ライフサイエンスコーパス: paraplegia

1 ighting the genetic heterogeneity of spastic paraplegia.

2 stent with a diagnosis of hereditary spastic paraplegia.

3 neuron diseases, such as hereditary spastic paraplegia.

4 cur in the perioperative period resulting in paraplegia.

5 ctor to early autonomic symptoms and spastic paraplegia.

6 ental defects and a familial form of spastic paraplegia.

7 dolescent-onset, isolated hereditary spastic paraplegia.

8 n associated with a familial form of spastic paraplegia.

9 the most common cause of hereditary spastic paraplegia.

10 and validated with two patients with chronic paraplegia.

11 ure, renal and splenic microinfarctions, and paraplegia.

12 gene mutated in a form of hereditary spastic paraplegia.

13 mutated in the axonopathy hereditary spastic paraplegia.

14 inked to SPG13, a form of hereditary spastic paraplegia.

15 ith the clinical phenomenon of delayed onset paraplegia.

16 oo-common clinical syndrome of delayed-onset paraplegia.

17 hic lateral sclerosis and hereditary spastic paraplegia.

18 lved in MND, particularly hereditary spastic paraplegia.

19 ble immediate treatment to prevent permanent paraplegia.

20 the morbidity and mortality associated with paraplegia.

21 g endograft treatment suffered postoperative paraplegia.

22 common autosomal dominant hereditary spastic paraplegia.

23 clinical presentation of progressive spastic paraplegia.

24 ) gene, which co-segregated with the spastic paraplegia.

25 complex but virtually eliminates the risk of paraplegia.

26 w" is simple but has an unacceptable risk of paraplegia.

27 ith a 50% probability of resultant permanent paraplegia.

28 with 22/38 (6.6% of cohort) sustaining total paraplegia.

29 pass support (P =.0005) were associated with paraplegia.

30 nd is associated with a reduced incidence of paraplegia.

31 e KIF5A, in a family with hereditary spastic paraplegia.

32 on was a pure lower limb predominant spastic paraplegia.

33 P1 can cause pure autosomal dominant spastic paraplegia.

34 sal treatment strategy in hereditary spastic paraplegia.

35 the chief gene mutated in hereditary spastic paraplegia.

36 e show progressive motor symptoms, a spastic paraplegia.

37 system for understanding hereditary spastic paraplegia.

38 e most frequent metabolic hereditary spastic paraplegia.

39 a diverse set of complex hereditary spastic paraplegias.

40 nesin family member 5A (KIF5A) cause spastic paraplegia 10.

41 R-shaping proteins, in families with spastic paraplegia 12 (SPG12).

42 ice-site) associated with hereditary spastic paraplegia 4 (HSP-SPG4) (SPG4:OMIM#182601) has suggested

43 ns in which cause autosomal-dominant spastic paraplegia 4 [SPG4]) have been described, their origins

44 cellular activities (m-AAA) protease spastic paraplegia 7 (SPG7) has been recently implicated as eith

45 d a necessary and conserved role for spastic paraplegia 7 (SPG7) in Ca(2+)- and ROS-induced PTP openi

46 dity included rupture (4.7%), stroke (4.7%), paraplegia (8.5%), bowel ischemia (7%), acute renal fail

47 PG5) is a rare subtype of hereditary spastic paraplegia, a highly heterogeneous group of neurodegener

48 with various subtypes of hereditary spastic paraplegia, a highly heterogeneous group of neurodegener

49 entified in patients with hereditary spastic paraplegias, a diverse group of neurological disorders c

50 g a later step, result in hereditary spastic paraplegia accompanied by intellectual deficits.

51 tations in AP5Z1 and presenting with spastic paraplegia accompanied by neuropathy, parkinsonism and/o

52 atures of AP-4-associated hereditary spastic paraplegia across the age spectrum our results will faci

53 Autosomal-dominant pure hereditary spastic paraplegia (AD-HSP) is characterized by the degeneration

54 isease autosomal dominant-hereditary spastic paraplegia (AD-HSP).

55 ic occlusion is critical in the mechanism of paraplegia after aortic cross-clamping and may provide t

56 Paraplegia after epidural catheter occurred once.

57 There was no clinical evidence of paraplegia after IRE ablation.

58 changes that may be adaptive in non-stepping paraplegia after SCI.

59 Permanent paraplegia after thoracic and thoracoabdominal aortic an

60 many candidate genes for hereditary spastic paraplegia also have central roles in lipid-droplet form

61 istance in activities of daily living, makes paraplegia an important target for prevention.

62 n genes usually associated with pure spastic paraplegia and also in the Parkinson's disease-associate

63 , we screened a cohort of hereditary spastic paraplegia and cerebellar ataxia cases (n = 618) for mut

64 ic neurological diseases (hereditary spastic paraplegia and cerebellar ataxia).

65 to be a frequent cause of hereditary spastic paraplegia and cerebellar ataxia.

66 se gene for a new complex hereditary spastic paraplegia and confirm that etherlipid homeostasis is im

67 ease the risk of spinal cord ischemia and/or paraplegia and consists of permissive hypertension after

68 gene data could explain a report of spastic paraplegia and dementia cosegregating in a family with d

69 who presented with bilateral lower extremity paraplegia and development of rhabdomyolysis of the para

70 ected subjects exhibited progressive spastic paraplegia and distal muscle wasting.

71 suffering from SPG4-type hereditary spastic paraplegia and explain why single amino acid exchanges l

72 EAE-related mortality, nonremitting spastic paraplegia and hemorrhagic inflammatory lesions.

73 logical disorders such as hereditary spastic paraplegia and hereditary sensory neuropathy.

74 improvement in rates of major complications, paraplegia and in-hospital mortality.

75 infantile-onset ascending hereditary spastic paraplegia and juvenile primary lateral sclerosis, sugge

76 ith an autosomal dominant hereditary spastic paraplegia and lacking mutations in known hereditary spa

77 repair was 4.9%; combined mortality, stroke, paraplegia and RRT outcome was 12.8%.

78 intellectual disability, progressive spastic paraplegia and short stature, born to a consanguineous f

79 is a common theme between heritable spastic paraplegia and some inherited epilepsies.

80 rophic lateral sclerosis, hereditary spastic paraplegia and spinal muscular atrophy.

81 candidate key pathway for hereditary spastic paraplegias and cerebellar ataxias and thus prioritize t

82 ovement disorders such as hereditary spastic paraplegias and cerebellar ataxias remain genetically un

83 s with autosomal dominant hereditary spastic paraplegias and lacking mutations in known causative gen

84 of disease progression in hereditary spastic paraplegias and other MNDs.

85 frontotemporal dementia, hereditary spastic paraplegia, and 1-2% of familial amyotrophic lateral scl

86 tic paraparesis mimicking hereditary spastic paraplegia, and a multiple sclerosis-like illness.

87 rophic lateral sclerosis, hereditary spastic paraplegia, and cerebellar degenerations.

88 lasia, retardation, adducted thumbs, spastic paraplegia, and hydrocephalus).

89 ated in the human disease hereditary spastic paraplegia, and its link to WASH suggests that misregula

90 , and dental) and limb dysmorphisms, spastic paraplegia, and neurodegeneration.

91 neurodegenerative disease hereditary spastic paraplegia, and of ichthyin, mutated in autosomal recess

92 oxia, multiple sclerosis, hereditary spastic paraplegia, and others.

93 c neuropathy, complicated hereditary spastic paraplegia, and select hereditary metabolic neuropathies

94 e found in patients with ichthyosis, spastic paraplegia, and severe neurodevelopmental defects.

95 on locus for mutations in hereditary spastic paraplegias, and katanin are related microtubule-severin

96 leads to childhood-onset hereditary spastic paraplegia (AP-4-HSP): SPG47 (AP4B1), SPG50 (AP4M1), SPG

97 ta, rates of procedural success, stroke, and paraplegia appeared similar, while those for major compl

98 Hereditary spastic paraplegias are a clinically and genetically heterogeneo

99 The hereditary spastic paraplegias are a heterogeneous group of degenerative di

100 Hereditary spastic paraplegias are a large, diverse group of neurological d

101 Hereditary spastic paraplegias are heterogeneous neurological disorders cha

102 Hereditary spastic paraplegias are inherited neurological disorders charact

103 ed in autosomal recessive hereditary spastic paraplegia (ARHSP).

104 s and autosomal recessive hereditary spastic paraplegias (ARHSPs) are clinically and genetically hete

105 dominant pure or complex hereditary spastic paraplegia, as well as in two sporadic patients.

106 as a complicated form of hereditary spastic paraplegia, associated with mutation in the ethanolamine

107 aplegia, while all CI/R patients experienced paraplegia before bypass use.

108 ave been shown to cause a Hereditary Spastic Paraplegia called NTE-related Motor-Neuron Disorder.

109 axons, and support a model in which spastic paraplegia can be caused by impairment of axonal the SER

110 G)1 to -57], over half of hereditary spastic paraplegia cases are caused by pathogenic mutations in f

111 ols of previously unknown hereditary spastic paraplegia causative genes and subtypes, we performed wh

112 is an autosomal recessive hereditary spastic paraplegia caused by mutation in the spartin (SPG20) gen

113 Mutations in PNPLA6 also cause human spastic paraplegia characterized by motor neuron degeneration.

114 hese patients were upgraded to an incomplete paraplegia classification.

115 Hereditary spastic paraplegias comprise a group of clinically heterogeneous

116 Paraplegia continues to complicate thoracoabdominal aort

117 hese patients included dementia with spastic paraplegia, corticobasal degeneration syndrome, and stro

118 linked to diseases such as familial spastic paraplegia, developmental delay with premature death, an

119 We tested the hypothesis that paraplegia differentially increases blood pressure relat

120 Congestive heart failure, paraplegia, dyspnea at rest, and reoperation are associa

121 cord injury, stiff-person syndrome, spastic paraplegia, dystonia and Parkinson disease.

122 sorders, particularly the hereditary spastic paraplegias, emphasizing the importance of proper ER mor

123 veral causative genes for hereditary spastic paraplegia encode proteins with intramembrane hairpin lo

124 orders of ganglioside biosynthesis result in paraplegia, epilepsy, and intellectual disability.

125 A 23-year-old man who had paraplegia from a C7-T1 subluxation as a result of a mot

126 Paraplegia from spinal cord ischemia is a devastating co

127 Spastic paraplegia gene 11(SPG11)-linked hereditary spastic para

128 ommon autosomal recessive hereditary spastic paraplegia gene products, the SPG15 protein spastizin an

129 Mutations in the Spastic Paraplegia Gene11 (SPG11), encoding spatacsin, cause the

130 veral loci known collectively as the spastic paraplegia genes (SPGs).

131 s in a number of other known complex spastic paraplegia genes, including five in SPG7 (5/97), four in

132 taxia type 2, ataxia telangiectasia, spastic paraplegia, giant axonal neuropathy, and fumarate hydrat

133 ore, the life expectancy of individuals with paraplegia has increased to near that of able-bodied ind

134 Paraplegia has significant medical, social, and financia

135 our experience, no episodes of postoperative paraplegia have occurred with the use of this technique.

136 Complex recessive spastic paraplegias have in the past been frequently associated

137 scular diseases including hereditary spastic paraplegia, hereditary sensory neuropathy type 1, and no

138 neurodegeneration, FAHN), hereditary spastic paraplegia (HSP type SPG35) and leukodystrophy (leukodys

139 RLIN2) are known to cause hereditary spastic paraplegia (HSP) and cerebellar ataxia.

140 milar problems that cause hereditary spastic paraplegia (HSP) and Charcot-Marie-Tooth type 2 (CMT2) d

141 and lower motor neurons, hereditary spastic paraplegia (HSP) and distal hereditary motor neuropathy

142 al recessive (AR) complex hereditary spastic paraplegia (HSP) and juvenile onset amyotrophic lateral

143 Two syndromes - hereditary spastic paraplegia (HSP) and mycobacterial disease - thus occurr

144 rebellar ataxia (HCA) and hereditary spastic paraplegia (HSP) are scarce.

145 is an autosomal recessive hereditary spastic paraplegia (HSP) caused by frameshift mutations in the S

146 Hereditary spastic paraplegia (HSP) comprises a group of clinically and gen

147 e-Tooth type 2 (CMT2) and Hereditary Spastic Paraplegia (HSP) depending on the affected neurons: peri

148 Hereditary spastic paraplegia (HSP) describes a heterogeneous group of gene

149 Hereditary spastic paraplegia (HSP) describes a heterogeneous group of gene

150 tosomal-dominant gene for hereditary spastic paraplegia (HSP) in 10 families that are of diverse geog

151 Hereditary spastic paraplegia (HSP) is a collection of neurological disorde

152 Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease c

153 Complex hereditary spastic paraplegia (HSP) is a genetic disorder that causes lower

154 Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder that is

155 Hereditary spastic paraplegia (HSP) is a neurological syndrome characterize

156 The commonest cause of hereditary spastic paraplegia (HSP) is mutation in the spastin gene.

157 es of Atlastin-1 found in Hereditary Spastic Paraplegia (HSP) patients show similar ER phenotypes, su

158 Hereditary spastic paraplegia (HSP) type 2 is a proteolipid protein (PLP1)-

159 cause autosomal dominant hereditary spastic paraplegia (HSP) type SPG8.

160 subunits cause a form of hereditary spastic paraplegia (HSP) with intellectual disability.

161 rumpellin, or REEP1 cause hereditary spastic paraplegia (HSP), a disease characterized by axonal dege

162 ative diseases, including hereditary spastic paraplegia (HSP), a disorder characterized by spasticity

163 utosomal dominant form of hereditary spastic paraplegia (HSP), a motor-neurological disorder manifest

164 ranched ER morphology and hereditary spastic paraplegia (HSP), a neurodegenerative disease characteri

165 the most common cause of hereditary spastic paraplegia (HSP), a neurodegenerative disease that affli

166 n patients suffering from hereditary spastic paraplegia (HSP), a neurodegenerative disorder affecting

167 ns of various genes cause hereditary spastic paraplegia (HSP), a neurological disease involving dying

168 ve been reported to cause hereditary spastic paraplegia (HSP), although their impact at the cellular

169 , Multiple Sclerosis (MS) Hereditary Spastic Paraplegia (HSP), and Huntington's Disease (HD).

170 have been associated with hereditary spastic paraplegia (HSP), autosomal-recessive cerebellar ataxia

171 e-Tooth disease (CMT) and Hereditary Spastic Paraplegia (HSP), but the mechanism of its involvement i

172 In hereditary spastic paraplegia (HSP), the axons of cortical motor neurons de

173 ffect in humans with pure hereditary spastic paraplegia (HSP).

174 tosomal recessive form of hereditary spastic paraplegia (HSP).

175 the most common cause of hereditary spastic paraplegia (HSP).

176 xon degenerative disease, hereditary spastic paraplegia (HSP).

177 tin and atlastin, lead to hereditary spastic paraplegia (HSP).

178 the most common cause of hereditary spastic paraplegias (HSP).

179 The hereditary spastic paraplegias (HSPs) (SPG1-29) comprise a group of inherit

180 The hereditary spastic paraplegias (HSPs) are a genetically and clinically hete

181 The pure hereditary spastic paraplegias (HSPs) are a group of conditions in which th

182 Hereditary spastic paraplegias (HSPs) are a group of diseases caused by cor

183 Hereditary spastic paraplegias (HSPs) are a group of genetically heterogene

184 Hereditary spastic paraplegias (HSPs) are a large, genetically diverse grou

185 The hereditary spastic paraplegias (HSPs) are a rare and heterogeneous group of

186 The hereditary spastic paraplegias (HSPs) are characterized by spasticity of th

187 Hereditary spastic paraplegias (HSPs) are clinically and genetically hetero

188 The hereditary spastic paraplegias (HSPs) are genetic conditions characterized

189 Hereditary spastic paraplegias (HSPs) are genetically driven disorders with

190 The hereditary spastic paraplegias (HSPs) are genetically heterogeneous disorde

191 The hereditary spastic paraplegias (HSPs) are heterogeneous neurodegenerative d

192 Hereditary spastic paraplegias (HSPs) are neurodegenerative motor neuron di

193 ly of genes implicated in hereditary spastic paraplegias (HSPs) is quickly expanding, mostly owing to

194 Hereditary spastic paraplegias (HSPs), a group of neurodegenerative disorde

195 EEP1) are associated with hereditary spastic paraplegias (HSPs).

196 ne of several complicated hereditary spastic paraplegias (HSPs).

197 Hereditary spastic paraplegias (HSPs, SPG1-46) are inherited neurological d

198 Hereditary spastic paraplegias (HSPs; SPG1-45) are inherited neurological d

199 Hereditary spastic paraplegias (HSPs; SPG1-48) are inherited neurological d

200 Hereditary spastic paraplegias (HSPs; SPG1-76 plus others) are length-depen

201 acking mutations in known hereditary spastic paraplegia implicated genes.

202 jor complication rate was 1.7 +/- 2.3%, with paraplegia in 0.4 +/- 0.0%.

203 Paraplegia in both the SHR and WKY rats increased heart

204 In sharp contrast, paraplegia in the SHR increased systolic (6%) and diasto

205 far the most common cause of complex spastic paraplegia in the UK, with severe and progressive clinic

206 Paraplegia in the WKY rats reduced systolic (-4%) and di

207 ures, severe developmental delay and spastic paraplegia, in whom whole-genome sequencing revealed com

208 013) on acute complicated type B AD, stroke, paraplegia, in-hospital mortality and follow-up mortalit

209 These data demonstrate that paraplegia increased BP-CVD risk factors in normotensive

210 RMS in three unrelated patients with spastic paraplegia, intellectual disability, nystagmus, and obes

211 gia gene 11(SPG11)-linked hereditary spastic paraplegia is a complex monogenic neurodegenerative dise

212 Hereditary spastic paraplegia is a highly heterogeneous group of neurogenet

213 Clinical data showed that spastic paraplegia is accompanied by a number of other features,

214 pure, autosomal dominant hereditary spastic paraplegia is caused by mutation in the ATL1 gene encodi

215 rm of autosomal recessive hereditary spastic paraplegia is caused by mutations in the SPG11/KIAA1840

216 nerative disease that in addition to spastic paraplegia is characterized by childhood onset cognitive

217 Pure hereditary spastic paraplegia is characterized by length-dependent degenera

218 as either 'pure' or 'complex' where spastic paraplegia is complicated with additional neurological f

219 er limb spasticity, or complex where spastic paraplegia is complicated with additional neurological f

220 lity and morbidity associated with permanent paraplegia justifies the risks and uncertainties associa

221 inary retention as prodromes of irreversible paraplegia may allow earlier diagnosis and treatment in

222 ossibly of other forms of hereditary spastic paraplegia may involve perturbation of neuronal anterogr

223 uscular hypotonia that progressed to spastic paraplegia, microcephaly, foot deformity, decreased musc

224 the main regulator of the hereditary spastic paraplegia microtubule severing enzyme spastin.

225 ces similar phenotypes of hereditary spastic paraplegia (mitochondrial dysfunction and defects in lip

226 al defects of an atypical hereditary spastic paraplegia mutant, ATL1-F151S, that is impaired in its n

227 Stroke and paraplegia occurred each in 8.0%, and endoleak was diagn

228 Paraplegia occurred in four (12%) of the no bypass group

229 Importantly, the impact of paraplegia on BP-CVD risk factors was greater in the SHR

230 ive disorder mainly characterized by spastic paraplegia, optic atrophy and neuropathy (SPOAN).

231 e unusual combination of early-onset spastic paraplegia, optic atrophy, and neuropathy.

232 Thirty-five patients had paraplegia or paraparesis (5.4%).

233 l aortic aneurysm repair), and there were no paraplegias or strokes.

234 nction were more likely to have irreversible paraplegia (P < 0.01), despite presenting with a monopha

235 . 22 minutes, P <.0001) and a higher rate of paraplegia/paresis (30% vs. 2%, P =.01) as compared to t

236 ypass in the repair of BAI, the incidence of paraplegia/paresis has fallen.

237 hts into the pathology of hereditary spastic paraplegia, particularly how mutations in multiple, conv

238 linico-genetic work-up of hereditary spastic paraplegia, particularly in dominant cases, as the assoc

239 crotubule cytoskeleton in hereditary spastic paraplegia pathogenesis.

240 m mutations identified in hereditary spastic paraplegia patients.

241 uld not be excluded, and 29 sporadic spastic paraplegia patients.

242 sonism, muscle weakness, neuropathy, spastic paraplegia, personality/behavioral problems, and dystoni

243 fied as a complex form of hereditary spastic paraplegia, present in families from Kuwait, Italy and t

244 Here, we show that the hereditary spastic paraplegia protein M1 Spastin, a membrane-bound AAA ATPa

245 nstration of a role for a hereditary spastic paraplegia protein or ichthyin family member in a specif

246 2) and Bhlhb5 (mutated in Hereditary Spastic Paraplegia), providing a molecular handle to investigate

247 decreased coordination, widespread asthenia, paraplegia, quadriplegia, and sensory impairment.

248 ogression rate of 0.56 points on the Spastic Paraplegia Rating Scale per year was slightly lower than

249 linical severity was assessed by the Spastic Paraplegia Rating Scale.

250 Hereditary spastic paraplegias refer to a heterogeneous group of neurodegen

251 eries of 97 index cases with complex spastic paraplegia referred to a tertiary referral neurology cen

252 Paraplegia remains a devastating complication of thoraci

253 ment, and the postoperative complications of paraplegia, renal failure, and pulmonary insufficiency.

254 ariables including congestive heart failure, paraplegia, reoperation, dyspnea at rest, nongastric ban

255 rization of patients with hereditary spastic paraplegias represents progressive spasticity, exaggerat

256 Paraplegia resulting from ischemia is a catastrophic com

257 Troyer syndrome, a recessive form of spastic paraplegia resulting in muscle weakness, short stature,

258 metabolism account for approximately 80% of paraplegia risk and intercostal blood flow accounts for

259 al aneurysm repair for factors that affected paraplegia risk including aneurysm extent, acuity, cardi

260 ion for the last 3 years further reduced our paraplegia risk index by 75%.

261 The paraplegia risk index declined from 0.20 to 0.05 (P < 0.

262 (IRP) using a highly accurate (r(2) > 0.88) paraplegia risk index we developed and published previou

263 This suggests a limit to paraplegia risk reduction in thoracoabdominal endograft

264 previously demonstrated an 80% reduction in paraplegia risk using hypothermia, naloxone, steroids, s

265 erging field support this prediction of high paraplegia risk with thoracoabdominal branched endograft

266 injuries has reduced the rates of death and paraplegia seen with open surgical treatment in the past

267 neurodegenerative disease hereditary spastic paraplegia, severs microtubules.

268 The hereditary spastic paraplegias (SPG1-33) comprise a cluster of inherited ne

269 mutated in patients with hereditary spastic paraplegia, SPG11 and SPG15.

270 drome, and three forms of hereditary spastic paraplegia, SPG11, SPG15 and SPG49 caused by SPG11, ZFYV

271 s cause specific types of hereditary spastic paraplegia (SPG28 and SPG54, respectively), and the yeas

272 ntified in both a form of hereditary spastic paraplegia (SPG35) and a progressive familial leukodystr

273 The early onset hereditary spastic paraplegia SPG3A is caused by mutations in the atlastin/

274 ildhood-onset and complex hereditary spastic paraplegia: SPG47 (AP4B1), SPG50 (AP4M1), SPG51 (AP4E1)

275 mal development with childhood-onset spastic paraplegia, spinal lesion, and optic atrophy.

276 cal resection and there was no postoperative paraplegia, stroke, or myocardial infarction.

277 rm of autosomal-recessive hereditary spastic paraplegia termed AP-4-deficiency syndrome.

278 es disease mechanisms for hereditary spastic paraplegia that involve dependence of the microtubule cy

279 osis and its differentiation from hysterical paraplegia, the second transverse myelitis and its conse

280 Prior to irreversible paraplegia, these patients presented with prodromes of f

281 , ranging from muscular dystrophy to spastic paraplegia to a childhood blinding disorder to bone defo

282 Motor signs developed ascending from spastic paraplegia to tetraplegia and pseudobulbar palsy in the

283 Using a mouse model of hereditary spastic paraplegia type 2 due to a null mutation of the myelin P

284 Using spastic paraplegia type 4 (SPG4, the most frequent HSP subtype)

285 Spastic paraplegia type 5 (SPG5) is a rare subtype of hereditary

286 estigation; recent studies show that spastic paraplegia type 5, a progressive neuropathy, is caused b

287 Spastic paraplegia types 4 (prevalence, 0.91 per 100,000 populat

288 Using a rat model of ischemic paraplegia, we examined the expression of spinal AMPA re

289 ns cause a common form of hereditary spastic paraplegia, we suggest ER-shaping defects as a neuropath

290 utosomal dominant form of hereditary spastic paraplegia, which is a retrograde axonopathy primarily c

291 the use of bypass, no CI/R patient developed paraplegia, while all CI/R patients experienced parapleg

292 paired via clamp-and-sew technique developed paraplegia, while none of the seven CI/R patients repair

293 s with adult onset leukodystrophy or spastic paraplegia with early onset of urinary symptoms and spin

294 , and predominant complex hereditary spastic paraplegia with marked cognitive impairment, without any

295 ed to autosomal recessive hereditary spastic paraplegia with thin corpus callosum and axonal peripher

296 se of autosomal recessive hereditary spastic paraplegia with thin corpus callosum and peripheral axon

297 ings were neurogenic bladder (100%), spastic paraplegia with vibration loss (90%), and axonal neuropa

298 set, slowly progressive, complicated spastic paraplegia, with normal or near-normal psychomotor devel

299 centrifugal pump to reduce the incidence of paraplegia without the risk of systemic anticoagulation

300 essive type of cerebellar ataxia and spastic paraplegia, without intellectual disability.