ライフサイエンスコーパス: oxygen extraction fraction

1 first 5 minutes, without changes in cerebral oxygen extraction fraction.

2 d flow, blood volume, oxygen metabolism, and oxygen extraction fraction.

3 lood flow, cerebral blood volume, CMRO2, and oxygen extraction fraction.

4 7% vs. 11+/-15%, p<.05, and increased global oxygen extraction fraction.

5 ue oxygen and significantly reduced regional oxygen extraction fraction.

6 ed as the product of cerebral blood flow and oxygen extraction fraction.

7 tween OxFlow and PET-only measurements of WB oxygen extraction fraction (0.30 0.09 and 0.31 0.09) and

8 erebral blood flow = 40.8-46.3 ml/100 g/min; oxygen extraction fraction = 0.33-0.38).

9 erebral blood flow = 46.2-56.8 ml/100 g/min; oxygen extraction fraction = 0.39-0.50) relative to cont

10 /min, p < .05) and a significant decrease in oxygen extraction fraction (33.4 +/- 5.9 vs. 30.3 +/- 4.

11 [range, 34-88] mumol/100 mL/min) but a lower oxygen extraction fraction (38% [range, 29%-50%] vs 89%

12 n tomography for the measurement of cerebral oxygen extraction fraction and (b) computed tomographic

13 Together, oxygen extraction fraction and cerebral blood flow can p

14 Oxygen extraction fraction and cerebral blood flow were

15 These data suggest that elevated oxygen extraction fraction and disrupted functional conn

16 d flow (p<.001) and resulted in increases in oxygen extraction fraction and ischemic brain volume (17

17 ese 'discordant' voxels differed in baseline oxygen extraction fraction and regulated oxygen demand v

18 measured cerebral blood flow, blood volume, oxygen extraction fraction, and 18F-FDG transport into t

19 (15)O-CO scans were used to derive RV flow, oxygen extraction fraction, and blood volume, respective

20 volume, cerebral oxygen metabolism (CMRO2), oxygen extraction fraction, and brain tissue oximetry we

21 found in seven of 36 patients with increased oxygen extraction fraction, and in two of 39 with normal

22 ned by (15) O-PET cerebral blood flow (CBF), oxygen extraction fraction, and oxygen metabolism was us

23 f regional cerebral blood flow, the regional oxygen extraction fraction, and the regional metabolic r

24 cranial pressure spikes suggesting increased oxygen extraction fraction, and therefore, worsening sup

25 evaluate physiological relationships between oxygen extraction fraction, cerebral blood flow, and cli

26 hout sickle cell trait to assess whole-brain oxygen extraction fraction, cerebral blood flow, degree

27 ion fraction and regulated oxygen demand via oxygen extraction fraction changes, whereas 'concordant'

28 to evaluate whether cerebral blood flow and oxygen extraction fraction could together predict the pr

29 , we studied whether cerebral blood flow and oxygen extraction fraction differed among patients with

30 delivery and utilization using the sd of the oxygen extraction fraction distribution.

31 only in symptomatic patients with increased oxygen extraction fraction (eight of 36 patients; P =.00

32 In summary, oxygen extraction fraction exhibited an 'increase-then-d

33 This study aims to investigate oxygen extraction fraction in cerebral small vessel dise

34 o quickly and non-invasively detect elevated oxygen extraction fraction in individuals with sickle ce

35 traction fraction of 40% (the mean value for oxygen extraction fraction in normal controls) was 14 mm

36 r baseline values of cerebral blood flow and oxygen extraction fraction in the white matter were both

37 We compared baseline cerebral blood flow and oxygen extraction fraction in the whole white matter, no

38 Additionally, the oxygen extraction fraction increased in normal-appearing

39 Further, as white matter oxygen extraction fraction increased, connectivity withi

40 en metabolism (P < 0.001, both comparisons); oxygen extraction fraction increases consistent with isc

41 oxygen delivery associated with reduction in oxygen extraction fraction, independent of Hgb level (p

42 m around layer IV, while the depth-dependent oxygen extraction fraction is increased in layer IV, whe

43 mages were acquired; cerebral blood flow and oxygen extraction fraction maps were obtained from which

44 goal is to determine to what extent elevated oxygen extraction fraction may be uniquely present in pa

45 Non-invasive MRI assessment of oxygen extraction fraction may provide valuable tools fo

46 Longitudinal analyses revealed that adding oxygen extraction fraction measurements to cerebral bloo

47 sonance imaging-based assessment of elevated oxygen extraction fraction might be a viable screening t

48 te the influence of APOE4 on global cerebral oxygen extraction fraction (OEF) and possible mediation

49 ood flow (CBF), cerebral blood volume (CBV), oxygen extraction fraction (OEF) and the cerebral rate f

50 Cerebral blood flow (CBF) and oxygen extraction fraction (OEF) are elevated in SCA, li

51 consumption (MMRO2, mL.min-1 x 100 g-1) and oxygen extraction fraction (OEF) by use of positron emis

52 Patient demographics, comorbidities, oxygen extraction fraction (OEF) data and 24 h interview

53 STLCOS) demonstrated that increased cerebral oxygen extraction fraction (OEF) detected by PET scannin

54 PET measurement of increased oxygen extraction fraction (OEF) identifies patients at

55 t inhalation of (15)O-O(2) provides regional oxygen extraction fraction (OEF) in a shorter acquisitio

56 ase (SCD) on hydroxyurea have lower cerebral oxygen extraction fraction (OEF) than similar patients n

57 volume (CBV), oxygen metabolism (CMRO2) and oxygen extraction fraction (OEF) using 15O PET.

58 Blood flow and oxygen extraction fraction (OEF) were calculated from dy

59 Whole-brain cerebral blood flow (CBF) and oxygen extraction fraction (OEF) were measured by magnet

60 ional resting cerebral blood flow (CBF), (2) oxygen extraction fraction (OEF), and (3) cerebral metab

61 y were used to noninvasively assess regional oxygen extraction fraction (OEF), cerebral blood volume,

62 Oxygen extraction fraction (OEF), defined by the ratio o

63 ng a multiple-variable sensor, and images of oxygen extraction fraction (OEF), derived from positron

64 delivery (DO(2)), oxygen metabolism (MO(2)), oxygen extraction fraction (OEF), or thickness after the

65 cular oxygen tension (PO2) and inner retinal oxygen extraction fraction (OEF), whereas outer retinal

66 bral metabolic stress, reflected by elevated oxygen extraction fraction (OEF), which likely drives st

67 o co-registered PET maps of CBF, CMRO(2) and oxygen extraction fraction (OEF).

68 type indicator [MTI]) and oxygen metabolism (oxygen extraction fraction [OEF] and cerebral metabolic

69 brain tissue oxygen value associated with an oxygen extraction fraction of 40% (the mean value for ox

70 rmal adult human brain in terms of the brain oxygen extraction fraction or OEF.

71 Oxygen extraction fraction (P < 0.0001) but not cerebral

72 ction fraction, and in two of 39 with normal oxygen extraction fraction (P =.08, difference not signi

73 relationship between brain tissue oxygen and oxygen extraction fraction (r = .21, p < .05); the brain

74 a prevents the CMRO(2)-surge by constraining oxygen extraction fraction, reduces mitochondrial oxidat

75 olic rate of oxygen consumption (rMMRO2) and oxygen extraction fraction (rOEF) quantitatively and non

76 issue oxygen than the percentage decrease in oxygen extraction fraction; this suggests that the oxyge

77 Nonetheless, brain tissue may increase oxygen extraction fraction to mitigate hypoxia and delay

78 tive study measuring cerebral blood flow and oxygen extraction fraction using O-PET.

79 Increased white matter oxygen extraction fraction was associated with decreased

80 Notably, the white matter oxygen extraction fraction was elevated in patients with

81 Oxygen extraction fraction was estimated by quantitative

82 dings with hemodynamic impairment (increased oxygen extraction fraction) was investigated.

83 Cerebral blood flow and oxygen extraction fraction were elevated (P < 0.05) in p

84 very, cerebral metabolic rate of oxygen, and oxygen extraction fraction) were measured every 30 minut

85 test metabolic stress, indicated by elevated oxygen extraction fraction, would have the lowest connec