ライフサイエンスコーパス: oviduct

1 f the apoptosis-inducing factor Trail in the oviduct.

2 he stream that guides sperm migration in the oviduct.

3 ease from the ovary and its passage into the oviduct.

4 tus induces fluid flow to guide sperm in the oviduct.

5 onse that did not prevent reinfection of the oviduct.

6 cy of late apoptotic/dead neutrophils in the oviduct.

7 bservations inside the large, muscular avian oviduct.

8 tected within the egg/cumulus complex in the oviduct.

9 ital tract, but fail to cause disease in the oviduct.

10 is specifically expressed in females in the oviduct.

11 nd applied to eggs as they progress down the oviduct.

12 nce of allurin in the serosal capsule of the oviduct.

13 t contact with eggs as they move through the oviduct.

14 and the passage of early embryos through the oviduct.

15 concurrently with the apoptotic index of the oviduct.

16 al activity and restrict expression to avian oviduct.

17 e oviduct, and then persists apically in the oviduct.

18 two key reproductive tissues, the uterus and oviduct.

19 e ovary as well as on eggs isolated from the oviduct.

20 s induced eightfold by estrogen in the chick oviduct.

21 l aspect of the epithelium in the uterus and oviduct.

22 and adult lung, choroid plexus, testis, and oviduct.

23 passage of pre-implantation embryos down the oviduct.

24 hronic gestational hypoxia on the developing oviduct.

25 maternal-gamete/embryo cross-talk within the oviduct.

26 s such as airways, brain ventricles, and the oviduct.

27 and physical cues provided by the egg or the oviduct.

28 and suggesting it is expressed in the adult oviduct.

29 une cell infiltration were determined in the oviducts.

30 CR-positive samples were from the uterus and oviducts.

31 on-induced swelling of the oocyte within the oviducts.

32 eonates had ovaries they lacked a uterus and oviducts.

33 cilitates the spread of both variants to the oviducts.

34 which regulates muscle contraction in locust oviducts [21]; and the FMRF amide dromyosuppressin, whic

35 Few eggs are detected in the oviduct after stimulation with gonadotropins, and no two

36 Gestational hypoxia-exposed oviducts also showed evidence of decreased mitochondrial

37 h following estrogen treatment in the chick oviduct, an extremely estrogen-responsive reproductive t

38 embryos spend the first few days within the oviduct and are transported to the uterus, where they im

39 aled constitutive and inducible NOS in human oviduct and cumulus (the cellular layer investing the oo

40 oth muscle cells of reproductive tracts, the oviduct and ductus epididymis.

41 ating gonadal steroid control, typical of an oviduct and egg specific gene.

42 icit significant chronic inflammation of the oviduct and fails to induce hydrosalpinx.

43 implantation embryo floats freely within the oviduct and is capable of developing into a blastocyst i

44 ique pattern of expression in the uterus and oviduct and its regulation by estrogen, a principal repr

45 on, and there was a significant reduction in oviduct and mesosalpinx pathology at late time points.

46 behavior required for progression along the oviduct and penetration of the zona pellucida.

47 of Wnt7a that mediates the patterning of the oviduct and proper differentiation of the uterus.

48 Oviduct and somatic ovarian telomere length declined mor

49 sociation between the hormonal milieu in the oviduct and sperm detachment; therefore, we tested direc

50 al processes such as oocyte transport in the oviduct and sperm penetration.

51 mRNA is expressed almost exclusively in the oviduct and that its expression is increased 2.5-fold by

52 tracts, with the uterus anteriorized towards oviduct and the vas deferens anteriorized towards epidid

53 lacking estrogen receptor alpha (ERalpha) in oviduct and uterine epithelial cells have impaired ferti

54 as preferentially recruited to the upper GT (oviduct and uterine horn) over the lower GT (cervical-va

55 The changes observed in the oviduct and uterus are accompanied by a postnatal loss o

56 rtile because of abnormal development of the oviduct and uterus, both of which are Mullerian duct der

57 lower levels of neutrophil chemokines in the oviducts and decreased production of neutrophil chemokin

58 sozymes show defects in transport within the oviducts and in binding to zonae pellucidae.

59 e ovaries, followed by egg movement down the oviducts and the deposition of eggs onto the substratum.

60 s progressively as the egg moves through the oviducts and the uterus.

61 of the Mullerian ducts leads to retention of oviducts and uteri in males.

62 ucing male pseudohermaphrodites that possess oviducts and uteri.

63 During infection, Il1a(-/-) oviducts and uterine horns exhibited reduced neutrophil

64 ent mice showed reduced dilation in both the oviducts and uterus.

65 strogen-treated and estrogen-withdrawn chick oviducts and was subjected to differential display analy

66 roductive tissues (male hemipenes and female oviduct) and brain.

67 g fusion, migration from the uterus into the oviduct, and binding to the egg zona pellucida.

68 tor binding in the cockroach hindgut, locust oviduct, and fruit fly crop are similar.

69 ntaneous muscle contractions of the hindgut, oviduct, and heart.

70 pathway were regulated by estrogen in mouse oviduct, and inhibition of this pathway in a whole ovidu

71 ghly stage-specific manner in the uterus and oviduct, and its expression is restricted to the surface

72 ssful ovulation, transport of the COC to the oviduct, and its fertilization, depend on the interactio

73 o expressed in lung, eye, intestine, uterus, oviduct, and male reproductive tract.

74 vel of acute inflammation in the endocervix, oviduct, and mesosalpingeal tissues than in infected wil

75 ium in the region between the uterus and the oviduct, and then persists apically in the oviduct.

76 s exist in the utero-vaginal junction of the oviduct, and there is growing evidence that sperm storag

77 lting two-cell embryos were transferred into oviducts, and live mice were born.

78 ge of oocytes from the ovary into the narrow oviducts, and osmotic pressure caused by hydration-induc

79 in the uterus; proliferative lesions of the oviduct; and persistent vaginal cornification.

80 development and differentiation of the chick oviduct are exquisitely dependent upon estrogen, this se

81 The muscle cells surrounding the oviducts are multinuclear with highly organized sarcomer

82 pairs, the male ejaculatory duct and female oviduct, are known to be developmentally homologous.

83 alian preimplantation embryos develop in the oviduct as individual entities, and can develop and surv

84 ooperation may assist sperm passage into the oviduct as well as sperm-egg interactions.

85 ated epithelial cells lining the bronchi and oviduct, as well as in the developing spermatocytes in t

86 alpinx even when directly delivered into the oviduct at a high dose.

87 ferentiate CBF in different locations of the oviduct at different post-conception stages.

88 s compared with controls in both ovaries and oviducts at 6 mo.

89 e affects the transcriptional network in the oviducts at a specific stage of the estrous cycle.

90 greater numbers of viable chlamydiae in the oviducts at lower inoculating doses, and the number of o

91 njunctivitis in the cervix, endometrium, and oviducts at various times following a primary intravagin

92 m not only resulted in more infection in the oviduct but also stimulated more inflammatory infiltrati

93 sion of ER mRNA was prominent in most of the oviduct but not in the luminal epithelium.

94 ovaries, dTdc2 mutants release eggs into the oviducts but are unable to deposit them.

95 patches in the region between the uterus and oviduct, but is confined to the basal aspect of the epit

96 implantation embryos within the intact mouse oviduct by a simple electroporation method, and result i

97 non-oviduct tissue and in estrogen-deprived oviduct by a strong repressor site located from -130 to

98 sting that a rapid but transient invasion of oviduct by chlamydial organisms can prevent the developm

99 d to the GI tract even when delivered to the oviduct by intrabursal inoculation.

100 g oogenesis and delivering the oocyte to the oviduct by ovulation.

101 Elevated protease activity in cKO oviducts causes premature degradation of the zona pelluc

102 ds, present the first in vivo mapping of the oviduct CBF in its native context, and demonstrate the a

103 of progesterone to induce sperm release from oviduct cell aggregates.

104 gions were made and transfected into primary oviduct cell cultures.

105 beta production-capable TLR expressed by the oviduct cell lines, we were not able to determine whethe

106 n vitro could mimic in vivo sperm binding to oviduct cells and increase sperm longevity, we immobiliz

107 stimulated the release of 48% of sperm from oviduct cells or 68% of sperm from an immobilized oviduc

108 Sperm were allowed to bind to oviduct cells or an immobilized oviduct glycan and then

109 the progesterone-induced sperm release from oviduct cells or immobilized glycan.

110 purified BMP-7 induces apoptosis in primary oviduct cells.

111 ine endometrium, as well as epithelia of the oviduct, cervix, and vagina.

112 n the number of CD4, CD8, and B cells in the oviduct compared to the number of these cells at the sam

113 ious studies suggested that a barrier in the oviduct confines sperm and Acp36DE to a limited area nea

114 erse the uterus but do not progress into the oviduct, contributing to the infertility of fertilin bet

115 amide hydrolase (FAAH) in mouse embryos and oviducts creates locally an appropriate "anandamide tone

116 amide hydrolase (FAAH) in mouse embryos and oviducts creates locally an appropriate "anandamide tone

117 t, and inhibition of this pathway in a whole oviduct culture system resulted in a decreased embryo tr

118 were significantly protected from end point oviduct damage and fibrosis.

119 alpha in WT mice prevented infection-induced oviduct damage, further supporting a key role for IL-1al

120 ubsequent growth of OA synaptic sites at the oviduct, demonstrating that seminal proteins can contrib

121 y enhanced the incidence of hydrosalpinx and oviduct dilatation compared to those of TNF-alpha(-/-) m

122 ence of oviduct dilatation; however, reduced oviduct dilatation was observed for "controllers," i.e.,

123 ncluding the development of hydrosalpinx and oviduct dilatation.

124 Animals in both groups developed evidence of oviduct dilatation; however, reduced oviduct dilatation

125 tivation contributes to pathogen control and oviduct disease independently of caspase-1 activation.

126 smid-deficient strains are protected against oviduct disease upon challenge with virulent C. muridaru

127 g assays demonstrated that regression of the oviduct during estrogen withdrawal involves apoptosis, w

128 ydial burden was similar in WT and Il1a(-/-) oviduct during peak days of infection, levels of IL-1bet

129 cy and absolute number of neutrophils in the oviducts during acute infection.

130 The deduced primary sequence of the chicken oviduct ecto-ATPDase indicates a protein of 493 amino ac

131 -ATPDase are similar to those of the chicken oviduct ecto-ATPDase that we have previously purified an

132 tudy of a purified ecto-ATPDase, the chicken oviduct ecto-ATPDase, with respect to ATP and ADP, and a

133 hows only minor differences from that of the oviduct ecto-ATPDase.

134 a unique design of CRISPR donor with the new oviduct electroporation technique i-GONAD.

135 Although slightly larger than the 80-kDa oviduct enzyme, the two ecto-ATPDases are nearly identic

136 rface of ciliated epithelial cells of: lung, oviduct, epididymis, ductus deferens, and seminiferous t

137 like receptor 3 (TLR3) function in the human oviduct epithelial (hOE) cell line OE-E6/E7 in order to

138 the critical pattern recognition receptor in oviduct epithelial (OE) cells that is stimulated during

139 For this report a murine oviduct epithelial cell line was derived in order to det

140 The infected oviduct epithelial cell lines also secreted the immunomo

141 Oviduct epithelial cell lines infected with C. muridarum

142 We generated cloned murine oviduct epithelial cell lines without viral or chemical

143 Utilizing cloned murine oviduct epithelial cell lines, we previously identified

144 ute phase cytokines by C. muridarum-infected oviduct epithelial cell lines.

145 Because murine oviduct epithelial cells express TLR3 but not TLRs 4, 7,

146 mydia-induced IFN-beta synthesis in infected oviduct epithelial cells implicates a novel ligand that

147 infection induces IFN-beta synthesis in the oviduct epithelial cells in a TRIF-dependent manner.

148 arked only a fraction of ovarian surface and oviduct epithelial cells in wild-type tissues.

149 As expected, oviduct epithelial cells infected by Chlamydia muridarum

150 eased production of neutrophil chemokines by oviduct epithelial cells infected with CM3.1 in vitro.

151 for infection-induced IFN-beta secretion by oviduct epithelial cells remains to be determined.

152 C. muridarum-infected murine oviduct epithelial cells secrete the inflammatory cytoki

153 gene (STING) protein in HeLa cells and mouse oviduct epithelial cells significantly decreased IFN-bet

154 nt-negative TLR3 mutants, and TLR3-deficient oviduct epithelial cells to show that the IFN-beta secre

155 n the Chlamydia-induced IFN-beta response in oviduct epithelial cells, we used small interfering RNA,

156 macrophage cell line and in primary chicken oviduct epithelial cells.

157 of IFN-beta production by Chlamydia-infected oviduct epithelial cells.

158 The oviduct epithelial lines did not secrete IFN-beta in res

159 these in vitro studies predict that infected oviduct epithelium contributes significantly to host inn

160 on of a large number of embryos in the mouse oviduct, eventually leading to pregnancy failure.

161 Incubation of human sperm with oviduct explants induced sperm protein S-nitrosylation r

162 irect effects on preimplantation embryos via oviduct expression of embryotrophic cytokines.

163 , and wild-type embryos transferred into cKO oviducts fail to develop normally unless rescued by conc

164 to the gastrointestinal tract while inducing oviduct fibrotic blockage or hydrosalpinx.

165 ulated oocytes that can be fertilized in the oviduct (Figure 1).

166 ted with increased organism ascension to the oviduct following the intrauterine inoculation.

167 vipositional embryonic arrest in the hypoxic oviduct for different lengths of time depending on the m

168 tibody and T cell responses that protect the oviduct from pathology despite a lack of sterilizing imm

169 elicited recall responses that protected the oviduct from pathology despite low-level reinfection of

170 s unknown if these signals are necessary for oviduct function in supporting fertilization and preimpl

171 d to bind to oviduct cells or an immobilized oviduct glycan and then challenged with progesterone, wh

172 ct cells or 68% of sperm from an immobilized oviduct glycan.

173 l hypoxia leads to accelerated ageing of the oviduct in adulthood.

174 l hypoxia leads to accelerated ageing of the oviduct in early adulthood and they help us understand h

175 senchyme disrupted the normal coiling of the oviduct in the knockout embryo, resembling the phenotype

176 f CD4 cells to the upper genital tract (GT) (oviducts) in comparison to the lower GT (cervix) during

177 led an important role of the interactions of oviduct infection with inflammatory responses in chlamyd

178 CBA/J mice developed a delayed and extensive oviduct infection.

179 The severity of oviduct inflammation and dilatation resulting from these

180 ntravaginal inoculation, suggesting that the oviduct inflammation can be induced by plasmid-independe

181 nts, despite their ability to activate acute oviduct inflammation, are attenuated in inducing tubal f

182 with the fact that eggs progressing down the oviduct initially show evidence of allurin being incorpo

183 n embryo development and passage through the oviduct into the uterus are prerequisites for implantati

184 which correlated with a rapid but transient oviduct invasion by C. muridarum with a peak infection o

185 monstrates that the function of BMP-7 in the oviduct involves the induction of apoptosis and that est

186 eri-conceptual environment in the developing oviduct is affected by gestational hypoxia, then this co

187 The tubular gland of the chicken oviduct is an attractive system for protein expression a

188 her sterilizing immunity at the level of the oviduct is essential for protection because of the possi

189 etory cells in the luminal epithelium of the oviduct, is displayed on the ciliary layer and then mech

190 a swimming pattern of mammalian sperm in the oviduct, is essential for fertilization in vivo.

191 osited at mating or insemination reaches the oviduct isthmus, where sperm are retained and thereby fo

192 the apical epithelial surface at the uterine-oviduct junction.

193 We observe that the oviduct lacks a clear demarcation from the anterior uter

194 med within the isthmic regions of the female oviducts, leading to a conjecture in the literature that

195 a preadaptation to the fetal feeding on the oviduct lining of viviparous caecilians.

196 , we found significantly more neutrophils in oviduct lumen of A/J mice on days 7 and 10, which correl

197 6, CSF3, and CXCL2 were reduced in Il1a(-/-) oviduct lysates.

198 at adequate live chlamydial infection in the oviduct may be necessary to induce hydrosalpinx.

199 have a direct role in sperm-zona binding or oviduct migration; alternatively, the effects on these f

200 agonist on the cockroach hindgut and locust oviduct, mimicked the effect of dromyosuppressin on the

201 virulent variant, could be isolated from the oviducts more often and in greater numbers than the atte

202 The posterior VNC contains Ilp7+ oviduct motoneurons, whose innervation and morphology ar

203 We report further that oviduct muscle relaxation can be induced by activating O

204 of CB1 and beta2-adrenergic receptors in the oviduct muscularis implies that a basal endocannabinoid

205 identified a mating-dependent relaxation of oviduct musculature, for which ovulin is a necessary and

206 tor (RBF) was originally isolated from avian oviduct nuclear matrix.

207 mation of hydrosalpinx-a surrogate marker of oviduct occlusion and infertility.

208 iggered oviductal fluid secretion clears the oviduct of debris, lowers viscosity, and generates the s

209 ar Pullorum colonized both the ovary and the oviduct of hens and led to 6% of laid eggs being infecte

210 Infusion of hCG into the oviduct of steroid-hormone-treated ovariectomized baboon

211 ation was induced by chlamydial infection in oviducts of C3(-/-) mice, explaining why the C3(-/-) mic

212 were significantly fewer neutrophils in the oviducts of caspase-11-deficient mice, supporting the ob

213 In the present study, we show that the oviducts of female rats exposed to chronic hypoxia in ut

214 Finally, the oviducts of infected infertile mice showed evidence of c

215 ts (Cas9 mRNA and guide RNA (gRNA)) into the oviducts of pregnant females 1.5 d post conception, foll

216 At 3 and 6 mo, ovaries and oviducts of recuperated offspring had increased mitochon

217 less invasive when delivered directly to the oviduct on day 7 after inoculation.

218 Similar to human STIC, the gene-edited oviduct-on-a-chip, exhibited loss of cell polarization a

219 ex, tympanum diameter, presence of distended oviducts or eggs for females, and testes length and sper

220 did intercaruncular endometrium, myometrium, oviduct, ovary, fetal bladder, or fetal kidney.

221 terone (P<0.001) and is reduced in regressed oviducts (P<0.001) demonstrating gonadal steroid control

222 athogenesis of Chlamydia trachomatis-induced oviduct pathological sequelae is not well understood.

223 cing Chlamydia-specific CD8(+) T cells cause oviduct pathological sequelae.

224 al clearance rates but significantly reduced oviduct pathology (hydrosalpinx) compared to that of wil

225 nd pathology in the uterine horns but normal oviduct pathology after infection.

226 the murine genital tract but does not elicit oviduct pathology because it fails to activate Toll-like

227 ronic infection in MyD88 KO mice resulted in oviduct pathology comparable to that of WT mice, increas

228 tested and found to display no reduction in oviduct pathology compared with control mice.

229 ta has been implicated in the development of oviduct pathology during Chlamydia muridarum genital inf

230 ay, in IL-1beta secretion and development of oviduct pathology during genital chlamydial infection.

231 its upstream activator, ASC, contributes to oviduct pathology during mouse genital Chlamydia muridar

232 on-CD8(+) cells cooperates to induce optimal oviduct pathology following genital chlamydial infection

233 n-CD8(+) T cells contribute significantly to oviduct pathology following genital chlamydial infection

234 cient mice) had no significant difference in oviduct pathology from control mice.

235 more, IFNAR(-/-) mice developed less chronic oviduct pathology in comparison to that in WT mice.

236 N-beta has been implicated as an effector of oviduct pathology resulting from genital chlamydial infe

237 ither WT or TNFR1 KO CD8(+) T cells restored oviduct pathology to WT levels in both KO groups.

238 rophil infiltration, and reduced severity of oviduct pathology upon C. muridarum genital infection.

239 ns of Chlamydia muridarum are protected from oviduct pathology upon challenge with wild-type C. murid

240 The contribution of IL-1alpha to oviduct pathology was more dramatic than observed in mic

241 uridarum infection but significantly reduced oviduct pathology, compared with WT animals.

242 -1R-deficient mice had significantly reduced oviduct pathology, which was associated with decreased n

243 ect to both chlamydial clearance and reduced oviduct pathology.

244 n earlier than control mice and develop less oviduct pathology.

245 m, CM3.1, does not induce the development of oviduct pathology.

246 earance of infection and in the mediation of oviduct pathology.

247 idarum clearance, greater dissemination, and oviduct pathology.

248 mmatory mediators and development of chronic oviduct pathology.

249 ce, while C57BL/6 mice are more resistant to oviduct pathology.

250 ng the observed decrease in the incidence of oviduct pathology.

251 rther supporting a key role for IL-1alpha in oviduct pathology.

252 absence of both caspase-1 and caspase-11 on oviduct pathology.

253 Comparison of granulosa, uterus and oviduct PGR-dependent genes showed almost complete tissu

254 Motile cilia in the mammalian oviduct play a key role in reproduction, such as transpo

255 that extracellular vesicles (EVs) within the oviduct play important roles in mediating this developme

256 The oviduct plays a central role in early development as the

257 mechanism of restricted sperm entry into the oviduct rather than in sperm-egg interaction.

258 In mammals, the oviduct regulates sperm functions, such as Ca(2+) influx

259 deleterious anamnestic T cell response upon oviduct reinfection.

260 , the mechanisms mediating regression of the oviduct remain unknown.

261 trogen-mediated cellular function within the oviduct remains unclear.

262 No bursa membrane is formed, and the oviduct remains uncoiled.

263 h levels of mRNA of vesicular markers in the oviduct segments where eggshell mineralization occurs.

264 ng genital Chlamydia muridarum infection and oviduct sequelae.

265 cal granules, nor is it the mouse homolog of oviduct-specific glycoprotein.

266 esults indicate that bovine sperm binding to oviduct suLe(A) retains sperm for reservoir formation an

267 ed in various tissues including lung, brain, oviduct, testis, and embryonic kidney.

268 infiltration and cytokine production in the oviduct than the intravaginal inoculation, suggesting th

269 is secreted from the upper two thirds of the oviduct that includes the pars recta and the proximal pa

270 loops in the uterus and in the upper common oviduct that relax and constrict throughout sperm storag

271 dence exists regarding effects of BPA on the oviduct, the placenta, and pubertal development.

272 in estrogen-responsive tissues such as chick oviduct, the regulation of chMRP1 gene expression is con

273 becomes impermeable as it proceeds down the oviducts; the process is complete by the time the egg is

274 In the hypoxia-exposed oviducts, there was upregulation of mitochondrial-specif

275 alter the lipid microenvironment within the oviduct, thereby affecting sperm motility.

276 cilia and their activity in the lumen of the oviduct through tissue layers represents a major challen

277 Ov is repressed in non-oviduct tissue and in estrogen-deprived oviduct by a str

278 um, IL-1R signaling plays a critical role in oviduct tissue damage.

279 illumination microscopy to optically section oviduct tissue from zebra finch Taeniopygia guttata fema

280 tory infiltration and cytokine production in oviduct tissue, suggesting that C5 may contribute to chl

281 ive chlamydial organisms were recovered from oviduct tissues of both C5(-/-) and C5(+/+) mice, sugges

282 Uterine and oviduct tissues were assessed for transcription of MMP g

283 al-vaginal tissues) and upper genital tract (oviduct tissues) to increasing inoculating doses.

284 gest that IRF members also repress Ov in non-oviduct tissues.

285 nation of Crisp protein expression in the Xt oviduct using RT-PCR showed that of five documented Xt C

286 loping Mullerian duct that gives rise to the oviduct, uterus and upper region of the vagina of the fe

287 In females, Mullerian ducts develop into the oviduct, uterus, cervix and upper vagina, whereas Wolffi

288 the emergence of distinct cell types in the oviduct, uterus, cervix and vagina and is dependent upon

289 of the Mullerian ducts, the primordia of the oviducts, uterus and upper vagina.

290 ctive tract organs of mammals, including the oviducts, uterus, cervix and upper vagina, are derived f

291 organisms were directly inoculated into the oviduct via an intrabursal injection, which was accompan

292 ducts that constitute a major portion of the oviduct wall.

293 , and expression levels in the magnum of the oviduct were constant over at least 16 months in transge

294 n of the bacteria from the endocervix to the oviduct, where an overly aggressive inflammatory respons

295 d to the tubular glands of the magnum of the oviduct, where egg white synthesis occurs, with around 1

296 sion of jeltraxin mRNA was restricted to the oviduct, which distinguishes it as the first serum-relat

297 arum developed visible hydrosalpinges in the oviduct while the remaining 13 did not, although all inf

298 How oocytes are transferred into an oviduct with a receptive environment remains poorly know

299 lia beat frequency (CBF) in the intact mouse oviduct with micro-scale spatial resolution.

300 utrophils were eliminated from the blood and oviducts with this treatment, immature neutrophils and h