ライフサイエンスコーパス: oxidative cleavage

1 enzyme and suggests a possible mechanism for oxidative cleavage.

2 iscoidol via cytochrome P450 (CYP)-catalyzed oxidative cleavage.

3 ring following removal of the C-24 carbon by oxidative cleavage.

4 e oxide was effective at both hydrolytic and oxidative cleavage.

5 cellulosic polysaccharides, and carry out C4 oxidative cleavage.

6 l-E)-beta-carotene following epoxidation and oxidative cleavage.

7 wo epoxides were detected as a result of the oxidative cleavage.

8 ](2+) clusters and O(2)-induced [4Fe-4S](2+) oxidative cleavage.

9 We demonstrate the unique oxidative cleavage activity of the CTB3 monooxygenase do

10 the tandem process between a Hock or Criegee oxidative cleavage and a nucleophilic addition onto the

11 results from a pre-equilibrium involving C-H oxidative cleavage and a subsequent rate-limiting beta-H

12 at modify double bonds of these compounds by oxidative cleavage and cis-to-trans isomerization.

13 of segmented polyurethanes (SPUs) to in vivo oxidative cleavage and hydrolysis constitutes a drawback

14 s to modify product compositions in both the oxidative cleavage and sulfide oxidation pathways are an

15 ne oxide (PO) ring-opening, homogeneous diol oxidative cleavage, and homogeneous aldehyde oxidation r

16 ndicate that H2 activation at 2 proceeds via oxidative cleavage at Ru with concomitant hydride transf

17 her functionalization including epoxidation, oxidative cleavage/Baeyer-Villiger oxidation, Riley oxid

18 lkyl aryl sulfones is quickly accompanied by oxidative cleavage by atmospheric O2, leading to the for

19 sion and transcriptional regulation, through oxidative cleavage by carotenoid oxygenases.

20 Asp and tRNAPhe, were used as substrates for oxidative cleavage by Fe.bleomycin to facilitate definit

21 s are biosynthesized from zeaxanthin through oxidative cleavage by the carotenoid cleavage dioxygenas

22 al dihydroxylation of the olefin with oxone, oxidative cleavage by the in situ-generated 3,4,5,6-tetr

23 an unusual functionalized skeleton caused by oxidative cleavage; compound 2 possesses an unprecedente

24 sp(3))-H oxidation, alkene isomerization and oxidative cleavage, consistently outperforming conventio

25 Bioinspired Cu(I)-induced oxidative cleavage decreases FRET between fluorescein do

26 olecular ene reaction to form the C ring, an oxidative cleavage followed by aldol condensation to rea

27 hylmagnesium iodide to Grundmann's enone 28, oxidative cleavage, functional group modifications leadi

28 Folates in vivo undergo oxidative cleavage, giving pterin and p-aminobenzoylglut

29 been exploited to demonstrate chemoselective oxidative cleavage in substrates containing two double b

30 of RNA in the absence of added metal ion and oxidative cleavage in the presence of Fe(2+) and O(2).

31 Folates undergo oxidative cleavage in vivo, releasing a pterin aldehyde

32 silicates-which are not redox active-induced oxidative cleavage indicates that surfaces acted as cata

33 to a substituted cycloheptenone by a tandem oxidative cleavage/intramolecular Horner-Wadsworth-Emmon

34 In ABA biosynthesis, oxidative cleavage is the first committed reaction and i

35 Formation of the gamma-lactone through the oxidative cleavage is used to assign stereochemistry of

36 The oxidative cleavage mechanism of Cu2-BPL-C6 was then eluc

37 cus utilizes a combination of hydrolytic and oxidative cleavage mechanisms to degrade cellulose.

38 therapeutic small molecule, is generated via oxidative cleavage of 1,1-dithiooxalate (DTO) photosensi

39 The aerobic oxidative cleavage of 1,2-diols using a heterogeneous ca

40 Subsequent oxidative cleavage of 16a-d then provided tetrahydrofura

41 Oxidative cleavage of 19 (RuCl(3)/NaIO(4)) followed by e

42 This enzyme catalyzes the oxidative cleavage of 2,6-dichlorohydroquinone in the ca

43 G by PM followed by irreversible PM-mediated oxidative cleavage of 3-DG.

44 ABA is synthesized via an oxidative cleavage of 9-cis epoxy-carotenoids, the first

45 recombinant chicken BCO2 also catalyzes the oxidative cleavage of 9-cis-beta-carotene and the non-pr

46 Specifically, oxidative cleavage of [Me(2)Si(C(5)Me(4))(2)]M(RH) is fa

47 Only two of these six sites involved oxidative cleavage of a 5'-G.Pyr-3' sequence, but three

48 a key control step in ABA biosynthesis--the oxidative cleavage of a 9-cis xanthophyll precursor to f

49 radation of 1,2-dichloroethane (1,2-DCA) via oxidative cleavage of a C-H bond (Pseudomonas sp. strain

50 PhnZ is notable for catalyzing the oxidative cleavage of a carbon-phosphorus bond using Fe(

51 nt hormone abscisic acid is derived from the oxidative cleavage of a carotenoid precursor.

52 This approach utilizes the oxidative cleavage of a variety of beta-keto esters and

53 Oxidative cleavage of a variety of olefins to the corres

54 AI), to generate acetyl radicals through the oxidative cleavage of acetohydrazide, enabling efficient

55 re non-heme Fe(II) enzymes that catalyze the oxidative cleavage of alkene bonds in carotenoids, stilb

56 synthetic metal catalysts that allow for the oxidative cleavage of alkenes at an atmospheric pressure

57 Oxidative cleavage of alkenes in aerobic conditions sugg

58 The oxidative cleavage of alkenes is an integral process tha

59 dy of N-hydroxyphthalimide-catalyzed aerobic oxidative cleavage of alkenes is carried out employing d

60 we report an alternative approach to achieve oxidative cleavage of alkenes using nitroarenes and purp

61 The enzyme also catalyzed the oxidative cleavage of alpha-carotene, beta-cryptoxanthin

62 solation of highly reactive formylsilanes by oxidative cleavage of alpha-silyl glycols is presented.

63 gulator abscisic acid (ABA) is formed by the oxidative cleavage of an epoxy-carotenoid.

64 Oxidative cleavage of arachidonate (C(20)) and linoleate

65 testing of compounds that are generated upon oxidative cleavage of arachidonate and linoleate esters

66 The key step features an oxidative cleavage of aza-bicyclo[3.2.2]nonene 14, which

67 The Fe2+-mediated oxidative cleavage of BamHI occurs between residues Glu7

68 ir corresponding carbonyl derivatives to the oxidative cleavage of benzyl ethers, whereas 2 has been

69 The oxidative cleavage of benzylic and allylic C-H bonds usi

70 genase (Bcdo), the enzyme that catalyzes the oxidative cleavage of beta,beta-carotene into two retina

71 The oxidative cleavage of beta-carotene resulted in increase

72 he purified enzyme preparation catalyzed the oxidative cleavage of beta-carotene with a Vmax = 197.2

73 ation of apo-10'-carotenoids, suggesting the oxidative cleavage of both carotenoids at their 9',10'-d

74 The oxidative cleavage of C C double bonds with molecular ox

75 ones from R-CO-CHR-Ar through a simultaneous oxidative cleavage of C-C and C-H bonds using KO(t)Bu.

76 its superior activity towards photocatalytic oxidative cleavage of C-C bond for a series of lignin mo

77 pimerizations (methylmalonyl-CoA epimerase), oxidative cleavage of C-C bonds (extradiol dioxygenase),

78 bisperoxides with high selectivity over the oxidative cleavage of C=C bond that usually forms the ke

79 A photocatalytic method for the aerobic oxidative cleavage of C=C bonds has been developed.

80 The topic of this review is oxidative cleavage of carbohydrate polymers by lytic pol

81 species, which are also known to elicit the oxidative cleavage of carbon-boron bonds.

82 n under aqueous alkaline conditions promotes oxidative cleavage of carbon-carbon bonds in lignin olig

83 rotene 9',10'-oxygenase (BCO2) catalyzes the oxidative cleavage of carotenoids at the 9'-10' bond to

84 ses catalyze the non-heme iron(II)-dependent oxidative cleavage of catechols to 2-hydroxymuconaldehyd

85 lysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of crystalline polysaccharides such a

86 Oxidative cleavage of cycloalkene-1-carboxylates, made f

87 Free radical-induced oxidative cleavage of DHA-PC promoted by myeloperoxidase

88 rotene 15-15'-oxygenase (BCO1) catalyzes the oxidative cleavage of dietary provitamin A carotenoids t

89 on of amines in addition to facilitating the oxidative cleavage of dithioacetals and dithioketals.

90 r mechanism of action is believed to involve oxidative cleavage of DNA and possibly also RNA degradat

91 While oxidative cleavage of DNA was observed for Cu(2+)(aq) un

92 A new reagent for the oxidative cleavage of DNA, (1,4,7-trimethyl-1, 4,7-triaz

93 ee carbon carbohydrates possibly formed from oxidative cleavage of early glycation products are invol

94 provide evidence that ABA is synthesized by oxidative cleavage of epoxy-carotenoids (the "indirect p

95 nyl) dialdehydes 14 and 19 are accessible by oxidative cleavage of extensively substituted cyclohexen

96 onooxygenases (LPMOs) are known to carry out oxidative cleavage of glycoside bonds in chitin and cell

97 characterization of cellulose peroxygenase (oxidative cleavage of glycosidic bonds in cellulose) and

98 (LPMOs) are monocopper enzymes that catalyze oxidative cleavage of glycosidic bonds in polysaccharide

99 s are copper-dependent enzymes that catalyze oxidative cleavage of glycosidic bonds in polysaccharide

100 ccharide monooxygenases (LPMOs) catalyze the oxidative cleavage of glycosidic bonds in recalcitrant p

101 ) are copper-dependent enzymes that catalyze oxidative cleavage of glycosidic bonds using molecular o

102 to activate molecular oxygen for subsequent oxidative cleavage of glycosidic bonds.

103 suggests the steps in the LPMO mechanism for oxidative cleavage of glycosidic bonds.

104 me chromophore phytochromobilin involves the oxidative cleavage of heme by a heme oxygenase (HO) to f

105 nd iron acquisition in many pathogens is the oxidative cleavage of heme by heme oxygenase (HO), yield

106 The oxidative cleavage of heme by heme oxygenases (HOs) to f

107 The final step in releasing iron is the oxidative cleavage of heme by HemO.

108 These proteins catalyze oxidative cleavage of heme to CO and biliverdin, and rel

109 Heme oxygenases (HO) catalyze the oxidative cleavage of heme to generate biliverdin, CO, a

110 The oxidative cleavage of heme to release iron is a mechanis

111 ron acquisition strategies to include direct oxidative cleavage of heme-containing proteolytic fragme

112 xidation, ligand-free Heck macrocyclization, oxidative cleavage of indole, synthesis of contiguous st

113 Os) contribute to this process by catalyzing oxidative cleavage of insoluble polysaccharides utilizin

114 Oxidative cleavage of isoprene adducts 3j, 3k, 3l, and 3

115 Fe(II)/Fe(III) cofactor for the O2-dependent oxidative cleavage of its substrate.

116 only two known enzymes able to catalyze the oxidative cleavage of latex for biodegradation.

117 Surprisingly, BCO1 catalyzed the oxidative cleavage of lycopene to yield acycloretinal wi

118 azol-2-ylidene) has been synthesized by mild oxidative cleavage of Me3 SiSiMe3 using [(ITMe)2 Pd(0) ]

119 Oxidative cleavage of methoxy and methoxybenzene moiety,

120 myo-Inositol oxygenase (MIOX) catalyzes the oxidative cleavage of myo-inositol (MI) to give d-glucur

121 We show that alpha-AE will also catalyze the oxidative cleavage of N-acylglycines, from N-formylglyci

122 Oxalate oxidase (EC 1.2.3.4) catalyzes the oxidative cleavage of oxalate to carbon dioxide and hydr

123 Ozonolysis or oxidative cleavage of peracetylated allyl derivatives re

124 ctive chlorinating species promote selective oxidative cleavage of plasmalogens, liberating alpha-chl

125 ysaccharide monooxygenases (LPMOs) carry out oxidative cleavage of polysaccharides and are of major i

126 This chemistry may contribute to the oxidative cleavage of polyunsaturated fatty acyls that p

127 rotene 15,15'-oxygenase (BCO1) catalyzes the oxidative cleavage of provitamin A carotenoids at the ce

128 The discovery of oxidative cleavage of recalcitrant polysaccharides by ly

129 lysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of recalcitrant polysaccharides such

130 ly been shown to catalyze the O(2)-dependent oxidative cleavage of recalcitrant polysaccharides.

131 Hydrogen peroxide is a cosubstrate for the oxidative cleavage of saccharidic substrates by copper-c

132 hagocytes kill encapsulated microbes through oxidative cleavage of surface carbohydrates, releasing g

133 A chemoselective oxidative cleavage of synthetic gracilioether B, 11-epi-

134 An unusual selective oxidative cleavage of the (SS)-isomer was observed and t

135 everal important processes in plants, is the oxidative cleavage of the 11,12 double bond of a 9-cis-e

136 ng 4-oxo derivatives by isoform 1A2, and the oxidative cleavage of the acetyl ester of vitamin A (ret

137 ion-aldol reaction, followed by CAN-mediated oxidative cleavage of the aldol product.

138 nverted to gamma-hydroxy-beta-amino acids by oxidative cleavage of the alkyne.

139 Oxidative cleavage of the allylic amines furnishes the a

140 hiosemicarbazones that had been generated by oxidative cleavage of the appropriate pyruvic aldehyde d

141 low molecular weight carboxylic acids after oxidative cleavage of the aromatic bond with two vicinal

142 a(4)-1,2-azaborete complex and the selective oxidative cleavage of the B-N bond of the 1,2-azaborete

143 substituted cyclohexane that is generated by oxidative cleavage of the bicyclic sesquiterpene beta-tr

144 yketones by sequential allylic oxidation and oxidative cleavage of the bridging double bond at the B/

145 H(3)CN solutions of 3-OTf with O(2) leads to oxidative cleavage of the C(1)-C(2) and C(2)-C(3) bonds

146 ion of the hydroxy group as a THP acetal and oxidative cleavage of the C,C-double bond provided a sta

147 ound with a vanadium catalyst results in the oxidative cleavage of the C-C bond between the aryl ring

148 ey event in this transformation involves the oxidative cleavage of the C-C triple/double bond and the

149 s a means of facilitating the chemoselective oxidative cleavage of the C6-C7 bond.

150 e coupling of cinnamic acids with amines via oxidative cleavage of the C=C bond.

151 ment of low-molar-mass fragments obtained by oxidative cleavage of the capsular polysaccharide of Hae

152 -O-allyl purine nucleosides (13a and 15) via oxidative cleavage of the carbon-carbon bond to the corr

153 se that increases substrate accessibility by oxidative cleavage of the chitin chains.

154 ordination to form a C H sigma complex, (ii) oxidative cleavage of the coordinated C H bond to give a

155 Oxidative cleavage of the cyclic stereotetrads yields te

156 We were also able to show that oxidative cleavage of the cyclopentene 1,5-CH insertion

157 After oxidative cleavage of the double bond of 13 and reductio

158 bination with subsequent decarboxylation and oxidative cleavage of the double bond, allows the highly

159 o limonoid 2 by a sequence consisting of (1) oxidative cleavage of the exocyclic double bond, (2) ste

160 hydrate-based radical precursor, followed by oxidative cleavage of the formed alkene.

161 e carboxyalkanoates can be generated through oxidative cleavage of the gamma-hydroxyalkenals with the

162 ippurate to benzamide and glyoxylate and the oxidative cleavage of the glycyl Calpha-N bond in N-benz

163 eme oxygenase provides further evidence that oxidative cleavage of the heme is the mechanism by which

164 TDO catalyzes oxidative cleavage of the indole ring of L-tryptophan (L

165 tions may be intermediates formed during the oxidative cleavage of the indole ring to give kynurenine

166 henyl-beta,beta'-dioxoporphyrin, followed by oxidative cleavage of the intermediate diol adduct.

167 variety of conditions were examined for the oxidative cleavage of the key cyclopentene intermediate

168 It also performs oxidative cleavage of the model substrate 4-nitrophenyl-

169 This c-type heme oxygenase catalyzes the oxidative cleavage of the model substrate microperoxidas

170 n undergo different transformations, such as oxidative cleavage of the N-PMP-group or N-O bond cleava

171 Oxidative cleavage of the olefin to give an aldehyde fol

172 Oxidative cleavage of the pendant alkene provides access

173 ygenase, and an ABM family monooxygenase for oxidative cleavage of the polyketide moiety.

174 rdoheme product to biliverdin concluded that oxidative cleavage of the porphyrin macrocycle was speci

175 ified recombinant chicken BCO2 catalyzes the oxidative cleavage of the provitamin A carotenoids beta-

176 Oxidative cleavage of the recalcitrant plant polymer lig

177 Oxidative cleavage of the resulting 2-azabicyclo[2.2.1]h

178 s of the acetonide moiety of 41, followed by oxidative cleavage of the resulting diol, gave the aldeh

179 Subsequent oxidative cleavage of the ring originally derived from t

180 are nine-carbon fragments resulting from an oxidative cleavage of the side chain of atROL.

181 Stereospecific oxidative cleavage of the silyl tether in 42 and 43 prov

182 Oxidative cleavage of the styrene derivatives provided a

183 f (E)-3-iodo-2-methylprop-2-enal followed by oxidative cleavage of the terminal vinyl appendage and a

184 ygenase MtmOIV, normally responsible for the oxidative cleavage of the tetracyclic premithramycin B i

185 ive enzymatic hydrolysis using a lipase, and oxidative cleavage of the vicinal diol.

186 koxylation, and hydroxylation) and selective oxidative cleavage of thus synthesized 2-benzylfurans ar

187 amine 2,3-dioxygenase-1 (IDO1; IDO) mediates oxidative cleavage of tryptophan, an amino acid essentia

188 icted to genus Crocus and are synthesized by oxidative cleavage of zeaxanthin followed by glycosylati

189 (Py)Cn(*) acts as a catalyst for the oxidative cleavages of benzil to benzoic and 2,2'-pyridi

190 lic peroxide intermediates and the different oxidative cleavages of II.

191 uilding the diquinane core (AB ring), and an oxidative cleavage/oxidation sequence for annulation of

192 pplied with H(2)O(2), SmLPMO10A catalyzed 18 oxidative cleavages per molecule of ascorbic acid, sugge

193 that DOPA-protein cross-linking and 1,2-diol oxidative cleavage proceed via different mechanisms and

194 ting the formation of oxidation products and oxidative cleavage products of norbixin.

195 safe and practical alternative to mainstream oxidative cleavage protocols, such as ozonolysis and the

196 It was established that flavonol oxidative cleavage reaction and oxidative polymerization

197 In the symmetric oxidative cleavage reaction at C15,C15' position by BCMO

198 c 1,3-propanyl esters designed to undergo an oxidative cleavage reaction catalyzed by a cytochrome P(

199 In polar solvent, the expected Blankespoor oxidative cleavage reaction is the major reaction pathwa

200 CCL-1 uses a selective copper(I)-dependent oxidative cleavage reaction to release d-luciferin for s

201 rmined through application of a CAN-mediated oxidative cleavage reaction.

202 ionones and a central C14-apocarotendial by oxidative cleavage reactions at C9,C10 and C9',C10'.

203 In this manuscript we report that oxidative cleavage reactions can be used to form oxocarb

204 Oxidative cleavage reactions of arylalkenes by tert-buty

205 Features of the oxidative cleavage reactions of diastereomers of dimeric

206 Consecutive oxidative cleavage reactions of these products or the re

207 , but this is not because of photosensitized oxidative cleavage reactions.

208 A sequence of oxidative cleavage/reductive amination/hydrogenolysis en

209 A sequence of oxidative cleavage/reductive amination/reductive cleavag

210 consistent with isotope effects reported for oxidative cleavage/reductive coupling occurring at trans

211 The oxidative cleavage requires the intermediacy of a hemike

212 t, reductive O2 activation induces selective oxidative cleavage, revealing the indestructible charact

213 ry reaction) relative to PO ring-opening and oxidative cleavage (secondary reactions) that solvation

214 through a two-step Hosomi-Sakurai allylation/oxidative cleavage sequence, which is followed by subseq

215 This maize genetic lesion also affects the oxidative cleavage step in ABA synthesis.

216 h 3'-OPO(3) and 3'-OH, and no evidence of 4'-oxidative cleavage termini with either metal.

217 ted waxes in the cuticle undergo spontaneous oxidative cleavage to generate aldehydes and that this p

218 d; this intermediate then undergoes C-H bond oxidative cleavage to give an iridium eta(1)-allyl hydri

219 P), anticipating cytochrome P450 3A-mediated oxidative cleavage to the NMP in hepatocytes.

220 can undergo consecutive reactions including oxidative cleavages to yield a chemically diverse group

221 transformation involving a sigma complex and oxidative cleavage transition state.

222 ure and determined how the change in rate of oxidative cleavage varies from methane to decane.

223 promoted hydrolytic cleavage, but efficient oxidative cleavage was observed in the presence of a mil

224 n some examples such as styrene derivatives, oxidative cleavage was observed instead of epoxidation.

225 A possible mechanism for this unusual oxidative cleavage was proposed on the basis of the stud

226 the corresponding allenyl ether, followed by oxidative cleavage with N-methylmorpholine N-oxide and c