ライフサイエンスコーパス: pancreatic cyst

1 onic pancreatitis; and 125 with noncancerous pancreatic cysts).

2 h pancreatic cysts, 158 (55.8%) had only one pancreatic cyst.

3 ghty-three (19.6%) patients had at least one pancreatic cyst.

4 l adjunct in the assessment of patients with pancreatic cyst.

5 oblastomas, pheochromocytomas, and renal and pancreatic cysts.

6 group including patients with other types of pancreatic cysts.

7 l is effective for the treatment of mucinous pancreatic cysts.

8 lind trial of 39 patients with mucinous-type pancreatic cysts.

9 s emerged as an adjunct to the assessment of pancreatic cysts.

10 lance after 5 years for patients with stable pancreatic cysts.

11 differentiating between benign and malignant pancreatic cysts.

12 the evaluation of diagnostically challenging pancreatic cysts.

13 % and a positive predictive value of 75% for pancreatic cysts.

14 dy from the pool without reported incidental pancreatic cysts.

15 ing in differentiating malignant from benign pancreatic cysts.

16 graphy is the preferred imaging modality for pancreatic cysts.

17 treatment and strategies for surveillance of pancreatic cysts.

18 number of patients are being diagnosed with pancreatic cysts.

19 ential clinical utility in the evaluation of pancreatic cysts.

20 reased identification of small, asymptomatic pancreatic cysts.

21 gy records were reviewed for the presence of pancreatic cysts.

22 dy, of them 158 patients were diagnosed with pancreatic cysts, 117 patients (74%) diagnosed with IPMN

23 Of 283 patients with pancreatic cysts, 158 (55.8%) had only one pancreatic cy

24 percentages of male and female patients with pancreatic cysts (20.4% vs 18.8%) were not significantly

25 cancer 4), 23 serous cystadenomas, 13 other pancreatic cysts, 27 pancreatic endocrine tumors, 16 chr

26 y than control subjects to have at least one pancreatic cyst (40 of 110 patients [36%] vs 25 of 110 c

27 More than 2% of adults harbor a pancreatic cyst, a subset of which progresses to invasiv

28 hol is not required for effective EUS-guided pancreatic cyst ablation, and when alcohol is removed fr

29 ne whether alcohol is required for effective pancreatic cyst ablation, if removing alcohol from the a

30 between collected variables and presence of pancreatic cysts among patients with ADPKD.

31 nitial computed tomography (CT) revealing no pancreatic cyst and subsequent follow-up MR imaging depi

32 and pancreatic cancer, in the evaluation of pancreatic cysts and choledocholithiasis, and in perform

33 eflect the pathophysiological development of pancreatic cysts and diabetes.

34 the diversity of genomic alterations seen in pancreatic cysts and their clinical significance.

35 ntral nervous system, renal cell carcinomas, pancreatic cysts and tumors, pheochromocytomas, endolymp

36 se-positive CT (4 chronic pancreatitis and 1 pancreatic cyst) and 18 false-negative CT (all with true

37 ,039 CT or MR scans, 290 patients (1.2%) had pancreatic cysts, and 168 of these patients (0.7%) had n

38 ledocholithiasis, extrinsic compression from pancreatic cysts, and cholangitis), and 3 with bile leak

39 tory of pancreatitis, patients with mucinous pancreatic cysts, and elderly patients with new-onset di

40 s, abnormal left-right axis, hepatorenal and pancreatic cysts, and embryonic lethality.

41 pathology, current management guidelines for pancreatic cysts, and integration of DNA-based molecular

42 of acute pancreatitis, chronic pancreatitis, pancreatic cysts, and pancreatic cancer in the general p

43 Pancreatic cysts are a clinical quandary in both diagnos

44 Hepatic and pancreatic cysts are also common.

45 It is critical that all pancreatic cysts are appropriately characterized, as tre

46 Because pancreatic cysts are becoming more frequently diagnosed,

47 Pancreatic cysts are best evaluated by a team of healthc

48 noma and high-grade dysplasia among mucinous pancreatic cysts are clinically needed.

49 rotein Bicaudal-C (Bicc1) provokes renal and pancreatic cysts as well as ectopic Wnt/beta-catenin sig

50 ter smaller than 10 mm-is similar to that of pancreatic cysts at autopsy and higher than that of panc

51 The prevalence of pancreatic cysts at single-shot fast SE MR imaging-espec

52 tic cysts at autopsy and higher than that of pancreatic cysts at transabdominal ultrasonography.

53 70 years old or older are now diagnosed with pancreatic cysts, but it is not clear which ones require

54 y-guided fine needle aspiration (EUS-FNA) of pancreatic cysts, but there is conflicting evidence for

55 that subjects with CEL-MODY develop multiple pancreatic cysts by the time they develop diabetes and t

56 of MR imaging examination were evaluated for pancreatic cysts by using axial and coronal single-shot

57 sis of pancreatic cancer, the detection of a pancreatic cyst can be a source of anxiety for both the

58 Management of pancreatic cysts can be guided using novel Markov-based

59 with elevated HbA1c were more likely to have pancreatic cysts compared to individuals with lower HbA1

60 osine monophosphate-activated kinase (AMPK), pancreatic cyst development was independent of AMPK sign

61 enocarcinoma remotely at the location of the pancreatic cyst diagnosed 11 months prior.

62 Incremental improvements in pancreatic cyst diagnosis have occurred with new biomark

63 patients with asymptomatic small incidental pancreatic cysts (diameter, 5-20 mm) with two or more ma

64 , increase of MPD diameter, absence of extra pancreatic cysts, elevated serum CA19-9 levels, and elev

65 The natural history and management of pancreatic cysts, especially for branch duct intraductal

66 zed trial of patients undergoing EUS-FNA for pancreatic cyst evaluation, we found the risk of infecti

67 Samples of pancreatic cyst fluid (n = 5, collected before surgery)

68 and intrahepatic CCAs, as well as in matched pancreatic cyst fluid and bile duct brushings.

69 c and biliary IOPNs, as well as in PDACs and pancreatic cyst fluid and bile duct cells from the same

70 pid species were performed on peri-operative pancreatic cyst fluid and pre-operative plasma from IPMN

71 The cellular content of pancreatic cyst fluid aspirate is often suboptimal for a

72 agnostic utility of amphiregulin (AREG) as a pancreatic cyst fluid biomarker to differentiate non-muc

73 trospective study to evaluate AREG levels in pancreatic cyst fluid by ELISA from 33 patients with a h

74 pic ultrasound-guided fine-needle aspiration pancreatic cyst fluid from 31 institutions.

75 nalysis of DNA mutations and proteins within pancreatic cyst fluid have identified potential biomarke

76 Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful adjunct in the assessm

77 NG, AND PARTICIPANTS: For this cohort study, pancreatic cyst fluid specimens from 31 medical centers

78 ade associated proteins are also detected in pancreatic cyst fluids, which allows us to link proteins

79 tic tumor tissues as well as in premalignant pancreatic cyst fluids.

80 The PPV of small pancreatic cysts for prediction of benignity was 87% (75

81 Incidental pancreatic cysts found by using CT or MR imaging are ass

82 , and 41 patients (26%) diagnosed with other pancreatic cysts (group B).

83 rasound findings, ancillary studies, current pancreatic cyst guidelines, follow-up, and expanded test

84 In comparison, other modalities and current pancreatic cyst guidelines, such as the American Gastroe

85 Incidental pancreatic cysts had a hazard ratio of 3.0 (95% CI confi

86 Sixteen (5.7%) patients with pancreatic cysts had malignant pancreatic tumors, and 75

87 uencing and targeted sequencing of the major pancreatic cysts has identified unique mutational profil

88 ternational guidelines for the management of pancreatic cysts have been developed over the past decad

89 he diagnosis and management of patients with pancreatic cysts have progressed significantly in recent

90 difficult to detect malignancy in neoplastic pancreatic cysts; however, a detailed cyst fluid analysi

91 multi-institutional cohort of patients with pancreatic cyst in real time.

92 agnetic resonance (MR) imaging prevalence of pancreatic cysts in a cohort of patients with autosomal

93 HbA1c) is associated with the development of pancreatic cysts in a pancreatic surveillance program.

94 s of experience) who were trained to measure pancreatic cysts in a similar manner.

95 We identified multiple pancreatic cysts in all eight diabetic mutation carriers

96 enhances renal cystogenesis without inducing pancreatic cysts in Pkd1(V/V) mice.

97 As pancreatic cyst incidence rises, likely due to the ubiqu

98 f asymptomatic HRIs frequently detects small pancreatic cysts, including curable, noninvasive high-gr

99 The prevalence of pancreatic cysts increased with age (r = 0.96).

100 eneralized fat necrosis, due to rupture of a pancreatic cyst into the portal vein, occurred in a 57-y

101 Accurate diagnosis of the nature of pancreatic cysts is challenging but more important than

102 Although the overall rate of malignant pancreatic cysts is low, it remains higher than the gene

103 d to 1 of 2 groups that underwent EUS-guided pancreatic cyst lavage with either 80% ethanol (control)

104 Pancreatic cysts may be intraductal mucinous neoplasms,

105 these patients is complex, and knowledge of pancreatic cyst natural history and predictors of neopla

106 nts whose CT or MR imaging showed incidental pancreatic cysts; no-cyst cohort was three-to-one freque

107 Our primary outcome was the presence of pancreatic cysts on initial surveillance in patients wit

108 ignificantly associated with the presence of pancreatic cysts (P = .0004) and with liver volume (P =

109 y of patients, asymptomatic small incidental pancreatic cysts remained stable during a median follow-

110 Diagnosis of pancreatic cysts remains challenging due to limitations

111 The management of pancreatic cysts requires risk stratification for malign

112 ciprofloxacin vs placebo in patients with a pancreatic cyst requiring EUS-FNA at multiple centers in

113 hibit extrahepatic manifestations, including pancreatic cysts, splenomegaly, and common bile duct dil

114 herefore, we recommend surgical excision for pancreatic cysts that are increasing under observation,

115 tal papillary mucinous neoplasms (IPMNs) are pancreatic cysts that can give rise to pancreatic cancer

116 of a computerized search, 510 patients with pancreatic cysts that had been detected at computed tomo

117 ural history, and predictors of neoplasia in pancreatic cysts to determine which patients can safely

118 not only sensitive and specific for various pancreatic cyst types and advanced neoplasia arising fro

119 uated the yield of continued surveillance of pancreatic cysts up to and after 5 years of follow up.

120 elationship between mortality and incidental pancreatic cysts varied by age: hazard ratios were 1.40

121 aintained registry of patients evaluated for pancreatic cysts was queried (1995-2016).

122 Patients with ADPKD and a pancreatic cyst were 5.9 times more likely to have a PKD

123 and January 2005 for the ICD-9 diagnosis of pancreatic cyst were reviewed.

124 The majority (n = 75) of small pancreatic cysts were benign.

125 Thirty-one consecutive patients with pancreatic cysts were enrolled in the study.

126 Pancreatic cysts were evaluated in 539 patients.

127 2:58) with 370 asymptomatic small incidental pancreatic cysts were included.

128 In a univariate analysis, pancreatic cysts were more prevalent in patients with AD

129 Conclusion Pancreatic cysts were more prevalent in patients with AD

130 ine phosphatase levels, and absence of extra pancreatic cysts were predictors of invasiveness.

131 , three on chronic pancreatitis, and none on pancreatic cysts) were identified, with a total study po

132 The images were reviewed for presence of pancreatic cysts, which were classified as simple and no