ライフサイエンスコーパス: pack against

1 of helical hairpins in which three C helices pack against a central coiled coil.

2 domain III (DIII) and the juxtamembrane stem pack against a central core trimer.

3 At the other end, two Cand1 HEAT repeats pack against a conserved Cul1 surface cleft and bury a C

4 n III (DIII) and the stem region (DIII-stem) pack against a core trimer composed of E1 domains I and

5 n acidic helix joining the chromodomains can pack against a DNA-binding surface of the ATPase motor.

6 contains two antiparallel alpha-helices that pack against a four-stranded beta-sheet.

7 es is helical and uses the analogous face to pack against a groove formed by an N-terminal coiled-coi

8 damentally different from the way the chains pack against a large protein surface.

9 ing barriers as well as nucleosomes actively packed against a barrier.

10 haped form with a glutamine-rich alpha helix packed against a beta-sheet framework.

11 The chromodomain fold - three beta strands packed against a C-terminal alpha helix - mediates prote

12 -Ca(2+)-binding helix-loop-helix (HLH) motif packed against a canonical Ca(2+)-binding EF-hand motif.

13 ree-stranded antiparallel beta-sheet that is packed against a carboxy-terminal alpha helix.

14 r part of its length and is repositioned and packed against a complementary surface groove of conserv

15 so-called "hot dog" fold with a large helix packed against a five-stranded anti-parallel beta-sheet.

16 igonucleotide binding fold, with two helices packed against a five-stranded beta-barrel.

17 positioning, the localization of nucleosomes packed against a fixed barrier, is conjectured to explai

18 d, consisting of a three-stranded beta-sheet packed against a four-stranded beta-sheet.

19 roteins favor RPGs with three local residues packed against a non-local residue.

20 ring a strong driving force for right-handed packing against a neighboring helix.

21 zed both by interactions with the DNA and by packing against a region of the core DBD normally reserv

22 Pro(20) induces a bend in TMH-1, which then packs against a more straightened TMH-2.

23 he amino-terminal caspase recruitment domain packs against a three-layered alpha/beta fold, a short h

24 which three carboxyl-terminal outer helices pack against an inner trimeric coiled coil.

25 core folding with a four-stranded beta-sheet packed against an alpha-helix, seen in the well-studied

26 e antiparallel carboxyl-terminal helices are packed against an amino-terminal trimeric coiled coil.

27 This patch is tightly packed against an underlying sandwich of chloroplast mem

28 25 characterize a hydrophobic cluster, which packs against an irregular beta-sheet, whereas residues

29 Lys213 packs against an otherwise exposed aromatic residue and

30 are exposed to solvent while the first seven pack against and form part of the N-terminal domain, and

31 The N-loop (residues 9-16) is packed against both the sheet and the helix with the two

32 The coiled coil packs against both Fis1 and the second helix of the Mdv1

33 re reveals that the highly conserved Phe-216 packs against conserved Gln-226 residues present on the

34 al helix from Wza, the GfcC C-terminal helix packs against D3.

35 Subsequently, these pairs pack against each other and onto the alpha-helical regio

36 These linear assemblies pack against each other as parallel arrays to form large

37 17 and Leu34 side chains of the same peptide pack against each other at the beta-sheet interface with

38 ), the H-loops of the two catalytic subunits pack against each other at the dimer interface, necessit

39 drophobic heptad repeats and are designed to pack against each other in a "knobs-into-holes" manner.

40 eets (five and four beta-strands each), that pack against each other in a parallel beta-sandwich.

41 ructures, the OB folds of the two components pack against each other through interactions between two

42 nformation wherein the linker and N3 domains pack against each other via a hydrophobic interface.

43 Rpn13's ubiquitin- and Uch37-binding domains pack against each other when it is not incorporated into

44 The two B-box domains pack against each other with the interface formed by res

45 atic changes in the way in which nucleosomes pack against each other within the crystal lattice.

46 folds, in which the second and third repeats pack against each other.

47 -length hexameric forms, these two loops are packed against each other and are stabilized by intimate

48 that the conserved hydrophobic residues are packed against each other in the protein core and that H

49 ntiparallel beta-sheets with 7 main strands, packing against each other, forming a beta-sandwich.

50 twisted and tilted out of the base stack to pack against finger 1 and the tip of finger 2.

51 In the sequestered form, the U37 base packs against G36, and its 2'-hydroxyl group forms a wat

52 we show that in Abeta amyloid fibrils, Met35 packs against Gly33 in the C-terminus of Abeta40 and aga

53 hat the methyl groups of Val80 and Val84 are packed against Gly79 and Gly83, respectively.

54 ce, while the alpha1-alpha2 loop and helix 2 pack against helices 3 and 5 from the opposing monomer.

55 hort fifth helix (helix A') which is closely packed against helix D in an approximately parallel fash

56 Leu56 and Tyr57 of the loop pack against hydrophobic residues from two separate subu

57 ic Tyr describes an all-helix subdomain that packs against interfacial helices, eliminating the four-

58 points away from the beta-barrel instead of packing against it.

59 nd alpha-helix 3, which is partially formed, packs against it.

60 at the subunit interface where helix alpha6 packs against its symmetric partner, helix alpha6'.

61 ARTD15 features an alpha-helical domain that packs against its transferase domain without making dire

62 lated motif in which the alphaCT alpha-helix packs against L1 beta-strands 2 and 3.

63 ethyltransferase (MTase) domain of ZCCHC4 is packed against N-terminal GRF-type and C2H2 zinc finger

64 (6) It is almost a rule that TM helices pack against neighbors in the sequence.

65 by complementarities among side chains that pack against one another at the helix-helix interface.

66 mer in which 2 five-stranded beta-sheets are packed against one another and flanked by alpha-helices

67 the active site loop and supporting loop are packed against one another and stabilized by monomer-mon

68 ntain 4 transmembrane alpha-helices that are packed against one another forming a helical bundle.

69 of five and three antiparallel beta-strands packed against one another.

70 parallel sheet with a two-alpha-helix bundle packed against one face of the sheet.

71 adopts a structure with three alpha-helices packed against one side of a three-stranded antiparallel

72 tiparallel beta-sheet with two alpha-helices packed against one side of this sheet.

73 As in other chemokines, the alpha-helix packs against one face of the beta-sheet.

74 The side chains of Lys331 and Pro417 pack against opposite faces of the guanine nucleotide ba

75 sts of buried residues with side-chains that pack against other CDR residues and apparently act as sc

76 ix (139-143) in the C-terminal domain of PI3 packs against residues 289-295 that form a loop in p. pe

77 the l-fucose endocyclic oxygen and C6 methyl packed against ribose C5 and C4, respectively.

78 nesis screen aimed at determining whether S4 packs against S5 of the pore domain.

79 th three parallel/antiparallel alpha-helices packed against six parallel/antiparallel beta-strands th

80 In our model, Gly residues in GXXXG motifs pack against small Ala or Val side chains to generate th

81 Bulky residues Ile 177 and Ile 181 pack against small residues of the opposite monomer, and

82 re limited to the outer beta-strand F, which packs against strand F' in the tetramer, while the B, C,

83 erminal half of alphaM1 is alpha-helical and packs against structural element(s) that contribute to t

84 n, H2Bub activates the enzymatic assembly by packing against Swd1 and alleviating the inhibitory effe

85 arboxy-terminal beta-hairpin and alpha-helix pack against switch II.

86 n which the alpha-helices of the AP2 domains pack against the beta-sheets of the dimer mates.

87 pectedly, two mobile loops that rearrange to pack against the bound NO in NP4-NO, also rearrange in t

88 he N-terminal substructure of one monomer to pack against the C-terminal substructure of a second mon

89 n-like domain III (DIII) and the stem region pack against the central core of the trimer.

90 surrounded by three C-terminal regions that pack against the coiled coil in an oblique antiparallel

91 ions between the second two helices and also pack against the conserved alanines that interdigitate b

92 sites, respectively, on nucleosomal DNA and pack against the DNA-binding domain on DNA exiting the n

93 nal inhibitory regions have been proposed to pack against the ETS domain and form an autoinhibitory m

94 rd complementarity-determining region (CDR3) pack against the framework and stabilize the global V(H)

95 3 reside near the boundaries of the loop and pack against the framework to form a small hydrophobic c

96 erminus of the first helix and L237 and I241 pack against the helices, perhaps to stabilize alternati

97 The two tryptophan residues were found to pack against the lysine side chain forming an aromatic p

98 The side chains of Ile14 and Ile94, which pack against the nicotinamide and pterin rings of the co

99 e outer ring of transmembrane helices do not pack against the pore-forming helices, creating an appar

100 que combination of hydrophobic residues that pack against the protein core.

101 lt in this structure, and they were found to pack against the putative hinge region implicated in the

102 ophobic environment, but TM7 does not stably pack against the remaining helices.

103 core of the free protein but rotates out to pack against the sugar-phosphate backbone of the DNA in

104 , we propose that in the OT complex Stt3p is packed against the alpha 2-helix of Ost4p by using a "ri

105 with the predominant state comprising the OH packed against the BARAD, contrary to expectations based

106 clusive states: either as part of the CCD or packed against the C-terminal beta-alpha repeated, autop

107 domain, with the opposite end of the channel packed against the domain-swapped subunit.

108 F); N1 of Pex1 is mobile, but the others are packed against the double ring.

109 Also, a hydrophobic Met-16 side chain is packed against the edge of the ring of Tyr-9.

110 ged in a closed configuration with domain II packed against the G domain in the vicinity of the Switc

111 he CYP17A1 active site with the steroid core packed against the I helix and the A ring C3 keto or hyd

112 YS(1252) motif adopts a conformation tightly packed against the kinase C-lobe when Ser-1248 is in the

113 lated nanoparticles are isotachophoretically packed against the migrating depletion front.

114 The latter switches from a helical hairpin packed against the NTD to a five-stranded beta-roll upon

115 Microcolumns of hydrophobic beads packed against the polymethacrylate plugs were utilized

116 n active conformation, with helices 1 and 12 packed against the predicted alpha-helical bundle, in th

117 ion, the unique double PXXP motif is tightly packed against the rest of the protein, rendering this p

118 hat this region is highly mobile and loosely packed against the rest of the protein.

119 y for clathrin binding, is transient and not packed against the rest of the structure.

120 e consists of two antiparallel alpha-helices packed against the same side of a five-stranded beta-she

121 andwich of two nearly parallel alpha helices packed against the same side of a four-stranded beta she

122 ing topology with two parallel alpha-helices packed against the same side of a four-stranded beta-she

123 helical conformation upon complex formation, packing against the 'ABED' sheet of TrkA-d5.

124 s reveal that targeted disruption of helix 1 packing against the ATPase domain accelerates clamp clos

125 a 60 degrees angle above the haem plane and packing against the central I helix with the 3beta-OH in

126 ed binding to GlcNAc may result from Ile-313 packing against the N-acetyl group.

127 per surface of Siah1, with two extended legs packing against the sides of Siah1 by means of a consens

128 to the N-terminus forming an Omega-loop and packing against the structured core of the protein, not

129 tor that present hydrophobic side chains for packing against the surface of haemoglobin.

130 a unique N-terminal extension sequence that packs against the 3-box in a hydrophobic groove centrall

131 We found that one face of the nSH2 domain packs against the 581-593 region of the iSH2 domain.

132 unphosphorylated CheB, the N-terminal domain packs against the active site of the C-terminal domain a

133 Leucine (L) 124 of one subunit packs against the adenine ring of cAMP bound to the oppo

134 A8 packs against the amino-terminal knuckle and forms a hyd

135 to the major groove of the RNA stem and also packs against the amino-terminal zinc knuckle.

136 H2A/H2B dimer, its DNA-binding domain (DBD) packs against the ATPase domain, suggesting an inhibited

137 minal extensions form a small subdomain that packs against the beta-sandwich and mediates dimerizatio

138 unit; presently, the structural element that packs against the buried face of the helix remains unide

139 trimeric hairpin in which domain III (DIII) packs against the central trimer.

140 d within but not between Eph RTK subclasses, packs against the concave beta-sandwich surface near pos

141 rom the surface of insulin, whereas Phe(B24) packs against the core.

142 ch regulates ATP hydrolysis and degradation, packs against the D1 ring of Cdc48 in a coplanar fashion

143 Ftz-F1 domain folds into a novel helix that packs against the DBD but does not contact DNA.

144 ee pentamers, on a conserved loop (G2H) that packs against the dual interpentamer Ca(2+)-binding site

145 lix in the C-terminal inhibitory domain that packs against the ETS domain and perturbs the conformati

146 e tandem N-terminal helical solenoid tightly packs against the FAT and kinase domains.

147 The helix also packs against the GRK1 kinase domain and stabilizes it i

148 esidue 65 did affect the way the polypeptide packs against the methionine-ligated side of the heme.

149 rting a model in which the S4 voltage sensor packs against the pore domain in the hyperpolarized, or

150 the N-terminal tail forms a 3(10) helix that packs against the proximal zinc knuckle and interacts wi

151 ing Ile303, a large hydrophobic residue that packs against the ring meta-C(H) group.

152 the ligand-occupied structure, the 4H domain packs against the SH2 domain and completes its phosphoty

153 The third dimer packs against the side of a face-face interface in a tig

154 Instead, it packs against the TBC domain and forms part of the platf

155 a long C-terminal arm within the ectodomain packs against this coil in an antiparallel manner.

156 The ZipA domain is a six-stranded beta-sheet packed against three alpha-helices and contains the spli

157 sting of a three-stranded beta sheet that is packed against three alpha-helices.

158 3) ORG27569 packs against TMH6, sterically hindering movements of th

159 beta-sheet (residue 25-29, 39-44, and 48-52) packed against two C-terminal antiparallel alpha-helices

160 flat, six-stranded anti-parallel beta sheet packed against two helices.