ライフサイエンスコーパス: palliative

1 therapies for metastatic disease are largely palliative.

2 therapeutic cure, treatments remain largely palliative.

3 DAS is a reasonable initial palliative alternative to BTS in select patients.

4 ersity of Pennsylvania Health System and the Palliative and Advanced Illness Research Center.

5 ntial for curability, which affect patients' palliative and end-of-life care needs.

6 ers, especially if there are receptive local palliative and hospice care champions.

7 ll as quality measures related to integrated palliative and oncology care.

8 eded to develop and test population-specific palliative and supportive care interventions to ensure g

9 cer, aged at least 18 years, admitted to the palliative and supportive care unit at the University of

10 Current treatments are mainly palliative and underscore the unmet clinical need for im

11 previous radiotherapy who otherwise receive palliative androgen deprivation therapy.

12 diotherapy (RT), an established curative and palliative cancer treatment, exerts potent immune modula

13 Specialist palliative care (37% versus 27%, p = 0.002) and AD inclu

14 (SOC) (103), investigational therapy (28) or palliative care (40); 9 died before treatment assignment

15 The Delirium in Palliative Care (DePAC) project was a two-phase sequenti

16 5, p < 0.001), and to not receive specialist palliative care (OR 1.13, 95% CI 1.07-1.19, p < 0.001).

17 e were more likely to not receive specialist palliative care (OR 1.26, 95% CI 1.07-1.49, p = 0.005).

18 Historically, palliative care (PC) services have been underused in thi

19 Palliative care (PC) that has evolved from a focus on en

20 Paediatric palliative care (PPC) endeavours to alleviate the suffer

21 to diagnosis and treatment (five practices), palliative care (two practices), imaging (two practices)

22 e have increased over time despite increased palliative care access.

23 is required to evaluate the cost effects of palliative care across the entire disease trajectory.

24 ve care guidelines, palliative care team and palliative care advice.

25 Pediatric palliative care aims to alleviate suffering and improve

26 odels, telehealth interventions, and primary palliative care also will be discussed.

27 ges to the quality measurement framework for palliative care and a new way to match palliative care s

28 The increased use of specialist palliative care and AD inclusion in hospital files of in

29 In contrast, community-based palliative care and hospice care are more appropriate fo

30 ering as defined by the Lancet Commission on Palliative Care and Pain Relief, by combining WHO mortal

31 ian responses should develop and incorporate palliative care and symptom relief strategies that addre

32 is very limited evidence about the need for palliative care and symptom relief to guide the implemen

33 s when making decisions on whether to select palliative care and transition to hospice or whether to

34 fessional role, education level, training in palliative care and years working in direct care.

35 Postgraduate diplomas in palliative care are available in Kenya, South Africa, Ug

36 and opportunities for earlier integration of palliative care are being explored.

37 logy organizations' recommendations of early palliative care as a cancer care best practice for patie

38 heir use, are self-management of ascites and palliative care at home.

39 The available evidence suggests that palliative care be widely adopted by clinicians in all o

40 Palliative care began in academic centers with specialty

41 The benefits of palliative care can only be realized through effective d

42 strated more complex dynamics, but expanding palliative care capacity to meet clinical guidelines and

43 sultation, protocol for family meetings, and palliative care clinicians embedded in ICU rounds).

44 lies, whether done by oncology clinicians or palliative care clinicians, requires patient-centered co

45 respond to information about prognosis from palliative care clinicians.

46 ility of any of one hospital-based resource (palliative care consultants) or four ICU-based resources

47 (median, 3 vs 2 d; p = 0.001), less frequent palliative care consultation (17.6% vs 32.4%; p = 0.0006

48 Intervention arm patients received a palliative care consultation from an interprofessional t

49 s and communication, propose indications for palliative care consultation in paediatric advanced hear

50 To investigate the use of palliative care consultation in patients with ESKD in th

51 Our study suggests that routine palliative care consultation may positively impact the c

52 The median time from palliative care consultation to death was 10 hours (inte

53 Early triggered palliative care consultation was associated with greater

54 Most (n = 225; 75%) reported that palliative care consultation was underutilized.

55 e-sustaining therapy, triggers for automated palliative care consultation, protocol for family meetin

56 ummarise attitudes and perceived barriers to palliative care consultation.

57 Palliative care consultations may be underused at the en

58 Palliative care education and guidelines for palliative care could improve the self-efficacy of care

59 Study findings show that although palliative care decreases symptom burden, it is still un

60 these principles of care, with more primary palliative care delivered by oncology clinicians.

61 care, overcoming disparities, and innovating palliative care delivery and reimbursement.

62 ch of the five clinical models of specialist palliative care delivery, including outpatient clinics,

63 ver, there is still minimal to no identified palliative care development in most African countries.

64 Palliative care education and guidelines for palliative

65 r-resourced rural practices; and using novel palliative care education delivery methods to increase c

66 The evidence for palliative care exists predominantly for patients with c

67 The odds of receiving palliative care for both white and minority stroke patie

68 s are critical components of providing early palliative care for everyone everywhere.

69 ease during the study period in provision of palliative care for inpatients with ESKD, significant ra

70 und studies to clearly elucidate the role of palliative care for patients and families living with th

71 ncludes education, screening, treatment, and palliative care for refugees and nationals and prioritis

72 dations related to treatment, follow-up, and palliative care from the 2018 version of this guideline.

73 s included facility type and availability of palliative care guidelines, palliative care team and pal

74 Palliative care has evolved over the past five decades a

75 Early research studies on the economics of palliative care have reported a general pattern of cost

76 t palliative care services and 19 specialist palliative care health professionals (predominantly comm

77 Palliative care improves quality of life in patients wit

78 ients (11%), treatment was redirected toward palliative care in 14 patients (13%), and surveillance f

79 ation can introduce patients and families to palliative care in a nonthreatening way, build patient t

80 e team for more complex cases-is unique from palliative care in adults given its focus on care of the

81 In a secondary analysis of the PAL-HF trial (Palliative Care in Heart Failure), we analyzed differenc

82 While the evidence base for palliative care in HF is promising, it is still in its i

83 Palliative care in high-risk patients targeted by an Ear

84 ceives the same priority as other aspects of palliative care in oncology.

85 ge and achieve health equity with respect to palliative care in patient groups that have been underst

86 plant recipients, and emphasizes the role of palliative care in patients with cardiorenal syndrome.

87 Much of the available data on palliative care in racial and ethnic minorities and peop

88 e the illness-related suffering and need for palliative care in Rohingya refugees and caregivers in B

89 tifies some of the challenges of integrating palliative care in rural and remote cancer care.

90 We also discuss the role of palliative care in supporting a holistic approach to sym

91 advance the field and improve integration of palliative care in the care of children with heart disea

92 Limitations to understanding disparities in palliative care include the fact that much of the availa

93 robust evidence demonstrates that specialty palliative care integrated into oncology care improves p

94 ific, cultural, and system-based barriers to palliative care integration and optimal end-of-life care

95 Early palliative care integration for cancer patients is now t

96 mptom-related causes, attitudes toward early palliative care integration, and patient-parent concorda

97 Among those who received the palliative care intervention (33 women and 42 men), wome

98 15, to usual care (UC) (n = 75) or UC plus a palliative care intervention (UC + PAL) (n = 75) at a si

99 and assessed for differential effects of the palliative care intervention by sex.

100 rs investigated whether an interdisciplinary palliative care intervention in addition to evidence-bas

101 An interdisciplinary palliative care intervention in advanced HF patients sho

102 there may be a sex disparity in response to palliative care intervention, suggesting that sex-specif

103 search is needed to define the standards for palliative care interventions and to refine the models t

104 studies show that advance care planning and palliative care interventions are associated with a redu

105 In this context, advance care planning and palliative care interventions designed to clarify patien

106 In addition, trials of home-based palliative care interventions have shown promise for imp

107 th heart failure derive similar benefit from palliative care interventions remains unknown.

108 provement of depression resulting from early palliative care interventions; results for quality of li

109 Efforts are needed to adapt and integrate palliative care into community practice.

110 Immediate global action to integrate palliative care into health systems is an ethical and ec

111 procedures to guide integration of specialty palliative care into oncology have led to a proliferatio

112 idence regarding the need for integration of palliative care into routine oncology care and describes

113 clinical opinion (PCO) on the integration of palliative care into standard oncology care for all pati

114 Integration of palliative care into the routine care of children, adole

115 en and parents expressed opposition to early palliative care involvement (2 [1.6%] and 8 [6.2%]) or p

116 ents and their families may not need or want palliative care involvement early in the disease traject

117 Despite recognition that palliative care is an essential component of any humanit

118 An important part of palliative care is discussing preferences at end of life

119 ng a deeper understanding of the barriers to palliative care is necessary from patients, families, re

120 Palliative care is part of Parkinson disease management.

121 Although information on palliative care is unevenly distributed, the available i

122 , suggesting that sex-specific approaches to palliative care may be needed to improve outcomes.

123 could identify patients wishing to focus on palliative care measures.

124 utilizing clinical ethics consultation, and palliative care medicine clinicians.

125 erefore, little is known about whether early palliative care models are applicable in these low-resou

126 rs and mediators of the effect of integrated palliative care models on patient-reported outcomes and

127 Hence, adapting palliative care models, using culturally appropriate nov

128 Efficient patient-centred models of palliative care must be validated, taking into account r

129 These findings likely signal unmet palliative care needs among seriously ill patients with

130 Patients with glioma present with complex palliative care needs throughout their disease trajector

131 tic expectations about return home and unmet palliative care needs, suggesting the need for integrati

132 Palliative care nurses and physicians can be trained to

133 ealth professionals (predominantly community palliative care nurses).

134 ICU admissions for "palliative care of a dying patient" and "potential organ

135 tions, and provide a practical framework for palliative care of caregivers in oncology settings.

136 The effect of palliative care on important end-of-life outcomes in pat

137 vidence supporting the beneficial effects of palliative care on patient coping as well as the mechani

138 ents in coping mediated the effects of early palliative care on patient-reported outcomes.

139 perts-a nephrologist and a general internist-palliative care physician-reflect on the care of a patie

140 urgical, mechanical circulatory support, and palliative care practices; advocates for the development

141 eys that assessed attitudes about specialist palliative care presence and integration into the ICU se

142 ng, as well as acceptability of 23 published palliative care prompts (triggers) for specialist consul

143 ric palliative oncology-encompassing primary palliative care provided by the multidisciplinary oncolo

144 linary oncology team as well as subspecialty palliative care provided by the palliative care team for

145 nterprofessional team led by board-certified palliative care providers within 48 hours of ICU admissi

146 patients with advanced cancer be referred to palliative care providers.

147 The palliative care referral rate increased significantly, f

148 rtise to account for limited local specialty palliative care resources.

149 tional Assessment of Chronic Illness Therapy-Palliative Care scale (115.7 versus 120.3; P=0.27) score

150 tional Assessment of Chronic Illness Therapy-Palliative Care scale (FACIT-Pal), assessed at 6 months.

151 tional Assessment of Chronic Illness Therapy-Palliative Care scale (range, 0 [worst] to 184 [best]; m

152 tional Assessment of Chronic Illness Therapy-Palliative Care score mean difference, 4.7 [95% CI, -6.3

153 Each of these five models of specialist palliative care serve a different patient population alo

154 y less likely than white patients to receive palliative care services (adjusted odds ratio [aOR], 0.7

155 under the care of community-based specialist palliative care services and 19 specialist palliative ca

156 ite these substantial unmet needs, specialty palliative care services are infrequently consulted for

157 isparities is necessary to improve access to palliative care services for the vulnerable ESKD populat

158 formation showed an increased development of palliative care services in a subset of African countrie

159 Little is known about disparity in use of palliative care services in such patients in the inpatie

160 k for palliative care and a new way to match palliative care services to patients with advanced cance

161 lyses from RCTs in the 2012 PCO on providing palliative care services to patients with cancer and/or

162 creening, pathology, oncology, surgical, and palliative care services, although some examples of inno

163 revention, improving cancer surveillance and palliative care services, and developing targeted treatm

164 ent, disease management, rehabilitation, and palliative care services, coordinated across the differe

165 it presents many challenges in oncologic and palliative care settings.

166 th increasing numbers of deaths from cancer, palliative care should be available to relieve suffering

167 Because ASCO guidelines state that palliative care should be provided concurrently with oth

168 Here, 2 oncologists, 1 of whom is also a palliative care specialist, debate the guideline and dis

169 patients, family and friend caregivers, and palliative care specialists to update the 2012 American

170 ion; differences arise from diverse roles of palliative care specialists within cancer care globally.

171 using the CriSTAL tool to stimulate earlier Palliative Care Team (PCT) referral served as an underly

172 availability of palliative care guidelines, palliative care team and palliative care advice.

173 l competency training for all members of the palliative care team and referring providers needs to be

174 subspecialty palliative care provided by the palliative care team for more complex cases-is unique fr

175 pports that timely involvement of specialist palliative care teams can enhance the care delivered by

176 ng the growing demand for the involvement of palliative care teams in the management of the dying pat

177 Referral of patients to interdisciplinary palliative care teams is optimal, and services may compl

178 The demand for palliative care to be integrated throughout the cancer t

179 , acceptability, and efficacy of integrating palliative care to improve the quality of life and care

180 therapy, orthopaedic surgery and specialist palliative care to minimize the impact of metastatic bon

181 The delivery of palliative care to patients with advanced cancer and the

182 ng in this population, highlight the role of palliative care to promote effective coping strategies i

183 patient preferences for communication about palliative care topics, best practices for communication

184 .22 [1.53-3.21] and 3.11 [2.05-4.71]; formal palliative care training (1.71 [1.32-2.21]); working in

185 and Northern Ireland (four hospices and one palliative care unit).

186 hrombosis in patients admitted to specialist palliative care units (SPCUs).

187 clinics, inpatient consultation teams, acute palliative care units, community-based palliative care,

188 including those receiving care in specialist palliative care units.

189 exity may benefit from an admission to acute palliative care units.

190 f serious health-related suffering requiring palliative care until 2060 by world regions, age groups,

191 r contributor to explain race disparities in palliative care use after stroke.

192 We compared palliative care use among minority groups (black, Hispan

193 e the association between race/ethnicity and palliative care use within and between the different hos

194 08, p < 0.001), and not receiving specialist palliative care was more likely (OR 1.03, 95% CI 1.02-1.

195 Palliative care was not significantly associated with di

196 d working in a facility where guidelines for palliative care were available (1.39 [1.03-1.88]).

197 from surgery, anesthesia, critical care, and palliative care were notified of the patient's frailty a

198 eeds, suggesting the need for integration of palliative care within the long-term acute care hospital

199 e cancer trajectory, combined with a limited palliative care workforce, means that new models of care

200 rstanding of decision-making concepts (e.g., palliative care) is impaired; 5) treatment limitations a

201 cology services (eg, paediatric oncology and palliative care), improving access to opioids, and devel

202 ent developed vomiting and diarrhea, started palliative care, and died 60 hours after the fall.

203 acute palliative care units, community-based palliative care, and hospice care.

204 rapy, radiotherapy, treatment of recurrence, palliative care, and quality of survivorship.

205 f patients with primarily noncancer illness, palliative care, compared with usual care, was statistic

206 Palliative care, compared with usual care, was statistic

207 spital bills for them), stillbirths averted, palliative care, contraception, and child physical and i

208 prioritization of both active treatments and palliative care, despite limited evidence that cancer is

209 are many delirium evidence-practice gaps in palliative care, including that the condition is under-r

210 Accumulating data demonstrate that early palliative care, integrated with oncology care, not only

211 ightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London.

212 ampled from four specialties (critical care, palliative care, oncology, and surgery).

213 arities, enhancing education and research in palliative care, overcoming disparities, and innovating

214 g group representing critical care medicine, palliative care, pediatric medicine, nursing, social wor

215 was based on a series of trials showing that palliative care, when added to standard oncology treatme

216 he best possible care to patients, including palliative care.

217 tom relief and other essential components of palliative care.

218 ost often associated with symptoms requiring palliative care.

219 hrough 2014, of which 76,659 (1.5%) involved palliative care.

220 mpt treatment of early invasive cancers, and palliative care.

221 insurance) were also less likely to receive palliative care.

222 the key point of entry for timely access to palliative care.

223 l barriers to optimal health care, including palliative care.

224 models to further improve access to quality palliative care.

225 been routinely incorporated into oncology or palliative care.

226 st practices recognized for dissemination of palliative care.

227 ons and supplies can provide pain relief and palliative care; however, the practical availability of

228 erated adaptive biased coin design to either palliative chemoradiotherapy or radiotherapy alone for t

229 INTERPRETATION: Palliative chemoradiotherapy showed a modest, but not st

230 th nonresectable colorectal cancer receiving palliative chemotherapy has a 5-year overall survival of

231 local ablative therapies for metastases, and palliative chemotherapy, targeted therapy, and immunothe

232 stic parameter when deciding for adjuvant or palliative chemotherapy.

233 minated disease and the majority are offered palliative chemotherapy.

234 how health-care providers view success in a palliative condition.

235 urpose To evaluate the efficacy, safety, and palliative durability of collimated-beam CT-guided percu

236 The short-term palliative efficacy was assessed through comparison of v

237 d health professional, layperson, and family palliative expertise to account for limited local specia

238 atients who received >= 10 mg prednisone for palliative indications compared with patients who receiv

239 of patients who receive corticosteroids for palliative indications.

240 mplex disease which is normally treated with palliative intent and systemic therapy.

241 The 42 NSCLC patients treated with palliative intent at Maria Sklodowska-Curie National Res

242 find the best one for patients treated with palliative intent.

243 sponse duration, and toxicity of single dose palliative liver radiotherapy (RT) for symptomatic HCC p

244 mprovement of index symptoms after receiving palliative liver RT with median response duration of 3 m

245 uding the integrated provision of active and palliative management strategies.

246 nterventions to slow disease progression and palliative measures to improve quality of life should bo

247 l oncology, psychiatry, nursing, hospice and palliative medicine, communication skills, health dispar

248 and developing regional training capacity in palliative medicine.

249 rgency departments among older patients with palliative needs has led to the development of several s

250 g, caregiver support, in-home personal care, palliative nursing, and social work) and specific plan c

251 nts in the specific domains within pediatric palliative oncology care including family-centered commu

252 The field of pediatric palliative oncology-encompassing primary palliative care

253 he composite endpoint in subjects undergoing palliative operations (OR: 0.38; 95% CI: 0.15 to 0.99; p

254 astatic breast cancer patients is limited to palliative options and represents an unmet clinical need

255 The symptom subscale of the Integrated Palliative Outcome Scale for LTNCs (IPOS Neuro-S24) comp

256 Pain palliative outcomes and opioid use after FICS were compa

257 Clinical management of ACM is largely palliative, owing to an absence of therapies that target

258 In this multicenter comparison of palliative PDA stent and BT shunt for infants with ducta

259 omplete versus staged surgery (i.e., initial palliative procedure for possible later complete repair)

260 s, however, a benefit in patients undergoing palliative procedures and a significant interaction betw

261 t of 27 preliminary indicators that measured palliative processes of care across the surgical episode

262 patients with cancer, both for curative and palliative purposes.

263 tive score system for 30-day mortality after palliative radiotherapy by using predictors from routine

264 ith metastatic cancer receiving first course palliative radiotherapy from 1 July, 2007 to 31 December

265 weeks before trial entry, with exception of palliative radiotherapy.

266 icine, making most therapeutic interventions palliative rather than curative.

267 teroids were administered for cancer-related palliative reasons or cancer-unrelated indications.

268 urgical treatment that provides an effective palliative result and durable prevention for impending p

269 iewed unresectable HCC patients treated with palliative RT in our institution.

270 by sex and use in adjuvant or neoadjuvant vs palliative setting.

271 ration of platinum-doublet chemotherapy in a palliative setting.

272 uvant/adjuvant and 560 of 1,016 (55.1%) in a palliative setting.

273 CT (41%); 11, radiotherapy only (6%); and 4, palliative single agent therapies (2%).

274 C-PVTT patients receiving no intervention or palliative Sorafenib alone (1-y OS of 0%) or Sorafenib w

275 ly assigned patients (1:2) to receive either palliative standard of care treatments alone (control gr

276 v 4-5) and randomized in a 1:2 ratio between palliative standard-of-care (SOC) treatments (arm 1) and

277 g, symptom assessment, and issues related to palliative surgery.

278 art disease, who may have undergone previous palliative surgical procedures, may be unsuitable for ve

279 al cancer (mCRC) patients during consecutive palliative systemic regimens.

280 In mCRC patients during palliative systemic treatment, SMI losses, irrespective

281 g the pathogenesis of AD, the development of palliative therapies is still lacking.

282 Oncologists may use this to tailor palliative therapy for patients.

283 to 2 who were planned to receive first-line palliative therapy.

284 dysfunction of secretory epithelia with only palliative therapy.

285 pice models, policies that promote combining palliative transfusions with hospice services are likely

286 Both received palliative treatment consisting of fully covered self-ex

287 ucocorticoid treatment represents a standard palliative treatment for Duchenne muscular dystrophy (DM

288 ged 65 years and older deemed fit enough for palliative treatment had more toxicities or a worse outc

289 red SEMS is an effective and safe method for palliative treatment of MBO.

290 s, within admissible limits of toxicity, for palliative treatment of metastatic NSCLC.

291 rpose To evaluate the safety and efficacy of palliative treatment of patients with pathologic pelvic

292 % were deceased, and 11.7% were on active or palliative treatment.

293 st frequent tumor site: genitourinary (45%); palliative treatment: n = 41 (34%)].

294 onchoscopic lung volume reduction (bLVR) are palliative treatments aimed at reducing hyperinflation i

295 r, we reviewed the evidence on commonly used palliative treatments and their effect on quality of lif

296 cause of worldwide mortality for which only palliative treatments are available for patients with la

297 ordance about prognosis, misconceptions that palliative treatments are curative, and disputes about p

298 ) is a chronic autoimmune disease, with only palliative treatments available.

299 sticum is currently incurable, although some palliative treatments exist.

300 better understand the benefits and burden of palliative treatments for patients with recurrent head a