ライフサイエンスコーパス: patchy

1 rom multiple higher cortical areas to L1 are patchy.

2 ODCs, and that callosal connections are not patchy.

3 nstructions of palaeo flows and ocean levels patchy.

4 urbed conditions are transient and spatially patchy.

5 entin, and the dentin is hypomineralized and patchy.

6 rphism and unique properties remains largely patchy.

7 knowledge of these molecular motors remains patchy.

8 , but Mef2-dependent reporter activation was patchy.

9 d diffuse inflammation, whereas Wsh mice had patchy accumulations of neutrophils and perivascular acc

10 Adolescent mental health services are patchy across the world.

11 yloid-beta was present as punctate and small patchy aggregates in 71% of AD cases, compared with 22%

12 the core of the lesion was characterized by patchy aggregates of abnormal cells and fiber disorganiz

13 lopecia universalis compared with those with patchy alopecia (OR, 1.22; 95% CI, 1.01-1.48, P = .04).

14 alopecia totalis or alopecia universalis vs patchy alopecia.

15 Given the patchy and asymmetric nature of the malformations, ECCL

16 Initial chest imaging showed bilateral patchy and confluent opacities, a finding consistent wit

17 maging technique for assessing MECV in acute patchy and contiguous infarct caused by obstruction of m

18 s, whereas dorsal stream inputs tended to be patchy and either projected equally to superficial and d

19 isolated hydrothermal vents, which, although patchy and ephemeral, harbor unique chemosynthetic commu

20 apted ant leaves its populations clumped and patchy and its seedlings clustered around the parents in

21 e functionalization and coating by realizing patchy and Janus colloids.

22 Generally, skipjack larvae were patchy and more abundant near PIPA's northeast corner, w

23 r water and nutrients, whose distribution is patchy and often dynamic.

24 enchymal changes were also seen, mostly in a patchy and peribronchiolar distribution.

25 With age, CD8 T cells developed a patchy and stochastic promoter demethylation even in cel

26 The presence of patchy and/or confluent, bandlike ground-glass opacity o

27 ML-IRIS, seen in 92.3% of the patients (with patchy and/or punctuate pattern in 70.8% and 45.8% respe

28 S with nasal polyps along with an irregular, patchy, and decreased expression of the TJ molecules occ

29 NOVA) was found among hyper-autofluorescent, patchy, and hypo-autofluorescent patterns, both in short

30 phenotypic patterns: minimal change, focal, patchy, and speckled.

31 During EVNP, the patchy areas cleared in both kidneys.

32 round-glass and poorly defined nodules, with patchy areas of air trapping, are seen in acute/subacute

33 Ethanol caused stellate lesions with patchy areas of normal myocardium, whereas acetic acid c

34 ks (2.6%), intrachoroidal cavitation (2.2%), patchy atrophy (0.9%), and end-stage MD (0.2%).

35 ully segregate or engage axons and form only patchy basal lamina.

36 Patchy block copolymer micelles with a corona consisting

37 ond-shaped platelet micelles and concentric "patchy" block co-micelles by using seeds of the charge-t

38 north-south density gradient, resulting in a patchy bloom beginning 20 to 30 days earlier than would

39 Syrian hamsters with Ad14p1 caused a marked, patchy bronchopneumonia, whereas hamster infection with

40 Patchy burn patterns that left green, P. ramorum-infecte

41 callosal connections in albino rats are not patchy but instead are distributed homogeneously through

42 ncluding severe peripheral vascular disease, patchy cardiac fibrosis, and hepatic steatosis, was note

43 In embryos with patchy cell cycle behavior due to threshold DNA contents

44 cts combined with high charge and possibly a patchy charge distribution.

45 s and safe as a first-line agent for limited patchy childhood alopecia areata.

46 rioretinal atrophy, but not to the extent of patchy chorioretinal atrophy.

47 Presence of delayed patchy choroidal filling and morphologic and functional

48 Delayed patchy choroidal filling was uncommon at baseline.

49 h disruption of the internal elastic lamina, patchy choroidal inflammation, and birefringent intravas

50 cale bright and dark features, indicative of patchy clouds.

51 y an argument that is generalizable to other patchy colloid systems.

52 Inspired by patchy colloid theory, we propose a general framework by

53 uidance for the conditions at which targeted patchy colloidal assemblies in two and three dimensions

54 Synthetic patchy colloidal particles are often poor geometric appr

55 re we present an experimental realization of patchy colloidal particles based on material independent

56 We show that in squid, patchy colloidal physics resulted from an evolutionary r

57 ation of micrometre- and submicrometre-sized patchy colloids is now efficient, but surface patterning

58 emonstrate sequential assembly of chemically patchy colloids such that their valence differs from sta

59 design of patch shape and symmetry can drive patchy colloids to crystallize in a single, selected mor

60 he assembly of both proteinaceous shells and patchy colloids with dissociable charge groups.

61 sible in several soft matter systems such as patchy colloids.

62 the odor source and acquire an irregular and patchy concentration distribution due to turbulent trans

63 Patchy cone loss was present in two symptomatic carriers

64 hin a contiguous cone mosaic; and pattern 3, patchy cone loss with increased cone spacing.

65 t cortical hypercolumns linked by horizontal patchy connections within the same layer.

66 nd Dodecatheon frenchii) that are endemic to patchy cool cliffs may be glacial relicts whose ranges c

67 lock comicelles of controllable length with "patchy" coronal nanodomains were accessible.

68 iscovered was largely gone, a characteristic patchy covering of hydrozoans on dead portions of the sk

69 -DE LA sites, followed by 41 +/- 12% CFAE at patchy DE and 11 +/- 6% at dense DE regions (p = 0.005 a

70 of continuous CFAE sites occur at non-DE and patchy DE LA sites.

71 osterior left atrium contained predominantly patchy DE.

72 lly active areas, owing in part to a low and patchy density of vent-endemic fauna.

73 DE areas were categorized as dense or patchy, depending on their DE content.

74 terized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associate

75 common autoimmune disease in which acquired patchy depigmentation of skin, hair, and mucous membrane

76 mune disease of the skin causing disfiguring patchy depigmentation of the epidermis and, less commonl

77 vitiligo (GV) is a complex disease in which patchy depigmentation results from autoimmune loss of me

78 ed by antigen-specific T cells, resulting in patchy depigmentation.

79 oimmune disease of the skin characterized by patchy depigmentation.

80 (-/-) neonates have hypo-dysplastic kidneys, patchy depletion of the nephrogenic zone and pockets of

81 thyretin amyloid (ATTR) more commonly showed patchy deposits.

82 cialization; and (ii) assuming that prey are patchy, diet specialization and greater aerobic capacity

83 Patchy, diffuse, or CNV-related atrophy was more common

84 the early onset of lung disease, especially patchy disease such as cystic fibrosis lung disease.

85 y of endomyocardial biopsies (especially for patchy diseases such as lymphocytic myocarditis and sarc

86 Incubation with C. parvum resulted in patchy disruption of the epithelium and, at the surface

87 tions, some neurons have split, enlarged and patchy/distorted RFs.

88 at their pre-synaptic terminals, due to the patchy distribution and short path-lengths observed.

89 ase involved in D1 degradation retaining its patchy distribution in the thylakoid membrane.

90 Within area 3b, reciprocal patchy distribution of anterograde and retrograde labeli

91 Phylogenetic studies revealed a patchy distribution of bacterial serpins incompatible wi

92 elements is the simplest way to explain the patchy distribution of BovB, a long interspersed element

93 These findings help to explain the patchy distribution of CRISPR-Cas immune systems within

94 l segregation could not be attributed to the patchy distribution of habitat or to gross differences i

95 er, comes short of explaining a steady-state patchy distribution of proteins, in face of the transien

96 The overall patchy distribution of specific ACADs across the tree of

97 -overexpressing transgenic lines resulted in patchy distribution of the fluorescence, reminiscent of

98 istory suggests that the beetle requires the patchy distribution of the mutualism between its prey, t

99 The patchy distribution of TPS genes in the eukaryotic domai

100 rijalva basin in southern Mexico and found a patchy distribution pattern of both congeners along a st

101 A patchy distribution portended to a near 3-fold increased

102 this heterogeneity demonstrate that while a patchy distribution reduces the expected number of sand

103 This patchy distribution, coupled with the extreme level of S

104 foraging ranges and their prey often have a patchy distribution.

105 Results Patchy distributions of (19)F signal intensity in the co

106 Moreover, paths in the patchy environment (but not the dispersed environment) s

107 onments revealed that paths generated in the patchy environment were adapted to that environment.

108 ome aquatic species that school or forage in patchy environments experience sufficiently severe range

109 vement in dispersed environments, but not in patchy environments-where search was area-restricted.

110 vior are probably maintained by selection in patchy environments.

111 ally, can be predator-avoidance adaptations; patchy environments; habitat loss; and climate change.

112 ial community composition perhaps due to the patchy, ephemeral, and highly overlapping nature of fine

113 lower endoscopy showing areas of nonspecific patchy erythema.

114 Patchy excitation of Purkinje cells with flanking inhibi

115 Thus V1's most striking long-range features--patchy excitatory connections and sparse inhibitory conn

116 ations (mostly <20 m separation), indicating patchy exposure.

117 ac tissue from 2 related mutation carriers a patchy expression pattern ranging from unchanged to tota

118 subset of adult brain astrocytes, yielding a patchy extracellular matrix pattern.

119 hyper-FAF subgroup and by 0.90 mm(2) in the patchy FAF subgroup.

120 , the central retina was virus-infected in a patchy fashion beginning on day 7 post infection (pi), a

121 -specific region of the human Y and the X in patchy flanking gene-conversion tracts on both chromosom

122 d subtle subcortical microvacuolization, and patchy foci of demyelination with no evident white matte

123 owing males to efficiently locate mates in a patchy food environment.

124 In a patchy foraging environment, assessors adopted more caut

125 We tested groups of sticklebacks in patchy foraging environments that differed in the level

126 deterioration, yet this view is supported by patchy fossil and/or rock evidence for uplifting of the

127 rywhere, this offers a mechanism to generate patchy functional properties in phospholipid membranes.

128 rsistent coat-hair whitening, which preceded patchy hair loss in depigmented areas.

129 The temporal transition of RodZ between patchy/helical and mid-cell localization mimics and depe

130 er simulations to study the self-assembly of patchy heterostructural nanocrystals (HNCs), consisting

131 les quickly (i.e., within hours) organize in patchy, highly inhomogeneous distributions, creating "ho

132 into 3 groups: homogenous hyperfluorescence, patchy hyperfluorescence, and normal hypofluorescence.

133 inflamed Gialpha2-/- colonic mucosa contains patchy hypoxia, with increased crypt expression of the h

134 in the CSF, and the EZ was absent in 9.8 and patchy in 31.7%.

135 ZO-1 reactivity was patchy in Col12a1(-/-), Col14a1(-/-), and compound Col12

136 lustered in the heteromodal areas and rather patchy in distributed regions involving the primary cort

137 and colloidal particles that are chemically patchy in even more complicated fashion has opened a new

138 l gray layer is very thin, the projection is patchy in places where the layer is locally absent.

139 also found that snail distributions were so patchy in space and time that obtaining useful data requ

140 However, as resources become increasingly patchy in time or space, it is unknown how organisms alt

141 the right paratracheal stripe, and scattered patchy increased interstitial markings bilaterally.

142 myopia, and some have retinal dystrophy and patchy increased T2-weighted fluid-attenuated inversion

143 s), in fetal CF pigs, the pancreas exhibited patchy inflammation and acinar atrophy, with progression

144 with a heterogeneous charge distribution and patchy interactions.

145 mic vacuolization in myocytes and in another patchy interstitial fibrosis.

146 lar capillary inflammatory cell margination; patchy interstitial hemorrhage; interstitial edema; and

147 migration of colonic inflammation, worsened patchy intestinal inflammation, and long gross intestina

148 of 33 patients (sensitivity, 93.9%), showing patchy irregular uptake in patients with calcifications

149 For example, patchy, Janus or living crystallization particles have s

150 why-resulting in a large-yet still somewhat patchy-knowledge base.

151 ematical models, Doehl et al. argue that the patchy landscape of parasites in the skin is necessary t

152 In contrast, in patchy landscapes the particular shape of the distributi

153 by confluent right ventricular scarring and patchy left ventricular scarring capable of sustaining a

154 imperfect diagnostic tools have resulted in patchy local disease data, which are not well acknowledg

155 less than a minute, while restoration to the patchy localization pattern is dependent on cell growth

156 clearly distinguishable from the punctate, "patchy" localization patterns of MreB-RFP(SW), even by s

157 lectron microscopy tomography shows that the patchy loss correlates with loss of PSD-95-containing ve

158 Vitiligo is characterized by a patchy loss of inherited skin color affecting approximat

159 mitotic synchrony in cleavage-stage embryos, patchy loss of nuclei in syncytial blastoderms, and cuti

160 l cord tracts; reduced cerebellar foliation, patchy loss of Purkinje cells, multifocal thinning of th

161 lized vitiligo is a common disorder in which patchy loss of skin and hair pigmentation principally ap

162 On day 3, widespread areas of patchy lung consolidation were found on CT, with a drast

163 largely in different patients, suggesting a patchy manifestation pattern of small fiber neuropathy.

164 vaded ecosystems are often found in refugia: patchy, marginal habitats unsuitable to their nonnative

165 Heating resulted first in patchy membranes where L o and L d domains no longer sho

166 Patchy microinfarct, contiguous infarct, and microinfarc

167 athologic findings confirmed the presence of patchy microinfarction.

168 ruction (MVO) zones, and moderately enhanced patchy microinfarcts in border zones, which represent di

169 of acute myocardial infarcts, MVO zones, and patchy microinfarcts simultaneously.

170 erved that FtsZ predominantly localizes as a patchy midcell band, and only rarely as a continuous rin

171 is especially true for species that feed on patchy mobile resources where all group members may loca

172 e are indeed massive sesamoids that employ a patchy mode of ossification of a massive cartilaginous p

173 Our new "patchy" model system opens up the possibility for self-a

174 ignore reservoir species or model them with patchy models by ordinary differential equations.

175 suggest a multimodal mosaic, consisting of a patchy modular network with surrounding extramodular dom

176 go, histology of depigmenting skin reveals a patchy mononuclear infiltrate and single-cell infiltrati

177 highest percentage of RPE cells displayed a patchy mosaic expression pattern, with 50% to 90% of RPE

178 common identity spread over a broad area of patchy mountain environments.

179 hyper-autofluorescent, hypo-autofluorescent, patchy, multifocal, and spoke-like patterns.

180 cterised by sudden pain attacks, followed by patchy muscle paresis in the upper extremity.

181 These patchy nanocolloids have potential applications in funda

182 effective hydrophobicity of amphiphilic or "patchy" nanoglobular systems.

183 les (CMs); however, high-yield generation of patchy nanoparticles remains a challenge.

184 There is new evidence on the patchy nature of celiac disease supporting the practice

185 ic findings revealed ischemic enteritis with patchy necrosis and fibrin thrombi in arterioles (n = 2)

186 ns suggests each highlight the same periodic patchy network throughout the nascent LCIC.

187 Choroidal abnormalities appearing as bright patchy nodules detected by NIR imaging frequently occurr

188 e topographic pattern of CREB regulation was patchy, not continuous, as expected from the actions of

189 ormation as a generalizable strategy to make patchy NPs of various shapes for emergent assemblies and

190 ic swimming strategies of marine bacteria in patchy nutrient seascapes exert strong influence on carb

191 d-type corneas, but labeling was reduced and patchy on IL-1 receptor (IL-1R)-knockout mouse corneas (

192 mputed tomography abnormality was multifocal patchy opacities.

193 g abnormalities, including multiple areas of patchy or diffuse intimal, medial or adventitial abnorma

194 open-field virtual environment, with either patchy or dispersed resource distributions.

195 4-20 in 6 h) and persistent thick clots with patchy or extensive infarction of circumscribed cortex i

196 opic CNV was associated more frequently with patchy or geographic atrophy (P = .019).

197 is widely acknowledged, but evidence remains patchy or inconclusive.

198 n the border of the PML lesion with either a patchy or punctuate appearance in 88.5% of all patients.

199 of contrast-enhancing lesions with either a patchy or punctuate appearance in the border of the PML

200 ing loss (seven with extensive DRs, one with patchy or restricted DRs, and two with no DR) were teste

201 Even though this, rather patchy, organization of brain regions gives us a glimpse

202 Twenty-two patients (22/40, 55%) had patchy parafoveal atrophy and flecks; 8 (20%) had numero

203 erity of toxic effects categorized as early (patchy parafoveal damage shown on field or objective tes

204 ith the protein phase diagram and a tailored patchy particle model, we show that a single temperature

205 re recapitulated by computational results of patchy particle models, validating the identification of

206 tire self-assembly kinetic network of simple patchy particle systems.

207 Janus and patchy particles are emerging as models for studying com

208 The cross-linked poly(styrene)-based patchy particles are fabricated by encapsulation of coll

209 The assembly of patchy particles has made it possible to reconstitute mo

210 as defined by van Blaaderen in 2003 and the patchy particles imagined a few years later.

211 colloidal fusion, for fabricating functional patchy particles in a tunable and scalable manner.

212 can simply, selectively and reversibly join patchy particles into clusters (2D and 3D) and also coll

213 new and nonconventional method of assembling patchy particles into ordered structures.

214 A simple and effective way to make DNA patchy particles is reported.

215 A facile method to synthesize shape-shifting patchy particles on the colloidal scale is described.

216 anisotropic interactions, such as colloidal patchy particles or proteins with multiple binding sites

217 These DNA patchy particles provide direction-selective and thermor

218 For assembly of a designed cluster of patchy particles we find that changing the rotational di

219 The initial concave patchy particles were synthesized in a water suspension

220 pecific directional interactions, so called "patchy particles", are promising candidates for bottom-u

221 ic asymmetrical systems, Janus particles and patchy particles, are capable of undergoing hierarchical

222 potential to impact the design of chromatic patchy particles, colloidal swimmers, and chiral optical

223 ine a scalable strategy for the synthesis of patchy particles, first by designing their surface patte

224 cluster templates from organo-silica hybrid patchy particles.

225 stems of particles with surface patches (or 'patchy' particles) remains a challenge.

226 we treated the proteins as limited-valence (patchy) particles and identified a wetting transition fo

227 homeobox gene Tshz1 is expressed in a unique patchy pattern across the MOE.

228 elps quickly progress a kinetically arrested patchy pattern into the equilibrium striped pattern, whi

229 This multimodal approach identified a patchy pattern of atrophy within the putamen.

230 both species, striatal GluD1-IR displayed a patchy pattern of distribution in register with the stri

231 with retinal pigment epithelium mottling, a patchy pattern of hypoautofluorescent speckles on SW-FAF

232 +/- 0.17, whereas the 9 eyes maintaining the patchy pattern showed a final BCVA of 0.60 +/- 0.37 (P =

233 switches its localization from a dispersed, patchy pattern to an accumulation at the FtsZ ring locat

234 ment epithelium (RPE) damage occurred in the patchy pattern, associated with decreasing BCVA.

235 In the subgroup showing the patchy pattern, the BCVA declined slightly from 0.51 +/-

236 rautofluorescent pattern and 10 eyes (37%) a patchy pattern.

237 Patchy patterns had the highest prevalence.

238 and 45% of ApoE(-/-) mice and corresponding patchy perfusion defects, yet coronary arteries were nor

239 Microangiography and 3D imaging revealed patchy perfusion of Egfl7(-/-) placentas marked by imped

240 ts, and even bacteria, although they exhibit patchy phylogenetic distribution in each kingdom.

241 imilarity across widely diverged species and patchy phylogenetic distribution suggest that they may h

242 others, such as l-rhamnose utilization, have patchy phylogenetic distributions.

243 dyspigmentation at birth followed by further patchy pigment loss during childhood.

244 Using this method, the shape of patchy prisms is varied from small lobed, big lobed, tre

245 MIF is a diffuse and patchy process, appearing as a combination of interstiti

246 se behavior obtainable from a single, highly patchy protein when interactions acting over multiple le

247 This allows the formation of well-defined "patchy" rectangular platelets and platelet block comicel

248 ans, as a 'rule' that evolved in response to patchy resource distributions.

249 to question based on the observation that in patchy resource environments resource-sensitive foraging

250 ategy at exploiting temporally and spatially patchy resources, with most studies focusing on indirect

251 timal for 'blind foragers' to locate sparse, patchy resources.

252 y normal ERGs; OCT and histopathology showed patchy retinal disorganization with pseudorosettes more

253 Stable, patchy RPE loss was observed with a low concentration of

254 lity (P<0.0001 by ANOVA) and in regions with patchy scar (versus endocardial, midwall, epicardial sca

255 transmural as compared with the more erratic/patchy scar patterns seen in other nonischemic cardiomyo

256 e interstitial lung disease characterized by patchy scarring of the distal lung with limited therapeu

257 antitatively, the addition of SES unimers to patchy SEM wCCMs results in a mixture of ABA- and AB-typ

258 Whereas only patchy signs of iron scavenging were observed in white m

259 eral perturbations and is shown to result in patchy silencing.

260 MF may vary from limited patchy skin disease to extensive cutaneous plaque and tu

261 ary disorder characterized by hyperpigmented patchy skin in sun-exposed areas, especially the face.

262 ) is a multisystem disorder characterized by patchy skin lesions, polysyndactyly, diverse cerebral ma

263 combination of asymmetric clinical features, patchy skin manifestations, and neoplastic association p

264 and (2) dermatitis characterized grossly by patchy skin pallor that progressed to variable circular

265 d by FERMT1) and clinically characterized by patchy skin pigmentation and atrophy.

266 ability to block hypoxic vasoconstriction in patchy, small regions of inflammation.

267 Proteins have "patchy" solvent-accessible areas composed of domains of

268 ery difficult to produce, due largely to the patchy spatial and temporal coverage of ground-based SO2

269 pproach lacks a mechanism to ensure that the patchy spheres select the staggered orientation of tetra

270 rons, in vitro and in situ, PIST displayed a patchy subcellular distribution in an area surrounding t

271 of SS4 alone or when fused to GS conferred a patchy subchloroplastic localization similar to that of

272 By genetically inducing a patchy subset of UGS epithelial cells to express excess

273 superficial CK7 immunostaining and positive patchy suprabasilar CK17 staining in the canaliculops ep

274 s that evolve into particles with a range of patchy surface morphologies on addition of a plasticizer

275 As the tube is pulled from a patchy surface, membrane tension increases locally, lead

276 Molecular-dynamics simulations of water on patchy surfaces capture the observed behaviors and point

277 we study the wetting of model compounds with patchy surfaces differing solely in patchiness but not i

278 is idea, we asked if adsorbing enzymes onto "patchy" surfaces composed of adsorbing and nonadsorbing

279 Using patchy switching as an example, we describe conceptual t

280 Patchy switching describes a change in the state of a ne

281 s review, we use a phenomenon referred to as patchy switching to illustrate the interplay of nonlinea

282 roscopy reveals an unexpected discontinuous, patchy synthesis pattern.

283 n-oriented searches, both in homogeneous and patchy target landscapes.

284 ia define the pathognomonic lesion of CTE as patchy tau pathology within neurons and astrocytes at th

285 may design the geometry of string-like rigid patchy templates to promote their efficient and reproduc

286 iacaran deep oceans and helps to explain the patchy temporal record of early metazoan fossils.

287 Each injection produced dense, patchy terminal labeling in a single coherent field with

288 mputational experiments demonstrate how this patchy terrestrial structure, in combination with enhanc

289 oplankton species is often considerably more patchy than that of non-motile species at submetre lengt

290 sponses to concurrent auditory stimuli, in a patchy topography.

291 ermal vent communities, where the habitat is patchy, transient, and often separated by tens or hundre

292 ral types (endocardial, midwall, epicardial, patchy, transmural) of scar were measured in late gadoli

293 leation, growth, and thickness saturation of patchy tribofilms were observed.

294 n successfully finding a mate in a generally patchy urban scenario.

295 show remarkable, yet unexplained fine-scale patchy variation in species composition.

296 d Janus-like vesicles with different shapes, patchy vesicles, and heterogeneous vesicles.

297 ype block co-micelles together with residual patchy wCCMs.

298 Left ventricular scarring was patchy with a predilection for the basal septum, anterio

299 ffects of intergroup competition - is so far patchy, with no clear case where all the relevant assump

300 adolinium-enhanced images in their model was patchy, with small clusters randomly distributed across