unoglobulins, the patient ultimately died of overwhelming sepsis.

259 mmunomodulating therapy, the patient died of overwhelming sepsis.

260 also affect leading-edge sex ratios, perhaps overwhelming sex-biased dispersal.

261 The overwhelming size and rapid growth of the biomedical lit

262 Overwhelming spectroscopic and chemical evidence support

263 ior is often conceptualized as a response to overwhelming stress.

264 Despite overwhelming structural similarity between the periplasm

265 elationship can be established because of an overwhelming success in ablation.

266 The overwhelming success of exome- and genome-wide associati

267 s an intriguing feature and critical for the overwhelming success of higher plants.

268 Despite the overwhelming success of vaccines in preventing infectiou

269 ecently, 5 major randomized trials showed an overwhelming superior benefit of combining endovascular

270 ns introduced into the cytosol outcompete an overwhelming supply of constitutively generated peptides

271 We find overwhelming support for a long-term decline across all

272 We find overwhelming support for agriculture being introduced to

273 ral snakes in both space and time, providing overwhelming support for Batesian mimicry.

274 among the three distinct analyses, providing overwhelming support for the monophyletic status of subf

275 isrupt traditional health care operations by overwhelming system resource capacity but also create op

276 In severe trauma, overwhelming systemic inflammation can result in additio

277 Sepsis is typically triggered by an overwhelming systemic inflammatory response to pathogens

278 Overwhelming systemic inflammatory responses may suppres

279 educed Treg recruitment to the kidney and an overwhelming TH1 immune response, with an aggravated cou

280 The evidence is now overwhelming that partially assembled nucleosome states

281 The evidence is now overwhelming that psychiatric disorders are "polygenic"-

282 nts in a dose- and motor-dependent manner by overwhelming the ability of Aurora B to mediate error co

283 ific variation in these responses was large, overwhelming the average community response.

284 ting condensation level (LCL) with elevation overwhelming the effects of decreasing total column wate

285 g the lowest LUMO level recorded for an NDI, overwhelming the formative tetracyanoquinodimethane (TCN

286 ce 2009, the economic recovery increased TF, overwhelming the influence of improved emissions intensi

287 , and complexity of environmental change are overwhelming the intrinsic capacity of corals to adapt a

288 een sometimes described as "compelling" and "overwhelming", there are limitations that existing studi

289 ors in response to challenging situations or overwhelming threats can become activated pathologically

290 thus have the potential to contribute to the overwhelming thrombo-inflammation in COVID-19, and the i

291 mmunosuppressive mediators that help prevent overwhelming tissue damage.

292 continuously released novel packages can be overwhelming to the immunologist with limited computatio

293 ntations of significant sequence hits can be overwhelming to the user.

294 scovery of new phages and help interpret the overwhelming unknown sequences in the viral metagenomics

295 e energy and environmental issues due to the overwhelming use of fossil fuels.

296 There is an overwhelming variety of LAMP indicators in the literatur

297 associated with death at an early age due to overwhelming viral infection (complete STAT1 deficiency)

298 e full spectrum of research grapple with the overwhelming volume of data being generated daily and a

299 because reference-induced biases can become overwhelming when dealing with divergent strains.

300 ourth, 'Missing the big picture', identifies overwhelming workload and fixation on specific parameter