ライフサイエンスコーパス: patch-clamp recording

1 urpose the electrophysiological technique of patch clamp recording.

2 e neocortical brain slices during whole-cell patch clamp recording.

3 ties of the encoded proteins with whole-cell patch-clamp recording.

4 ransduction, we examined its distribution by patch-clamp recording.

5 s using high-resolution confocal imaging and patch-clamp recording.

6 uences of variants were analyzed in vitro by patch-clamp recording.

7 g and performed whole-cell and cell-attached patch clamp recordings.

8 EK-293 cells using whole-cell and inside-out patch-clamp recordings.

9 oaches in combination with lifted whole cell patch-clamp recordings.

10 ere a method for stable simultaneous octuple patch-clamp recordings.

11 red to wild-type mice could be detected with patch-clamp recordings.

12 es of L5 pyramidal neurons of mouse V1 using patch-clamp recordings.

13 neurons using optogenetic tools and in vitro patch-clamp recordings.

14 ellular calcium measurements, and whole-cell patch-clamp recordings.

15 cks anesthetic TREK-1 currents in whole-cell patch-clamp recordings.

16 ied using immunogold electron microscopy and patch-clamp recordings.

17 a preparation of peripheral nerve slices for patch-clamp recordings.

18 Results from patch-clamp recordings agreed well with cellular assays

19 te mapping techniques with in vitro targeted patch-clamp recordings, allowed identifying a new type o

20 x vivo brain slice, combined with whole-cell patch clamp recording and capillary electrophoresis (CE)

21 We used patch clamp recording and substituted cysteine accessibi

22 evels and general locomotion; (2) whole-cell patch clamp recordings and biocytin labeling to assess e

23 uronal Cl- using both gramicidin, perforated-patch clamp recordings and Cl- imaging.

24 was impaired in eKO mice in single cells in patch clamp recordings and in the intact coronary circul

25 es was analyzed immunohistochemically and by patch clamp recordings and microfluorometry.

26 ical and functional properties, simultaneous patch clamp recordings and optogenetic studies reveal th

27 excitatory neurons, we performed multi-cell patch clamp recordings and Patch-seq on neurons derived

28 Using a combination of whole-cell patch-clamp recording and biochemical analyses in hippoc

29 Using a combination of experimental (patch-clamp recording and Ca(2+) imaging at CA3-CA1 syna

30 sensitization/challenge to induce AIAD, (3) patch-clamp recording and Ca(2+) imaging to examine the

31 Here, using in vitro whole-cell patch-clamp recording and intracellular filling in acute

32 ate cells in the cerebellum using whole-cell patch-clamp recording and photolytic uncaging of RuBi-GA

33 We have assessed, using whole-cell patch-clamp recording and RNA-sequencing (RNA-seq), the

34 itochondrial assays; in addition, using both patch-clamp recording and somatic Ca(2+) imaging, we hav

35 Here, using patch-clamp recording and two-photon Ca(2+) imaging in r

36 We used whole-cell patch-clamp recordings and an optogenetic approach to ch

37 ase by a combination of membrane capacitance patch-clamp recordings and biochemical measurements of s

38 Using patch-clamp recordings and biocytin cell filling in acut

39 Patch-clamp recordings and Ca(2+) imaging demonstrate th

40 Here, we used patch-clamp recordings and confocal and electron microsc

41 Here we have combined confocal microscopy, patch-clamp recordings and light-sensitive channel block

42 Using patch-clamp recordings and membrane capacitance measurem

43 circuitry, we combined multiple simultaneous patch-clamp recordings and neuroanatomical analysis.

44 heterologous expression in mammalian cells, patch-clamp recordings and noise analysis to study and c

45 bination of immunohistochemistry, whole-cell patch-clamp recordings and optogenetic stimulation in hi

46 We examined this question using patch-clamp recordings and optogenetics in olfactory bul

47 ne this, we used a combination of whole-cell patch-clamp recordings and optogenetics to demonstrate t

48 hway-specific retrograde tracing, whole-cell patch-clamp recordings and post hoc cell type identifica

49 used retrograde tracing in combination with patch-clamp recordings and recorded pre- and postsynapti

50 ayers 2/3 of V1 of awake mice using targeted patch-clamp recordings and synchronous local field poten

51 , we used a combination of dual simultaneous patch-clamp recordings and targeted optogenetic stimulat

52 By a combination of patch-clamp recordings and two-photon calcium imaging, w

53 nderlying startle habituation in rats, using patch-clamp recordings and voltage-sensitive dye imaging

54 s were harvested and prepared for whole-cell patch-clamp recording, and in treated rats, this occurre

55 Using patch-clamp recordings, artificial dynamic conductance i

56 Using paired patch-clamp recordings between bipolar cell terminals an

57 Here we used Patch-seq(8) to combine patch-clamp recording, biocytin staining, and single-cel

58 This study used whole-cell patch clamp recordings combined with single-cell labelin

59 Dual soma-axon patch-clamp recordings combined with axonal Na(+) imagin

60 Using whole-cell patch-clamp recordings combined with optogenetics in mal

61 In patch-clamp recordings, compound 21 displayed a signific

62 Cell-attached patch clamp recordings confirmed that perisomatic Ih was

63 Patch-clamp recordings confirmed that KV1-C peptide atte

64 Single-channel patch-clamp recordings confirmed that the human BK chann

65 ologous cells and rodent cortical neurons by patch-clamp recordings, confocal microscopy and immunobl

66 o study these questions, we performed paired patch-clamp recordings, deconvolution analysis, and nume

67 Whole-cell, patch clamp recordings demonstrate that both GABA and gl

68 Whole-cell patch-clamp recordings demonstrate that loss of SIRT1 de

69 Patch clamp recordings demonstrated a reduction of all p

70 Ex vivo patch-clamp recordings demonstrated that the depolarizin

71 monstrated the pipettes' utility in targeted patch-clamp recording experiments and single-cell electr

72 A2 receptor and characterized the mutants in patch-clamp recordings, exposing them to glutamate and u

73 ossal MNs from brain slices using whole-cell patch-clamp recording, followed by dye-filling these sam

74 Thus, we focused on optimizing whole-cell patch-clamp recordings for RVM neurons in animals older

75 We optimized whole-cell patch-clamp recordings for RVM neurons in animals older

76 Patch clamp recordings from auditory brainstem neurons a

77 e endbulb of Held was assessed by whole-cell patch clamp recordings from auditory neurons in mature (

78 e endbulb of Held was assessed by whole-cell patch clamp recordings from auditory neurons in mature (

79 ts of the variant vs. wild type NaV1.1 using patch clamp recordings from channels expressed in Chines

80 In whole-cell patch clamp recordings from cultured rat spinal motor ne

81 Using patch clamp recordings from infralimbic mPFC pyramidal n

82 Patch clamp recordings from layer V pyramidal neurons sh

83 Excised patch clamp recordings from nuclear membranes of DT40 ce

84 We made patch clamp recordings from Purkinje cells in cerebellar

85 We have made patch clamp recordings from Purkinje cells in vivo to id

86 art-brainstem preparation to make whole cell patch clamp recordings from T3-4 SPNs (n = 98).

87 ical stimulation of the efferent fibres with patch clamp recordings from the IHCs to measure efferent

88 Finally, ex vivo patch-clamp recording from pairs of neighboring cortical

89 Using dual patch-clamp recording from synaptically connected rod bi

90 Analysis of simultaneous multiple patch-clamp recordings from 6068 pairs of rat neurons wi

91 e, Simultaneous fluorescence and patch-clamp recordings from a neuron expressing paQuasAr

92 e, we used paired motor neuron target muscle patch-clamp recordings from a rapsyn-deficient mutant li

93 We demonstrate platform validation with patch-clamp recordings from a variety of cells in the mo

94 In whole-cell patch-clamp recordings from acute hippocampal slices, (+

95 Whole-cell patch-clamp recordings from astrocytes further suggest t

96 shed light on these mechanisms, we performed patch-clamp recordings from basal amygdala (BA) neurons

97 Here we use visually targeted patch-clamp recordings from basket cell terminals of mic

98 Moreover, we show in patch-clamp recordings from brain slices that VLPO neuro

99 Patch-clamp recordings from Cabp2(LacZ/LacZ) IHCs reveal

100 Whole-cell patch-clamp recordings from calyx endings were performed

101 Patch-clamp recordings from cortical interneurons suppor

102 We performed patch-clamp recordings from GPe neurons and found that b

103 Acute whole-cell patch-clamp recordings from GrCs in brain slices showed

104 Our patch-clamp recordings from heterologously expressed Gly

105 We performed patch-clamp recordings from hippocampal CA3 pyramidal ne

106 In vitro patch-clamp recordings from L5B pyramidal output neurons

107 Utilizing whole-cell patch-clamp recordings from morphologically identified C

108 Simultaneous patch-clamp recordings from multiple neurons offer the h

109 Whole-cell patch-clamp recordings from neurons in PFC slices reveal

110 Using whole-cell patch-clamp recordings from pyramidal neurons and fast-s

111 ress this issue, we made two-photon targeted patch-clamp recordings from rat TC and TRN neuron dendri

112 Consistently, patch-clamp recordings from retrovirally labeled new gra

113 Targeted patch-clamp recordings from SbC-RGCs under two-photon gu

114 -of-function Fbxl3(Afh) mutation and perform patch-clamp recordings from SCN brain slices across the

115 To test this, we performed patch-clamp recordings from soma and dendrites of rat hi

116 Using whole-cell patch-clamp recordings from spinal motoneurons and inter

117 Patch-clamp recordings from spiny projection neurones (S

118 The first patch-clamp recordings from the dendrites of human neoco

119 ted cardiac myocytes, and performed targeted patch-clamp recordings from the latter.

120 Here, we used dual patch-clamp recordings from turtle vestibular hair cells

121 Using ex-vivo patch-clamp recordings from up to 55 SCs per mouse, we f

122 e depletion to this activation pathway using patch clamp recording, GFP-PLCdelta1-PH imaging and co-l

123 Patch-clamp recording has enabled single-cell electrical

124 While in vivo patch-clamp recording has recently benefited from automa

125 Using a combination of patch clamp recording, immunoblotting, confocal imaging

126 ch-seq, a technique that combines whole-cell patch-clamp recording, immunohistochemistry, and single-

127 a single 24-hr episode of MD and whole-cell patch clamp recording in rat midbrain slices, we show th

128 s in hippocampal CA1 pyramidal neurons using patch clamp recordings in acute slices from mice at diff

129 Patch clamp recordings in GCs reveal that movement is ac

130 cine 1331 to valine) by obtaining whole-cell patch clamp recordings in human embryonic kidney 293T ce

131 This result, which we verified with patch clamp recordings in vitro, demonstrates that neuro

132 ining high-yield and high-quality whole-cell patch clamp recordings in vivo.

133 ke the RVM a challenging area for whole-cell patch-clamp recording in adults.

134 Commensurately, patch-clamp recording in mPFC layer V pyramidal neurons

135 The present study used voltage imaging and patch-clamp recording in slices of rat SC to test the hy

136 e inhibitory drive to PV+ INs using targeted patch-clamp recording in spinal cord slices from adult t

137 lfactory bulb slices and two-photon targeted patch-clamp recording in vivo to characterize the proper

138 Patch-clamp recordings in acute slices showed that, 1 we

139 Moreover, patch-clamp recordings in acute VNO slices reveal that m

140 characterization pipeline using standardized patch-clamp recordings in brain slices and biocytin-base

141 Prior in vitro patch-clamp recordings in brain slices from genetic mous

142 Whole-cell patch-clamp recordings in brain slices revealed that int

143 stimulation in vivo and conducted whole-cell patch-clamp recordings in brain slices to reveal how nan

144 rphin-A on MCPO/SI cholinergic neurons using patch-clamp recordings in brain slices.

145 in HMNs in adult male and female mice using patch-clamp recordings in brain slices.

146 otent role of gap junctions was confirmed in patch-clamp recordings in bulb slices from wild-type and

147 In vivo whole-cell patch-clamp recordings in cat visual cortex revealed sma

148 loping the first robot to perform sequential patch-clamp recordings in cell culture and in vivo witho

149 Moreover, we use whole-cell patch-clamp recordings in combination with local electri

150 In situ patch-clamp recordings in genetic mosaics reveal that Dm

151 aSM)-like activity patterns using whole-cell patch-clamp recordings in HEK293 cells (Cav1.2 alpha1-su

152 stasis examined by fluorescence (fluo-4) and patch-clamp recordings in isolated cardiomyocytes.

153 l of neuropathic pain in Long-Evans rats and patch-clamp recordings in layer II/III pyramidal neurons

154 g these adaptations, we conducted whole-cell patch-clamp recordings in NAc core MSNs of "incubated ra

155 Using whole-cell patch-clamp recordings in posthearing mice, we show that

156 Whole-cell patch-clamp recordings in rat DRG neurons revealed that

157 Whole-cell patch-clamp recordings in RPE derived from human-induced

158 Patch-clamp recordings in slices and RNAscope showed tha

159 sion of HP inputs onto MSNs using whole-cell patch-clamp recordings in slices from adult rats.

160 Whole-cell patch-clamp recordings in spinal cord slices revealed th

161 The present study combines patch-clamp recordings in the intact neonatal rat spinal

162 tsA201 cells were measured using whole-cell patch-clamp recordings in the presence and absence of FF

163 Whole-cell patch-clamp recordings in the spinal cord slice preparat

164 Here, we used patch-clamp recordings in visual cortex of anesthetized

165 With multiple patch-clamp recordings in vitro, we show that the cell s

166 Here we combined whole-cell patch-clamp recordings in vivo and dynamic clamp recordi

167 ntact cell-medium interface using whole-cell patch-clamp recordings in vivo and in vitro.

168 Here we perform dendritic and somatic patch-clamp recordings in vivo combined with optogenetic

169 Using dual patch-clamp recordings in vivo, we reveal that in the pr

170 calbindin-D28k, and calretinin in mice with patch-clamp recording, in vivo physiology, and mathemati

171 However, in vitro patch-clamp recordings indicate 66% (23 of 35) of OVLT n

172 docking, molecular dynamics simulations, and patch-clamp recordings indicate that residues K526 and K

173 Targeted patch-clamp recording is a powerful method for character

174 = 44) and with sclerosis (n = 75) combining patch clamp recording, K(+) concentration analysis, elec

175 size component of the GF looming response in patch-clamp recordings, leaving only the velocity compon

176 We combined whole-cell patch clamp recordings (n = 440) of NMDAR-mediated curre

177 A recent study using whole-cell patch clamp recording of MNs in acute spinal cord slices

178 Using patch clamp recording of olfactory bulb slices in the wh

179 (FRAP), quantitative RT-PCR, and whole cell patch clamp recordings of GFP-encoding Mus musculus nACh

180 We performed whole cell patch clamp recordings of hippocampal neurons to determi

181 re prepared following stress, and whole-cell patch clamp recordings of inhibitory postsynaptic curren

182 Patch clamp recordings of isolated rat vagal neurons sho

183 quantitative PCR (q-PCR), immunostaining and patch clamp recordings of membrane current and voltage,

184 Whole-cell patch clamp recordings of spontaneous miniature postsyna

185 In whole-cell patch clamp recordings of transfected HEK293T cells, cha

186 used high-throughput calcium-flux assays and patch clamp recordings of transiently transfected HEK-29

187 Additionally, we describe the first patch clamp recordings of VENs from neurosurgically-rese

188 Here, in vivo whole-cell patch-clamp recording of excitatory neurons revealed var

189 Applying whole-cell patch-clamp recording of HEK cells, we found that wild-t

190 Here, we used in situ patch-clamp recording of myenteric neurons from mice to

191 purinergic receptor antagonists, whole cell patch-clamp recordings of ATP-induced currents were reco

192 We used in vivo patch-clamp recordings of binaural neurons in the Mongol

193 Here, using whole-cell patch-clamp recordings of CA1 pyramidal neurons in anest

194 Here, through patch-clamp recordings of channel population ensembles a

195 ing measurements in vivo, Ca(2+) imaging and patch-clamp recordings of cultured corneal neurons, and

196 METHODS AND Patch-clamp recordings of cultured neonatal rat ventricu

197 microcircuit was investigated with targeted patch-clamp recordings of DA amacrine cells in TH-RFP mi

198 To test these possibilities, we combined patch-clamp recordings of ependymal cells with immunohis

199 Patch-clamp recordings of excitatory and inhibitory curr

200 spinal cord, allowing visualized whole cell patch-clamp recordings of fluorescent lumbar MN cell bod

201 racking of reinnervation, Ca(2+) imaging and patch-clamp recordings of fluorescent retrogradely label

202 egrees C) temperature, we performed in vitro patch-clamp recordings of hair cells and their afferent

203 Here, using patch-clamp recordings of HEK293 cells heterologously co

204 Patch-clamp recordings of Ih currents in cells expressin

205 f, Simultaneous fluorescence and patch-clamp recordings of inhibitory post synaptic poten

206 roscopy of the prokaryotic homolog GltPh and patch-clamp recordings of mammalian EAATs to determine h

207 We performed whole-cell patch-clamp recordings of medium spiny neurons (MSNs) in

208 Perforated patch-clamp recordings of MOPr-mediated activation of G-

209 Here, we obtained dual patch-clamp recordings of neighboring IO neurons from yo

210 Whole-cell patch-clamp recordings of neurons from male mouse ovBNST

211 We used whole-cell patch-clamp recordings of over 460 neurons to characteri

212 n the mouse brain using electrophysiological patch-clamp recordings of septal neurons.

213 Altogether, patch-clamp recordings of single-photon responses in mou

214 Whole-cell patch-clamp recordings of striatal spiny projection neur

215 to underlie these differences using in vitro patch-clamp recordings of synaptic events and multiscale

216 x slices were prepared enabling simultaneous patch-clamp recordings of up to four labeled corticospin

217 Patch-clamp recordings of ventral CA1 pyramidal cells 24

218 Using patch-clamp recordings on Arabidopsis vacuoles, we obser

219 ned with emergent technologies for automatic patch-clamp recordings, permits automated, in vitro high

220 s (bright-field microscopy with simultaneous patch-clamp recording, phase contrast microscopy, and tr

221 Whole-cell patch-clamp recordings reveal that detection inside the

222 Patch-clamp recordings reveal that exposed MOR23 neurons

223 Patch clamp recordings revealed facilitated opening of C

224 Clomeleon imaging and patch clamp recordings revealed that inhibition of NKCC1

225 Outside-out patch clamp recordings revealed that the maximum Na(+) c

226 Whole-cell patch-clamp recordings revealed increased excitatory and

227 Patch-clamp recordings revealed increased inhibitory syn

228 Patch-clamp recordings revealed that 72% of the thoracic

229 Patch-clamp recordings revealed that anatomical rewiring

230 Ex vivo patch-clamp recordings revealed that EGC subthreshold re

231 Here, we use a combination of paired patch-clamp recordings, serial EM, and large-scale multi

232 opathic pain, in vivo two-photon imaging and patch clamp recording showed initial loss and subsequent

233 Whole cell patch clamp recordings showed that CRF increased inhibit

234 Perforated patch clamp recordings showed that noradrenalin changes

235 Patch-clamp recordings showed that riluzole suppressed s

236 hat combines whole-cell electrophysiological patch-clamp recordings, single-cell RNA-sequencing and m

237 approach included Ca(2+) imaging, whole-cell patch-clamp recordings, skin-nerve and gut-nerve prepara

238 sted, stable, simultaneous quadruple-viguple patch-clamp recording system.

239 s these questions, we developed a perforated patch-clamp recording technique and recorded from single

240 HEK293 cells, and studied p7 channels using patch-clamp recording techniques.

241 Here, we analyze with patch clamp recording the novel mechanisms by which hori

242 Using patch-clamp recordings, this study measures dendritic pr

243 We have used patch clamp recording to identify high affinity Cd(2+) b

244 We used whole-cell patch clamp recording to investigate the effect of chron

245 Here, we use paired patch clamp recording to study neuromuscular transmissio

246 e of the following procedures: 1) whole-cell patch clamp recordings to characterize AMPAR transmissio

247 Here the authors use patch clamp recordings to show that selective tuning of

248 Here, we used patch-clamp recording to measure NMDAR-mediated currents

249 In this study, we use 2-photon-guided patch-clamp recordings to characterize responses of vesi

250 Escherichia coli spheroplasts and performed patch-clamp recordings to characterize SthK gating in a

251 retrograde labeling and in vitro whole-cell patch-clamp recordings to examine the effect of trace fe

252 re, we exploited the high time resolution of patch-clamp recordings to examine the effects of Zn(2+)

253 performed paired motor neuron target muscle patch-clamp recordings to investigate the mechanisms cau

254 Here we used site-directed mutagenesis and patch-clamp recordings to investigate the mechanogating

255 We used dendritic patch-clamp recordings to measure dendritic excitability

256 First, we used whole-cell patch-clamp recordings to measure the physiological chan

257 We used site-directed mutagenesis and patch-clamp recordings to probe the ion channel extracel

258 Here, we use in vivo patch-clamp recordings to show that locomotion can be di

259 We use dendrite-soma dual patch-clamp recordings to show that the strong effect of

260 ws simultaneous presynaptic and postsynaptic patch-clamp recording, to show that the postsynaptic res

261 We used a multi-electrode array, with patch-clamp recordings, to determine a reproducible syna

262 Here, we performed patch-clamp recordings, together with pharmacological an

263 Using paired whole-cell patch-clamp recordings, trains of action potentials at 1

264 terize SbC-RGCs in mice, and target them for patch-clamp recordings under two-photon guidance.

265 We performed whole-cell patch clamp recordings using cultured DRG neurons and ob

266 Patch-clamp recording was used to analyze glutamatergic

267 By combining microscopy and patch clamp recording we demonstrate that activation of

268 , computational fluid dynamics modeling, and patch clamp recording, we discovered that OSNs situated

269 Using patch clamp recordings, we found that co-expression of P

270 Lastly, using gramicidin-perforated patch clamp recordings, we found that the GluK2-mediated

271 Using confocal microscopy and patch clamp recordings, we investigated the relevance of

272 In whole-cell patch clamp recordings, we observed larger macroscopic a

273 olution flow cytometry assays and whole-cell patch clamp recordings, we revealed that the surface den

274 Using perforated patch-clamp recording, we found that optogenetic stimula

275 Using the whole-cell patch-clamp recording, we found that THIK-1 currents wer

276 By performing whole-cell patch-clamp recording, we showed that TMEM16B alters neu

277 With multiple patch-clamp recordings, we found that CeL neurons made c

278 fic transgenic mouse lines, optogenetics and patch-clamp recordings, we found that dentate gyrus cell

279 By paired patch-clamp recordings, we further demonstrate that acut

280 ombining single-cell RNA-seq with whole-cell patch-clamp recordings, we identified Ptgds as a genetic

281 Using whole-cell patch-clamp recordings, we observed a K(+) conductance m

282 Here, using in vitro whole-cell patch-clamp recordings, we show that 5-HT hyperpolarizes

283 Using rabies tracing, calcium imaging, and patch-clamp recordings, we show that corticofugal neuron

284 Using perforated patch-clamp recordings, we show that developing IHCs fir

285 Using a combination of somatic and dendritic patch-clamp recordings, we show that the threshold for L

286 Patch clamp recordings were made from bulbospinal RVLM n

287 Whole cell patch clamp recordings were made from gastric-projecting

288 pseudorabies virus PRV-152) and whole-cell, patch clamp recordings were obtained in brainstem slices

289 -gated Ca(2+) channel currents determined by patch-clamp recording were greater in neurons on stiff s

290 r in male lean and db/db mice and whole-cell patch-clamp recordings were conducted.

291 Whole-cell patch-clamp recordings were made from layer V pyramidal

292 Whole-cell patch-clamp recordings were obtained from Purkinje cells

293 Whole cell patch-clamp recordings were performed on isolated naive

294 First, whole-cell patch-clamp recordings were performed on prepubertal mal

295 Whole-cell patch-clamp recordings were performed to examine the eff

296 a platform for automated two-photon targeted patch-clamp recording, which solves this problem by maki

297 o calculate ion concentration changes during patch-clamp recordings, which validated our experimental

298 Combining patch clamp recording with measurement of PLS, we show t

299 he core nucleus accumbens (NAc) by combining patch-clamp recordings with calcium imaging and optogene

300 We used in vitro whole-cell patch-clamp recordings with laser-scanning photostimulat