ライフサイエンスコーパス: paradoxical

1 m that also promotes sRNA generation remains paradoxical.

2 BMI) and mortality is complex and frequently paradoxical.

3 ps between factors was complex and sometimes paradoxical.

4 R (F-IRKO) had a 95% reduction in WAT, but a paradoxical 50% increase in BAT with accumulation of lar

5 = 30 breaths/min or use of accessory muscles/paradoxical abdominal movements).

6 ment-inhibitory potential, rationalizing the paradoxical ability of the BRC repeats to either stabili

7 rom non-pathogenic microbes, including their paradoxical ability to masquerade as one another, is cri

8 ated with ATP7A inactivation in tissues with paradoxical accumulation of copper (i.e. renal epithelia

9 The results reveal a paradoxical acetylation-mediated molecular clutch that t

10 mechanistic questions as illustrated by the paradoxical action and side effects of RAF inhibitors.

11 Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety

12 re we show that ERK5 kinase inhibitors cause paradoxical activation of ERK5 transcriptional activity

13 quaternary architecture illustrates how the paradoxical activation of Raf by kinase inhibitors refle

14 inhibitors (vemurafenib/PLX4720, RAFi) cause paradoxical activation of the MAPK pathway in BRAF-fusio

15 of hyperproliferative skin conditions due to paradoxical activation of the mitogen-activated protein

16 Heidorn and colleagues report that paradoxical activation of the RAF-RAS-MEK-ERK pathway by

17 ough the bulk of the cortex shows wake-like, paradoxical activation.

18 Analogous to its paradoxical activity in lung development, GATA6 expressi

19 a2AR) agonists, but their chronic use causes paradoxical adverse effects.

20 based differences do not seem to explain the paradoxical age-based racial disparities after trauma ob

21 onal activity and glucose balance control to paradoxical and detrimental.

22 anticancer drug paclitaxel (Taxol) exhibits paradoxical and poorly understood effects against slow-g

23 Targeted therapies elicit seemingly paradoxical and poorly understood effects on tumor immun

24 ork offers a mechanistic explanation for the paradoxical antitumorigenic roles of E+P in breast cance

25 These data suggest that taking the paradoxical approach of inhibiting rather than activatin

26 s stabilised by inhibitor binding suggests a paradoxical approach to the targeted treatment of protei

27 poson activity and altogether illustrate the paradoxical arms race between genome evolution and stabi

28 The presence of such displays is paradoxical as in their absence the male should be able

29 olution of sexual traits is often considered paradoxical as, although they enhance reproductive succe

30 This degeneracy is paradoxical, as it reduces specificity and REs are extre

31 se the biological mechanisms underlying this paradoxical association are poorly understood, we aimed

32 The paradoxical association between overweight and mortality

33 fat and SCD-1 activity may contribute to the paradoxical association of lower fasting and postprandia

34 idiopathic pulmonary fibrosis, we reverse a paradoxical association of the strong susceptibility gen

35 A, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life

36 common properties of MGEs, and the seemingly paradoxical bacterial behaviours of transformation and c

37 l-cycle duration, up to second cousins, seem paradoxical because ancestral correlations decay rapidly

38 This is paradoxical because the prevalent theory is that IFN-I i

39 the existence of the EMT in sarcomas appears paradoxical because these cancers are, by definition, me

40 steroid treatment in muscular dystrophy are paradoxical because these steroids are also known to tri

41 t dilute nectar in bat-pollinated plants as "paradoxical" because bats prefer concentrated nectar, bu

42 s, most ecological models which exhibit such paradoxical behavior depend on the presence of exogenous

43 The perplexing and paradoxical behavior of KACh channels is due to the intr

44 The observed paradoxical behaviour of these and other commonly encoun

45 . targeting like-minded individuals) creates paradoxical behaviour such as non-transitive dynamics.

46 , NMe-Phe(4), Gly-ol(5)]-enkephalin produces paradoxical behavioural responses: early-phase analgesia

47 rins are a molecular mediator of hormesis, a paradoxical beneficial effect of low- or moderate-level

48 e, providing a potential novel mechanism for paradoxical BRAF activation.

49 A paradoxical brain state displaying asynchronous firing p

50 Escaping narwhals displayed a paradoxical cardiovascular down-regulation (extreme brad

51 dentify an eosinophil-mediated mechanism for paradoxical caspofungin activity and support the future

52 lular striatal acetylcholine and D2R-induced paradoxical ChI excitation, which was reversed by mAChR

53 Infant gliomas have paradoxical clinical behavior compared to those in child

54 our findings provide an explanation for the paradoxical clinical-outcomes after ADT, possibly due to

55 r fluctuating selection; hence, the somewhat paradoxical coexistence of both in the same population m

56 parsimonious explanation for the apparently paradoxical combination of disinhibition and severe akin

57 This paradoxical combination of increased energy demands alon

58 Paradoxical components act bifunctionally in signaling n

59 and inactivation would produce consistent or paradoxical conclusions regarding interneurons' computat

60 Recent works have pointed to some of the paradoxical consequences of such a unidirectional range,

61 We traced the paradoxical control of visual temporal sensitivity to ro

62 Connectivity analyses revealed paradoxical coupling in prefrontal-amygdala circuits, in

63 tivated protein C (APC) and thrombin elicits paradoxical cytoprotective and cytotoxic signaling respo

64 in male and female Gnal (+/-) mice, but the paradoxical D2R-mediated ChI excitation was retained and

65 These paradoxical data implicate that additional acetylation m

66 in sensitivity specifically in EC leads to a paradoxical decline in endothelial function, mediated by

67 ed an upstream regulator of Pak2, we found a paradoxical decrease in baseline activation of CDC42 in

68 es in interneuron density in FCD may lead to paradoxical depolarization of pyramidal cells.

69 ing an eye is unnecessary for producing this paradoxical deprivation effect: interocular suppression

70 sthetic-induced unconsciousness, and (3) the paradoxical, desynchronized brain state in deep anesthes

71 ced GI Hyperalgesia, is characterized by the paradoxical development of or increases in abdominal pai

72 e ratio of single units with anticipated and paradoxical discharge was similar in HFrEF (18:7) and co

73 No cases of paradoxical drug-related neurological worsening were rec

74 In both four-population models, the paradoxical effect implies not too strong recurrent exci

75 munity in times of starvation and exerting a paradoxical effect in overnutrition.

76 This paradoxical effect may reflect a disruption of homeostat

77 ividual neuronal responses could explain the paradoxical effect of CBZ at the network level.

78 beta production by PAI-1, which explains the paradoxical effect of PAI-1 deficiency in promoting card

79 Simulations predict a paradoxical effect that should be revealed by patterned

80 f activity of L4 FS neurons contradicts the "paradoxical effect" predicted in networks stabilized by

81 udy provides a potential explanation for the paradoxical effects of CBZ on epileptiform activity.SIGN

82 Overall, our study describes paradoxical effects of CPO of an RNA virus on viral repl

83 the underlying mechanisms of these seemingly paradoxical effects of lithium, in which fine-tuned regu

84 To explain the paradoxical effects of PIN1 on p27 levels and cell cycle

85 CPO of an RNA virus for a mammalian host has paradoxical effects on virus replication and the adaptiv

86 Additionally, average paradoxical effects result only with transgenic, not vir

87 Dishevelled levels in Drosophila embryos has paradoxical effects, promoting the ability of limiting l

88 dient with reduced (classical) or preserved (paradoxical) ejection fraction.

89 found both pulmonary embolism due to DVT and paradoxical embolism due to existing patent foramen oval

90 This finding supports the hypothesis that paradoxical embolism is an important mechanism of ischem

91 The authors hypothesized that paradoxical embolism through patent foramen ovale (PFO)

92 that might result in bidirectional shunt and paradoxical embolism.

93 onsequently, cause serious conditions due to paradoxical embolus.

94 PA receptor upregulation, it also produces a paradoxical enhancement in membrane AMPA receptor subuni

95 The paradoxical enhancement in phytoplankton near an island-

96 to selectively target tumors and prevent the paradoxical ERK activation could increase the feasibilit

97 It is unknown whether "paradoxical" ERK activation occurs after sorafenib thera

98 In some cases, there is evidence for paradoxical escape from defensin neutralization or enhan

99 properties in tauopathy model mice despite a paradoxical evolution of biomarker signatures usually as

100 This paradoxical exacerbation of prenatal Zika virus exposure

101 ry is in a chronic state of hypoxia owing to paradoxical excess activity of monoamine receptors (5-HT

102 targets, and neurons affecting sedation and paradoxical excitation in vivo in zebrafish.

103 of central nervous system depressants cause paradoxical excitation in zebrafish.

104 hetic drugs, but how these compounds produce paradoxical excitation is poorly understood.

105 c models of human dystonia, the D2R-mediated paradoxical excitation of ChIs is shared and is caused b

106 l acetylcholine by in vivo microdialysis and paradoxical excitation of cholinergic interneurons (ChIs

107 The paradoxical excitation was caused by overactive muscarin

108 ain and motor activity-a phenomenon known as paradoxical excitation.

109 ds and identified dozens of hits that caused paradoxical excitation.

110 bitory transmitter but can sometimes produce paradoxical excitatory effects through synaptic networks

111 Paradoxical expansion of tuberculous lesions during ther

112 The paradoxical face-color percept could be explained by a B

113 g elevated state anxiety may account for the paradoxical facilitation of performance on tasks that re

114 A somewhat paradoxical finding was that reduced [(18)F]FSPG cellula

115 Here we resolve these paradoxical findings and show that the capacity of LYVE-

116 ure challenge will be to understand how such paradoxical findings can be reconciled and how GR ultima

117 Organoid models therefore clarify the paradoxical findings from SELECT and demonstrate that Vi

118 Here, we discuss these paradoxical findings in the context of CTLA-4-mediated l

119 Although speculated that such paradoxical findings may be explained by impaired hypoxi

120 The paradoxical findings of decreased Hla in vitro but incre

121 These paradoxical findings suggest that the approach for asses

122 l proliferation into account may explain the paradoxical findings that aging itself and slowed aging

123 rmine the neural mechanisms underlying these paradoxical findings, we trained monkeys to discriminate

124 hypothetical mechanisms that may explain our paradoxical findings.

125 noncoding ribonucleic acids (RNAs) remained paradoxical for a long time.

126 The regulatory mechanisms of this paradoxical function of the cervix are unknown.

127 potential prognostic marker. To address such paradoxical function, our study investigated how SHOC2 i

128 e mechanisms employed for their numerous and paradoxical functions that ultimately link environmental

129 echanism requiring CD8(+) T cells, which was paradoxical given the drug's reported ability to inhibit

130 henotype induced by MPL P106L belongs to the paradoxical group, where low MPL levels on platelets and

131 Regardless of the clinical relevance of this paradoxical growth effect, understanding the specific ac

132 station of the amoebae natural host, and the paradoxical hMDMs' pro-inflammatory response is likely a

133 g to heterodimerization with C-Raf causing a paradoxical hyperactivation of MAPK pathway.

134 We examined the paradoxical hypothesis that the alpha-receptor inverse a

135 in vitro and in vivo, demonstrating a dual, paradoxical immune modulatory effect and supporting the

136 Incidence of paradoxical immune reconstitution inflammatory syndrome

137 to anti-TNF therapy, and some patients show paradoxical immune side effects, which are poorly unders

138 These data indicate a paradoxical impact of obesity on cancer.

139 once perplexed biologists because it seemed paradoxical in a Darwinian world.

140 ain why the net effect of mTOR inhibitors is paradoxical in the acquired models of epilepsy.

141 hich they can bore have remained elusive and paradoxical, in that, as oxygenic phototrophs, cyanobact

142 Importantly, we observed a paradoxical increase in ERK signaling in mid-neurogenesi

143 ivation of inhibitory interneurons elicits a paradoxical increase in inhibitory synaptic input.

144 This paradoxical increase in lysosomal biogenesis by mTORC1 w

145 nificant decrease in calbindin neurons and a paradoxical increase in neurons estimated by NeuN staini

146 ic antioxidant supplementation can produce a paradoxical increase in oxidative stress associated with

147 analgesia) and opioid-induced hyperalgesia (paradoxical increase in pain with opioid administration)

148 Depletion of collagen V led to a paradoxical increase in post-infarction scar size with w

149 reduced EGP significantly but gave rise to a paradoxical increase in postprandial PG excursion, which

150 mals had decreased crypt apoptosis but had a paradoxical increase in villus apoptosis compared with s

151 to intra-VTA infusions of AMPA, suggesting a paradoxical increase in VTA AMPA receptor responsiveness

152 l patterns of nutrition-related disease: the paradoxical increase of chronic disease with increased f

153 thromboembolic-related adverse events but a paradoxical increased hemorrhagic risk.

154 ke recent physiological findings that showed paradoxical increases in pharyngeal muscle responsivenes

155 cells, larger basal cell bodies and nuclei, paradoxical increases in proliferation markers, and exce

156 Unlocking the mechanistic detail of these paradoxical innate immune events will be crucial for und

157 adiponectin secretion as the explanation for paradoxical insulin receptoropathy-related hyperadiponec

158 tivity, associative learning deficits, and a paradoxical inversion of psychostimulant responses.

159 faced by regulatory agencies, and highlight paradoxical lessons that emerge.

160 Using these sex-specific cutpoints, paradoxical LF was independently associated with increas

161 Paradoxical LF/HG was associated with higher mortality f

162 tors (SSRIs) improve mood in adults but have paradoxical long-term effects when administered during p

163 5 (27%) NF with low gradient (LG), 246 (17%) paradoxical low flow (LF)/HG, and 238 (16%) LF/LG.

164 f patients with low ejection fraction (LEF), paradoxical low flow (PLF), and normal flow (NF) after a

165 eft ventricular ejection fraction, including paradoxical low-flow (i.e., stroke volume index <35 ml/m

166 lar ejection fraction <50%) and LG (CLF-LG); paradoxical low-flow (left ventricular ejection fraction

167 Background Paradoxical low-flow (LF) severe aortic stenosis (AS) wi

168 ients (63.5%); CLF-LG, 689 patients (19.6%); paradoxical low-flow-LG, 247 patients (7.0%); and normal

169 05) but was not statistically different from paradoxical low-flow-LG: 33.6% (P=0.18).

170 assified as follows: (1) HG; (2) CLF-LG; (3) paradoxical low-flow-LG; and (4) normal-flow-LG.

171 nt of LTP-like cortical plasticity forming a paradoxical LTD in comparison to HS.

172 K inhibitor is co-administered, as it blocks paradoxical MAPK activation.

173 accelerates cutaneous wound healing through paradoxical MAPK activation; addition of a mitogen-activ

174 ic melanoma, resistance has emerged through "paradoxical MEK/ERK signaling" where transactivation of

175 HIFI explains how labor can progress despite paradoxical metabolic challenge, and provides a new mech

176 This is associated with a paradoxical mitochondrial hyper-function and increased o

177 Laryngoscopy revealed paradoxical movement of the vocal cords, and a diagnosis

178 ion, high pro-apoptotic NOXA expression, and paradoxical, MYCN-driven upregulation of NOXA.

179 K(+)VGluT3(+)INTs is amplified, they promote paradoxical network hyperexcitability which may be relev

180 The causes of this paradoxical observation - that unconserved machinery und

181 This seemingly paradoxical observation suggests that either patients wi

182 , separation-of-function allele resolves the paradoxical observation that a fast-evolving essential g

183 se data help explain, in part, the seemingly paradoxical observations that CD8(+) T cells displaying

184 This seemingly paradoxical occurrence has led to speculation of a 'Janu

185 nite-element analysis demonstrated that this paradoxical OMTC result in vimentin-KO MEFs could be att

186 in mediators of Th1-Th2 immunity, which have paradoxical or no impact.

187 monalities with those of slow-wave sleep and paradoxical or rapid eye movement sleep, respectively.

188 occurs during active or attentive waking and paradoxical or rapid eye movement sleep.

189 vation during active or attentive waking and paradoxical or rapid eye movement sleep.

190 Thus, a paradoxical outcome of the successful remediation of aci

191 ulin-resistant states are characterized by a paradoxical pathogenic condition in which the liver appe

192 established by the parasite could lead to a paradoxical pathogenic role for Tregs.

193 Because of paradoxical pathway activation, both agents were demonst

194 These results suggest that paradoxical percepts reflect tradeoffs between sensitivi

195 Studies seeking to understand the paradoxical persistence of malaria in areas in which sur

196 d body weight may resolve previous seemingly paradoxical pharmacological results and might deepen our

197 This seemingly paradoxical phenotype is due to lower glucose utilizatio

198 This paradoxical phenotype results from an ectopic interactio

199 This paradoxical phenotype was caused by a dampened inflammat

200 f XAL2 in SAM transitions and the apparently paradoxical phenotypes of XAL2 and other MADS-box (SOC1,

201 To explain these paradoxical phenotypes, we hypothesized that an insulin-

202 In ALM layer five and S1, the PV response is paradoxical: photoexcitation reduces their activity.

203 tic pruning pathways-that were linked to the paradoxical positive genetic association between educati

204 tory-dependence of STP the model generated a paradoxical prediction: that inactivation of inhibitory

205 This paradoxical preference may account for the frequency wit

206 These data illustrate the paradoxical pro-tumor role for CXCR3 in lung immunobiolo

207 resident commensal-specific T cells harbor a paradoxical program characterized by a type 17 program a

208 mit TSC-associated tumour growth but lead to paradoxical promotion of tumour cell survival upon treat

209 ng TFPI prevents aPL signaling, indicating a paradoxical prothrombotic role for TFPI.

210 activator (PA), PA inhibitor-1 (PAI-1) has a paradoxical protumorigenic role in cancer, promoting ang

211 ffusion-weighted imaging (DWI) for assessing paradoxical puborectalis syndrome (PPS) in patients with

212 s of complex ocular motor disorders, such as paradoxical pupillary constriction to darkness, benign t

213 single SNPs in isolation may account for the paradoxical racial risk of AF among white individuals an

214 This centromere drive can explain the paradoxical rapid evolution of both centromere DNA and c

215 (cSCC) within weeks of treatment, driven by paradoxical RAS/RAF/MAPK pathway activation.

216 ) patients in the 6-week group experienced a paradoxical reaction compared with 39 (25.3%) patients i

217 The diagnosis was a paradoxical reaction to antituberculosis treatment; afte

218 logical complications (eg, hydrocephalus and paradoxical reactions) and of hyponatraemia, which frequ

219 sis but appears inessential for tuberculosis paradoxical reactions.

220 (SFK) signaling or mutant NRAS, which drive paradoxical reactivation of the pathway.

221 ) and controls (27:5), whereas LBPP elicited paradoxical reflex excitation in a greater proportion of

222 as a KSHV-susceptible model to overcome the paradoxical refractoriness of B cell lines to experiment

223 l origin in development, and define WT1 as a paradoxical regulator of aHSCs induced by injury but sup

224 that this distinction can create a seemingly paradoxical relationship between 3C and FISH, both in mi

225 This paradoxical relationship has made it challenging to teas

226 A paradoxical relationship was observed between clinical o

227 Here we report that this paradoxical requirement for the simultaneous induction o

228 To trace the origin of this paradoxical resilience, we systematically tuned the micr

229 Cancer drug addiction is a paradoxical resistance phenomenon, well-described in MEK

230 Paradoxical response (PR) is defined as a clinical or ra

231 Hatzivassiliou and colleagues examined the paradoxical response of RAF-WT tumors to treatment with

232 xidative stress, HPbetaCD addition induces a paradoxical response, increasing cholesterol accumulatio

233 al androgen (SPA) concentrations can produce paradoxical responses leading to PC growth inhibition.

234 endent risk for major arrhythmic events, and paradoxical responses to beta-adrenergic agents.

235 However, while lymphoblasts show paradoxical responses to neurons and glia, patient-deriv

236 ced network models predict that ISNs produce paradoxical responses to perturbation, but experimental

237 This paradoxical result can occur in a regulated population w

238 This seemingly paradoxical result was linked to NEMO-mediated regulatio

239 In this issue, Carneiro et al. explain these paradoxical results by showing that manipulations affect

240 nly are these results reminiscent of classic paradoxical results from evolutionary game theory, but t

241 This can lead to paradoxical results.

242 mple potential resolutions to the previously paradoxical results.

243 Climate plays a paradoxical role as cold glacier thinning and retreat pr

244 e mbp mRNA in oligodendrocytes, indicating a paradoxical role for the retrograde dynein/dynactin comp

245 Here, we characterize and reconcile the paradoxical role of ghrelin in the acquisition of fearfu

246 ms of NET formation, as well as the apparent paradoxical role of neutrophils and NETs in host defense

247 s, several recent reports have highlighted a paradoxical role of perisomatic-targeting parvalbumin-po

248 or research in heart attacks has suggested a paradoxical role of the social environment: those who ar

249 These data demonstrate the paradoxical role that GPC-1 plays in prostate cancer cel

250 Because of the seemingly paradoxical SCFA activities in regulating T cells, we in

251 However, this paradoxical self-reactivity correlated with these VH4-34

252 pecifically, the X chromosome has acquired a paradoxical sex-biased function by redistributing gene c

253 nd with high affinity to BRAF and that block paradoxical signaling in malignant melanoma cells occurr

254 key feature of this signaling network is the paradoxical signaling loop.

255 and the spine volume can be described using paradoxical signaling loops.

256 ctivity-associated health risks are somewhat paradoxical, since evolutionary pressures tend to favor

257 Thus, a paradoxical situation develops in which the high affinit

258 This paradoxical situation reflects our lack of knowledge abo

259 In order to investigate this seemingly paradoxical situation, 2-MIB stability was reinvestigate

260 CSDS affected numerous endpoints, including paradoxical sleep (PS) and slow-wave sleep (SWS), as wel

261 e similarly more activated during waking and paradoxical sleep (PS; aka REM) than during slow-wave sl

262 o occurs during natural attentive waking and paradoxical sleep in association with theta activity and

263 -12 Hz rhythm associated with locomotion and paradoxical sleep reflecting synchronization of neuronal

264 l state instability, abnormal transitions to paradoxical sleep, and cataplexy, hallmarks of narcoleps

265 ing different profiles during locomotion and paradoxical sleep.

266 h theta activity during attentive waking and paradoxical sleep.SIGNIFICANCE STATEMENT Neurons in the

267 Slow-wave sleep and rapid eye movement (or paradoxical) sleep have been found in mammals, birds and

268 n-noxious warm and cold temperatures cause a paradoxical, sometimes painful, sensation of burning hea

269 for the pervasiveness of this theoretically paradoxical strategy.

270 In this review we focus on this paradoxical stress response, which provides cells with u

271 Unexpectedly, Syn-2 knockout mice exhibited paradoxical superior glucose homeostasis resulting from

272 onfirm a novel form of excess adiposity with paradoxical suppression of leptin expression, and sugges

273 predictions, including the counterintuitive (paradoxical) suppression of inhibitory firing in respons

274 We show that this paradoxical TAP-dependency is indirect and reflects the

275 PLWH with TB disease are at risk of the paradoxical TB-associated immune reconstitution inflamma

276 specific T-cell responses and development of paradoxical TB-IRIS on antiretroviral therapy (ART).

277 s in IL-6, is associated with development of paradoxical TB-IRIS.

278 It seems paradoxical that the heterodimer should bind more strong

279 awkish participants that were exposed to the paradoxical thinking intervention expressed less support

280 ectiveness of a "real world," multichanneled paradoxical thinking intervention, with messages dissemi

281 Based on the paradoxical thinking principles, the intervention involv

282 in the form of ventricular septal defect and paradoxical thromboembolism.

283 Fifty years ago, Michel Jouvet used the term paradoxical to define REM sleep because of the simultane

284 th ageing that could be exploited to improve paradoxical triggering and other changes in protective s

285 Startling reports described the paradoxical triggering of the human mitogen-activated pr

286 ffective in both preventing and treating the paradoxical tuberculosis-associated immune reconstitutio

287 The immunopathogenesis of paradoxical tuberculosis-associated immune reconstitutio

288 promote their invasive behaviors, leading to paradoxical tumor aggression after therapy.

289 Our data also revealed paradoxical tumor suppressor functions for Abl kinases i

290 6-bisphosphate aldolase B (Aldob) leads to a paradoxical up-regulation of glucose metabolism to favor

291 However, a paradoxical upregulation of proteins involved in cellula

292 Phenotypic resistance was partly mediated by paradoxical upregulation of RNA polymerase in response t

293 of RAF kinases can induce a dose-dependent "paradoxical" upregulation of the downstream mitogen-acti

294 the DePAC project was that a widely-held but paradoxical view that palliative care and dying patients

295 d resistance, often in complex and seemingly paradoxical ways.

296 were included (14 infectious/unmasking and 8 paradoxical), with an overall incidence rate of 0.74 cas

297 H) often have behavioral effects that appear paradoxical within the framework of optimal choice theor

298 lesions were the composite risk factors for paradoxical worsening of TB SLC (OR 7.555, 95% CI: 1.78-

299 reater risk of poor therapeutic response and paradoxical worsening.

300 We hereby report a paradoxical yet translational epigenetic regulation of p