ライフサイエンスコーパス: parent-of-origin effect

1 loci for asthma and AR while accounting for parent-of-origin effect.

2 logarithm of odds (LOD) 2), with a prominent parent-of-origin effect.

3 rted association in the region, again with a parent-of-origin effect.

4 es this pathway through a previously unknown parent-of-origin effect.

5 on of any tSNP to affected offspring or of a parent-of-origin effect.

6 phytic genes, some of which are subject to a parent-of-origin effect.

7 nner explicable by genome dosage rather than parent of origin effects.

8 /control studies and allows the detection of parent-of-origin effects.

9 igator may wish to look further for possible parent-of-origin effects.

10 ed lethality and directly test for loci with parent-of-origin effects.

11 rinted and six non-imprinted genes that show parent-of-origin effects.

12 an genome, providing insights into potential parent-of-origin effects.

13 at reside at nonimprinted loci but that show parent-of-origin effects.

14 portance, it is crucial to account for these parent-of-origin effects.

15 alignment of pulmonary veins (ACD/MPV), with parent-of-origin effects.

16 requent mosaicism, inconsistent activity and parent-of-origin effects.

17 imary insulin resistance and HCC with strong parent-of-origin effects.

18 disease (AD) pathology and whether there are parent-of-origin effects.

19 ence for any susceptibility locus subject to parent-of-origin effects.

20 provide insight into maternally mediated and parent-of-origin effects.

21 5, 62% transmission, P = 7 x 10(-5)) with no parent-of-origin effects.

22 of genetic and environmental mechanisms for parent-of-origin effects.

23 ility risk, on the basis of such evidence as parent-of-origin effects.

24 The likelihood formulations model parent-of-origin effect and allow for incorporation of a

25 susceptibility is characterized by maternal parent-of-origin effects and increased female penetrance

26 shown to influence disease severity, display parent-of-origin effects and interact with a major envir

27 t-offspring "trio" design was used to assess parent-of-origin effects and population stratification.

28 action of IDDM2 is complicated, however, by parent-of-origin effects and possible allelic heterogene

29 ee-generation pedigrees allowed us to assess parent-of-origin effects and the timing of insertion eve

30 maternal versus paternal transmission rates (parent-of-origin effects) and nontransmission rates (non

31 suggest an important role for methylation in parent-of-origin effects, and by inference parental impr

32 Maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 are u

33 igated maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 in SL

34 candidate genes for complex conditions where parent-of-origin effects are involved, including Alzheim

35 paternal X chromosome, revealing that these parent-of-origin effects are not strain-specific.

36 Parent-of-origin effects are prominent at some of the lo

37 Parent-of-origin effects are unexpectedly common in comp

38 ct4 on CHR X, was demonstrated with a strong parent-of-origin effect associated with the paternal gen

39 However, the molecular basis for the parent-of-origin effect associated with trinucleotide re

40 2 microdeletion region, suggesting potential parent-of-origin effects associated with this genomic di

41 19q12 loci as RET-dependent modifiers, and a parent-of-origin effect at RET.

42 We found suggestive evidence of a parent-of-origin effect at the ABO locus by analyzing th

43 e a further characterization of the possible parent-of-origin effects at the 17q11 locus that were pr

44 multinomial modeling approach for estimating parent-of-origin effects at the test SNP.

45 consequent interest in seeking evidence for parent-of-origin effects at these loci.

46 Several phenomena can cause parent-of-origin effects, but the best characterized is

47 vidence that nonimprinted genes can generate parent-of-origin effects by interaction with imprinted l

48 Parent-of-origin effects can be modified by the environm

49 Our findings show that parent-of-origin effects can evolve by co-option of the

50 ased when analyzed with a model allowing for parent-of-origin effects, compared with analyses that as

51 r offspring point to quantitative epigenomic parent-of-origin effects confounding classical Mendelian

52 Parent-of-origin effects create differences in gene expr

53 a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the databas

54 These data strongly refute a parent-of-origin effect for 1p deletions in NB and exclu

55 backcross scheme that exploited a paternal, parent-of-origin effect for a X-linked gene (Gct4) that

56 linear models can be used to estimate these parent-of-origin effects for a broad class of phenotypes

57 We analyzed parent-of-origin effects for these variants, along with

58 hybrids that showed differential phenotypes (parent-of-origin effect) for CG or DT were selected for

59 Parent-of-origin effects have been difficult to screen f

60 Parent-of-origin effects have been reported for type 2 d

61 Although parent-of-origin effects have been reported in honey bee

62 Antagonistic parent-of-origin effects have only rarely been described

63 hould provide a powerful diagnostic tool for parent of origin effects in the study of aneuploidy, imp

64 No parent-of-origin effect in allelic expression was found

65 We sought to investigate the parent-of-origin effect in childhood allergic diseases.

66 dering ascertainment models when testing for parent-of-origin effect in complex diseases.

67 ed a likelihood-based method for testing for parent-of-origin effect in complex diseases.

68 of genetic analyses, taking into account the parent-of-origin effect in families ascertained through

69 Furthermore, the lack of parent-of-origin effect in LQT syndrome appears to be du

70 The difference in risk suggests a maternal parent-of-origin effect in multiple sclerosis susceptibi

71 A new study uncovers a surprising parent-of-origin effect in telomere length inheritance,

72 0 other entries describe a range of reported parent-of-origin effects in animals.

73 enome activation and might help to elucidate parent-of-origin effects in early human development.

74 to the sexual dimorphism in EAE and paternal parent-of-origin effects in female mice, raising the pos

75 Thus, our study reveals parent-of-origin effects in heritable insulin resistance

76 urther research on familial transmission and parent-of-origin effects in LOAD.

77 500 genes exhibit statistically significant parent-of-origin effects in maize endosperm tissue, but

78 This study confirms parent-of-origin effects in the association with type 2

79 testing for maternally mediated effects and parent-of-origin effects in the same framework.

80 fie and mea mutations also cause parent-of-origin effects, in which the wild-type materna

81 We also observe two types of parent-of-origin effects, including classical imprinting

82 In this study, we questioned whether parent-of-origin effects influence EAE, using reciprocal

83 For example, both allelic variation and parent-of-origin effects influence the thymic expression

84 Methods are presented for incorporation of parent-of-origin effects into linkage analysis of quanti

85 This parent-of-origin effect is due to Gsalpha imprinting in

86 The parent-of-origin effect is important in understanding th

87 A maternal parent-of-origin effect is seen near KCNQ1.

88 However, the basis for the parent-of-origin effect is unknown.

89 icentromeric region of chromosome 18, with a parent-of-origin effect (linkage was present in pedigree

90 Parent-of-origin effects occur when the phenotypic effec

91 JL Gct4 allele (Gct4(J)) also shows a strong parent-of-origin effect, occurring only when the Gct4(J)

92 nd maternal effects as the cause of apparent parent-of-origin effects of alleles.

93 the molecular mechanism responsible for the parent-of-origin effects of mea mutations on seed develo

94 Thus, parent of origin effects on sharing and linkage to impri

95 SJL mice also showed a parent-of-origin effect on DNA methylation and X gene ex

96 some multicopy genes influences the paternal parent-of-origin effect on EAE susceptibility in female

97 identification and molecular dissection of a parent-of-origin effect on gene expression that might he

98 e plants show that DNA hypomethylation has a parent-of-origin effect on seed size.

99 length inheritance, which also depends on a parent-of-origin effect on telomere elongation in the ea

100 No evidence was found for parent-of-origin effects on allelic transmission.

101 s (PO) and Peromyscus maniculatus (BW) yield parent-of-origin effects on both embryonic and placental

102 45,XO) has suggested that there are X-linked parent-of-origin effects on brain development and cognit

103 -specific ChIP-seq analyses demonstrate that parent-of-origin effects on caste-specific profiles of H

104 s usually result in viable seed that exhibit parent-of-origin effects on endosperm development and fi

105 n, DECREASE IN DNA METHYLATION1, also causes parent-of-origin effects on F(1) seed size.

106 l3 to be paternally imprinted, with profound parent-of-origin effects on gene expression.

107 culatus (BW) and P. polionotus (PO), produce parent-of-origin effects on growth and development.

108 hat non-imprinted genes can generate complex parent-of-origin effects on metabolic traits through int

109 ve trait loci (QTL) showing context-specific parent-of-origin effects on metabolic traits were mapped

110 rinting represents a mechanism through which parent-of-origin effects on offspring development may be

111 n, indicate that fie and mea mutations cause parent-of-origin effects on seed development by distinct

112 t although Brassica oleracea displays strong parent-of-origin effects on seed development, triploid b

113 ing variability could contribute to observed parent-of-origin effects on seed development.

114 ion, we demonstrate that previously reported parent-of-origin effects on standing mRNA levels in Dros

115 and CF28, were found to trigger significant parent-of-origin effects on the age of femoral capital o

116 responding maternal siRNAs could account for parent-of-origin effects on the endosperm in interploidy

117 cies where imprinting is observed, there are parent-of-origin effects on the expression of imprinted

118 epigenetic modification that can result in 'parent-of-origin' effects on phenotypic traits.

119 Most existing methods for investigating parent-of-origin effects operate on a SNP-by-SNP basis a

120 No parent-of-origin effect or somatic instability was obser

121 hole, nor was there evidence for significant parent-of-origin effect (pedigrees with paternal transmi

122 The results suggest that parent-of-origin effects, perhaps including genomic impr

123 another mechanism is needed to explain these parent-of-origin effects phenomena.

124 her than cytoplasmic, signal, resulting in a parent-of-origin effect (POE), in which the phenotype of

125 Parent-of-origin effects (POE) exist when there is diffe

126 The parent-of-origin-effect (POE)-regulated methylome includ

127 Parent-of-origin effects (POEs) occur when the effect of

128 in identifying genetic variants that exhibit parent-of-origin effects (POEs) wherein the effect of an

129 Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised

130 to identify networks of genes through which parent-of-origin effects propagate.

131 ca homologues of Arabidopsis genes linked to parent-of-origin effects revealed conservation of some m

132 rt reviews existing methods for detection of parent-of-origin effects, showing that each can be inval

133 ability, including expansions, deletions and parent-of-origin effects, somatic and early embryonic in

134 ase SHORT SUSPENSOR (SSP) through an unusual parent-of-origin effect: SSP transcripts accumulate spec

135 This parent-of-origin effect stems from transcriptional repre

136 These parent-of-origin effects suggest that the chalazal haust

137 s also primarily caused by genetic loci with parent-of-origin effects, suggesting a possible role for

138 just one) are 'neutralized' with respect to parent-of-origin effects supports the hypothesis that pa

139 n outbred mice, that most phenotypes display parent-of-origin effects that are partially confounded w

140 Parent-of-origin effects thus provide new avenues for in

141 f nearly all genes analyzed, suggesting that parent-of-origin effect was minimal.

142 A parent-of-origin effect was observed, but it was not con

143 Additionally, evidence for parent-of-origin effects was observed.

144 ariance, the expected LOD score was 4.5 when parent-of-origin effects were incorporated into the anal

145 Significant parent-of-origin effects were observed in affected femal

146 Parent-of-origin effects were observed in an Icelandic p

147 Statistically significant (P < 0.05) parent-of-origin effects were seen for association with

148 Thus, parent-of-origin effects were specified within the autos

149 A polymorphism in Fc epsilon RI-beta shows parent-of-origin effects when associated with severe inf

150 indings suggest that divergence in loci with parent-of-origin effects, which is probably driven by ge

151 We found both deletions showed a parent-of-origin effect with 100% embryonic lethality wh

152 had a mutation in TRIM28; there was a strong parent-of-origin effect, with all ten inherited mutation

153 lization (hpf) reveal hundreds of genes with parent-of-origin effects, with queen-destined larvae sho

154 The ability to include parent-of-origin effects within linkage analysis of quan