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1 logue YDJ1, suppress the lethality caused by p60v-src.
2 s not essential for, the formation of active p60v-src.
3 ltered as a consequence of transformation by p60v-src.
4 ken embryo fibroblasts (CEFs) transformed by p60v-src.
5 tion of a heterologous Hsp90 target protein, p60(v-src).
6             Since the activation pathway for p60(v-src) and steroid hormone receptors is similar, the
7 -sensitive and produces wild-type amounts of p60v-src at permissive temperatures but becomes p60v-src
8   In Saccharomyces cerevisiae, expression of p60v-src causes cell death, a phenomenon that requires f
9 Cdc37p by incubation at 38 degrees C reduces p60v-src-dependent tyrosine phosphorylation of yeast pro
10            Ydj1 protein was also detected in p60v-src immunoprecipitates from both wild-type and ydj1
11                                 In addition, p60v-src immunoprecipitates from the ydj1-151 strain con
12 t that Cdc37p is required for maintenance of p60v-src in a soluble, biologically active form.
13  the toxicity of the protein tyrosine kinase p60v-src in yeast by reducing its levels or its kinase a
14  mutant produces normal quantities of active p60v-src, indicating that Ydj1p facilitates, but is not
15                                        Also, p60v-src levels are enriched in urea-solubilized extract
16                                     However, p60v-src levels are not low enough to account for the re
17                 In this mutant, the level of p60v-src remains unaltered, but the protein is much less
18                               We also report p60v-src-resistance in a previously identified temperatu
19 v-src at permissive temperatures but becomes p60v-src-resistant at its restrictive temperature, 38 de
20                                          One p60v-src-resistant ydj1 mutant, ydj1-39, which has two p
21 ribe isolation and characterization of novel p60v-src-resistant, temperature-sensitive cdc37 mutants,
22 ibed temperature-sensitive cdc37-1 mutant is p60v-src-sensitive and produces wild-type amounts of p60
23 s, cdc37-34 and cdc37-17, which produce less p60v-src than the parental wild-type strain at 23 degree
24 e been implicated in the formation of active p60v-src tyrosine kinase.
25 dj1p participates in the formation of active p60v-src via molecular chaperone complexes.
26  CDC37 gene is essential for the activity of p60(v-src) when expressed in yeast cells.