ライフサイエンスコーパス: pathogen

1 is an important but difficult to study human pathogen.

2 e for mapping using different strains of the pathogen.

3 rferi, the tick-borne Lyme disease bacterial pathogen.

4 ition and facilitated plant infection by the pathogen.

5 antiviral drugs for this important zoonotic pathogen.

6 crophages to support the iron demands of the pathogen.

7 ptococcus pneumoniae is a devastating global pathogen.

8 itary predator for an indirectly transmitted pathogen.

9 e to Cochliobolus miyabeanus, a necrotrophic pathogen.

10 innate immune response of the larvae to the pathogen.

11 phthora infestans, the infamous Irish famine pathogen.

12 logical shape for C. jejuni as an intestinal pathogen.

13 akuranetin was more effective against fungal pathogens.

14 efense mechanism in mammals against invading pathogens.

15 the host to severe infections with unrelated pathogens.

16 ia by both the normal microbiota and enteric pathogens.

17 g a rapid inflammatory response to microbial pathogens.

18 mpetence, defined as the ability to transmit pathogens.

19 the defense of the airways against bacterial pathogens.

20 tive cytotoxic and humoral responses against pathogens.

21 tes positive for select, clinically relevant pathogens.

22 e those pathways are targeted by human viral pathogens.

23 ta regarding both emerging vectors and their pathogens.

24 ne development against flagellated microbial pathogens.

25 arkable bioprotective activity for biohazard pathogens.

26 repression of T-cell reactivity to unrelated pathogens.

27 against OXA-CRAB as well as SBL-carrying CRE pathogens.

28 to both pneumococcus and unrelated bacterial pathogens.

29 an increased susceptibility to intracellular pathogens.

30 inst bacterial and potentially non-bacterial pathogens.

31 acilitates the study of ticks and tick-borne pathogens.

32 er levels of antibodies against heterologous pathogens.

33 rgently needed to combat multidrug-resistant pathogens.

34 t metabolism and immunity for the benefit of pathogens.

35 raction, trapping, and destruction of motile pathogens.

36 MDA may lead to selection of multiresistant pathogens.

37 reases susceptibility to potential bacterial pathogens.

38 for potato defences against the necrotrophic pathogen A. solani.

39 homodimerization mode in CYP51 from a human pathogen, Acanthamoeba castellanii CYP51 (AcCYP51).

40 se that CLas uses D. citri nymphs mainly for pathogen acquisition and multiplication, and their adult

41 postdrought shrub dominance was higher when pathogens acted as codrivers of tree mortality.

42 Multiple pathogens affect mitochondria dynamics and functions to

43 pplied this approach to examine how a fungal pathogen affected the assembly processes structuring the

44 ato defences against the necrotrophic fungal pathogen Alternaria solani.

45 Campylobacter jejuni is a zoonotic pathogen and is one of the leading causes of human gastr

46 ble protection against diverse intracellular pathogens and can be broadly segregated into distinct ci

47 Blood culture positivity results for true pathogens and contaminants were assessed, along with a s

48 ea, and whether associations between enteric pathogens and death were modified by acute malnutrition.

49 immunity, involved in resistance to selected pathogens and in the regulation of inflammation(1-3).

50 ecline due to a myriad of factors, including pathogens and malnutrition.

51 ifies the association between common enteric pathogens and moderate-to-severe diarrhoea, and whether

52 Humoral immunity to pathogens and other environmental challenges is paramoun

53 rms race between antiviral factors and viral pathogens and provide a new means of targeted attenuatio

54 ingenin was more effective against bacterial pathogens and sakuranetin was more effective against fun

55 us for being vectors transmitting infectious pathogens and source of allergens causing allergic condi

56 g approaches that have been used for various pathogens and study questions, as well as the most commo

57 hanisms behind phage resistance in bacterial pathogens and the physiological consequences of acquirin

58 sion of multidrug-resistant gastrointestinal pathogens and the risk of treatment failures.

59 f the immensely complex relationship between pathogens and their hosts.

60 cell-mediated immunity against intracellular pathogens and tumors.

61 by which mammalian conducting airways expel pathogens and unwanted surface materials from the respir

62 ernative for management of this severe plant pathogen, and relative to chemical fungicides, provides

63 rphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presenc

64 interactions between host, host microbiome, pathogen, and the environment all affect disease outcome

65 community dynamics of microbial mutualists, pathogens, and their plant hosts.

66 estible plant matter, resist colonization by pathogens, and train the developing immune system.(1)(,)

67 homeostasis by clearing damaged organelles, pathogens, and unwanted protein aggregates.

68 y mechanism of protection against many viral pathogens, antibodies mediate additional immune function

69 libraries consisting of as few as one major pathogen antigen.

70 oplasm of infected cells; however, how these pathogens are able to compartmentalize their life cycle

71 ctor-borne, generalist wildlife and zoonotic pathogens are the types of parasites most likely to be a

72 eria encompassing important human and animal pathogens as well as non-pathogenic species such as ecol

73 uired for hGBP1's activity against microbial pathogens, as well as for its antiproliferative and anti

74 ncytial virus (RSV) is the most common viral pathogen associated with acute lower respiratory infecti

75 f PM depolarization and negatively regulates pathogen-associated molecular pattern-triggered immunity

76 ysaccharides (LPS), cytokines and damage- or pathogen-associated molecular patterns (DAMPs/PAMPs) fro

77 Pathogen-associated molecular patterns (e.g., dsRNA) act

78 ed in response to diverse stimuli, including pathogen-associated molecular patterns (PAMPs)(1).

79 tem for a faster and/or stronger response to pathogen attack.

80 Selected pathogens avoid activating NOS2 by concealing key PAMPs

81 xin (NHE) from the neglected human foodborne pathogen Bacillus cereus is an activator of the NLRP3 in

82 stinal anaerobic commensal and opportunistic pathogen Bacteroides fragilis does not synthesize the te

83 anging environmental conditions and emerging pathogen-based diseases.

84 isease chytridiomycosis caused by the fungal pathogen Batrachochytrium dendrobatidis to show how inte

85 The interaction of pathogens between wild and farmed aquatic animal populat

86 In each case, longitudinal assessment of pathogen burden elucidated the temporal sequence of even

87 CD4(+) T cells are critical to fighting pathogens, but a comprehensive analysis of human T-cell

88 anthomonas oryzae pv. oryzae, hemibiotrophic pathogens, but enhanced resistance to Cochliobolus miyab

89 omously attracting, trapping, and destroying pathogens by controlled chemoattractant and therapeutic

90 Clearance of pathogens by Kupffer cells is an important innate immune

91 Median TTR for major respiratory pathogens by organism ranged from 29.2 to 43.9 h for ID

92 formed to confirm the presence of tick-borne pathogens by real-time PCR, and a subset of samples was

93 The adaptive immune system responds to pathogens by selecting clones of cells with specific rec

94 The rise of antimicrobial-resistant pathogens can be attributed to the lack of a rapid patho

95 ly enzyme SOD5 from the opportunistic fungal pathogen Candida albicans have revealed that the active-

96 , Candida tropicalis and the emerging fungal pathogen Candida auris contain a single SOD5-like SOD ra

97 disease pairs suggests that either different pathogens cause the same gross lesions in different spec

98 In 2017, these pathogens caused an estimated 622,390 infections (95% co

99 ocavirus 1 (HBoV1) is one of the significant pathogens causing acute respiratory tract infections in

100 re and specificity among a sampling of plant pathogen Cdc14 homologs.

101 functions, such as encapsulation of invading pathogens, cell-cell fusion in response to foreign bodie

102 The human pathogen Chlamydia trachomatis targets epithelial cells

103 One such pathogen, Chlamydia trachomatis, has a limited capacity

104 ctivities are chain-length dependent, impair pathogen clearance, antagonize phagocyte recruitment, di

105 is an extracellular opportunistic bacterial pathogen commonly associated with infectious complicatio

106 l cells can remember a previous contact with pathogen compounds and respond nonspecifically to reinfe

107 tool for early warning and detection of low pathogen concentrations in water samples.

108 acute and chronic HBV infection to study the pathogen-crosstalk during the different immune phases of

109 of T cell clone sizes with implications for pathogen defense and autoimmunity.

110 incing evidence on the induction of MDSCs by pathogen-derived molecules and inflammatory mediators in

111 Pathogen-derived nucleic acids are crucial signals for i

112 nts and their individual capacity to present pathogen-derived peptides.

113 ccus pneumoniae were the commonest bacterial pathogens detected; atypical bacteria were uncommon.

114 pigs thus providing an approach to emerging pathogen detection that appeals to the swine industry.

115 asites, adding fascinating insight into host-pathogen dialog that may furnish actionable targets for

116 tic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specim

117 They combat pathogens due to their antiviral, antifungal and antibac

118 ii) the opening of niche space for potential pathogens during thermal stress.

119 e surveyed for host immunity, microbiome and pathogen dynamics.

120 omprehension of the mechanisms that regulate pathogen elimination, immunity, and pathology is essenti

121 Throughout the course of infection, many pathogens encounter bactericidal conditions that threate

122 robacteriaceae (CRE) are multidrug-resistant pathogens for which new treatments are desperately neede

123 The highly infectious and zoonotic pathogen Francisella tularensis is the etiologic agent o

124 ut-associated germinal centres from specific-pathogen-free (SPF) mice contain highly dominant 'winner

125 2-AG directly modulates pathogen function by inhibiting virulence programs essen

126 erences, and changes in the concentration of pathogen genes and host-specific fecal markers.

127 Computational analyses of pathogen genomes are increasingly used to unravel the di

128 ingle-nucleotide polymorphisms (SNPs) in the pathogen genomes sourced from host samples.

129 alleles (>20,000) and the complexity of many pathogen genomes.

130 es of phasevarion systems in the major human pathogens Haemophilus influenzae, Neisseria meningitidis

131 ocytogenes is a Gram-positive, intracellular pathogen harboring the surface-associated virulence fact

132 DNA methylation in a fungal pathogen has persisted for millions of years without the

133 systems in multiple human-adapted bacterial pathogens has demonstrated that global changes in methyl

134 So far, 36 fungal pathogens have been authorized for introduction across 1

135 ent deprivation, metal toxicity) and biotic (pathogens, herbivores) stress factors.

136 changes in cellular architecture that favor pathogen-host interactions.

137 of cellular targets that enhances subsequent pathogen-host interactions.

138 el host-pathogen interaction.IMPORTANCE The "pathogen" hypothesis of Alzheimer's disease (AD) propose

139 ens can be attributed to the lack of a rapid pathogen identification (ID) or antimicrobial susceptibi

140 Current technologies focus on pathogen identification that lack rapid testing of the p

141 regulated by both host genetic diversity and pathogen immune evasion.

142 Candida glabratais an opportunistic pathogen in humans, responsible for approximately 20% of

143 ng cause of congenital infection and a major pathogen in immunocompromised individuals.

144 cus or Pseudomonas strains as the underlying pathogen in most cases (48 and 34%, respectively).

145 We found that the co-occurrence of both pathogens in a particular host is not common except in h

146 or of soybean productivity and resistance to pathogens in adverse climates.

147 The method is applicable to plant pathogens in general, to supply epidemiological paramete

148 mmunities, they could serve as opportunistic pathogens in immunocompromised hosts.

149 VDRs in maintaining Paneth cell alertness to pathogens in intestinal disorders.

150 dual PIV serotypes and between PIV and other pathogens in patients with community-acquired pneumonia.

151 cators to signify a health risk from enteric pathogens in sewage-impacted waters.

152 mpetitive barrier against invading bacterial pathogens in the intestinal tract, on the skin or on the

153 Detecting pathogens in trade is critical for preventing their cont

154 particular, several Gram-negative bacterial pathogens including Neisseria meningitidis, Vibrio chole

155 propanol (NP)] against 5 different microbial pathogens including two antibiotic-resistant species [me

156 Opportunistic pathogens, including Aspergillus fumigatus (1.4%) and cy

157 rsistence induced by intracellular bacterial pathogens, including B. abortus Results from this study

158 rom the plant host to filamentous eukaryotic pathogens, including fungi and Phytophthora species.

159 n to have bactericidal activity against many pathogens, including Pseudomonas aeruginosa, Staphylococ

160 n general, heightened immune responses limit pathogen-induced cellular morbidity, which can facilitat

161 killer cells of the human body to eliminate pathogen-infected or tumorigenic cells (i.e., target cel

162 triggers a rapid localized cell death at the pathogen infection sites, termed the hypersensitive resp

163 utes critically to host cell defenses during pathogen infection.

164 s rely on the ability of B cells to remember pathogen infections and respond more vigorously upon rei

165 nsumer-resource systems, alter the course of pathogen infections within a host and enhance the rates

166 ing in response to extracellular stimuli and pathogen infections.

167 However the mechanisms by which periodontal pathogens influence the development of prediabetes/diabe

168 multiplication, and their adults mainly for pathogen inoculation and spread.

169 Many Gram-negative bacterial pathogens interact with mammalian cells by using type II

170 nce of considering 3D cultures to model host-pathogen interaction.IMPORTANCE The "pathogen" hypothesi

171 c processes occurring during host-microbiota-pathogen interactions can favorably or negatively influe

172 n plants and play an essential role in plant-pathogen interactions.

173 lammatory responses that results during host-pathogen interactions.

174 important strategy to better understand host-pathogen interactions.

175 uent reminder of the need to understand host-pathogen interactions.

176 re important for cell-cell communication and pathogen internalization.

177 a GABAergic signaling machinery in the host-pathogen interplay between phagocytes and invasive cocci

178 Phagocytes engulf pathogens into a membrane bound compartment called a pha

179 namics of infectious diseases by introducing pathogens into susceptible environments.

180 ss conditions including, but not limited to, pathogen intrusion, oxygen or nutrient starvation, prote

181 l swelling during flooding, rehydration, and pathogen invasion-but little is known about the mechanis

182 The global movement of pathogens is altering populations and communities throug

183 The development of new antibiotics for these pathogens is challenging because of the inability of mos

184 erine/threonine protein kinases in bacterial pathogens is emerging as an important strategy to better

185 ic susceptibility testing (AST) of bacterial pathogens is essential.

186 tem has evolved to cope with these potential pathogens is not well understood, and only two types of

187 e World Health Organization as a prioritized pathogen, is an emerging phlebovirus, and fatality rates

188 he warming events through the consumption of pathogen-laden carcasses by uninfected fish.

189 of a type 3 secretion system (T3SS1) in this pathogen leads to decreased intestinal colonization, whi

190 An association between pathogen life history traits and the demographic compete

191 ynamics and factors driving the dispersal of pathogens like HIV as they have difficulties capturing l

192 trol strategies based on the dynamics of the pathogen lineages derived from networks and centrality m

193 the Gram-positive, facultative intracellular pathogen Listeria monocytogenes is unusual because it ca

194 el PASTA-eSTK substrate in the Gram-positive pathogen Listeria monocytogenes.

195 Frogs were swabbed for pathogen load and skin bacterial diversity and stimulate

196 f infected individuals (prevalence) and high pathogen loads within individuals (intensity).

197 agent of COVID-19, is considered a zoonotic pathogen mainly transmitted human to human.

198 at therapeutic doses on a range of clinical pathogens, mediated by energy resources disruption, and

199 ections caused by the emerging opportunistic pathogens methanogens which escape routine detection rem

200 Intracellular pathogens mobilize host signaling pathways of their host

201 Whether pathogens modulate host circadian clock as a potential s

202 Hepatitis C virus (HCV) is a blood borne pathogen mostly transmitted via percutaneous exposure th

203 epizootic outbreak strains of the bacterial pathogen, Mycoplasma gallisepticum, which jumped from po

204 This pathogen, named severe acute respiratory syndrome corona

205 amydia muridarum are intracellular bacterial pathogens of mucosal epithelial cells.

206 tion that can rarely be answered for endemic pathogens of wildlife: what are the population- and land

207 However, in real-life spreading processes, pathogens often evolve in response to changing environme

208 gnition between R proteins and their cognate pathogens often triggers a rapid localized cell death at

209 co-eradication of Hp and select periodontal pathogens on neurodegenerative disease.

210 ecreased susceptibility to infection by host pathogen P syringae pv. tomato DC3000.

211 P assay to the established ePlex Respiratory Pathogen Panel (RPP) assay, for which we used 287 respir

212 The i.v. use of drugs transmits bloodborne pathogens, particularly viruses, making the study of CD8

213 Two or more pathogen peptides were identified in 40% of samples from

214 d lipid 654, are produced by the periodontal pathogen Porphyromonas gingivalis and can be detected in

215 Pathogens pose significant threats to pollinator health

216 eals an interaction-specific program between pathogen-presenting migratory DCs and T cells.

217 P synthesis and bacterial growth is slow and pathogen pressure from this cool-adapted fungus is high.

218 nt the spatial and temporal heterogeneity in pathogen prevalence and intensity of infection of the ch

219 a physical barrier that protects plants from pathogens, promotes tolerance to abiotic stresses and fo

220 The opportunistic pathogen Pseudomonas aeruginosa is responsible for much

221 the case of the environmental opportunistic pathogen Pseudomonas aeruginosa, it has been shown that

222 st genome sequence of a tropical rubber tree pathogen R. microporus should contribute to the better u

223 cination on B cell responses to heterologous pathogen recall antigens.

224 mechanisms that regulate the sensitivity of pathogen recognition receptors is imperative to understa

225 Streptococcus [GAS]), a major human-specific pathogen, relies on efficient nutrient acquisition for s

226 the main portal of entry for shrimp-related pathogens remain unclear, infectious diseases are diffic

227 protective antibodies to a specific neonatal pathogen represents an important host defence mechanism

228 Such fast transferable pathogens requiring practical diagnostic setups to contr

229 g to the present view on infectious diseases pathogen resistance is linked to human leukocyte antigen

230 Among them, several are involved in plant-pathogen response, which could explain why the 20rDNA li

231 nes (group A Streptococcus [GAS]) is a human pathogen responsible for a wide range of diseases.

232 Acinetobacter baumannii is a successful pathogen responsible for infections with high mortality

233 the lack of methods to quickly quantify the pathogen's response to beta-lactams.

234 d phenotypic AST for Ng is challenged by the pathogen's slow doubling time and the lack of methods to

235 The fungal pathogen Sclerotinia sclerotiorum, causal agent of white

236 onse to respiratory infection with a natural pathogen (Sendai virus).

237 unctions ranging from nutrient absorption to pathogen sensing and intestinal homeostasis.

238 on; competition for glucose between host and pathogen; significance of infection-induced anorexia; an

239 develop immune tolerance to milk-transmitted pathogens similarly to food antigens.

240 important Fe sources in Gram-positive human pathogens, since PiuA functions in the same way as SstD

241 under-appreciated virulence factor for many pathogen species.

242 romycin-treated neutrophils, suggesting that pathogen-specific factors may interact with an azithromy

243 , in vitro data demonstrate the emergence of pathogen-specific immune responses and a concomitant ris

244 s are responsible for orchestrating diverse, pathogen-specific immune responses through their differe

245 tical sensitivity = 2.5 pg/mL) to study tick pathogen-specific proteins shed in the urine of patients

246 cs (sensitivity and specificity) of relevant pathogen-specific RDTs, we used a mathematical model to

247 lix) for real-time quantitative detection of pathogen-specific sequences of nucleic acids.

248 a phagosome, but what happens when engulfed pathogens start growing?

249 tructures from two naturally competent human pathogens, Streptococcus sanguinis (ComGC(SS)) and Strep

250 ults uncover a mechanism by which an enteric pathogen subverts repair processes by targeting stem cel

251 nts an important carbon source for bacterial pathogens such as Neisseria gonorrhoeae.

252 Many gram-negative pathogens such as Neisseria meningitidis and Escherichia

253 t restricts the replication of intravacuolar pathogens such as Salmonella Here, we show that this mec

254 Some directly transmitted human pathogens, such as influenza and measles, generate susta

255 Many intracellular pathogens, such as mammalian reovirus, mimic extracellul

256 pecies of bacterial and fungal wilt-inducing pathogens suggests that microbial expansin proteins may

257 in West Africa and demonstrate the value of pathogen surveillance to identify previously undetected

258 target or bolster defense strategies in host-pathogen systems.

259 provides information on 6780 genes from 268 pathogens, tested on 210 hosts in 13,801 interactions.

260 HIV-2, a human pathogen that causes acquired immunodeficiency syndrome,

261 Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia Leg

262 of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), survival

263 is an obligate and persistent intracellular pathogen that continually drives the production of highl

264 coccus neoformans is an opportunistic fungal pathogen that infects ~280,000 people every year, causin

265 Cryptococcus neoformans is a fungal pathogen that kills almost 200,000 people each year and

266 ciency virus 1 (HIV-1) is a life-threatening pathogen that still lacks a curative therapy or vaccine.

267 Herpesviruses are ubiquitous human pathogens that cause a wide range of health complication

268 in is home to numerous arthropod-borne viral pathogens that cause febrile disease in humans.

269 antibiotic resistance has resulted in super pathogens that do not respond to most approved drugs.

270 group of intracellularly surviving bacterial pathogens that includes Mycobacterium tuberculosis, gene

271 Surprisingly, the literature suggests that pathogens that reduce yields by directly damaging harves

272 n is a mechanism by which plants recognize a pathogen threat.

273 uction of potent antibodies specific for the pathogen through a Darwinian evolutionary process known

274 onducting noninvasive surveillance for swine pathogens through the study of swine slurry.

275 d with late-term abortion, at which time the pathogen titer in placental tissue can exceed one billio

276 a mechanism by which evolution could drive a pathogen to colonize new niches, interrogation of sequen

277 The uncovered mechanism enables a pathogen to express foreign virulence genes during infec

278 s perpetual changing of the guard allows the pathogen to remain one step ahead of the acquired immune

279 However, the potential for DNA from airway pathogens to enter the circulation of cystic fibrosis (C

280 ellular processes and are often modulated by pathogens to promote infection.

281 s that potentially compromise the ability of pathogens to resist HOCl stress and therefore may increa

282 ousands of intracellular proteins, the human pathogen Toxoplasma gondii transfers a different sugar,

283 Natural infections and vaccination with a pathogen typically stimulate the production of potent an

284 is numerical advantage would be exploited by pathogens unless neutrophils from the blood stream inter

285 orts to predict novel reservoirs of zoonotic pathogens use information about host exposure and infect

286 In addition, pathogens use many strategies to manipulate host cell de

287 tterns, including large-scale variability in pathogens, vectors and associated diseases.

288 The human pathogen Vibrio cholerae typically exists as a curved ro

289 also has implications for trade-offs between pathogen virulence and transmissibility.

290 regimes for immunization against respiratory pathogens warrant further study.

291 54%) of 933 cases, at least one contributory pathogen was identified.

292 Approximately 50 pathogens were detected using, as appropriate, classic b

293 rn about potential exposure to opportunistic pathogens when reopening buildings closed due to the COV

294 phylococcus aureus is also a "high priority" pathogen which is a major cause of serious nosocomial in

295 ies complex includes important opportunistic pathogens which have become public health priorities lin

296 to spotted wilt virus (TSWV) is a generalist pathogen with one of the broadest known host ranges amon

297 to cooler lower thermal limits) compared to pathogens with predominately tropical distributions (in

298 o sequence the genomes of additional ancient pathogens, with the potential to broaden our understandi

299 quash (Cucurbita moschata), is a devastating pathogen worldwide.

300 form for detecting and monitoring waterborne pathogens would significantly aid in reducing the incide