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1 ajor products (i.e., aldehydes and secondary ozonides).
2 y scalable to produce gram quantities of the ozonides.
3 system, as well as the primary and secondary ozonides.
4 s, avoiding the need to isolate or decompose ozonides.
5 oselective reduction of peroxides, including ozonides.
6  with double bonds in lipids to form N-doped ozonides.
7                            For primary amino ozonides, addition of polar functional groups decreased
8                           For tertiary amino ozonides, addition of polar functional groups with H-bon
9                          For secondary amino ozonides, additional functional groups had variable effe
10 pical oxidation products identified included ozonides, aldehydes (hexanal, pentenal, nonanal and none
11 provide direct experimental evidence for the ozonide and establish its propensity for the solution-va
12  findings, showing that water stabilizes the ozonide and lowers the energy of the transition state at
13 large quantities of intramolecular secondary ozonides and alpha-acyloxyhydroperoxy aldehydes were ten
14 mation and unimolecular reactions of primary ozonides and carbonyl oxides arising from the O(3)-initi
15                                              Ozonides and carboxylic acids were generated in certain
16 ol(-1) above the ground state of the primary ozonide, and the decomposition energies range from -5 to
17                       The observed secondary ozonides are consistent with the formation of mainly sec
18                                              Ozonides are known to generate cytotoxic free radicals i
19    It is evident that these tetrasubstituted ozonides are quite stable to triphenylphosphine, borohyd
20                      The resulting 'N-doped' ozonides are safe to handle and lead to the correspondin
21 ivity relationship (SAR) of the antimalarial ozonide artefenomel (OZ439).
22  led to the discovery of a second-generation ozonide, artefenomel (OZ439, 2), which has overcome this
23 ained from the discovery of the antimalarial ozonide arterolane (OZ277), we now describe the structur
24 CTs and the first generation fully synthetic ozonide, arterolane (OZ277, 1), suffer from rapid cleara
25            Here we report the use of primary ozonides as preparative synthetic intermediates for a sa
26                          Acetolysis of these ozonides at low temperature allowed selective cleavage o
27  progressing from quinine and artemisinin to ozonide-based compounds.
28 des collisional stabilization of the primary ozonide by roughly an order of magnitude in pressure.
29 ide, sulfone, and heterocycle-functionalized ozonides by a wide range of post-ozonolysis transformati
30 he discovery of pressure-stabilized divalent ozonide CaO(3) crystal that exhibits intriguing bonding
31        In this paper, we describe the SAR of ozonide carboxylic acid OZ78 (1) as the first part of ou
32 ivity relationship (SAR) of antischistosomal ozonide carboxylic acids OZ418 (2) and OZ165 (3).
33                   These findings unravel the ozonide chemistry at high pressure and offer insights fo
34 er metabolic stabilities than tertiary amino ozonides, consistent with their higher pKa and lower log
35                                              Ozonide decomposition resulted in omega-aldehyde and ome
36                                    Secondary ozonide formation is important even for syn-isomer Crieg
37 evidence for a rate limiting, surface active ozonide formed at the interface.
38  process at low carbon number to a secondary ozonide-forming process at high carbon number.
39 t, ozone-free synthesis of bridged secondary ozonides from 1,5-dicarbonyl compounds and H2 O2 .
40 termed OzMALDI, that simultaneously produces ozonides from all unsaturated lipids.
41                  Primary and secondary amino ozonides had higher metabolic stabilities than tertiary
42 ts imply enhanced production of a persistent ozonide in airway-lining fluids acidified by preexisting
43 ion led to lower concentrations of secondary ozonides, increased concentrations of carbonyls, and sma
44                                  The primary ozonides initially generated upon ozonolysis can be redu
45  involved charge remote fragmentation of the ozonide initiated by homolytic cleavage of the peroxide
46 er interface through the formation of (1) an ozonide intermediate, (2) a hydroperoxide, and (3) cis,c
47 tion pathway for either positive or negative ozonide ion species involved charge remote fragmentation
48 nduced dissociation (CID) of MALDI-generated ozonide ions (with yields in the several ten percent ran
49                        The structure of this ozonide is confirmed by tandem mass spectrometry and its
50 ones reveals that the major tetrasubstituted ozonide isomers possess cis configurations, suggesting a
51                                        These ozonides lose O(2) through thermolysis or photolysis to
52  acid plus a previously unreported ascorbate ozonide (m/z = 223) below pH approximately 5.
53                 The initial products are two ozonide monoadducts, identified as a,b- and c,c-C(70)O(3
54 ore 1,2,4-trioxolane substructure of dispiro ozonides OZ277 and OZ439, we compared the antimalarial a
55 ns suggests that the dissociation of primary ozonide (POZ) of O(3) + ethene and propene can be treate
56                    At the same time, fragile ozonides produced at the sites of unsaturation decompose
57       The unprecedented homolytic opening of ozonides promoted and catalyzed by titanocene(III) is re
58 condensed-phase products including secondary ozonides (SOZ), acids, and aldehydes.
59 ion produces high-molecular-weight secondary ozonides (SOZ), which are known skin irritants, and a mo
60 te up to 79% molar yield of stable secondary ozonides (SOZs) in oxidized triolein and methyl oleate c
61 ied to the phospholipid yielded a mixture of ozonide species with the maximum number of ozone molecul
62 hosphocholine lipids results in formation of ozonides that can be directly analyzed by mass spectrome
63 hyl sulfide gave a mixture of diastereomeric ozonides that proved to be stable for weeks at room temp
64           Epoxide, dicarbonyl, and secondary ozonide THC reaction products were detected from both pu
65                          Cleavage of primary ozonides to form carbonyl oxides occurs with a barrier o
66          The high curative efficacy of these ozonides was most often associated with high and prolong
67         Irrespective of lipophilicity, these ozonide weak acids have relatively low aqueous solubilit
68 haracteristic ozonolysis products, secondary ozonides, were observed on surfaces near the cooking are
69 d preferentially in the intermediate Criegee ozonide, which is commonly formed from olefins.
70                                     Five new ozonides with antimalarial efficacy and ADME profiles su
71                   Primary and tertiary amino ozonides with cycloalkyl and heterocycle substructures w
72                                              Ozonides with para-substituted carboxymethoxy and N-benz
73 eaction enables the selective preparation of ozonides without the use of ozone.