ライフサイエンスコーパス: parabrachial

1 lateral thalamic nucleus, which received no parabrachial afferent inputs.

2 ss nociceptive signals (laminae I, V) and in parabrachial and hypothalamic neurons positioned to supp

3 ing partially segregated distribution in the parabrachial and paranigral subdivisions of the ventral

4 ojections from HSD2 neurons, namely, lateral parabrachial and prelocus coeruleus nuclei.

5 Recordings from identified spino-parabrachial and spino-periaqueductal gray neurons indic

6 ntine and laterodorsal tegmental, cuneiform, parabrachial, and deep cerebellar.

7 injected into the right thalamus or lateral parabrachial area (LPb) in mice.

8 eriaqueductal gray matter (PAG), and lateral parabrachial area (LPb), and many cells project to more

9 s, periaqueductal grey matter (PAG), lateral parabrachial area (LPb), caudal ventrolateral medulla an

10 al stimulation of afferents from the pontine parabrachial area (part of the spino-parabrachio-amygdal

11 c-Fos expression in the dorsal horn and the parabrachial area of the brainstem.

12 In the parabrachial area, activated neurons were localized in t

13 Our results imply that in the parabrachial area, there is predictable overlap between

14 in the Kolliker-Fuse nucleus of the lateral parabrachial area.

15 perficial laminae of the dorsal horn and the parabrachial area.

16 neural pathways intersect and overlap in the parabrachial area.

17 rojections inhibited nociceptive activity in parabrachial bitter taste neurons.

18 These observations suggest that the parabrachial brainstem region is the primary source of n

19 escent labels to demonstrate that individual parabrachial cells project to both structures.

20 Parabrachial CGRP neurons receive diverse threat-related

21 persistent pain states, and that the lateral parabrachial complex (PB) conveys relevant nociceptive i

22 their efferent target nuclei in the pontine parabrachial complex (PB) in rats during sodium deprivat

23 f the RVM.SIGNIFICANCE STATEMENT The lateral parabrachial complex (PB) relays nociceptive information

24 N) and PVH(MC4R) neurons both project to the parabrachial complex (PB), they synaptically engage dist

25 locus ceruleus, CGRP(+) processes within the parabrachial complex, and lack projections to caudal ven

26 i: the nucleus tractus solitarii and pontine parabrachial complex, and periventricular areas includin

27 n (VRC) subdivisions, A5 noradrenergic area, parabrachial complex, and spinal cord.

28 lateral habenula nucleus, substantia nigra, parabrachial complex, cerebellum, spinal trigeminal trac

29 dorsal raphe, locus coeruleus, median raphe, parabrachial complex, pontine oralis, pedunculopontine a

30 leus, and internal lateral subnucleus of the parabrachial complex.

31 Here we found that parabrachial gustatory neurons can receive afferent proj

32 , expression enrichment of the adult lateral parabrachial is also found with genes from independent g

33 via a brainstem pontine relay located in the parabrachial/Kolliker-Fuse nuclear complex.

34 al nucleus/nucleus of the solitary tract; 6) parabrachial/Kolliker-Fuse nuclei; and 7) periaqueductal

35 eam (RLS) that generates some neurons of the parabrachial, lateral lemniscal, and deep cerebellar nuc

36 ucleus of the solitary tract in the medulla, parabrachial, locus coeruleus, pontine and caudal dorsal

37 related to suppressed inhibition to lateral parabrachial (LPB) neurons from the CeA in animals of ei

38 in the nucleus of the solitary tract and the parabrachial, medial vestibular, prepositus, and suprage

39 approaches in the rat, we found that lateral parabrachial neurons are pivotal in this pathway by glut

40 Optical inhibition of the terminals of parabrachial neurons in the BF impairs cortical arousals

41 irect primary afferent input to mature spino-parabrachial neurons was enhanced following neonatal tis

42 at regulate arousal (locus ceruleus, CGRP(+) parabrachial neurons).

43 y innervated and released synaptic GABA onto parabrachial neurons, which in turn projected to and rel

44 ding arousal system, including the brainstem parabrachial neurons, which promote arousal in response

45 nt synapses onto immature rat lamina I spino-parabrachial neurons, which serve as a major source of n

46 tinal fat on gustatory coding in the pontine parabrachial nuclei (PBN) by recording from single neuro

47 itary tract (NST) not only send axons to the parabrachial nuclei (PbN), but also receive descending p

48 n the parastrial, tuberal, dorsal raphe, and parabrachial nuclei and in the retrorubral area, ventrol

49 Secondary analyses examined the parabrachial nuclei and other brain regions involved in

50 We found that within the parabrachial nuclei and the immediately adjacent tegment

51 palatability and gustatory responses in the parabrachial nuclei are reduced by systemic morphine.

52 , and the tractus solitarius nuclei, lateral parabrachial nuclei in the hindbrain.

53 axic center" in the Kolliker-Fuse and medial parabrachial nuclei of dorsolateral pons (dl-pons) plays

54 te putamen and cerebral cortex, and from the parabrachial nuclei to the central extended amygdala, la

55 al region and also CGRP projections from the parabrachial nuclei to the olfactory-anterior septal reg

56 is, amygdala, periaqueductal gray, raphe and parabrachial nuclei) and in regions involved in learning

57 re localized in the Kolliker-Fuse and medial parabrachial nuclei, but some were also found in lateral

58 BS, including the locus ceruleus complex and parabrachial nuclei, may interfere with descending corti

59 enotypes were found in the Kolliker-Fuse and parabrachial nuclei, periaqueductal gray, pedunculoponti

60 ea, the superior and inferior colliculi, the parabrachial nuclei, the locus coeruleus, subcoeruleus a

61 c fasciculus, and ansa peduncularis from the parabrachial nuclei.

62 icerulear region, rostroventral medulla, and parabrachial nuclei.

63 dunculopontine tegmental, Kolliker-Fuse, and parabrachial nuclei.

64 indirect routes through the superior lateral parabrachial nuclei.

65 lateral hypothalamic, Edinger-Westphal, and parabrachial nuclei.

66 ubstantia nigra, central gray; raphe nuclei; parabrachial nuclei; locus ceruleus, nucleus of the soli

67 e-locus coeruleus (pLC), and central lateral parabrachial nucleus (cLPBN), respectively.

68 ornical organ (SFO) and the external lateral parabrachial nucleus (elPB).

69 tral nucleus of the amygdala (lateral part), parabrachial nucleus (external lateral subnucleus), area

70 us of the solitary tract (rNTS), the lateral parabrachial nucleus (LPB), and the central amygdala (Ce

71 rolateral periaqueductal gray (PAG), lateral parabrachial nucleus (LPB), caudal pressor area, and lam

72 at neurons in the dorsal part of the lateral parabrachial nucleus (LPBd) glutamatergically transmit c

73 or (Htr2c)-expressing neurons in the lateral parabrachial nucleus (LPBN(Htr2c) neurons) inhibit sodiu

74 solitarius (NTS) projections to the lateral parabrachial nucleus (lPBN) and calcitonin-gene related

75 NMDA) glutamatergic receptors in the lateral parabrachial nucleus (LPBN) are involved in the control

76 y was to investigate the role of the lateral parabrachial nucleus (LPBN) in mediating dorsal PAG modu

77 The lateral parabrachial nucleus (lPBN) is a major target of spinal

78 re designed to determine whether the lateral parabrachial nucleus (lPBN) mediates acquisition of cond

79 Although lateral parabrachial nucleus (lPBN) neurons are implicated in th

80 tion to be mediated by a PVH(MC4R)-->lateral parabrachial nucleus (LPBN) pathway.

81 We also report that neurons in the lateral parabrachial nucleus (LPBN), a brain area that is also i

82 ight the dorsal vagal complex (DVC), lateral parabrachial nucleus (lPBN), and central nucleus of the

83 ventromedial hypothalamus (VMH) and lateral parabrachial nucleus (LPBN).

84 al ventrolateral medulla (RVLM), and lateral parabrachial nucleus (lPBN); however, EB significantly a

85 ar dendritic zone, which included the medial parabrachial nucleus (mPB).

86 end towards suppression of activation in the parabrachial nucleus (P = 0.0683).

87 The parabrachial nucleus (PB) is a complex structure located

88 The parabrachial nucleus (PB) is a major relay of noxious an

89 The parabrachial nucleus (PB) is known to mediate key respir

90 ract (NTS), ventrolateral medulla (VLM), and parabrachial nucleus (PB) remained.

91 the periaqueductal gray matter (PAG) to the parabrachial nucleus (PB) were studied in the rat follow

92 ea (LHA), the periaqueductal gray (PAG), the parabrachial nucleus (Pb), and the nucleus of the solita

93 the nucleus submedius of the thalamus (Sm), parabrachial nucleus (PB), lateral hypothalamus (LH), or

94 othalamic nuclei, lateral hypothalamic area, parabrachial nucleus (PB), nucleus of the solitary tract

95 ratory chemosensory pathways converge on the parabrachial nucleus (PB), which sends glutamatergic pro

96 to the nucleus tractus solitarius (NTS) and parabrachial nucleus (PB).

97 lutamatergic neurons in the external lateral parabrachial nucleus (PBel) containing calcitonin gene r

98 lutamatergic neurons in the external lateral parabrachial nucleus (PBel) play a critical role in arou

99 d the inner division of the external lateral parabrachial nucleus (PBel).

100 Interestingly, the lateral parabrachial nucleus (PBL), a critical node in the affec

101 hypothalamus (PVN), and the pontine lateral parabrachial nucleus (PBL; an important component of asc

102 Rs specifically reduce excitatory drive from parabrachial nucleus (PBN) afferents onto CRF neurons.

103 tergic input to the BNST originates from the parabrachial nucleus (PBN) and consists of asymmetric ax

104 rain areas have been shown to project to the parabrachial nucleus (PBN) and exert inhibitory and exci

105 rvation is due to aberrant activation of the parabrachial nucleus (PBN) and it could be prevented by

106 rior vestibular nucleus (IVN) project to the parabrachial nucleus (PBN) and Kolliker-Fuse (KF) nucleu

107 The pontine parabrachial nucleus (PBN) and medullary reticular forma

108 two major extranuclear targets of rNST, the parabrachial nucleus (PBN) and medullary reticular forma

109 ve (CT) afferents, those connecting with the parabrachial nucleus (PBN) and reticular formation (RF),

110 Previous studies showed that the parabrachial nucleus (PBN) contains neurons that are nec

111 eviously reported that lesions of the medial parabrachial nucleus (PBN) enhanced d-fenfluramine (DFEN

112 Rats with ibotenic acid lesions of the parabrachial nucleus (PBN) failed to learn a taste avers

113 The parabrachial nucleus (PBN) has long been recognized as a

114 e "waist" area and external subnuclei of the parabrachial nucleus (PBN) have been implicated in the p

115 es for cannabinoid mechanisms of the pontine parabrachial nucleus (PBN) in modulating intake of presu

116 receives ascending gustatory inputs from the parabrachial nucleus (PbN) in the brainstem and sends pr

117 esions of the gustatory (medial) zone of the parabrachial nucleus (PBN) in the pons eliminate the sal

118 nucleus of the solitary tract (rNST) to the parabrachial nucleus (PBN) in the pons.

119 The parabrachial nucleus (PBN) is an area of the brain stem

120 The parabrachial nucleus (PBN) is located in the rostral dor

121 ctivity (FLI) in several subdivisions of the parabrachial nucleus (PBN) known to be responsive to gus

122 LepRb neurons, which project to and activate parabrachial nucleus (PBN) neurons that control SNS acti

123 aining most of the cells that project to the parabrachial nucleus (PBN) of the pons.

124 Retrograde labeling studies in mice from the parabrachial nucleus (PBN) show that less than 20% of su

125 ted peptide (CGRP)-expressing neurons in the parabrachial nucleus (PBN) suppress feeding.

126 Hypoglycemia activates neurons of the parabrachial nucleus (PBN) that coexpress leptin recepto

127 the nucleus of solitary tract (NST) and the parabrachial nucleus (PBN) that modulate taste-elicited

128 n gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) that transmit anorexic signal

129 ns in the gustatory and visceral zone of the parabrachial nucleus (PBN) to gamma-aminobutyric acid (G

130 evaluated the contributions of the hindbrain parabrachial nucleus (PBN) to systemic Ex4-induced hypop

131 ions, direct delivery of bretazenil into the parabrachial nucleus (PBN), a direct target of AgRP neur

132 mpathetic afferents activates neurons in the parabrachial nucleus (PBN), a region known to play a rol

133 bed nucleus of the stria terminalis (vBNST), parabrachial nucleus (PBN), and nucleus of the solitary

134 as seen not only in the iNTS but also in the parabrachial nucleus (PBN), and the central nucleus of t

135 oral somatosensory and taste activity in the parabrachial nucleus (PbN), implicated for roles in gust

136 area postrema (AP), vestibular nucleus (VN), parabrachial nucleus (PBN), nucleus ambiguus (NA), dorsa

137 The two major components of the pontine parabrachial nucleus (PBN), the medial (gustatory) and l

138 aused by hyperactivity of neurons within the parabrachial nucleus (PBN).

139 tions from taste responsive sites within the parabrachial nucleus (PBN).

140 diate feeding behaviour, such as the lateral parabrachial nucleus (PBN).

141 d Fos-li in the external lateral division of parabrachial nucleus (PBNel) in intact but not in CD rat

142 ral and external lateral subdivisions of the parabrachial nucleus (slPB and elPB, respectively), the

143 tial input from glutamatergic neurons in the parabrachial nucleus and adjacent precoeruleus area.

144 whereas CCK-induced neural activation in the parabrachial nucleus and amygdala appeared normal.

145 , ventrolateral periaqueductal gray, lateral parabrachial nucleus and caudal nucleus of the solitary

146 al organ and increased Fos-ir in the lateral parabrachial nucleus and caudal ventrolateral medulla.

147 e activation of neurons localized within the parabrachial nucleus and central amygdala, which constit

148 ways associated with affective pain, such as parabrachial nucleus and medial thalamic nucleus, as wel

149 cal arousal, whereas the projection from the parabrachial nucleus and precoeruleus region, relayed by

150 nnervation of BNST originates in the pontine parabrachial nucleus and targets its anterolateral secto

151 , the A5 area, the ventrolateral part of the parabrachial nucleus and the Kolliker-Fuse nucleus were

152 ke-immunoreactive fibers was detected in the parabrachial nucleus and the NTS, with notable staining

153 s, and reduced spinofugal innervation of the parabrachial nucleus and the periaqueductal gray, import

154 al tegmental nucleus, nucleus pontis oralis, parabrachial nucleus and the white matter in between the

155 ent projections-to the lateral hypothalamus, parabrachial nucleus and ventral tegmental area-each imp

156 alcitonin gene-related peptide (CGRP) in the parabrachial nucleus are critical for relaying pain sign

157 trate that parallel outputs from the lateral parabrachial nucleus arise from specific cell types with

158 somatic afferents to the VRG via the lateral parabrachial nucleus causes resetting of respiratory rhy

159 eas many NPS-positive neurons in the lateral parabrachial nucleus coexpress corticotropin-releasing f

160 Reversible blockade of the lateral parabrachial nucleus eliminated entrainment.

161 ed with regard to the forebrain influence on parabrachial nucleus function during CTA acquisition.

162 lated polypeptide alpha (calca), a marker of parabrachial nucleus in mammals.

163 in mice by providing GABAergic input to the parabrachial nucleus in the brainstem.

164 nd dorsal raphe nucleus in the midbrain; and parabrachial nucleus in the pons.

165 Hyperactivity of the parabrachial nucleus is also thought to cause starvation

166 ion of projections from these neurons to the parabrachial nucleus is reinforcing, and increases ethan

167 The parabrachial nucleus is thought to mediate the suppressi

168 hin-expressing neurons in the arcuate or the parabrachial nucleus lowered T(b).

169 somatic afferents, (2) establish whether the parabrachial nucleus mediates entrainment, (3) examine r

170 that include monoaminergic pathways and the parabrachial nucleus network.

171 expressing) VMN targets of glucose-elevating parabrachial nucleus neurons.

172 oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice (Oxtr(PBN) neurons) are key

173 1) opioid receptor subtype is present in the parabrachial nucleus of the pons and that these receptor

174 signals from the spinal cord to the lateral parabrachial nucleus of the pons.

175 No double labeled perikarya were seen in the parabrachial nucleus or in the amygdaloid nuclei.

176 Destruction of the lateral parabrachial nucleus produced a 44 % inhibition of pepto

177 e data suggest that this central amygdala to parabrachial nucleus projection influences the expressio

178 ereas the projection of these neurons to the parabrachial nucleus promotes consumption of ethanol as

179 ic neurons of the lateral septum and lateral parabrachial nucleus regulate pancreatic secretion.

180 amate into the lateral septum or the lateral parabrachial nucleus stimulated vagal pancreatic efferen

181 Here we show that, in mice, neurons in the parabrachial nucleus that express the prodynorphin gene

182 he outer external lateral subdivision of the parabrachial nucleus that project to the laterocapsular

183 However, the identities of neurons in the parabrachial nucleus that regulate feeding are unknown,

184 Glutamatergic projections from the parabrachial nucleus to the central amygdala are implica

185 emonstrate that this neural circuit from the parabrachial nucleus to the central nucleus of the amygd

186 Further, cholinergic input from the lateral parabrachial nucleus to the hypothalamus plays a major r

187 The projections from the parabrachial nucleus to the midline and intralaminar tha

188 Finally, the waist area of the parabrachial nucleus was densely labeled after CTb injec

189 eptum and external subnucleus of the lateral parabrachial nucleus which contained more CRF-ir neurons

190 ral nucleus of the solitary tract and medial parabrachial nucleus), neuroendocrine system (periventri

191 tral amygdala neurotensin neurons was to the parabrachial nucleus, a brain region known to be importa

192 o play a role in appetite suppression is the parabrachial nucleus, a heterogeneous population of neur

193 us (mPVN), 4.1-times in the external lateral parabrachial nucleus, and 2.6-times in both the inferior

194 eriaqueductal gray, locus coeruleus, lateral parabrachial nucleus, and commissural nucleus tractus so

195 ventral tegmental area, periaqueductal gray, parabrachial nucleus, and dorsal vagal complex.

196 mentum, medial vestibular nuclei and lateral parabrachial nucleus, and in brainstem regions associate

197 regions including the infralimbic cortex and parabrachial nucleus, and limbic regions including the l

198 ventral tegmental area, periaqueductal gray, parabrachial nucleus, and locus coeruleus.

199 mic area, ventrolateral periaqueductal gray, parabrachial nucleus, and nucleus of the solitary tract)

200 s, dorsomedial hypothalamic nucleus, lateral parabrachial nucleus, and nucleus of the solitary tract.

201 in pons, midbrain (mesencephalic tegmentum, parabrachial nucleus, and periaqueductal gray), hypothal

202 y sensation, receives primary input from the parabrachial nucleus, and projects to the insular cortex

203 ates the activity of pain-related neurons in parabrachial nucleus, and that, in chronic pain, this in

204 emammillary nucleus, ventral tegmental area, parabrachial nucleus, and the dorsal vagal complex.

205 rey, the dorsal and linear raphe nuclei, the parabrachial nucleus, and the dorsal vagal complex.

206 lamic nucleus, lateral hypothalamus, lateral parabrachial nucleus, dorsal raphe nucleus, and nucleus

207 retroambiguus, but not those innervating the parabrachial nucleus, elicited USVs in both male and fem

208 dial hypothalamus, lateral hypothalamus, and parabrachial nucleus, identifying these brain regions as

209 lei, locus coeruleus, raphe complex, lateral parabrachial nucleus, inferior olivary complex, vestibul

210 th aversion learning (the lateral and medial parabrachial nucleus, intermediate and caudal nucleus tr

211 nuclei, but some were also found in lateral parabrachial nucleus, intertrigeminal nucleus, principal

212 detected in: paratrigeminal nucleus, lateral parabrachial nucleus, Kolliker-Fuse nucleus, ventrolater

213 nuclei, nucleus of the posterior commissure, parabrachial nucleus, laterodorsal and pedunculopontine

214 , periaqueductal gray, raphe nuclei, lateral parabrachial nucleus, locus coeruleus, spinal trigeminal

215 rvate autonomic control sites, including the parabrachial nucleus, nucleus of solitary tract, and ven

216 f the amygdala, periaqueductal gray, lateral parabrachial nucleus, nucleus of the solitary tract, dor

217 gray, dorsal raphe, ventral tegmental area, parabrachial nucleus, nucleus tractus solitarius, rostra

218 lar cortex, but not in basolateral amygdala, parabrachial nucleus, or nucleus of the solitary tract.

219 ca, hippocampus, nucleus tractus solitarius, parabrachial nucleus, paraventricular nucleus of the hyp

220 in brainstem regions, including the lateral parabrachial nucleus, periaqeductal gray, and ventrolate

221 and pontine reticular formation, cerebellum, parabrachial nucleus, periaqueductal gray, thalamus, hyp

222 d double-labeled neurons originated from the parabrachial nucleus, pericoeruleus area, and caudal reg

223 d in brainstem regions including the lateral parabrachial nucleus, peripeduncular area and ventrolate

224 ), ventrolateral periaqueductal gray, dorsal parabrachial nucleus, periventricular and rhomboid nucle

225 r, dorsal and central superior raphe nuclei, parabrachial nucleus, pre-locus coeruleus region, NTS, a

226 dings of significant c-Fos expression in the parabrachial nucleus, the central nucleus of the amygdal

227 thalamic neurons, the subiculum, the lateral parabrachial nucleus, the cuneate/gracilis nuclei, and t

228 ar hypothalamic nuclei, the external lateral parabrachial nucleus, the locus coeruleus, and the nucle

229 ervous system regions, including the lateral parabrachial nucleus, the periaqueductal gray, and lamin

230 cold-induced c-Fos expression in the lateral parabrachial nucleus, thus indicating a site of action w

231 tphal nucleus, locus coeruleus (LC), lateral parabrachial nucleus, ventrolateral medulla (VLM) and do

232 for parallel processing was reflected in the parabrachial nucleus, where sweetened milk intake result

233 are synaptically connected to neurons in the parabrachial nucleus, which relays visceral information

234 er-Fuse, intertrigeminal region, and lateral parabrachial nucleus.

235 ect to the nucleus of the solitary tract and parabrachial nucleus.

236 stria terminalis,medial amygdala, and medial parabrachial nucleus.

237 d subparafascicular nucleus, and the lateral parabrachial nucleus.

238 sensory trigeminal nucleus, and the lateral parabrachial nucleus.

239 targets the viscerosensory subregions of the parabrachial nucleus.

240 us nucleus and reversed the asymmetry in the parabrachial nucleus.

241 ad axons that projected to the contralateral parabrachial nucleus.

242 tract (NTS) and with SP, CGRP and MOR in the parabrachial nucleus.

243 the innermost region of the external lateral parabrachial nucleus.

244 antial projection may be relayed through the parabrachial nucleus.

245 teral medulla, A5 area, and internal lateral parabrachial nucleus.

246 ay matter, dorsal raphe nucleus, and lateral parabrachial nucleus.

247 ssing neurons in the CeA that project to the parabrachial nucleus.

248 y VR1-positive fibers project to the lateral parabrachial nucleus.

249 re expressed at higher levels in the lateral parabrachial nucleus.

250 dbrain raphe nuclei, periaqueductal gray and parabrachial nucleus.

251 dalar nucleus, retrorubral area, and lateral parabrachial nucleus.

252 pothalamus, periaqueductal gray, and lateral parabrachial nucleus.

253 cleus of the solitary tract, and the lateral parabrachial nucleus.

254 ration provide an input to the region of the parabrachial nucleus.

255 nical feeding regions of arcuate nucleus and parabrachial nucleus.

256 n structures such as the locus coeruleus and parabrachial nucleus.

257 ne (PZ)-project to the wake-promoting medial parabrachial nucleus; (2) PZ neurons express c-Fos after

258 also are necessary for hypothalamic but not parabrachial or amygdala responses to gastric sensory st

259 omponent that is reciprocal to the vestibulo-parabrachial pathway and a non-reciprocal component to r

260 We propose that this amygdalo-parabrachial pathway is a key regulator of both chronic

261 ing partially segregated distribution in the parabrachial (PB) and paranigral (PN) ventral tegmental

262 e basolateral amygdala (BLA) and the pontine parabrachial (PB) area in brain slices from control (unt

263 n especially critical role for the brainstem parabrachial (PB) complex in regulating electrocortical

264 The parabrachial (PB) complex mediates both ascending nocice

265 Cells in the paraventricular (PVN) and parabrachial (PBN) nuclei and brainstem showed dual proj

266 rogold-labeled cells, neurons in the lateral parabrachial, periaqueductal gray, and dorsal raphe cont

267 ted nuclei have mostly TH neurons, and their parabrachial pigmented nuclei have dual VGluT2-TH neuron

268 uT2 neurons lacking TH; their paranigral and parabrachial pigmented nuclei have mostly TH neurons, an

269 outputs is >50%, and mainly targets the A10 parabrachial pigmented nucleus (PBP) and A8 (retrorubal

270 tamate neurons within three sub-regions: the parabrachial pigmented nucleus (PBP), parainterfascicula

271 erentiation and survival of a rostrolateral (parabrachial pigmented nucleus and dorsomedial substanti

272 ndopaminergic neurons in the dorsal VTA, the parabrachial pigmented nucleus, the substantia nigra par

273 within three anatomically distinct regions (parabrachial pigmented, paranigral, and caudal linear nu

274 Cell-specific lesions of the parabrachial-precoeruleus complex produced behavioral un

275 A cholinergic projection from the parabrachial region (PBR) of the brainstem to the visual

276 diffuse labeling was present in the lateral parabrachial region and the lateral rim of the caudal sp

277 esults suggest that cholinergic cells of the parabrachial region may coordinate the relay of visuosen

278 ulation is a cholinergic projection from the parabrachial region of the brainstem (PBR).

279 The parabrachial region of the brainstem reticular formation

280 C-Fos expression in the dorsal horn and parabrachial region was never observed on brushing the s

281 on, the medial and lateral pontine gray, the parabrachial region, and the accessory inferior olive.

282 to the ventrobasal thalamic complex (VB) and parabrachial region, the two major spinal ascending site

283 ons, but no cells were labeled in the NTS or parabrachial region.

284 dorsal and median raphe, lateral and medial parabrachial, solitary, ventrolateral periaqueductal gra

285 The medial and ventral lateral parabrachial subnuclei projected to the oval paracentral

286 ograde cell body labeling pattern within the parabrachial subnuclei was then analyzed.

287 ateral, dorsal lateral, and external lateral parabrachial subnuclei.

288 or agonist) we show that the central lateral parabrachial subnucleus (PBcl) provides Dyn inputs to th

289 beta subunit (CTb) into the external lateral parabrachial subnucleus (PBel) produced both retrograde

290 intense staining was in the external lateral parabrachial subnucleus (PBel), including dendrites exte

291 The external lateral parabrachial subnucleus projected to the lateral parafas

292 ived an input only from the internal lateral parabrachial subnucleus.

293 l, but also in the adjacent lateral crescent parabrachial subnucleus.

294 r PBN (LPBNi) and by 90.5+/-4% in the medial parabrachial subregion (MPBN).

295 ared to left side in the locus coeruleus and parabrachial, superior vestibular, and supragenualis nuc

296 cortical and other forebrain sites via this parabrachial-thalamic pathway.

297 robably secreted from neurons in the lateral parabrachial, the periaqueductal gray, and/or the dorsal

298 h TH- and non-TH-containing dendrites in the parabrachial VTA, a region that contains mainly prefront

299 the increased synaptic GluR1 labeling in the parabrachial VTA, but also increased the number of GluR1

300 l localization of the 5-HT1A receptor in the parabrachial (VTApb) and paranigral (VTApn) subdivisions