ライフサイエンスコーパス: pace

1 tivars at a more inexpensive and accelerated pace.

2 for a battery are emerging at an astonishing pace.

3 gies, many of which are developing at a fast pace.

4 data are being generated at an accelerating pace.

5 evelopment is proceeding at an unprecedented pace.

6 and large human specimens at an accelerated pace.

7 apeutic interventions moves at a much slower pace.

8 novel constructs being developed at a rapid pace.

9 anding of molecular recognition has not kept pace.

10 of occupations continues but has slowed its pace.

11 medical countermeasures at an unprecedented pace.

12 ed health monitoring systems at a tremendous pace.

13 earts was observed when programmed to MPP-AS pacing.

14 g alternative modality for conduction system pacing.

15 AVRT circuits located away from the site of pacing.

16 ce showed increased SAN recovery times after pacing.

17 neurohormonal stimulation, but minimally by pacing.

18 loading induced by high-frequency electrical pacing.

19 iated from the circuit with atrial overdrive pacing.

20 VdP/dtmax were comparable between LVs and HB pacing.

21 ria of healthy dogs followed by rapid atrial pacing.

22 is usually performed by biventricular (BiV) pacing.

23 ejection fraction <=40% during steady-state pacing.

24 left atrium simulated AF induction via rapid pacing.

25 ker-dependent patients received asynchronous pacing.

26 zyme types are necessary for circadian clock pacing.

27 lear-to-cytosolic HDAC4 shift caused by 3-Hz pacing.

28 propagation with responsiveness to drugs and pacing.

29 ronous ventricular activation with RV apical pacing.

30 least as good as during BiV and possibly HB pacing.

31 ization point with biventricular single-site pacing (0.0150+/-0.1725 in LVEDVI(>Median versus) -0.019

32 respectively) and larger than during LVs+RV pacing (11 +/- 9%; p < 0.05).

33 in LVdP/dtmax was similar during LVs and BiV pacing (17 +/- 10% vs. 17 +/- 9%, respectively) and larg

34 ac output by 20 +/- 8% compared to monotonic pacing (-3 +/- 5%; P < 0.05).

35 improvements in the primary outcomes of fast-pace 5- and 10-step stair ascent power.

36 The fast-paced acquisition of genome-based data, however, is far

37 Our study suggests that turning off CRT pacing after LVAD implantation in patients with previous

38 anisms driving these illnesses with the slow pace and high cost of drug development exacerbates this

39 ur results reveal conditions under which the pace and not just the magnitude of external forcing can

40 migrating cells to dynamically regulate the pace and periodicity of the migratory and stationary pha

41 iled instructions on evolving proteins using PACE and phage-assisted non-continuous evolution (PANCE)

42 However, the pace and scale of biotic turnover in response to both th

43 ity over time, relying on concepts about the pace and shape of aging.

44 ight temperatures are increasing at a higher pace and the trend is projected to continue into the fut

45 genomics has the potential to accelerate the pace and utility of genetic screens in Arabidopsis.

46 Rats were unpaced, monotonically paced and RMH paced; the latter had the same average hea

47 127.5) seconds for FFR-guided rate-adaptive pacing and 3.1 (95% CI, -44.1 to 50.3) seconds for conve

48 ures, 188 received biventricular single-site pacing and 43 received MPP-AS.

49 er reviews the current needs for bradycardia pacing and evaluates what standards should be set to dev

50 s measured, variation in clinically measured pacing and high-voltage impedance and impedance trends a

51 ance energy transfer sensors were induced by pacing and minimally by neurohormonal stimulation, provi

52 ewhat artificial condition of a cell without pacing and with no calcium exchange with the extracellul

53 Ice Sheet is losing mass at an accelerating pace, and ice loss will likely continue over the coming

54 data are being generated at an unprecedented pace, and the accurate estimation of gene-level abundanc

55 ormed pre-ablation during sinus rhythm or LA pacing, and electrogram locations were coregistered with

56 ous telemetry, intracardiac electrograms and pacing, and optical mapping studies.

57 social adversity in early life; reproductive pace; and lifetime reproductive success.

58 same average heart rate as the monotonically paced animals.

59 ever, other options, including physiological pacing, are being explored.

60 s strategy is now starting to quickly gather pace as a powerful approach for control of enantioselect

61 genomes are available at an ever-increasing pace, as cultivation and sequencing become cheaper and o

62 nitude of changes in fishing but also on the pace at which changes are imposed.

63 These recent advances show the accelerated pace at which pancreatic ductal adenocarcinoma drugs are

64 tial that typically occurs when the heart is paced at high rates, using a biophysically detailed elec

65 rdiography before and after 2 weeks of daily pacing at a time when pacing was turned off.

66 High-output pacing at the distal His location delivered PHCs.

67 using the Expanded Disability Status Scale, Paced Auditory Serial Addition Test and Symbol Digit Mod

68 Cognitive performance on the Paced Auditory Serial Addition Test with a 3-second inte

69 score) between baseline and R-wave triggered paced beats increases consistently with an increase in t

70 olateral amygdala that is active during self-paced behavioral arrests.

71 nal biventricular pacing with single-site LV pacing, but be mitigated by LV stimulation from 2 widely

72 ccentricity dominated cycles to oscillations paced by a combination of eccentricity, obliquity, and p

73 events within the Upper Kellwasser event is paced by obliquity, under a low-eccentricity orbit.

74 ler advances the state-of-art in respiratory pacing by demonstrating the ability to automatically per

75 nations over the past 640,000 years suggests pacing by Earth's climatic precession, with each glacial

76 R-wave triggered pacing can induce RA, the magnitude of which can be modu

77 tricular (RV) pacing, particularly RV apical pacing, can have deleterious effects on cardiac function

78 approach to the development of local cardiac pacing capabilities in Sub-Saharan African nations.

79 dioverter defibrillator without asynchronous pacing capability.

80 anges in electrogram morphology with loss of pace-capture.

81 L-type calcium current decreases versus 1-Hz-paced cardiomyocytes; these changes were prevented by IP

82 ched off, we propose the novel idea that RMH pacing causes reverse-remodelling.

83 For pacing circuits, we review the complementary roles of im

84 o suturing alone under time pressure or self-paced conditions (P < 0.001).

85 His bundle pacing corrected wide QRS in 54% of all patients with LB

86 Heart failure rats were paced daily for 2 weeks with either respiratory sinus ar

87 ology has been advancing with an astonishing pace, de novo design of complex 3D nanostructures and fu

88 iac implantable electronic devices including pacing devices and left ventricular assist devices.

89 D implantation in patients with previous CRT pacing did not affect mortality, heart transplantation,

90 Suppression of RA by pacing during the absolute refractory period results in

91 Phage-assisted continuous evolution (PACE) enables continuous directed evolution in bacteria

92 Conventional biventricular single-site pacing, even with a quadripolar lead, has reduced effica

93 gy have continued developing at a relentless pace ever since.

94 temporal excitation patterns in periodically-paced excitable media using mathematical models with dif

95 tion, selection and replication) in a single PACE experiment.

96 results provide insight into the assembly of PACE family transporters and their regulation via LTTR p

97 oteobacterial antimicrobial compound efflux (PACE) family.

98 fect of continued CRT versus turning off CRT pacing following continuous flow LVAD implantation.

99 The pacing frequency at which CaT alternans emerged was fast

100 amplitude of AP alternans occurring at high pacing frequency was decreased by I(NaL) inhibition, inc

101 Long-term RV apical pacing has been associated with increased risk of atrial

102 In heart failure, cardiac pacing has little, if any, variation in rate at rest.

103 His bundle pacing (HBP) results in physiological ventricular activa

104 ential HBP followed by left ventricular (LV) pacing (His-Optimized CRT [HOT-CRT]) to maximize electri

105 th left ventricular dysfunction, chronic RMH pacing improved cardiac function through improvements in

106 tions are being produced at an extraordinary pace in developmental and regenerative biology.

107 Marine biota are redistributing at a rapid pace in response to climate change and shifting seascape

108 lates to spring departure date and migration pace in Swainson's Thrush Catharus ustulatus.

109 ts (ICs) have progressed at an unprecedented pace in the past 60 years.

110 al role in carbon removal, yet remains under paced in deployment efforts, mainly because of high cost

111 demonstrate synchronized biventricular (BiV) pacing in a leadless fashion by implementing miniaturize

112 The field of pacing in Africa has evolved in an uncoordinated way acr

113 is a frequency-dependent process, with rapid pacing in canine atrial myocytes inducing oxidative inju

114 from spontaneous activity and under optical pacing in control and drug conditions at multiple doses.

115 effects of LVs with BiV and His bundle (HB) pacing in CRT patients.

116 1, P=0.038) versus biventricular single-site pacing in patients with LVEDVI(>Median).

117 t ventricular ejection fraction <=35% and no pacing indications were included.

118 Pacing-induced AF in 100% of diet-induced obese mice ver

119 P wave and increased susceptibility to burst pacing-induced atrial arrhythmias.

120 illation, hospitalization for heart failure, pacing-induced cardiomyopathy and associated death.

121 ntaneous premature ventricular complexes and pacing-induced ventricular arrhythmias at ZT14, and the

122 eting (DIFAT) technology evaluated the rapid-pacing-induced VTs in each personalized inFAT-based subs

123 elopment activities poorly suited for a fast-paced industrial environment.

124 Respiratory pacing is an alternative approach using electrical stimu

125 Leadless BiV pacing is demonstrated for the first time in both open-c

126 Left bundle branch pacing (LBBP) has recently emerged as a promising altern

127 atrial and right ventricular free wall (DDD) pacing lead to LV dilatation, a thinned septum, and thic

128 isions varied between the fast- and the slow-paced life-history ecotypes.

129 PACE-UP isrctn.com ISRCTN98538934; PACE-Lift isrctn.com ISRCTN42122561.

130 Pacing location was reconstructed from biplane fluorosco

131 The contributions to pace-making of other cell types, including VPAC2-express

132 Sites of entrainment, pace-mapping, and termination during ablation were used

133 These results indicate that LVs pacing may serve as a valuable alternative for CRT.

134 e therapy approach in a canine, rapid atrial pacing model of AF, we demonstrate that NADPH oxidase 2

135 with either respiratory sinus arrhythmia or paced monotonically at a matched heart rate; cardiac fun

136 n regional floras and faunas, or whether the pace of accumulation will decrease due to the depletion

137 Measurements of the pace of aging are needed as surrogate endpoints in trial

138 on measure that is sensitive to variation in pace of biological aging among individuals born the same

139 as a single-time-point measure of a person's pace of biological aging.

140 eryday laboratory routines to increasing the pace of biotechnological production cycles.

141 se as a therapeutic intervention to slow the pace of cellular aging, disease onset, and neuropatholog

142 genic landscape change likely far exceed the pace of change expected from natural geologic processes.

143 nario and alternative scenarios based on the pace of change in educational attainment and contracepti

144 ts over the long times commensurate with the pace of changing climate.

145 s the nuclear transcriptome and controls the pace of chlorophyll degradation in senescing leaves.

146 Given the pace of climate change, it is imperative that we inform

147 that genetic correlations may determine the pace of coevolutionary change, affect species abundances

148 f Pb, which may slow down or even hinder the pace of commercialization.

149 iologists have lagged behind due to the fast pace of computational advancements and tools available t

150 panded the possibilities and accelerated the pace of creating genetically engineered animal models.

151 Given the pace of current change, our management of extant diversi

152 Does malate efflux from the vacuole set the pace of decarboxylation?

153 Three key bottlenecks toward increasing the pace of diffusion and adoption are methodological issues

154 However, the pace of discovery and the ever increasing number of publ

155 have expanded the scope and accelerated the pace of discovery in visual neuroscience.

156 cal research and modeling and accelerate the pace of discovery.

157 However, given the accelerating pace of drug development, there is a crucial need for in

158 t sharing data in a private manner limit the pace of field.

159 The pace of gene discovery has quickened due to advances in

160 The accelerating pace of genome sequencing throughout the tree of life is

161 In recent years, the accelerated pace of genomic data availability has been accompanied b

162 To follow the pace of gold peroxidase (Auperoxidase) nanozyme based bi

163 We propose that the pace of host life history will interact with pathogen li

164 This can account for the slower pace of human development and suggests that differences

165 The pace of knowledge acquisition has been rapid, but ongoin

166 ial, but insufficient for achieving pre-2010 pace of life expectancy growth.

167 We discuss whether pace of life is a determinant, consequence, or adaptive

168 ship represents a slow-fast gradient in the "pace of life" that overrides the expected gleaner-exploi

169 These consequences will affect the pace of mass loss of the Antarctic Ice Sheet.

170 molecular tools have greatly accelerated the pace of mechanistic dissection of membrane contact sites

171 exercise and small molecules that target the pace of metabolic ageing(9-12).

172 While the pace of methodology development in MFA has been rapid, a

173 NK cell depletion reduces the pace of MN degeneration, delays motor impairment and inc

174 ions, while progressing, has not matched the pace of new treatments of human immunodeficiency virus (

175 We show here that GDE3 controls the pace of oligodendrocyte generation by negatively regulat

176 hould have the potential of accelerating the pace of personalized cancer treatment.

177 chnology that has enabled the markedly rapid pace of progress of this field.

178 rsity of clinical trials along with the fast pace of publication makes it difficult to determine the

179 verish ("starving a fever") can increase the pace of recovery, or that showering after sex can preven

180 Since the 2008 global economic crisis, the pace of reduction in poverty and income inequality in th

181 ion is expected to accelerate the timing and pace of reproduction in individuals who experience some

182 al methods may be intractable at the current pace of research.

183 and clinical translation continue to lag the pace of risk variant identification, hindered by the she

184 Given the rapid pace of scientific discovery and clinical data generated

185 ta analysis approaches that keep up with the pace of sequence archives has remained a challenge.

186 ling continue to significantly influence the pace of tele-critical care growth and adoption.

187 SPY, but not SEC, specifically modulates the pace of the Arabidopsis circadian clock.

188 TL4, YWHAB, and YTHDF3), which regulates the pace of the circadian clock.

189 The rapid pace of the coronavirus disease 2019 (COVID-19) pandemic

190 The pace of the COVID-19 pandemic makes it timely to take st

191 The rapid pace of the field demands active efforts to ensure that

192 The pace of the millennial oscillations during the first sta

193 IATED KINASE REGULATOR2 (MAKR2) controls the pace of the root gravitropic response.

194 broadly made autoinducer AI-2 that sets the pace of the V. cholerae QS program.

195 cine for global healthcare, accelerating the pace of transformation of its great potential into tangi

196 by organisms' internal circadian clocks, the pace of which is linked to the solar cycle.

197 that migratory birds and mammals have faster paces of life than their non-migratory relatives.

198 The long-term secular evolution, timing, and pacing of changes in the Early Jurassic carbon cycle tha

199 or RSA - an intrinsic respiratory modulated pacing of heart rate.

200 Natural pacing of the heart results in heart rate variability, a

201 espiratory sinus arrhythmia is physiological pacing of the heart that disappears in cardiovascular di

202 ed to develop a DNA-methylation predictor of Pace-of-Aging, called DunedinPoAm for Dunedin(P)ace(o)f(

203 m a measure of aging-related decline, termed Pace-of-Aging.

204 ) conditions during a badger's first year on pace-of-life explained <10% of variance in the ratio of

205 roduction favoured the evolution of a faster pace-of-life in savannah species that facilitated their

206 history trade-offs as conceptualized in the pace-of-life syndrome (POLS) hypothesis.

207 Life-history and pace-of-life syndrome theory predict that populations ar

208 further insights into the role of His bundle pacing on improving outcomes.

209 The closed-chest pacing only requires the external source power of 0.3 W

210 prominently when the mouse engages in a self-paced operand task.

211 explored how these neurons respond to a self-paced, operant task in freely moving mice.

212 linear features often occurred during slower-paced or stopover movements, perhaps in part to access c

213 rease in stroke volume compared to monotonic pacing (P = 0.03) and improvement in circumferential str

214 Intracardiac electrograms and pacing parameters were recorded.

215 Conventional right ventricular (RV) pacing, particularly RV apical pacing, can have deleteri

216 ean Society of Cardiology guidelines address pacing post-TAVR, they do not provide in-depth discussio

217 ricular fibrillation induction under a rapid pacing protocol (n=7/14 hearts in control versus 1/14 he

218 LVs pacing provides short-term hemodynamic improvement and e

219 creases consistently with an increase in the pacing pulse amplitude, pulse width, and vector spacing.

220 Reductions in pacing rate upon the implementation of AF-induced electr

221 ects of MEF on the electrophysiology at high pacing rates are shown to be proarrhythmic in general.

222 ially deep within the TT network and at high pacing rates.

223 We analyzed the Rush conduction system pacing registry on LBBP to assess the success rates and

224 As compared with baseline, LVs pacing resulted in a larger reduction in QRS area (to 73

225 Left ventricular (LV) epicardial pacing results in slowly propagating paced wavefronts.

226 We propose that respiratory sinus arrhythmia pacing reverse-remodels the heart in heart failure and i

227 d (2) subsequent atrial activation during PV pacing showed that the earliest site was located away fr

228 g the past two decades and at an accelerated pace since 2010.

229 mated using 552 left ventricular endocardial pacing sites pooled together and 25 VT-exit sites identi

230 he reference VT-exit site), and then 5 close pacing sites, resulted in localization error of 7.2+/-4.

231 COVID-19 in humans are emerging at a steady pace, some aspects of the pathogenesis of SARS-CoV-2 can

232 ed with a fundamental innate behaviour, self-paced spatial exploration.

233 enced greater improvements in 5-step regular-pace stair descent time [net difference (95% CI): -0.09

234 ds, and deliver dynamically R-wave triggered pacing stimuli during the absolute refractory period.

235 the development and translation of GTs gain pace, success can only ultimately be realised for patien

236 ution that differs from gradual precessional pacing, suggesting that direct rainfall forcing effects

237 uturing, 2) time-pressured suturing, 3) self-paced suturing plus decision-making, and 4) time-pressur

238 suturing task under four conditions: 1) self-paced suturing, 2) time-pressured suturing, 3) self-pace

239 DLPFC) activations were observed during self-paced suturing, and ventrolateral PFC (VLPFC) deactivati

240 Compared with self-paced suturing, subjective workload (au) was significant

241 As these improvements were made with pacing switched off, we propose the novel idea that RMH

242 ors, and 2 cardiac resynchronization therapy pacing systems.

243 phenotyping combines the excitement of fast-paced technologies, smartphones, cloud computing and mac

244 ilation to metabolic needs; however, current pacing technology requires manual tuning and does not re

245 nables plant growth, albeit at a much slower pace than plants expressing the cognate Se SSU.

246 s have been arriving at a rapidly increasing pace, thanks to decreases in sequencing costs and improv

247 ow the direction of isotherm shifts but at a pace that is much slower than expected, especially in ar

248 indication for an ICD but no indication for pacing, the subcutaneous ICD was noninferior to the tran

249 ts were unpaced, monotonically paced and RMH paced; the latter had the same average heart rate as the

250 To increase resource gain, many herbivores pace their migration with the flush of nutritious plant

251 frequency of ICD shocks or anti-tachycardia pacing therapy.

252 ale population sequencing projects gathering pace, there is a need for strategies that advance diseas

253 on for performing LBBP was a high His-Bundle pacing threshold (n=23) at implant.

254 thcare systems at an unprecedented scale and pace to make their operations 'pandemic proof'.

255 alternative successional pathways and their pace to recovery.

256 P < 0.05) were seen in vitro during variable pacing to mimic RMH.

257 s and 31 +/- 7 ms; both p < 0.05) and LVs+RV pacing (to 108 +/- 37 muVs; p < 0.05; and 29 +/- 8 ms; p

258 we use phage-assisted continuous evolution (PACE) to achieve bioactivity-dependent adaptation of the

259 cy of within 3.5 mm after including up to 11 pacing (training) sites.

260 Temporary LVs pacing (transaortic approach) alone or in combination wi

261 systolic function that persisted beyond the pacing treatment period.

262 osolic Ca(2+) elevation as a result of rapid pacing triggers Ca(2+)-CaM dependent inactivation of RyR

263 y, individuals and pairs performed five self-paced (unsupervised), semi-structured activities around

264 PACE-UP isrctn.com ISRCTN98538934; PACE-Lift isrctn.com

265 Here, we describe respiratory pacing using a closed-loop adaptive controller that can

266 the amplitude, pulse width, and size of the pacing vector.

267 atory sinus arrhythmia compared to monotonic pacing, via improvement in systolic function that persis

268 plant, quadripolar biventricular single-site pacing was activated in all patients (n=506).

269 h LVEDVI(>Median), biventricular single-site pacing was less efficacious compared to patients with LV

270 right ventricular (RV) (LVs+RV), BiV, and HB pacing was performed in 27 patients undergoing CRT impla

271 after 2 weeks of daily pacing at a time when pacing was turned off.

272 cular septum, referred to as LV septal (LVs) pacing, was demonstrated.

273 cardial pacing results in slowly propagating paced wavefronts.

274 indication for an ICD but no indication for pacing were assigned to receive a subcutaneous ICD or tr

275 on of the LA septum or roof during distal CS pacing were the end point for CS-LA connection eliminati

276 ntinuous and continuous evolution (PANCE and PACE), which resulted in ABE8e.

277 HDAC4 expression ratio was decreased by 3-Hz pacing, while nuclear CaMKII phosphorylation was increas

278 ange drivers have allowed GPP uptake to keep pace with anthropogenic emissions.

279 rming hotspot, few species are fully keeping pace with climate.

280 new methods will need to be utilized to keep pace with new discoveries.

281 hile DOAG2 expression gradually increases in pace with pollination-induced ovule development and is l

282 predator plasticity was insufficient to keep pace with prey phenology.

283 vering mechanisms by which host genomes keep pace with rapidly evolving viruses.

284 ese adjustments may be essential for keeping pace with resource phenology, they may prove insufficien

285 o give them the computational skills to keep pace with technological developments.

286 Challenges for this field include keeping pace with technology and data dissemination/harmonizatio

287 larly in the IOL and CL groups and also kept pace with the growth of the fellow eyes.

288 restriction factors as another means to keep pace with the rapid evolution of viruses.

289 icient for phenological events to keep exact pace with their cues-the earlier the year, the more did

290 by explain the actually observed development pace with time; that is all proposed metrics eventually

291 ion of influenza vaccine formulation to keep pace with viral escape from herd immunity.

292 ich climate effects emerge in nature and the pace with which they alter ecosystems.

293 put and stroke volume were increased in rats paced with respiratory sinus arrhythmia compared to mono

294 the earliest LA activation during distal CS pacing with a deca-polar catheter placed with its proxim

295 Among patients who received physiologic pacing with either BiVP or HisBP, the LV end-diastolic a

296 ceiving MPP-AS and biventricular single-site pacing with LVEDVI(<=Median).

297 enlargement using conventional biventricular pacing with single-site LV pacing, but be mitigated by L

298 from 2 widely spaced sites using MultiPoint pacing with wide anatomic separation (MPP-AS: >=30 mm).

299 dult females who walked together at the same pace, with only two adult males and one juvenile accompa

300 tunities for social support, with reports of pacing work to preserve emotional and physical stamina.